Candida tropicalis: A species of MITOSPORIC FUNGI that is a major cause of SEPTICEMIA and disseminated CANDIDIASIS, especially in patients with LYMPHOMA; LEUKEMIA; and DIABETES MELLITUS. It is also found as part of the normal human mucocutaneous flora.Candida: A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. It is commonly part of the normal flora of the skin, mouth, intestinal tract, and vagina, but can cause a variety of infections, including CANDIDIASIS; ONYCHOMYCOSIS; vulvovaginal candidiasis (CANDIDIASIS, VULVOVAGINAL), and thrush (see CANDIDIASIS, ORAL). (From Dorland, 28th ed)Candida albicans: A unicellular budding fungus which is the principal pathogenic species causing CANDIDIASIS (moniliasis).Candidiasis: Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)Alkanes: The generic name for the group of aliphatic hydrocarbons Cn-H2n+2. They are denoted by the suffix -ane. (Grant & Hackh's Chemical Dictionary, 5th ed)Antifungal Agents: Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.Drug Resistance, Fungal: The ability of fungi to resist or to become tolerant to chemotherapeutic agents, antifungal agents, or antibiotics. This resistance may be acquired through gene mutation.Fungemia: The presence of fungi circulating in the blood. Opportunistic fungal sepsis is seen most often in immunosuppressed patients with severe neutropenia or in postoperative patients with intravenous catheters and usually follows prolonged antibiotic therapy.Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.Candida glabrata: A species of MITOSPORIC FUNGI commonly found on the body surface. It causes opportunistic infections especially in immunocompromised patients.Carnitine O-Acetyltransferase: An enzyme that catalyzes the formation of O-acetylcarnitine from acetyl-CoA plus carnitine. EC 2.3.1.7.Microbodies: Electron-dense cytoplasmic particles bounded by a single membrane, such as PEROXISOMES; GLYOXYSOMES; and glycosomes.Xylitol: A five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.Acetyl-CoA C-Acyltransferase: Enzyme that catalyzes the final step of fatty acid oxidation in which ACETYL COA is released and the CoA ester of a fatty acid two carbons shorter is formed.Mycological Typing Techniques: Procedures for identifying types and strains of fungi.Acetyl-CoA C-Acetyltransferase: An enzyme that catalyzes the formation of acetoacetyl-CoA from two molecules of ACETYL COA. Some enzymes called thiolase or thiolase-I have referred to this activity or to the activity of ACETYL-COA C-ACYLTRANSFERASE.Echinocandins: Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS.Mycology: The study of the structure, growth, function, genetics, and reproduction of fungi, and MYCOSES.DNA, Fungal: Deoxyribonucleic acid that makes up the genetic material of fungi.Candidemia: A form of invasive candidiasis where species of CANDIDA are present in the blood.Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.Microbial Sensitivity Tests: Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).XyloseAzoles: Five membered rings containing a NITROGEN atom.Yeasts: A general term for single-celled rounded fungi that reproduce by budding. Brewers' and bakers' yeasts are SACCHAROMYCES CEREVISIAE; therapeutic dried yeast is YEAST, DRIED.MycosesLipopeptides: Compounds consisting of a short peptide chain conjugated with an acyl chain.Dentures: An appliance used as an artificial or prosthetic replacement for missing teeth and adjacent tissues. It does not include CROWNS; DENTAL ABUTMENTS; nor TOOTH, ARTIFICIAL.Candidiasis, Oral: Infection of the mucous membranes of the mouth by a fungus of the genus CANDIDA. (Dorland, 27th ed)Chromogenic Compounds: Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens).Fungi: A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies.TriazolesGenes, Fungal: The functional hereditary units of FUNGI.Culture Media: Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.Fungal Proteins: Proteins found in any species of fungus.Xenopus: An aquatic genus of the family, Pipidae, occurring in Africa and distinguished by having black horny claws on three inner hind toes.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Trichosporon: A mitosporic fungal genus causing opportunistic infections, endocarditis, fungemia, a hypersensitivity pneumonitis (see TRICHOSPORONOSIS) and white PIEDRA.Mannans: Polysaccharides consisting of mannose units.Antigens, Fungal: Substances of fungal origin that have antigenic activity.Acyl-CoA Oxidase: An enzyme that catalyzes the first and rate-determining steps of peroxisomal beta-oxidation of fatty acids. It acts on COENZYME A derivatives of fatty acids with chain lengths from 8 to 18, using FLAVIN-ADENINE DINUCLEOTIDE as a cofactor.Enoyl-(Acyl-Carrier Protein) Reductase (NADPH, B-Specific): An enzyme that catalyzes the oxidation of acyl-[acyl-carrier protein] to trans-2,3-dehydroacyl-[acyl-carrier protein] in the fatty acid biosynthesis pathway. It has a preference for acyl derivatives with carbon chain length from 4 to 16.Isocitrate Lyase: A key enzyme in the glyoxylate cycle. It catalyzes the conversion of isocitrate to succinate and glyoxylate. EC 4.1.3.1.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Agar: A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.Microbiological Techniques: Techniques used in microbiology.Neon: Neon. A noble gas with the atomic symbol Ne, atomic number 10, and atomic weight 20.18. It is found in the earth's crust and atmosphere as an inert, odorless gas and is used in vacuum tubes and incandescent lamps.Cryptococcus: A mitosporic Tremellales fungal genus whose species usually have a capsule and do not form pseudomycellium. Teleomorphs include Filobasidiella and Fidobasidium.Industrial Waste: Worthless, damaged, defective, superfluous or effluent material from industrial operations.Mouth: The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.Peptides, Cyclic: Peptides whose amino and carboxy ends are linked together with a peptide bond forming a circular chain. Some of them are ANTI-INFECTIVE AGENTS. Some of them are biosynthesized non-ribosomally (PEPTIDE BIOSYNTHESIS, NON-RIBOSOMAL).Fermentation: Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.Candidiasis, Vulvovaginal: Infection of the VULVA and VAGINA with a fungus of the genus CANDIDA.Enoyl-CoA Hydratase: An enzyme that catalyzes reversibly the hydration of unsaturated fatty acyl-CoA to yield beta-hydroxyacyl-CoA. It plays a role in the oxidation of fatty acids and in mitochondrial fatty acid synthesis, has broad specificity, and is most active with crotonyl-CoA. EC 4.2.1.17.Itraconazole: A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Aspergillus: A genus of mitosporic fungi containing about 100 species and eleven different teleomorphs in the family Trichocomaceae.Random Amplified Polymorphic DNA Technique: Technique that utilizes low-stringency polymerase chain reaction (PCR) amplification with single primers of arbitrary sequence to generate strain-specific arrays of anonymous DNA fragments. RAPD technique may be used to determine taxonomic identity, assess kinship relationships, analyze mixed genome samples, and create specific probes.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Ketoconazole: Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.3-Hydroxyacyl CoA Dehydrogenases: Enzymes that reversibly catalyze the oxidation of a 3-hydroxyacyl CoA to 3-ketoacyl CoA in the presence of NAD. They are key enzymes in the oxidation of fatty acids and in mitochondrial fatty acid synthesis.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Colony Count, Microbial: Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.Antibodies, Fungal: Immunoglobulins produced in a response to FUNGAL ANTIGENS.Biofilms: Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.Cryptococcus neoformans: A species of the fungus CRYPTOCOCCUS. Its teleomorph is Filobasidiella neoformans.Evaluation Studies as Topic: Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.Immunocompromised Host: A human or animal whose immunologic mechanism is deficient because of an immunodeficiency disorder or other disease or as the result of the administration of immunosuppressive drugs or radiation.Drug Resistance, Microbial: The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).Blood: The body fluid that circulates in the vascular system (BLOOD VESSELS). Whole blood includes PLASMA and BLOOD CELLS.Acari: A large, subclass of arachnids comprising the MITES and TICKS, including parasites of plants, animals, and humans, as well as several important disease vectors.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Saccharomyces cerevisiae: A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.

In vivo activity of micafungin in a persistently neutropenic murine model of disseminated infection caused by Candida tropicalis. (1/114)

Micafungin is a new echinocandin with broad-spectrum in vitro and in vivo antifungal activity against both Aspergillus and Candida species. We compared the activity of micafungin with that of amphotericin B and fluconazole in a persistently immunocompromised murine model of disseminated candidiasis against a strain of Candida tropicalis that was resistant to amphotericin B and fluconazole in vitro. Mice were rendered persistently neutropenic with multiple doses of cyclophosphamide and infected intravenously with C. tropicalis. Mice were treated with either intraperitoneal amphotericin B (0.5-5 mg/kg per dose), oral fluconazole (50 mg/kg twice a day), intravenous micafungin (1-10 mg/kg per dose) or solvent control for 7 days. Mice were killed at 11 days post-infection and kidneys, lungs, brain and liver removed for quantitative culture. Overall mortality in the model was low, with rates varying between 10% and 25% in treatment groups. Micafungin at doses between 2 and 10 mg/kg were the only regimes able to reduce cfu below the level of detection of tissues infected with C. tropicalis. Micafungin was well tolerated by the mice and was much more effective than amphotericin B or fluconazole against an amphotericin B- and fluconazole-resistant C. tropicalis.  (+info)

Candida tropicalis in a neonatal intensive care unit: epidemiologic and molecular analysis of an outbreak of infection with an uncommon neonatal pathogen. (2/114)

From June to July 1998, two episodes of Candida tropicalis fungemia occurred in the Aristotle University neonatal intensive care unit (ICU). To investigate this uncommon event, a prospective study of fungal colonization and infection was conducted. From December 1998 to December 1999, surveillance cultures of the oral cavities and perinea of the 593 of the 781 neonates admitted to the neonatal ICU who were expected to stay for >7 days were performed. Potential environmental reservoirs and possible risk factors for acquisition of C. tropicalis were searched for. Molecular epidemiologic studies by two methods of restriction fragment length polymorphism analysis and two methods of random amplified polymorphic DNA analysis were performed. Seventy-two neonates were colonized by yeasts (12.1%), of which 30 were colonized by Candida albicans, 17 were colonized by C. tropicalis, and 5 were colonized by Candida parapsilosis. From December 1998 to December 1999, 10 cases of fungemia occurred; 6 were due to C. parapsilosis, 2 were due to C. tropicalis, 1 was due to Candida glabrata, and 1 was due to Trichosporon asahii (12.8/1,000 admissions). Fungemia occurred more frequently in colonized than in noncolonized neonates (P < 0.0001). Genetic analysis of 11 colonization isolates and the two late blood isolates of C. tropicalis demonstrated two genotypes. One blood isolate and nine colonization isolates belonged to a single type. The fungemia/colonization ratio of C. parapsilosis (3/5) was greater than that of C. tropicalis (2/17, P = 0.05), other non-C. albicans Candida spp. (1/11, P = 0.02), or C. albicans (0/27, P = 0.05). Extensive environmental cultures revealed no common source of C. tropicalis or C. parapsilosis. There was neither prophylactic use of azoles nor other risk factors found for acquisition of C. tropicalis except for total parenteral nutrition. A substantial risk of colonization by non-C. albicans Candida spp. in the neonatal ICU may lead to a preponderance of C. tropicalis as a significant cause of neonatal fungemia.  (+info)

Up-regulation of the peroxisomal beta-oxidation system occurs in butyrate-grown Candida tropicalis following disruption of the gene encoding peroxisomal 3-ketoacyl-CoA thiolase. (3/114)

In the yeast Candida tropicalis, two thiolase isozymes, peroxisomal acetoacetyl-CoA thiolase and peroxisomal 3-ketoacyl-CoA thiolase, participate in the peroxisomal fatty acid beta-oxidation system. Their individual contributions have been demonstrated in cells grown on butyrate, with C. tropicalis able to grow in the absence of either one. In the present study, a lack of peroxisomal 3-ketoacyl-CoA thiolase protein resulted in increased expression (up-regulation) of acetoacetyl-CoA thiolase and other peroxisomal proteins, whereas a lack of peroxisomal acetoacetyl-CoA thiolase produced no corresponding effect. Overexpression of the acetoacetyl-CoA thiolase gene did not suppress the up-regulation or the growth retardation on butyrate in cells without peroxisomal 3-ketoacyl-CoA thiolase, even though large amounts of the overexpressed acetoacetyl-CoA thiolase were detected in most of the peroxisomes of butyrate-grown cells. These results provide important evidence of the greater contribution of 3-ketoacyl-CoA thiolase to the peroxisomal beta-oxidation system than acetoacetyl-CoA thiolase in C. tropicalis and a novel insight into the regulation of the peroxisomal beta-oxidation system.  (+info)

Preclinical assessment of the efficacy of mycograb, a human recombinant antibody against fungal HSP90. (4/114)

Mycograb (NeuTec Pharma plc) is a human genetically recombinant antibody against fungal heat shock protein 90 (HSP90). Antibody to HSP90 is closely associated with recovery in patients with invasive candidiasis who are receiving amphotericin B (AMB). Using in vitro assays developed for efficacy assessment of chemotherapeutic antifungal drugs, Mycograb showed activity against a wide range of yeast species (MICs against Candida albicans [fluconazole [FLC]-sensitive and FLC-resistant strains], Candida krusei, Candida tropicalis, Candida glabrata, and Candida parapsilosis, 128 to 256 microg/ml). Mycograb (4 or 8 microg/ml) showed synergy with AMB, the fractional inhibitory index being 0.09 to 0.31. Synergy was not evident with FLC, except for FLC-sensitive C. albicans. Murine kinetics showed that Mycograb at 2 mg/kg produced a maximum concentration of drug in serum of 4.7 microg/ml, a half-life at alpha phase of 3.75 min, a half-life at beta phase of 2.34 h, and an area under the concentration-time curve from 0 to t h of 155 microg. min/ml. Mycograb (2 mg/kg) alone produced significant improvement in murine candidiasis caused by each species: (i). a reduction (Scheffe's test, P < 0.05) in the mean organ colony count for the FLC-resistant strain of C. albicans (kidney, liver, and spleen), C. krusei (liver and spleen), C. glabrata (liver and spleen), C. tropicalis (kidney), and C. parapsilosis (kidney, liver, and spleen) and (ii). a statistically significant increase in the number of negative biopsy specimens (Fisher's exact test, P < 0.05) for C. glabrata (kidney), C. tropicalis (liver and spleen), and C. parapsilosis (liver). AMB (0.6 mg/kg) alone cleared the C. tropicalis infection but failed to clear infections caused by C. albicans, C. krusei, C. glabrata, or C. parapsilosis. Synergy with AMB, defined as an increase (Fisher's exact test, P < 0.05) in the number of negative biopsy specimens compared with those obtained using AMB alone, occurred with the FLC-resistant strain of C. albicans (kidney), C. krusei (spleen), C. glabrata (spleen), and C. parapsilosis (liver and spleen). Only by combining Mycograb with AMB was complete resolution of infection achieved for C. albicans, C. krusei, and C. glabrata.  (+info)

Candida tropicalis expresses two mitochondrial 2-enoyl thioester reductases that are able to form both homodimers and heterodimers. (5/114)

Here we report on the cloning of a Candida tropicalis gene, ETR2, that is closely related to ETR1. Both genes encode enzymatically active 2-enoyl thioester reductases involved in mitochondrial synthesis of fatty acids (fatty acid synthesis type II) and respiratory competence. The 5'- and 3'-flanking (coding) regions of ETR2 and ETR1 are about 90% (97%) identical, indicating that the genes have evolved via gene duplication. The gene products differ in three amino acid residues: Ile67 (Val), Ala92 (Thr), and Lys251 (Arg) in Etr2p (Etr1p). Quantitative PCR analysis and reverse transcriptase-PCR indicated that both genes were expressed about equally in fermenting and ETR1 predominantly respiring yeast cells. Like the situation with ETR1, expression of ETR2 in respiration-deficient Saccharomyces cerevisiae mutant cells devoid of Ybr026p/Etr1p was able to restore growth on glycerol. Triclosan that is used as an antibacterial agent against fatty acid synthesis type II 2-enoyl thioester reductases inhibited growth of FabI overexpressing mutant yeast cells but was not able to inhibit respiratory growth of the ETR2- or ETR1-complemented mutant yeast cells. Resolving of crystal structures obtained via Etr2p and Etr1p co-crystallization indicated that all possible dimer variants occur in the same asymmetric unit, suggesting that similar dimer formation also takes place in vivo.  (+info)

The European Confederation of Medical Mycology (ECMM) survey of candidaemia in Italy: antifungal susceptibility patterns of 261 non-albicans Candida isolates from blood. (6/114)

OBJECTIVES: To analyse the in vitro antifungal susceptibility of 261 non-albicans Candida bloodstream strains isolated during the European Confederation of Medical Mycology survey of candidaemia performed in Lombardia, Italy (September 1997-December 1999). METHODS: In vitro susceptibility to flucytosine, fluconazole, itraconazole, posaconazole and voriconazole was determined using the broth microdilution method described in the NCCLS M27-A guidelines. Etest strips were used to assess susceptibility to amphotericin B. In vitro findings were correlated with the patient's underlying condition and previous antifungal treatment. RESULTS: MICs (mg/L) at which 90% of the strains were inhibited were, respectively, 2 for flucytosine, 8 for fluconazole, 0.5 for itraconazole, 0.25 for voriconazole and 0.25 for posaconazole. Amphotericin B MIC endpoints were <0.50 mg/L in all the isolates tested. Flucytosine resistance was detected in 19 isolates (7%), mainly among Candida tropicalis strains (30%). Innate or secondary fluconazole resistance was detected in 13 strains (5%). Among the 13 patients with fluconazole-resistant Candida bloodstream infection, three were HIV positive, including one treated with fluconazole for oral candidosis; the four who were HIV negative had received the azole during the 2 weeks preceding the candidaemia. Cross-resistance among fluconazole and other azoles was a rare event. CONCLUSIONS: Resistance is still uncommon in non-albicans Candida species recovered from blood cultures. However, in fungaemias caused by C. tropicalis, Candida glabrata and Candida krusei, there is a high prevalence of resistance to fluconazole and flucytosine. Fluconazole resistance should be suspected in patients treated previously with azoles, mainly those with advanced HIV infection.  (+info)

Identification and characterization of the CYP52 family of Candida tropicalis ATCC 20336, important for the conversion of fatty acids and alkanes to alpha,omega-dicarboxylic acids. (7/114)

Candida tropicalis ATCC 20336 excretes alpha,omega-dicarboxylic acids as a by-product when cultured on n-alkanes or fatty acids as the carbon source. Previously, a beta-oxidation-blocked derivative of ATCC 20336 was constructed which showed a dramatic increase in the production of dicarboxylic acids. This paper describes the next steps in strain improvement, which were directed toward the isolation and characterization of genes encoding the omega-hydroxylase enzymes catalyzing the first step in the omega-oxidation pathway. Cytochrome P450 monooxygenase (CYP) and the accompanying NADPH cytochrome P450 reductase (NCP) constitute the hydroxylase complex responsible for the first and rate-limiting step of omega-oxidation of n-alkanes and fatty acids. 10 members of the alkane-inducible P450 gene family (CYP52) of C. tropicalis ATCC20336 as well as the accompanying NCP were cloned and sequenced. The 10 CYP genes represent four unique genes with their putative alleles and two unique genes for which no allelic variant was identified. Of the 10 genes, CYP52A13 and CYP52A14 showed the highest levels of mRNA induction, as determined by quantitative competitive reverse transcription-PCR during fermentation with pure oleic fatty acid (27-fold increase), pure octadecane (32-fold increase), and a mixed fatty acid feed, Emersol 267 (54-fold increase). The allelic pair CYP52A17 and CYP52A18 was also induced under all three conditions but to a lesser extent. Moderate induction of CYP52A12 was observed. These results identify the CYP52 and NCP genes as being involved in alpha,omega-dicarboxylic acid production by C. tropicalis and provide the foundation for biocatalyst improvement.  (+info)

Transformation of fatty acids catalyzed by cytochrome P450 monooxygenase enzymes of Candida tropicalis. (8/114)

Candida tropicalis ATCC 20336 can grow on fatty acids or alkanes as its sole source of carbon and energy, but strains blocked in beta-oxidation convert these substrates to long-chain alpha,omega-dicarboxylic acids (diacids), compounds of potential commercial value (Picataggio et al., Biotechnology 10:894-898, 1992). The initial step in the formation of these diacids, which is thought to be rate limiting, is omega-hydroxylation by a cytochrome P450 (CYP) monooxygenase. C. tropicalis ATCC 20336 contains a family of CYP genes, and when ATCC 20336 or its derivatives are exposed to oleic acid (C(18:1)), two cytochrome P450s, CYP52A13 and CYP52A17, are consistently strongly induced (Craft et al., this issue). To determine the relative activity of each of these enzymes and their contribution to diacid formation, both cytochrome P450s were expressed separately in insect cells in conjunction with the C. tropicalis cytochrome P450 reductase (NCP). Microsomes prepared from these cells were analyzed for their ability to oxidize fatty acids. CYP52A13 preferentially oxidized oleic acid and other unsaturated acids to omega-hydroxy acids. CYP52A17 also oxidized oleic acid efficiently but converted shorter, saturated fatty acids such as myristic acid (C(14:0)) much more effectively. Both enzymes, in particular CYP52A17, also oxidized omega-hydroxy fatty acids, ultimately generating the alpha,omega-diacid. Consideration of these different specificities and selectivities will help determine which enzymes to amplify in strains blocked for beta-oxidation to enhance the production of dicarboxylic acids. The activity spectrum also identified other potential oxidation targets for commercial development.  (+info)

Asian Pacific Journal of Tropical Biomedicine Available online 5 October 2017 In Press, Accepted Manuscript Author links open overlay panelMaria A.Freitas1Antonia T.L.Santos1Antonio J.T.Machado1Ana Raquel P.Silva1Fábia F.Campina1Maria S.Costa1Gioconda M.A.B.Martins1Maria Flaviana B.Morais-Braga1Saulo R.Tintino1Irwin R.A.Menezes1JaimeRibeiro-Filho1Altevir P.Medeiros2Adeliana S.Oliveira3Patrício B.Maracajá4Henrique D.M.Coutinho1 Show more https://doi.org/10.1016/j.apjtb.2017.09.018Get rights and content Open Access funded by Hainan Medical University Under a Creative Commons licenseopen access Abstract Objective To investigate the antifungal activity of the fern species Lygodium venustum and Pityrogramma calomelanos (P. calomelanos) against Candida albicans and Candida tropicalis strains. Methods The microdilution method was used to evaluate the antifungal activity, as well as the modulating effects of ethanolic extracts of these plants in combination with fluconazole. The minimum inhibitory ...
An 18-month epidemiologic investigation of Candida bloodstream infections in a Singapore hospital identified 52 candidemic patients: 36% of whose infections were caused by C. tropicalis, 29% were due to C. albicans, 10% with C. parapsilosis and 21% involved C. glabrata. A predominant clonal C. tropicalis strain was demonstrated. No association with ICU stay, prior exposure to fluconazole/broad-spectrum antibiotics or increased mortality was found in this apparent shift towards non-C. albicans Candida species as the primary agents of candidemia ...
Candida tropicalis ATCC ® 750D-5™ Designation: Genomic DNA from Candida tropicalis CBS 94 (ATCC ® 750™) Application:
Candida tropicalis ATCC ® 750D-5™ Designation: Genomic DNA from Candida tropicalis CBS 94 (ATCC ® 750™) Application:
Candida tropicalis SIS2 protein: regulates expression of sodium-extrusion ATPase encoded by ENA1; isolated from Candida tropicalis; amino acid sequence in first source; GenBank X88900
We report a methodology for the isolation of peroxisome membranes from the yeast Candida tropicalis pK233 grown on oleic acid, and the characterization of the polypeptide and lipid compositions of these membranes. Peroxisomes purified in either sucrose or Nycodenz gradients are treated with Tris-HCl (pH 8.5) and then with sodium carbonate (pH 11.5) to yield a final peroxisome membrane preparation (hereafter called peroxisome membranes). Electron microscopy revealed peroxisome membranes that are approximately 8.1 nm thick, have a typical trilaminar appearance, and form either flattened sheets or whorled structures. Peroxisome membranes contain 3.1% and 2.2% of the total protein of sucrose- and Nycodenz-gradient-purified peroxisomes, respectively. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis showed three predominant polypeptide bands of 34 (PMP 34), 29 (PMP 29), and 24 (PMP 24) × 10(3) Mr in peroxisome membranes. Immunoblotting with an antiserum to PMP 24 showed that PMP ...
Article Biological decolorization of industrial dyes by |italic|Candida tropicalis|/italic| and |italic|Bacillus firmus|/italic|. Disperse dyes are chiefly used by textile industries for the coloration of polyester and cellulose triacetate and their ...
This work aims to utilize fly ash from a thermal power station for melanoidin reduction from distillery effluent by adsorption. To accomplish this, coal fl
ID C5MBN0_CANTT Unreviewed; 570 AA. AC C5MBN0; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 07-JUN-2017, entry version 36. DE SubName: Full=Uncharacterized protein {ECO:0000313,EMBL:EER33047.1}; GN ORFNames=CTRG_03472 {ECO:0000313,EMBL:EER33047.1}; OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Debaryomycetaceae; OC Candida/Lodderomyces clade; Candida. OX NCBI_TaxID=294747 {ECO:0000313,EMBL:EER33047.1, ECO:0000313,Proteomes:UP000002037}; RN [1] {ECO:0000313,EMBL:EER33047.1, ECO:0000313,Proteomes:UP000002037} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313,Proteomes:UP000002037}; RX PubMed=19465905; DOI=10.1038/nature08064; RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S., RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., RA Agrafioti I., Arnaud M.B., Bates S., Brown ...
Kor lovce jsou jedl houby, kter se dlouhodob vyu vaj v lidov medic n v chodn ch zem . Jedn m z nejd le vyu van ch kor lovc je kor lovec je at zvan yamabushitake nebo tak houtou , kter m sv pevn m sto v tradi n nsk medic n v terapii nemoc tr vic ho syst mu. Z padn medic na, kter je k vychvalovan m z zra n m houb m zna n skeptick , dlouhojejich l ebn efekt p ehl ela. Farmaceutick a farmakologick v zkum kor lovc v nich v ak odhalil adu biologicky inn ch l tek, kter mo n jednou najdou uplatn n i v modern medic n . V tomto sm ru jsou zaj mav zejm na polysacharidy s protin dorov m a antimutagenn m inkem. P sob tak jako l tky, kter zvy uj odolnost organismu aktivac imunitn ho syst mu. Aktivuj toti fagocyt rn funkce makrof g , bun k imunitn soustavy, kter se spolu s cytokiny pod lej na nespecifick imunit organismu. Fagocyt rn funkce makrof g m v znam zejm na p i zne kod ov n cizorod ch l tek v organismu, jak mi jsou viry, bakterie nebo pl sn . Makrof gy tak sni uj hladiny p ebyte n ch l tek poch zej c ...
XILITOL MENGGUNAKAN KHAMIR CANDIDA TROPICALIS Bidang Kegiatan : PKM Gagasan Tertulis Diusulkan Oleh : Ketua Kelompok : Affan Iqbal 1. Taufik Rais ( G84080022/2010) ( F24080055/2010) Anggota kelompok : 2. Ayu Fitriana ( H44080050/2010) INSTITUT PERTANIAN BOGOR BOGOR 2010 i . Ringkasan Limbah tandan kosong kelapa sawit (TKKS) di Indonesia yang jumlahnya sangat banyak, menyimpan potensi untuk dimanfaatkan menjadi produk gula yang bernilai tinggi yaitu xilitol. Kandungan hemiselulosa pada limbah ini mencapai 28% berat kering. Hemiselulosa tersebut menghasilkan (±) 33% xilosa sehingga sangat potensial jika diproses menjadi gula xilitol. Proses produksi xilitol pada awalnya menggunakan teknik hidrogenasi xilosa murni yang mahal dan sulit. Tapi dengan ditemukannya proses bioteknologi fermentasi yang memanfaatkan metabolisme khamir. Proses konversi menjadi lebih murah dan efesien. Abstract Waste of Oil palm empty-fruit-bunch (TKKS) in Indonesia is in great number, it has potential to be used to ...
GenEZ™ ORF cDNA clones makes it easy to order customized expression-ready ORF clones from the worlds largest commercial ORF clone database. You can Browse ORF cDNA clones by species Xenopus tropicalis, page 196
Domain architectures containing both Cysteine-rich domain and PH domain-like in Xenopus tropicalis 76_4.2. Links to architectures containing these domain pairs in other groups of genomes are provided. Domain pairs which are not adjacent can be added/removed.
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More... ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Next-day shipping cDNA ORF clones derived from LOC100491574 uncharacterized LOC100491574 available at GenScript, starting from $99.00.
Candida tropicalis is a diploid ascomycetes yeast responsible for 4%-24% of candidemia. Resistance to flucytosine is rarely described for this species but was observed for 45 (35%) of 130 C. tropicalis isolates recovered from blood cultures in the Paris area in a 4-year survey. The aims of this study were to test the hypothesis that the flucytosine-resistant isolates could represent a subgroup and to determine the relationship between epidemiologic and genomic data. Epidemiologic data and gene sequences were analyzed, and molecular typing was performed. Our results suggest that a clone of flucytosine-resistant isolates, associated with malignancies and a lower mortality than that for other C. tropicalis isolates, is widespread in the Paris area. We propose the analysis of 2 polymorphic microsatellite markers coupled with URA3 sequencing to track the clone.
Proven microbial species in burn wounds: Initially Escherichia coli, Pseudomonas putida, Enteroccus faecalis, MSSA, Enterobacter cloacae and Candida tropicalis. Later on positive cultures with Serratia marcescens and Citrobacter freundii (tracheal secretion MSSA and Serratia liquefaciens). Late positive cultures with Trichosporon mucoides or mucormycosis (sensitive to voriconazole and amphotericine B). Proven sepsis with positive blood cultures (MSSA, Candida tropicalis ...
TY - JOUR. T1 - Candida tropicalis Etr1p and Saccharomyces cerevisiae Ybr026p (Mrf1p), 2-enoyl thioester reductases essential for mitochondrial respiratory competence. AU - Torkko, Juha. AU - Koivuranta, Kari. AU - Miinalainen, Ilkka. AU - Yagi, Ahmed. AU - Schmitz, Werner. AU - Kastaniotis, Alexander. AU - Airenne, Tomi. AU - Gurvitz, Aner. AU - Hiltunen, Kalervo. PY - 2001. Y1 - 2001. N2 - We report here on the identification and characterization of novel 2-enoyl thioester reductases of fatty acid metabolism, Etr1p from Candida tropicalis and its homolog Ybr026p (Mrf1′p) from Saccharomyces cerevisiae. Overexpression of these proteins in S. cerevisiae led to the development of significantly enlarged mitochondria, whereas deletion of the S. cerevisiae YBR026c gene resulted in rudimentary mitochondria with decreased contents of cytochromes and a respiration-deficient phenotype. Immunolocalization and in vivo targeting experiments showed these proteins to be predominantly mitochondrial. ...
Phenols and its derivatives are environmental pollutant commonly found in many industrial effluents. It is toxic in nature and causes various health hazards. However, they are poorly removed in conventional biological processes due to their toxicity. Immobilization of microbial cells has received increasing interest in the field of waste treatment and creates opportunities in a wide range of sectors including environmental pollution control. Live cells of phenol-degrading yeast, Candida tropicalis RETL-Cr1, were immobilized on coconut husk and loofah by adsorption. The immobolized particle was packed into biofilter column which used for continuous treatment of a phenol with initial phenol concentration of 3mM. Both loofah and coconut husk have similar phenol biodegradation rate of 0.0188 gL-1h -1 within 15 hours to achieve a phenol removal efficiency of 100 %. However loofah have lower biomass concentration of 4.22 gL-1 compared to biomass concentration on coconut husk, 4.39 gL-1 . Coconut husk ...
This study aimed at investigating the genetic diversity of a panel of Candida africana strains recovered from vaginal samples in different countries. All fungal strains were heterozygous at the mating type-like locus and belonged to the genotype A of Candida albicans. Moreover, all examined C. africana strains lack N-acetylglucosamine assimilation and sequence analysis of the HXK1 gene showed a distinctive polymorphism that impair the utilization of this aminosugar in this yeast.Multilocus sequencing of seven housekeeping genes revealed a substantial genetic homogeneity among the strains, except for the CaMPIb and VPS13 loci which contributed significantly to the classification of our set of C. africana strains into 6 existing diploid sequence types. Amplified fragment length polymorphism (AFLP) fingerprint analysis yielded greater genotypic heterogeneity among the C. africana strains. Overall the data reported here show that in C. africana genetic diversity occurs and the existence of this intriguing
TY - GEN. T1 - Enhanced xylitol production through simultaneous co-consumption of cellobiose and xylose by an engineereed saccharomyces cerevisiae strain. AU - Oh, Eun Joong. AU - Ha, Suk Jin. AU - Kim, Soo Rin. AU - Galazka, Jonathan M.. AU - Cate, Jamie H.D.. AU - Su Jin, Yong. PY - 2011/1/1. Y1 - 2011/1/1. UR - http://www.scopus.com/inward/record.url?scp=85054765849&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=85054765849&partnerID=8YFLogxK. M3 - Conference contribution. AN - SCOPUS:85054765849. SN - 9781618397362. T3 - Fuels and Petrochemicals Division - Core Programming Topic at the 2011 AIChE Annual Meeting. BT - Fuels and Petrochemicals Division - Core Programming Topic at the 2011 AIChE Annual Meeting. PB - AIChE. ER - ...
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Apr 1;65(Pt 4):419-21. doi: 10.1107/S1744309109008719. Epub 2009 Mar 26. Research Support, Non-U.S. Govt
Candida albicans gram poor iyeastcure. Candida albicans gram terrible can girl bladder contamination purpose itching with frame ecology candida and yeast make high-quality you exercise proper hygiene. Is candida albicans gram nice or bad? How can this. Is candida albicans gram fine or poor? Whats the distinction among gram fine and gram poor micro organism? Are they the same as a plague? Candida albicans masquerading as gramnegative. Tion of candida albicans as gramnegative bacilli (gnb) when inoculated into vitek automatic identity systems and can involve grampositive, gramnegative or yeast. Candida albicans parasitic yeast infestation. Candida albicans is a yeast infestation, from a parasite that thrives in warmblooded animals. In the allopathic international of medication its miles referred as a fungus. Candida species superb candida albicans gram superb. Candida species superb candida albicans gram fine or terrible candida species nice candida tropicalis homeopathic. Candida albicans gram ...
Frequencies of sensitisation to Blo t 5 in Taiwanese and Malaysian patients sera were shown to be 91.8% and 73.5%, respectively (24). Other studies have reported Blo t 5 to be a major allergen, with sensitisation rates of up to 70% in populations prone to B. tropicalis allergy (22). Most patients appear to be concurrently sensitised to D. pteronyssinus, and around 18% of patients may be found to be sensitised to B. tropicalis as a result of cross-reactivity of D. pteronyssinus (12). In a Colombian study, 24% of mite-allergic patients were shown to have IgE binding to B. tropicalis extract (20). A study compared the importance of 2 types of sensitisation: to B. tropicalis and D. pteronyssinus among asthma patients from Florida, Puerto Rico, and Brazil; and to D. pteronyssinus among patients from the United States and the United Kingdom. IgE antibodies to recombinant Blo t 5 were found in 45% of sera from B. tropicalis-allergic asthmatics in the group from Florida, Puerto Rico, and Brazil, ...
The caudal-related (Cdx) homeodomain transcription factors have a conserved role in the development of posterior structures in both vertebrates and invertebrates. A particularly interesting finding is that Cdx proteins have an important function in the regulation of expression from a subset of Hox genes. In this study, we report the cloning of cDNAs from the Cdx genes of the amphibian Xenopus tropicalis. Xenopus tropicalis is a diploid species, related to the commonly used laboratory animal Xenopus laevis, and has attracted attention recently as a potential genetic model for animal development. The Xenopus tropicalis cDNAs, Xtcad1, Xtcad2, and Xtcad3, show between 88 and 94% sequence identity with their Xenopus laevis orthologues. This finding corresponds to between 90 and 95% identity at the level of derived amino acid sequence. We also present a detailed description of Xtcad1, Xtcad2, and Xtcad3 expression during normal development. In common with the Cdx genes of other vertebrates, the ...
Candida albicans is part of the human microflora. Excessive and unimpeded growth is generated by a disruption of the sensitive balance and manifests itself in form of oral and/or vaginal soor. Spread of Candida in body tissues causes a systemic candidiasis. Even though there are more than 100 species of Candida, only 7 have been isolated with greater frequency from medical samples. In over 80% of the fungus isolates, Candida albicans and Candida tropicalis are found. Due to colonization of mucous membranes with Candida albicans and its passage into the hosts blood stream, the humoral immune system is stimulated, which results in the production of antibodies against Candida albicans. Generally, shortly after the antigen infringement, Candida albicans-specific IgM-antibodies are produced which are followed by an increase in specific IgG antibodies. Excessive infection of mucous membranes can lead to a high titer of Candida albicans-specific IgA-antibodies.. Test principle: ...
In the present study, we have prepared chitosan-carbon nanotube (Chitosan-CNT) hydrogels by the freeze-lyophilization method and examined their antimicrobial activity. Different concentrations of CNT were used in the preparation of Chitosan-CNT hydrogels. These differently concentrated CNT hydrogels were chemically characterized using Fourier Transform-Infrared Spectroscopy, Scanning Electron Microscopy and Optical microscopy. The porosity of the hydrogels were found to be >94%. Dispersion of chitosan was observed in the CNT matrix by normal photography and optical microscopy. The addition of CNT in the composite scaffold significantly reduced the water uptake ability. In order to evaluate antimicrobial activity, the serial dilution method was used towards Staphylococcus aureus, Escherichia coli and Candida tropicalis. The composite Chitosan-CNT hydrogel showed greater antimicrobial activity with increasing CNT concentration, suggesting that Chitosan-CNT hydrogel scaffold will be a promising
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
|p| Infections caused by non-albicans Candida spp. are an important medical problem in people from risk groups, e.g. hematooncological patients. The aim of this paper was to analyse the in vitro activity of micafungin against 30 clinical isolates of non-albicans Candida spp. (C. glabrata, C. famata, C. tropicalis, C. inconspicua, C. lusitaniae, C. parapsilosis, C. krusei) by way of the E-test procedure, allowing determination of minimal inhibitory concentration (MIC). Data presented in this paper indicate that most of the studied clinical isolates - 27 (90%) showed sensitivity to micafungin, with MIC values ranging from 0.004 to 2 mg/l, while 3 (10%) isolates, including 2 isolates of C. tropicalis and 1 isolate of C. famata, were resistant to micafungin, with MIC values > 32 mg/l. The MIC|sub|50|/sub| and MIC|sub|90|/sub| values of micafungin, defined as MIC inhibited growth of 50% or 90% of the isolates studied, were 0.008 mg/l or 2 mg/l, respectively. In the case of C. glabrata isolates, MICs
TY - JOUR. T1 - Genetic Evaluation of Peroxisomal and Cytosolic Acetoacetyl-CoA Thiolase Isozymes in n-Alkane-Assimilating Diploid Yeast, Candida tropicalis. AU - Ueda, Mitsuyoshi. AU - Kanayama, Naoki. AU - Tanaka, Atsuo. PY - 2000. Y1 - 2000. N2 - The n-alkane-assimilating diploid yeast, Candida tropicalis, possesses two acetoacetyl-CoA thiolase (Thiolase I) isozymes encoded by one allele: peroxisomal and cytosolic Thiolase Is encoded by both CT-T1A and CT-T1B. To clarify the function of peroxisomal and cytosolic Thiolase Is, the site-directed mutation leading Thiolase I ΔC6 without a putative C-terminal peroxisomal targeting signal was introduced on CT-T1A locus in the ct-t1bΔ-null mutant. The C-terminus-truncated Thiolase I was active and solely present in the cytosol. Although the ct-t1aΔ/t1bΔ-null mutants showed mevalonate auxotrophy, the mutants having the C-terminus-truncated Thiolase I did not require mevalonate for growth, as did the strains having cytosolic Thiolase I. These ...
Among the members of the genusCandida, Candida albicans, Candida tropicalis, Candida glabrata, and Candida parapsilosis formerly represented more than 80% of the usual clinical Candida isolates, while Candida kruseiwas only sporadically isolated (11) and was regarded as a commensal organism (13, 24). During the past decade,C. krusei has been recognized as a true pathogen, particularly in immunocompromised patients. The resistance of this organism to fluconazole and the systematic use of this drug may explain the significant increase in the numbers of C. kruseiinfections, (9, 20, 31). In contrast to C. albicans, only a few articles concerning the potential virulence of C. krusei have been published (10, 12, 14, 15, 21,22, 25, 26). Likewise, relatively few studies have been conducted to characterize antigens of C. krusei, and no monoclonal antibody (MAb) specific to this yeast has yet been developed. The present study concerns the description of a MAb (MAb 6B3) specific for the species C. krusei. ...
Candidal infections are extremely common (see the images below).{file44305}{file44306}Candida albicans is the most common cause of human candidal infections, but other pathogenic species include Candida glabrata, Candida parapsilosis, Candida tropicalis, Candida krusei, Candida lusitaniae, and Candida stellatoidea.
Balanitis - an easy to understand guide covering causes, diagnosis, symptoms, treatment and prevention plus additional in depth medical information.No it can not. Log In Sign Up. entertainment tech lifestyle food health politics money sports All Sections.Can valtrex cause yeast infection View pyoderma, emergency care and treatment Sections 1-16.Family physicians also must remember that vaginal yeast infections may be caused by species other than C. albicans, such as Candida glabrata and Candida tropicalis.. ...
Antifungal Activity of Oleoresin and Fractions of Pinus elliottii Engelm and Pinus tropicalis against Phytopathogens. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Loke, John Bernard; Alvarez, Elizabeth; Corredor, J.A.; Folgueras Montiel, Maryluz; Jaramillo, Gustavo; Ceballos, Hernán. 2004. Preliminay evidence of correlation between foliar and root resistance to root rot caused by Phytophthora tropicalis in cassava [poster]. Centro Internacional de Agricultura Tropical (CIAT), Cali, CO. 1 poster ...
We present a genetic map for Xenopus tropicalis, consisting of 2886 Simple Sequence Length Polymorphism (SSLP) markers. Using a bioinformatics-based strategy, we identified unique SSLPs within the X. tropicalis genome. Scaffolds from X. tropicalis genome assembly 2.0 (JGI) were scanned for Simple Sequence Repeats (SSRs); unique SSRs were then tested for amplification and polymorphisms using DNA from inbred Nigerian and Ivory Coast individuals. Thus identified, the SSLPs were genotyped against a mapping cross panel of DNA samples from 190 F2 individuals. Nearly 4000 SSLPs were genotyped, yielding a 2886-marker genetic map consisting of 10 major linkage groups between 73 and 132cM in length, and 4 smaller linkage groups between 7 and 40cM. The total effective size of the map is 1658cM, and the average intermarker distance for each linkage group ranged from 0.27 to 0.75cM. Fluorescence In Situ Hybridization (FISH) was carried out using probes for genes located on mapped scaffolds to assign linkage ...
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Description: The library was made from dT primed cDNA and cloned into vector pCS107. PolyA RNA were primed with an oligo dT primer (5-GACTAGTTCTAGATCGCGAGCGGCCGCCCTTTTTTTTTTTTTTT -3), ligated to a SalI adapter (5-TCGACCCACGCGTCCG-3 and 5-CGGACGCGTGGG-3) and digested with NotI. cDNA was size selected using 1.1% agarose gel electrophoresis (>0.6kb) then ligated into NotI and SalI digested pCS107 vector. Primary library, non-amplified. Library constructed at the DOE Joint Genome Institute (Walnut Creek, CA) as part of the Xenopus Gene Collection project. ...
We have moved to other location and our principal breeding facility will be closed in October. All animals, including breeding pairs of Silurana tropicalis, adult males of Silurana tropicalis, adult Xenopus laevis, albino Xenopus laevis and the whole breeding colony of Xenopus amieti are for ...
Fungi of the genus Candida (C. albicans, C. glabrata, C. krusei, C.tropicalis) are fungi, yeasts found in the normal flora of the skin and mucous membranes of
Learn what candida pelliculosa is and get advice of candida pelliculosa Treatment. Also learn ways to prevent further outbreaks of candida pelliculosa.
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What is Candida? Do you have Candida? Do you know the Symptoms, & Why should you Care? How do you know if Candida is affecting your lifestyle? Its bad yeast in your body, making you feel....
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Candida overgrowth has always been a difficult condition to diagnose, particularly as it was not widely recognized by doctors until recently. The symptoms of Candida are diverse and can appear in many different parts of your body. In this article, I will go through just a few of these symptoms and explain exactly how
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Ako na skrytý problém premnoženej candidy? Premnoženie candidy spôsobuje celý rad problémov. Otestujte sa s Candida Scan a výsledok viete za pár minúť.
Cases of candida are arising within the world. Individuals are suffering from a variety of symptoms and are unaware of the cause. Infections within the body are
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Candida testing does provide more specific insights into underlying mind pathology. From IgG measures to OATS these two tests prove exceedingly helpful.
Candida die off symptoms can last a few days or more. You may feel weak, tired or exhausted and have a flu-like feeing. Heres what you can do...
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Ive had Candida problems for several years now and control it by having a very limited diet. Has anyone here had experience with this life changing condition?
സാലിസിലിക് അമ്ലം പോലെയുള്ള അമ്ലങ്ങളുടെ മിശ്രിതം പല പ്രാവശ്യം പുരട്ടി (Keratoltysis) വിരലുകളിലും മറ്റുമുണ്ടാകുന്ന അരിമ്പാറ മാറ്റാനാകും. ലിക്വിഡ് നൈട്രജൻ പോലുള്ള രാസപദാർഥങ്ങളുപയോഗിച്ചുള്ള ക്രയോസർജറിയിലൂടെ അരിമ്പാറയും അതിനു ചുറ്റുമുള്ള മൃതചർമവും സ്വയം കൊഴിഞ്ഞു പോകും. ലേസർ ചികിത്സ, കാൻഡിഡ (Candida) കുത്തിവയ്പ്, കാന്താരി വണ്ടിന്റെ കാന്താരിഡിൻ എന്ന രാസപദാർഥം ഉപയോഗിച്ചു പൊള്ളിക്കൽ, ...
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We conducted prospective, active population-based surveillance for candidemia (defined as any Candida species isolated from blood) in Atlanta and San Francisco (total population, 5.34 million) during 1992-1993. The average annual incidence of candidemia at both sites was 8 per 100,000 population. The highest incidence (75 per 100,000) occurred among infants ⩽1 year old. In 19% of patients, candidemia developed prior to or on the day of admission. Underlying medical conditions included cancer (26%), abdominal surgery (14%), diabetes mellitus (13%), and human immunodeficiency virus infection (10%). In 47% of cases, species of Candida other than Candida albicans were isolated, most commonly Candida parapsilosis, Candida glabrata, and Candida tropicalis. Antifungal susceptibility testing of 394 isolates revealed minimal levels of azole resistance among C. albicans, C. tropicalis, and C. parapsilosis. These data document the substantial burden of candidemia and its changing epidemiology. Continued ...
Fluconazole (Diflucan; Pfizer, Inc., New York, NY) is a synthetic triazole antifungal bourgeois with capacity against a wide assortment of pathogenic barm, including Candida albicans and Candida tropicalis. Potentially resistant strains include Candida glabrata, Candida lusitaniae, and Candida krusei. Fluconazole has gained wide clinical assent because of its favorable pharmacokinetics and excellent condom life. In healthy subjects and patients not in an intensive care unit (ICU), fluconazole is almost completely absorbed, with an absolute bioavailability of 90% after oral justice, and exhibits a half-life of approximately 30 work time, which allows for once-daily dosing. Fluconazole is eliminated predominantly by the kidneys; renal permit accounts for 80% of totality permit ...
Read "In vitro effects of promethazine on cell morphology and structure and mitochondrial activity of azole-resistant Candida tropicalis, Medical Mycology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
This study by investigators at Bausch + Lomb investigated biocidal activity to better simulate polymicrobial contamination of contact lens cases. The organisms used were not the standard five organisms, but rather six separate mixtures of organisms that included P. aeruginosa and one of the following: Candida albicans, Candida tropicalis, Fusarium solani, Fusarium oxysporum, Aspsergillus brasiliensis and Aspergillus fumigatus. Ten percent organic soil was added for an additional challenge. The mixed inoculum was then used to challenge the MPS. Four- and six-hour time points were evaluated. Results were recorded using log reductions.. Results varied according to the MPS used. Fungi were recovered more than P. aeruginosa. Recovery for the four-hour time point ranged from 0.2 log reduction to ,4.6 (no microbial recovery observed). The six-hour time point ranged from 0.0 log reduction to ,4.6 log reductions.. This study demonstrated that MPS have a broad range of in vitro antimicrobial activity ...
Candida spp. infections are a major cause of morbidity and mortality in critically ill patients. Candida auris is an emerging multi-drug-resistant fungus that is rapidly spreading worldwide. Since the first reports in 2009, many isolates across five continents have been identified as agents of hospital-associated infections. Independent and simultaneous outbreaks of C. auris are becoming a major concern for healthcare and scientific community. Moreover, laboratory misidentification and multi-drug-resistant profiles, rarely observed for other non-albicans Candida species, result in difficult eradication and frequent therapeutic failures of C. auris infections. The aim of this review was to provide an updated and comprehensive report of the global spread of C. auris, focusing on clinical and microbiological characteristics, mechanisms of virulence and antifungal resistance, and efficacy of available control, preventive, and therapeutic strategies.
Although thoroughly studied in terms of structural, biochemical and biophysical characteristics, the biological functions of avidins are not fully understood. Here, we expand the research on avidins by reporting xenavidin, the first avidin-like protein from a frog, which was identified as an expressed sequence tag (EST) from the Xenopus tropicalis genome project. Avidins appear to be conserved among egg-laying vertebrates [3, 4, 6] and are thought to have a role as defence proteins against microbial infections [43, 44]. Bird eggs contain egg yolk, the compartment for embryonic development, and the egg white that surrounds the egg yolk provides both nutrients and protection for the embryo. In frogs, the equivalent to egg white is called egg jelly [45]. The avidin content of egg jelly may have an important role in the embryonic development of frogs, a hypothesis that is also supported by recent studies within natural bird populations, in which the concentration of avidin in egg white appears to be ...
N-Fuzed Candida is a revolutionary product that infuses the essence of Candida albicans into the crystalline structure of water. Using the same principle as homeopathics, "like treats like", N-Fuzed Candida Quick Cleanse supports the bodys immune system in removing Candida from the blood and soft tissues while it helps to restore natural balance in the intestinal tract.* In fact, independent laboratory studies confirm that N-Fuzed Candida inhibits Candida in vitro in just 3 days. What is Candida albicans?. Candida albicans is a naturally occurring genus of yeast that lives in your intestinal tract with many other microorganisms known as probiotics. Problems happen, however, when something upsets the balance of these organisms. Candida begins to multiply and overpopulate. What typically triggers this is the use of pharmaceutical antibiotics or birth control pills. A diet dominated by processed foods, sugar, and alcohol will exasperate this condition significantly ...
Candida is a yeast microorganism that commonly lives in our intestinal tract. It shares space with a variety of other microorganisms, mostly helpful bacteria such as those found in probiotics, and is usually harmless. An overgrowth of Candida however, is a common problem and can cause several unpleasant symptoms. Gas, bloating, fatigue, joint pain and stiffness can make many day-to-day situations stressful and a cause for anxiety.. As Candida is the result of lifestyle choices that create a systemic imbalance, the solution is to stop feeding the yeast and restore equilibrium. If the natural pH of the body is corrected, disease is less likely to develop. If the presence of Candida is confirmed, a treatment protocol of probiotics and herbal remedies that are toxic to Candida are highly recommended. This self-test can help determine if you have Candida, but only as a general guide. Before relying on the results, more accurate medical testing is advisable to eliminate the possibility of other ...
Candida Albicans is a naturally occurring form of yeast that resides inside our bodies that can, under the right circumstances cause many unpleasant symptoms including weight gain, joint pain and digestion problems. Candida is just one of several micro-organisms that live in our gut, mouth and instestine. Sometimes Candida can reproduce at an overwhelming rate and produce what is […]. ...
This pack is for those suffering from Candida overgrowth with more severe GI distress, as it contains more gut healing supplementation than the standard Candida Protocol Pack. Candida (harmful yeast overgrowth) wrecks havoc on our health. The candida needs to be eradicated, good bacteria needs to be repopulated and th
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Candida albicans is a naturally occurring yeast that typically resides in the gut as part of the normal gut flora. Candida Support is a combination of tradition
The source of this test is unknown, but it has been around a long time and is quite reliable in the diagnosis of Candida albicans overgrowth. It is known as the Candida saliva test or the Candida spit test.
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... je pleseň, ktorá prebýva v našich črevách a patrí spolu s tými "dobrými baktériami" medzi stavebný kameň našej črevnej mikroflóry. Teda je pre nás prospešná, no občas sa stane, že sa candida premnoží, a aj tu platí, že všetkého veľa škodí. Jej premnoženie súvisí s oslabeným imunitným systémom. Dnešná doba je, žiaľ, taká, že sa prepchávame antibiotikami nielen u lekára, ale pridávame ich aj do stravy pre zvieratá, aby sme mali viac zdravého mäsa, no potom to mäso plné antibiotík konzumujeme. Antibiotiká narúšajú náš črevný systém a zabíjajú aj tieto pre nás prospešné baktérie. Keď je imunita narušená candida sa rozmnoží a môže spôsobiť rôzne zdravotné ťažkosti. Symptómy sa prejavujú vo forme migrén, nevoľnosti, silnej únavy, bolesti kĺbov a pod. Pri objavení ktorýchkoľvek z príznakov treba vyhľadať lekára a treba dodržiavať niekoľko zásadných rád v stravovaní. (viac…). ...
What is candida and how do you treat it, naturally? In this article I discuss the disorder that affects 50-80 percent of the US population.
The Candida will either move through the digestive tract to be eliminated through the colon, or be filtered out of the blood by the kidneys. Thus the liver will not be working harder to process dead Candida or other pathogens and their toxins. It will be able to concentrate on removing toxins from cells as they start to detoxify ...
Im not a doctor, Im not a robot... Im also not trying to sell you anything. What I am is someone who has suffered from candida her whole life and recently found the only remedy (out of the 300 that ...
The Detox stage of the Anti Candida Diet Plan could never be described as enjoyable but maybe a necessary evil is a more accurate description. It is crucial to the success of your Candida cleanse and needs to be taken seriously for best results. The detox gives your body a vital rest period to release toxins and flush out […]. ...
Before we dig deeper with Naturally Eliminating Candida Review, let us first understand what Candida means since there are still some who dont have any clue...
... If you have a candida overgrowth symptom, learn how to treat it with the help of an integrative practitioner.
... If you have a candida overgrowth symptom, learn how to treat it with the help of an integrative practitioner.
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Our comprehensive article on Candida helps you identify symptoms, understand treatment options, and learn how to heal. Click now and start healing!
Candida Treatment involves either the traditional method of using anti-fungals and the natural method using diet and lifestyle changes. We explore both options.
My lifetime of perfect health was marred by an awful rash that turned out to be candida symptoms - heres what I did to cure it naturally after seeing an M.D. and a Naturopath.
Candida is not a serious condition. But if this infection is not treated on time then it would spread and cause discomfort as well.
In 1986, Candida Royale retired from performing in hard core films, and decided to make some of her own, but with a huge difference from the norm. She wanted to create hard core films that portrayed healthy consensual sex in[…]↓ Read the rest of this entry…. ...
Nick has been using Spooky2 products for over a year and is rapidly approaching two years now. The reason he used so long is Spooky2 deals with his body.
While somebody is not experiencing nicely on the continuous foundation, it may make sure they are become and take out in the organization of the regular family members who might provide a help program to them. The infection continues to be recognized even to have terrible results on somebody, even though it is generally not really a key disease or to get severe ...
In the present study, we manufactured rice miso supplementary with black soybean, buckwheat and adzuki bean. We analyzed DPPH radical scavenging activity, melanoidin, peptide, reducing sugar content, and lipase inhibitory activity in various rice miso products at different fermentation periods (3, 6, 24, 36 months), respectively. DPPH radical scavenging activity, melanoidin content and lipase inhibitory activity in various rice miso products increased with prolonging the fermentation period. We found positive relationships between melanoidin content and DPPH radical scavenging activity, and lipase inhibitory activity. The correlation coefficients were more than 0.75, respectively. Rice miso supplementary with black soybean (RM-BS), rice miso supplementary with buckwheat (RM-BW) and rice miso supplementary with adzuki bean (RM-AB) exhibited significant higher DPPH radical scavenging activity, melanoidin and lipase inhibitory activity than RM (rice miso; control), respectively. We considered that due to
Candidiasis has become an important concern for clinical practice, especially with the increasing incidence of immunocompromised patients. In this scenario, the development resistance to fluconazole presents a challenge for treating these opportunistic infections. The aim of this study was to evaluate some epidemiology features of Candidainfections in a Brazilian University Hospital using data, previously unavailable. We observed that 44% of the 93 clinical isolates tested, belonged to Candida albicansspecies and 56% belonged to non-Candida albicansspecies (mainly Candida tropicalis and Candida glabrata). Most strains were isolated from urine samples where C. albicans was predominantly detected. 29 strains presented a fluconazole resistance phenotype and of these, 22 were chemosensitised by FK506, a classical inhibitor of ABC transporters related to azoles resistance. These data suggest the probable role of efflux pumps in this resistance phenotype. Our study highlights the need for developing ...
Kill candida with lemon candida albicans kako je leciti. Kill candida with lemon recall youre imagined to eat them heated and in small amounts, yeast infection symptoms blood in urine candida albicans therapie nystatin;. Candida i rak kako leciti? Facebook. Oct 26, 2011 Šta je candida? Candida albicans je gljivica, vesnamihajlovicblog.Wordpress/2011/10/27/candidairakkakoleciti/.. Candida i rak kako leciti? Weblog vesne mihajlović. Šta je candida? Candida albicans je gljivica, koja je u određenim količinama prisutna u svakome od nas. Candida i rak kako leciti?. Candida no intestinal como tratar candida albicans kako. Commonly via a mixture of sexual counseling and with the aid of use of unique dilators. Candida no intestinal como tratar my present day plan candida albicans remedio homem.. Candida i rak kako leciti? Facebook. · Šta je candida? Candida albicans je gljivica, vesnamihajlovicblog.Wordpress/2011/10/27/candidairakkakoleciti/.. Candida i kako je leciti probiotic mouth rinse for ...
Looking for online definition of candidaemia in the Medical Dictionary? candidaemia explanation free. What is candidaemia? Meaning of candidaemia medical term. What does candidaemia mean?
... and the human pathogens Candida albicans and Candida tropicalis. Parasexuality has become a useful tool for industrial ... "Parasexuality and Ploidy Change in Candida tropicalis." Eukaryotic Cell. 2013 Dec; 12(12): 1629-1640. Alexopoulos CJ, Mims CW, ... "Completion of a parasexual cycle in Candida albicans by induced chromosome loss in tetraploid strains." EMBO J. 2003 May 15;22( ...
Candida tropicalis, Candida maltose, Rhizobium leguminosarum, and Nocardia sp.. These bacteria subsequently employ 1,2-CTD in ... Krug, M; Straube, G (1986). "Degradation of phenolic compounds by the yeast Candida tropicalis HP 15. II. Some properties of ... assimilating yeast Candida maltose". Agric. Biol. Chem. 52 (2): 585-587. doi:10.1271/bbb1961.52.585. Chen, Y; Love II, C (1990 ...
This enzyme has been found in the following species: Yeast Candida cloacae Candida tropicalis Starmerella bombicola Yarrowia ... Dickinson, FM; Wadforth, C (1992). "Purification and some properties of alcohol oxidase from alkane-grown Candida tropicalis". ... The enzyme is an octamer of ~46kD subunits (except in C. tropicalis, in which it is a dimer of subunits ~70kD). It is a ... This enzyme can be induced in many Candida yeast strains by growing them on long-chain alkanes as the major food source. Long- ...
... and characterization of a D-arabinitol-specific dehydrogenase from Candida tropicalis". Biochem. Biophys. Res. Commun. 196 (3 ... "D-arabitol metabolism in Candida albicans: studies of the biosynthetic pathway and the gene that encodes NAD-dependent D- ...
... encoding an NADH-preferring xylose reductase from Candida parapsilosis, and its functional expression in Candida tropicalis". ... crystallization and preliminary X-ray crystallographic analysis of xylose reductase from Candida tropicalis". Acta Crystallogr ... Nidetzky, B.; Bruggler, K.; Kratzer, R.; Mayr, P. (2003). "Multiple forms of xylose reductase in Candida intermedia: comparison ... H-dependent aldose reductase from the xylose-assimilating yeast Candida tenuis. Isolation, characterization and biochemical ...
MA Al-Fattani & LJ Douglas (Aug 2006). "Biofilm matrix of Candida albicans and Candida tropicalis: chemical composition and ... It is marketed as an enzymatic remedy to treat the yeast infection candida. Having the status of a dietary supplement, its ... Masuoka, J (April 2004). "Surface Glycans of Candida albicans and Other Pathogenic Fungi". Clinical Reviews of Microbiology. 17 ... but there is no mention of cellulose nor is cellulose mentioned as a cell wall component in candida albicans, the yeast strain ...
"Peroxisomal isocitrate lyase of the n-alkane-assimilating yeast Candida tropicalis: gene analysis and characterization". J. ...
"Peroxisomal isocitrate lyase of the n-alkane-assimilating yeast Candida tropicalis: gene analysis and characterization". J. ... This is the case for fungi such as Candida albicans, which inhabits the skin, mouth, GI tract, gut and vagina of mammals and ...
"Genetic evaluation of physiological functions of thiolase isoenzymes in the n-alkalane-assimilating yeast Candida tropicalis". ...
Common yeast cells used in effectly fermenting and producing xylitol are Candida tropicalis and Candida guilliermondii. One ... "Screening of yeasts for production of xylitol from D-xylose and some factors which affect xylitol yield in Candida ...
It is now produced by fermentation of long-chain alkanes with a specific strain of Candida tropicalis. Traumatic acid is its ... Brassylic acid can be produced from erucic acid by ozonolysis but also by microorganisms (Candida sp.) from tridecane. This ...
A second analysis of cauim made from rice and manioc also showed the presence of yeasts, chiefly Candida tropicalis. Drink ...
It is active against fungi and yeasts such as Candida albicans, Candida tropicalis, Saccharomyces cerevisiae, Penicillium ...
Effluents can be first processed by a strain of yeast Candida tropicalis JKS2 then post-treated by photocatalytic processes to ... Candida tropicalis Jks2 -Tio2/Uv. Iranian Journal of Environmental Health Science & Engineering 2012, 9 (33), 1-7. Couto, S.R. ...
"Crystallization and preliminary crystallographic data of 2-enoyl-CoA hydratase 2 domain of Candida tropicalis peroxisomal ...
A biotechnology is used to convert paraffin wax into DDDA with a special strain of Candida tropicalis yeast in a multi-step ...
Candida glabrata, Candida tropicalis, Candida parapsilosis, Candida krusei and Cryptococcus neoformans. A methanolic extract ... Leaf extracts strongly affect the fungi causing oral candidiasis and skin infections - Candida albicans, ...
Extracts of the puffball have also been reported to have antifungal activity against Candida albicans, C. tropicalis, ...
Candida species such as C. albicans, C. glabrata, C. krusei, C. tropicalis, C. parapsilosis, and C. guillermondiiare the most ... Linear gingival erythema is classified as a candida-associated lesion, that is to say Candida species are involved, and in some ...
Other Candida species that also fit this profile are C. parapsilosis, C. glabrata, C. tropicalis, C. guillermondii and C. ... Candida krusei is a budding yeast (a species of fungus) involved in chocolate production. Candida krusei is an emerging fungal ... Candida krusei is a very interesting type of fungus due to the fact that patients that obtain this fungus, result in the lowest ... Candida krusei can be successfully treated with voriconazole, amphotericin B, and the echinocandins micafungin, caspofungin, ...
Candida tropicalis, Candida glabrata, Candida parapsilosis, Candida krusei, or other species (Candida stellatoidea, Candida ... pseudotropicalis, Candida famata, Candida rugosa, Candida geotrichium, Candida dubliniensis, and Candida guilliermondii). C. ... More Candida is detected in the early morning and the late afternoon. The greatest quantity of Candida species are harbored on ... Oral carriage of Candida is pre-requisite for the development of oral candidiasis. For Candida species to colonize and survive ...
... vaginitis caused by proliferation of Candida albicans, Candida tropicalis, Candida krusei Bacterial vaginosis: vaginitis caused ... The yeast Candida albicans is the most common cause of vaginitis. Specific forms of vaginal inflammation include the following ... such as gonorrhea and candida infection) Vaginitis is the disruption of the healthy vaginal microbiota. The vaginal microbiota ...
Candida tropicalis, C. krusei and C. parapsilosis is increasing, perhaps because significant use of fluconazole is common or ... The most commonly known pathogen is Candida albicans, causing roughly 70% of fungemias, followed by Candida glabrata with 10%, ... The most common type, also known as candidemia, candedemia, or systemic candidiasis, is caused by Candida species, but ... https://www.cdc.gov/fungal/diseases/candidiasis/candida-auris-alert.html Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, ...
... as well as yeasts such as Candida albicans, Candida tropicalis, and Candida krusei. There is also evidence of antibacterial ...
Bacillus cereus and the fungus Candida tropicalis, but did not show any biological activity. Two alkaloids, infractopicrin and ...
Renewable energy portal Energy portal Algae fuel Biodiesel Biofuel Biorefinery Butanol Butanol fuel Candida tropicalis Carbon ...
Candida liik Candida krusei. liik Candida lambica. liik Candida tropicalis. liik Candida utilis. suguk. Saccharomycodaceae. ... Candida albicans, Cryptococcus neoformans, C. tropicalis, C. stellatoidea, C. glabrata, C. krusei, C. parapsilosis, C. ... guilliermondii, C. viswanathii, C. lusitaniae, Rhodotorula mucilaginosa, Candida glabrata, Torulopsis glabrata, C. ... Stoyan T, Carbon J. (2004). "Inner Kinetochore of the pathogenic yeast Candida glabrata". Eukaryotic Cell 3 (5): 1154-1163. doi ...
... tropicalis. Antifungal activity is observed for sequential incubation of Candida with lactoferrin and then with fluconazole, ... Candida albicans could also be completely eradicated with a mixture containing lactoferrin, lysozyme and itraconazole in HIV- ... Lactoferrin also acts against the Candida albicans - a diploid fungus (a form of yeast) that causes opportunistic oral and ... Fluconazole has long been used against Candida albicans, which resulted in emergence of strains resistant to this drug. However ...
Candida tropicalis",. abstract = "The n-alkane-assimilating diploid yeast, Candida tropicalis, possesses two acetoacetyl-CoA ... N2 - The n-alkane-assimilating diploid yeast, Candida tropicalis, possesses two acetoacetyl-CoA thiolase (Thiolase I) isozymes ... AB - The n-alkane-assimilating diploid yeast, Candida tropicalis, possesses two acetoacetyl-CoA thiolase (Thiolase I) isozymes ... The n-alkane-assimilating diploid yeast, Candida tropicalis, possesses two acetoacetyl-CoA thiolase (Thiolase I) isozymes ...
Candida tropicalis Etr1p and Saccharomyces cerevisiae Ybr026p (Mrf1p), 2-enoyl thioester reductases essential for ... Candida tropicalis Etr1p and Saccharomyces cerevisiae Ybr026p (Mrf1p), 2-enoyl thioester reductases essential for ... Candida tropicalis Etr1p and Saccharomyces cerevisiae Ybr026p (Mrf1p), 2-enoyl thioester reductases essential for ... Candida tropicalis Etr1p and Saccharomyces cerevisiae Ybr026p (Mrf1p), 2-enoyl thioester reductases essential for ...
Candida tropicalis, Candida glabrata, Candida parapsilosis, Candida krusei, or other species (Candida stellatoidea, Candida ... pseudotropicalis, Candida famata, Candida rugosa, Candida geotrichium, Candida dubliniensis, and Candida guilliermondii). C. ... More Candida is detected in the early morning and the late afternoon. The greatest quantity of Candida species are harbored on ... Oral carriage of Candida is pre-requisite for the development of oral candidiasis. For Candida species to colonize and survive ...
Candida Albicans Glabrata Tropicalis. rapid take a look at candida albicans, rapid check candida albicans. Speedy take a look ... Candida rapid test otc fungal infection medicines with candida and crimson eyes and candida tropicalis diflucan discover facts ... Candida Albicans Lung Cancer, How To Treat Candida Albicans Fungus, Candida Albicans On Lips, Candida Albicans Treatment In ... Candida Albicans Skin Diseases, Candida Albicans Pode Causar Cancer, Candida Albicans Intestinal Infection, Candida Albicans ...
... six Candida duobushaemulonii, four Candida glabrata, and two Candida tropicalis. Agreement of the isolated species occurred in ... 2005, Sobel 2007). Among C. non-albicans, Candida glabrata and Candida tropicalis had been related with RVVC cases. ... C. albicans (14), Candida duobushaemulonii (6), C. glabrata (4), and C. tropicalis (2) isolates were identified by phenotypic ... Reclassification of the Candida haemulonii complex as Candida haemulonii (C. haemulonii group I), C. duobushaemulonii sp. nov ...
Recurrence of VVC due to Candida albicans in women with documented RVVC over the 6-month post-vaccination period in the NDV-3A ... tropicalis, etc.) as the cause of vaginitis. ... Recurrence of VVC due to Candida albicans in women with ... one of the previous episodes confirmed by positive results from a diagnostic lab test specific for the presence of Candida. ...
Candida tropicalis ATCC ® 750™ Designation: [1909, ATCC 4563, ATCC 7349, CBS 94, CCRC 20520, IFO 1070, IFO 1400, JCM 1541, NRRL ... Candida tropicalis multidrug resistance protein (MDR1) gene, Nucleotide (GenBank) : AF218992 Candida tropicalis strain ATCC ... Candida tropicalis alkane-inducible cytochrome P450 gene, complete Nucleotide (GenBank) : U00675 Candida tropicalis D- ... Nucleotide (GenBank) : M60308 C. tropicalis small subunit ribosomal RNA. Nucleotide (GenBank) : M23673 Candida tropicalis (ATCC ...
Candida tropicalis ATCC ® 13803™ Designation: FDA PCI M-59 Application: Assay of amphotericin B fungizone Assay of nystatin ... Candida tropicalis (Castellani) Berkhout (ATCC® 13803™) Strain Designations: FDA PCI M-59 / Product Format: freeze-dried ... Nucleotide (GenBank) : AF201686 Candida tropicalis agglutinin-like protein 1 (ALST1) gene, partial ... Nucleotide (GenBank) : AF211865 Candida tropicalis strain ATCC 13803 agglutinin-like protein Alst2p ...
Proteasome - Candida tropicalis [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show description , User data ...
In the genus Candida, there are other species that are synonym of Candida tropicalis. Candida albicans is taxonomically close ... Candida tropicalis is a species of yeast in the genus Candida. It is a common pathogen in neutropenic hosts, in whom it may ... Candida parapsilosis and Candida tropicalis: biology, epidemiology, pathogenicity and antifungal resistance". FEMS Microbiology ... C. tropicalis is the second most virulent Candida species that can significantly affect by spreading through the weakened ...
"Isolation and nucleotide sequence of the extracellular acid protease gene (ACP) from the yeast Candida tropicalis.". Togni G., ... sp,Q00663,CARP_CANTR Candidapepsin OS=Candida tropicalis OX=5482 GN=SAPT1 PE=1 SV=1 ... Candida tropicalis (Yeast). ,p>This subsection of the ,a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names ...
Proteogenomics of Candida tropicalis--An Opportunistic Pathogen with Importance for Global Health.. Datta KK1,2, Patil AH1,2, ... Candida tropicalis is an opportunistic pathogen that causes candidiasis, for example, in immune-compromised individuals, cancer ... Proteogenomics of Candida tropicalis-An Opportunistic Pathogen with Importance for Global Health ... Proteogenomics of Candida tropicalis-An Opportunistic Pathogen with Importance for Global Health ...
XR of molecular mass 36.6 kDa from Candida tropicalis was crystallized using the hanging-drop vapour-diffusion method. ... Purification, crystallization and preliminary X-ray crystallographic analysis of xylose reductase from Candida tropicalis.. ... Purification, crystallization and preliminary X-ray crystallographic analysis of xylose reductase from Candida tropicalis ... Purification, crystallization and preliminary X-ray crystallographic analysis of xylose reductase from Candida tropicalis ...
... isolated from Candida tropicalis; amino acid sequence in first source; GenBank X88900 ... Candida tropicalis SIS2 protein: regulates expression of sodium-extrusion ATPase encoded by ENA1; ... Candida tropicalis SIS2 protein. Subscribe to New Research on Candida tropicalis SIS2 protein ... regulates expression of sodium-extrusion ATPase encoded by ENA1; isolated from Candida tropicalis; amino acid sequence in first ...
sp,C5M4D4,CHO2_CANTT Phosphatidylethanolamine N-methyltransferase OS=Candida tropicalis (strain ATCC MYA-3404 / T1) OX=294747 ... Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast). ,p>This subsection of the ,a href="http://www.uniprot.org/help/names_ ... Candida/Lodderomyces clade › CandidaCandida tropicalis ... Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast). Status ...
Search results for Candida tropicalis. A partial match was found for candida tropicalis Please try browsing our store to find ...
... the prevalence of Candida tropicalis as a causative agent of candidiasis has increased. In C. albicans, the ability to switch ... However, studies on C. tropicalis morphogenesis are limited. In this minireview, we discuss the regulation of the yeast-hypha ... For decades, Candida albicans has been one of the most prevalent human fungal pathogens, and recently, ... Conserved and Divergent Functions of the cAMP/PKA Signaling Pathway in Candida albicans and Candida tropicalis ...
We evaluated isolates from 344 patients with an initial episode of C. tropicalis candidemia. We found that 58 (16.9%) patients ... Our findings suggest cross-boundary expansion of FNS C. tropicalis and highlight the importance of active surveillance of ... Candida tropicalis is the leading cause of non-C. albicans candidemia in tropical Asia and Latin America. ... were infected by fluconazole-nonsusceptible (FNS) C. tropicalis with cross resistance to itraconazole, voriconazole, and ...
Resistance to flucytosine is rarely described for this species but was observed for 45 (35%) of 130 C. tropicalis isolates ... tropicalis isolates, is widespread in the Paris area. We propose the analysis of 2 polymorphic microsatellite markers coupled ... Candida tropicalis is a diploid ascomycetes yeast responsible for 4%-24% of candidemia. ... Candida tropicalis is a diploid ascomycetes yeast commonly found on the skin and in digestive tracts of healthy human hosts ...
... tropicalis strains with diverse virulences. C. tropicalis exhibited strain-dependent filamentation ability, which was ... tropicalis strains with diverse virulences. C. tropicalis exhibited strain-dependent filamentation ability, which was ... Based on the phenotypes of C. tropicalis in our previous study, we selected nine representative strains with different ... Based on the phenotypes of C. tropicalis in our previous study, we selected nine representative strains with different ...
Candida tropicalis,/italic, and ,italic,Bacillus firmus,/italic,. Disperse dyes are chiefly used by textile industries for the ... Biological decolorization of industrial dyes by Candida .... Biological decolorization of industrial dyes by Candida tropicalis ... Candida tropicalis. and Bacillus firmus. isolated respectively from contaminated soil samples and sludge of a domestic sewage ...
In contrast, we show that in the related pathogen C. tropicalis white cells are capable of sexual mating and that the white- ... We therefore propose that C. tropicalis Wor1 has retained the ancestral role of this family of transcription factors while also ... Despite these differences, switching in both C. tropicalis and C. albicans is dependent on the expression of the Wor1 ... We show that, in addition to regulating the white-opaque switch in C. tropicalis, Wor1 expression also promotes filamentation ...
The particular species involved were Candida parapsilosis, Candida tropicalis, Candida glabrata, Candida krusei, Candida ... Candida krusei, Candida parapsilosis species complex and Candida tropicalis causing invasive candidiasis in China: 3 year ... Candida tropicalis, Candida glabrata species complex and Candida krusei... ... Renal Candida tropicalis abscesses in a patient with acute lymphoblastic leukemia. Li, W.-Y.; Wu, V.-C.; Lin, W.-C.; Chen, Y.-M ...
... and review the literature on Candida osteomyelitis. METHODS: PubMed was searched for cases of Candida osteomyelitis published ... We present a case of bilateral polymicrobial osteomyelitis with Candida tropicalis and Candida krusei, ... OBJECTIVES: We present a case of bilateral polymicrobial osteomyelitis with Candida tropicalis and Candida krusei, and review ... Bilateral polymicrobial osteomyelitis with Candida tropicalis and Candida krusei: a case report and an updated literature ...
C. tropicalis is taxonomically close to C. albicans and shares many pathogenic traits. C. tropicalis is particularly virulent ... Physicians in regions where C. tropicalis is common need to be mindful of this lesser-described pathogen. ... Candida tropicalis is one of the more common Candida causing human disease in tropical countries; the frequency of invasive ... Candida tropicalis in human disease.. @article{Chai2010CandidaTI, title={Candida tropicalis in human disease.}, author={Louis Y ...
  • The n-alkane-assimilating diploid yeast, Candida tropicalis, possesses two acetoacetyl-CoA thiolase (Thiolase I) isozymes encoded by one allele: peroxisomal and cytosolic Thiolase Is encoded by both CT-T1A and CT-T1B. (elsevier.com)
  • Ueda, M , Kanayama, N & Tanaka, A 2000, ' Genetic Evaluation of Peroxisomal and Cytosolic Acetoacetyl-CoA Thiolase Isozymes in n-Alkane-Assimilating Diploid Yeast, Candida tropicalis ', Cell Biochemistry and Biophysics , vol. 32, pp. 285-290. (elsevier.com)
  • We report here on the identification and characterization of novel 2-enoyl thioester reductases of fatty acid metabolism, Etr1p from Candida tropicalis and its homolog Ybr026p (Mrf1′p) from Saccharomyces cerevisiae . (vtt.fi)
  • We report a methodology for the isolation of peroxisome membranes from the yeast Candida tropicalis pK233 grown on oleic acid, and the characterization of the polypeptide and lipid compositions of these membranes. (biologists.org)
  • Aims: The objective of this study was to determine the interactions between common spoilage yeast, Candida tropicalis, isolated from ultrafiltration membranes, and Escherichia coli O157:H7 and Salmonella sp. (conicet.gov.ar)
  • Live cells of phenol-degrading yeast, Candida tropicalis RETL-Cr1, were immobilized on coconut husk and loofah by adsorption. (ums.edu.my)
  • The n-alkane-assimilating diploid yeast, Candida tropicalis, possesses two acetoacetyl-CoA thiolase (Thiolase I) isozymes encoded by one allele: peroxisomal and cytosolic Thiolase Is encoded by both CT-T1A and CT-T1B. (elsevier.com)
  • Ueda, M , Kanayama, N & Tanaka, A 2000, ' Genetic Evaluation of Peroxisomal and Cytosolic Acetoacetyl-CoA Thiolase Isozymes in n-Alkane-Assimilating Diploid Yeast, Candida tropicalis ', Cell Biochemistry and Biophysics , vol. 32, pp. 285-290. (elsevier.com)
  • Continuous treatment of Acid Red B (ARB) with activated sludge (AS) bioaugmented by an azo-degrading yeast Candida tropicalis TL-F1 under aerobic conditions was investigated in the form of sequencing batch tests. (environmental-expert.com)
  • Isolation and partial characterization of catechol 1,2-dioxygenase of phenol degrading yeast Candida tropicalis. (nel.edu)
  • Abstract The purpose of this study was to investigate the production of flavor compounds from olive mill waste by microbial fermentation of Rhizopus oryzae and Candida tropicalis . (bvsalud.org)
  • abstract = "We report here on the identification and characterization of novel 2-enoyl thioester reductases of fatty acid metabolism, Etr1p from Candida tropicalis and its homolog Ybr026p (Mrf1′p) from Saccharomyces cerevisiae. (vtt.fi)
  • Proteogenomics of Candida tropicalis--An Opportunistic Pathogen with Importance for Global Health. (nih.gov)
  • Candida tropicalis is an opportunistic pathogen that causes candidiasis, for example, in immune-compromised individuals, cancer patients, and those who undergo organ transplantation. (nih.gov)
  • The antifungal activity of promethazine against C. tropicalis was investigated by performing time-kill curve assays and assessing rhodamine 6G efflux, cell size/granularity, membrane integrity, and mitochondrial transmembrane potential, through flow cytometry. (deepdyve.com)
  • In conclusion, promethazine presented synergy with azole antifungals against resistant C. tropicalis and exhibited in vitro cytotoxicity against C. tropicalis, altering cell size/granularity, membrane integrity, and mitochondrial function, demonstrating potential mechanisms of cell damage against this yeast species. (deepdyve.com)
  • To our knowledge, this is the first high-throughput proteomics study of C. tropicalis validating predicted protein coding genes and refining the current genome annotation. (nih.gov)
  • Characterization of agglutinin-like sequence genes from non- albicans Candida and phylogenetic analysis of the ALS family. (atcc.org)
  • Reverse transcriptase PCR analysis showed that the ALST3 and SAPT3 genes had the highest expression in their corresponding genes for most C. tropicalis . (frontiersin.org)
  • In this study, the polymorphism and heterogeneity of genes agglutinin-like sequences (ALS)2, Lipase (LIP)1, LIP4, and secretory aspartyl proteinase tropicalis (SAPT)1-4 as well as the relationship between phenotype and genotype were analyzed. (bvsalud.org)
  • ALS 2 and ALS 3 genes were more common in C.tropicalis than ALS 1. (springer.com)
  • Azole-resistant, less susceptible C. tropicalis has emerged worldwide, particularly in the Asia Pacific region ( 5 , 16 - 21 ). (cdc.gov)
  • Candia tropicalis is an increasingly important human pathogen, causing nosocomial fungemia among patients with neutropenia or malignancy. (frontiersin.org)
  • Significance and Impact of the Study: This study support the plausibility that pathogen interactions with strong biofilm forming members of spoilage microbiota, such as C. tropicalis, might play an important role for the survival and dissemination of E. coli O157:H7 and Salmonella sp. (conicet.gov.ar)
  • Nett J, Andes D. Candida albicans biofilm development, modeling a host-pathogen interaction. (springer.com)
  • Candida and invasive mould diseases in non-neutropenic critically ill patients and patients with haematological cancer. (edu.au)
  • Overall, our results supported the view that adhesion and filamentation may play significant roles in the cell damage caused by C. tropicalis . (frontiersin.org)
  • C. tropicalis is particularly virulent in neutropenic hosts commonly with hematogenous seeding to peripheral organs. (semanticscholar.org)
  • You should also be aware of Candida auris , a rare but extremely virulent subspecies of Candida that can be life-threatening in patients with weakened immune system. (thecandidadiet.com)
  • As a result, 1.73-log and 3.23-log cfu/mL increases were observed in the microbial populations of R. oryzae and C. tropicalis during shake cultures , respectively. (bvsalud.org)
  • C. tropicalis can produce a higher concentration of d-limonene from olive mill waste than R. oryzae in shake cultures . (bvsalud.org)
  • The concentration of d-limonene was determined as 185.56 and 249.54 µg/kg in the fermented olive mill waste by R. oryzae and C. tropicalis in shake cultures respectively. (bvsalud.org)
  • In contrast, R. oryzae can produce a higher concentration of d-limonene (87.73 µg/kg) d-limonene than C. tropicalis (11.95 µg/kg) in bioreactor cultures . (bvsalud.org)