One of the phthalimide fungicides.
Chemicals that kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc.
The imide of phthalic acids.
The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.
Insects of the suborder Heterocera of the order LEPIDOPTERA.
A plant genus in the family ROSACEAE, order Rosales, subclass Rosidae. It is best known as a source of the edible fruit (apple) and is cultivated in temperate climates worldwide.
Woody, usually tall, perennial higher plants (Angiosperms, Gymnosperms, and some Pterophyta) having usually a main stem and numerous branches.
A plant genus in the family ROSACEAE, order Rosales, subclass Rosidae. It is best known as a source of edible fruits such as apricot, plum, peach, cherry, and almond.
A genus of the family BACULOVIRIDAE, subfamily Eubaculovirinae, characterized by ovicylindrical occlusion bodies. The type species is Cydia pomonella granulovirus.
The encapsulated embryos of flowering plants. They are used as is or for animal feed because of the high content of concentrated nutrients like starches, proteins, and fats. Rapeseed, cottonseed, and sunflower seed are also produced for the oils (fats) they yield.

Characterization of Trp(+) reversions in Escherichia coli strain WP2uvrA. (1/15)

The Escherichia coli strain WP2uvrA is widely used in general mutagenicity screening tests because of its high sensitivity to many kinds of mutagens and it serves as a supplement to the standard Salmonella typhimurium tester strains. In contrast to Salmonella His(+) revertants, E.coli Trp(+) revertants have not been characterized at the molecular level. In this study we found that in the trpE65 allele of WP2uvrA the triplet that codes for the fourth amino acid from the N-terminus of anthranilate synthetase was an ochre stop codon (TAA) instead of a glutamine codon (CAA). In spontaneous Trp(+) revertants the ochre codon had been changed to glutamine (CAA), lysine (AAA), glutamic acid (GAA), leucine (TTA), serine (TCA) or tyrosine (TAC, TAT). Since tryptophan prototrophy could also be restored by ochre suppressor mutations at the anticodon sites in the genes for tRNA(Glu) (glnU), tRNA(Lys) (lysT) and tRNA(Tyr) (tyrT, tyrU), the Trp(+) reversion system with E.coli WP2uvrA detected five types of base substitutions, A.T-->T.A, A.T-->C.G, A.T-->G.C, G.C-->A.T and G.C-->T.A. About 30-50% of Trp(+) revertants induced by N-ethyl-N'-nitro-N-nitrosoguanidine, captan and angelicin plus UVA irradiation were attributable to reversion at the trpE65 ochre locus; the others were attributable to suppressor mutations. In contrast, almost all revertants induced by N-methyl-N'-nitro-N-nitrosoguanidine, 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone and furylfuramide were caused by suppressor mutations. Thus, the high mutagen sensitivity of WP2uvrA is due to several target sites consisting of A.T base pairs (trpE65, lysT) and G.C base pairs (glnU, tyrT, tyrU).  (+info)

Induction of hsp70 in transgenic Drosophila: biomarker of exposure against phthalimide group of chemicals. (2/15)

The expression of stress genes is suggested to be a potentially sensitive indicator of any chemical or physical assault. This led us to explore the possibility of using expression of one of the major stress genes, hsp70, in Drosophila as a biomarker against phthalimide group of chemicals, which may accordingly provide an early indication of exposure to these hazardous chemicals. We exposed third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg(9) to different concentrations of the test chemicals (Captan, Captafol and Folpet) for various time intervals (2-48 h) to evaluate expression of hsp70 by X-gal staining, ONPG assay and whole organ in situ immunohistochemistry. The study was further extended to examine the effect of the said chemicals on development of the organism and tissue damage occurring in them, thus raising the possibility of evaluating comparative deleterious effect inducing potential of the test chemicals. Our results showed a strong hsp70 expression in the Captafol-exposed larvae followed by weaker expression in Captan- and Folpet-treated larvae. The effect was further reflected on development as revealed by a delay in emergence of the flies by 3 days in 200 ppm Captafol-exposed group. Hsp70 was found not to be induced at 0.0002 ppm Captafol and at 0.002 ppm Captan and Folpet. The present study suggests that (a). hsp70 induction is sensitive enough to be used as a biomarker against phthalimide group of chemicals, (b). amongst the three test chemicals, Captafol is the most deleterious compound followed by Captan and Folpet, (c). 0.0002 ppm for Captafol and 0.002 ppm for Captan and Folpet, respectively, can be regarded as no observed adverse effect level (NOAEL).  (+info)

Urine mutagenicity and lymphocyte DNA damage in fruit growers occupationally exposed to the fungicide captan. (3/15)

AIMS: To determine haematological parameters, urine mutagenicity (on three Salmonella typhimurium strains), and DNA damage (using the comet assay) in mononuclear leucocytes of farmers before and after a one-day spraying period of pear and apple trees with the fungicide captan in usual conditions. METHODS: Fruit growers were exposed to captan during the 1998 (n = 12) and/or the 2000 spraying seasons (n = 17). Biological samples were collected on the morning of the day of spraying (S1), the evening after spraying (S2), and the morning of the day after (S3). The UK Predictive Operator Exposure Model (UK-POEM) was used to quantify pesticide exposure intensity. RESULTS: No effect was observed on haematological parameters for these two spraying seasons. Proportions of mutagenic urine samples did not significantly differ between S1 and S2/S3 sampling points. In contrast with strains TA97a and YG1041 mainly sensitive to frameshift mutations, a positive trend was observed between the difference (S3-S1) of mutagenic power on strain TA102 detecting base-pair mutations and the exposure predicted value given by UK-POEM, mainly due to parameters related to protective clothing. No significant variations in DNA damage levels were observed between S1 and S3, nor were correlations observed with parameters of pesticide exposure. CONCLUSIONS: A one-day spraying period with captan and other pesticides does not significantly induce DNA damages in mononuclear leucocytes. In contrast, an inefficient protective clothing could correlate with an increase in urine mutagenicity as assessed by the TA102 tester strain.  (+info)

Captan exposure and evaluation of a pesticide exposure algorithm among orchard pesticide applicators in the Agricultural Health Study. (4/15)

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Rhinitis associated with pesticide use among private pesticide applicators in the agricultural health study. (5/15)

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Tetrabutylammonium bromide media aza-Michael addition of 1,2,3,6-tetrahydrophthalimide to symmetrical fumaric esters and acrylic esters under solvent-free conditions. (6/15)

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Determinants of captan air and dermal exposures among orchard pesticide applicators in the Agricultural Health Study. (7/15)

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Biological monitoring of pesticide exposures in residents living near agricultural land. (8/15)

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Captane, N-Trichloromethylmercapto-4-cyclohexene-1,2-dicarboximide Odorless, white, crystalline powder. [fungicide] [Note: Commercial product is a yellow powder with a pungent odor.]
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  • Wettable powders of the fungicide captan (CASRN #133-06-2) are applied in agricultur e by spraying over fields, applying onto the soil, or by dipping roots to be planted into a concentrated solution. (cdc.gov)
  • Charles Nii Armah Mensah popularly known Shatta Wale has today hinted that he has a new music with Captan to be released soon. (ghmediahub.com)
  • Captan is a widely used antifungal pesticide whose potential to cause cancer in humans is uncertain. (nih.gov)
  • Small groups of farmers participated in studies that measured actual exposures to certain pesticides (e.g., 2,4-D and captan) during different stages of farming and pesticide use. (nih.gov)
  • Poisson regression analysis was used to estimate relative risks (RR) for cancer subtypes by tertiles of captan exposure. (nih.gov)
  • Potential for dermal contact exists with such applications, the manufacture of captan, and its formulating. (cdc.gov)
  • Nonpolymer applications include the manufacture of agricultural fungicides (Captan and Captofol), sulfolane (an industrial solvent), and anthraquinone dyes. (cdc.gov)
  • Ara-B x Captan - Hustle mp3 download. (mauliadvise.com)
  • CHECK OUT Ara-B - Follow Who Know Road Ara-B x Captan - Hustle [Download] Nana Akosua Frimpong (Maulibaby)My name is Nana Akosua Frimpong But You can also call me MauliBaby. (mauliadvise.com)
  • An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Captan (133-06-2). (nih.gov)
  • The aim of this study was to assess the permeation of a wettable-powder formulation (48.9% captan and 1.1 % related derivatives) as it would be sprayed in agricultur e. (cdc.gov)
  • A bioassay of technical-grade captan for possible carcinogenicity was conducted by administering the test material in feed to Osborne-Mendel rats and B6C3F1 mice. (nih.gov)
  • The aim of this study was to characterize and compare nine types of powder-free, unlined, and unsupported nitrile gloves using attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectrometry to assess suitability for surface infrared analysis of the dicarboximide fungicide Captan. (cdc.gov)
  • Captan is a broad-spectrum fungicide which inhibits mycelial growth from germinating fungus spores. (nih.gov)
  • Because captan is a nonpersistent fungicide, directions for use indicate that it should be reapplied every week as necessary to maintain control. (nih.gov)
  • It is concluded that under the conditions of this bioassay, tumors in the duodenum of B6C3F1 mice were associated with treatment with captan, but there was no convincing evidence that the tumors observed in Osborne-Mendel rats were related to treatment. (nih.gov)
  • Within glove, between glove, and between lot variabilities were measured for 13 gloves from 5 manufacturers at 740, 1124, 1252, and 1735 cm-1, the characteristic Captan peak wavelengths. (cdc.gov)
  • Groups of 50 rats of each sex were administered one of two doses of captan for 80 weeks, then observed for 33 or 34 weeks. (nih.gov)
  • Mixed-effect models were used to evaluate the correlation between the adjusted and unadjusted algorithm and urinary captan metabolite levels. (nih.gov)
  • Genetic Toxicity Evaluation of Captan in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)