Carbasugars: Sugar analogs in which the ring oxygen is replaced by a methylene CH2 carbon.BooksCarbohydrates: The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES. Carbohydrates are composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n.Allied Health Occupations: Occupations of medical personnel who are not physicians, and are qualified by special training and, frequently, by licensure to work in supporting roles in the health care field. These occupations include, but are not limited to, medical technology, physical therapy, physician assistant, etc.Carbohydrate Metabolism: Cellular processes in biosynthesis (anabolism) and degradation (catabolism) of CARBOHYDRATES.Dietary Carbohydrates: Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)Library Collection Development: Development of a library collection, including the determination and coordination of selection policy, assessment of needs of users and potential users, collection use studies, collection evaluation, identification of collection needs, selection of materials, planning for resource sharing, collection maintenance and weeding, and budgeting.Textbooks as Topic: Books used in the study of a subject that contain a systematic presentation of the principles and vocabulary of a subject.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Digitonin: A glycoside obtained from Digitalis purpurea; the aglycone is digitogenin which is bound to five sugars. Digitonin solubilizes lipids, especially in membranes and is used as a tool in cellular biochemistry, and reagent for precipitating cholesterol. It has no cardiac effects.Drug Industry: That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.Biological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Fluorescent Dyes: Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.Microbiology: The study of microorganisms such as fungi, bacteria, algae, archaea, and viruses.Trehalase: An enzyme that catalyzes the conversion of alpha,alpha-trehalose and water to D-glucose. EC 126.96.36.199.Melibiose: A disaccharide consisting of one galactose and one glucose moiety in an alpha (1-6) glycosidic linkage.Lactulose: A synthetic disaccharide used in the treatment of constipation and hepatic encephalopathy. It has also been used in the diagnosis of gastrointestinal disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p887)Autophagy: The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.Disaccharides: Oligosaccharides containing two monosaccharide units linked by a glycosidic bond.Africa, Southern: The geographical area of Africa comprising ANGOLA; BOTSWANA; LESOTHO; MALAWI; MOZAMBIQUE; NAMIBIA; SOUTH AFRICA; SWAZILAND; ZAMBIA; and ZIMBABWE.Neurotoxicity Syndromes: Neurologic disorders caused by exposure to toxic substances through ingestion, injection, cutaneous application, or other method. This includes conditions caused by biologic, chemical, and pharmaceutical agents.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Medical Informatics: The field of information science concerned with the analysis and dissemination of medical data through the application of computers to various aspects of health care and medicine.Nursing Informatics: The field of information science concerned with the analysis and dissemination of data through the application of computers applied to the field of nursing.Publications: Copies of a work or document distributed to the public by sale, rental, lease, or lending. (From ALA Glossary of Library and Information Science, 1983, p181)Ferns: Seedless nonflowering plants of the class Filicinae. They reproduce by spores that appear as dots on the underside of feathery fronds. In earlier classifications the Pteridophyta included the club mosses, horsetails, ferns, and various fossil groups. In more recent classifications, pteridophytes and spermatophytes (seed-bearing plants) are classified in the Subkingdom Tracheobionta (also known as Tracheophyta).Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Nursing Homes: Facilities which provide nursing supervision and limited medical care to persons who do not require hospitalization.Substrate Specificity: A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.Home Care Services: Community health and NURSING SERVICES providing coordinated multiple services to the patient at the patient's homes. These home-care services are provided by a visiting nurse, home health agencies, HOSPITALS, or organized community groups using professional staff for care delivery. It differs from HOME NURSING which is provided by non-professionals.Homes for the Aged: Geriatric long-term care facilities which provide supervision and assistance in activities of daily living with medical and nursing services when required.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Kinetics: The rate dynamics in chemical or physical systems.Tissue Engineering: Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.Optogenetics: The combination of genetic and optical methods in controlling specific events with temporal precision in targeted cells of a functioning intact biological system.Photoreceptor Cells, Invertebrate: Specialized cells in the invertebrates that detect and transduce light. They are predominantly rhabdomeric with an array of photosensitive microvilli. Illumination depolarizes invertebrate photoreceptors by stimulating Na+ influx across the plasma membrane.Rhodopsin: A purplish-red, light-sensitive pigment found in RETINAL ROD CELLS of most vertebrates. It is a complex consisting of a molecule of ROD OPSIN and a molecule of 11-cis retinal (RETINALDEHYDE). Rhodopsin exhibits peak absorption wavelength at about 500 nm.Light: That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.Photoreceptor Cells: Specialized cells that detect and transduce light. They are classified into two types based on their light reception structure, the ciliary photoreceptors and the rhabdomeric photoreceptors with MICROVILLI. Ciliary photoreceptor cells use OPSINS that activate a PHOSPHODIESTERASE phosphodiesterase cascade. Rhabdomeric photoreceptor cells use opsins that activate a PHOSPHOLIPASE C cascade.Photoreceptor Cells, Vertebrate: Specialized PHOTOTRANSDUCTION neurons in the vertebrates, such as the RETINAL ROD CELLS and the RETINAL CONE CELLS. Non-visual photoreceptor neurons have been reported in the deep brain, the PINEAL GLAND and organs of the circadian system.Opsins: Photosensitive proteins in the membranes of PHOTORECEPTOR CELLS such as the rods and the cones. Opsins have varied light absorption properties and are members of the G-PROTEIN-COUPLED RECEPTORS family. Their ligands are VITAMIN A-based chromophores.Areca: A plant genus of the family ARECACEAE. Members contain ARECOLINE and CATECHIN. The leaves and nuts have been used as masticatories, stimulants, and astringents in traditional medicine. The common name of betel is also used for PIPER BETLE. The common name of catechu is sometimes used for ACACIA CATECHU.Tobacco, Smokeless: Powdered or cut pieces of leaves of NICOTIANA TABACUM which are inhaled through the nose, chewed, or stored in cheek pouches. It includes any product of tobacco that is not smoked.Moths: Insects of the suborder Heterocera of the order LEPIDOPTERA.Lepidoptera: A large order of insects comprising the butterflies and moths.Nucleopolyhedrovirus: A genus of the family BACULOVIRIDAE, subfamily Eubaculovirinae, characterized by the formation of crystalline, polyhedral occlusion bodies in the host cell nucleus. The type species is Autographa californica nucleopolyhedrovirus.vif Gene Products, Human Immunodeficiency Virus: Proteins encoded by the VIF GENES of the HUMAN IMMUNODEFICIENCY VIRUS.Entamoeba: A genus of ameboid protozoa characterized by the presence of beaded chromatin on the inner surface of the nuclear membrane. Its organisms are parasitic in invertebrates and vertebrates, including humans.
Nucleotidylation of unsaturated carbasugar in validamycin biosynthesis. (1/1)(+info)
RCSB PDB - 3VDN: Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP Macromolecule...
3VDN: Crystal Structure of the VldE, the pseudo-glycosyltransferase, which catalyzes non-glycosidic C-N coupling in Validamycin A biosynthesis
Structural snapshots for mechanism-based inactivation of a glycoside hydrolase by cyclopropyl-carbasugars - University...
Structural snapshots for mechanism-based inactivation of a glycoside hydrolase by cyclopropyl-carbasugars. Research output: ...https://risweb.st-andrews.ac.uk/portal/en/researchoutput/structural-snapshots-for-mechanismbased-inactivation-of-a-glycoside-hydrolase-by-cyclopropylcarbasugars
Pandey P[au] - PubMed - NCBI
Antileishmanial Carbasugars from Geosmithia langdonii.. Malak LG, Ibrahim MA, Moharram AM, Pandey P, Tekwani B, Doerksen RJ, ...https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Pandey+P%5Bau%5D&dispmax=50
Advances in Carbohydrate Chemistry and Biochemistry, Volume 59 - 1st Edition
5. Hydrazine derivatives of carba sugars and related compounds. Description. Since its inception in 1945, Advances in ...https://www.elsevier.com/books/advances-in-carbohydrate-chemistry-and-biochemistry/horton/978-0-12-007259-0
Valienol - Wikipedia
Petr Sedmera; Petr Halada & Stanislav Pospisil (2009). "New carbasugars from Streptomyces lincolnensis". Mag. Reson. Chem. 47: ...https://en.wikipedia.org/wiki/Valienol
Advances in Carbohydrate Chemistry and Biochemistry, Volume 48 - 1st Edition
T. Suami and S. Ogawa, Carba-Sugars Chemistry of (Pseudo-Sugars) and Their Derivatives. ...https://www.elsevier.com/books/advances-in-carbohydrate-chemistry-and-biochemistry/tipson/978-0-12-007248-4
Bioactive Carbohydrates and Recently Discovered Analogues as Chemotherapeutics | Bentham Science
Keywords:carbohydrates, nucleosides, carbasugars, antibiotics, glycopeptide conjugates, chemotherapeutics. Abstract: Infectious ...http://www.eurekaselect.com/80194/article/bioactive-carbohydrates-and-recently-discovered-analogues-chemotherapeutics?tracking-code=4
Chemical Intermediates and Tools for Organic SynthesisAminoethylphosphonic acid, Ala(P) Carbasugars Chiral Epoxides ...https://www.biosynth.com/en/search/search.html?searchText=indole
Molecular Basis for Trehalase Inhibition Revealed by the Structure of Trehalase in Complex with Potent Inhibitors - Gibson -...
Silvia Roscales, Joaquín Plumet, Biosynthesis and Biological Activity of Carbasugars, International Journal of Carbohydrate ...http://onlinelibrary.wiley.com/doi/10.1002/anie.200604825/full
Department of Biosciences and Informatics - Research Output - Keio University
Takai, T., Higaki, K., Aguilar-Moncayo, M., Mena-Barragán, T., Hirano, Y., Yura, K., Yu, L., Ninomiya, H., García-Moreno, M. I., Sakakibara, Y., Ohno, K., Nanba, E., Ortiz Mellet, C., García Fernández, J. M. & Suzuki, Y., 2013 Mar, In : Molecular Therapy. 21, 3, p. 526-532 7 p.. Research output: Contribution to journal › Article ...https://keio.pure.elsevier.com/en/organisations/1611-department-of-biosciences-and-informatics/publications/?type=%2Fdk%2Fatira%2Fpure%2Fresearchoutput%2Fresearchoutputtypes%2Fcontributiontojournal%2Farticle&ordering=title&descending=false
Kudos - helping increase the reach and impact of research
Synthesis of Spiro Carba-Sugars by Ring-Closing Metathesis. Published in:European Journal of Organic Chemistry. Publication ... Synthesis of Amino Carba Sugars and Conformationally Restricted Polyhydroxyγ-Amino Acids from (−)-Quinic Acid. Published in: ... Synthesis of carba-sugars from (−)-quinic acid. Published in:Tetrahedron Letters. Publication date:2001-06-01 ... ChemInform Abstract: Synthesis of Carba-Sugars from (-)-Quinic Acid.. Published in:ChemInform. Publication date:2010-05-24 ...https://www.growkudos.com/profiles/3330
From vinyl pyranoses to carbasugars by an iron-catalyzed reaction complementary to classical Ferrier carbocyclisation. Chemical ...http://iictindia.org/DIICT.aspx?NODE=mmi&Header=31
Home - Biosynth Direct Store
Carbasugars and substituted cyclopentanes are now available at Biosynth for your research or manufacturing needs. ...https://www.biosynth.com/index.php
Institute of Organic Chemistry (6410) - Research Outputs - Graz University of Technology
FURANOID CARBASUGARS AS GH 20 HEXOSAMINIDASE INHIBITORS AND POTENTIAL PHARMACOLOGICAL CHAPERONES. Wolfsgruber, A., Nasseri, S. ...https://graz.pure.elsevier.com/en/organisations/institute-of-organic-chemistry-6410/publications/
Thus, imino sugars (1), isoimino sugars (2) and amine substituted carbasugars (3) may be distinguished as the main scaffolds. ... Amongst the various types of inhibitors, low molecular weight iminosugars, carbasugars and certain types of highly ... we are currently exploring isoimino sugars as well as selected carba sugars both of which allow for structural modifications ...https://www.tugraz.at/en/institutes/orgc/forschung/arbeitsgruppe-stuetz/forschungsthemen/
Glycomimetic - Wikipedia
The molecules produced in this way would be called carbasugars or C-glycosides, thiosugars or thioglycosides, or iminosugars or ...https://en.wikipedia.org/wiki/Glycomimetic
Divergent Reactions for Racemates Catalytic Enantioselective and Regiodivergent Nitroso DielsЦAlder Reactions.
Received: April 13, 2007 Published online: July 25, 2007 . Keywords: asymmetric catalysis · carbasugars · copper · ... which belongs to the class of pseudosugars or carbasugars with interesting biological activity. To this end the N O bond in ... and the products obtained are valuable compounds for the synthesis of biologically interesting carbasugars. We believe that ...https://www.docme.ru/doc/1929616/divergent-reactions-for-racemates--catalytic--enantiosele.
Full Publication List - Concepcion Gonzalez Bello Web Page
Synthesis of Spiro Carba-sugars by Ring-Closing Metathesis. C. González-Bello*, L. Castedo and F. J. Cañada. Eur. J. Org. Chem. ... Synthesis of Carba-sugars from (-)-Quinic Acid. M. Carballido, L. Castedo and C. González-Bello*. Tetrahedron Letters 2001, 42 ... Synthesis of Amino Carba-sugars and Conformationally Restricted Polyhydroxy-gamma-amino Acids from (−)-Quinic Acid. M. ...https://www.gonzalezbello.com/publications/full-publication-list/
IX - Mayer/Möglich: Organization of SPP 1926
Carba-sugars activate the glmS-riboswitch from Staphylococcus aureus. Lu?nse C.E., Schmidt M., Wittmann V., und Mayer G. ACS ...http://spp1926.de/projects/ix-mayermoeglich/
Institut Parisien de Chimie Moléculaire - Publications
Mots-clés : carbasugars, conformational equilibrium, fluorine, GOBS, L-idose, NMR spectroscopy, POLE 3. ...http://ipcm.fr/publications-644
Browse by [email protected]
Synthesis of alpha- and beta-galactose, alpha-talose and alpha-fucopyranose carbasugars. In: Tetrahedron Letters, 41 (18). pp. ...http://eprints.iisc.ernet.in/view/people/Lakshminath=3ASripada=3A=3A.html
Items where Year is [email protected]
Synthesis of alpha- and beta-galactose, alpha-talose and alpha-fucopyranose carbasugars. In: Tetrahedron Letters, 41 (18). pp. ...http://eprints.iisc.ernet.in/view/year/2000.default.html
Cipro south african patent office : Buying hydrochlorothiazide online
o-aryl and o-heteroaryl carbasugars" has been granted by the African Regional. and the patent office of South. Patent Office ...http://www.uppereyelid.net/zytym/cipro-south-african-patent-office-lys.php
Non-glycosidically linked pseudodisaccharides : thioethers, sulfoxides, sulfones, ethers, selenoethers, and their binding to...
Also included is the development of a novel synthetic route from cheap D-fructose to three mannose-mimicking carbasugars using ... Chapters 2 and 3 describe synthetic efforts for producing carbasugars, and include the first synthesis of 1,2-bis-epi- ...http://su.diva-portal.org/smash/record.jsf?pid=diva2%3A354059&c=282&searchType=SIMPLE&language=no&query=&af=%5B%5D&aq=%5B%5B%7B%22organisationId%22%3A%22631%22%7D%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
... provides an overview of common techniques for the synthesis of carbasugars and C-glycosides, reviews the syntheses published to ...https://www.journaltocs.ac.uk/index.php?action=browse&subAction=pub&publisherID=317&journalID=17394&pageb=1&userQueryID=&sort=&local_page=&sorType=&sorCol=
School of Biology | University of St Andrews
... hydrolase by cyclopropyl-carbasugars Angewandte Chemie International Edition, vol 55, no. 48, pp. 14978-14982. DOI: 10.1002/ ...http://biology.st-and.ac.uk/contact/staffProfile.aspx?sunid=tmg
- Amongst the various types of inhibitors, low molecular weight iminosugars, carbasugars and certain types of highly functionalised, water-soluble bicyclic alkaloids have frequently been exploited. (tugraz.at)
- The molecules produced in this way would be called carbasugars or C-glycosides, thiosugars or thioglycosides, or iminosugars or glycosylamines. (wikipedia.org)