Fungemia: The presence of fungi circulating in the blood. Opportunistic fungal sepsis is seen most often in immunosuppressed patients with severe neutropenia or in postoperative patients with intravenous catheters and usually follows prolonged antibiotic therapy.Candida tropicalis: A species of MITOSPORIC FUNGI that is a major cause of SEPTICEMIA and disseminated CANDIDIASIS, especially in patients with LYMPHOMA; LEUKEMIA; and DIABETES MELLITUS. It is also found as part of the normal human mucocutaneous flora.Candida: A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. It is commonly part of the normal flora of the skin, mouth, intestinal tract, and vagina, but can cause a variety of infections, including CANDIDIASIS; ONYCHOMYCOSIS; vulvovaginal candidiasis (CANDIDIASIS, VULVOVAGINAL), and thrush (see CANDIDIASIS, ORAL). (From Dorland, 28th ed)Candidiasis: Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)Candida albicans: A unicellular budding fungus which is the principal pathogenic species causing CANDIDIASIS (moniliasis).Antifungal Agents: Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.Alkanes: The generic name for the group of aliphatic hydrocarbons Cn-H2n+2. They are denoted by the suffix -ane. (Grant & Hackh's Chemical Dictionary, 5th ed)Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.Drug Resistance, Fungal: The ability of fungi to resist or to become tolerant to chemotherapeutic agents, antifungal agents, or antibiotics. This resistance may be acquired through gene mutation.MycosesTrichosporon: A mitosporic fungal genus causing opportunistic infections, endocarditis, fungemia, a hypersensitivity pneumonitis (see TRICHOSPORONOSIS) and white PIEDRA.Mycology: The study of the structure, growth, function, genetics, and reproduction of fungi, and MYCOSES.Candida glabrata: A species of MITOSPORIC FUNGI commonly found on the body surface. It causes opportunistic infections especially in immunocompromised patients.Mycological Typing Techniques: Procedures for identifying types and strains of fungi.Fungi: A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies.Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.Candidemia: A form of invasive candidiasis where species of CANDIDA are present in the blood.Carnitine O-Acetyltransferase: An enzyme that catalyzes the formation of O-acetylcarnitine from acetyl-CoA plus carnitine. EC 2.3.1.7.Microbiological Techniques: Techniques used in microbiology.Echinocandins: Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS.Microbodies: Electron-dense cytoplasmic particles bounded by a single membrane, such as PEROXISOMES; GLYOXYSOMES; and glycosomes.Xylitol: A five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.DNA, Fungal: Deoxyribonucleic acid that makes up the genetic material of fungi.Blood: The body fluid that circulates in the vascular system (BLOOD VESSELS). Whole blood includes PLASMA and BLOOD CELLS.Microbial Sensitivity Tests: Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).Acetyl-CoA C-Acyltransferase: Enzyme that catalyzes the final step of fatty acid oxidation in which ACETYL COA is released and the CoA ester of a fatty acid two carbons shorter is formed.Azoles: Five membered rings containing a NITROGEN atom.Cryptococcus: A mitosporic Tremellales fungal genus whose species usually have a capsule and do not form pseudomycellium. Teleomorphs include Filobasidiella and Fidobasidium.Culture Media: Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.Acetyl-CoA C-Acetyltransferase: An enzyme that catalyzes the formation of acetoacetyl-CoA from two molecules of ACETYL COA. Some enzymes called thiolase or thiolase-I have referred to this activity or to the activity of ACETYL-COA C-ACYLTRANSFERASE.Dermatomycoses: Superficial infections of the skin or its appendages by any of various fungi.Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.Rhodotorula: A red yeast-like mitosporic fungal genus generally regarded as nonpathogenic. It is cultured from numerous sources in human patients.XyloseCatheterization, Central Venous: Placement of an intravenous CATHETER in the subclavian, jugular, or other central vein.Yeasts: A general term for single-celled rounded fungi that reproduce by budding. Brewers' and bakers' yeasts are SACCHAROMYCES CEREVISIAE; therapeutic dried yeast is YEAST, DRIED.Exophiala: A normally saprophytic mitosporic Chaetothyriales fungal genus. Infections in humans include PHAEOHYPHOMYCOSIS; and PERITONITIS.. Exophiala jeanselmei (previously Phialophora jeanselmei) is an etiological agent of MYCETOMA.Immunocompromised Host: A human or animal whose immunologic mechanism is deficient because of an immunodeficiency disorder or other disease or as the result of the administration of immunosuppressive drugs or radiation.Peptones: Derived proteins or mixtures of cleavage products produced by the partial hydrolysis of a native protein either by an acid or by an enzyme. Peptones are readily soluble in water, and are not precipitable by heat, by alkalis, or by saturation with ammonium sulfate. (Dorland, 28th ed)Lipopeptides: Compounds consisting of a short peptide chain conjugated with an acyl chain.Dentures: An appliance used as an artificial or prosthetic replacement for missing teeth and adjacent tissues. It does not include CROWNS; DENTAL ABUTMENTS; nor TOOTH, ARTIFICIAL.Candidiasis, Oral: Infection of the mucous membranes of the mouth by a fungus of the genus CANDIDA. (Dorland, 27th ed)Chromogenic Compounds: Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens).Cross Infection: Any infection which a patient contracts in a health-care institution.Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.Random Amplified Polymorphic DNA Technique: Technique that utilizes low-stringency polymerase chain reaction (PCR) amplification with single primers of arbitrary sequence to generate strain-specific arrays of anonymous DNA fragments. RAPD technique may be used to determine taxonomic identity, assess kinship relationships, analyze mixed genome samples, and create specific probes.TriazolesGenes, Fungal: The functional hereditary units of FUNGI.Cryptococcus neoformans: A species of the fungus CRYPTOCOCCUS. Its teleomorph is Filobasidiella neoformans.Fungal Proteins: Proteins found in any species of fungus.Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.Xenopus: An aquatic genus of the family, Pipidae, occurring in Africa and distinguished by having black horny claws on three inner hind toes.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Zygomycosis: Infection in humans and animals caused by fungi in the class Zygomycetes. It includes MUCORMYCOSIS and entomophthoramycosis. The latter is a tropical infection of subcutaneous tissue or paranasal sinuses caused by fungi in the order Entomophthorales. Phycomycosis, closely related to zygomycosis, describes infection with members of Phycomycetes, an obsolete classification.Mannans: Polysaccharides consisting of mannose units.Centrifugation: Process of using a rotating machine to generate centrifugal force to separate substances of different densities, remove moisture, or simulate gravitational effects. It employs a large motor-driven apparatus with a long arm, at the end of which human and animal subjects, biological specimens, or equipment can be revolved and rotated at various speeds to study gravitational effects. (From Websters, 10th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Antigens, Fungal: Substances of fungal origin that have antigenic activity.DNA, Ribosomal Spacer: The intergenic DNA segments that are between the ribosomal RNA genes (internal transcribed spacers) and between the tandemly repeated units of rDNA (external transcribed spacers and nontranscribed spacers).Evaluation Studies as Topic: Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.Acyl-CoA Oxidase: An enzyme that catalyzes the first and rate-determining steps of peroxisomal beta-oxidation of fatty acids. It acts on COENZYME A derivatives of fatty acids with chain lengths from 8 to 18, using FLAVIN-ADENINE DINUCLEOTIDE as a cofactor.Yeast, Dried: The dry cells of any suitable strain of SACCHAROMYCES CEREVISIAE or CANDIDA. It can be obtained as a by-product from the brewing of beer or by growing on media not suitable for beer production. Dried yeast serves as a source of protein and VITAMIN B COMPLEX.Enoyl-(Acyl-Carrier Protein) Reductase (NADPH, B-Specific): An enzyme that catalyzes the oxidation of acyl-[acyl-carrier protein] to trans-2,3-dehydroacyl-[acyl-carrier protein] in the fatty acid biosynthesis pathway. It has a preference for acyl derivatives with carbon chain length from 4 to 16.Isocitrate Lyase: A key enzyme in the glyoxylate cycle. It catalyzes the conversion of isocitrate to succinate and glyoxylate. EC 4.1.3.1.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Cryptococcosis: Infection with a fungus of the species CRYPTOCOCCUS NEOFORMANS.Agar: A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.Neon: Neon. A noble gas with the atomic symbol Ne, atomic number 10, and atomic weight 20.18. It is found in the earth's crust and atmosphere as an inert, odorless gas and is used in vacuum tubes and incandescent lamps.Trichosporonosis: Fungal infections caused by TRICHOSPORON that may become systemic especially in an IMMUNOCOMPROMISED HOST. Clinical manifestations range from superficial cutaneous infections to systemic lesions in multiple organs.Opportunistic Infections: An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.Industrial Waste: Worthless, damaged, defective, superfluous or effluent material from industrial operations.Mouth: The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.Peptides, Cyclic: Peptides whose amino and carboxy ends are linked together with a peptide bond forming a circular chain. Some of them are ANTI-INFECTIVE AGENTS. Some of them are biosynthesized non-ribosomally (PEPTIDE BIOSYNTHESIS, NON-RIBOSOMAL).Fermentation: Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.Candidiasis, Vulvovaginal: Infection of the VULVA and VAGINA with a fungus of the genus CANDIDA.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Enoyl-CoA Hydratase: An enzyme that catalyzes reversibly the hydration of unsaturated fatty acyl-CoA to yield beta-hydroxyacyl-CoA. It plays a role in the oxidation of fatty acids and in mitochondrial fatty acid synthesis, has broad specificity, and is most active with crotonyl-CoA. EC 4.2.1.17.Itraconazole: A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Aspergillus: A genus of mitosporic fungi containing about 100 species and eleven different teleomorphs in the family Trichocomaceae.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Ketoconazole: Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.Hematologic Neoplasms: Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES.3-Hydroxyacyl CoA Dehydrogenases: Enzymes that reversibly catalyze the oxidation of a 3-hydroxyacyl CoA to 3-ketoacyl CoA in the presence of NAD. They are key enzymes in the oxidation of fatty acids and in mitochondrial fatty acid synthesis.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Hospitals, University: Hospitals maintained by a university for the teaching of medical students, postgraduate training programs, and clinical research.Sugar Alcohols: Polyhydric alcohols having no more than one hydroxy group attached to each carbon atom. They are formed by the reduction of the carbonyl group of a sugar to a hydroxyl group.(From Dorland, 28th ed)Colony Count, Microbial: Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.Antibodies, Fungal: Immunoglobulins produced in a response to FUNGAL ANTIGENS.Pichia: Yeast-like ascomycetous fungi of the family Saccharomycetaceae, order SACCHAROMYCETALES isolated from exuded tree sap.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Aerobiosis: Life or metabolic reactions occurring in an environment containing oxygen.Biofilms: Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.Penicillium: A mitosporic Trichocomaceae fungal genus that develops fruiting organs resembling a broom. When identified, teleomorphs include EUPENICILLIUM and TALAROMYCES. Several species (but especially PENICILLIUM CHRYSOGENUM) are sources of the antibiotic penicillin.
Other Candida species that also fit this profile are C. parapsilosis, C. glabrata, C. tropicalis, C. guillermondii and C. ... Mortality due to C. krusei fungemia is much higher than the more common C. albicans. ... Candida krusei is a budding yeast (a species of fungus) involved in chocolate production. Candida krusei is an emerging fungal ... Pfaller MA, Diekema DJ, Gibbs DL, Newell VA, Nagy E, Dobiasova S, Rinaldi M, Barton R, Veselov A (2008). "Candida krusei, a ...
Candida tropicalis, C. krusei and C. parapsilosis is increasing, perhaps because significant use of fluconazole is common or ... The most commonly known pathogen is Candida albicans, causing roughly 70% of fungemias, followed by Candida glabrata with 10%, ... Fungemia or fungaemia is the presence of fungi or yeasts in the blood. The most common type, also known as candidemia, ... It has been suggested the otherwise immunocompetent patients taking infliximab may be at a higher risk for fungemia. Diagnosis ...
... tropicalis, C. krusei, C. kefyr, C. lusitaniae, and C. dubliniensis. Candida auris is an emerging multidrug-resistant yeast ... Fungemia is one of the most common bloodstream infections in the United States. In general, observed incidence rates have been ... Invasive candidiasis is an infection (candidiasis) that can be caused by various species of Candida yeast. Unlike Candida ... For Candida, the most common is the former, as seen by the emergence of resistant C. glabrata following the introduction of ...
Other medically important species include C. parapsilosis, C. tropicalis and C. dubliniensis. Other Candida species, such as C ... such as fungemia and invasive candidiasis. Oral candidiasis is common in elderly denture wearers. In otherwise healthy ... Candida mesorugosa, Candida neorugosa, Candida pseudorugosa, Candida ranongensis, Candida rugosa and Candida scorzettiae to the ... For example, Candida glabrata, Candida guilliermondii, and Candida lusitaniae are clearly misclassified and will be placed in ...
An unusual feature of the Candida genus is that in many of its species (including C. albicans and C. tropicalis, but not, for ... Systemic fungal infections (fungemias) including those by C. albicans have emerged as important causes of morbidity and ... Candida which can be used to identify different species of candida. Candida albicans can be seen as a tautology. Candida comes ... Candida Genome Database U.S. National Institutes of Health on the Candida albicans genome Mycobank data on Candida albicans ...
... a form of fungemia which may lead to sepsis Invasive candidiasis (disseminated candidiasis) - organ infection by Candida ... Other species pathogenic in humans include C. tropicalis, C. glabrata, C. krusei, C. parapsilosis, C. dubliniensis, and C. ... The name Candida was proposed by Berkhout. It is from the Latin word toga candida, referring to the white toga (robe) worn by ... Candida species and other microorganisms are involved in this complicated fungal infection, but Candida albicans continues to ...
The most commonly known pathogen is Candida albicans, causing roughly 70% of fungemias, followed by Candida glabrata with 10%, Aspergillus with 1% and Saccharomyces as the fourth most common.[citation needed] However, the frequency of infection by C. glabrata, Saccharomyces boulardii, Candida tropicalis, C. krusei and C. parapsilosis is increasing, perhaps because significant use of fluconazole is common or due to increase in antibiotic use.[citation needed]. New emerging pathogen: Candida auris is an emerging multidrug-resistant (MDR) yeast that can cause invasive infections and is associated with high mortality. It was first described in 2009 after being isolated from external ear discharge of a patient in Japan. Since the 2009 report, C. auris infections, specifically fungemia, have been reported from South Korea, India, South Africa, and Kuwait. Although ...
The term "σήψις" (sepsis) was introduced by Hippocrates in the fourth century BC, and it meant the process of decay or decomposition of organic matter.[96][97][98] In the eleventh century, Avicenna used the term "blood rot" for diseases linked to severe purulent process. Though severe systemic toxicity had already been observed, it was only in the 19th century that the specific term - sepsis - was used for this condition. The terms "septicemia", also spelled "septicaemia", and "blood poisoning" referred to the microorganisms or their toxins in the blood and are no longer commonly used.[12][13] The modern term for this is dependent on the microorganism that is present: bacteremia if bacteria are present in the blood at abnormal levels and are the causative issue, viremia for viruses, and fungemia for a fungus.[99]. By the end of the 19th century, it was widely believed that microbes produced substances that could injure the mammalian host and that soluble toxins released ...
A baby bottle is a bottle with a teat (also called a nipple in the US) to drink directly from. It is typically used by infants and young children, or if someone cannot (without difficulty) drink from a cup, for feeding oneself or being fed. It can also be used to feed non-human mammals. In particular it is used to feed infant formula, expressed breast milk or pediatric electrolyte solution. A large-sized bottle typically holds 280 ml; the small size 150 ml.[citation needed] It is composed of a bottle itself, a teat, a ring to seal the teat to the bottle, a cap to cover the teat and optionally a disposable liner. The height-to-width ratio of bottles is high (relative to adult cups) because it is needed to ensure the contents flood the teat when used at normal angles; otherwise the baby will drink air. However, if the bottle is too tall, it easily tips. There are asymmetric bottles that ensure the contents flood the teat if the bottle is held at a certain direction. The teat itself is generally ...
Sensoaryske input wurdt ferwurke troch de harsens foar de werkenning fan gefaar, it finen fan fiedsel, it identifisearjen fan mooglike partners en ferskate oare funksjes. Gesichts-, gefoels- en gehoarynformaasje giet earst nei spesifike kearnen fan de [[talamus]] en dêrnei nei gebieten fan de cortex cerebri dy't by dat spesifike sensoaryske systeem hearre. [[Rook]]ynformaasje (fylogenetysk het oudste systeem) gaat eerst naar de [[bulbus olfactorius]] en dan nei oare dielen fan it olfaktoarysk systeem. [[smaak (sintúch),Smaak]] wurdt fia de harsenstamme laat nei oare dielen fan it betreffende systeem ...
Op it Y-gromosoom sit mar in bytsje erflike ynformaasje. It spilet lykwols wol in krúsjale rol yn de ûntjouwing fan it embryo. It Y-gromosoom set oan ta de produksje fan manlike hormoanen en sadwaande ta de ûntjouwing fan manlike geslachtsskaaimerken. Yn de lichemssellen fan in man sitte altyd in X- en in Y-gromosoom en yn de lichemssellen fan in frou altyd twa X-gromosomen. Erflike ôfwikings dy't keppele binne oan it X-gromosoom komme by manlju altyd ta utering, omdat der foar it defekte gen gjin goede tsjinhinger yn de sel sit. Yn hokker mjitte de ôfwiking by froulju ta utering komt, hinget fan it type ôfwiking ôf: as de ôfwiking in dominant skaaimerk is, dan komt it skaaimerk of de sykte altyd ta utering. Is it skaaimerk dêrfoaroer in resessyf skaaimerk dan komt de ôfwiking allinnich ta utering as de frou draachster is op beide X-gromosomen. In bekend foarbyld is read-grienkleureblinens. Net by alle diersoarten bart de geslachtsbepaling op deselde wize as by de minske, mei in grut ...
The most commonly known pathogen is Candida albicans, causing roughly 70% of fungemias, followed by Candida glabrata with 10%, Aspergillus with 1% and Saccharomyces as the fourth most common.[citation needed] However, the frequency of infection by C. glabrata, Saccharomyces boulardii, Candida tropicalis, C. krusei and C. parapsilosis is increasing, perhaps because significant use of fluconazole is common or due to increase in antibiotic use.[citation needed]. New emerging pathogen: Candida auris is an emerging multidrug-resistant (MDR) yeast that can cause invasive infections and is associated with high mortality. It was first described in 2009 after being isolated from external ear discharge of a patient in Japan. Since the 2009 report, C. auris infections, specifically fungemia, have been reported from South Korea, India, South Africa, and Kuwait. Although ...
V zadnjem desetletju so postale okužbe s kandidami klinično pomembnejše, predvsem zaradi porasta bolnikov z oslabljenim imunskim sistemom, ki so zelo dovzetni za oportunistične okužbe[4] Medtem so razvozlali celoten genom več vrst kandid, kar omogoča nove pristope pri preučevanju, odkrivanju bolezni ter tudi pri razvoju novih protiglivičnih zdravil.[4]. Vrsta Candida antarctica predstavlja vir lipaze, ki se uporablja v industrijske namene. ...
സാലിസിലിക് അമ്ലം പോലെയുള്ള അമ്ലങ്ങളുടെ മിശ്രിതം പല പ്രാവശ്യം പുരട്ടി (Keratoltysis) വിരലുകളിലും മറ്റുമുണ്ടാകുന്ന അരിമ്പാറ മാറ്റാനാകും. ലിക്വിഡ് നൈട്രജൻ പോലുള്ള രാസപദാർഥങ്ങളുപയോഗിച്ചുള്ള ക്രയോസർജറിയിലൂടെ അരിമ്പാറയും അതിനു ചുറ്റുമുള്ള മൃതചർമവും സ്വയം കൊഴിഞ്ഞു പോകും. ലേസർ ചികിത്സ, കാൻഡിഡ (Candida) കുത്തിവയ്പ്, കാന്താരി വണ്ടിന്റെ കാന്താരിഡിൻ എന്ന രാസപദാർഥം ഉപയോഗിച്ചു പൊള്ളിക്കൽ, ...
V zadnjem desetletju so postale okužbe s kandidami klinično pomembnejše, predvsem zaradi porasta bolnikov z oslabljenim imunskim sistemom, ki so zelo dovzetni za oportunistične okužbe[4] Medtem so razvozlali celoten genom več vrst kandid, kar omogoča nove pristope pri preučevanju, odkrivanju bolezni ter tudi pri razvoju novih protiglivičnih zdravil.[4]. Vrsta Candida antarctica predstavlja vir lipaze, ki se uporablja v industrijske namene. ...
Lachance, M.-A.; Bowles, J.M.; Chavarría Díaz, M.M.; Janzen, D.H. (2001) Candida cleridarum, Candida tilneyi and Candida powellii, three new yeast species isolated from insects associated with flowers, In: Int. J. Syst. Evol. Microbiol. 51(3):1201-1207 ...
സാലിസിലിക് അമ്ലം പോലെയുള്ള അമ്ലങ്ങളുടെ മിശ്രിതം പല പ്രാവശ്യം പുരട്ടി (Keratoltysis) വിരലുകളിലും മറ്റുമുണ്ടാകുന്ന അരിമ്പാറ മാറ്റാനാകും. ലിക്വിഡ് നൈട്രജൻ പോലുള്ള രാസപദാർഥങ്ങളുപയോഗിച്ചുള്ള ക്രയോസർജറിയിലൂടെ അരിമ്പാറയും അതിനു ചുറ്റുമുള്ള മൃതചർമവും സ്വയം കൊഴിഞ്ഞു പോകും. ലേസർ ചികിത്സ, കാൻഡിഡ (Candida) കുത്തിവയ്പ്, കാന്താരി വണ്ടിന്റെ കാന്താരിഡിൻ എന്ന രാസപദാർഥം ഉപയോഗിച്ചു പൊള്ളിക്കൽ, ...
Većina lipaza deluje na specifičnoj poziciji na glicerolnoj osnovi lipidnog supstrata (A1, A2 ili A3) (tanka creva). Na primer, lipaza ljudskog pankreasa (HPL),[4] koja je glavni enzim za razlaganje dijetarne masti u ljudskom digestivnom sistemu, konvertuje trigliceridne supstrate ulja u monogliceride i masne kiseline. Nekoliko drugih tipova lipaza se javlja u prirodi, poput fosfolipaza[5] i sfingomijelinaza,[6] međutim one se obično razmatraju zasebno od "konvencionih" lipaza. Neke lipaze izražavaju i izlučuju patogeni organizmi tokom infekcije. Candida albicans ima posebno veliki broj različitih lipaza, sa širokim spektrom lipidnog dejstva. To doprinosi istrajnosti i virulenciji C. albicans u ljudskom tkivu.[7] ...
dans les domaines où le bel est utilisé pour exprimer un rapport de puissance, la puissance étant le plus souvent proportionnelle au carré de la pression, le décibel sera défini comme étant le vingtième du bel, soit dB = B / 20 = 20 log (P/P0 ...
... six Candida duobushaemulonii, four Candida glabrata, and two Candida tropicalis. Agreement of the isolated species occurred in ... Outbreak of fungemia among neonates caused by Candida haemulonii resistant to amphotericin b, itraconazole , and fluconazole. J ... 2005, Sobel 2007). Among C. non-albicans, Candida glabrata and Candida tropicalis had been related with RVVC cases. ... C. albicans (14), Candida duobushaemulonii (6), C. glabrata (4), and C. tropicalis (2) isolates were identified by phenotypic ...
... większość zakażeń Candida spp.) lub egzogennego. W opisywanym przypadku 65-letni pacjent był przyjęty do Kliniki Chirurgii ... Fungemia odcewnikowa o etiologii Candida tropicalis i Candida grabrata - opis przypadku. Catheter-related Candida tropicalis ... Key words: Candida glabrata, Candida tropicalis, fungaemia, treatment of invasive fungal infections ... W posiewie krwi obwodowej i krwi z cewnika centralnego wyhodowano dwa szczepy z rodzaju Candida - Candida tropicalis i Candida ...
On day 12, blood culture yielded Candida tropicalis and C. auris. After that, eight blood cultures performed on hospital days ... Biofilm formation and genotyping of Candida haemulonii, Candida pseudohaemulonii, and a proposed new species (Candida auris) ... First Three Reported Cases of Nosocomial Fungemia Caused by Candida auris Wee Gyo Lee, Jong Hee Shin, Young Uh, Min Gu Kang, ... First Three Reported Cases of Nosocomial Fungemia Caused by Candida auris Wee Gyo Lee, Jong Hee Shin, Young Uh, Min Gu Kang, ...
Candida tropicalis fungemia in a tertiary care hospital. J. Infect., 2003, 46, 150-60. [ Links ]. ... of clinical specimens for Candida albicans, Candida tropicalis, Candida krusei, and Candida (Torulopsis) glabrata. J. Mycol. ... Candida albicans, C. parapsilosis, C. tropicalis, C. glabrata, C. krusei, C. guilliermondii and C. lusitaniae are the main ... Among Candida spp. isolates from 80 patients, 65% were C. albicans, 27.5% C. tropicalis, 2.5% C. glabrata, 2.5% C. krusei and ...
... fungemia explanation free. What is fungemia? Meaning of fungemia medical term. What does fungemia mean? ... Looking for online definition of fungemia in the Medical Dictionary? ... Fungus ball and emphysematous cystitis secondary to Candida tropicalis: a case report ... fungemia. Also found in: Dictionary, Wikipedia. fungemia. [fun-je´me-ah] the presence of fungi in the blood stream. ...
We evaluated isolates from 344 patients with an initial episode of C. tropicalis candidemia. We found that 58 (16.9%) patients ... Our findings suggest cross-boundary expansion of FNS C. tropicalis and highlight the importance of active surveillance of ... Candida tropicalis is the leading cause of non-C. albicans candidemia in tropical Asia and Latin America. ... were infected by fluconazole-nonsusceptible (FNS) C. tropicalis with cross resistance to itraconazole, voriconazole, and ...
Clinical characteristics of Candida tropicalis fungaemia with reduced triazole susceptibility in Taiwan: a multicentre study. ... Resistance rates of non-albicans Candida infections in Taiwan after the revision of 2012 Clinical and Laboratory Standards ...
Candida tropicalis and Penicillium marneffei mixed fungaemia in a patient with Waldenstroms macroglobulinaemia. Eur J Clin ... Woo PC, Lau SK, Lau CC, Chong KT, Hui WT, Wong SS, Penicillium marneffei fungaemia in an allogeneic bone marrow transplant ... A change in antifungal treatment to intravenous amphotericin B led to defervescence and clearance of fungemia. He was given ...
... causing nosocomial fungemia among patients with neutropenia or malignancy (Guinea, 2014). However, limited research has been ... tropicalis strains with diverse virulences. C. tropicalis exhibited strain-dependent filamentation ability, which was ... tropicalis strains with diverse virulences. C. tropicalis exhibited strain-dependent filamentation ability, which was ... Based on the phenotypes of C. tropicalis in our previous study, we selected nine representative strains with different ...
Caspofungin-resistant Candida tropicalis strains causing breakthrough fungemia in patients at high risk for hematologic ... 1,236 of Candida glabrata, 1,238 of Candida parapsilosis, 996 of Candida tropicalis, 270 of Candida krusei, 99 of Candida ... Mutations in the fks1 gene in Candida albicans, C. tropicalis, and C. krusei correlate with elevated caspofungin MICs uncovered ... 8,271 isolates of Candida spp. (4,283 C. albicans, 1,236 C. glabrata, 1,238 C. parapsilosis, 996 C. tropicalis, 270 C. krusei, ...
Community-Acquired Fungemia Due to a Multiple-Azole-Resistant Strain of Candida tropicalis . Jandourek, Alena; Brown, Patricia ... The particular species involved were Candida parapsilosis, Candida tropicalis, Candida glabrata, Candida krusei, Candida ... Candida krusei, Candida parapsilosis species complex and Candida tropicalis causing invasive candidiasis in China: 3 year ... Candida tropicalis, Candida glabrata species complex and Candida krusei... ...
Caspofungin-resistant Candida tropicalis strains causing breakthrough fungemia in patients at high risk for hematologic ... Risk factors for Candida tropicalis fungemia in patients with cancer. Clin. Infect. Dis. 33:1676-1681. ... A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida ... Candida tropicalis and Candida glabrata are important pathogens causing invasive disease, especially in immunocompromised ...
Clinical significance of breakthrough fungemia caused by azole-resistant Candida tropicalis in patients with hematologic ... Clinical significance of breakthrough fungemia caused by azole-resistant Candida tropicalis in patients with hematologic ... Clinical significance of breakthrough fungemia caused by azole-resistant Candida tropicalis in patients with hematologic ... Clinical significance of breakthrough fungemia caused by azole-resistant Candida tropicalis in patients with hematologic ...
Previous Document: Septic arthritis as the first sign of Candida tropicalis fungaemia in an acute lymphoid leukemia pat.... ...
Candida tropicalis: Found in humans and other mammals, fruit, and water. Considered to be allergenic. Considered a true ... Implicated in fungemia, burn infection, and glandular infections in cattle. No toxic diseases have been documented to date. ... Candida albicans: Found in animals and in man. Has been isolated from the skin and mucosa of man, but has also been recovered ... Candida sp.: This genus contains a variety of organisms that have been isolated from the environment, as well as human skin and ...
Caspofungin-resistant Candida tropicalis strains causing breakthrough fungemia in patients at high risk for hematologic ... A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida ... Mutations in the fks1 gene in Candida albicans, C. tropicalis, and C. krusei correlate with elevated caspofungin MICs uncovered ... Rapid emergence of echinocandin resistance during Candida kefyr fungemia treatment with caspofungin. Antimicrob Agents ...
Candida tropicalis (6%). Septic shock occurred in 95 patients. Crude mortality was 35%, the highest in C. tropicalis fungaemia ... Candida albicans was identified in 58% of cases, followed by Candida parapsilosis (15%), Candida glabrata (13%), ...
A non-albicans Candida fungemia in very low birth weight infants in the neonatal intensive care unit of an ?AAA? tertiary ... non-albicans Candida, Candida parapsilosis, Candida tropicalis, fungemia, neonatal intensive care unit, very low birth weight ... non-albicans Candida fungemia in hospital infections has become the focus of attention [11-13]. Nonalbicans Candida fungemia is ... Finkelstein R, Reinhertz G, Hashman N, Merzbach D. Outbreak of Candida tropicalis fungemia in a neonatal intensive care unit. ...
Other Candida species that also fit this profile are C. parapsilosis, C. glabrata, C. tropicalis, C. guillermondii and C. ... Mortality due to C. krusei fungemia is much higher than the more common C. albicans. ... Candida krusei is a budding yeast (a species of fungus) involved in chocolate production. Candida krusei is an emerging fungal ... Candida krusei is a very interesting type of fungus due to the fact that patients that obtain this fungus, result in the lowest ...
Candida tropicalis, C. krusei and C. parapsilosis is increasing, perhaps because significant use of fluconazole is common or ... The most commonly known pathogen is Candida albicans, causing roughly 70% of fungemias, followed by Candida glabrata with 10%, ... Fungemia or fungaemia is the presence of fungi or yeasts in the blood. The most common type, also known as candidemia, ... It has been suggested the otherwise immunocompetent patients taking infliximab may be at a higher risk for fungemia. Diagnosis ...
Candida glabrata, Candida parapsilosis, Candida krusei, Candida tropicalis, Candida dubliniensis, and Candida guilliermondii), ... The increased prevalence of C. parapsilosis within NCAC species was also observed in Portuguese patients with fungaemia,5 ... Las especies de Candida no-Candidaalbicans (CNCA) aisladas fueron Candida parapsilosis, Candida glabrata, Candida tropicalis y ... Non-C. albicans Candida (NCAC) species recovered included Candida parapsilosis, Candida glabrata, Candida tropicalis, and ...
... emerging agent of fungemia in humans. Its actual global distribution remains obscure as the current commercial methods of ... Candida lusitaniae, Candida glabrata and Saccharomyces cerevisiae; thereby indicating its divergence from the active Candida ... More than 99.5 % of the C. auris genomic reads did not align to the current whole (or draft) genome sequences of Candida ... Comparison with the well-studied species Candida albicans showed that it shares significant virulence attributes with other ...
"Candida Tropicalis Vertebral Osteomyelitis: A Late Sequela of Fungemia," Clinical Infectious Diseases, Vol. 19, No. 4, 1994, pp ... Candida albicans, Candida parapsilosis, and Candida glabrata were cultured in 3 of 9 cases respectively. Eight of 9 were ... Shaikh, S. Shaikh, F. Pujol, D. Trauber and M. Sam, "Candida Tropicalis Osteomyelitis: Case Report and Review of Literature," ... D. Sebastiani and F. Galas, "Spondylodiscitis Due to Candida Tropicalis as a Cause of Inflammatory Back Pain," Clinical ...
Candida albicans fungemia.. risk elements for candida tropicalis fungemia in patients with. Candida tropicalis has been ... Candida albicans fungemia.. Candida albicans fungemia candida species niche in. Candida albicans fungemia topical vaginal yeast ... Posted in Albicans, Candida, Candida Albicans Fungemia Treatment, Fungemia, Treatment · Tagged Albicans, Candida, Candida ... Candida Albicans Growth Media. Candida albicans fungemia candida form iyeastcure. Candida albicans fungemia topical vaginal ...
It is critical that the diagnostics and treatment tools to manage antifungal resistance in Candida species be developed now, ... One of the most underappreciated causes of treatment failures in Candida species is biofilm-mediated resistance. Problems ... associated with timely diagnosis and early detection of antifungal resistance in Candida species have not improved over the ... key clinical problems that arise when managing patients with invasive infections caused by antifungal-resistant Candida species ...
  • The fractions were tested at concentrations of 0.5 to 256 µg/mL.Results: The petroleum ether fraction of C. habessinica oleo-gum-resin exhibited the most anti- Candida activity with MIC 50 of 0.5-16 µg/mL. (rjpharmacognosy.ir)