Carbenicillin
Penicillins
A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)
Gentamicins
Pseudomonas aeruginosa
Ampicillin
Tobramycin
Kanamycin
Microbial Sensitivity Tests
Proteus
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in the intestines of humans and a wide variety of animals, as well as in manure, soil, and polluted waters. Its species are pathogenic, causing urinary tract infections and are also considered secondary invaders, causing septic lesions at other sites of the body.
Amikacin
Mezlocillin
Enterobacteriaceae
A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.
Serratia
Penicillin G
A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
Sisomicin
Klebsiella
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria whose organisms arrange singly, in pairs, or short chains. This genus is commonly found in the intestinal tract and is an opportunistic pathogen that can give rise to bacteremia, pneumonia, urinary tract and several other types of human infection.
Cefamandole
Serratia marcescens
Indenes
Cefazolin
Cephalosporins
beta-Lactams
Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.
Bacteria
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Piperacillin
Aminoglycosides
Panophthalmitis
Pseudomonas
Netilmicin
Polymyxins
beta-Lactamases
Drug Incompatibility
The quality of not being miscible with another given substance without a chemical change. One drug is not of suitable composition to be combined or mixed with another agent or substance. The incompatibility usually results in an undesirable reaction, including chemical alteration or destruction. (Dorland, 27th ed; Stedman, 25th ed)
Penicillanic Acid
Extrachromosomal Inheritance
Lactams
R Factors
Bacteroides fragilis
Drug Resistance, Microbial
Enterobacter
Modified peptidoglycan transpeptidase activity in a carbenicillin-resistant mutant of Pseudomonas aeruginosa 18s. (1/301)
A carbenicillin-resistant mutant of Pseudomonas aeruginosa 18s was found to possess peptidoglycan transpeptidase activity significantly more resistant to inhibition by benzyl penicillin, ampicillin, carbenicillin, and cephaloridine than that of the parent strain. The mutant was more resistant than the parent strain to all of the beta-lactam antibiotics tested, and 50% inhibition values for these compounds against membrane-bound model transpeptidase activity paralleled this increase. The resistance of the mutant to kanamycin, streptomycin, and chloramphenicol was unchanged. (+info)Bacteriologic cure of experimental Pseudomonas keratitis. (2/301)
Two long-term therapy trials with high concentrations of antibiotic were carried out to determine the duration of therapy required to achieve bacteriologic cure of experimental Pseudomonas keratitis in guinea pigs. In the first study, corneas still contained Pseudomonas after 4 days of continual topical therapy with either tobramycin 400 mg/ml, amikacin 250 mg/ml, ticarcillin 400 mg/ml, or carbenicillin 400 mg/ml. In an 11-day trial of topical therapy with tobramycin 20 mg/ml, 34 of 36 corneas grew no Pseudomonas after 6 or more days of therapy. The bacteriologic response to therapy in this model occurred in two phases. About 99.9% or more of the organisms in the cornea were killed in the first 24 hr of therapy. The numbers of bacteria remaining in the cornea declined gradually over the next several days until the corneas were sterile. Optimal antibiotic therapy may include two stages: initial intensive therapy with high concentrations of antibiotic applied frequently to achieve a large rapid decrease in numbers of organisms in the cornea, followed by prolonged, less intensive therapy to eradicate organisms and prevent relapse. (+info)Stability of gentamicin in serum. (3/301)
Patients' sera were divided into three portions when the initial gentamicin level was determined and were stored at -20, 4, and 25 degrees C in plastic or glass tubes. Gentamicin levels were repeated after 1 and 2 days of storage at the respective temperatures. There was no significant difference in gentamicin levels among portions, except those from a patient in renal failure with high serum concentrations of carbenicillin. (+info)Proposed ticarcillin disk control values for Escherichia coli and Pseudomonas aeruginosa: multicenter cooperative study. (4/301)
In a multicenter cooperative controlled study, individual test, accuracy, and precision control values were determined for 75-mug ticarcillin disks with Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853. (+info)An explanation for the apparent host specificity of Pseudomonas plasmid R91 expression. (5/301)
Pseudomonas aeruginosa strain 9169 has been reported to contain a plasmid that expresses resistance to carbenicillin (Cb), kanamycin (Km), and tetracycline (Tc) in Escherichia coli but resistance only to Cb in certain Pseudomonas recipients. The triply resistant plasmid in E. coli belonged to incompatibility (Inc) group P or P-1, whereas the singly resistant plasmid in P. aeruginosa was compatible with IncP-1 plasmids and other plasmids of established Inc specificity but incompatible with plasmid pSR1 that is here used to define a new Pseudomonas Inc group P-10. Additional physical and genetic studies showed that strain 9169 contained not one but two plasmids: IncP-1 plasmid R91a, determining the Cb Km Tc phenotype, and IncP-10 plasmid R91, determining Cb that differed in molecular weight and in EcoRI and BamHI restriction endonuclease recognition sites. Plasmid multiplicity rather than host effects on plasmid gene expression can account for differences in the phenotype of strain 9169 transconjugants to E. coli and P. aeruginosa. (+info)Susceptibility of the anaerobic bacteria, group D streptococci, Enterobacteriaceae, and Pseudomonas to semisynthetic penicillins: carbenicillin, piperacillin, and ticarcillin. (6/301)
Sodium piperacillin T-1220, a new semisynthetic penicillin, was tested in vitro against 297 clinical isolates of anaerobic bacteria and 669 aerobic bacteria by the conventional agar dilution method and compared with carbenicillin and ticarcillin. At a 100-mug/ml concentration the three drugs showed comparable effectiveness against the anaerobes tested. However, at 20 mug/ml, piperacillin was the most effective drug against Bacteroides fragilis, peptostreptococci, and group D streptococci. At this drug concentration only 48% of the B. fragilis strains exhibited susceptibility to carbenicillin only, 64% exhibited susceptibility to ticarcillin but 90% exhibited susceptibility to piperacillin. Similar findings were observed with peptostreptococci and group D streptococci. On a weight basis piperacillin was statistically shown to be the most effective antibiotic of the three tested against these anaerobes. At 20 mug/ml, piperacillin exhibited a statistically significant difference (P < 0.01) over carbenicillin and ticarcillin for Serratia marcescens, Escherichia coli, Klebsiella species, Klebsiella pneumoniae, Pseudomonas isolates, and Citrobacter diversus. At both 20- and 100-mug/ml concentrations, piperacillin appeared to be the most effective (calculated P < 0.01) upon Klebsiella species, K. pneumoniae, S. marcescens, and C. freundii in activity over ticarcillin and carbenicillin. (+info)BL-P1654: a bacteriostatic penicillin? (7/301)
In tube dilution studies, large discrepancies between inhibitory and bactericidal concentrations of BL-P1654 against Pseudomonas were observed. To explain these discrepancies which were not observed with carbenicillin, the kinetics of bacterial killing by these two penicillins were evaluated and compared. The kinetics of bacterial killing by both antimicrobial agents were characteristic of a penicillin, with killing initiating simultaneously with growth. Kill curves revealed the presence of a small number of cells resistant to BL-P1654 which were not detectable macroscopically. Studies on microbial resistance also showed the presence of a small but consistent number of cells resistant to BL-P1654 over a broad range of concentrations above its minimal inhibitory concentration. This pattern of resistance was not observed with carbenicillin. Thus, the discrepancies between inhibitory and bactericidal concentrations of BL-P1654 were not due to any unusual bacteriostatic activity but rather due to a small number of resistant cells whose presence could be detected only by sensitive subculturing techniques. (+info)Mechanism of intestinal absorption of an orally active beta-lactam prodrug: uptake and transport of carindacillin in Caco-2 cells. (8/301)
Absorption characteristics of carindacillin (CIPC) were investigated using Caco-2 cells, and the results were compared with those of its parent drug, carbenicillin (CBPC). Uptake of CBPC was not affected by the metabolic inhibitor or the change in extracellular pH. CBPC appeared to be taken up into Caco-2 cells by passive diffusion. In contrast, the uptake of CIPC was greater at lower extracellular pH and was inhibited in the presence of carbonyl cyanide p-(trifluoromethoxy)phenyl hydrazone, a protonophore. Also, transport of CIPC through Caco-2 cell monolayer was energy and temperature dependent. Moreover, the uptake and transport of CIPC were significantly inhibited in the presence of various monocarboxylic acids, which are the substrates of the monocarboxylic acid transport system(s), whereas the substrates of the oligopeptide transporter had no effect on the uptake or transport of CIPC. These results suggested that the absorption of CIPC may be mediated by the monocarboxylic acid transport system(s), not by the oligopeptide transporter. Furthermore, the uptake and transport of CIPC were approximately 40-fold greater than those of CBPC. Therefore, it is likely that the participation of a carrier-mediated transport in the absorption of CIPC may significantly contribute to the improved absorption of the prodrug over the parent drug. (+info)
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Pyopen (carbenicillin). *Relifex (nabumetone). *Temopen (temocillin). *Ticarpen (ticarcillin). *Timentin (ticarcillin/ ...
Carindacillin
... (INN), also known as Carbenicillin indanyl (USAN) is a penicillin antibiotic. It is a prodrug of carbenicillin. ... English AR, Retsema JA, Ray VA, Lynch JE (March 1972). "Carbenicillin indanyl sodium, an orally active derivative of ... carbenicillin". Antimicrob. Agents Chemother. 1 (3): 185-91. doi:10.1128/aac.1.3.185. PMC 444190. PMID 4558137. v t e. ...
Achromobacter xylosoxidans
Ampicillin and carbenicillin, which are penicillins, are an exception. It is variably susceptible to tetracyclines, ...
Aeromonas schubertii
It is resistant to ampicillin and carbenicillin and susceptible to most other agents. It causes infection in several species, ...
Carboxypenicillin
They belong to the penicillin family and comprise the members carbenicillin and ticarcillin. The carboxypenicillins feature the ...
Antimicrobial surface
Other antibiotics with broad antibacterial spectra are cephalothin, carbenicillin, amoxicillin, cefamandol, tobramycin, and ...
Ticarcillin
Carbenicillin is used in the clinic primarily because of its low toxicity and its utility in treating urinary tract infections ...
Actinobacillus equuli
... carbenicillin, cephalotin, and amoxycillin with clavulanic acid. The study did note it had differing results in susceptibility ...
History of penicillin
Another development of the line of true penicillins was the antipseudomonal penicillins, such as carbenicillin, ticarcillin, ...
Klebsiella pneumoniae
... many strains have acquired an extended-spectrum beta-lactamase with additional resistance to carbenicillin, amoxicillin, and ...
Penicillin
Carbenicillin Ticarcillin Temocillin Mezlocillin Piperacillin Azlocillin Clavulanic acid Sulbactam Tazobactam The term " ... Another development of the line of true penicillins was the antipseudomonal penicillins, such as carbenicillin, ticarcillin, ...
Birmingham Accident Hospital
He documented treatment of infections with Pseudomonas aeruginosa, noting that the development of carbenicillin resistance used ...
Edward Lowbury
He documented treatment of infections with Pseudomonas aeruginosa, noting that the development of carbenicillin resistance used ...
Dokdonia donghaensis
The organism is susceptible to the antibiotics tetracycline and carbenicillin, although the organism's ability to form biofilms ...
Extended-spectrum penicillin
Carbenicillin Mecillinam Pseudomonas aeruginosa § Treatment Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p917 ...
Escherichia vulneris
... and were also marginally resistant to carbenicillin, erythromycin, tetracycline, chloramphenicol, and nitrofurantoin. Twelve ...
Machine perfusion
... carbenicillin, and water to adjust the osmolality to 300-310 mosmol/kg. The perfusate was exchanged after 3.5 days storage. ...
Sisomicin
... amikacin and sisomicin combined with carbenicillin in the treatment of infections in neutropenic patients with malignancies". ...
RK2 plasmid
"Molecular Characterization of the R Factors Implicated in the Carbenicillin Resistance of a Sequence of Pseudomonas aeruginosa ...
List of MeSH codes (D03)
... carbenicillin MeSH D03.438.260.825.750.170.200 - carfecillin MeSH D03.438.260.825.750.685 - penicillin g, benzathine MeSH ... carbenicillin MeSH D03.605.084.737.750.170.200 - carfecillin MeSH D03.605.084.737.750.685 - penicillin g, benzathine MeSH ...
Lactobacillus fermentum
... carbenicillin, erythromycin, amikacin, chloramphenicol, and norfloxacin), L. fermentum was found to only be resistant to ... carbenicillin, erythromycin, amikacin, and cholorampehnicol. Lactobacillus Lactic Acid Bacteria Probiotic Zheng, Jinshui; ...
List of β-lactam antibiotics
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List of drugs: C-Ca
... carbenicillin (INN) carbenoxolone (INN) carbenzide (INN) carbetapentane carbetapentane tannate carbetimer (INN) carbetocin (INN ...
ATC code J01
... combinations J01CA01 Ampicillin J01CA02 Pivampicillin J01CA03 Carbenicillin J01CA04 Amoxicillin J01CA05 Carindacillin J01CA06 ...
Timeline of antibiotics
... carbenicillin 1967 - rifampicin 1967 - nalidixic acid, the first quinolone 1968 - clindamycin, the second lincosamide 1970 - ...
Carbenicillin
... at high doses can cause bleeding. Use of carbenicillin can cause hypokalemia by promoting potassium loss at the ... Carbenicillin is also more stable at lower pH than ampicillin. The antibiotic is highly soluble in water and is acid-labile. A ... Carbenicillin is more stable than ampicillin and results in fewer satellite colonies on selection plates. However, in most ... In molecular biology, carbenicillin may be preferred as a selecting agent (see Plasmid stabilisation technology) because its ...
Cefuroxime axetil
InChI=1S/C20H22N4O10S/c1-9(25)33-10(2)34-19(28)15-11(7-32-20(21)29)8-35-18-14(17(27)24(15)18)22-16(26)13(23-30-3)12-5-4-6-31-12/h4-6,10,14,18H,7-8H2,1-3H3,(H2,21,29)(H,22,26)/b23-13-/t10?,14-,18-/m1/ ...
Benzylpenicillin
The production of benzylpenicillin involves fermentation, recovery and purification of the penicillin.[10] The fermentation process of the production of benzylpencillin is about obtaining the product. The presence of the product in solution inhibits the reaction and reduces the product rate and yield. Thus, in order to obtain the most product and increase the rate of reaction the product, would be continuously extracted out.[11] This is done by having the mold with either glucose, sucrose, lactose, startch, or detrin, nitrate, ammonium salt, corn steep liquor, peptone, meat or yeast extract, and little amounts of inorganic salts.[12] The recovery of the benzylpencillin is the most important part of the production process because it affects the purification steps if done wrong.[10] There are many different types of techniques to recover benzyl penicillin, aqueous two-phase extraction, liquid membrane extraction, microfiltration technique, and solvent subulation[10] Extraction is more commonly ...
Meropenem
... , sold under the brandname Merrem among others, is a broad-spectrum antibiotic used to treat a variety of bacterial infections.[1] Some of these include meningitis, intra-abdominal infection, pneumonia, sepsis, and anthrax.[1] It is given by injection into a vein.[1] Common side effects include nausea, diarrhea, constipation, headache, rash, and pain at the site of injection.[1] Serious side effects include Clostridium difficile infection, seizures, and allergic reactions including anaphylaxis.[1] Those who are allergic to other β-lactam antibiotics are more likely to be allergic to meropenem.[1] Use in pregnancy appears to be safe.[1] It is in the carbapenem family of medications.[1] Meropenem usually results in bacterial death through blocking their ability to make a cell wall.[1] It is more resistant to breakdown β-lactamase producing bacteria.[1] Meropenem was patented in 1983.[2] It was approved for medical use in the United States in 1996.[1] It is on the World Health ...
Carbenicillin - Wikipedia
Carbenicillin at high doses can cause bleeding. Use of carbenicillin can cause hypokalemia by promoting potassium loss at the ... Carbenicillin is also more stable at lower pH than ampicillin. The antibiotic is highly soluble in water and is acid-labile. A ... Carbenicillin is more stable than ampicillin and results in fewer satellite colonies on selection plates. However, in most ... In molecular biology, carbenicillin may be preferred as a selecting agent (see Plasmid stabilisation technology) because its ...
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Carbenicillin - DrugBank
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Carbenicillin - wikidoc
Carbenicillin is freely soluble in water. Each Geocillin tablet contains 382 mg of carbenicillin, 118 mg of indanyl sodium ... There is limited information regarding Carbenicillin Pharmacology in the drug label. Mechanism of Action. *Free carbenicillin ... Some strains of Pseudomonas species have developed resistance to carbenicillin.. Susceptibility Testing. *Geopen (carbenicillin ... Carbenicillin is an antibiotic that is FDA approved for the treatment of infections due to Escherichia coli, Proteus mirabilis ...
What is the role of carbenicillin in the treatment of chronic bacterial prostatitis (CBP)?
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carbenicillin | C17H18N2O6S - PubChem
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Klebsiella pneumonia strains moderately resistant to ampicillin and carbenicillin: characterization of a new beta-lactamase. -...
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Carbenicillin: A Clinical and Laboratory Evaluation MELVIN I. MARKS, M.D.; THEODORE C. EICKHOFF, M.D. ... Carbenicillin therapy was given for Gram-negative infections, especially those due to Pseudomonas aeruginosa. In vitro studies ... The Carbenicillin-Gentamicin Combination Against Pseudomonas aeruginosa: Correlation of Effect with Gentamicin Sensitivity ... Carbenicillin was most effective in treating pseudomonas urinary-tract infections, although the relapse rate was high. Results ...
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The combination of carbenicillin and amikacin enhanced inhibition against all but two of the isolates. Both tobramycin and ... Comparative Activity of Tobramycin, Amikacin, and Gentamicin Alone and with Carbenicillin Against Pseudomonas aeruginosa. ... Comparative Activity of Tobramycin, Amikacin, and Gentamicin Alone and with Carbenicillin Against Pseudomonas aeruginosa ... Comparative Activity of Tobramycin, Amikacin, and Gentamicin Alone and with Carbenicillin Against Pseudomonas aeruginosa ...
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Carbenicillin, Disodium Salt - CAS 4800-94-6 - Calbiochem CAS 4800-94-6 | 205805
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Carbenicillin tablets
Carbenicillin - MedsChat
Featuring active ingredients, dosages, related medications, and Carbenicillin forums. ... Carbenicillin is also more stable at lower pH than ampicillin. Contents.... Read more Carbenicillin Details. Details May ... Carbenicillin Overview. Carbenicillin is a bactericidal antibiotic belonging to the carboxypenicillin subgroup of the ... Other drugs which contain Carbenicillin or a similar ingredient: (1 result). * GEOCILLIN Carbenicillin ...
Carbenicillin Pharmacology | acridinek
Carbenicillin is a antibacterial antibacterial acceptance to the carboxypenicillin subgroup of the penicillins. It was apparent ... Carbenicillin at top doses can could could cause bleeding. Use of carbenicillin can could could cause hypokalemia by ... Carbenicillin is aswell added abiding at lower pH than ampicillin.. The antibacterial is awful acrid in baptize and is acid- ... Carbenicillin is added abiding than ampicillin and after-effects in beneath digital colonies on alternative plates. However, in ...
A polyphosphate kinase 1 (ppk1) mutant of Pseudomonas aeruginosa exhibits multiple ultrastructural and functional defects | PNAS
Carbenicillin-Sensitivity Assays.. Strains were grown overnight in LB and subcultured into replicate flasks of LB medium to a ... Mutant Cells Fail to Survive Exposure to Carbenicillin.. A feature of P. aeruginosa is its remarkable resistance to a number of ... Among them is the loss of the high level of resistance of PA01 to the β-lactam antibiotic, carbenicillin. This loss might be ... Strains containing pHEPAK11 were grown in the presence of 300 μg/ml carbenicillin. E. coli DH5α was used for subcloning work. ...
ChemIDplus - 4697-36-3 - FPPNZSSZRUTDAP-UWFZAAFLSA-N - Carbenicillin [INN:BAN] - Similar structures search, synonyms, formulas,...
Carbenicillin (Geocillin) | Davis's Drug Guide
Find information on Carbenicillin (Geocillin) in Daviss Drug Guide including dosage, side effects, interactions, nursing ... carbenicillin is a topic covered in the Daviss Drug Guide. To view the entire topic, please sign in or purchase a subscription ... "Carbenicillin." Daviss Drug Guide, 16th ed., F.A. Davis Company, 2020. Emergency Central, emergency.unboundmedicine.com/ ... emergency/view/Davis-Drug-Guide/51128/all/carbenicillin. Quiring C, Sanoski CA, Vallerand AH. Carbenicillin. Daviss Drug Guide ...
Carbenicillin indanyl sodium | Johns Hopkins ABX Guide
Carbenicillin indanyl sodium answers are found in the Johns Hopkins ABX Guide powered by Unbound Medicine. Available for iPhone ... Carbenicillin indanyl sodium is a topic covered in the Johns Hopkins ABX Guide. To view the entire topic, please log in or ... "Carbenicillin Indanyl Sodium." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Johns Hopkins Guide, www. ... Carbenicillin Indanyl Sodium [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2021 June 22 ...
Disodium SaltAntibioticSodiumGEOCILLINPseudomonasPenicillinsCefotaximeGentamicinStrainsResistantBeta-lactamaseAntibiotics like ampicillinAmpicillin and carbenicillinAmikacinResistanceCause hypokalemiaSaltSusceptibilityAntibacterialCarboxypenicillinsDosesToxicityProdrugLower pH than ampicillinColoniesInterferesAchievableSemisyntheticVitroBacterialStableSusceptible
Disodium Salt11
- In this report, the Global and Japan Carbenicillin Disodium Salt market is valued at USD XX million in 2019 and is expected to reach USD XX million by the end of 2026, growing at a CAGR of XX% between 2019 and 2026. (satprnews.com)
- Global and Japan Carbenicillin Disodium Salt market has been broken down by major regions, with complete market estimates on the basis of products/applications on a regional basis. (satprnews.com)
- Carbenicillin Disodium Salt is a semi-synthetic penicillin antibiotic which interferes with final cell wall synthesis of susceptible bacteria. (satprnews.com)
- This report focuses on global and Japan Carbenicillin Disodium Salt QYR Global and Japan market. (satprnews.com)
- The global Carbenicillin Disodium Salt market size is projected to reach US$ XX million by 2026, from US$ XX million in 2020, at a CAGR of XX% during 2021-2026. (satprnews.com)
- Carbenicillin Disodium Salt market is segmented by region (country), players, by Type, and by Application. (satprnews.com)
- Players, stakeholders, and other participants in the global Carbenicillin Disodium Salt market will be able to gain the upper hand as they use the report as a powerful resource. (satprnews.com)
- The Carbenicillin Disodium Salt market is analysed and market size information is provided by regions (countries). (satprnews.com)
- The key regions covered in the Carbenicillin Disodium Salt market report are North America, Europe, Asia Pacific, Latin America, Middle East and Africa. (satprnews.com)
- Carbenicillin Disodium Salt market competitive landscape provides details and data information by players. (satprnews.com)
- Details included are company description, major business, company total revenue and the sales, revenue generated in Carbenicillin Disodium Salt business, the date to enter into the Carbenicillin Disodium Salt market, Carbenicillin Disodium Salt product introduction, recent developments, etc. (satprnews.com)
Antibiotic8
- Carbenicillin is a bactericidal antibiotic belonging to the carboxypenicillin subgroup of the penicillins. (wikipedia.org)
- Carbenicillin is an antibiotic that is FDA approved for the treatment of infections due to Escherichia coli , Proteus mirabilis , Morganella morganii (formerly Proteus morganii), Providencia rettgeri (formerly Proteus rettgeri), Proteus vulgaris , Pseudomonas , Enterobacter , Enterococci . (wikidoc.org)
- CARBENICILLIN (kar ben i SILL in) is a penicillin antibiotic. (covenanthealth.com)
- We describe here multiple defects in the ppk1 mutant PAOM5, including a striking compaction of the nucleoid, distortion of the cell envelope, lack of planktonic motility and exopolymer production, and susceptibility to the β-lactam antibiotic carbenicillin as well as desiccation. (pnas.org)
- We also demonstrate that the ppk1 mutant exhibits much reduced viability after exposure to a β-lactam antibiotic, carbenicillin, or the hyperosmolarity of desiccation. (pnas.org)
- Carbenicillin disodium, USP is a carboxypenicillin antibiotic and is routinely used in microbiology and plant biology as a selection agent to isolate resistant E. coli and transformed plants, respectively. (toku-e.com)
- The results of therapy with carbenicillin plus trimethoprim-sulfamethoxazole (C-T/S) were compared to those obtained with carbenicillin plus gentamicin (C-G) in a prospective double-blind study of empiric antibiotic therapy in granulocytopenic patients. (elsevier.com)
- Carindacillin (INN), also known as Carbenicillin indanyl (USAN) is a penicillin antibiotic. (wikipedia.org)
Sodium6
- Geocillin (carbenicillin indanyl sodium) is indicated in the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of the following organisms. (wikidoc.org)
- Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including GEOCILLIN(carbenicillin indanyl sodium ), and may range in severity from mild diarrhea to fatal colitis. (wikidoc.org)
- Full Text Available IALS, PENICILLINS J01CA Penicillins with extended spectrum J01CA03 Carbenicillin D02190 Carbenicillin sodium. (worldwidescience.org)
- Carbenicillin indanyl sodium is a topic covered in the Johns Hopkins ABX Guide . (hopkinsguides.com)
- Johns Hopkins Guide , www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540080/9/Carbenicillin_indanyl_sodium. (hopkinsguides.com)
- Carbenicillin disodium can be substituted for ampicillin sodium for better stability and to avoid formation of satellite colonies. (toku-e.com)
GEOCILLIN1
- Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. (drugbank.ca)
Pseudomonas11
- Carbenicillin has been shown to be effective against bacteria responsible for causing urinary tract infections including Pseudomonas aeruginosa, Escherichia coli, and some Proteus species. (wikipedia.org)
- Carbenicillin resistance in Pseudomonas aeruginosa. (bmj.com)
- Black W A , Girdwood R W . Carbenicillin resistance in Pseudomonas aeruginosa. (bmj.com)
- Carbenicillin may be effective for Enterobacteriaceae or Pseudomonas infections. (medscape.com)
- Carbenicillin therapy was given for Gram-negative infections, especially those due to Pseudomonas aeruginosa . (annals.org)
- Forty-five patients with Gram-negative infections, including 38 due to Pseudomonas , were treated with carbenicillin. (annals.org)
- Carbenicillin was most effective in treating pseudomonas urinary-tract infections, although the relapse rate was high. (annals.org)
- Carbenicillin-resistant Pseudomonas strains emerged during therapy in four patients. (annals.org)
- However, unlike most β-lactams, carbenicillin disodium is limited to primarily gram-negative bacteria including Pseudomonas aeruginosa and common enteric species. (agscientific.com)
- The activity of carbenicillin is limited to primarily gram negative bacteria including Pseudomonas aeruginosa and common enteric bacteria. (toku-e.com)
- The interactions of imipenem, carbenicillin, cefotaxime, ceftriaxone, and azlocillin with the chromosomal beta-lactamase of Pseudomonas aeruginosa were compared. (nih.gov)
Penicillins1
- Examples of this class include carboxypenicillins (carbenicillin, its acid-stable indanyl ester, and ticarcillin), ureido-penicillins (azlocillin and mezlocillin), and piperazine penicillins (piperacillin). (merckvetmanual.com)
Cefotaxime5
- Four antibiotics, kanamycin, geneticin, carbenicillin and cefotaxime, were evaluated for their effect on the regeneration of adventitious buds, shoot differentiation, rooting from regenerated shoots of Populus euphratica as well as on their control of Agrobacterium-mediated transformations. (worldwidescience.org)
- The inhibitory effects of cefotaxime and carbenicillin varied among different genotypes of Agrobacterium. (worldwidescience.org)
- The inhibition of cefotaxime on Agrobacterium C58 was stronger than that of carbenicillin .LBA4404 and their optimum concentrations were both 150 mg·L-1. (worldwidescience.org)
- The dose response assay was performed to insight into the effects of kanamycin, hygromycin, cefotaxime, and carbenicillin on the callus growth, adventitious buds regeneration and root induction of sisal. (worldwidescience.org)
- The optimum concentrations of cefotaxime and carbenicillin inhibiting Agrobacterium was determined. (worldwidescience.org)
Gentamicin3
- When therapeutically achievable concentrations were used, adding carbenicillin to gentamicin or to tobramycin enhanced inhibitory activity against those isolates susceptible (≤5 μg/ml) or moderately resistant (10 to 40 μg/ml) to the aminoglycoside. (asm.org)
- Carbenicillin-trimethoprim/sulfamethoxazole versus carbenicillin-gentamicin as empiric therapy of infection in granulocytopenic patients. (elsevier.com)
- Fingerprint Dive into the research topics of 'Carbenicillin-trimethoprim/sulfamethoxazole versus carbenicillin-gentamicin as empiric therapy of infection in granulocytopenic patients. (elsevier.com)
Strains3
- Klebsiella pneumonia strains moderately resistant to ampicillin and carbenicillin: characterization of a new beta-lactamase. (nih.gov)
- For use with carbenicillin, chloramphenicol kanamycin, and tetracycline resistant strains, and strains harboring plasmids such as pBR322, ColE1 and pUCD4 series plasmids. (bioquote.com)
- With strains made resistant by habituation, the extent of the reduction of carbenicillin resistance produced by a fixed subinhibitory dose of EDTA (200 μg per ml) did not vary with the degree of resistance even though the development of this habituated resistance was associated with a loss of sensitivity of the bacterial cells to EDTA. (microbiologyresearch.org)
Resistant6
- The use of these enhanced expression systems resulted in a 6-fold increase in the frequency of carbenicillin resistant clones. (worldwidescience.org)
- Synthetic penicillin derivative used for gene technology when carbenicillin-resistant plasmids are studied. (merckmillipore.com)
- Typically used at 30-50 µg/ml for selection of carbenicillin-resistant Escherichia coli . (merckmillipore.com)
- Carbenicillin disodium, USP is routinely used in Agrobacterium mediated transformation protocols to select for resistant agrobacterium and transformed plants. (toku-e.com)
- used carbenicillin from TOKU-E to select for resistant plants transformed with the thaumatin gene. (toku-e.com)
- To do this we measured the fitness of resistant mutants in the presence of other antibiotics (ciprofloxacin and carbenicillin) that have similar effects on bacterial growth rate but bind to different target enzymes (DNA gyrase and penicillin-binding proteins, respectively) and in 41 single-carbon source environments of varying quality. (genetics.org)
Beta-lactamase3
- Carbenicillin is used to select for cells bearing the beta-lactamase gene bla or ampR . (openwetware.org)
- Beta-lactamase also neutralizes ampicillin, but due to ampicillin's lower effectiveness, carbenicillin tends to give fewer satellite colonies and makes for more reliable cloning. (openwetware.org)
- Stable beta-lactamase derepression generally did not increase resistance to carbenicillin significantly. (nih.gov)
Antibiotics like ampicillin1
- In molecular biology, carbenicillin may be preferred as a selecting agent (see Plasmid stabilisation technology) because its breakdown results in byproducts with a lower toxicity than analogous antibiotics like ampicillin. (wikipedia.org)
Ampicillin and carbenicillin1
- Carbenicillin disodium is often used to select for cells that have been transformed with a plasmid containing the ampR gene which confers resistance to ampicillin and carbenicillin. (toku-e.com)
Amikacin2
- The serum concentration of Amikacin can be decreased when it is combined with Carbenicillin. (drugbank.ca)
- The combination of carbenicillin and amikacin enhanced inhibition against all but two of the isolates. (asm.org)
Resistance5
- A metagenomic library was constructed and functionally screened to identify genes conferring carbenicillin resistance to E. coli. (worldwidescience.org)
- Subcloning and sequence analysis showed that, besides β-lactamases, efflux pumps are not only able contribute to carbenicillin resistance but may in fact be sufficient by themselves to convey carbenicillin resistance. (worldwidescience.org)
- This suggests (1) that the reduction of habituated carbenicillin resistance by EDTA is due to a synergistic effect of the EDTA-carbenicillin combination, and (2) that the development of habituated carbenicillin resistance in Ps. (microbiologyresearch.org)
- aeruginosa , the amount of reduction of carbenicillin resistance by EDTA is variable and appears to be inversely related to the quantity of carbenicillinase produced by the bacterial strain. (microbiologyresearch.org)
- One hundred percent of ETEC and Shigella isolates showed resistance to ampicillin, carbenicillin and cephalothin. (scirp.org)
Cause hypokalemia1
- Use of carbenicillin can cause hypokalemia by promoting potassium loss at the distal convoluted tubule of the kidney. (wikipedia.org)
Salt1
- Free carbenicillin is the predominant pharmacologically active fraction of the salt. (drugbank.ca)
Susceptibility2
- The following represents carbenicillin susceptibility data for a few medically significant organisms. (wikipedia.org)
- Susceptibility studies of gram-negative bacilli against carbenicillin. (bvsalud.org)
Antibacterial1
- Carbenicillin exerts its antibacterial activity by interference with final cell wall synthesis of susceptible bacteria. (drugbank.ca)
Carboxypenicillins1
- carboxypenicillins: Carbenicillin. (laytfm.cf)
Doses2
- Carbenicillin at high doses can cause bleeding. (wikipedia.org)
- Carbenicillin at top doses can could could cause bleeding. (wordpress.com)
Toxicity1
- Carbenicillin disodium demonstrates low toxicity to plant tissues. (toku-e.com)
Prodrug1
- It is a prodrug of carbenicillin. (wikipedia.org)
Lower pH than ampicillin2
- Carbenicillin is also more stable at lower pH than ampicillin. (wikipedia.org)
- Carbenicillin is aswell added abiding at lower pH than ampicillin. (wordpress.com)
Colonies3
- Carbenicillin is more stable than ampicillin and results in fewer satellite colonies on selection plates. (wikipedia.org)
- Carbenicillin is added abiding than ampicillin and after-effects in beneath digital colonies on alternative plates. (wordpress.com)
- Substituting carbenicillin disodium for ampicillin also reduces the risk of satellite colonies appearing on growth media during extended periods of incubation. (toku-e.com)
Interferes2
- it is possible that carbenicillin interferes with an autolysin inhibitor. (drugbank.ca)
- Carbenicillin interferes with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. (toku-e.com)
Achievable1
- Carbenicillin blood levels achievable are very low, and toxic reactions as a function of overdosage should not occur systematically. (drugbank.ca)
Semisynthetic1
- Carbenicillin is a semisynthetic penicillin. (drugbank.ca)
Vitro1
- Though carbenicillin provides substantial in vitro activity against a variety of both gram-positive and gram-negative microorganisms, the most important aspect of its profile is in its antipseudomonal and antiproteal activity. (drugbank.ca)
Bacterial2
- What is the role of carbenicillin in the treatment of chronic bacterial prostatitis (CBP)? (medscape.com)
- In addition, carbenicillin has been used to regulate bacterial growth in plants, yielding low regeneration frequencies. (agscientific.com)
Stable1
- Carbenicillin was stable to hydrolysis (kcat, less than 0.1/min) and induced weakly at low concentrations. (nih.gov)
Susceptible1
- This is not representative of all species of bacteria susceptible to carbenicillin exposure. (wikipedia.org)