Hard or soft soluble containers used for the oral administration of medicine.
An envelope of loose gel surrounding a bacterial cell which is associated with the virulence of pathogenic bacteria. Some capsules have a well-defined border, whereas others form a slime layer that trails off into the medium. Most capsules consist of relatively simple polysaccharides but there are some bacteria whose capsules are made of polypeptides.
Non-invasive, endoscopic imaging by use of VIDEO CAPSULE ENDOSCOPES to perform examination of the gastrointestinal tract, especially the small bowel.
The sac enclosing a joint. It is composed of an outer fibrous articular capsule and an inner SYNOVIAL MEMBRANE.
The thin noncellular outer covering of the CRYSTALLINE LENS composed mainly of COLLAGEN TYPE IV and GLYCOSAMINOGLYCANS. It is secreted by the embryonic anterior and posterior epithelium. The embryonic posterior epithelium later disappears.
A pill sized videocamera encased in a capsule. It is designed to be swallowed and subsequently traverse the gastrointestinal tract while transmitting diagnostic images along the way.
WHITE MATTER pathway, flanked by nuclear masses, consisting of both afferent and efferent fibers projecting between the WHITE MATTER and the BRAINSTEM. It consists of three distinct parts: an anterior limb, posterior limb, and genu.
An extracellular layer outside the cell wall of a fungus composed of polysaccharides. It may serve a protective role amongst others.
A double-walled epithelial capsule that is the bulbous closed proximal end of the kidney tubular system. It surrounds the cluster of convoluted capillaries of KIDNEY GLOMERULUS and is continuous with the convoluted PROXIMAL KIDNEY TUBULE.
In vivo method of screening investigative anticancer drugs and biologic response modifiers for individual cancer patients. Fresh tumor tissue is implanted under the kidney capsule of immunocompetent mice or rats; gross and histological assessments follow several days after tumor treatment in situ.
Polysaccharides found in bacteria and in capsules thereof.
Clouding or loss of transparency of the posterior lens capsule, usually following CATARACT extraction.
The posterior aspect of the casing that surrounds the natural CRYSTALLINE LENS.
A species of the fungus CRYPTOCOCCUS. Its teleomorph is Filobasidiella neoformans.
The making of a continuous circular tear in the anterior capsule during cataract surgery in order to allow expression or phacoemulsification of the nucleus of the lens. (Dorland, 28th ed)
A transparent, biconvex structure of the EYE, enclosed in a capsule and situated behind the IRIS and in front of the vitreous humor (VITREOUS BODY). It is slightly overlapped at its margin by the ciliary processes. Adaptation by the CILIARY BODY is crucial for OCULAR ACCOMMODATION.
The anterior aspect of the casing that surrounds the natural CRYSTALLINE LENS.
Instruments for the visual examination of the interior of the gastrointestinal tract.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.
Endoscopic examination, therapy or surgery of the gastrointestinal tract.
Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.
Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint.
A procedure for removal of the crystalline lens in cataract surgery in which an anterior capsulectomy is performed by means of a needle inserted through a small incision at the temporal limbus, allowing the lens contents to fall through the dilated pupil into the anterior chamber where they are broken up by the use of ultrasound and aspirated out of the eye through the incision. (Cline, et al., Dictionary of Visual Science, 4th ed & In Focus 1993;1(1):1)
The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.
Tablets coated with material that delays release of the medication until after they leave the stomach. (Dorland, 28th ed)
Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
Infection with a fungus of the species CRYPTOCOCCUS NEOFORMANS.
Surgical procedure to relax the JOINT CAPSULE tissues in a joint that has a reduced range of motion due to CONTRACTURE or TISSUE ADHESIONS or joint deformities.
Dosage forms of a drug that act over a period of time by controlled-release processes or technology.
The removal of a cataractous CRYSTALLINE LENS from the eye.
Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)
Chronic inflammation and granuloma formation around irritating foreign bodies.
Artificial implanted lenses.
A gram-positive organism found in the upper respiratory tract, inflammatory exudates, and various body fluids of normal and/or diseased humans and, rarely, domestic animals.
Devices implanted to control intraocular pressure by allowing aqueous fluid to drain from the anterior chamber. (Hoffman, Pocket Glossary of Ophthalmologic Terminology, 1989)
An enzyme that catalyzes the oxidation of UDPglucose to UDPglucuronate in the presence of NAD+. EC
Proteins found in any species of bacterium.
Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
A peptide that is a homopolymer of glutamic acid.
The giving of drugs, chemicals, or other substances by mouth.
A species of bacteria that causes ANTHRAX in humans and animals.
Insertion of an artificial lens to replace the natural CRYSTALLINE LENS after CATARACT EXTRACTION or to supplement the natural lens which is left in place.
Passage of food (sometimes in the form of a test meal) through the gastrointestinal tract as measured in minutes or hours. The rate of passage through the intestine is an indicator of small bowel function.
The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)
The transference of pancreatic islets within an individual, between individuals of the same species, or between individuals of different species.
Polymers of silicone that are formed by crosslinking and treatment with amorphous silica to increase strength. They have properties similar to vulcanized natural rubber, in that they stretch under tension, retract rapidly, and fully recover to their original dimensions upon release. They are used in the encapsulation of surgical membranes and implants.
Process of determining and distinguishing species of bacteria or viruses based on antigens they share.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
A mitosporic Tremellales fungal genus whose species usually have a capsule and do not form pseudomycellium. Teleomorphs include Filobasidiella and Fidobasidium.
The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
A species of gram-negative, aerobic BACTERIA. It is a commensal and pathogen only of humans, and can be carried asymptomatically in the NASOPHARYNX. When found in cerebrospinal fluid it is the causative agent of cerebrospinal meningitis (MENINGITIS, MENINGOCOCCAL). It is also found in venereal discharges and blood. There are at least 13 serogroups based on antigenic differences in the capsular polysaccharides; the ones causing most meningitis infections being A, B, C, Y, and W-135. Each serogroup can be further classified by serotype, serosubtype, and immunotype.
Enzymes that catalyze the transfer of glycosyl groups to an acceptor. Most often another carbohydrate molecule acts as an acceptor, but inorganic phosphate can also act as an acceptor, such as in the case of PHOSPHORYLASES. Some of the enzymes in this group also catalyze hydrolysis, which can be regarded as transfer of a glycosyl group from the donor to water. Subclasses include the HEXOSYLTRANSFERASES; PENTOSYLTRANSFERASES; SIALYLTRANSFERASES; and those transferring other glycosyl groups. EC 2.4.
The functional hereditary units of BACTERIA.
A broad family of synthetic organosiloxane polymers containing a repeating silicon-oxygen backbone with organic side groups attached via carbon-silicon bonds. Depending on their structure, they are classified as liquids, gels, and elastomers. (From Merck Index, 12th ed)
Pathological development in the JEJUNUM region of the SMALL INTESTINE.
Endoscopy of the small intestines accomplished while advancing the endoscope into the intestines from the stomach by alternating the inflation of two balloons, one on an innertube of the endoscope and the other on an overtube.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).
Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)
Term used to designate tetrahydroxy aldehydic acids obtained by oxidation of hexose sugars, i.e. glucuronic acid, galacturonic acid, etc. Historically, the name hexuronic acid was originally given to ascorbic acid.
Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Salts of alginic acid that are extracted from marine kelp and used to make dental impressions and as absorbent material for surgical dressings.
The natural bactericidal property of BLOOD due to normally occurring antibacterial substances such as beta lysin, leukin, etc. This activity needs to be distinguished from the bactericidal activity contained in a patient's serum as a result of antimicrobial therapy, which is measured by a SERUM BACTERICIDAL TEST.
Substances elaborated by bacteria that have antigenic activity.
Elements of limited time intervals, contributing to particular results or situations.
A physical property showing different values in relation to the direction in or along which the measurement is made. The physical property may be with regard to thermal or electric conductivity or light refraction. In crystallography, it describes crystals whose index of refraction varies with the direction of the incident light. It is also called acolotropy and colotropy. The opposite of anisotropy is isotropy wherein the same values characterize the object when measured along axes in all directions.
An acute infection caused by the spore-forming bacteria BACILLUS ANTHRACIS. It commonly affects hoofed animals such as sheep and goats. Infection in humans often involves the skin (cutaneous anthrax), the lungs (inhalation anthrax), or the gastrointestinal tract. Anthrax is not contagious and can be treated with antibiotics.
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.
A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.
Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
A group of naturally occurring N-and O-acyl derivatives of the deoxyamino sugar neuraminic acid. They are ubiquitously distributed in many tissues.
The lipopolysaccharide-protein somatic antigens, usually from gram-negative bacteria, important in the serological classification of enteric bacilli. The O-specific chains determine the specificity of the O antigens of a given serotype. O antigens are the immunodominant part of the lipopolysaccharide molecule in the intact bacterial cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.
A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.
Transmission of the readings of instruments to a remote location by means of wires, radio waves, or other means. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.
Shiny, flexible bands of fibrous tissue connecting together articular extremities of bones. They are pliant, tough, and inextensile.
Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS.
A necessary enzyme in the metabolism of galactose. It reversibly catalyzes the conversion of UDPglucose to UDPgalactose. NAD+ is an essential component for enzymatic activity. EC
A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
A species of gram-positive, coccoid bacteria isolated from skin lesions, blood, inflammatory exudates, and the upper respiratory tract of humans. It is a group A hemolytic Streptococcus that can cause SCARLET FEVER and RHEUMATIC FEVER.
Acquired degenerative dilation or expansion (ectasia) of normal BLOOD VESSELS, often associated with aging. They are isolated, tortuous, thin-walled vessels and sources of bleeding. They occur most often in mucosal capillaries of the GASTROINTESTINAL TRACT leading to GASTROINTESTINAL HEMORRHAGE and ANEMIA.
Gram-negative, non-motile, capsulated, gas-producing rods found widely in nature and associated with urinary and respiratory infections in humans.
Use of plants or herbs to treat diseases or to alleviate pain.
Small containers or pellets of a solid drug implanted in the body to achieve sustained release of the drug.
An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
A product formed from skin, white connective tissue, or bone COLLAGEN. It is used as a protein food adjuvant, plasma substitute, hemostatic, suspending agent in pharmaceutical preparations, and in the manufacturing of capsules and suppositories.
Polymerized methyl methacrylate monomers which are used as sheets, moulding, extrusion powders, surface coating resins, emulsion polymers, fibers, inks, and films (From International Labor Organization, 1983). This material is also used in tooth implants, bone cements, and hard corneal contact lenses.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.
A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria normally found in the flora of the mouth and respiratory tract of animals and birds. It causes shipping fever (see PASTEURELLOSIS, PNEUMONIC); HEMORRHAGIC BACTEREMIA; and intestinal disease in animals. In humans, disease usually arises from a wound infection following a bite or scratch from domesticated animals.
The outermost layer of a cell in most PLANTS; BACTERIA; FUNGI; and ALGAE. The cell wall is usually a rigid structure that lies external to the CELL MEMBRANE, and provides a protective barrier against physical or chemical agents.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull).
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
The use of diffusion ANISOTROPY data from diffusion magnetic resonance imaging results to construct images based on the direction of the faster diffusing molecules.
A diagnostic technique that incorporates the measurement of molecular diffusion (such as water or metabolites) for tissue assessment by MRI. The degree of molecular movement can be measured by changes of apparent diffusion coefficient (ADC) with time, as reflected by tissue microstructure. Diffusion MRI has been used to study BRAIN ISCHEMIA and tumor response to treatment.
Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)
The motion of fluids, especially noncompressible liquids, under the influence of internal and external forces.
A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).
Transplantation of tissue typical of one area to a different recipient site. The tissue may be autologous, heterologous, or homologous.
Agents that are used to stimulate evacuation of the bowels.
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
Colloids with liquid continuous phase and solid dispersed phase; the term is used loosely also for solid-in-gas (AEROSOLS) and other colloidal systems; water-insoluble drugs may be given as suspensions.

Cephalosporin and aminoglycoside concentrations in peritoneal capsular fluid in rabbits. (1/735)

To study the penetration of antibiotics into peritoneal tissue fluid, a subcutaneous tissue capsule model was modified by implanting multiple, perforated spherical capsules in the peritoneal cavity of rabbits. Capsules became vascularized, encased in connective tissue, and filled with fluid having a mean protein concentration of 3.6 g/100 ml. Capsular fluid was obtained by percutaneous needle aspiration and assayed for antibiotic by the disk plate bioassay technique. Cephalosporins were administered intramuscularly at a dose of 30 mg/kg. Mean peak concentrations of cephaloridine and cefazolin were significantly higher than cephalothin and cephapirin in capsular fluids, but the percent penetration (ratio of capsular mean peak to serum mean peak) ranged from 8.7 to 16.9% and was not significantly different among the cephalosporins. At 24 h the capsular concentration of cefazolin was significantly greater than for the other cephalosporins (P < 0.001). Lower rabbit serum protein binding observed at high in vivo concentrations may have enabled cefazolin to penetrate capsular fluid, but in vitro protein binding studies did not confirm a decrease in serum protein binding at high concentrations within the clinical range. Kanamycin and amikacin showed comparable capsular fluid peak concentrations as did gentamicin and tobramycin. The percent penetration ranged from 15.2 to 34.5% for the aminoglycosides. The only statistical difference was that amikacin penetration was significantly higher than that for tobramycin. Mean capsular concentrations of amikacin, cefazolin, and cephaloridine compared most favorably with the minimum inhibitory concentration of gram-negative bacilli at the dosages used in this study.  (+info)

A cortisol suppression dose-response comparison of budesonide in controlled ileal release capsules with prednisolone. (2/735)

AIM: To assess the systemic effect of oral budesonide, given as Entocort controlled ileal release capsules, over a dose range of 3-15 mg/day, compared with that of a moderate dose (20 mg/day) of prednisolone. METHODS: Twenty four healthy subjects were given 3, 9 or 15 mg budesonide or 20 mg prednisolone once daily, or 4.5 mg budesonide b.d., or placebo for 5 days in a randomized, double-blind crossover study. The area under the curve (AUC) of plasma cortisol concentration and the amount of cortisol excreted in the urine were monitored. RESULTS: Both plasma and urine cortisol suppression showed a dose-response for the daily doses of budesonide. Prednisolone, 20 mg, suppressed plasma cortisol (AUC) statistically significantly more than 15 mg budesonide (P = 0.014), and 3 mg budesonide statistically significantly more than placebo (P = 0.010). No difference in AUC was detected between 9 mg and 4.5 mg budesonide b.d. Similar results for budesonide vs. placebo were obtained from urine cortisol excretion data. However, prednisolone affected urine cortisol less than it affected plasma cortisol. CONCLUSION: After 5 days of administration, budesonide controlled ileal release capsules, in both clinical (9 mg/day) and high doses (15 mg/day), affected plasma cortisol less than a moderate (20 mg/day) dose of prednisolone.  (+info)

Breast milk immune factors in Bangladeshi women supplemented postpartum with retinol or beta-carotene. (3/735)

BACKGROUND: Vitamin A supplementation of mothers postpartum may improve infant health, not only by increasing vitamin A delivery to the infant through breast milk but also by increasing delivery of milk immune factors. Our hypothesis was that postpartum supplementation with vitamin A increases milk concentrations of certain soluble immune factors. DESIGN: In a double-blind trial conducted in Matlab, Bangladesh, women at 1-3 wk postpartum were randomly assigned to receive until 9 mo postpartum 1) a single dose of 60 mg retinol as retinyl palmitate followed by daily placebos (n = 69), 2) daily doses of 7.6 mg beta-carotene (n = 72), or 3) daily placebos (n = 71). Milk samples collected at baseline and 3 mo postpartum were analyzed by enzyme-linked immunosorbent assay for secretory immunoglobulin A, lactoferrin, lysozyme, and interleukin 8; by HPLC for total retinol; and by atomic absorption spectroscopy for sodium and potassium. RESULTS: After mammary epithelial permeability (defined as an elevated Na:K) and baseline immune factor concentrations were controlled for, there were no significant treatment effects on immune factors at 3 mo. Increased mammary permeability was common (25% of women at baseline and 12% at 3 mo) and was associated with higher concentrations of milk immune factors. Low body vitamin A stores at baseline, as assessed by the modified-relative-dose-response test, were associated with a higher Na:K, but neither retinol nor beta-carotene supplementation affected the prevalence of increased mammary permeability. CONCLUSIONS: Postpartum vitamin A supplementation does not increase milk concentrations of immune factors. The causes of increased mammary epithelial permeability in this population require further study.  (+info)

Continuous delivery of human and mouse erythropoietin in mice by genetically engineered polymer encapsulated myoblasts. (4/735)

The transplantation of polymer encapsulated myoblasts genetically engineered to secrete erythropoietin (Epo) may obviate the need for repeated parenteral administration of recombinant Epo as a treatment for chronic renal failure, cancer or AIDS-associated anemia. To explore this possibility, the human and mouse Epo cDNAs under the control of the housekeeping mouse PGK-1 promoter were transfected into mouse C2C12 myoblasts, which can be terminally differentiated upon exposure to low serum-containing media. Pools releasing 150 IU human Epo per 10(6) cells per day and 390 IU mouse Epo per 10(6) cells per day were selected. Polyether-sulfone (PES) capsules loaded with approximately 200,000 transfected myoblasts from these pools were implanted on the dorsal flank of DBA/2J, C3H and C57BL/6 mice. With human Epo secreting capsules, only a transient increase in the hematocrit occurred in DBA/2J mice, whereas no significant response was detected in C3H or C57BL/6 mice. On the contrary, all mice implanted with capsules releasing mouse Epo increased their hematocrit over 85% as early as 7 days after implantation and sustained these levels for at least 80 days. All retrieved implants released Epo and contained well preserved myoblasts. Moreover most capsules were surrounded by a neovascularization. Mice transplanted with nonencapsulated C2C12 cells releasing mouse Epo showed only a transitory elevation of their hematocrit reflecting the poor engraftment of injected myoblasts. These results indicate that polymer encapsulation of genetically engineered myoblasts is a promising approach for the long-term delivery of bioactive molecules, allowing the resolution of the shortcomings of free myoblast transfer.  (+info)

Targeted chemotherapy by intratumour injection of encapsulated cells engineered to produce CYP2B1, an ifosfamide activating cytochrome P450. (5/735)

The prognosis of pancreatic adenocarcinoma is poor and current treatment ineffective. A novel treatment strategy is described here using a mouse model system for pancreatic cancer. Cells that have been genetically modified to express the cytochrome P450 2B1 enzyme are encapsulated in cellulose sulphate and implanted into pre-established tumours derived from human pancreatic cells. Cytochrome P450 2B1 converts the chemotherapeutic agent ifosfamide to toxic metabolites. Administration of ifosfamide to tumour-bearing mice that were recipients of implanted encapsulated cells results in partial or even complete tumour ablation. These results suggest that in situ chemotherapy with genetically modified cells in an immunoprotected environment may prove useful for application in man.  (+info)

Comparison of antiplatelet activity of microencapsulated aspirin 162.5 Mg (Caspac XL), with enteric coated aspirin 75 mg and 150 mg in patients with atherosclerosis. (6/735)

AIMS: A new formulation, low dose microencapsulated aspirin, permits slow absorption of aspirin and presystemic acetylation of platelet cyclo-oxygenase within the portal circulation, potentially avoiding deleterious effects on gastric and systemic prostaglandin synthesis. The objective of this study was to determine whether the administration of microencapsulated aspirin was as effective as enteric coated (EC) aspirin as an inhibitor of platelet function in patients with atherosclerosis. METHODS: One hundred and four patients were enrolled and randomised after a run in period of at least 14 days on aspirin EC 75 mg (day 0), to receive either microencapsulated aspirin 162.5 mg (n=34), aspirin EC 150 mg (n=36) or continue on aspirin EC 75 mg (n=34) for 28 days. Serum thromboxane B2 and collagen-induced platelet aggregation and release of 5-hydroxytryptamine (EC50 values) were measured on days 0 and 28. Aggregation/release EC50s were then repeated in the presence of a large dose of aspirin added in vitro to determine the EC50 at the maximum level of platelet inhibition. RESULTS: Median thromboxane B2 levels were low after 14 days run-in therapy with aspirin EC 75 mg, but significant further reductions were seen on day 28 in patients randomised to microencapsulated aspirin 162.5 mg (P=0.0368) and aspirin EC 150 mg (P=0.0004) compared with those remaining on aspirin EC 75 mg. Median EC50 s on day 28 showed small but significant increases from baseline (day 0) in aggregation in patients randomised to microencapsulated aspirin 162.5 mg (0.62-0.85, P=0.0482) and in both aggregation and release in patients randomised to aspirin EC 150 mg (0.95-1.20, P=0.0002, 8.4-11.7, P<0. 0001, respectively) signifying enhanced antiplatelet activity. No changes were seen in patients continuing on aspirin EC 75 mg. Results following addition of high dose aspirin in vitro suggest that mechanisms other than thromboxane synthesis may be operative in the long term effects of microencapsulated aspirin 162.5 mg and aspirin EC 150 mg over aspirin EC 75 mg. CONCLUSIONS: The results show good inhibition of thromboxane B2 synthesis and subsequent platelet activity by all preparations of aspirin, although both microencapsulated aspirin 162.5 mg and aspirin EC 150 mg are slightly more effective than aspirin EC 75 mg. A randomised trial is now required to determine whether microencapsulated aspirin is associated with fewer gastric side-effects.  (+info)

Improvement of mouse beta-thalassemia upon erythropoietin delivery by encapsulated myoblasts. (7/735)

The goal of the present study was to analyze if sustained delivery of elevated doses of recombinant erythropoietin (Epo), by genetically modified and immunoprotected allogenic cells, was able to correct the chronic anemia, characteristic of a spontaneous mouse model of beta-thalassemia (Hbb thal 1). Mouse C2C12 myoblast cells were transfected with a plasmid containing the mouse Epo cDNA and a mutated dihydrofolate reductase (DHFR) gene for gene amplification upon administration of increasing doses of methotrexate. In order to immunoprotect the transplanted cells, the stably modified cells were loaded into polyethersulfone microporus hollow fibers which were implanted subcutaneously into Hbb thal 1 mice. An increase in hematocrit starting 2 weeks after implantation was associated with elevated blood levels of Epo and an improved red blood cell phenotype. The latter indicated an improvement of cell morphology and membrane defects, in particular a reduced amount of free alpha hemoglobin chain, the hallmark of globin chain imbalance in beta-thalassemia. A reduction of reticulocyte count contrasting with the increase in hematocrit was also observed suggesting an improved erythrocyte survival. We conclude that the phenotype can be durably improved in some beta-thalassemic mice upon in vivo delivery of recombinant Epo by polymer encapsulated cells. Sustained elevated delivery of recombinant Epo holds promise for the treatment of beta-thalassemia-associated chronic anemia.  (+info)

Stabilized plasmid-lipid particles: construction and characterization. (8/735)

A detergent dialysis procedure is described which allows encapsulation of plasmid DNA within a lipid envelope, where the resulting particle is stabilized in aqueous media by the presence of a poly(ethyleneglycol) (PEG) coating. These 'stabilized plasmid-lipid particles' (SPLP) exhibit an average size of 70 nm in diameter, contain one plasmid per particle and fully protect the encapsulated plasmid from digestion by serum nucleases and E. coli DNase I. Encapsulation is a sensitive function of cationic lipid content, with maximum entrapment observed at dioleoyldimethylammonium chloride (DODAC) contents of 5 to 10 mol%. The formulation process results in plasmid-trapping efficiencies of up to 70% and permits inclusion of 'fusigenic' lipids such as dioleoylphosphatidylethanolamine (DOPE). The in vitro transfection capabilities of SPLP are demonstrated to be strongly dependent on the length of the acyl chain contained in the ceramide group used to anchor the PEG polymer to the surface of the SPLP. Shorter acyl chain lengths result in a PEG coating which can dissociate from the SPLP surface, transforming the SPLP from a stable particle to a transfection-competent entity. It is suggested that SPLP may have utility as systemic gene delivery systems for gene therapy protocols.  (+info)

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All subjects received all tested treatments in a randomised, open label, 3-way cross over study. The treatments were:. Single dose of 240 mg faldaprevir in a form of two soft gelatin capsules was administered orally following an overnight or at least 10 hours (h) fast prior the drug administration (Reference treatment). Single dose of 240 mg faldaprevir in a form of two soft gelatin capsules was administered orally 30 minutes (min) after a standard high-fat, high-caloric meal was served. The meal had to be completely consumed within 25 min or less.. Single dose of 240 mg faldaprevir in a form of two soft gelatin capsules was coadministered orally with 40 mg Omeprazole following an overnight or at least 10 hours (h) fast prior the drug administration following multiple dosing of 40 mg omeprazole once daily for 4 days prior the first dose of faldaprevir.. Drug administrations were separated by a washout period of at least 14 days. ...
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The aim of this study was to enhance the release rate of the hypoglycaemic agent glibenclamide from hard gelatin capsules through co-lyophilisation with sodium lauryl sulphate (SLS) and perform physical characterisation of the lyophilised product.. ...
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TY - JOUR. T1 - Physical characterization and drug release profiling for hard capsules prepared with hydroxypropylcellulose or polyethylene oxide. AU - Lee, Chien Yuan. AU - Chen, Gan Lin. AU - Sheu, Ming Thau. AU - Liu, Cheng Hsiung. PY - 2006/4. Y1 - 2006/4. N2 - In this study, hard capsule shells were made by a heat-melting method, which involved heating Polyethylene oxide (PEO, MW 200000) or hydroxypropyl cellulose (HPC, MW 80,000,100,000 and 370000) powder in a mold, followed by inserting a suitable size of pestle in a mold to coat the melted shell materials (HPC or PEO) onto pestle with a certain force. The more satisfactory were prepared at the temperature higher than melting point of corresponding polymer. The water uptake and dissolution test of various capsule shells were evaluated in acidic or basic buffer with added inorganic salt including sodium chloride, potassium chloride, calcium chloride and aluminum chloride. Propranolol hydrochloride and theophylline were selected as the ...
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0058]The stability of the capsules and pirfenidone/excipient formulations provided herein is demonstrated in the results presented in FIG. 8. The 267 mg pirfenidone capsule formulation of FIG. 6 was stored for 18 months under three different storage conditions: 25° C. and 60% relative humidity, 30° C. and 65% relative humidity, and 40° C. and 75% relative humidity. FIG. 8 shows that the dissolution of the capsule and pirfenidone/excipient formulations at 25° C. and 60% relative humidity, 30° C. and 65% relative humidity did not appreciably change over the duration of the 18 month period. The dissolution of the capsule and pirfenidone/excipient formulations at 40° C. and 75% relative humidity did not appreciably change over the initial 12 month period. The dissolution analysis was performed according to the pharmacopoeial dissolution method specified in USP29 using Apparatus 2 (paddles) with water as a solvent and a specification of Q=70% of label claim in 30 minutes. Also shown in FIG. 8, ...
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Subjects will be hospitalized to the clinical unit on the evening of Day -1. All subjects will receive 1 x 0.5mg oral dose of dutasteride (Sequence A), in the morning; Subjects will remain in the clinical unit until completion of all assessments at 24 hours post-dose on Day 2 including collection of the 24 hour post-dose PK sample. Subjects will return to the unit for the remaining PK samples at 36, 48 and 72 hours. The subject will receive or 5 x 0.1mg oral dose of dutasteride (Sequence B) in similar fashion as that of Sequence A. The two treatment sequences will be separated by a minimum washout period of 28 days to ensure that dutasteride is effectively eliminated from the subject between dosing occasions ...
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OBJECTIVE:To investigate the effect of Duyiwei(lamiophlomis rotate) capsule on the expression of proliferating cell nuclear antigen(PCNA) in Wistar rats.METHODS:40 Wistar rats,half male half female,were randomly divided into 5 groups:model group,PTCA group,Duyiwei(Lamiophlomis rotate) capsule 0.50,1.25,2.50 g/kg,positive control group(salvia miltrorrhiza tablet 1.0 g/kg).Oral administration of drugs was performed in each group,continuously 5 days.Then all rats were treated by percutaneous transluminal coronary angioplasty(PTCA) for the establishment of carotid balloon injury model.Then drug treatment continued after PTCA for 28 days.Carotid artery segment underwent routine biopsy immunohistochemistry and PCNA expression determination.RESULTS:In the normal artery,these was low level or no expression of PCNA.In the arterial intima of the model groups,33.71%was PCNA-positivewith each dose of Duyiwei capsule group showing significant differences(P0.05).CONCLUSION:Duyiwei capsule significantly inhibited the
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Captopril is an ACE inhibitor that is used for the treatment of hypertension. The purpose of this study was to encapsulate the drug in different polymer having mucoadhesive property and thus combining the advantages of microparticulates with mucoadhesive drug delivery system. The microcapsules with a coat consisting of alginate and a mucoadhesive polymer such as sodium carboxymethylcellulose (SCMC), methylcellulose, Carbopol 934P and hydroxyl propylmethylceullulose (HPMC) E15V were prepared by ionotropic gelation technique, where gelation was achieved with oppositely charged counter ions to form microparticles. The prepared microcapsules were subjected for various evaluations. The resulting microparticles were discrete, large, spherical and free-flowing. Captopril release from these microcapsules was slow and extended over longer period of time. Drug release for some formulation was diffusion controlled and others exhibited anomalous behavior. The prepared microcapsules exhibited good mucoadhesive
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Absorption Following administration of a single 0.5-mg dose of a soft gelatin capsule, time to peak serum concentrations (Tmax) of dutasteride occurs within 2 to 3 hours. Absolute bioavailability in 5 healthy subjects is approximately 60% (range: 40% to 94%). When the drug is administered with food, the maximum serum concentrations were reduced by 10% to 15%. This reduction is of no clinical significance.. Distribution Pharmacokinetic data following single and repeat oral doses show that dutasteride has a large volume of distribution (300 to 500 L). Dutasteride is highly bound to plasma albumin (99.0%) and alpha-1 acid glycoprotein (96.6%).. In a trial of healthy subjects (n = 26) receiving dutasteride 0.5 mg/day for 12 months, semen dutasteride concentrations averaged 3.4 ng/mL (range: 0.4 to 14 ng/mL) at 12 months and, similar to serum, achieved steady-state concentrations at 6 months. On average, at 12 months 11.5% of serum dutasteride concentrations partitioned into semen.. Metabolism and ...
Absorption Following administration of a single 0.5-mg dose of a soft gelatin capsule, time to peak serum concentrations (Tmax) of dutasteride occurs within 2 to 3 hours. Absolute bioavailability in 5 healthy subjects is approximately 60% (range: 40% to 94%). When the drug is administered with food, the maximum serum concentrations were reduced by 10% to 15%. This reduction is of no clinical significance. Distribution Pharmacokinetic data following single and repeat oral doses show that dutasteride has a large volume of distribution (300 to 500 L). Dutasteride is highly bound to plasma albumin (99.0%) and alpha-1 acid glycoprotein (96.6%). In a trial of healthy subjects (n = 26) receiving dutasteride 0.5 mg/day for 12 months, semen dutasteride concentrations averaged 3.4 ng/mL (range: 0.4 to 14 ng/mL) at 12 months and, similar to serum, achieved steady-state concentrations at 6 months. On average, at 12 months 11.5% of serum dutasteride concentrations partitioned into semen. Metabolism and ...
This is one of the leading pharma companies of Algeria. More than a laboratory, it aims to be a real player in public health in Algeria. By placing more than 50 million sales units on the market annually, this supports health practitioners in their noble mission of caring for the local patients. With strong growth plans, this is investing is a new multiproduct general formulation plant which should be the biggest in Algeria with an area of 17,500 sqm. The plant will be first one to manufacture Soft gelatin capsules in the country. Apart from the Oral solid dosage forms, they have high volume lines coming up to manufacture liquid oral in bottles and stick packs and ointment line. Pharma Access is executing this project on a Turnkey basis (excluding filling & packing lines). The project in ongoing in Algiers and is expected to be completed by November 2020. ...
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On May 13, 1986, the Drug Enforcement Administration (DEA) issued a Final Rule and Statement of Policy authorizing the rescheduling of synthetic dronabinol in sesame oil and encapsulated in soft gelatin capsules from Schedule I to Schedule II (DEA 51 FR 17476-78). This permitted medical use of Marinol, albeit with the severe restrictions associated with Schedule II status.[13] For instance, refills of Marinol prescriptions were not permitted. At its 10th meeting, on April 29, 1991, the Commission on Narcotic Drugs, in accordance with article 2, paragraphs 5 and 6, of the Convention on Psychotropic Substances, decided that Δ⁹-tetrahydrocannabinol (also referred to as Δ⁹-THC) and its stereochemical variants should be transferred from Schedule I to Schedule II of that Convention. This released Marinol from the restrictions imposed by Article 7 of the Convention (See also United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances).[citation needed]. An ...
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Novel oil-filled microcapsules were prepared by introducing a phase separation method using ethyl cellulose as a shell-forming containing rapeseed oil. The prepared oil-filled microcapsules were evaluated by optical microscopy, scanning electron microscopy and particle size analysis. Results showed that spherical microcapsules with a diameter of 10 to 45 μm and a rough porous shell were obtained. Carboxylated styrene/butadiene copolymer latex films containing various levels of these microcapsules were subjected to various levels of pre-elongation and their tensile properties were examined. The addition of oil-filled microcapsules resulted in a significant improvement in the modulus, strain-to-break, and toughness of the films. The self-healing mechanism of latex films was examined through the colorimetric measurements of the release of dye-containing following the pre-elongation of the samples. These measurements confirmed that pre-elongation of samples resulted in the release of oil within the ...
This study will compare the pharmacokinetics and tolerability of rabeprazole granules when administered with yoghurt, applesauce, ready-to-feed infant formula
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Disclosed is a microcapsule composition for inhibiting an ethylene response in plants, which comprises a plurality of microcapsules, each including an agent for blocking an ethylene binding site in plants in an oil droplet, and a coating encapsulating the oil droplet and the agent for blocking the ethylene binding site in plants. A method for preparing microcapsules of an agent for blocking the ethylene binding site in plants, and a method for inhibiting an ethylene response in plants are also disclosed.
Microencapsulation of recombinant cells is a novel promising approach to tumor therapy in which therapeutic protein is sustainable and long-term delivered by microencapsulated cells. The semi-permeable membrane of microcapsule can protect cell from hosts immune rejection, increase the chemical stability of therapeutic protein and circumvent the problems of toxicity, limited half-lives and variation in circulating levels. Endostatin, a potent and specific angiogenesis inhibitor, could suppress the growth of primary and metastatic lesions in multiple murine tumor models. In this paper, APA microcapsules with high strength kept intact over 35 days and recombinant CHO cells kept the rapid proliferation viability and the continuous endostatin-expression function. The study of tumor treatment showed that the implantation of microencapsulated recombinant CHO cells decreased the neovascularization of tumor tissue by 59.4% and inhibited the B16 melanoma growth by 77.4%. Twenty days after tumor cell ...
SOARES DE OLIVEIRA CARVALHO, Anna Paula; KIMI UEHARA, Sofia; FIRMINO NOGUERIA NETTO, José and ROSA, Glorimar. Hypocaloric diet associated with the consumption of jam enriched with microencapsulated fish oil decreases insulin resistance. Nutr. Hosp. [online]. 2014, vol.29, n.5, pp.1103-1108. ISSN 1699-5198. http://dx.doi.org/10.3305/nh.2014.29.5.6654.. Background: The metabolic syndrome is related to the increase in cardiovascular diseases. Polyunsaturated fatty acids from fish oil help in reducing cardiovascular risk factors and are natural bindings of PPARy2. Objective: To evaluate the impact of hypocaloric diet associated with microencapsulated fish oil supplementation in women with metabolic syndrome. Methods: We conducted a randomized, single-blind and placebo-controlled clinical trial with adult women who presented metabolic syndrome (n = 30) for 90 days. The volunteers were divided into two groups: placebo group (n = 15) and microencapsulated fish oil group (n = 15) (3 g/day of ...
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TY - JOUR. T1 - Distribution of PEG-coated hollow polyelectrolyte microcapsules after introduction into the circulatory system and muscles of zebrafish. AU - Borvinskaya, Ekaterina. AU - Gurkov, Anton. AU - Shchapova, Ekaterina. AU - Baduev, Boris. AU - Meglinski, Igor. AU - Timofeyev, Maxim. N1 - This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. PY - 2018/1/5. Y1 - 2018/1/5. N2 - The use of polyelectrolyte multilayer microcapsules as carriers for fluorescent molecular probes is a prospective technique for monitoring the physiological characteristics of animal vasculature and interstitial environment in vivo. Polyelectrolyte microcapsules have many features that favor their use as implantable carriers of optical sensors, but little information is available on their ...
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Capsugel is the first hard capsule manufacturer to receive the EXCiPACT™ certification. The certification provides independent validation that Capsugels European manufacturing sites maintain excipient Good Manufacturing Practices (GMPs) and comply with current European Union regulations in the manufacturing of empty, two-piece hard capsules.This webinar covers the regulatory background regarding the EU Directive on Falsified Medicines, the process and scope of the EXCiPACT™ excipient GMP certification, and the related benefits to companies marketing pharmaceutical products in the European Union.
"About Health Capsules," GoComics website. Accessed Nov. 24, 2018. Health Capsules at GoComics Health Capsules section of Bron ... Health Capsules is currently produced by Bron Smith. Health Capsules was originally produced by Dr. Michael A. Petti and ... GoComics characterizes Health Capsules this way: Health Capsules was begun as an effort to educate people about common health ... Health Capsules is read by millions in The Times of India and other newspapers across America and abroad. It is translated into ...
Officially, three prototypes of the capsule were created. The Fénix 1 had a larger diameter than the other two capsules and was ... Images related to the Fénix class rescue capsule The fifth rescuer, Patricio Sepúlveda, is in the rescue capsule and is being ... Fénix-2 capsule on display in front of La Moneda presidential palace in Santiago Fénix-2 capsule on display in Santiago in ... The capsule will be recognized by the whole world for decades to come and would be a major tourist attraction for any science ...
The second capsule is placed ten feet north of the first capsule. The capsules are filled with physical objects of that time ... Time Capsule I weighs about 800 pounds (360 kg), while Time Capsule II weighs about 400 pounds (180 kg). Time Capsule I was ... An exact duplicate of the capsule's articles resides at the Heinz History Center beside a replica capsule of Time Capsule I. ... Time Capsule I was created for the 1939 New York World's Fair and Time Capsule II was created for the 1964 New York World's ...
The National Lacrosse League (NLL) is a professional men's indoor lacrosse league in North America. It currently has 15 teams; 5 in Canada and 10 in the United States. Unlike the Canadian box lacrosse leagues which play in the summer, the NLL plays its games in the winter and spring, from December to June. Each year, the playoff teams battle for the Champion's Cup. A complete summary of NLL teams' performance is below. * Buff McCready only coached the Bandits for the first three games. * The Knighthawks had the overall top seed in the playoffs, but were unable to host the Championship game due to a scheduling conflict at the Blue Cross Arena.. "The Complete History of the NLL". National League Lacrosse. Retrieved December 5, 2017. "Arizona To Host Championship Game". NLL.com. April 30, 2007. Archived from the original on April 16, 2008. Retrieved 2007-04-30. (Wikipedia articles in need of updating from April 2017, All Wikipedia articles in need of updating, National Lacrosse League teams ...
Yahoo Time Capsule, open as Yahoo.com 20th anniversary KEO Lansing Time Capsule Dates of opening of already opened capsules. ... Westinghouse Time Capsules Wikimedia Commons has media related to Time capsules. Look up time capsule in Wiktionary, the free ... this capsule was planted to replace the 1977 capsule opened the same year. A time capsule is also present on the grounds of ... Within the time capsule was about two feet of water destroying most paper artifacts in the capsule. A miner's helmet and a pair ...
"1888 Time Capsule Is Found in Wall Street Building; '88 TIME CAPSULE FOUND IN WALLST". The New York Times. 12 July 1957. ... Durham Magazine, 17 April 2017 Wikimedia Commons has media related to Time capsules. Ten most-wanted time capsules, Ogelthorpe ... The following is a timeline of time capsules that are either scheduled to be installed, to be opened or have already been ... "Cápsula Bicentenario quedó enterrada por un siglo en Plaza de Armas" [Bicentennial Capsule was buried for one century in Plaza ...
Look up capsule in Wiktionary, the free dictionary. Capsule may refer to: Articular capsule (joint capsule), an envelope ... fibrous layer surrounding the kidney Capsules of the brain External capsule Extreme capsule Internal capsule Bacterial capsule ... a passenger compartment Capsule (fruit), or seed capsule, a type of dry fruit like the poppy, iris or foxglove Capsule ( ... a type of artificial neural network Capsule review, short critique Space capsule, a type of crewed spacecraft Time capsule, a ...
"Capsule Wardrobe". Archived from the original on 4 January 2012. Retrieved 8 April 2012. "How to build the perfect capsule ... "Capsule Wardrobe list". sewguide.com. Trotter, Louise (1 February 2009). "How to build a capsule wardrobe". London: The ... "How to build a capsule wardrobe around three colours". Retrieved 8 April 2012. Vears, Amy. "The perfect capsule wardrobe: ... The use of "capsule" to mean "small and compact" was a distinctly American use of the word that surfaced in 1938 according to ...
The capsule itself appears as a thin white sheet of white matter. The external capsule is a route for cholinergic fibers from ... But the external capsule eventually joins the internal capsule around the lentiform nucleus. Superficial dissection of brain- ... External capsule External capsule Ventricles of brain and basal ganglia. Superior view. Horizontal section. Deep dissection. ... The putamen separates the external capsule from the internal capsule medially and the claustrum separates it from the extreme ...
... may refer to: In the Yu-Gi-Oh! franchise: Capsule Monster Chess or CapMon, a fictional board game that Mokuba ... whose working title was Capsule Monsters in 1990 This disambiguation page lists articles associated with the title Capsule ... franchise produced by 4Kids Entertainment Capsule Monsters, a power used by the titular character in Ultra Seven Pokémon Red ... Kaiba plays and forces Yugi Mutou to play twice Yu-Gi-Oh!! Capsule Monsters, a twelve-episode mini-series in the Yu-Gi-Oh!! ...
A launch capsule is a device used to propel a submarine-launched missile to the ocean surface. Upon reaching the ocean surface ... the launch capsule is jettisoned, and the missile continues its journey, propelled by its booster motor. v t e (Articles with ...
Another study assessed the efficacy of Yizhi capsule in treating senile dementia. The results showed that Yizhi capsule could ... Xu, H; Shao, N; Cui, D; Hu, Z; Bi, J; Jiang, Q; Li, N (March 2000). "A clinical study of yi zhi capsules in prevention of ... Yizhi capsule (YZC) is a type of traditional Chinese medicine (TCM) developed for treating vascular dementia. A study in rats ... Moreover, Yizhi capsule improved cerebral blood flow, brain electrical activity monitoring (BEAM) and hemorheological indexes ...
... uses a small vitamin-sized wireless camera to capture images of a patient's digestive tract. The capsule is ... Capsule endoscopy is considered to be a very safe method for gastrointestinal tract examination. The capsule is usually ... A transmitted radio-frequency signal emitted by some capsules can be used to accurately estimate the location of the capsule ... The rate of capsule retention varies by the indication for the procedure, with the highest rate seen with known Crohn's disease ...
1966 About Capsules SpaceX Building Reusable Crew Capsule Gemini 11 Space Capsule Archived 2014-10-04 at the Wayback Machine ( ... A space capsule is an often-crewed spacecraft that uses a blunt-body reentry capsule to reenter the Earth's atmosphere without ... The United States launched a total of two crewed suborbital Mercury capsules and four crewed orbital capsules, with the longest ... Current examples of crewed space capsules include Soyuz, Shenzhou, and Dragon 2. Examples of new crew capsules currently in ...
... the capsule appears as a clear halo around the bacterium as the ink can't penetrate the capsule.: 87 Maneval's capsule stain: ... When viewed, bacterial capsules appear as a bright halo around the cell on a dark background. The capsule is considered a ... Capsules also help cells adhere to surfaces. As a group where the capsule is present they are known as polysaccharide ... A capsule-specific antibody may be required for phagocytosis to occur. Capsules also contain water which protects the bacteria ...
A capsule (from Latin capsula, "small box or chest"), or stadium of revolution, is a basic three-dimensional geometric shape ... A capsule is the three-dimensional shape obtained by revolving the two-dimensional stadium around the line of symmetry that ... The volume V {\displaystyle V} of a capsule is calculated by adding the volume of a ball of radius r {\displaystyle r} (that ... A capsule can be equivalently described as the Minkowski sum of a ball of radius r {\displaystyle r} with a line segment of ...
A capsule review or mini review is a form of appraisal, usually associated with journalism, that offers a relatively short ... Leonard Maltin's Movie Guide is a well known publication that includes thousands of capsule movie reviews by prolific film ... "The Short Summary and Capsule Review". Critical Reading and Writing. Longman. 1983. Page 375 et seq. Google Books The Word, ... writer Leonard Maltin, including the world's shortest capsule review according to the Guinness Book of World Records, a 2 out ...
In 2013, Capsule released Capsule for Mobile on the App Store and Play Store. In 2018, Capsule released a Teams plan. The ... Capsule was released in 2009 originally under the name Javelin, before being renamed to Capsule in 2010. In 2011, Capsule ... "Capsule - Apps on Google Play". play.google.com. Retrieved 2018-06-11. "Capsule Adds Teams Plan to Its CRM". Retrieved 2019-05- ... Capsule is a customer relationship management (CRM) software-as-a-service web application and mobile app developed by Zestia, a ...
... (/təˈnoʊn/), also known as the Tenon capsule, fascial sheath of the eyeball (Latin: vagina bulbi) or the fascia ... The capsule is perforated behind by the ciliary vessels and nerves and fuses with the sheath of the optic nerve and with the ... Tenon's capsule is perforated by the tendons of the ocular muscles and is reflected backward on each as a tubular sheath. The ... Tenon's capsule may be affected by a disease called idiopathic orbital inflammation, a condition of unknown etiology that is ...
... IV and Cold Capsule V were extended release oral capsules (pill) used to control cold symptoms. Both products ... but Cold Capsule IV contained 12 mg chlorpheniramine maleate while Cold Capsule V had 8 mg . They was manufactured by Graham DM ... Both Cold Capsule products are now Discontinued. http://drugpatentwatch.com/p/tradename/COLD+CAPSULE+IV, "Profile for Tradename ... COLD CAPSULE IV", DrugPatentWatch.com https://www.fda.gov/cder/drug/infopage/ppa/advisory.htm Food and Drug Administration ...
... may refer to: Fibrous capsule of Glisson Fibrous membrane of articular capsule This disambiguation page lists ... articles associated with the title Fibrous capsule. If an internal link led you here, you may wish to change the link to point ...
The extreme capsule is separated from the external capsule by the claustrum, and the extreme capsule separates the claustrum ... Extreme capsule Extreme capsule Jones, Jeremy. "Extreme capsule , Radiology Reference Article , Radiopaedia.org". Radiopaedia. ... the extreme capsule is the outermost from the external capsule and the inner internal capsule. It is most easily visible in a ... The extreme capsule (Latin: capsula extrema) is a series of nerve tracts between the claustrum and the insular cortex. It is ...
Sharing within a capsule is limited to everyone within the capsule only. With Capsule your every connection is defined by the " ... It's really easy to send your party photos straight to the capsule for everyone in the capsule to see". Capsule operates as a ... "Capsule Wants To Be Your One Stop Shop For (Private) Events". "Try Free Group Texting And Events With Capsule". Johnson, Kelly ... All members of the capsule are allowed to view the photos shared by a member of the capsule. It also has a mode that allows ...
... (or the Bowman capsule, capsula glomeruli, or glomerular capsule) is a cup-like sac at the beginning of the ... Fluids from blood in the glomerulus are collected in the Bowman's capsule. Outside the capsule, there are two "poles": The ... Inside the capsule, the layers are as follows, from outside to inside:[citation needed] Parietal layer-A single layer of simple ... However, thorough microscopical anatomy of kidney including the nephronic capsule was first described by Ukrainian surgeon and ...
"Karappo Capsule" (からっぽカプセル, lit. Empty Capsule) is Japanese voice actress and singer Maaya Uchida's 3rd single, released on ...
Capsule (カプセル, Kapuseru, stylized as CAPSULE since autumn 2013 and previously as capsule) is a Japanese electronica band ... "On 23 October, 2013, the new album "CAPS LOCK" will be released!". Capsule-official.com (in Japanese). "Capsule - Wave Runner ... Wikimedia Commons has media related to Capsule (band). capsule Official website Facebook (CS1 Japanese-language sources (ja), ... Capsule's first new song in six years, Hikari no Disco, was teased in April 2021 and was released on June 3, 2021. On the 25th ...
Polar capsules are structures found in the valves of Myxosporean parasites, which contain the polar filament. The polar capsule ... The mouth of the capsule is covered with a cap-like structure. This structure may function as a stopper, its digestion in the ... Firstly, that the hydrostatic pressure in the polar capsule pushes the filament out, rather like the cnidocyst of jellyfish. ...
Articular capsule of the humerus Articular capsule of the knee joint Atlanto-axial joint Capsule of atlantooccipital ... In anatomy, a joint capsule or articular capsule is an envelope surrounding a synovial joint. Each joint capsule has two parts ... Each capsule consists of two layers or membranes: an outer (fibrous membrane, fibrous stratum) composed of avascular white ... The fibrous membrane of the joint capsule is attached to the whole circumference of the articular end of each bone entering ...
Wikimedia Commons has media related to Internal capsule. Stained brain slice images which include the "internal capsule" at the ... The internal capsule consists of three parts and is V-shaped when cut horizontally, in a transverse plane. the bend in the V is ... The internal capsule is a white matter structure situated in the inferomedial part of each cerebral hemisphere of the brain. It ... The internal capsule contains both ascending and descending axons, going to and coming from the cerebral cortex. It also ...
The adipose capsule is sometimes included in the structure of the renal capsule. It provides some protection from trauma and ... The renal capsule surrounds the functional tissue of the kidney, and is itself surrounded by a fatty adipose capsule, fascia, ... Sometimes the adipose capsule of the kidney also known as the perirenal fat, is regarded as a part of the renal capsule. Renal ... renal medulla renal cortex renal capsule adipose capsule of kidney (or perirenal fat, or perinephric fat) renal fascia ...
Loperamide hydrochloride capsules USP, 2 mg are available as:. A light brown opaque body and dark brown opaque capsule, ... The recommended initial dose is 4 mg (two capsules) followed by 2 mg (one capsule) after each unformed stool until diarrhea is ... one capsule) after each unformed stool. The maximum daily dose is 16 mg (eight capsules). Clinical improvement is usually ... LOPERAMIDE HYDROCHLORIDE capsule. To receive this label RSS feed. Copy the URL below and paste it into your RSS Reader ...
Order Macu-Save once a day easy to swallow food supplement capsules from LloydsPharmacy with free delivery or Click & Collect, ... Take one capsule with water and food everyday.. ((accordion-separator)) Ingredients. 10mg Meso-Zeaxanthin, 10mg Lutein and 2mg ... Features of Macu-Save once a day capsules. *Gluten-free, yeast-free and lactose-free. ...
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This sheet explains how to open the capsules and mix with water, milk, chocolate milk or food for infants and children. ... Instructions for Opening and Mixing Tecovirimat Capsules. ...
Capsule enteroscopy; Wireless capsule endoscopy; Video capsule endoscopy (VCE); Small bowel capsule endoscopy (SBCE) ... Another way to look inside is to put a camera in a capsule (capsule endoscopy). This capsule includes one or two tiny cameras, ... Flush the capsule down the toilet.. *If you do not see the capsule in the toilet within two weeks of swallowing it, tell your ... Each capsule is used only once.. *The health care provider may ask you to lie down or sit up while swallowing the capsule. ...
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Autor desconhecido (‎2011)‎. Dabigatran etexilate mesylate capsules: storage and handling. https://apps.who.int/iris/handle/ ...
How effective are second-generation colon capsule endoscopes at evaluating the severity of mucosal inflammation in patients ... Colon capsule endoscopy (CCE) was first reported in 2006.[5] CCE has been applied mainly for colorectal cancer screening.[5-13] ... Background and Aim Colon capsule endoscopy has already been used for colon visualization and detection of polyps but its ... A CCE procedure requires extensive, multi-step preparation[9] for colon cleansing and the capsule booster. ...
Patient information for FORCEVAL CAPSULES Including dosage instructions and possible side effects. ... What Forceval Capsules are and what they are taken for. Check before you take Forceval Capsules. How to take Forceval Capsules ... What Forceval Capsules look like and contents of the pack. Forceval Capsules are brown and maroon, soft gelatin capsules ... Forceval Capsules contain iron, an overdose could be fatal in children. under 12 years.. 3. How to take Forceval Capsules. 6. ...
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Children 6 years to 12 years of age: take 25 mg (1 capsule) every 4 to 6 hours; not more than 6 capsules in 24 hours.. Children ... Adults and children 12 years and over: take 25 to 50 mg (1 to 2 capsule) every 4 to 6 hours; not more than 12 capsules in 24 ... DIPHENHYDRAMINE - diphenhydramine hydrochloride capsule H.J. Harkins Company, Inc.. Disclaimer: Most OTC drugs are not reviewed ...
Inovance Ysonut Noctivance 30 capsules Jet lag, sleep onset, sleep • SLEEP PROBLEMS HAVE. • ME I ORDER TO MAKE A TRIP TO CHANGE ... Inovance Ysonut Noctivance 30 capsules. Inovance Ysonut Noctivance 30 capsules Jet lag, sleep onset, sleep • SLEEP PROBLEMS ... Inovance Ysonut Noctivance 30 capsules Jet lag, sleep onset, sleep • SLEEP PROBLEMS HAVE. • ME I ORDER TO MAKE A TRIP TO CHANGE ... Instructions for use 1 capsule per day 1 hour before bedtime or as directed by a health professional. - Composition of 1 tablet ...
CurcuminX4000 Now with added Fenugreek 180 Veggie Capsules - Now Available in an Environmentally Friendly Refill ... 3 Capsules. Serving Per Container. 60. Directions. Take 3 capsules per day with food or as directed by a healthcare ... Each capsule of CurcuminX4000® contains 200mg of this highly effective formulation. A recent study showed the body was able to ... CurcuminX4000 Now with added Fenugreek 180 Veggie Capsules - Now Available in an Environmentally Friendly Refill Pouch. ...
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Capsules: Capsules are another convenient form of CBD. They usually come in the form of pills or softgels infused with CBD. ... 3 of the top CBD gel capsules for people to consider. Medically reviewed by Eloise Theisen, RN, MSN, AGPCNP-BC ... Read on to discover what CBD gel capsules are, as well as their potential health risks and benefits. We also list some CBD ... The capsules contain bovine gelatin, so they are not suitable for vegans or vegetarians. ...
Ever get the giggles from seeing a kid on a leash?! As funny as it might look, that leash protects little ones from getting lost or, even worse, kidnapped. Perhaps this wearable solution is precisely what we need to prevent these worst case scenarios. Its called Ora and the designers describe it as a smart
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... our favorite was this Rolling Stones traveling capsule by Slovakia-based Nice ... rolling-stone-capsule-1. 1 of 10 Earlier this year the residency program at the Andes Sprouts Society issued a call for housing ... rolling-stone-capsule-2. 2 of 10 Earlier this year the residency program at the Andes Sprouts Society issued a call for housing ... rolling-stone-capsule-3. 3 of 10 Earlier this year the residency program at the Andes Sprouts Society issued a call for housing ...
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BENTON NOTES: Tigers rallied from a 12-point deficit in final 5 minutes to defeat Fair Park … Freshman QB Garrett Hable came off the bench and threw three TD passes, two to Tyler Stephens and the game-winner to TJ ...
These are empty size 00 kosher gelatin capsules. They measure 8.53mm across and 23.30mm long. They hold 0.95mL, which typically ... These are empty size 00 kosher gelatin capsules. They measure 8.53mm across and 23.30mm long. They hold 0.95mL, which typically ...
Decrease quantity for Schizandra Fruit 100 capsules Increase quantity for Schizandra Fruit 100 capsules ... Take 2 capsules twice daily, preferably with food.. Serving Size: 2 Capsules. Amount Per Serving. Calories ... 5. Schizandra ...
Browse Classroom Capsules and Notes. You can filter the list below by selecting a subject category from the drop-down list ... Home » Programs » Faculty and Departments » Browse Classroom Capsules and Notes. ...
Reusable Capsule. The Starliner uses a proven parachute and airbag system to land on ground, which allows the capsule to be ... Helping to design a space capsule would be amazing, but Kavya Manyapu is designing a space capsule she might ride in one day. ... CST-100: Next American Space Capsule September 16, 2014 in Space. NASA awards Boeing $4.2 billion to build and fly the United ... The Starliner is designed for land-based returns rather than water returns, a first for a space capsule built in the United ...
The meaning of OPTIC CAPSULE is either of a pair of cartilaginous capsules that develop around the eyes of elasmobranch fishes ... either of a pair of cartilaginous capsules that develop around the eyes of elasmobranch fishes and of embryos of higher ... "Optic capsule." Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/optic%20capsule. ...
  • FDA laboratory analysis confirmed that Wild Sexx Capsules contains sildenafil and tadalafil, the active ingredients in the FDA-approved prescription drugs Viagra and Cialis, respectively, used to treat erectile dysfunction (ED). These undeclared ingredients may interact with nitrates found in some prescription drugs such as nitroglycerin and may lower blood pressure to dangerous levels. (fda.gov)
  • Other Ingredients: Cellulose (Capsule), Carob Powder, Magnesium Stearate (Vegetable Source). (wholefoodsmarket.com)
  • Do not take the tacrolimus capsule, if you are allergic to it or any of its ingredients. (ikrispharmanetwork.com)
  • Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023. (bvsalud.org)
  • Capsule endoscope will have a slippery coating, so it is easier to swallow. (medlineplus.gov)
  • Swallow with water, or split the capsule and sprinkle over food. (boots.com)
  • Swallow the capsules whole. (clevelandclinic.org)
  • Our B-Complex contains a base level of all B vitamins including 50 mg of thiamin available in a small, easy to swallow capsule. (celebratevitamins.com)
  • With this product there isn't much to say other than it isn't as big as some other type of capsules so easy to swallow. (celebratevitamins.com)
  • 2 capsules each containing 0.25g dry weight of kawakawa to be consumed daily for 1 week + 2 capsules each containing 0.25g cellulose (metabolically inert) as a placebo to be consumed daily for 1 week. (who.int)
  • Qyresearchreports include new market research report "Global Coffee Capsules Sales Market Report 2017" to its huge collection of research reports. (openpr.com)
  • The CST-100 capsule is being designed to transport up to seven crew members to the International Space Station and other low-Earth orbit locations by 2017, Aitech said May 5 . (executivebiz.com)
  • Boeing will assemble three CST-100 units at its Florida facility under the program"™s Commercial Crew Transportation Capability phase and will subject the capsule to a pad-abort trial prior to its 2017 crewed flight. (executivebiz.com)
  • Cette étude documentaire, analyse les données des patients diagnostiqués et traités pour tuberculose de 2007 à 2017 en RDC. (bvsalud.org)
  • Le taux d'accroissement au cours de cette décade était de 28,95%, soit de 66099 en 2007 à 93767 en 2017 pour les NP TP+. (bvsalud.org)
  • Motherlove's best-selling more milk plus alcohol free liquid concentrate in vegetarian capsules. (mothering.com)
  • The product image of NOW Foods - Tribulus 500mg (Tribulus Terrestris Extract) - 100 Capsules shown on this page may differ from actual size and flavor, or due to packaging update. (vitacart.com)
  • The Starliner is a next-generation space capsule that will take people to and from low-Earth orbit. (boeing.com)
  • The US Food and Drug Administration's (FDA's) Anesthetic and Analgesic Drug Advisory Committee of independent experts voted 11 to 2, with 1 abstention, to recommended against approval of hydrocodone bitartrate extended-release capsules ( Zohydro ER , Zogenix), a formulation of hydrocodone without acetaminophen for the treatment of moderate to severe chronic pain. (medscape.com)
  • Each capsule of CurcuminX4000® contains 200mg of this highly effective formulation. (thepowermall.com)
  • For a custom formulation, minimum quantities vary between 100.000 and 300.000 capsules depending on the product. (privatelabelnutrition.de)
  • On May 26, the FDA approved a capsule formulation of paricalcitol (Zemplar, made by Abbott Laboratories) for the prevention and treatment of secondary hyperparathyroidism (SHPT) in patients with stage III and IV chronic kidney disease (CKD), prior to the need for dialysis or renal transplantation. (medscape.com)
  • A malfunction during a drop test over Nevada last month for SpaceX's Crew Dragon program has engineers re-examining the crew capsule's parachutes, and Boeing has also encountered parachute failures during testing for its commercial crew capsule, a senior NASA official confirmed Wednesday. (spaceflightnow.com)
  • NASA officials have long identified parachutes as a concern for SpaceX and Boeing crew capsules, which are in the final stages of development before they carry astronauts into orbit for the first time. (spaceflightnow.com)
  • After completing their test programs, the SpaceX and Boeing capsules will begin ferrying astronauts to and from the International Space Station, ending NASA's sole reliance on Russian Soyuz spacecraft for crew transportation. (spaceflightnow.com)
  • The capsules themselves had customizable lights and an inviting decor. (booking.com)
  • Suggested Use As a dietary supplement take three capsules once daily. (vitaminlife.com)
  • As an herbal dietary supplement, take 1 Tribulus capsule, 1-3 times daily as needed prior to meals. (vitacart.com)
  • Hydrocodone bitartrate extended-release capsules were evaluated in more than 1100 patients with chronic pain in a phase 3 efficacy study and an open-label phase 3 safety study. (medscape.com)
  • Creon is taken orally in capsule form, and dose is based on the patient's age and body weight. (rxlist.com)
  • The main function is to add calls to Capsule directly from your mobile phone. (mobiletoones.com)
  • Discover the beautiful taste of the 100% Arabica illy blend, now available in aluminium capsules compatible with Nespresso®* coffee machines . (illy.com)
  • illy aluminium capsules are designed specifically for use with Nespresso®* coffee machines except models U®*, Umilk®*, Expert®*, Expert&Milk®*, Prodigio®* and Prodigio&Milk®* purchased after July 25, 2016. (illy.com)
  • What's Inside a Nespresso Capsule? (danderma.co)
  • Ever wondered how the contents of the Nespresso capsule brings you joy every morning by producing your coffee fix? (danderma.co)
  • I had very few limited edition Dark Chocolate Nespresso capsules left in my possesion and I was being very stingy with them. (danderma.co)
  • 2 strength combinations of Glucosamine / Chondroitin Capsule are available. (wedgewoodpharmacy.com)
  • Extra Strength Turmeric Curcumin from Webber Naturalscontains 500 mg of turmeric extract per capsule, the equivalent to 12,500 mg of raw herb. (vitamart.ca)
  • The term 'time capsule' was coined by Westinghouse's PR man George Edward Pendray.Time capsules are all about posterity and sending messages to future generations. (good.is)
  • Less ambitious personal time capsules, not scientific or multi-millennial, can be done on a smaller scale and still reach across time to bring later generations an important glimpse of the past. (good.is)
  • Buried time capsules often get lost. (good.is)
  • It seems all those time capsules are now at the new Blue Peter HQ in Salford . (londonist.com)
  • The Los Angeles Times reports that "Bayer Healthcare is recalling 100,000 packages of Alka-Seltzer cold capsules because some do not properly display warning information about drowsiness. (rhllaw.com)
  • Take 2 capsules twice daily, preferably with food. (bayho.com)
  • 10-23-2015] The Food and Drug Administration (FDA) is advising consumers not to purchase or use Wild Sexx Capsules, a product promoted for sexual enhancement. (fda.gov)
  • Shopping for the best deal on Vitamins & Nutrition, Kyolic, Acne, Capsules Vitamins & Nutrition - Read product reviews, compare prices and store ratings. (pricegrabber.com)
  • Also in this section is profiling of a number of companies currently operating in the global Coffee Capsules market, providing insights on business overview, headquarters, product portfolio, and regional presence. (openpr.com)
  • Each capsule is standardized to 95% curcuminoids, one of turmeric's most active constituents, making this our highest potency turmeric product. (vitamart.ca)
  • Lock in a great price for De Bedstee Boutique Capsules - rated 8 by recent guests! (booking.com)
  • The capsule is the size of a large vitamin pill, about an inch (2.5 centimeters) long and less than ½ inch (1.3 centimeters) wide. (medlineplus.gov)
  • Choose items that will explain this present moment to whoever opens the capsule in the future. (good.is)
  • Capsules are being released in perpetual fashion moving forwards in order to fulfill the market appetite for tradable products which generate continuous yield. (comb.financial)
  • This sheet explains how to open the capsules and mix with water, milk, chocolate milk or food for infants and children. (cdc.gov)
  • Here are my reasons for not including various shows on the list, and feel free to comment with any shows you think I unfairly left out of the time capsule for one reason or another. (cultural-learnings.com)
  • The capsules are of vegetarian source and free of GMOs, yeast, and gluten. (healthyplanetcanada.com)
  • CST-100 Starliner Test Article domes mated into full capsule for first time at Kennedy Space Center. (boeing.com)
  • A stickler for detail, Sweet even made sure that "Time Capsule" came full circle from "Girlfriend," his 1991 breakthrough modern-rock LP. A pre-"Dobie Gillis" photo of actress Tuesday Weld graced the cover of "Girlfriend. (pauseandplay.com)
  • Take one capsule with water and food everyday. (lloydspharmacy.com)
  • Part gypsy wagon, part RV trailer, and all aerodynamic eco-capsule, this mobile modern living structure is compact, built from environmentally friendly materials, and self-sufficient in terms of energy, water and waste. (inhabitat.com)
  • Tacrolimus capsules should be swallowed whole with water. (ikrispharmanetwork.com)
  • As capsules tap onto zCOMB's revenue share capability, the two year lock needs to be refreshed periodically in order to maintain the capsule's high yield. (comb.financial)
  • Take 2 capsules three times daily between meals or as needed. (youngliving.com)