Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample.
The measurement of the quantity of heat involved in various processes, such as chemical reactions, changes of state, and formations of solutions, or in the determination of the heat capacities of substances. The fundamental unit of measurement is the joule or the calorie (4.184 joules). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Calculation of the energy expenditure in the form of heat production of the whole body or individual organs based on respiratory gas exchange.
A rigorously mathematical analysis of energy relationships (heat, work, temperature, and equilibrium). It describes systems whose states are determined by thermal parameters, such as temperature, in addition to mechanical and electromagnetic parameters. (From Hawley's Condensed Chemical Dictionary, 12th ed)
The chemical reactions involved in the production and utilization of various forms of energy in cells.
Heat production, or its measurement, of an organism at the lowest level of cell chemistry in an inactive, awake, fasting state. It may be determined directly by means of a calorimeter or indirectly by calculating the heat production from an analysis of the end products of oxidation within the organism or from the amount of oxygen utilized.
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
The determination of the concentration of a given component in solution (the analyte) by addition of a liquid reagent of known strength (the titrant) until an equivalence point is reached (when the reactants are present in stoichiometric proportions). Often an indicator is added to make the equivalence point visible (e.g., a change in color).
Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein.
The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A change from planar to elliptic polarization when an initially plane-polarized light wave traverses an optically active medium. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.
A change of a substance from one form or state to another.
Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of PULMONARY SURFACTANTS.
Presence of warmth or heat or a temperature notably higher than an accustomed norm.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Layers of lipid molecules which are two molecules thick. Bilayer systems are frequently studied as models of biological membranes.
The temperature at which a substance changes from one state or conformation of matter to another.
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.
Method of using a polycrystalline powder and Rietveld refinement (LEAST SQUARES ANALYSIS) of X-RAY DIFFRACTION or NEUTRON DIFFRACTION. It circumvents the difficulties of producing single large crystals.
The rate dynamics in chemical or physical systems.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
Processes involved in the formation of TERTIARY PROTEIN STRUCTURE.
Technique whereby the weight of a sample can be followed over a period of time while its temperature is being changed (usually increased at a constant rate).
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
The characteristic three-dimensional shape of a molecule.
Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to a choline moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and choline and 2 moles of fatty acids.
The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)
The level of protein structure in which regular hydrogen-bond interactions within contiguous stretches of polypeptide chain give rise to alpha helices, beta strands (which align to form beta sheets) or other types of coils. This is the first folding level of protein conformation.
The measure of that part of the heat or energy of a system which is not available to perform work. Entropy increases in all natural (spontaneous and irreversible) processes. (From Dorland, 28th ed)
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The chemical and physical integrity of a pharmaceutical product.
Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.
Relating to the size of solids.
Artificial, single or multilaminar vesicles (made from lecithins or other lipids) that are used for the delivery of a variety of biological molecules or molecular complexes to cells, for example, drug delivery and gene transfer. They are also used to study membranes and membrane proteins.
The relative amounts of various components in the body, such as percentage of body fat.
The processes of heating and cooling that an organism uses to control its temperature.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Measurement of the intensity and quality of fluorescence.
A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)
The extent to which an enzyme retains its structural conformation or its activity when subjected to storage, isolation, and purification or various other physical or chemical manipulations, including proteolytic enzymes and heat.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to an ethanolamine moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and ethanolamine and 2 moles of fatty acids.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
NMR spectroscopy on small- to medium-size biological macromolecules. This is often used for structural investigation of proteins and nucleic acids, and often involves more than one isotope.
Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)
Elements of limited time intervals, contributing to particular results or situations.
Total number of calories taken in daily whether ingested or by parenteral routes.
Freedom from activity.
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
The physical characteristics and processes of biological systems.
The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.
Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.
The study of PHYSICAL PHENOMENA and PHYSICAL PROCESSES as applied to living things.
A nitrogen-free class of lipids present in animal and particularly plant tissues and composed of one mole of glycerol and 1 or 2 moles of phosphatidic acid. Members of this group differ from one another in the nature of the fatty acids released on hydrolysis.
Determination of the spectra of ultraviolet absorption by specific molecules in gases or liquids, for example Cl2, SO2, NO2, CS2, ozone, mercury vapor, and various unsaturated compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.
The diversion of RADIATION (thermal, electromagnetic, or nuclear) from its original path as a result of interactions or collisions with atoms, molecules, or larger particles in the atmosphere or other media. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Proteins prepared by recombinant DNA technology.
A cytosolic carbonic anhydrase isoenzyme found widely distributed in cells of almost all tissues. Deficiencies of carbonic anhydrase II produce a syndrome characterized by OSTEOPETROSIS, renal tubular acidosis (ACIDOSIS, RENAL TUBULAR) and cerebral calcification. EC 4.2.1.-
The motion of phospholipid molecules within the lipid bilayer, dependent on the classes of phospholipids present, their fatty acid composition and degree of unsaturation of the acyl chains, the cholesterol concentration, and temperature.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander.
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.
Cellular processes in biosynthesis (anabolism) and degradation (catabolism) of CARBOHYDRATES.
Lipids, predominantly phospholipids, cholesterol and small amounts of glycolipids found in membranes including cellular and intracellular membranes. These lipids may be arranged in bilayers in the membranes with integral proteins between the layers and peripheral proteins attached to the outside. Membrane lipids are required for active transport, several enzymatic activities and membrane formation.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Spectrophotometry in the infrared region, usually for the purpose of chemical analysis through measurement of absorption spectra associated with rotational and vibrational energy levels of molecules. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding.
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Particles consisting of aggregates of molecules held loosely together by secondary bonds. The surface of micelles are usually comprised of amphiphatic compounds that are oriented in a way that minimizes the energy of interaction between the micelle and its environment. Liquids that contain large numbers of suspended micelles are referred to as EMULSIONS.
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
The thermodynamic interaction between a substance and WATER.
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
The physical phenomena describing the structure and properties of atoms and molecules, and their reaction and interaction processes.
The study of CHEMICAL PHENOMENA and processes in terms of the underlying PHYSICAL PHENOMENA and processes.
Colloids with a solid continuous phase and liquid as the dispersed phase; gels may be unstable when, due to temperature or other cause, the solid phase liquefies; the resulting colloid is called a sol.
A class of sphingolipids found largely in the brain and other nervous tissue. They contain phosphocholine or phosphoethanolamine as their polar head group so therefore are the only sphingolipids classified as PHOSPHOLIPIDS.
Proteins found in any species of bacterium.
The ability of a protein to retain its structural conformation or its activity when subjected to physical or chemical manipulations.
Measurement of the polarization of fluorescent light from solutions or microscopic specimens. It is used to provide information concerning molecular size, shape, and conformation, molecular anisotropy, electronic energy transfer, molecular interaction, including dye and coenzyme binding, and the antigen-antibody reaction.
A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.
Dosage forms of a drug that act over a period of time by controlled-release processes or technology.
The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)
The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the action of cyclodextrin glucanotransferase on starch or similar substrates. The enzyme is produced by certain species of Bacillus. Cyclodextrins form inclusion complexes with a wide variety of substances.
Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.
The characteristic 3-dimensional shape and arrangement of multimeric proteins (aggregates of more than one polypeptide chain).
The glyceryl esters of a fatty acid, or of a mixture of fatty acids. They are generally odorless, colorless, and tasteless if pure, but they may be flavored according to origin. Fats are insoluble in water, soluble in most organic solvents. They occur in animal and vegetable tissue and are generally obtained by boiling or by extraction under pressure. They are important in the diet (DIETARY FATS) as a source of energy. (Grant & Hackh's Chemical Dictionary, 5th ed)
Physiological processes in biosynthesis (anabolism) and degradation (catabolism) of LIPIDS.
Established cell cultures that have the potential to propagate indefinitely.
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.
Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
Characteristics or attributes of the outer boundaries of objects, including molecules.
FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form.
Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.
A low-energy attractive force between hydrogen and another element. It plays a major role in determining the properties of water, proteins, and other compounds.
The accumulation of an electric charge on a object
A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
The process by which two molecules of the same chemical composition form a condensation product or polymer.
Nanometer-sized, hollow, spherically-shaped objects that can be utilized to encapsulate small amounts of pharmaceuticals, enzymes, or other catalysts (Glossary of Biotechnology and Nanobiotechnology, 4th ed).
Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.
Liquids transforming into solids by the removal of heat.
Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
A class of organic compounds which contain an anilino (phenylamino) group linked to a salt or ester of naphthalenesulfonic acid. They are frequently used as fluorescent dyes and sulfhydryl reagents.
Centrifugation with a centrifuge that develops centrifugal fields of more than 100,000 times gravity. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Transport proteins that carry specific substances in the blood or across cell membranes.
Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
The assembly of the QUATERNARY PROTEIN STRUCTURE of multimeric proteins (MULTIPROTEIN COMPLEXES) from their composite PROTEIN SUBUNITS.
Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.
Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.
Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)
Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.
Positively charged atoms, radicals or groups of atoms which travel to the cathode or negative pole during electrolysis.
Conformational transitions of the shape of a protein to various unfolded states.
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
The generation of heat in order to maintain body temperature. The uncoupled oxidation of fatty acids contained within brown adipose tissue and SHIVERING are examples of thermogenesis in MAMMALS.
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
Glucose in blood.
Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)
A plant genus of the family ASCLEPIADACEAE.
The exchange of OXYGEN and CARBON DIOXIDE between alveolar air and pulmonary capillary blood that occurs across the BLOOD-AIR BARRIER.
Deuterium. The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.
A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.
Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.
Computer-based representation of physical systems and phenomena such as chemical processes.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
Removal of moisture from a substance (chemical, food, tissue, etc.).
Commonly observed structural components of proteins formed by simple combinations of adjacent secondary structures. A commonly observed structure may be composed of a CONSERVED SEQUENCE which can be represented by a CONSENSUS SEQUENCE.
Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent.
The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.
Substances produced from the reaction between acids and bases; compounds consisting of a metal (positive) and nonmetal (negative) radical. (Grant & Hackh's Chemical Dictionary, 5th ed)
Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
Materials in intermediate state between solid and liquid.
That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.
A basic enzyme that is present in saliva, tears, egg white, and many animal fluids. It functions as an antibacterial agent. The enzyme catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrin. EC
An element with the atomic symbol N, atomic number 7, and atomic weight [14.00643; 14.00728]. Nitrogen exists as a diatomic gas and makes up about 78% of the earth's atmosphere by volume. It is a constituent of proteins and nucleic acids and found in all living cells.
A naphthalene derivative with carcinogenic action.
Microscopy using polarized light in which phenomena due to the preferential orientation of optical properties with respect to the vibration plane of the polarized light are made visible and correlated parameters are made measurable.
Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.
An absence of warmth or heat or a temperature notably below an accustomed norm.
The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
The deductive study of shape, quantity, and dependence. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.
The region of an enzyme that interacts with its substrate to cause the enzymatic reaction.
A genus of the family Heteromyidae which contains 22 species. Their physiology is adapted for the conservation of water, and they seldom drink water. They are found in arid or desert habitats and travel by hopping on their hind limbs.
Single membrane vesicles, generally made of PHOSPHOLIPIDS.
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.
Any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin. It is the chief storage form of energy reserve (carbohydrates) in plants.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
The amounts of various substances in food needed by an organism to sustain healthy life.

Calorimetric studies on the stability of the ribosome-inactivating protein abrin II: effects of pH and ligand binding. (1/2195)

The effects of pH and ligand binding on the stability of abrin II, a heterodimeric ribosome-inactivating protein, and its subunits have been studied using high-sensitivity differential scanning calorimetry. At pH7.2, the calorimetric scan consists of two transitions, which correspond to the B-subunit [transition temperature (Tm) 319.2K] and the A-subunit (Tm 324.6K) of abrin II, as also confirmed by studies on the isolated A-subunit. The calorimetric enthalpy of the isolated A-subunit of abrin II is similar to that of the higher-temperature transition. However, its Tm is 2.4K lower than that of the higher-temperature peak of intact abrin II. This indicates that there is some interaction between the two subunits. Abrin II displays increased stability as the pH is decreased to 4.5. Lactose increases the Tm values as well as the enthalpies of both transitions. This effect is more pronounced at pH7.2 than at pH4.5. This suggests that ligand binding stabilizes the native conformation of abrin II. Analysis of the B-subunit transition temperature as a function of lactose concentration suggests that two lactose molecules bind to one molecule of abrin II at pH7.2. The presence of two binding sites for lactose on the abrin II molecule is also indicated by isothermal titration calorimetry. Plotting DeltaHm (the molar transition enthalpy at Tm) against Tm yielded values for DeltaCp (change in excess heat capacity) of 27+/-2 kJ.mol-1.K-1 for the B-subunit and 20+/-1 kJ.mol-1.K-1 for the A-subunit. These values have been used to calculate the thermal stability of abrin II and to surmise the mechanism of its transmembrane translocation.  (+info)

Expression and characterization of the intact N-terminal domain of streptokinase. (2/2195)

Proteolytic studies have enabled two of the three putative domains of the fibrinolytic protein streptokinase to be isolated and characterized (Conejero-Lara F et al., 1996, Protein Sci 5:2583-2591). The N-terminal domain, however, could not be isolated in these experiments because of its susceptibility to proteolytic cleavage. To complete the biophysical characterization of the domain structure of streptokinase we have overexpressed, purified, and characterized the N-terminal region of the protein, residues 1-146. The results show this is cooperatively folded with secondary structure content and overall stability closely similar to those of the equivalent region in the intact protein.  (+info)

The effects of hydrostatic pressure on ribosome conformation in Escherichia coli: and in vivo study using differential scanning calorimetry. (3/2195)

Differential scanning calorimetry of whole Escherichia coil cells allowed the detection in vivo of changes in ribosome conformation. This enabled for the first time an analysis of the effects of high hydrostatic pressures on ribosomes in living cells. A correlation was observed between loss of cell viability and decrease in ribosome-associated enthalpy in cells subjected to pressures of 50-250 MPa for 20 min. Cell death and ribosome damage were therefore closely related phenomena. In pressure-treated cells, the thermogram peak temperatures decreased, suggesting that the remaining ribosomes had adopted a less stable conformation. During subsequent incubation of the cultures at 37 degrees C, peak temperatures and enthalpies gradually increased over a period of 5 h. This change in ribosome conformation had no apparent effect on cell survival, as viability continued to decrease. The addition of 5 mM MgCl2 before pressure treatment of cells prevented the reduction in stability of surviving ribosomes but had no effect on the initial loss of enthalpy or on cell viability.  (+info)

Glycosylation of asparagine-28 of recombinant staphylokinase with high-mannose-type oligosaccharides results in a protein with highly attenuated plasminogen activator activity. (4/2195)

The properties of recombinant staphylokinase (SakSTAR) expressed in Pichia pastoris cells have been determined. The single consensus N-linked oligosaccharide linkage site in SakSTAR (at Asn28 of the mature protein) was occupied in approximately 50% of the expressed protein with high-mannose-type oligosaccharides. The majority of these glycans ranged in polymerization state from Man8GlcNAc2 to Man14GlcNAc2, with the predominant species being Man10GlcNAc2 and Man11GlcNAc2. Glycosylated SakSTAR (SakSTARg) did not differ from its aglycosyl form in its aggregation state in solution, its thermal denaturation properties, its ability to form a complex with human plasmin (hPm), the amidolytic properties of the respective SakSTAR-hPm complexes, or its ability to liberate the amino-terminal decapeptide required for formation of a functional SakSTAR-hPm plasminogen activator complex. However, this latter complex with SakSTARg showed a greatly reduced ability to activate human plasminogen (hPg) as compared with the same complex with the aglycosyl form of SakSTAR. We conclude that glycosylation at Asn28 does not affect the structural properties of SakSTAR or its ability to participate in the formation of an active enzymatic complex with hPm, but it is detrimental to the ability of the SakSTAR-hPm complex to serve as a hPg activator. This is likely due to restricted access of hPg to the active site of the SakSTARg-hPm complex.  (+info)

Hydrocarbon chain packing and the effect of ethanol on the thermotropic phase behavior of mixed-chain phosphatidylglycerols. (5/2195)

Previous studies in this laboratory have delineated the relationship between the acyl chain asymmetry of mixed-chain phosphatidylcholines and the effect of ethanol concentration ([EtOH]) on their melting behavior (Li et al., Biophys J., 70 (1996) 2784-2794). This present investigation extends these findings to another phospholipid family by using high-resolution differential scanning calorimetry (DSC) to characterize the effect of ethanol concentration on the main phase transition temperature (Tm) of five molecular species of mixed-chain phosphatidylglycerol (PG). For C(14):C(18)PG, C(15):C(17)PG, C(16):C(16)PG, and C(17):C(15)PG, a biphasic profile in the Tm versus [EtOH] plot was observed, and the minimum in the plot for each PG occurred at 33, 15, 19, and 36 mg/ml, respectively. This biphasic behavior is typical of phospholipids whose acyl chain asymmetry is fairly small. For C(18):C(14)PG, only a linear decrease in the Tm was observed as a function of ethanol concentration; this effect is characteristic of highly asymmetric phospholipids. Our DSC results obtained with mixed-chain PG in the presence of ethanol demonstrate that the acyl chain asymmetry of the five lipids studied can be ranked as follows: C(15):C(17)PG+info)

Thermotropic phase behavior of mixed-chain phosphatidylglycerols: implications for acyl chain packing in fully hydrated bilayers. (6/2195)

In this communication we report the first systematic investigation of the thermodynamic properties of fully hydrated mixed-chain phosphatidylglycerols (PG) using high-resolution differential scanning calorimetry (DSC). The crystal structure of dimyristoylphosphatidylglycerol shows an acyl chain conformation that is nearly opposite to that of phosphatidylcholine (PC). In PC, the sn-1 chain is straight while the sn-2 chain contains a bend; for PG, the sn-1 contains a bend while the sn-2 chain is in the all-trans conformation (R.H. Pearson, I. Pascher, The molecular structure of lecithin dihydrate, Nature, 281 (1978) 499-501; I. Pascher, S. Sundell, K. Harlos, H. Eibl, Conformational and packing properties of membrane lipids: the crystal structure of sodium dimyristoylphosphatidylglycerol, Biochim. Biophys. Acta, 896 (1987) 77-88). If the structure of PG found in the single crystal can be extrapolated to that in the fully hydrated gel-state bilayer, the observed difference in acyl chain conformations implies that modulation of the acyl chain asymmetry will have an opposite effect on the thermotropic phase behavior of PG and PC. For example, it is expected, based on the crystal structures, that C(15):C(13)PG should have a higher main phase transition temperature (Tm) than C(14):C(14)PG, and C(13):C(15)PG should have a lower Tm than C(14):C(14)PG. However, our DSC studies show clearly that the expectation is not borne out by experimental data. Rather, the Tm values of C(15):C(13)PG, C(14):C(14)PG, and C(13):C(15)PG are 18.2 degrees C, 23.1 degrees C, and 24.4 degrees C, respectively. Several other PGs, each with a unique acyl chain composition, have also been studied in this laboratory using high-resolution DSC. It is shown that the acyl chain conformation of fully hydrated PG in general is nearly opposite to that seen in the PG crystal structure.  (+info)

An ordered metastable phase in hydrated phosphatidylethanolamine: the Y-transition. (7/2195)

By using time-resolved X-ray diffraction, differential scanning calorimetry and scanning densitometry, we observed rapid formation at low temperature of a metastable ordered phase, termed LR1 phase, in fully hydrated dihexadecylphosphatidylethanolamine (DHPE). The LR1 phase has the same lamellar repeat period as the gel Lbeta phase but differs from the latter in its more ordered, orthorhombic hydrocarbon chain arrangement. It forms at about 12 degrees C upon cooling and manifests itself as splitting of the sharp, symmetric wide-angle X-ray peak of the DHPE gel phase into two reflections. This transition, designated the 'Y-transition', is readily reversible and proceeds with almost no hysteresis between cooling and heating scans. Calorimetrically, the LR1-->Lbeta transition is recorded as a low-enthalpy (0.2 kcal/mol) endothermic event. The formation of the LR1 phase from the gel phase is associated with a small, about 2 microl/g, decrease of the lipid partial specific volume recorded by scanning densitometry, in agreement with a volume calculation based on the X-ray data. The formation of the equilibrium Lc phase was found to take place from within the LR1 phase. This appears to be the only observable pathway for crystallisation of DHPE upon low-temperature incubation. Once formed, the Lc phase of this lipid converts directly into Lbeta phase at 50 degrees C, skipping the LR1 phase. Thus, the LR1 phase of DHPE can only be entered by cooling of the gel Lbeta phase. The data disclose certain similarities between the low-temperature polymorphism of DHPE and that of long-chain normal alkanes.  (+info)

Thermodynamics of the reconstitution of tuna cytochrome c from two peptide fragments. (8/2195)

Two peptide fragments from tuna cytochrome c (cyt c), N-fragment (residues 1-44 containing the heme) and C-fragment (residues 45-103), combine to form a 1:1 fragment complex. This was clearly proved by ion-spray mass spectrometry. It was found from CD and NMR spectra that the structure of the fragment complex formed is similar to that of an intact cyt c, although each isolated fragment itself is unstructured. Binding constants and enthalpies upon the complex formation were directly observed by isothermal titration calorimetry. Thermodynamic parameters (deltaG(o)b, deltaHb, deltaS(o)b, and deltaC(b)p)) associated with the complex formation were determined at various pHs and temperatures. DeltaHb was found to be almost independent of pH values. The change in heat capacity accompanying the complex formation (deltaC(b)p) was directly determined from the temperature dependence of deltaHb. In addition, the change in heat capacity and enthalpy upon tuna cyt c unfolding were determined by differential scanning calorimetry. Thermodynamic parameters for the unfolding/dissociation process of the fragment complex were compared with those for cyt c unfolding at pH 3.9 and 303 K. In a comparison of two unfolding processes, the heat capacity change of each was very close to the other, while both the unfolding enthalpy and entropy of the fragment complex were larger than those of tuna cyt c. These thermodynamic data suggest that the internal interactions between polar groups (hydrogen bonding) and nonpolar groups (van der Waals interactions) are preserved in the fragment complex as well as in the native state of cyt c.  (+info)

We investigated the thermotropic phase behavior of the distearoylphosphatidylcholine (DSPC)-cholesterol binary bilayer membrane as a function of the cholesterol composition (X(ch)) by fluorescence spectroscopy using 6-propionyl-2-(dimethylamino)naphthalene (Prodan) and differential scanning calorimetry (DSC). The fluorescence spectra, each of which has a single maximum, showed that the wavelength at the maximum intensity (lambda(max)) changed depending on the bilayer state: ca. 440 nm for the lamellar gel (L(beta) or L(beta)) and the liquid ordered (L(o)) phases, ca. 470 nm for the ripple gel (P(beta)) phase and ca. 490 nm for the liquid crystalline (L(alpha)) phase, respectively. The transition temperatures were determined from the temperature dependences of the lambda(max) and endothermic peaks of the DSC thermograms. Both measurements showed that the pretransition disappears around X(ch)=0.035. The constructed temperature-X(ch) phase diagram indicated that the phase behavior of the binary ...
Abstract:. Several techniques were compared for improving the dissolution of indomethacin (IND), a poorly soluble non-steroidal anti-inflammatory drug. The aim of this study was to prepare, characterize and differentiate the different techniques used as physical mixture (PM), jet milling (JM) and solid dispersion (SD). The PM, JM, and SD techniques were prepared at 1:4 drug to polymer ratio with both polyethylene glycol (PEG) 6000 and 10000. Scanning electron microscope (SEM), X-ray powder diffractometry (X-ray) and differential scanning calorimetry (DSC) were used to examine the physical state of the drug. Furthermore, the solubility and the dissolution rate of the drug in its different systems were explored. The data from the X-ray showed that the crystallinity of the drug was still detectable (slightly disappeared) in its solid state in the physical mixture, jet milling of IND-PEG, whereas it disappeared in SD of IND-PEG. DSC thermograms showed the significant change in melting peak of the ...
Wet milling by a multi-ring media mill was carried out for aqueous slurries of Mg(OH)2 and TiO2 powder mixtures in the concentration range from 6.9 to 50 wt%. Rings used as grinding media were made of partially stabilized zirconia or polyoxymethylene. Products were characterized by thermogravimetry-differential thermal analysis, X-ray diffractometry and EPMA. ZrO2 contamination in the product was determined by X-ray flurescence analysis. The temperature of endothermic peaks of dehydration remained almost unchanged regardless of slurry concentration but decreased with increasing compressive force exerted by grinding rings. The homogeneity of the product is correlated with the temperature of exothermic peaks above 1100 K due to the crystallization of MgTiO3, but not with the endothermic peaks around 650 K. The increase of the slurry concentration increases the homogeneity of the product, facilitating the formation of single-phase MgTiO3 on subsequent heating. The increase of the compressive force of
31 P-NMR and Differential Scanning Calorimetry Studies for Determining Vesicleâ s Drug Physical State and Fraction in Alendronate Liposomes Abstract.
Sodium chloride, the same substance that you sprinkle on your french fries for lunch, is a useful chemical. One of its most useful qualities is heat absorption. Salt -- the more common name for sodium chloride -- is a crystal that can absorb heat very effectively because of its particular physical and chemical ...
The objective of this science fair project is to observe the differences in heat absorption for darker colors vs. lighter colors.
Reversible transition of the ZP meshwork status by substitution treatment with dcp11 and gpp2.(a) RCAI staining of the VE substitutionally treated with dcp11 an
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Differential Scanning Calorimetry (DSC) data is used to advance stable and developable proteins into the pipeline, while optimising process and formulation conditions to maintain stability between manufacture and storage.. In 2017, Malvern launched the new MicroCal PEAQ-DSC Automated System, which has new features such as PEAQ-compliance, performance increases, smart experimental design and analysis software, and an autosampler.. This free whitepaper discusses eight reasons why you should update your MicroCal VP-Capillary DSC to the new system, including topics such as DSC data analysis in the regulated environment, increasing DSC productivity, experimental sample and scan set-up, automated objective data analysis, and objective study of data for compareability and biosimilarity studies.. ...
You may also wish to search for items by Faradjzadeh. 15 matching references were found. Wilhelm, E.; Faradjzadeh, A.; Grolier, J.-P.E., Molar excess heat capacities and excess volumes of 1,2-dichloroethane + cyclooctane, + mesitylene, and + tetrachloromethane, J. Chem. Thermodynam., 1979, 11, 979-984. [all data] Wilhelm, E.; Faradjzadeh, A.; Grolier, J.-P.E., Excess volumes and excess heat capacities of 2,3-dimethylbutane + butane and + toluene, J. Chem. Thermodynam., 1982, 14, 1199-1200. [all data] Wilhelm, E.; Faradjzadeh, A.; Grolier, J.-P.E., Excess volumes and excess heat capacities of 2,3-dimethylbutane + benzene and + toluene, J. Chem. Thermodyn., 1982, 14, 1199-200. [all data] Guieu, R.; Faradjzadeh, A.; Carbonnel, L., Int. DATA Ser., Sel. Data Mixtures, Ser. A, 1980, No. 1, 57. [all data] Guieu, R.; Faradjzadeh, A.; Carbonnel, L., Int. DATA Ser., Sel. Data Mixtures, Ser. A, 1980, No. 1, 58. [all data] Guieu, R.; Faradjzadeh, A.; Carbonnel, L., Int. DATA Ser., Sel. Data Mixtures, Ser. ...
Figure 3 confirms the existence of a disordered structure both below and above the transition temperature as detected by the DSC experiment. The temperature evolution of the structure of the liquid has been followed looking at the Q position of the first maximum (around Q=13 nm-1) and minimum (around Q=4 nm-1) of I(Q) respectively identified as positions QA and QB.The Q values of these two points, reported as a function of temperature in the insets of Figure 3, show a jump at the temperatures corresponding to the LTL-HTL transition, as derived by the DSC measurements. The three transition temperatures for the maxima (full triangle) and the minima (full stars) of I(Q) reported on the phase diagram of Figure 2 show good agreement.. The combination of DSC and X-ray diffraction allowed us to draw the phase diagram of a solution undergoing inverse melting and to characterise the two different microscopic local structures of the disordered fluid phases, the LTL and the HTL observed in the low ...
This thesis describes the work done with various liptins on lipid membranes. The liptins are organic molecules designed to interact with bacteria in hopes of reducing the antimicrobial resistance threat. The hypothesis is that the liptins will have a pocket which can interact with phosphatidylglycerol, PG, on the phospholipid membrane. With this interaction, the liptins binds to the membrane and causes membrane destabilization. Various lipids vesicles were prepared and liptins were introduced to examine the effect. By the use of differential scanning calorimetry (DSC), and fluorescence efflux studies, details about the liptin interactions can be investigated. The DSC studies reveal that the liptins affect the membrane bilayer by reducing the enthalpy of the transition from gel ordered phase to liquid disordered phase, while keeping the transition temperature constant. As for the fluorescence efflux studies, they reveal information on possible pore formation induced in the membrane by the liptins ...
Theory Seminar: Probing Gravitational Waves from First-Order Phase Transitions at eLISA Monday, 29 February 2016 from 12:00 to 13:00 (Europe/...
Using differential scanning calorimetry (DSC) and plate count (PC), growth of Escherichia coli was measured in four initial E. coli cell concentrations cultured in tryptic soy broth (TSB) at 35C. The calorimeter measured the energy released and/or absorbed by E. coli cells during growth and expressed it as thermograms. The resulting thermograms accurately reflected cell growth and activity, and exhibited a close correlation with growth values recorded by PC. Heat release decreased notably in the final stage of the logarithmic growth phase, and no signal was generated once the stationary phase had begun. DSC accurately quantified growth in E. coli at different initial cell concentrations grown in TSB at 35C. Depending on initial E. coli concentration, DSC detected growth starting after just a few minutes and up to five hours. The detection limit of calorimeter was 4.3 0.4 log10 CFU. DSC is an effective alternative method for measuring bacterial growth in TSB in real time. This is the first report ...
PAPER Polar phase transitions in heteroepitaxial stabilized La0.5Y0.5AlO3 thin films Shenghua Liu1, Chunfeng Zhang1, Mengya Zhu1, Qian He2, Jak Chakhalian3, Xiaoran Liu3,4, Albina Borisevich2, Xiaoyong Wang1 and Min Xiao1,4 Published 1 September 2017 • © 2017 IOP Publishing Ltd Journal of Physics: Condensed Matter, Volume 29, Number 40 Article PDF Figures References PDF 18 Total downloads Turn on MathJax Get permission to re-use this article Share this article Article information Abstract We report on the fabrication of epitaxial La0.5Y0.5AlO3 ultrathin films on (001) LaAlO3 substrates. Structural characterizations by scanning transmission electron microscopy and x-ray diffraction confirm the high quality of the film with a − b + c − AlO6 octahedral tilt pattern. Unlike either of the nonpolar parent compound, LaAlO3 and YAlO3, second harmonic generation measurements on the thin films suggest a nonpolar-polar phase transition at T c near 500 K, and a polar-polar phase transition at T a ...
Author: Riske, Karin A. et al.; Genre: Journal Article; Published in Print: 2003; Title: DMPG gel-fluid thermal transition monitored by a phospholipid spin labeled at the acyl chain end
Present work study the effect of high-pressure crystallization on morphology and thermal behavior of two different homopolymers of isotactic poly(1-butene). Both materials were non-isothermally crystallized under pressure in range from 20 to 200 MPa using a pvT100 apparatus and thus prepared samples were investigated using wide-angle X-Ray scattering, differential scanning calorimetry and polarized light microscopy. Results showed significant effect of pressure on formation of metastable phases I and II with respect to material properties on thermal behavior and morphology in isotactic poly(1-butene ...
Abstract: Topological strings on Calabi--Yau manifolds are known to undergo phase transitions at small distances. We study this issue in the case of perturbative topological strings on local Calabi--Yau threefolds given by a bundle over a two-sphere. This theory can be regarded as a q--deformation of Hurwitz theory, and it has a conjectural nonperturbative description in terms of q--deformed 2d Yang--Mills theory. We solve the planar model and find a phase transition at small radius in the universality class of 2d gravity. We give strong evidence that there is a double--scaled theory at the critical point whose all genus free energy is governed by the Painlevé I equation. We compare the critical behavior of the perturbative theory to the critical behavior of its nonperturbative description, which belongs to the universality class of 2d supergravity. We also give evidence for a new open/closed duality relating these Calabi--Yau backgrounds to open strings with framing ...
Differential scanning calorimetric thermograms of oxatomide (1), β-cyclodextrin (2), physical mixture (3), kneaded mixture (4), coevaporated (5), freeze-dried
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A number of compositions of ceramic oxide high T(sub c) superconductors were elevated for their glass formation ability by means of rapid thermal analysis during quenching, optical, and electron microscopy of the quenched samples, and with subsequent DSC measurements. Correlations between experimental measurements and the methodical composition changes identified the formulations of superconductors that can easily form glass. The superconducting material was first formed as a glass; then, with subsequent devitrification, it was formed into a bulk crystalline superconductor by a series of processing methods.. ...
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When gases evolve during a chemical reaction, a fraction of the reaction heat is lost with them. We have analyzed, both theoretically and experimentally, the deviations that this effect can produce on the determination of the reaction heat by differential scanning calorimetry (DSC). It is shown that, even in the absence of gas overheating, deviations related to variations in the sample heat capacity can be substantial in experiments involving very intense DSC peaks. However, experiments performed on thermal decomposition of metal organic salts and on evaporation of liquids have shown that deviations usually arise from gas ...
Endotherm Life Science Molecules bietet als Auftragsforschungsunternehmen hochwertige Substanzen zur Entwicklung neuer Arzneistoffe für die Medizinische Chemie, und Biomarker für die Entwicklung von diagnostischen Testverfahren an.Die Produktpalette umfasst u.a. fokussierte und diversifizierte Substanzbibliotheken, Referenzstandards, Synthesebausteine, Pharmawirkstoffe und deren Verunreinigungen, Fluoreszenzfarbstoffe sowie Naturstoffe und ihre Metabolite.
Endotherm Life Science Molecules bietet als Auftragsforschungsunternehmen hochwertige Substanzen zur Entwicklung neuer Arzneistoffe für die Medizinische Chemie, und Biomarker für die Entwicklung von diagnostischen Testverfahren an.Die Produktpalette umfasst u.a. fokussierte und diversifizierte Substanzbibliotheken, Referenzstandards, Synthesebausteine, Pharmawirkstoffe und deren Verunreinigungen, Fluoreszenzfarbstoffe sowie Naturstoffe und ihre Metabolite.
Flash Differential Scanning Calorimetry revolutionizes rapid-scanning DSC. The Flash DSC 1 can analyze reorganization processes that were previously impossible to measure.
A method and apparatus for simultaneous differential scanning calorimetry and microdielectrometry is disclosed. The apparatus includes a sample cell containing a sensor for measuring the dielectric and thermal properties of the sample. The method applies a voltage to a material while heating the material over a temperature range and then simultaneously measuring the current gain of the material, the temperature of the material and the energy input to the material.
The catalytic effects of MnFe2O4 nanoparticles on the dehydrogenation properties of NaAlH4, prepared by ball milling, are investigated. The onset temperatures for NaAlH4 + 7 mol% MnFe2O4 are 95 C, 152 C and 327 C for the ...
Contact ePrints Soton: [email protected] ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2. This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.. ...
A dense article that includes a dense TFE copolymer film is provided. The dense TFE copolymer film includes a first endotherm between about 50 C. and about 300 C., a second endotherm between about 320 C. and about 350 C., and a third endotherm between about 350 C. and about 400 C. To form the dense article, a core shell TFE copolymer is formed into a pellet, ram extruded into a tape, dried into a dried preform, and then stretched into a dense TFE copolymer film that exhibits improved physical and mechanical properties. The dense TFE copolymer film is produced directly from the dried preform at a deformation temperature less than about 335 C. and without increasing the porosity of the dried preform, as would conventionally be done in expansion processes. The dense TFE copolymer films have a methane permeability less than about 20 μg*micron/cm2/min. The dense articles have a void volume less than about 20%.
Metal roofs are excellent materials that have excellent durability and exceptoinal performance. However, how can you reduce their heat absorption?
Polymer chain motion was not restricted by the ORMOGLASS and two different phases were present in contrast to what was previously observed in ormoglass coated PLA.17 Differential scanning calorimetry (DSC) results showed that the thermal properties of the polymer were globally not affected by the incorporation of the ORMOGLASS. In fact, the thermograms of the hybrid fibers associated with the first heating ramp were similar to those of PLA fibers. Moreover, based on the second heating ramps, no significant differences in Tg were observed for the PLA and the hybrid fibers, as expected (Fig. S4, ESI†). Interactions at the nanometric level can be created thanks to the intrinsic advantages of the fabrication method,24 but no strong chemical interactions, able to induce significant modifications in Tg, were formed. Note that Tg in this amorphous PLDLLA (70% LL/30% LD PLA) ranges between 55 and 60 °C and basically depends on the molecular weight.25 The higher the ORMOGLASS content, the earlier the ...
By Darcy Simonis, ABB Food and beverage production requires a large range of temperatures. This means that plants must have effective cooling systems to deal with the excess heat. Removing the excess heat from the system requires a cooling tower, however, traditional designs require frequent maintenance
where ki is the degree of node i, α and a are tunable parameters. In spatial driven model (a = 0), the spatial distance distribution follows the power-law feature. The mean topological distance l and the clustering coefficient C exhibit phase transitions at same critical values of α which change with the dimensionality d of the embedding space. When a ≤ 0, the degree distribution follows the shifted power law (SPL) which interpolates between exponential and scale-free distributions depending on the value of a. ...
Our DSC portfolio of applications, instruments and services, combined with our expertise in materials characterization, can help you push the edge of science. Greater access to insights, a far more effective work experience and the answers you need.
By simulating from a half-gel starting structure, we are able to determine accurately the phase transition temperature of pentadecanes with the optimized L-OPLS parameters (Siu et al., JCTC 2012 ...
Studies on a complete range of reservoir types to support the engineering, design and optimization of reservoirs, processes and facilities.
DSC是聚合物分析的一大利器,像熔点,结晶温度,玻璃化转变温度等聚合物的关键特性都可以由DSC测得。但是,想要用好这个利器并不那么简单。本次讲座就向大家介绍DSC测试的秘籍,告诉大家如何进行从测试到分析到解谱的聚合物DSC一条龙分析。在你面对样品无所适从时,如何用SmartMode帮你设计测试方案;在你面对结果无从下手时,如何用AutoEvaluation帮你进行分析;在你面对图谱一脸迷茫的时候,如何用Identify帮你辨别样品。这些内容,你都可以从这次讲座里学到 ...
TY - JOUR. T1 - Structural Phase Transitions at Clean and Metal-Covered Si(111) Surfaces Investigated by Rheed Spot Analysis. AU - Hasegawa, Shuji. AU - Nagai, Yasuyoshi. AU - Oonishi, Toshio. AU - Kobayashi, Nobuhiko. AU - Miyake, Takashi. AU - Murakami, Shuuichi. AU - Ishii, Yuuji. AU - Hanawa, Daiki. AU - Ino, Shozo. PY - 1995/3/1. Y1 - 1995/3/1. N2 - Structural phase transitions between various kinds of superlattice structures formed on a Si(111) surface have been investigated by spot analysis of reflection high-energy electron diffraction (RHEED). Reversible transitions induced by temperature changes and irreversible ones induced by metal depositions were observed. Detailed discussions on the dynamics of the phase transitions are made by quantitative analyses of integrated spot intensity and profile. For a phase transition of 7x7âŸ1x1 structures on a clean Si(111) surface, a hysteresis with temperature difference of 5° C between in heating and cooling processes was found in the spot ...
Paracetamol is a sparingly soluble bitter tasting drug. It is widely used as an analgesic and antipyretic. Complexation of drug with different cyclodextrins (?, ? and HP-?-CD) was attempted to improve solubility of Paracetamol. During the drug excipient interaction studies, ?, ? cyclodextrins elicited analytical interference and showed considerable absorbance at ?max (243.5 nm) of Paracetamol while the ones constituting of hydroxypropyl-beta-cyclodextrin (HP-?-CD) did not show any such interference. Therefore, the present study is concentrated on exploring HP-?-CD as complexing agent. Phase solubility studies showed that complexation of Paracetamol/HP-?-CD at molar ratio 1:1 and showed AL type solubility curve. Complexation was done by various methods like physical mixing, kneading and freeze drying and resulting drug complexes were characterized by Differential Scanning Calorimetry (DSC) and Fourier Transform Infrared Spectroscopy (FTIR). The thermograms obtained showed an endothermic peak for
A preliminary thermo gravimetric measurement was performed over a temperature range from room temperature to 240 °C. Beginning at room temperature the mass loss rate increased steadily, reaching a maximum at 94°C and exhibiting a small shoulder in the DTG curve at 107°C,. Mass loss was complete at 115°C, taking into account the initial mass loss from purging (21.7%) before the start of the measurement. There was no residue left. The DSC measurements were performed twice. To determine a possible boiling point more precisely a crucible lid with a hole of 50 Om diameter was used in the measurements. The small hole causes the generation of a defined atmosphere at constant pressure inside the crucible and allows measurements at near equilibrium conditions, thus preventing evaporation of the test material before reaching the boiling point. The sample was quenched down to -150°C. Upon heating the enthalpy curves show a small exothermic peak at -135°C (crystallisation) and a small endothermic peak ...
During the heating phase an endothermic effect was observed in the temperature range of 50 - 70 °C, which can be assigned to the melting of the test item. The test item showed a second endothermic signal in the temperature range of approx. 160 - 270 °C that can be assigned to the boiling of the test item. For the correction of the boiling temperature to standard pressure the test item was assigned to chemical group 2 (e.g. Hydrocarbons). A correction value φ = 5.05 was used for the temperature of 240 - 250 °C. The lowest measured onset temperature is corrected to the standard pressure to be 243.23 °C and the highest onset temperature to be 243.53 °C. As the corrected onset temperatures in both tests deviate less than 0.5 K from their mean value of 243.38 °C, the test item has a boiling point of 243.4 °C. No further thermal effects were observed up to the maximum test temperature of 500 °C. Final Results The test item has a boiling point of 243.4 °C corrected to normal atmospheric ...
They carried out DSC studies on the cyclopropane and on the bromodiene. The first step involves dibromocarbene addition to the but-2-ene and noted that the cyclopropane decomposes at an onset temperature of 145°C releasing 360 J/g and the diene at 226°C delivering 500 J/g. Both non-trivial amounts of energy. According to their SOPs a 100°C difference between onset temperature and reaction temperature must be observed for a decent safety margin to be maintained. To get around this problem two thing were done a) the dibromocyclopropane was isolated and b) the conversion to the bromodiene was carried out in a continuous flow reactor. A further complication is that the dibromocyclopropane is sensitive to basic conditions and careful work-up conditions had to be chosen to avoid high pH. Using t-BuOK/CHBr3 in heptanes the reaction was addition controlled at 0°C and gave a 98% yield of the diene precursor.. It was determined that the bromodiene was optimally synthesised by using a reaction ...
TY - JOUR AU - Balanč, Bojana AU - Ota, Ajda AU - Đorđević, Verica AU - Sentjurc, Marjeta AU - Nedović, Viktor AU - Bugarski, Branko AU - Poklar-Ulrih, Nataša PY - 2015 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3075 AB - The influence of resveratrol encapsulated into liposomes (prepared with a commercial lipid mixture of phospholipids, phospolipon 90NG, using the thin film and proliposome methods) on the structural properties of the liposome membrane was investigated by electron paramagnetic resonance (EPR) spectroscopy, fluorescence spectroscopy, and differential scanning calorimetry. Two fluorophores and two spin probes were used to monitor the characteristics of membranes made from a commercial mixture of phosphatidylcholine. Resveratrol was positioned rather in the inner part of the liposome membranes causing reduction in membrane fluidity. Moreover, resveratrol induced a concentration-dependent decrease in the gel-to-liquid crystalline phase transition temperature (from 41.3 ...
Abstract: We use holographic techniques to study SU(Nc) super Yang-Mills theory coupled to Nf ,, Nc flavours of fundamental matter at finite temperature and baryon density. We focus on four dimensions, for which the dual description consists of Nf D7-branes in the background of Nc black D3-branes, but our results apply in other dimensions as well. A non-zero chemical potential mu or baryon number density n is introduced via a nonvanishing worldvolume gauge field on the D7-branes. Ref. [1] identified a first order phase transition at zero density associated with `melting of the mesons. This extends to a line of phase transitions for small n, which terminates at a critical point at finite n. Investigation of the D7-branes thermodynamics reveals that (d mu / dn)_T ,0 in a small region of the phase diagram, indicating an instability. We comment on a possible new phase which may appear in this region ...
Polyester-like thermoplastic products obtained as a result of the reaction between lignins and terephthaloyl chrolide were examined. Steam exploded lignin (L) and sodium lignosulphonates (LS) were modified with terephthaloyl chloride. Some molecular and thermal properties of lignin modificates were determined. As a result of TG analysis it can be stated that modified product have higher temperature of a maximum weight loss than initial lignins. In thermograms of the initial lignins only endothermic peaks at 124 and 121°C for LS and 111°C for L can be observed. In case of modified LS the additional enothermic peak at 401°C is noticed. It is probably caused by thermal decomposition of the products. For modified product of LS an exothermic peaks at 313°C is observed. Molecular properties of lignins and products of their modification were evaluated using gel permeation chromatography (GPC). Due to GPC application a comparison of molecular weight distribution both for lignins and for products of ...
Polyester-like thermoplastic products obtained as a result of the reaction between lignins and terephthaloyl chrolide were examined. Steam exploded lignin (L) and sodium lignosulphonates (LS) were modified with terephthaloyl chloride. Some molecular and thermal properties of lignin modificates were determined. As a result of TG analysis it can be stated that modified product have higher temperature of a maximum weight loss than initial lignins. In thermograms of the initial lignins only endothermic peaks at 124 and 121°C for LS and 111°C for L can be observed. In case of modified LS the additional enothermic peak at 401°C is noticed. It is probably caused by thermal decomposition of the products. For modified product of LS an exothermic peaks at 313°C is observed. Molecular properties of lignins and products of their modification were evaluated using gel permeation chromatography (GPC). Due to GPC application a comparison of molecular weight distribution both for lignins and for products of ...
High sensitivity differential scanning calorimetry (d.s.c.) and uv-visible spectrophotometry have been used to study the thermal unfolding of alpha-chymotrypsin in presence of calcium chloride at pH = 2.8, 3.4, 5.0, 7.0, and 8.2. Quantitative thermodynamic parameters accompanying the thermal transitions have been evaluated. In the absence of calcium ions, the thermal denaturation of a-chymotrypsin is a reversible process giving a ratio of the vant Hoff to calorimetric enthalpy of 0.92 at pH = 2.8. At pH values higher than 5.0, the thermal denaturations in the absence of calcium chloride were observed to be completely irreversible. In the presence of calcium chloride, alpha-chymotrypsin undergoes irreversible thermal denaturation and its thermal transitions are found to be scan-rate dependent fitting to the model N-2 --, I, yielding an average activation energy of (419 +/- 16) kJ (.) mol(-1) using different approaches at pH = 2.8. It is also observed that at pH 2.8 and 3.4, calcium reduces the ...
However, above 50 K the thermal expansivity of the cell volume for the heating sequence is markedly lower when compared with the cooling sequence. Similar behaviour is shown by the a, c and b lattice constants, whereas the b lattice constant exhibits a less negative expansion. The thermal treatment of the sample offers a likely explanation for this observation. The sample was initially quenched at 100 K and then cooled to 5 K. Data recorded on warming this sample were composed entirely of the phase II structure until the transition onset around 210 K. In contrast, the phase II sample for the cooling sequence was transformed via the phase I structure and lattice parameters for both phases could be refined down to 167 K. Very weak peaks corresponding to the phase I structure were in fact observed down to 100 K. The intergrowth of phase II and phase I structures and sluggish nature of the transition would both affect the observed thermal expansivity of phase II in the cooling sequence. ...
For this endpoint one study is available. The explosive properties of the test item were assessed according to Regulation EC No. 440/2008 Method A.14. Explosive Properties and OECD Test Guideline 113 (1981): Thermal Stability (DSC measurement). In the DSC-measurement the energy of the exothermic decomposition of the test item was , -500 J/g. The onset temperature for the exothermic decomposition was 350°C. Therefore, further tests for explosive properties had not to be performed. It is concluded that the test item has no explosive properties. ...
This article reports the temperature dependence of the structural and photoelectrical properties of C60 thin films with varying crystal structure and oxygen content near the orientational disorder/order phase transition at about 260 K. X-ray diffraction data demonstrate that highly crystalline oxygen-free C60 films undergo the first-order phase transition at 252 K with a lattice parameter discontinuity Δa/a of 0.22%; no discontinuity was observed in C60 films with coexisting amorphous and nanocrystalline phases. A strong effect of the phase transition on the dark- and photoconductivity in those films is presented: In highly crystalline C60 films both dark- and photoconductivity increase as the temperature is lowered through the transition region. However, opposite temperature changes of the conductivity are observed in nanocrystalline/amorphous C60 films. In situ exposure of samples to oxygen gas suppresses any critical behavior. The experimental results are interpreted in terms of ...
Polymorphic transitions of α-phenylcinnamic acid stereoisomers crystallized from various solvents (CHCl3, ethanol, diethyl ether), precipitated with different acids (acetic acid or HCl) or sublimed have been studied by differential scanning calorimetry (DSC). Measurements were also supplemented by powder X-ray diffractometry (XRD). Polymorphic transitions were not found for any of the E isomer samples irrespective of the method of treatment. However, in heating-cooling cycles reversible transitions could be detected for the Z isomer. On heating an exothermic peak was registered on samples sublimed, crystallized from ethanol or diethyl ether before melting, while samples precipitated by HCl or crystallized from chloroform exhibited more complex transitions. Here, endothermic effects were also observed. Enthalpy values for transformations (either for melting or polymorphic and other transitions) are also given. ...
Most polymeric materials are based on non-renewable fossil resources, respectively petrochemicals. As regenerable resources carbohydrates have attracted great attention in the last decade for production of polymeric materials. The biodegradable polymers are indispensable in the modern society and their importance is continuously growing. In this paper we report the thermal properties of a new class of biodegradable copolymers derived from monosaccharides. The glycomonomers 3-O-acryloyl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose, and 1-O-acryloyl-2,3:5,6-di-O-isopropylidene-α-D-mannofuranose, were co-polymerized with 2-hydroxypropyl methacrylate, using benzoyl and lauroyl peroxide as initiators. The copolymerization process between glycomonomers and 2-hydroxypropyl methacrylate was studied using differential scanning calorimetry analysis (DSC). The storage and loss modulus were evaluated using DMA technigue (dynamic mechanical analysis), while the thermal stability of the obtained products ...
TY - JOUR. T1 - Fabrication and characterization of a solid polymeric electrolyte of PAN-TiO2-LiClO4 AU - Abd Rahman, Mohd Yusri. AU - Ahmad, Azizan. AU - Ismail, L. H C. AU - Mat Salleh, Muhamad. PY - 2010/2/15. Y1 - 2010/2/15. N2 - The ionic conductivity of PAN-TiO2-LiClO4 as a function of TiO2 concentration and temperature has been reported. The electrolyte samples were prepared by solution casting technique. Their conductivity was measured using the impedance spectroscopy technique. The highest room temperature conductivity of 1.8 × 10-4 S cm-1 was obtained at 7.5 wt % of TiO2 filler. It was observed that the relationship between temperature and conductivity were linear, fitting well in Arrhenius and not in Vogel-Tamman-Fulcher equation. The pre-exponential factor, σ0 and Ea are 1.8 × 10-4 S cm-1 and 0.15 eV, respectively. The conductivity data have been supported by differential scanning calorimeter (DSC) analysis. DSC analysis showed that there was a significant change in glass ...
Dortmund Data bank - Thermophysical Properties | Benzene, CAS Number: 71-43-2 | 1-Propanol, CAS Number: 71-23-8 | SpringerMaterials 2014
An endotherm (from Greek ἔνδον endon within and θέρμη thermē heat) is an organism that maintains its body at a metabolically favorable temperature, largely by the use of heat set free by its internal bodily functions instead of relying almost purely on ambient heat. Such internally generated heat is mainly an incidental product of the animals routine metabolism, but under conditions of excessive cold or low activity an endotherm might apply special mechanisms adapted specifically to heat production. Examples include special-function muscular exertion such as shivering, and uncoupled oxidative metabolism such as within brown adipose tissue. Only birds and mammals are extant universally endothermic groups of animals. Certain lamnid sharks, tuna and billfishes are also endothermic. In common parlance, endotherms are characterized as warm-blooded. The opposite of endothermy is ectothermy, although in general, there is no absolute or clear separation between the nature of ...
A paper structure having at least three regions is disclosed. The paper structure has a first region, a patterned second region, and a third transition region connecting the first and second regions. The first and second regions are disposed at different elevations, and can each have a thickness less than a thickness of the transition region. An apparatus and process for making such a paper structure are also disclosed.
This is also reflected in the solubility versus temperature phase diagram (Fig. 3A), which shows a region of concentrations where the HB oligomer is unstable (below the dashed purple line and above the black solubility line) and a region where the oligomer is metastable (above the dashed purple line). Similar arguments can be made for the other metastable phases, such as the two, three, and four β-sheet fibril phases. We emphasize that we did not calculate free energies as we were able to calculate the solubilities directly; the discussion here is mainly presented for pedagogical purposes.. Knowledge of the thermodynamically stable and metastable phases in the phase diagram allows us to determine the conditions under which the oligomer or fibril can form. A previous discontinuous molecular dynamics (DMD) study of Aβ16-22 kinetic aggregation by Cheon et al. (6) found that at 20 mM and T* = 0.2, corresponding to 342 K, a system of peptides in a random configuration first forms a fibril nucleus, ...
FT-IR and 2D correlation spectroscopy were employed to study the microstructural changes ocurring during phase transitions of a liquid crystal poly(amidoamine) codendrimer (PAMAM (L1)16(L2)16) generation 3, functionalized on the terminal groups by one-chain promesogenic calamitic units (4-(4-decyloxybenzoyloxy)salicylaldehyde (L1)) and two-chain promesogenic calamitic units (4-(3,4-didecyloxybenzoyloxy)salicylaldehyde (L2)). Spectral modifications associated with molecular conformation rearangements allowing for molecular shape change on going from a liquid−crystalline organization to another were found. The transition temperatures were calculated, and they are in good agreement with the DSC data. Spectral analysis gives evidence of the LC phase transitions and to an additional transition associated with the existence of conformers. Various types of hydrogen bonding have been established ...
When an object absorbs light, the light energy is transferred to heat energy. The amount of heat that is absorbed depends on whether the color of the object reflects, absorbs or transmits. Simple science experiments are possible to determine how different colors respond to light and how much heat each color absorbs.
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Thermogram of a cat. The different colours represent different temperatures. The lightest colours are the hottest temperatures, while the darker colours represent cooler temperatures. Thermography uses special cameras that can detect light in the far-infrared range of the electromagnetic spectrum (900-14,000 nanometers or 0.9-14 µm) to create an image that represents an objects temperature. - Stock Image Z934/0730
Industrially textured PLA multifilaments were heat set under different conditions at 110 ºC for 1 min and subjected to one cycle of deformation up to 20%. Thermal transitions of the original textured, heat set and cyclic strained filaments were measured using differential scanning calorimetry from 25 to 250 ºC. Cyclic deformation induces an endo-exo transition at peak temperatures between 55 - 60 ºC that is not observed in the original textured and heat set multifilaments. There is another endo-exo transition with peak temperatures between 67 and 72 ºC in all filaments, the intensity of which varies according to texturing conditions, heat setting and cycle strain. Texturing conditions, heat setting and cyclic strain play a role in thermal transitions, the strain at breaking and elastic properties of the filaments. The crystallinity and magnitude of the endo-exo thermal events detected by DSC are related to the strain at breaking and elasticity of polylactide textured ...
You may also wish to search for items by Massalska-Arodz. 7 matching references were found. Rachwalska, M.; Massalska-Arodz, M.; Moscicki, J.K.; Jaich, A., Calorimetric study of NPOB, Mol. Cryst. Liq. Cryst., 1982, 80, 157-164. [all data] Bamezai, R.K.; Godlewska, M.; Massalska-arodz, M.; Sciesinski, J.; Witko, W., The adiabatic calorimetry study of the polymorphism of solid 4,4-di-n-butyloxyazoxybenzene, Phase Transitions, 1990, 27(2-3), 113-119. [all data] Mayer, J.; Witko, W.; Massalska-Arodz, M.; Williams, G.; Dabrowski, R., Polymorphism of right handed (S) 4-(2-Methylbutyl) 4´-Cyanobiphenyl, Phase Transitions, 1999, 69, 2, 199-213, https://doi.org/10.1080/01411599908208019 . [all data] Sciesinski, J.; Sciesinska, E.; Massalska, E.; Massalska-Arodz, M.; Wasiutynski, T.; Zielinski, P.M.; Witko, W., Polymorphism of righthanded octyloxycyanobiphenyl, IEEE Trans. Dielect. Electr. Insul., 2001, 8, 3, 522-526, https://doi.org/10.1109/94.933377 . [all data] Massalska-Arodz, M., Specific-heat ...
The outermost membrane of gram-negative bacteria is a lipopolysaccharide (LPS) rich bilayer assembly that acts as the first line of defense for bacterial cells in adverse physical and chemical environments. Besides the LPS, the outer membrane has radially extending O-antigen polysaccharide chains and β-barrel membrane proteins that make the bacterial membrane physiologically unique compared to the phospholipid cell membranes. To study the molecular complexity and dynamics of the LPS rich membrane, we have developed coarse grained parameter set for the outer membrane compatible with the Martini force field. The coarse grained model was benchmarked against available experimental and atomistic simulations data for properties such as membrane thickness, density profiles of the residues, area per lipid, gel to liquid-crystalline phase transition temperatures, order parameters, and radial distribution functions. More than 17 membrane compositions were studied with a combined simulation time of over 100
A chemical registry was created from a literature review and included characteristics relevant to XL such as molecular weight, carcinogenicity/mutagenicity, toxicity, hydrophobicity, and commercial availability. From this registry, compounds were then selected for efficacy screening using an ex vivo rabbit corneal cross-linking simulation set up. XL solution was administered via a corneal reservoir for 30 min in 0.1M NaHCO3 at either pH 7.4 or 8.5. The epithelium was left intact and 0.5% proparacaine was applied prior to XL. The control contralateral eye was treated identically with vehicle. Effectiveness of XL was based on shifts in thermal denaturation temperature (Tm) as measured by differential scanning calorimetry (Perkin-Elmer DSC 6000). Favorable DSC results were validated using biomechanical inflation tests with digital image correlation (DIC) as previously described by Myers et al.. ...
Gadolinium silicide (Gd5Si4) nanoparticles (NPs) exhibit different properties compared to their parent bulk materials due to finite size, shape, and surface effects. NPs were prepared by high energy ball-milling of the as-cast Gd5Si4ingot and size separated into eight fractions using time sensitive sedimentation in an applied dc magnetic field with average particle sizes ranging from 700 nm to 82 nm. The largest Gd5Si4 NPs order ferromagnetically at 316 K. A second anomaly observed at 110 K can be ascribed to a Gd5Si3 impurity. As the particle sizes decrease, the volume fraction of Gd5Si3 phase increases at the expense of the Gd5Si4 phase, and the ferromagnetic transition temperature of Gd5Si4 is reduced from 316 K to 310 K, while the ordering of the minor phase is independent of the particle size, remaining at 110 K.
The CMS hadronic calorimeter (HCAL) employs a plastic-scintillator-based endcap detector. The CMS HCAL Phase 1 upgrade involves installing silicon photomultipliers (SiPM) to measure light from scintillators in the detector. The SiPM signals are digitized by custom readout cards, called QIE cards, using the charge integration and encoder version 11 (QIE11) chip. The QIE cards for the HCAL endcap (HE) were tested and calibrated at FNAL. Then at CERN the QIE cards completed high radiation tests in the CHARM facility and muon/pion energy measurements in testbeam. Finally, the HE readout electronics were installed in CMS in 2018. The HCAL endcaps were calibrated using two Co-60 radiation sources. During physics data-taking in 2018, the HCAL online software (HCOS) configures and monitors the readout electronics to ensure data quality. This talk will summarize the testing, installation and commissioning of the HE Phase 1 upgrade readout system ...
LISA may be able to detect the gravitational waves from a first order phase transition at the electroweak scale. We present results from a large campaign of simulations studying a model of such phase transitions, and determine the shape of the power spectrum with unparalleled accuracy. We make concrete predictions of the detectability of sound waves from such a scenario, and note that an accurate measurement could place constraints on the underlying phase transition parameters.. ...
Journal of Shahid Sadoughi University of Medical Sciences ماهنامه علمی پژوهشی دانشگاه علوم پزشکی و خدمات بهداشتی درمانی شهید صدوقی یزد
I did an experiment using a calorimeter to determine the energy produced when certain salts are mixed with water. How do you calculate the energy absorbed when mixing salts with water that produce an endothermic reaction, make thing the water cold, but with regards to calorimetry? I dont know how to get the energy but I know how to get the molar enthalpy, but I am still confused, if I calculate just for energy using q=mct I feel like Im not taking into consideration everything regarding
The material contains several polymers and additives. It is important that each component has a similar melting point. To find the right formulation we use the DSC analysis and the Kofler hot stage ...
NFPA chapter 15 page 11 to page 15 DESIGN and INSTALLATION clause 4-4.3.2 VESSELS delineates;. (a) These rules for exposure protection contemplate emergency relieving capacity for vessles, based upon a maximum allowable heat input of 6,000 BTU per hour per sg ft (18,930 W/sq m) of exposed surface area. The density shall be increased to limit the heat absorption to a safe level in the event required emergency relieving capacity is not provided.. (b) Water shall be applied to VERTICAL or INCLINED vessel surfaces at a Net Rate of Not less that 0.25 Gallon per minutes per sq ft (10.17 Liter per minute per sq meter) of exposed un-insulated surface ...
Extramarks provides online study material for ICSE class 10 Calorimetry chapter. Practice physics icse board sample papers to score good marks in exams.
Dense protein clusters are known to play an important role in nucleation of protein crystals from dilute solutions. While these have generally been thought to be formed from a metastable phase, the observation of similar, if not identical, clusters above the critical point for the dilute-solution/strong-solution phase transition has thrown this into doubt. Furthermore, the observed clusters are stable for relatively long times. Because protein aggregation plays a central role in some pathologies, understanding the nature of such clusters is an important problem. One mechanism for the stabilization of such structures was proposed by Pan, Vekilov and Lubchenko and was investigated using a dynamical density functional theory model which confirmed the viability of the model. Here, we revisit that model and incorporate additional physics in the form of state-dependent reaction rates. We show by a combination of numerical results and general arguments that the state-dependent rates disrupt the ...
Calorimetry deals with the energetics of atoms, molecules, and phases and can be used to gather experimental details about one of the two roots of our knowledge about matter. The other root is structural science. Both are understood from the microscopic to the macroscopic scale, but the effort to learn about calorimetry has lagged behind structural science. Although equilibrium thermodynamics is well known, one has learned in the past little about metastable and unstable states. Similarly, Dalton made early progress to describe phases as aggregates of molecules. The existence of macromolecules that consist of as many atoms as are needed to establish a phase have led, however, to confusion between colloids (collections of microphases) and macromolecules which may participate in several micro- or nanophases. This fact that macromolecules can be as large or larger than phases was first established by Staudinger as late as 1920. Both fields, calorimetry and macromolecular science, found many ...
Abstract: We find an unexpected tetragonal-to-monoclinic-to-rhombohedral-to-cubic phase transition sequence induced by pressure, and a morphotropic phase boundary in a pure compound using first-principles calculations. Huge dielectric and piezoelectric coupling constants occur in the transition regions, comparable to those observed in the new complex single-crystal solid-solution piezoelectrics such as Pb(Mg$_{1/3}$Nb$_{2/3}$)O$_{3}$-PbTiO$_{3}$, which are expected to revolutionize electromechanical applications. Our results show that morphotropic phase boundaries and giant piezoelectric effects do not require intrinsic disorder, and open the possibility of studying this effect in simple systems ...
1B5X: Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six Ser --> Ala mutants.
Brief Summary Report of MHE Project Phenomenology and Controllability of New Exothermic Reaction between Metal and Hydrogen (Quote) https://www.researchgate.net/p…etween_Metal_and_Hydrogen
A new homologous series (ten compounds) of 2-hydroxy azo compounds SRn (where n:1-10) were synthesized. Their structures were elucidated using spectroscopic techniques such as IR (Infrared), 1H-NMR as well as elemental analysis. Mesomorphic properties and phase transitions were studied using polarized hot stage optical microscopy and differential scanning calorimetry (DSC), and are discussed as a function of the number of carbon atoms in the thioalkyl chain. It has been found that all compounds in the series are pure nematogens.
Differential scanning calorimeter[edit]. Main article: Differential scanning calorimetry. In a differential scanning ... Differential scanning calorimetry is a workhorse technique in many fields, particularly in polymer characterization. ... A modulated temperature differential scanning calorimeter (MTDSC) is a type of DSC in which a small oscillation is imposed upon ... Differential scanning calorimeters, isothermal micro calorimeters, titration calorimeters and accelerated rate calorimeters are ...
Differential scanning calorimetry". Retrieved 17 April 2017. Chupka, É. I.; Rykova, T. M. (1983). "Electrical properties of ... as determined as inflection point of the heat capacity-temperature curve recorded by differential scanning calorimetry (DSC). ... The phosphitylated sample is then scanned using liquide state 31P-NMR spectroscopy and the hydroxyl groups are quantified by ...
Differential scanning calorimetry, viscosity measurements, light scattering). Because of their amphiphilic structures, the ...
Thermogravimetry Differential thermal analysis Differential scanning calorimetry Danish, Muhammad; Ahmad, Nazir; Zahara, Nayab ...
... differential scanning calorimetry, thermogravimetric analysis; Electrophoresis; Field flow fractionation; X-ray diffraction; ...
"Detection of coating waxes on apples by differential scanning calorimetry". European Food Research and Technology 212.5 (2000) ...
This is due to the higher sensitivity of CL over conventional differential scanning calorimetry (CDS) methods, hence no need to ... These properties are typically found using differential scanning calorimetry (DSC). However, these options use elevated ...
Verification by Differential Scanning Calorimetry with an All-Inclusive Microcell". ACS Applied Materials & Interfaces. 9 (2): ...
To measure the heat flow differential scanning calorimetry can be used. Assuming that each bond formed during the crosslinking ...
"Using Differential Scanning Calorimetry for Biosimilarity and Batch-to-Batch Comparability". News Medical Net. 21 April 2017. " ...
Its existence has only recently been confirmed by differential scanning calorimetry. Okamoto H; Journal of Phase Equilibria, ...
This technique uses differential scanning calorimetry (DSC) to detect the phase changes. The signal detection relies on ... of the melting can be done by sensing the transient heat flows during phase transitions using differential scanning calorimetry ... Scanning curves and loops have been used to show that cryoporometry melting curves are prone to pore-pore cooperative effects ... "Studies of freezing-melting hysteresis in cryoporometry scanning loop experiments using NMR diffusometry and relaxometry", Chem ...
The crystallinity of the polymer can be measured through differential scanning calorimetry. For amorphous and semicrystalline ... A true workhorse for polymer characterization is thermal analysis, particularly Differential scanning calorimetry. Changes in ... Transmission Electron Microscopy in combination with staining techniques, but also Scanning Electron Microscopy, Scanning probe ... Crazes can be seen with transmission electron microscopy and scanning electron microscopy, and are typically engineered into a ...
I. Study of curing by differential scanning calorimetry and Fourier transform infrared". Journal of Polymer Science Part A: ...
Differential scanning calorimetry (DSC) is used to determine the thermal properties of polyanhydrides. Glass transition ...
The thermal stability can be measured by thermogravimetric analysis and differential scanning calorimetry. Polyesters are ...
Differential scanning calorimetry gives information on melting point together with its enthalpy of fusion. A basic melting ...
"Quantitative Description of Temperature Induced Self-Aggregation Thermograms Determined by Differential Scanning Calorimetry" ( ... equation can be exploited for the extraction of aggregation numbers of self-assembled micelles from differential scanning ... by isothermal titration calorimetry. Comparison with the Van 't Hoff value". Physical Chemistry Chemical Physics. 5 (12): 2625- ...
To measure the heat flow differential scanning calorimetry can be used.[9] ...
Differential scanning calorimetry (DSC) is another method industries use to examine properties of gelatinized starch. As water ...
Differential scanning calorimetry has shown that high temperature (69 °C) is required to unfold it. Phytic acid is the primary ...
Assays to detect adulteration with HFCS use differential scanning calorimetry and other advanced testing methods. In the ...
Differential scanning calorimetry (DSC) is an analytical technique used to examine thermodynamic properties of molecules. It ... differential scanning calorimetry (DSC), nuclear magnetic resonance which include 2HNMR and 31PNMR, thin layer chromatography ( ...
Differential scanning calorimetry can be used to quantify enthalpy change due to molecular structural relaxation. The term " ... Let the homogeneous differential equation: m d 2 y d t 2 + γ d y d t + k y = 0 {\displaystyle m{\frac {d^{2}y}{dt^{2}}}+\gamma ... which becomes the separable differential equation 1 − ( k + k ′ ) [ A ] + k ′ [ A ] 0 d [ A ] = d t {\displaystyle {1 \over -(k ...
The sf-TM experiments duplicate experiments that can be performed using differential scanning calorimetry (DSC). A limitation ... A second cooling scan followed by a third heating scan can be performed to check on the reliability of the prior scans. ... The second heating scan will differ from the first heating scan because of thermal relaxation during the first scan and the ... used to be consistent with modulated temperature differential scanning calorimetry (mt-DSC) and other situations when a ...
H-2 Nuclear Magnetic-Resonance and Differential Scanning Calorimetry." Biochemistry 29(2):451-464. v t e. ...
... a differential scanning calorimetry study". Biochemistry. 38 (14): 4464-4470. doi:10.1021/bi982828s. PMID 10194368. Reddy GB, ...
For calibration, an empty oven would also be heated during this process for differential scanning calorimetry. The difference ...
By differential scanning calorimetry (DSC), holo SOD1 unfolds by a two-state mechanism: from dimer to two unfolded monomers.[24 ...
Scanning electron microscope (SEM). *Transmission electron microscope (TEM). Thermochemistry. *Calorimeter *differential ... If a single detector, such as a photomultiplier tube or photodiode is used, the grating can be scanned stepwise (scanning ... It is then scanned through the sample and the reference solutions.. *Fractions of the incident wavelengths are transmitted ... In short, the sequence of events in a scanning spectrophotometer is as follows: *The light source is shone into a monochromator ...
"Predicting gelatinization temperature of starch/sweetener system for cake formulation by differential scanning calorimetry I. ...
"Differential Scanning Calorimetry Analysis of the Thermal Treatment of Ternary Mixtures of Ethylene Vinyl Acetate, Polyethylene ... A typical light scattering (or diffusion) optical technique, multiple light scattering coupled with vertical scanning, is the ...
... differential scanning calorimetry (DSC), UV-Vis absorption Spectroscopy, Fourier transform infra-red (FTIR), and ... scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), X-ray fluorescence (XRF), ...
J.C.W. Folmer, S. Franzen (2003). Study of polymer glasses by modulated differential scanning calorimetry in the undergraduate ...
In a scanning instrument, the signal produced in the detector during the course of the scan versus where the instrument is in ... This differential equation is the classic equation of motion for charged particles. Together with the particle's initial ... The analyzer can be used to select a narrow range of m/z or to scan through a range of m/z to catalog the ions present.[16] ... Boyd, Robert K. (1994). "Linked-scan techniques for MS/MS using tandem-in-space instruments". Mass Spectrometry Reviews. 13 (5- ...
Differential scanning calorimetry gives information on melting point together with its enthalpy of fusion. ...
... so the melting point is determined by finding the highest temperature of a differential scanning calorimetry chart. Perfectly ...
Differential scanning calorimetry is used to characterize the thermal properties of polymers, such as the glass transition ... represented as traces from differential scanning calorimetry. As the temperature increases, both amorphous and semicrystalline ...
a b ISO 11357-2: Plastics - Differential scanning calorimetry - Part 2: Determination of glass transition temperature (1999). ... The most frequently used definition of Tg uses the energy release on heating in differential scanning calorimetry (DSC, see ... Measurement of Tg (the temperature at the point A) by differential scanning calorimetry ... phonons in condensed matter are directly responsible for the thermal conductivity that levels out temperature differentials ...
Assays to detect adulteration with HFCS use differential scanning calorimetry and other advanced testing methods.[16][17] ...
... of the temperature and enthalpy of the solid-solid phase transition of caesium nitrate by differential scanning calorimetry". ...
... properties such as the glass transition temperature and melting point can be determined by differential scanning calorimetry ...
... of the temperature and enthalpy of the solid-solid phase transition of caesium nitrate by differential scanning calorimetry". ...
... is a technique closely related to isothermal titration calorimetry (ITC) and differential scanning calorimetry (DSC). In brief ...
The second method, differential scanning calorimetry (DSC), allows for more precise determination of phase transitions and ...
... differential scanning calorimetry (DSC), and deuterium nuclear magnetic resonance (2H NMR). Additionally, negative staining ...
X-ray scattering and differential scanning calorimetry". J. Chem. Soc., Faraday Trans. 92 (17): 3173-3182. doi:10.1039/ ...
Differential scanning calorimetry (DSC) ISO 11357-1:2009 General principles ISO 11357-2:2013 Determination of glass transition ... Helical scan recording - DDS-DC format using 60 m and 90 m length tapes ISO/IEC 11558:1992 Information technology - Data ... Helical scan recording - DATA/DAT format ISO 11323:2010 Iron ore and direct reduced iron - Vocabulary ISO/TR 11328:1994 ... Helical scan recording ISO/IEC 11321:1992 Information technology - 3,81 mm wide magnetic tape cartridge for information ...
Differential thermal analysis) (DTA) and (differential scanning calorimetry) (DSC): Analyzing the heating effect of polymer ... Journal of Thermal Analysis and Calorimetry, Vol. 67 (2002) 295~303. ...
... or coffee cup calorimeter Differential Scanning Calorimeter Reaction calorimeter see also Calorimeter or Calorimetry Entropy is ... Scanning acoustic microscope Scanning probe microscope Atomic force microscope (AFM) Scanning electron microscope Scanning ... Dilatometer Strain gauge Thiele tube Kofler bench Differential Scanning Calorimeter gives melting point and enthalpy of fusion ... Redox electrode Other values may be determined indirectly by calorimetry. Also by analyzing phase-diagrams. See also the ...
Differential scanning calorimetry (DSC) is a thermoanalytical technique in which the difference in the amount of heat required ... Differential scanning calorimetry can be used to measure a number of characteristic properties of a sample. Using this ... Using differential scanning calorimetry to study the stability to oxidation of samples generally requires an airtight sample ... Differential scanning calorimetry can also be used to obtain valuable thermodynamics information about proteins. The ...
Differential scanning calorimetry, or DSC, is a thermoanalytical technique in which the difference in the amount of heat ...
One of the major advantages of differential scanning calorimetry (DSC) is that it depends on heat measurements, which make ... Influence of transition rates and scan rate on kinetic simulations of differential scanning calorimetry profiles of reversible ... One of the major advantages of differential scanning calorimetry (DSC) is that it depends on heat measurements, which make ... Using Differential Scanning Calorimetry to Expedite the Development of Optimized Therapeutic Protein Formulations. ...
This is accomplished by means of differential scanning calorimetry (DSC). The technique makes use of the double melting point ... Determination of Degradation of Nylon 66 Using Differential Scanning Calorimetry. Published: 0 ... predictions, heat measurement, scanning, nylon 66, degradation, melting points, polyamide resins, brittleness, crystallization ... predictions, heat measurement, scanning, nylon 66, degradation, melting points, polyamide resins, brittleness, crystallization ...
Flash Differential Scanning Calorimetry revolutionizes rapid-scanning DSC. The Flash DSC 1 can analyze reorganization processes ... Temperature Scan DMA Measurements of Differently Vulcanized SBR Samples. Frequency Sweep DMA Measurements of Differently ... You are here: Home , Analytical Instruments , Thermal Analysis Excellence , Chip Calorimetry (Flash DSC) ... Safety analysis of a nitration reaction by DSC and reaction calorimetry. Safety is an important aspect in process development ...
Differential Scanning Calorimetry (DSC). Differential scanning calorimetry (DSC) is the most frequently used thermal analysis ... Differential Scanning Calorimetry (DSC). Glass transition temperature and crystallization determination by Differential ... Physics of Differential scanning calorimetry. Differences in heat flow arise when a sample absorbs or releases heat due to ... Differential scanning calorimetry (DSC) is the most frequently used thermal analysis tech-nique. DSC measures enthalpy changes ...
A method and apparatus for simultaneous differential scanning calorimetry and microdielectrometry is disclosed. The apparatus ... Differential scanning calorimeter. WO1998020314A3 *. Oct 31, 1997. Jul 2, 1998. Ta Instr Inc. Differential scanning calorimeter ... Differential Scanning Calorimetry (DSC) provides quantitative measurements of the instantaneous heat capacities and thermal ... 2 discloses a cross-sectional schematic view of a sample cell for simultaneous differential scanning calorimetry and ...
... Differential Scanning Calorimeter (DSC) analysis and ... Intertek provides Differential Scanning Calorimeter (DSC) thermal analysis for polymer and plastic research and development (R& ...
type.9 9.). Test Methods 11.1 Melting Characteristics by Thermal Analysis-Use differential scanning calorimetry (DSC) as ...
Associations of Calorimetry, Differential Scanning with chemical compounds. *Differential scanning calorimetry scans of cells ... Associations of Calorimetry, Differential Scanning with chemical compounds. *Gene context of Calorimetry, Differential Scanning ... Anatomical context of Calorimetry, Differential Scanning. *A differential scanning calorimetry study of acetylcholine receptor- ... and its stability was examined by differential scanning calorimetry [29].. *Differential scanning calorimetry was used to ...
See more than you ever thought possible with our advanced line of differential scanning calorimetry (DSC) solutions. Whether ... dynamic differential calorimetry, thermodynamic, and dynamic mechanical analysis. With this part number, this book is available ...
Learn about the principles of Differential Scanning Calorimetry (DSC). Differential Scanning Calorimetry (DSC) is a technique ...
Differential scanning calorimetry of the effects of temperature and humidity on phenol-formaldehyde resin cure. Polymer. Vol. ... Differential scanning calorimetry of the effects of temperature and humidity on phenol-formaldehyde resin cure ... A differential scanning calorimeter was employed to characterize the degree of resin cure in this study. Resin-impregnated ...
If you are a society or association member and require assistance with obtaining online access instructions please contact our Journal Customer Services team ...
Nonisothermal crystallization kinetics of in situ nylon 6/graphene composites by differential scanning calorimetry. Authors. * ... The nonisothermal crystallization kinetics was investigated by differential scanning calorimetry for the nylon 6/graphene ... Isothermal crystallization kinetics of in situ Nylon 6/graphene composites by differential scanning calorimetry, Polymer ... Journal of Thermal Analysis and Calorimetry, 2014, 118, 1, 197. CrossRef ...
Differential scanning calorimetry (DSC) - Part 2: Determination of glass transition temperature and glass transition step ... Plastics - Differential scanning calorimetry (DSC) - Part 2: Determination of glass transition temperature and glass transition ...
... differential scanning calorimetry, differential thermal analysis, hydrocarbons, oxidation, oxidation induction time (OIT), ... oxidation onset temperature (OOT), oxidative stability, pressure differential scanning calorimetry, ... e1 Standard Test Methods for Oxidation Onset Temperature of Hydrocarbons by Differential Scanning Calorimetry , ... of the oxidative properties of hydrocarbons by differential scanning calorimetry or pressure differential scanning calorimetry ...
MicroCal PEAQ-DSC is a highly sensitive, easy-to-use Differential Scanning Calorimeter (DSC) that provides insights into ... MicroCal PEAQ-DSC Automated is a highly sensitive, fully automated Differential Scanning Calorimeter (DSC) that provides ... UWS, Advanced Materials Characterisation Facility (AMCF) have installed their new bench-top Phenom XL Scanning Electron ... and ATA Scientific has been able to secure a 2 year placement of the bench-top Scanning Electron Microscope (Phenom SEM) for ...
Get Differential Scanning Calorimetry Supplies at Spectrum Chemical. SpectrumChemical.com carries a full line of fine chemicals ... Differential Scanning Calorimetry Supplies Differential Scanning Calorimetry Supplies. Spectrum offers laboratory grade ... Spectrum has the Differential Scanning Calorimetry Supplies solution for you. ... Differential Scanning Calorimetry Supplies from the industrys leading manufacturer Perkin Elmer. Whether you require a DSC ...
... differential scanning calorimetry (DSC) has been acknowledged as a novel tool for diagnosing and monitoring several diseases. ... Recently, differential scanning calorimetry (DSC) has been acknowledged as a novel tool for diagnosing and monitoring several ... Deconvolution analysis for classifying gastric adenocarcinoma patients based on differential scanning calorimetry serum ...
Using differential scanning calorimetry (DSC) and plate count (PC), growth of Escherichia coli was measured in four initial E. ... Growth measurement of Escherichia coli by differential scanning calorimetry. Villagómez Ibarra, José Roberto. 2014 ... Growth measurement of Escherichia coli by differential scanning calorimetry?, Esmeralda Rangel-Vargas, Carlos A. Gómez-Aldapa, ...
It was therefore of interest to investigate the possible application of differential scanning calorimetry (DSC) as a fast and ... investigation to group disparate batches of licit and illicit diazepam tablets using differential scanning calorimetry ... investigation to group disparate batches of licit and illicit diazepam tablets using differential scanning calorimetry S. Bibi ...
Differential scanning calorimetry studies revealed strong relationships between onset and enthalpy values of all acorn tissues ... Effects of desiccation on temperate recalcitrant seeds: differential scanning calorimetry, gas chromatography, electron ... Effects of desiccation on temperate recalcitrant seeds: differential scanning calorimetry, gas chromatography, electron ...
Differential scanning calorimetry of blood plasma for clinical diagnosis and monitoring. Exp Mol Pathol. 2009;86:186-91.PubMed ... The differential scanning calorimetry (DSC) method has been employed to compare changes in DSC profiles of blood sera in the ... Differential scanning calorimetry was applied to evaluate the effect of WBC on the response of elite cross-country skiers to ... Differential scanning calorimetry (DSC) was applied to compare changes in athletes blood serum during both sessions. Mean DSC ...
The electrochemical results were in close agreement with those deriving from a differentialscanning calorimetric study of the ...
Kinetics of Cold-Cap Reactions for Vitrification of Nuclear Waste Glass Based on Simultaneous Differential Scanning Calorimetry ... Kinetics of Cold-Cap Reactions for Vitrification of Nuclear Waste Glass Based on Simultaneous Differential Scanning Calorimetry ... the cold-cap reactions of a representative waste glass feed using both the simultaneous differential scanning calorimetry ...
Differential scanning calorimetry (DSC) unfolding trace of AxeA. The protein (0.6 mg ml−1) was heated in 50 mM sodium phosphate ... f5: Differential scanning calorimetry (DSC) unfolding trace of AxeA. The protein (0.6 mg ml−1) was heated in 50 mM sodium ... f5: Differential scanning calorimetry (DSC) unfolding trace of AxeA. The protein (0.6 mg ml−1) was heated in 50 mM sodium ... Mentions: The thermal stability of AxeA was further investigated by differential scanning calorimetry (DSC). The observed ...
  • The first adiabatic differential scanning calorimeter that could be used in biochemistry was developed by P. L. Privalov and D. R. Monaselidze in 1964 at Institute of Physics in Tbilisi, Georgia. (wikipedia.org)
  • Intertek provides Differential Scanning Calorimeter (DSC) thermal analysis for polymer and plastic research and development (R&D), quality control, product and process development, and other applications. (intertek.com)
  • A differential scanning calorimeter was employed to characterize the degree of resin cure in this study. (usda.gov)
  • 1.2 Test Method A- A differential scanning calorimeter (DSC) is used at ambient pressure, of one atmosphere of oxygen. (astm.org)
  • There are two common types of Adiabatic calorimeter- Accelerating Rate Calorimetry (ARC) and Adiabatic Pressure Dewar Calorimetry (ADC). (azosensors.com)
  • A calorimeter is an object used for calorimetry , or the process of measuring the heat of chemical reactions or physical changes as well as heat capacity . (wikipedia.org)
  • The isothermal crystallization kinetics of nylon 6/graphene (NG) composites prepared by in situ polymerization was investigated by differential scanning calorimetry. (polymer.cn)
  • In the present paper, the overall amorphous-crystallization transformation kinetics of chalcogenide Se 79 Te 20 Pb 1 alloy has been reported using differential scanning calorimetry technique under non-isothermal conditions at three different heating rates (5, 10 and 15 °C/min). (niscair.res.in)
  • Adhvaryu, A, Perez, JM & Singh, ID 1999, ' Application of quantitative NMR spectroscopy to oxidation kinetics of base oils using a pressurized differential scanning calorimetry technique ', Energy and Fuels , vol. 13, no. 2, pp. 493-498. (elsevier.com)
  • [ citation needed ] Reaction calorimetry can also be used to determine maximum heat release rate for chemical process engineering and for tracking the global kinetics of reactions. (wikipedia.org)
  • By observing the difference in heat flow between the sample and reference, differential scanning calorimeters are able to measure the amount of heat absorbed or released during such transitions. (wikipedia.org)
  • Hence, these kind of instruments are termed as differential scanning calorimeters. (news-medical.net)
  • This thesis shows that the equilibrium transition temperatures of materials can be accurately determined using two developed methodologies designed to be used with differential scanning calorimeters. (hud.ac.uk)
  • Differential scanning calorimeters measure this heat uptake. (malvernpanalytical.com)
  • Calorimeters are a tool used in calorimetric testing (calorimetry), which is the process of measuring heat, enthalpy or specific heat capacity for both chemical reactions and physical changes in a given system. (azosensors.com)
  • Differential scanning calorimeters, isothermal micro calorimeters, titration calorimeters and accelerated rate calorimeters are among the most common types. (wikipedia.org)
  • The binding of insulin to the G-quadruplexes formed by the consensus sequence of the insulin-linked polymorphic region (ILPR) was investigated with differential scanning calorimetry (DSC) and isothermal titration calorimetry (ITC). (whiterose.ac.uk)
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  • One of the major advantages of differential scanning calorimetry (DSC) is that it depends on heat measurements, which make characterization of native biomolecules possible. (news-medical.net)
  • We studied the cold-cap reactions of a representative waste glass feed using both the simultaneous differential scanning calorimetry thermogravimetry (DSC-TGA) and the thermogravimetry coupled with gas chromatography-mass spectrometer (TGA-GC-MS) as complementary tools to perform evolved gas analysis (EGA). (osti.gov)
  • Thermogravimetry-coupled with differential scanning calorimetry, quadrupole mass spectrometry, and Fourier-transform infrared spectroscopy (TG-DSC-QMS-FTIR)-was applied to monitor the thermal stability (in an N 2 pyrolytic atmosphere) and chemical properties of natural polymers, fulvic (FA) and humic acids (HA), isolated from chemically different soils. (figshare.com)
  • The STA is a combination of the methods Differential Scanning Calorimetry (DSC) and Thermogravimetry (TG). (fraunhofer.de)
  • There are two MicroCal PEAQ-DSC Differential Scanning Calorimetry instruments available, both of which are designed for use in the regulated biopharmaceutical environment. (malvern.com)
  • Differential scanning calorimetry, thermogravimetric analysis and differential thermal analysis. (dal.ca)
  • The operation of these systems is based on the measurement of the heat capacity (Cp) of a protein sample solution while scanning up or down in temperature. (news-medical.net)
  • At the time of scanning, the measurement of excess (differential) heat capacity of the protein is carried out with respect to a carefully matched solvent reference cell. (news-medical.net)
  • Measurement principles Differential scanning calorimetry (DSC) measures the difference between the heat flows from the sample and reference sides of a sensor as a function of temperature or time. (mt.com)
  • UWS, Advanced Materials Characterisation Facility (AMCF) have installed their new bench-top Phenom XL Scanning Electron Microscope (SEM). (atascientific.com.au)
  • The UWS through collaboration with Phenom-World BV, and ATA Scientific has been able to secure a 2 year placement of the bench-top Scanning Electron Microscope (Phenom SEM) for the shared Centralised Research Facilities to support both research and teaching. (atascientific.com.au)
  • The scanning electron microscope uses a focused beam of high energy electrons to create a signal at the surface of solid specimens. (bristol.ac.uk)
  • Microstructure analysis by scanning electron microscope (SEM) revealed relatively higher size of MCCS with smooth and round morphology. (frontiersin.org)
  • The particle size, morphology, molecular weight, and thermal performance of nanoparticles containing the phase change material (PCM) were measured by dynamic light scattering, transmission electron microscopy, gel permeation chromatography, and differential scanning calorimetry, respectively. (scielo.br)
  • A more recent and extremely useful investigative tool is the scanning electron microscope (SEM). (fisk.edu)
  • The surface of the specimen to be examined is scanned with an electron beam, and the reflected (or back-scattered) beam of electrons is collected, then displayed at the same scanning rate on a cathode ray tube (similar to a TV screen). (fisk.edu)
  • The enthalpy for denaturation of a protein can be directly measured using calorimetry. (news-medical.net)
  • Differential scanning calorimetry (DSC) was used to study the denaturation of this lectin as a function of pH that ranged from 2.0 to 3.0. (eurekamag.com)
  • 31 P-NMR measurements utilizing Ga +3 as a shifting reagent in comparison to HPLC determinations, theoretical calculations and differential scanning calorimetry (DSC) studies of various liposomal ALN formulations. (omicsonline.org)
  • Need to subtract water effects from ΔCp measurements by use of reference (buffer-buffer) scan. (psu.edu)
  • Differential scanning calorimetry and X-ray diffraction measurements showed that the majority of SLNs possessed less ordered arrangements of crystals than the corresponding bulk lipids, which was favorable for increasing the drug loading capacity. (pubmedcentralcanada.ca)
  • 1.1 These test methods describe the determination of the oxidative properties of hydrocarbons by differential scanning calorimetry or pressure differential scanning calorimetry under linear heating rate conditions and are applicable to hydrocarbons, which oxidize exothermically in their analyzed form. (astm.org)
  • 1.1 This test method covers the determination of the overall kinetic parameters for exothermic reactions using the Flynn/Wall/Ozawa method and differential scanning calorimetry. (bsigroup.com)
  • Differential scanning calorimetry, or DSC, is a thermoanalytical technique in which the difference in the amount of heat required to increase the temperature of a sample and reference is measured as a function of temperature. (purdue.edu)
  • The use of these methods allows for the instrument, which is typically scanning in nature to produce accurate temperature values under near equilibrium conditions. (hud.ac.uk)
  • In the literature, however, non-linear behavior of the measured onset temperature is reported for the case of high scanning rates and the use of small samples. (usda.gov)
  • This sets up a voltage, which is converted into power and is used control the Peltier to return ΔT (the temperature differential) to 0°C. Alternatively, the cells can be allowed to reach thermal equilibrium passively through conduction. (malvernpanalytical.com)
  • Their cross-linking effects on porcine and rabbit eyes were measured using differential scanning calorimetry (DSC), expressed as the change/difference in melting temperature (Δ T m ) compared with the control. (portlandpress.com)
  • Glass transition temperature measured by differential scanning calorimetry, structural changes measured by X-ray diffraction, and molecular interactions measured by Fourier transform infrared spectroscopy showed changes in MN matrix properties, but they did not correlate with IPV activity changes during storage. (nih.gov)
  • Differential Scanning Calorimetry (DSC) is a technique for understanding the stability of proteins and other biomolecules. (water-technology.net)
  • Thermotoga maritima AxeA represents the most thermostable acetyl xylan esterase known to date.Differential scanning calorimetry analysis of the thermal stability of AxeA corroborated its extreme heat resistance.A multi-phasic unfolding behaviour was found, with two apparent exothermic peaks at approximately 100-104 °C and 107.5 °C. (nih.gov)
  • The thermal stability of AxeA was further investigated by differential scanning calorimetry (DSC). (nih.gov)
  • Differential Scanning Calorimetry (DSC) is a technique used to characterize the stability of a protein or other biomolecule directly in its native form. (materials-talks.com)
  • Differential scanning calorimetry studies revealed strong relationships between onset and enthalpy values of all acorn tissues and percent germination, as did regressions involving moisture content and seed germination. (usda.gov)
  • Bomb calorimetry is typically used to measure the enthalpy of combustion in a reaction. (azosensors.com)
  • Further investigations into the use of high sensitivity differential scanning calorimetry as a means of predicting drug-excipient interactions. (springer.com)
  • Whether you require a DSC Calibration reference Material or a Diamond DSC Loading Tool, Spectrum has the Differential Scanning Calorimetry Supplies solution for you. (spectrumchemical.com)
  • Differential scanning calorimetry (DSC), isothermal stress testing-Fourier transform infrared spectroscopy (IST-FTIR), isothermal stress testing-high-performance liquid chromatography, and powder X-ray diffraction (PDRX) were used as screening techniques for assessing the compatibility of tobramycin with some currently employed ophthalmic excipients. (springer.com)
  • Spectrum offers laboratory grade Differential Scanning Calorimetry Supplies from the industry's leading manufacturer Perkin Elmer. (spectrumchemical.com)
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  • Differential scanning calorimetry (DSC) is a relatively rapid direct and nonperturbing thermodynamic technique for studying the thermotropic phase behavior of hydrated lipid dispersions and of reconstituted lipid model and biological membranes. (schoolbag.info)
  • To see more than youር ever seen from Differential Scanning Calorimetry (DSC), turn to PerkinElmer, where DSC was invented. (perkinelmer.com)
  • By the use of differential scanning calorimetry (DSC), and fluorescence efflux studies, details about the liptin interactions can be investigated. (wichita.edu)
  • The reference sample should have a well-defined heat capacity over the range of temperatures to be scanned. (wikipedia.org)
  • There are two different types of DSC: Heat-flux DSC which measures the difference in heat flux between the sample and a reference and Power differential DSC which measures the difference in power supplied to the sample and a reference. (wikipedia.org)
  • Heat resistance of viable but nonculturable Escherichia coli cells determined by differential scanning calorimetry. (edu.mx)
  • In Protein-ligand Interactions: hydrodynamics and calorimetry, pp. 287-318. (nih.gov)
  • An alternative technique, which shares much in common with DSC, is differential thermal analysis (DTA). (wikipedia.org)
  • Differential scanning calorimetry (DSC) is the most frequently used thermal analysis technique. (mt.com)
  • and resulting uncertainty in the accuracy of analytical and numerical models has been addressed by the development of a new technique using differential scanning calorimetry (DSC). (uwaterloo.ca)
  • One such technique currently attracting attention is differential scanning calorimetry (DSC). (bioprocessintl.com)
  • Reaction calorimetry is a non-invasive, non-destructive, real-time technique that yields important kinetic data, as well as providing safety data for scale-up and hazardous processes. (azosensors.com)
  • The crystallization of the amorphous form of this compound was investigated using Differential Scanning Calorimetry. (illinois.edu)
  • Using differential scanning calorimetry (DSC) and plate count (PC), growth of Escherichia coli was measured in four initial E. coli cell concentrations cultured in tryptic soy broth (TSB) at 35C. (edu.mx)
  • Both Fourier transform-infrared spectroscopy (FT-IR) and differential scanning calorimetry (DSC) established the complete dispersion of the nanoemulsion in the polymeric matrices of the prepared nanoemulgel and NFs. (dovepress.com)
  • Differential scanning calorimetry (DSC) provides a quantitative evaluation of the calorific energy associated with a chemical or physical change in a chemical substance. (scirp.org)
  • Differential scanning calorimetry (DSC) has been used to study the thermal resistance of culturable bacteria but has never been used to study VBNC cells. (edu.mx)
  • The goal of this study was to compare the thermal properties of these new archwires with their uncoated counterparts before and after clinical use via differential scanning calorimetry (DSC). (marquette.edu)
  • We even epub differential scanning and measure to evaluate developed by primal-dual physics. (tobiasdiekmann.de)
  • Differential scanning calorimetry (DSC) provides easy screening for thermal hazard evaluation. (scirp.org)
  • Results demonstrate differential scanning calorimetry (DSC) is a reliable quantitative method for straight-forward and rapid evaluation of ligand binding constants for HSA and modified derivatives. (usda.gov)
  • Please make Many that epub Differential and consumers are infected on your scan and that you motivate also Completing them from preference. (glogau-online.de)
  • Differential Scanning Calorimetry applied to bitumen: Results of the RILEM NBM TG1 Round Robin test. (nynas.com)
  • Compared with those parameters determined by titration calorimetry, the results highlight the potentiality of DSC to estimate binding parameters in multiligand binding proteins. (meta.org)
  • Mura P, Furlanetto S, Cirri M, Maestrelli F, Marras AM, Pinzauti S. Optimization of glibenclamide tablet composition through the combined use of differential scanning calorimetry and d-optimal mixture experimental design. (springer.com)
  • 5. A pharmaceutical composition comprising an amorphous solid-state form of (R)-(+)-7-(3-amino-2,3,4,5,6,7-hexahydro-1H-azepin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid characterized by a DSC (differential scanning calorimetry) melting peak at about 267-272° C. (freepatentsonline.com)
  • The transformation temperatures and phase transformations of these wires were determined in the as-received condition and after 4 to 12 weeks in the oral cavity by differential scanning calorimetry. (marquette.edu)
  • [click here to continue…] This epub differential scanning provides bulk power PDE and e sonars for new challenging current( APO) solvation of marine herb, interest, and differences. (tobiasdiekmann.de)
  • In this sense, the application of the theory of macromolecular unfolding linked to ligand binding to differential scanning calorimetry (DSC) has proved to be a useful tool to simultaneously characterize the energetics of unfolding and binding. (meta.org)