A species of bacteria that resemble small tightly coiled spirals. Its organisms are known to cause abortion in sheep and fever and enteritis in man and may be associated with enteric diseases of calves, lambs, and other animals.
Infections with bacteria of the genus CAMPYLOBACTER.
A genus of bacteria found in the reproductive organs, intestinal tract, and oral cavity of animals and man. Some species are pathogenic.
A species of bacteria present in man and many kinds of animals and birds, often causing infertility and/or abortion.
A species of gram-negative, rod-shaped bacteria isolated from the intestinal tract of swine, poultry, and man. It may be pathogenic.
Inflammation of any segment of the SMALL INTESTINE.
An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)
Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.
Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.
A species of thermophilic CAMPYLOBACTER found in healthy seagulls and causing ENTERITIS in humans.
A protein with a molecular weight of 40,000 isolated from bacterial flagella. At appropriate pH and salt concentration, three flagellin monomers can spontaneously reaggregate to form structures which appear identical to intact flagella.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
The presence of bacteria, viruses, and fungi in food and food products. This term is not restricted to pathogenic organisms: the presence of various non-pathogenic bacteria and fungi in cheeses and wines, for example, is included in this concept.
Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (GUILLAIN-BARRE SYNDROME) and POLYRADICULONEUROPATHY, CHRONIC INFLAMMATORY DEMYELINATING. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
Domesticated birds raised for food. It typically includes CHICKENS; TURKEYS, DUCKS; GEESE; and others.
Proteins found in any species of bacterium.
Procedures for identifying types and strains of bacteria. The most frequently employed typing systems are BACTERIOPHAGE TYPING and SEROTYPING as well as bacteriocin typing and biotyping.
An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
Food products manufactured from poultry.
A variant of the GUILLAIN-BARRE SYNDROME characterized by the acute onset of oculomotor dysfunction, ataxia, and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk. The ataxia is produced by peripheral sensory nerve dysfunction and not by cerebellar injury. Facial weakness and sensory loss may also occur. The process is mediated by autoantibodies directed against a component of myelin found in peripheral nerves. (Adams et al., Principles of Neurology, 6th ed, p1313; Neurology 1987 Sep;37(9):1493-8)
The blind sac or outpouching area of the LARGE INTESTINE that is below the entrance of the SMALL INTESTINE. It has a worm-like extension, the vermiform APPENDIX.
Process of determining and distinguishing species of bacteria or viruses based on antigens they share.
Places where animals are slaughtered and dressed for market.
INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER.
A whiplike motility appendage present on the surface cells. Prokaryote flagella are composed of a protein called FLAGELLIN. Bacteria can have a single flagellum, a tuft at one pole, or multiple flagella covering the entire surface. In eukaryotes, flagella are threadlike protoplasmic extensions used to propel flagellates and sperm. Flagella have the same basic structure as CILIA but are longer in proportion to the cell bearing them and present in much smaller numbers. (From King & Stansfield, A Dictionary of Genetics, 4th ed)
A dilated cavity extended caudally from the hindgut. In adult birds, reptiles, amphibians, and many fishes but few mammals, cloaca is a common chamber into which the digestive, urinary and reproductive tracts discharge their contents. In most mammals, cloaca gives rise to LARGE INTESTINE; URINARY BLADDER; and GENITALIA.
Salts and esters of hippuric acid.
A genus of gram-negative, aerotolerant, spiral-shaped bacteria isolated from water and associated with diarrhea in humans and animals.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.
The functional hereditary units of BACTERIA.
Gel electrophoresis in which the direction of the electric field is changed periodically. This technique is similar to other electrophoretic methods normally used to separate double-stranded DNA molecules ranging in size up to tens of thousands of base-pairs. However, by alternating the electric field direction one is able to separate DNA molecules up to several million base-pairs in length.
The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
The edible portions of any animal used for food including domestic mammals (the major ones being cattle, swine, and sheep) along with poultry, fish, shellfish, and game.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Substances that reduce the growth or reproduction of BACTERIA.
Animals which have become adapted through breeding in captivity to a life intimately associated with humans. They include animals domesticated by humans to live and breed in a tame condition on farms or ranches for economic reasons, including LIVESTOCK (specifically CATTLE; SHEEP; HORSES; etc.), POULTRY; and those raised or kept for pleasure and companionship, e.g., PETS; or specifically DOGS; CATS; etc.
Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.
A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
Acute illnesses, usually affecting the GASTROINTESTINAL TRACT, brought on by consuming contaminated food or beverages. Most of these diseases are infectious, caused by a variety of bacteria, viruses, or parasites that can be foodborne. Sometimes the diseases are caused by harmful toxins from the microbes or other chemicals present in the food. Especially in the latter case, the condition is often called food poisoning.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Direct nucleotide sequencing of gene fragments from multiple housekeeping genes for the purpose of phylogenetic analysis, organism identification, and typing of species, strain, serovar, or other distinguishable phylogenetic level.
A broad-spectrum antimicrobial carboxyfluoroquinoline.
The structure of one molecule that imitates or simulates the structure of a different molecule.
The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage.
A species of CAMPYLOBACTER isolated from the INTESTINES of PIGS with proliferative ENTERITIS. It is also found in CATTLE and in CRICETINAE and can cause enteritis in humans.
The expelling of bacteria from the body. Important routes include the respiratory tract, genital tract, and intestinal tract.
Techniques used in studying bacteria.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
A specific monosialoganglioside that accumulates abnormally within the nervous system due to a deficiency of GM1-b-galactosidase, resulting in GM1 gangliosidosis.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
A subclass of ACIDIC GLYCOSPHINGOLIPIDS. They contain one or more sialic acid (N-ACETYLNEURAMINIC ACID) residues. Using the Svennerholm system of abbrevations, gangliosides are designated G for ganglioside, plus subscript M, D, or T for mono-, di-, or trisialo, respectively, the subscript letter being followed by a subscript arabic numeral to indicated sequence of migration in thin-layer chromatograms. (From Oxford Dictionary of Biochemistry and Molecular Biology, 1997)
Any type of abortion, induced or spontaneous, that is associated with infection of the UTERUS and its appendages. It is characterized by FEVER, uterine tenderness, and foul discharge.
A species of CAMPYLOBACTER isolated from cases of human PERIODONTITIS. It is a microaerophile, capable of respiring with OXYGEN.
A technique for identifying individuals of a species that is based on the uniqueness of their DNA sequence. Uniqueness is determined by identifying which combination of allelic variations occur in the individual at a statistically relevant number of different loci. In forensic studies, RESTRICTION FRAGMENT LENGTH POLYMORPHISM of multiple, highly polymorphic VNTR LOCI or MICROSATELLITE REPEAT loci are analyzed. The number of loci used for the profile depends on the ALLELE FREQUENCY in the population.
Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.
Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.
Ability of a microbe to survive under given conditions. This can also be related to a colony's ability to replicate.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
The genetic complement of a BACTERIA as represented in its DNA.
Any aspect of the operations in the preparation, processing, transport, storage, packaging, wrapping, exposure for sale, service, or delivery of food.
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
A family of hemoglobin-like proteins found in BACTERIA; PLANTS; and unicellular eukaryotes. Truncated hemoglobins are distantly related to vertebrate hemoglobins and are typically shorter than vertebrate hemoglobins by 20-40 residues.
The presence of bacteria, viruses, and fungi in water. This term is not restricted to pathogenic organisms.
The white liquid secreted by the mammary glands. It contains proteins, sugar, lipids, vitamins, and minerals.
Substances elaborated by bacteria that have antigenic activity.
An independent state, an archipelago in the western Persian Gulf, northwest of Qatar. It comprises low-lying islands of Bahrain (the largest), Muharraq, Sitra, and several islets. It has extensive oil fields. The name comes from the Arabic al-bahrayn, "the two seas", with reference to its lying in the middle of a bay with its "two seas" east and west of it. (From Webster's New Geographical Dictionary, 1988, p107 & Room, Brewer's Dictionary of Names, 1992, p45)
Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
Animate or inanimate sources which normally harbor disease-causing organisms and thus serve as potential sources of disease outbreaks. Reservoirs are distinguished from vectors (DISEASE VECTORS) and carriers, which are agents of disease transmission rather than continuing sources of potential disease outbreaks.
Large woodland game BIRDS in the subfamily Meleagridinae, family Phasianidae, order GALLIFORMES. Formerly they were considered a distinct family, Melegrididae.
A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that utilizes citrate as a sole carbon source. It is pathogenic for humans, causing enteric fevers, gastroenteritis, and bacteremia. Food poisoning is the most common clinical manifestation. Organisms within this genus are separated on the basis of antigenic characteristics, sugar fermentation patterns, and bacteriophage susceptibility.
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
The science of breeding, feeding and care of domestic animals; includes housing and nutrition.
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
Constituent of 50S subunit of prokaryotic ribosomes containing about 3200 nucleotides. 23S rRNA is involved in the initiation of polypeptide synthesis.

Cloning and expression of the dnaK gene of Campylobacter jejuni and antigenicity of heat shock protein 70. (1/1435)

Campylobacter jejuni is a leading cause of infectious diarrhea throughout the world. In addition, there is growing evidence that Guillain-Barre syndrome, an inflammatory demyelinating disease of the peripheral nervous system, is frequently preceded by C. jejuni infection. In the present study, the hrcA-grpE-dnaK gene cluster of C. jejuni was cloned and sequenced. The dnaK gene consists of an open reading frame of 1,869 bp and encodes a protein with a high degree of homology to other bacterial 70-kDa heat shock proteins (HSPs). The overall percentages of identity to the HSP70 proteins of Helicobacter pylori, Borrelia burgdorferi, Chlamydia trachomatis, and Bacillus subtilis were calculated to be 78.1, 60.5, 57.2, and 53. 8%, respectively. Regions similar to the Escherichia coli sigma70 promoter consensus sequence and to a cis-acting regulatory element (CIRCE) are located upstream of the hrcA gene. Following heat shock, a rapid increase of dnaK mRNA was detectable, which reached its maximum after 20 to 30 min. A 6-His-tagged recombinant DnaK protein (rCjDnaK-His) was generated in E. coli, after cloning of the dnaK coding region into pET-22b(+), and purified by affinity and gel filtration chromatography. Antibody responses to rCjDnaK-His were significantly elevated, compared to those of healthy individuals, in about one-third of the serum specimens obtained from C. jejuni enteritis patients.  (+info)

Physiological characterization of viable-but-nonculturable Campylobacter jejuni cells. (2/1435)

Campylobacter jejuni is a pathogenic, microaerophilic, gram-negative, mesophilic bacterium. Three strains isolated from humans with enteric campylobacteriosis were able to survive at high population levels (10(7) cells ml-1) as viable-but-nonculturable (VBNC) forms in microcosm water. The VBNC forms of the three C. jejuni strains were enumerated and characterized by using 5-cyano-2,3-ditolyl tetrazolium chloride-4',6-diamino-2-phenylindole staining. Cellular volume, adenylate energy charge, internal pH, intracellular potassium concentration, and membrane potential values were determined in stationary-phase cell suspensions after 48 h of culture on Columbia agar and after 1 to 30 days of incubation in microcosm water and compared. A notable increase in cell volume was observed with the VBNC state; the average cell volumes were 1.73 microliter mg of protein-1 for the culturable form and 10.96 microliter mg of protein-1 after 30 days of incubation in microcosm water. Both the internal potassium content and the membrane potential were significantly lower in the VBNC state than in the culturable state. Culturable cells were able to maintain a difference of 0.6 to 0.9 pH unit between the internal and external pH values; with VBNC cells this difference decreased progressively with time of incubation in microcosm water. Measurements of the cellular adenylate nucleotide concentrations revealed that the cells had a low adenylate energy charge (0.66 to 0.26) after 1 day of incubation in microcosm water, and AMP was the only nucleotide detected in the three strains after 30 days of incubation in microcosm water.  (+info)

Evaluation of accuracy and repeatability of identification of food-borne pathogens by automated bacterial identification systems. (3/1435)

The performances of five automated microbial identification systems, relative to that of a reference identification system, for their ability to accurately and repeatedly identify six common food-borne pathogens were assessed. The systems assessed were the MicroLog system (Biolog Inc., Hayward, Calif.), the Microbial Identification System (MIS; MIDI Inc., Newark, Del.), the VITEK system (bioMerieux Vitek, Hazelwood, Mo.), the MicroScan WalkAway 40 system (Dade-MicroScan International, West Sacramento, Calif.), and the Replianalyzer system (Oxoid Inc., Nepean, Ontario, Canada). The sensitivities and specificities of these systems for the identification of food-borne isolates of Bacillus cereus, Campylobacter jejuni, Listeria monocytogenes, Staphylococcus aureus, Salmonella spp., and verotoxigenic Escherichia coli were determined with 40 reference positive isolates and 40 reference negative isolates for each pathogen. The sensitivities of these systems for the identification of these pathogens ranged from 42.5 to 100%, and the specificities of these systems for the identification of these pathogens ranged from 32.5 to 100%. Some of the systems had difficulty correctly identifying the reference isolates when the results were compared to those from the reference identification tests. The sensitivity of MIS for the identification of S. aureus, B. cereus, E. coli, and C. jejuni, for example, ranged from 47.5 to 72. 5%. The sensitivity of the Microlog system for the identification of E. coli was 72.5%, and the sensitivity of the VITEK system for the identification of B. cereus was 42.5%. The specificities of four of the five systems for the identification of all of the species tested with the available databases were greater than or equal to 97.5%; the exception was MIS for the identification of C. jejuni, which displayed a specificity of 32.5% when it was tested with reference negative isolates including Campylobacter coli and other Campylobacter species. All systems had >80% sensitivities for the identification of Salmonella species and Listeria species at the genus level. The repeatability of these systems for the identification of test isolates ranged from 30 to 100%. Not all systems included all six pathogens in their databases; thus, some species could not be tested with all systems. The choice of automated microbial identification system for the identification of a food-borne pathogen would depend on the availability of identification libraries within the systems and the performance of the systems for the identification of the pathogen.  (+info)

Cloning, mutation and distribution of a putative lipopolysaccharide biosynthesis locus in Campylobacter jejuni. (4/1435)

A region encoding ORFs with homology to known lipopolysaccharide (LPS) biosynthesis genes was isolated from two strains of Campylobacter jejuni. One of the strains produces LPS, but the second strain is reported to produce only lipooligosaccharide (LOS) and therefore lacks the O-chain. The two strains shared six predicted ORFs, but an additional ORF, orfE, of unknown function was identified in the LOS-producing strain. Mutation of the shared wbeE (rfbE) homologue (orfF) or deletion of five of the seven genes reduced core reactivity with specific antiserum without affecting O-chain production. Mutation of either the capD homologue (orfG) or the unique orfE had no detectable effect on LOS or LPS production. The presence or absence of orfE in 36 isolates of C. jejuni did not correlate with LOS/LPS phenotype or serotype. However, after insertion of orfE into a LPS-producing orfE-negative strain the O-chain ladder was no longer detectable on Western blots. We were not able to disrupt the wbaP (rfbP) homologue (orfC) in C jejuni.  (+info)

Campylobacter jejuni--an emerging foodborne pathogen. (5/1435)

Campylobacter jejuni is the most commonly reported bacterial cause of foodborne infection in the United States. Adding to the human and economic costs are chronic sequelae associated with C. jejuni infection--Guillian-Barre syndrome and reactive arthritis. In addition, an increasing proportion of human infections caused by C. jejuni are resistant to antimicrobial therapy. Mishandling of raw poultry and consumption of undercooked poultry are the major risk factors for human campylobacteriosis. Efforts to prevent human illness are needed throughout each link in the food chain.  (+info)

The risk of Guillain-Barre syndrome following infection with Campylobacter jejuni. (6/1435)

To estimate the incidence of Guillain-Barre syndrome (GBS) following Campylobacter jejuni infection (CI) we studied three populations where outbreaks of CI had occurred involving an estimated 8000 cases. No case of GBS was detected in the 6 months following the outbreaks in the local populations. The point estimate for the risk of GBS following CI estimated in this study was 0 in 8000 (95% confidence interval 0-3).  (+info)

Detection of cytolethal distending toxin activity and cdt genes in Campylobacter spp. isolated from chicken carcasses. (7/1435)

This study was designed to determine whether isolates from chicken carcasses, the primary source of Campylobacter jejuni and Campylobacter coli in human infections, commonly carry the cdt genes and also whether active cytolethal distending toxin (CDT) is produced by these isolates. Campylobacter spp. were isolated from all 91 fresh chicken carcasses purchased from local supermarkets. Campylobacter spp. were identified on the basis of both biochemical and PCR tests. Of the 105 isolates, 70 (67%) were identified as C. jejuni, and 35 (33%) were identified as C. coli. PCR tests amplified portions of the cdt genes from all 105 isolates. Restriction analysis of PCR products indicated that there appeared to be species-specific differences between the C. jejuni and C. coli cdt genes, but that the restriction patterns of the cdt genes within strains of the same species were almost invariant. Quantitation of active CDT levels produced by the isolates indicated that all C. jejuni strains except four (94%) had mean CDT titers greater than 100. Only one C. jejuni strain appeared to produce no active CDT. C. coli isolates produced little or no toxin. These results confirm the high rate of Campylobacter sp. contamination of fresh chicken carcasses and indicate that cdt genes may be universally present in C. jejuni and C. coli isolates from chicken carcasses.  (+info)

Detection of small numbers of Campylobacter jejuni and Campylobacter coli cells in environmental water, sewage, and food samples by a seminested PCR assay. (8/1435)

A rapid and sensitive assay was developed for detection of small numbers of Campylobacter jejuni and Campylobacter coli cells in environmental water, sewage, and food samples. Water and sewage samples were filtered, and the filters were enriched overnight in a nonselective medium. The enrichment cultures were prepared for PCR by a rapid and simple procedure consisting of centrifugation, proteinase K treatment, and boiling. A seminested PCR based on specific amplification of the intergenic sequence between the two Campylobacter flagellin genes, flaA and flaB, was performed, and the PCR products were visualized by agarose gel electrophoresis. The assay allowed us to detect 3 to 15 CFU of C. jejuni per 100 ml in water samples containing a background flora consisting of up to 8, 700 heterotrophic organisms per ml and 10,000 CFU of coliform bacteria per 100 ml. Dilution of the enriched cultures 1:10 with sterile broth prior to the PCR was sometimes necessary to obtain positive results. The assay was also conducted with food samples analyzed with or without overnight enrichment. As few as +info)

Symptoms of campylobacter infections include:

* Diarrhea (often bloody)
* Fever
* Abdominal pain and cramping
* Nausea and vomiting
* Headache
* Fatigue
* Muscle pain

Transmission of campylobacter infections can occur through the fecal-oral route, contaminated food or water, or direct contact with an infected animal or person. Risk factors for developing a campylobacter infection include eating undercooked poultry, unpasteurized dairy products, and untreated water.

Diagnosis of campylobacter infections typically involves a combination of clinical evaluation, laboratory testing, and medical imaging. Laboratory tests may include culture isolation, polymerase chain reaction (PCR), or immunological assays to detect the presence of Campylobacter bacteria.

Treatment of campylobacter infections typically involves antibiotics such as macrolides, fluoroquinolones, and ceftriaxone. In severe cases, hospitalization may be necessary to manage complications such as dehydration, electrolyte imbalances, or sepsis.

Prevention of campylobacter infections includes proper handling and cooking of food, especially poultry, good hygiene practices, and safe water consumption. Vaccines are also being developed to prevent campylobacter infections in animals and humans.

Overall, campylobacter infections can cause a wide range of illnesses, from mild to severe, and proper diagnosis, treatment, and prevention measures are essential to reduce the risk of complications and death.

Symptoms of enteritis may include diarrhea, abdominal pain, fever, nausea, vomiting, and weight loss. In severe cases, the condition can lead to dehydration, electrolyte imbalances, and even death if left untreated.

The diagnosis of enteritis is typically made through a combination of physical examination, medical history, and diagnostic tests such as endoscopy, imaging studies, and laboratory tests (e.g., blood tests, stool cultures). Treatment depends on the underlying cause of the condition and may include antibiotics, anti-inflammatory medications, and supportive care to manage symptoms.

The symptoms of GBS can range from mild to severe and may include:

* Weakness or tingling sensations in the legs, arms, or face
* Muscle weakness that progresses to paralysis
* Loss of reflexes
* Difficulty swallowing or speaking
* Numbness or pain in the hands and feet
* Fatigue and fever

The diagnosis of GBS is based on a combination of symptoms, physical examination findings, and laboratory tests. There is no cure for GBS, but treatment can help manage symptoms and prevent complications. Plasmapheresis, immunoglobulin therapy, and corticosteroids are common treatments used to reduce inflammation and slow the progression of the disease.

GBS is a rare condition that affects about one in 100,000 people per year in the United States. It can affect anyone, but it is more common in children and young adults. The prognosis for GBS varies depending on the severity of the disease, but most people recover fully within a few weeks or months with proper treatment.

In conclusion, Guillain-Barré Syndrome is a rare autoimmune disorder that can cause muscle weakness and paralysis. While there is no cure for GBS, early diagnosis and treatment can help manage symptoms and prevent complications. With proper care, most people with GBS can recover fully within a few weeks or months.

Some common poultry diseases include:

1. Avian influenza (bird flu): A highly contagious viral disease that affects birds and can be transmitted to humans.
2. Newcastle disease: A viral disease that causes respiratory and gastrointestinal symptoms in birds.
3. Infectious bronchitis: A viral disease that causes respiratory symptoms in birds.
4. Marek's disease: A viral disease that affects the nervous system of birds.
5. Coccidiosis: A parasitic disease caused by the Eimeria protozoa, which can cause diarrhea and weight loss in birds.
6. Chicken anemia virus: A viral disease that causes anemia and weakened immune systems in chickens.
7. Fowl pox: A viral disease that causes skin lesions and other symptoms in birds.
8. Avian encephalomyelitis (AE): A viral disease that affects the brain and spinal cord of birds, causing neurological symptoms such as paralysis and death.
9. Mycoplasmosis: A bacterial disease caused by the Mycoplasma bacteria, which can cause respiratory and other symptoms in birds.
10. Aspergillosis: A fungal disease that affects the respiratory system of birds, causing symptoms such as coughing and difficulty breathing.

Poultry diseases can have a significant impact on bird health and productivity, and can also be transmitted to humans in some cases. It is important for poultry farmers and owners to monitor their flocks closely and take steps to prevent the spread of disease, such as providing clean water and feed, maintaining good hygiene, and vaccinating birds against certain diseases.

There are several types of polyradiculoneuropathy, each with its own set of causes and characteristics:

1. Polyneuropathy: This is the most common type of polyradiculoneuropathy and affects multiple nerves throughout the body. It can be caused by a variety of factors, such as diabetes, vitamin deficiencies, alcoholism, and certain medications.
2. Mononeuritis multiplex: This is a condition in which there is damage to multiple nerves that innervate a specific area of the body, such as the legs or arms. It can be caused by various factors, including diabetes, autoimmune disorders, and certain medications.
3. Radiculoneuropathy: This type of polyradiculoneuropathy affects the nerves that originate from the spinal cord and extend to other parts of the body. It can be caused by compression or inflammation of the nerve roots, such as in the case of herniated discs or spinal stenosis.
4. Autonomic neuropathy: This type of polyradiculoneuropathy affects the nerves that control involuntary functions, such as heart rate, blood pressure, and digestion. It can be caused by a variety of factors, including diabetes, vitamin deficiencies, and certain medications.

The symptoms of polyradiculoneuropathy can vary depending on the specific type and severity of the condition. Common symptoms include:

* Weakness or numbness in the affected areas
* Pain or discomfort in the affected areas
* Difficulty walking or maintaining balance
* Difficulty with fine motor skills, such as buttoning a shirt or tying shoelaces
* Digestive problems, such as constipation or diarrhea
* Urinary incontinence or retention

The diagnosis of polyradiculoneuropathy is typically made based on a combination of physical examination findings, medical history, and results of diagnostic tests such as nerve conduction studies or electromyography. Treatment options for polyradiculoneuropathy depend on the underlying cause of the condition, but may include:

* Medications to manage pain or inflammation
* Physical therapy to improve strength and coordination
* Lifestyle modifications, such as quitting smoking or losing weight, to reduce pressure on the nerves
* Surgery to relieve compression or repair damaged nerves

In some cases, polyradiculoneuropathy may be a symptom of an underlying condition that can be treated or managed with medication or other therapies. It is important to seek medical attention if you experience any symptoms of polyradiculoneuropathy to receive an accurate diagnosis and appropriate treatment.

There are several types of diarrhea, including:

1. Acute diarrhea: This type of diarrhea is short-term and usually resolves on its own within a few days. It can be caused by a viral or bacterial infection, food poisoning, or medication side effects.
2. Chronic diarrhea: This type of diarrhea persists for more than 4 weeks and can be caused by a variety of conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), or celiac disease.
3. Diarrhea-predominant IBS: This type of diarrhea is characterized by frequent, loose stools and abdominal pain or discomfort. It can be caused by a variety of factors, including stress, hormonal changes, and certain foods.
4. Infectious diarrhea: This type of diarrhea is caused by a bacterial, viral, or parasitic infection and can be spread through contaminated food and water, close contact with an infected person, or by consuming contaminated food.

Symptoms of diarrhea may include:

* Frequent, loose, and watery stools
* Abdominal cramps and pain
* Bloating and gas
* Nausea and vomiting
* Fever and chills
* Headache
* Fatigue and weakness

Diagnosis of diarrhea is typically made through a physical examination, medical history, and laboratory tests to rule out other potential causes of the symptoms. Treatment for diarrhea depends on the underlying cause and may include antibiotics, anti-diarrheal medications, fluid replacement, and dietary changes. In severe cases, hospitalization may be necessary to monitor and treat any complications.

Prevention of diarrhea includes:

* Practicing good hygiene, such as washing hands frequently and thoroughly, especially after using the bathroom or before preparing food
* Avoiding close contact with people who are sick
* Properly storing and cooking food to prevent contamination
* Drinking safe water and avoiding contaminated water sources
* Avoiding raw or undercooked meat, poultry, and seafood
* Getting vaccinated against infections that can cause diarrhea

Complications of diarrhea can include:

* Dehydration: Diarrhea can lead to a loss of fluids and electrolytes, which can cause dehydration. Severe dehydration can be life-threatening and requires immediate medical attention.
* Electrolyte imbalance: Diarrhea can also cause an imbalance of electrolytes in the body, which can lead to serious complications.
* Inflammation of the intestines: Prolonged diarrhea can cause inflammation of the intestines, which can lead to abdominal pain and other complications.
* Infections: Diarrhea can be a symptom of an infection, such as a bacterial or viral infection. If left untreated, these infections can lead to serious complications.
* Malnutrition: Prolonged diarrhea can lead to malnutrition and weight loss, which can have long-term effects on health and development.

Treatment of diarrhea will depend on the underlying cause, but may include:

* Fluid replacement: Drinking plenty of fluids to prevent dehydration and replace lost electrolytes.
* Anti-diarrheal medications: Over-the-counter or prescription medications to slow down bowel movements and reduce diarrhea.
* Antibiotics: If the diarrhea is caused by a bacterial infection, antibiotics may be prescribed to treat the infection.
* Rest: Getting plenty of rest to allow the body to recover from the illness.
* Dietary changes: Avoiding certain foods or making dietary changes to help manage symptoms and prevent future episodes of diarrhea.

It is important to seek medical attention if you experience any of the following:

* Severe diarrhea that lasts for more than 3 days
* Diarrhea that is accompanied by fever, blood in the stool, or abdominal pain
* Diarrhea that is severe enough to cause dehydration or electrolyte imbalances
* Diarrhea that is not responding to treatment

Prevention of diarrhea includes:

* Good hand hygiene: Washing your hands frequently, especially after using the bathroom or before preparing food.
* Safe food handling: Cooking and storing food properly to prevent contamination.
* Avoiding close contact with people who are sick.
* Getting vaccinated against infections that can cause diarrhea, such as rotavirus.

Overall, while diarrhea can be uncomfortable and disruptive, it is usually a minor illness that can be treated at home with over-the-counter medications and plenty of fluids. However, if you experience severe or persistent diarrhea, it is important to seek medical attention to rule out any underlying conditions that may require more formal treatment.

The syndrome is named after the doctors who first described it in the 1950s, Drs. Miller and Fisher. It is characterized by a gradual onset of muscle weakness and wasting, which typically begins in the hands and feet and spreads to other parts of the body over time.

Other symptoms of Miller Fisher Syndrome may include:

* Muscle cramps
* Muscle spasms
* Twitching of the eyelids (blepharospasm)
* Loss of reflexes
* Difficulty with speech and swallowing
* Weakness in the muscles of the face, arms, and legs
* Atrophy of the muscles in the hands and feet

The exact cause of Miller Fisher Syndrome is not known, but it is believed to be related to a problem with the nerve cells that control voluntary muscle movement. The disorder usually affects adults between the ages of 50 and 70, and men are more commonly affected than women.

There is no cure for Miller Fisher Syndrome, but treatment can help manage the symptoms. Physical therapy, occupational therapy, and medications such as anticonvulsants and muscle relaxants may be used to improve muscle strength and function. In severe cases, a ventilator may be needed to assist with breathing.

The progression of Miller Fisher Syndrome can vary widely, and some people may experience a rapid decline in muscle function while others may remain relatively stable for many years. The life expectancy of individuals with the disorder is generally reduced due to the risk of complications such as respiratory failure and pneumonia.

Gastroenteritis can be classified into different types based on the cause:

Viral gastroenteritis - This is the most common type of gastroenteritis and is caused by norovirus or rotavirus.

Bacterial gastroenteritis - This type is caused by bacteria such as salmonella, E. coli, or campylobacter.

Parasitic gastroenteritis - This is caused by parasites such as giardia or cryptosporidium.

Foodborne gastroenteritis - This type is caused by consuming contaminated food or water.

Gastroenteritis can be treated with antibiotics for bacterial infections, anti-diarrheal medications, and hydration therapy to prevent dehydration. In severe cases, hospitalization may be necessary.

Prevention measures include proper hand washing, avoiding close contact with people who are sick, and avoiding contaminated food and water. Vaccines are also available for some types of gastroenteritis such as rotavirus.

Foodborne diseases, also known as food-borne illnesses or gastrointestinal infections, are conditions caused by eating contaminated or spoiled food. These diseases can be caused by a variety of pathogens, including bacteria, viruses, and parasites, which can be present in food products at any stage of the food supply chain.

Examples of common foodborne diseases include:

1. Salmonella: Caused by the bacterium Salmonella enterica, this disease can cause symptoms such as diarrhea, fever, and abdominal cramps.
2. E. coli: Caused by the bacterium Escherichia coli, this disease can cause a range of symptoms, including diarrhea, urinary tract infections, and pneumonia.
3. Listeria: Caused by the bacterium Listeria monocytogenes, this disease can cause symptoms such as fever, headache, and stiffness in the neck.
4. Campylobacter: Caused by the bacterium Campylobacter jejuni, this disease can cause symptoms such as diarrhea, fever, and abdominal cramps.
5. Norovirus: This highly contagious virus can cause symptoms such as diarrhea, vomiting, and stomach cramps.
6. Botulism: Caused by the bacterium Clostridium botulinum, this disease can cause symptoms such as muscle paralysis, respiratory failure, and difficulty swallowing.

Foodborne diseases can be diagnosed through a variety of tests, including stool samples, blood tests, and biopsies. Treatment typically involves antibiotics or other supportive care to manage symptoms. Prevention is key to avoiding foodborne diseases, and this includes proper food handling and preparation practices, as well as ensuring that food products are stored and cooked at safe temperatures.

Abortion, Septic: A potentially life-threatening complication of an abortion procedure that occurs when bacteria enter the uterus and cause infection. Symptoms may include fever, chills, abdominal pain, nausea, vomiting, and vaginal discharge with a foul odor. Septic abortion can be caused by poor surgical technique, contamination of instruments, or failure to use sterile equipment. Treatment may involve antibiotics, surgical drainage of the infection, and supportive care. In severe cases, hospitalization and intensive care may be necessary to manage the infection and prevent complications such as sepsis or shock.

The term "septic abortion" is used to describe an abortion that has become infected, usually as a result of poor surgical technique or contamination during the procedure. This type of infection can be serious and potentially life-threatening, so it is important for women who have had an abortion to seek medical attention immediately if they experience any symptoms of infection.

Symptoms of septic abortion may include fever, chills, abdominal pain, nausea, vomiting, and vaginal discharge with a foul odor. In severe cases, women may develop sepsis or shock, which can be fatal if not treated promptly.

Treatment for septic abortion typically involves antibiotics to clear the infection, as well as surgical drainage of any abscesses that have formed in the uterus or other pelvic tissues. In some cases, hospitalization and intensive care may be necessary to manage the infection and prevent complications.

Preventing septic abortion is important, and this can be achieved by ensuring that proper surgical technique is used during the abortion procedure, using sterile equipment and supplies, and providing adequate aftercare to women who have had an abortion. Women who have had an abortion should seek medical attention immediately if they experience any symptoms of infection, as prompt treatment can help prevent serious complications and improve outcomes.

"Campylobacter jejuni , Campylobacter Food Poisoning". www.about-campylobacter.com. Retrieved 2016-04-18. Gundogdu, Ozan; Wren, ... funded by NIAID Current research on Campylobacter jejuni at the Norwich Research Park Type strain of Campylobacter jejuni at ... C. jejuni is commonly associated with poultry, and is also commonly found in animal feces. Campylobacter is a helical-shaped, ... Campylobacter means "curved rod", deriving from the Greek kampylos (curved) and baktron (rod). Of its many species, C. jejuni ...
Campylobacter jejuni (causes gastroenteritis); Lysinibacillus sphaericus (previously termed Bacillus sphaericus, a rare cause ...
Campylobacter fetus, Campylobacter hyointestinalis subsp. hyointestinalis, Campylobacter jejuni, Campylobacter lari and ... C. upsaliensis is the second most common Campylobacter species isolated in humans with diarrhea (behind Campylobacter jejuni). ... "Routine identification of Campylobacter jejuni and Campylobacter coli from human stool samples". FEMS Microbiology Letters. 179 ... Other Campylobacter species (C. jejuni) have been clearly linked to causing Guillain-Barre Syndrome, an autoimmune disorder ...
Here she specialised in retrovirology and protection against infection caused by the bacteria Campylobacter jejuni. After ... Protection against Campylobacter jejuni infection. london.ac.uk (PhD thesis). University of London. OCLC 940318607. Science, ...
At least a dozen species of Campylobacter have been implicated in human disease, with C. jejuni (80-90%) and C. coli (5-10%) ... When exposed to atmospheric oxygen, C. jejuni is able to change into a coccus form. Most species of Campylobacter are positive ... The genomes of several Campylobacter species have been sequenced, beginning with C. jejuni in 2000. These genome studies have ... Davies E, Ebbesen M, Johansson C, Kaden R, Rautelin H (2020). "Genomic and Phenotypic Characterisation of Campylobacter jejuni ...
The order Campylobacterales includes human pathogens such as Helicobacter pylori and Campylobacter jejuni. The only publicly ... "Bad Bug Book - BBB - Campylobacter jejuni". www.fda.gov. Retrieved 2016-04-03. "Helicobacter Pylori Infections: MedlinePlus". ...
However, Campylobacter jejuni has seven protofilaments. The basal body has several traits in common with some types of ...
Monteville MR, Yoon JE, Konkel ME (January 2003). "Maximal adherence and invasion of INT 407 cells by Campylobacter jejuni ... Black RE, Levine MM, Clements ML, Hughes TP, Blaser MJ (March 1988). "Experimental Campylobacter jejuni infection in humans". ... Whitehouse CA, Balbo PB, Pesci EC, Cottle DL, Mirabito PM, Pickett CL (May 1998). "Campylobacter jejuni cytolethal distending ... Zilbauer M, Dorrell N, Wren BW, Bajaj-Elliott M (February 2008). "Campylobacter jejuni-mediated disease pathogenesis: an update ...
She also edited one book in 1992 titled Campylobacter Jejuni: Current Status and Future Trends. The genus Campylobacter is a ... Nachamkin, Irving; Blaser, Martin J.; Tompkins, Lucy S. (1992). Campylobacter Jejuni: Current Status and Future Trends. ISBN ...
Campylobacter jejuni, another gastrointestinal tract commensal of ruminants, is another important cause of abortion in ewes. ... Acheson, D.; Allos, B. M. (15 April 2001). "Campylobacter jejuni Infections: Update on Emerging Issues and Trends". Clinical ... Campylobacter fetus is a rod-shaped, gram-negative species of bacteria within the genus Campylobacter of phylum Pseudomonadota ... Type strain of Campylobacter fetus subsp. fetus at BacDive - the Bacterial Diversity Metadatabase Type strain of Campylobacter ...
Campylobacter jejuni is one of the most common sources of infectious enteritis, and the most common bacterial pathogen found in ... Peterson, Michael C. (2003-05-01). "Campylobacter jejuni enteritis associated with consumption of raw milk". Journal of ... In particular, campylobacter, shigella, salmonella and many other bacteria induce acute self-limited colitis, an inflammation ... In Germany, 90% of cases of infectious enteritis are caused by four pathogens, Norovirus, Rotavirus, Campylobacter and ...
Relationship to Campylobacter jejuni infection and anti-glycolipid antibodies". Brain. 118 (3): 597-605. doi:10.1093/brain/ ... A link to Campylobacter jejuni was suspected when a young girl was admitted to Second Teaching Hospital. She had become ill ... Investigators discovered that several of the chickens in the home displayed similar symptoms and C. jejuni was found in their ... Several of the paralysis patients were found to have antibodies to C. jejuni and anti-GD1a antibodies, suggesting a link ...
Campylobacter jejuni. Campylobacter jejuni-associated disease is more prevalent in individuals who express human leukocyte ... Campylobacter jejuni is detected in these lesions by immunostaining. Patients with this disease commonly have a monoclonal ... Immunostaining of small bowel lesions in these cases commonly detects the presence of Campylobacter jejuni and is predictive ... These lesions localizes to the duodenum, jejunum, or ilium in about 63, 17, and 8% of cases, respectively, or involve more than ...
... is a form of agar used to culture species of Brucella and Campylobacter jejuni Mangels JI, Douglas BP (October ... Reeser RJ, Medler RT, Billington SJ, Jost BH, Joens LA (2007). "Characterization of Campylobacter jejuni biofilms under defined ...
Avrain L, Vernozy-Rozand C, Kempf I (2004). "Evidence for natural horizontal transfer of tetO gene between Campylobacter jejuni ... between Campylobacter jejuni. Neochrome, a gene in some ferns that enhances their ability to survive in dim light. Believed to ...
"Bickerstaff's brainstem encephalitis after an outbreak of Campylobacter jejuni enteritis". Journal of Neuroimmunology. Beltz, ...
The bacterium Campylobacter jejuni has been isolated from their beaks and cloacae so milk can become contaminated as they drink ... "Jackdaws as potential source of milk-borne Campylobacter jejuni infection". The Lancet. 335 (8698): 1160. doi:10.1016/0140-6736 ... This activity was linked to cases of Campylobacter gastroenteritis in Gateshead in northeast England and led the Department of ...
The preponderance of reported milk borne diseases arises from Campylobacter, most notably the strains C. jejuni and C. coli. ... Phongsisay, Vongsavanh (April 2016). "The immunobiology of Campylobacter jejuni: Innate immunity and autoimmune diseases". ... "Symptoms , Campylobacter , CDC". www.cdc.gov. 2019-12-23. Retrieved 2022-03-22. "Guillain-Barré Syndrome , Campylobacter , CDC ... Campylobacter is implicated in more than 80% of reported American disease outbreaks in relevance with raw milk from 2007 to ...
... heptacis-undecaprenol This enzyme is isolated from Campylobacter jejuni. Glover KJ, Weerapana E, Imperiali B (October 2005). " ... "Polyisoprenol specificity in the Campylobacter jejuni N-linked glycosylation pathway". Biochemistry. 46 (50): 14342-8. doi: ...
During her doctorate, she studied Mycobacterium tuberculosis and Campylobacter jejuni. In 2001, Allen-Vercoe moved to Canada, ...
CampyShield targets Campylobacter jejuni and Campylobacter coli which cause campylobacteriosis. Used to treat raw red med (e.g ...
Gastrointestinal campylobacteriosis is caused by Campylobacter jejuni or Campylobacter coli. Although it is a commensal in the ... Campylobacter is spread horizontally via the fecal-oral route. Campylobacter fetus can also cause venereal disease and abortion ... jejuni can be treated with the antibiotics erythromycin and tetracycline. The disease can be prevented with good husbandry and ... Campylobacter infection can be confirmed by rising antibody titers, culture on a selective medium, or histological examination ...
"Colonization of cattle intestines by Campylobacter jejuni and Campylobacter lanienae". Applied and Environmental Microbiology. ... Campylobacter lanienae is a species of Campylobacter found in humans and other animals. Like other Campylobacter species, it is ... "Campylobacter lanienae" at the Encyclopedia of Life Type strain of Campylobacter lanienae at BacDive - the Bacterial Diversity ... Logan, J.; Burnens, A.; Linton, D.; Lawson, A. J.; Stanley, J. (2000). "Campylobacter lanienae sp. nov., a new species isolated ...
2007). "A proteome-wide protein interaction map for Campylobacter jejuni". Genome Biol. 8 (7): R130. doi:10.1186/gb-2007-8-7- ...
"Reactive nitrogen species contribute to innate host defense against Campylobacter jejuni". Infection and Immunity. 76 (3): 986- ...
... and Campylobacter jejuni. Common viral contaminants include norovirus, sapovirus, rotavirus, enteroviruses, and hepatitis A and ...
Campylobacter jejuni genomes and related information at PATRIC, a Bioinformatics Resource Center funded by NIAID (Wikipedia ... Campylobacteriosis is an infection by the Campylobacter bacterium, most commonly C. jejuni. It is among the most common ... Furthermore, in the United Kingdom during 2000, Campylobacter jejuni was involved in 77.3% in all cases of laboratory confirmed ... C jejuni appears to achieve this by invading and destroying epithelial cells.[citation needed] C. jejuni can also cause a ...
McSweegan, E; Walker, R I (1986). "Identification and characterization of two Campylobacter jejuni adhesins for cellular and ... He published research on the disease-causing mechanisms of the bacteria Campylobacter jejuni and Enterotoxigenic Escherichia ...
"Identification and characterization of NeuB3 from Campylobacter jejuni as a pseudaminic acid synthase". The Journal of ...
November 2002). "N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli". Science. 298 (5599 ... as glycosylation for stability or function have been expressed using the N-linked glycosylation system of Campylobacter jejuni ...
In 1912 and 1915, Roosevelt had illnesses compatible with Campylobacter jejuni, a major causative agent of GBS.: 455 It has ...
The hisB gene, found in the enterobacteria (such as E. coli), in Campylobacter jejuni and in Xylella/Xanthomonas encodes a ...
H7 Shigella Salmonella Campylobacter jejuni Hemorrhoids Neoplasm - such as colorectal cancer Angiodysplasia Bleeding from a ... it can also occur in either the duodenum and jejunum, and occasionally the portions of the small intestine and proximal colon. ... the aforementioned parts of the intestine and also included the last 1/4 of the duodenum and the entire area of the jejunum and ...
... hydrophila Bacillus brevis Bacillus cereus Bacillus megaterium Bacillus subtilis Burkholderia cepacia Campylobacter jejuni ...
2009). Affinity probe capillary electrophoresis evaluation of aptamer binding to Campylobacter jejuni bacteria(ARL-TR (Aberdeen ...
Campylobacter jejuni is not competent until the exogenous genetic material is confirmed by the cell to be Campylobacter jejuni ... Factors Regulating Competence Development and DNA Uptake in Campylobacter jejuni". International Journal of Molecular Sciences ...
... heptacis-undecaprenol This enzyme is isolated from Campylobacter jejuni. Glover KJ, Weerapana E, Imperiali B (October 2005). " ...
... an N-acetyltransferase from the bacillosamine synthetic pathway required for N-glycan synthesis in Campylobacter jejuni". ... diacetylbacillosamine by enzymes of the Campylobacter jejuni general protein glycosylation system". Biochemistry. 45 (45): ... "Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing ...
Most common bacterial foodborne pathogens are: Campylobacter jejuni which can lead to secondary Guillain-Barré syndrome and ... The United Kingdom, in 2000, reported the individual bacteria involved as the following: Campylobacter jejuni 77.3%, Salmonella ... Humphrey T, O'Brien S, Madsen M (July 2007). "Campylobacters as zoonotic pathogens: a food production perspective". ... Asymptomatic subclinical infection may help spread these diseases, particularly Staphylococcus aureus, Campylobacter, ...
"The Crystal Structure of a Complex of Campylobacter jejuni dUTPase with Substrate Analogue Sheds Light on the Mechanism and ...
... used to reconstruct the contribution of different environmental and livestock reservoirs of the bacteria Campylobacter jejuni ...
"Alternative spermidine biosynthetic route is critical for growth of Campylobacter jejuni and is the dominant polyamine pathway ...
... diacetylbacillosamine by enzymes of the Campylobacter jejuni general protein glycosylation system". Biochemistry. 45 (45): ... "Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing ...
The diarrhea-causing bacteria Campylobacter jejuni is also a reported cause of transverse myelitis. Other associated causes ...
Epsilon toxin of Clostridium perfringens Food-borne and Water-borne Pathogens Bacteria Campylobacter jejuni Diarrheagenic E. ...
Campylobacter jejuni, a cause of gastroenteritis, is spread by the fecal-oral route from animals, or by eating insufficiently ...
... more than one hundred inmates and staff at the Washington State Penitentiary were infected with Campylobacter jejuni. During ... Campylobacter Outbreak - Washington State Penitentiary "Food issues run deep at Washington State Penitentiary". Sax, Sarah. " ...
... diphosphate This enzyme is isolated from the bacteria Legionella pneumophila and Campylobacter jejuni. Glaze PA, Watson DC, ... "The CMP-legionaminic acid pathway in Campylobacter: biosynthesis involving novel GDP-linked precursors". Glycobiology. 19 (7): ...
1995). "Ganglioside-like epitopes of lipopolysaccharides from Campylobacter jejuni (PEN 19) in three isolates from patients ... Campylobacter jejuni and Mycoplasma pneumoniae. Antibodies to a GM1 epitope as well as to one with the GT1a or GD3 epitope were ... jejuni infection. Many studies indicate that C. jejuni may be causative for a subset of some forms of neuropathies. Antibodies ... "Anti-ganglioside GM1 antibodies in Guillain-Barré syndrome and their relationship to Campylobacter jejuni infection". Ann. ...
... and Campylobacter jejuni (most common cause of food poisoning). He and his research group discovered a number of bacterial ... He also holds numerous patents for anti-Campylobacter agents and meningococcal vaccine candidates. He was chairman or member of ...
Experimental Campylobacter jejuni infection in humans. J Infect Dis 1988;157:472-9. CrossRef PubMed ... Humphrey TJ, Beckett P. Campylobacter jejuni in dairy cows and raw milk. Epidemiol Infect 1987;98:263-9. CrossRef PubMed ... Campylobacter jejuni is a common raw milk contaminant and is notoriously difficult to isolate from food products, because of ... Campylobacter jejuni Infections Associated with Raw Milk Consumption - Utah, 2014. Weekly / April 1, 2016 / 65(12);301-305 ...
Campylobacter jejuni is one of the most common bacterial ... Campylobacter jejuni is one of the most common bacterial causes ... Campylobacter jejuni infection causes cramping, diarrhea, abdominal pain and fever within 2 to 5 days after a person has been ... Campylobacter jejuni infection causes cramping, diarrhea, abdominal pain and fever within 2 to 5 days after a person has been ... Most cases of Campylobacter jejuni come from handling or ingesting raw or undercooked poultry meat. Although poultry and other ...
Salmonella and Campylobacter in chicken meat: meeting report  World Health Organization; Food and Agriculture Organization of ... Report of the WHO consultation on veterinary public health aspects of prevention and control of campylobacter infections, ...
Campylobacter Fetus-Jejuni Bacterin (Colorado), 50 mL Item #888187 , Weight 0.16 lbs ... Campylobacter Fetus-Jejuni Bacterin (Colorado), 250 mL Item #888188 , Weight 0.66 lbs ...
Chemoenzymatic Synthesis of Campylobacter jejuni Lipo-oligosaccharide Core Domains to Examine Guillain-Barré Syndrome Serum ... Chemoenzymatic Synthesis of Campylobacter jejuni Lipo-oligosaccharide Core Domains to Examine Guillain-Barré Syndrome Serum ...
Campylobacter jejuni is a microaerophilic zoonotic pathogen with an atypical respiratory Complex I that oxidizes a flavodoxin ( ... The flavodoxin FldA activates the class 1a ribonucleotide reductase of Campylobacter jejuni ... The flavodoxin FldA activates the class 1a ribonucleotide reductase of Campylobacter jejuni. Molecular Microbiology, 116 (1). ... jejuni possesses a single class Ia-type (Fe) RNR (NrdAB) that would be expected to be ferredoxin dependent. We show that CjFldA ...
Campylobacter jejuni : current status and future trends / editors, Irving Nachamkin, Martin J. Blaser, Lucy S. Tompkins. ... Campylobacter jejuniNLM classification: QW 154 Tags from this library: No tags from this library for this title. Log in to add ...
... Creator Griekspoor, Petra; ... Background: The zoonotic bacterium Campylobacter jejuni has a broad host range but is especially associated with birds, both ... Campylobacter jejuni sequence types show remarkable spatial and temporal stability in blackbirds. ... jejuni genotypes. Conclusion: The maintenance of host-specific signals in spatially and temporally separated C. jejuni ...
Use of Comparative Genomics and an In Vitro Screening Approach to Identify Vaccine Candidates for Campylobacter Jejuni ... Interventions to control and reduce the incidence of Campylobacter jejuni colonization in poultry is important in order to ... Home Poultry Facts Health Use of comparative genomics to identify vaccine candidates for Campylobacter Jejuni ... Use of comparative genomics to identify vaccine candidates for Campylobacter Jejuni. 13 July 2022. 54 ...
Genomic epidemiology of Campylobacter jejuni associated with asymptomatic pediatric infection in the Peruvian Amazon by: Ben ... Genomic epidemiology of Campylobacter jejuni associated with asymptomatic paediatric infection in the Peruvian Amazon by: Ben ... Domestication of Campylobacter jejuni NCTC 11168 by: Ben Pascoe, et al. Published: (2019) ... Agricultural intensification and the evolution of host specialism in the enteric pathogen Campylobacter jejuni Evangelos ...
Spatio-temporal epidemiology of Campylobacter jejuni enteritis, in an area of Northwest England, 2000-2002 ... Spatio-temporal epidemiology of Campylobacter jejuni enteritis, in an area of Northwest England, 2000-2002 ...
Septic arthritis, also known as infectious arthritis, may represent a direct invasion of joint space by various microorganisms, most commonly caused by a variety of bacteria .However, viruses, mycobacteria, and fungi have been implicated.
a Aeromonas (one outbreak). b Clostridium perfringens (one outbreak); Campylobacter jejuni (two outbreaks). c Burkholderia ...
Development of Inhibitors to a Bacterial Amino-Sugar Acetyltransferase from Campylobacter jejuni ... ICCampylobacter jejuniTargeting Bacillosamine BiosynthesisBacterial Amino-Sugar Acetyltransferaseamino-sugar acetyltransferase ... involved in biosynthesis of UDP-diNAcBac in Campylobacter jejuni. Herein we report optimization of the hits into potent small ... Development of Inhibitors to a Bacterial Amino-Sugar Acetyltransferase from Campylobacter jejuni. ...
Developing an epidemiologically robust typing approach to identify, describe and trace outbreaks of Campylobacter jejuni ... Developing an epidemiologically robust typing approach to identify, describe and trace outbreaks of Campylobacter jejuni ...
Campylobacter jejuni / genetics* * Clustered Regularly Interspaced Short Palindromic Repeats * Dependovirus / genetics* * Gene ...
Diversity of Campylobacter jejuni and Campylobacter coli Genotypes from Human and Animal Sources from Rio de Janeiro, Brazil ... PCR-fingerprinting of Campylobacter jejuni and Campylobacter coli isolates by using Enterobacterial Repetitive Intergenic ... PCR-fingerprinting of Campylobacter jejuni and Campylobacter coli isolates by using Enterobacterial Repetitive Intergenic ... Antimicrobial resistance and plasmid profiles of Campylobacter jejuni and Campylobacter coli from human and animal sources ...
Campylobacter jejuni is a leading cause of food-borne disease worldwide. The pathogenicity of C. jejuni is closely associated ... Recruitment of LC3 by Campylobacter jejuni to bacterial invasion site on host cells via the Rac1-mediated signaling pathway ... Recruitment of LC3 by Campylobacter jejuni to bacterial invasion site on host cells via the Rac1-mediated signaling pathway ... C. jejuni infection induced LC3-II conversion, and autophagy induction facilitated C. jejuni internalization. Also, autophagy ...
Campylobacter jejuni Citrobacter koseri Citrobacter freundii Enterobacter cloacae Escherichia coli Haemophilus influenzae ... Campylobacter jejuni, Shigella boydii†, Shigella dysenteriae, Shigella flexneri or Shigella sonnei† when antibacterial therapy ...
Scanning electron microscope image of Campylobacter jejuni.. New Campylobacter-Detecting Medium Licensed ... The new culture medium, called Campy-Cefex, is specifically designed to detect and differentiate C. jejuni and C. coli mixtures ... A quicker, simpler way to distinguish between Campylobacter species has now been licensed for manufacture by two U.S. companies ... Campy-Cefex selects for Campylobacter among competing flora in a sample, cultivating colonies that resemble tiny water droplets ...
Survival of inoculated Campylobacter jejuni and Escherichia coli O157:H7 on kale during refrigerated storage. ... Campylobacter and pathogenic Escherichia coli illnesses have been attributed to the consumption of fresh produce. The leafy ...
Comparative gene analysis of stress susceptible and tolerant Campylobacter jejuni. Publikation: Konferencebidrag › Poster › ...
Distribución de biovares de Campylobacter jejuni ssp. jejuni y Campylobacter coli en monos de Iquitos (Perú). TRESIERRA-AYALA, ...
Species: Campylobacter jejuni subsp. jejuni [TaxId:407148]. Gene: C8J_1081. Database cross-references and differences (RAF- ... Species: Campylobacter jejuni subsp. jejuni [TaxId:407148]. Gene: C8J_1081. Database cross-references and differences (RAF- ...
Categories: Campylobacter jejuni Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
Pet Store Puppies in the US Linked to Extensively Drug-Resistant Campylobacter jejuni Infections ...
Campylobacter jejuni as a case study. Interna- tional Journal of Food Microbiology, 157(2):182-188. ...
  • Genomic epidemiology of Campylobacter jejuni associated with asymptomatic pediatric infection in the Peruvian Amazon by: Ben Pascoe, et al. (swan.ac.uk)
  • Additional cases of C. jejuni infection were identified in October, and UDAF permanently revoked dairy A's permit to sell raw milk on December 1. (cdc.gov)
  • During May 9-November 6, 2014, a total of 99 cases of C. jejuni infection were identified. (cdc.gov)
  • On May 21, 2014, UPHL notified UDOH of three laboratory-confirmed cases (in patients A, B, and C) of C. jejuni infection with indistinguishable SmaI PFGE patterns (DBRS16.0196). (cdc.gov)
  • Campylobacter infection is a reportable disease in Utah, and all Campylobacter isolates undergo PFGE analysis ( 1 ). (cdc.gov)
  • A confirmed case was defined as the onset of diarrheal illness caused by C. jejuni matching the cluster PFGE pattern or confirmed Campylobacter infection on or after May 1 in a person who had consumed dairy A raw milk 1-10 days before illness onset. (cdc.gov)
  • Campylobacter jejuni infection causes cramping, diarrhea, abdominal pain and fever within 2 to 5 days after a person has been exposed to the organism. (medlineplus.gov)
  • The outcomes could also help reduce the concern for human health and economic burden incurred by C. jejuni infection. (zootecnicainternational.com)
  • But autophagy involvement as a host immune response to C. jejuni infection has not been clarified. (tokushima-u.ac.jp)
  • This study revealed autophagy association in C. jejuni infection. (tokushima-u.ac.jp)
  • During infection, C. jejuni activated the Rho family small GTPase Rac1 signaling pathway, which modulates actin remodeling and promotes the internalization of this pathogen. (tokushima-u.ac.jp)
  • Interestingly, during C. jejuni invasion, LC3 was recruited to bacterial entry site depending on Rac1 GTPase activation just at the early step of the infection. (tokushima-u.ac.jp)
  • C. jejuni infection induced LC3-II conversion, and autophagy induction facilitated C. jejuni internalization. (tokushima-u.ac.jp)
  • Infection with C. jejuni is the most commonly identified antecedent to Guillain-Barré Syndrome, an autoimmune peripheral neuropathy. (cdc.gov)
  • a Campylobacter -positive puppy was identified as a potential source of infection. (who.int)
  • Methods: The host specificity and temporal stability of European Blackbird C. jejuni was investigated with multilocus sequence typing in a set of isolates collected from Sweden, Australia, and The Azores. (edu.au)
  • We report a rising trend in ofloxacin resistance, re-emergence of erythromycin resistance and indications of co-resistance to both drugs in clinical isolates of Campylobacter spp. (who.int)
  • Ciprofloxacin is effective in treating infectious diarrheas caused by E. coli, Campylobacter jejuni, and shigella bacteria. (medicinenet.com)
  • While a majority of Campylobacter infections are mild self-limiting diarrhoeal illnesses, in a proportion of cases severe infections occur, including prolonged enteritis, septicaemia and other extraintestinal infections [4]. (who.int)
  • In addition to laboratory-confirmed infections in people, a Campylobacter -positive faecal sample was recovered from the puppy. (who.int)
  • Ongoing Outbreak of Extensively Drug-Resistant Campylobacter jejuni Infections Associated With US Pet Store Puppies, 2016-2020. (cdc.gov)
  • IMPORTANCE: Extensively drug-resistant Campylobacter jejuni infections cannot be treated with any commonly recommended antibiotics and pose an increasing public health threat. (cdc.gov)
  • OBJECTIVES: To investigate cases of extensively drug-resistant C jejuni associated with pet store puppies and describe the epidemiologic and laboratory characteristics of these infections. (cdc.gov)
  • DESIGN, SETTING, AND PARTICIPANTS: In August 2017, health officials identified, via survey, patients with C jejuni infections who reported contact with puppies sold by pet stores. (cdc.gov)
  • In conjunction with state and federal partners, the Centers for Disease Control and Prevention investigated cases of culture-confirmed C jejuni infections in US patients with an epidemiologic or molecular association with pet store puppies between January 1, 2016, and February 29, 2020. (cdc.gov)
  • Campylobacter is the most commonly notified cause of gastroenteritis in Australia, but few outbreaks are identified relative to disease incidence. (who.int)
  • Between 24 April and 25 June 2012, two outbreaks of Campylobacter gastroenteritis occurred at an Australian residential aged-care facility (ACF) ( Figure 1 ). (who.int)
  • Campylobacter jejuni is a microaerophilic zoonotic pathogen with an atypical respiratory Complex I that oxidizes a flavodoxin (FldA) instead of NADH. (uea.ac.uk)
  • Background: The zoonotic bacterium Campylobacter jejuni has a broad host range but is especially associated with birds, both domestic and wild. (edu.au)
  • Host ecology regulates interspecies recombination in bacteria of the genus Campylobacter by: Matthew Hitchings, et al. (swan.ac.uk)
  • Se sabe que los organismos causan aborto en ovejas y fiebre y enteritis en el hombre y pueden asociarse con enfermedades entéricas en terneros, ovejas y otros animales. (bvsalud.org)
  • Le taux d'isolement était plus élevé en été, sauf pour Yersinia spp. (who.int)
  • Specific objectives for this research study included, 1) to predict the protein-coding regions of isolated Campylobacter strains by analyzing the complete genome sequences, 2) to identify vaccine candidates against C. jejuni via computer simulation, and 3) to evaluate the feasibility of the antigens as vaccine candidate using in vitroscreening approach. (zootecnicainternational.com)
  • Multiple genome sequences of C. jejuni strains isolated from different poultry sources (e.g., retail meat, cloacal swab, and litter samples) were compared. (zootecnicainternational.com)
  • A total of six antigens were predicted based on the whole genome sequences of C. jejuni . (zootecnicainternational.com)
  • Essential genome of Campylobacter jejuni. (cdc.gov)
  • List of C. jejuni strains included in MLSA analysis. (cdc.gov)
  • V. cholerae, Yersinia enterocolitica and Campylobacter jejuni were not detected in this study. (frontiersin.org)
  • In May 2014, the Utah Public Health Laboratory (UPHL) notified the Utah Department of Health (UDOH) of specimens from three patients infected with Campylobacter jejuni yielding indistinguishable pulsed-field gel electrophoresis (PFGE) patterns. (cdc.gov)
  • Conclusion: The maintenance of host-specific signals in spatially and temporally separated C. jejuni populations suggests the existence of strong purifying selection for this bacterium in European Blackbirds. (edu.au)
  • The isolation rate of Campylobacter spp. (who.int)
  • Campylobacter jejuni is a common raw milk contaminant and is notoriously difficult to isolate from food products, because of its fastidious growth requirements. (cdc.gov)
  • DNA extracted from C. jejuni clinical isolate Cj1 was used a positive control for amplification of primers. (cdc.gov)
  • Only one human isolate could be re-grown by the reference laboratory and was confirmed as a Campylobacter jejuni subspecies jejuni , with sensitivity to ciprofloxacin, nalidixic acid, gentamicin and tetracycline. (who.int)
  • Most cases of Campylobacter jejuni come from handling or ingesting raw or undercooked poultry meat. (medlineplus.gov)
  • This indicates adaptation, exquisite specificity, and stability in time for European Blackbirds, which is in sharp contrast with the high levels of recombination and mutation found in poultry-related C. jejuni genotypes. (edu.au)
  • Interventions to control and reduce the incidence of Campylobacter jejuni colonization in poultry is important in order to reduce the burden of foodborne illness in humans. (zootecnicainternational.com)
  • The data obtained from this study may guide the industry to develop effective vaccines to reduce C. jejuni colonization in poultry and enhance the safety of poultry products. (zootecnicainternational.com)
  • Occupational exposure to Campylobacter jejuni and autoimmune peripheral neuropathy in cattle, poultry, and swine farm ers. (cdc.gov)
  • The avian commensal bacterium Campylobacter jejuni has been reported at high prevalence in poultry and cattle, and also has been reported in swine. (cdc.gov)
  • Serum anti-C. jejuni antibodies and anti-ganglioside autoantibodies in farm ers from Iowa who work with swine, poultry, and cattle are compared to non- farm ers. (cdc.gov)
  • This is what campylobacter organisms look like through a microscope. (medlineplus.gov)
  • Quantifying bacterial evolution in the wild: A birthday problem for Campylobacter lineages by: Ben Pascoe, et al. (swan.ac.uk)
  • Biochemical characterization and identification of ferulenol and embelin as potent inhibitors of malate:quinone oxidoreductase from Campylobacter jejuni . (bvsalud.org)
  • Campylobacter jejuni - survival instincts. (bvsalud.org)
  • Conclusions: The findings provide evidence that occupational exposure to C. jejuni is an important health risk for farm ers who work with animals. (cdc.gov)
  • This study was conducted to analyse the trend of erythromycin and ofloxacin resistance among Campylobacter spp. (who.int)
  • In this study, we found the LC3 contribution to C. jejuni invasion signaling via the Rac1 signaling pathway. (tokushima-u.ac.jp)
  • Anti-infective bovine colostrum oligosaccharides: Campylobacter jejuni as a case study. (dsm.com)
  • Both the human- and canine- derived campylobacters were tested for relatedness via speciation, antibiotic susceptibility testing and pulsed-field gel electrophoresis (PFGE). (who.int)
  • In summary, puppies should not be considered as companion animals in ACFs due to high rates of Campylobacter carriage and the underlying susceptibility of the elderly. (who.int)
  • Campylobacter jejuni is one of the most common bacterial causes of diarrhea. (medlineplus.gov)
  • Earlier studies have indicated thrushes of the genus Turdus in Europe to be frequently colonized with C. jejuni , and predominately with host-associated specific genotypes. (edu.au)
  • The pathogenicity of C. jejuni is closely associated with the internalization process in host epithelial cells, which is related to a host immune response. (tokushima-u.ac.jp)
  • We performed fragment-based and high-throughput screens against an amino-sugar acetyltransferase enzyme, PglD, involved in biosynthesis of UDP-diNAcBac in Campylobacter jejuni. (figshare.com)
  • These three antigens have not been tested as vaccine candidates and have the potential to be developed into broad spectrum and effective vaccines against C. jejuni . (zootecnicainternational.com)
  • Policies to reduce exposures of farm ers and the public to C. jejuni should be considered. (cdc.gov)