A plant genus of the family CLUSIACEAE. Members contain costatolide, calanolides and 4-phenylfuranocoumarins (FUROCOUMARINS).
The outer layer of the woody parts of plants.
A type of COUMARINS with added pyran ring(s).
Six-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives. Various polyneuropathies are caused by hexane poisoning.
The mangosteen plant family (sometimes classified as Guttiferae; also known as Hypericaceae) of the order THEALES, subclass Dilleniidae, class Magnoliopsida. It includes trees and shrubs with resinous, sticky sap, usually with broad-ended, oblong, leathery leaves with a strong, central vein, flowers with many stamens.
A group of XANTHENES that contain a 9-keto OXYGEN.
The soapberry plant family of the order Sapindales, subclass Rosidae, class Magnoliopsida. Some members contain SAPONINS.
Synthetic or naturally occurring substances related to coumarin, the delta-lactone of coumarinic acid.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.

Sudden exposure to solar UV-B radiation reduces net CO(2) uptake and photosystem I efficiency in shade-acclimated tropical tree seedlings. (1/17)

Tree seedlings developing in the understory of the tropical forest have to endure short periods of high-light stress when tree-fall gaps are formed, and direct solar radiation, including substantial UV light, reaches the leaves. In experiments simulating the opening of a tree-fall gap, the response of photosynthesis in leaves of shade-acclimated seedlings (Anacardium excelsum, Virola surinamensis, and Calophyllum longifolium) to exposure to direct sunlight (for 20-50 min) was investigated in Panama (9 degrees N). To assess the effects of solar UV-B radiation (280-320 nm), the sunlight was filtered through plastic films that selectively absorbed UV-B or transmitted the complete spectrum. The results document a strong inhibition of CO(2) assimilation by sun exposure. Light-limited and light-saturated rates of photosynthetic CO(2) uptake by the leaves were affected, which apparently occurred independently of a simultaneous inhibition of potential photosystem (PS) II efficiency. The ambient UV-B light substantially contributed to these effects. The photochemical capacity of PSI, measured as absorbance change at 810 nm in saturating far-red light, was not significantly affected by sun exposure of the seedlings. However, a decrease in the efficiency of P700 photooxidation by far-red light was observed, which was strongly promoted by solar UV-B radiation. The decrease in PSI efficiency may result from enhanced charge recombination in the reaction center, which might represent an incipient inactivation of PSI, but contributes to thermal dissipation of excessive light energy and thereby to photoprotection.  (+info)

Inocalophyllins A, B and their methyl esters from the seeds of Calophyllum inophyllum. (2/17)

Fractionation of the ethanolic extract of the seeds of Calophyllum inophyllum L. has resulted in the isolation of four novel pyranocoumarin derivatives, designated as inocalophyllins A (1), B (2) and their methyl esters (3, 4) in addition to the known calophyllolide. The structures of these compounds have been determined on the basis of spectroscopic analysis including MS, heteronuclear single quantum coherence (HSQC), heteronuclear multiple bond connectivity (HMBC) and two dimensional incredible natural abundance double quantum transfer experiment (2D-INADEQUATE). Two new methylated products, 5 and 6 were also prepared by methylation of compounds 1 and 2, respectively.  (+info)

Trypanocidal constituents in plants 3. Leaves of Garcinia intermedia and heartwood of Calophyllum brasiliense. (3/17)

The constituents of the leaves of Garcinia intermedia and heartwood of Calophyllum brasiliense were investigated based on their trypanocidal activity against epimastigotes of Trypanosoma cruzi, the etiologic agent of Chagas' disease. As the active components, the polyisoprenylated benzophenone derivative guttiferone A and the xanthone 8-desoxygartanin were isolated along with the biflavonoids podocarpusflavone A and amentoflavone, and friedelin from the former. Three xanthones, jacareubin, 6-deoxyjacareubin, and 1,3,5,6-tetrahydroxy-2-(3-methyl-2-butenyl)xanthone from the latter showed activity. The trypanocidal activity of these compounds against trypomastigotes, an infectious form of T. cruzi, was examined as well as gossypol, berberine chloride, and harmine for comparison.  (+info)

Chromanones and dihydrocoumarins from Calophyllum blancoi. (4/17)

Chromatographic fractionation of the acetone extract of the seeds of Calophyllum blancoi yielded six pyranochromanone derivatives; apetalic acid (1), isoapetalic acid (2), apetalic acid methyl ester (3), apetalic acid 5-O-acetate (4), isoapetalic methyl ester (5), and isoapetalic acid 5-O-acetate (6). In addition, one new dihydrocoumarin derivative, isorecedensolide (7), was also isolated together with recedensolide (8). The structures of the isolated compounds were established through analysis of NMR spectral data including 2D techniques as well as other physical and spectroscopic methods. Compounds 3, 4, 5, 7, and 8 showed mild activity against KB (human oral epidermoid carcinoma) and Hela (human cervical epitheloid carcinoma) tumor cell lines.  (+info)

HIV-1 inhibitory compounds from Calophyllum brasiliense leaves. (5/17)

The hexane, acetone and methanol extracts of Calophyllum brasiliense leaves were fractionated following a three bioassay guide: high HIV-1 RT inhibition, low cytotoxicity on MT2 cells and high inhibition of HIV-1 IIIb/LAV replication. This led to the isolation of three anti HIV-1 dipyranocoumarins: calanolides A and B and soulattrolide. In contrast, other isolated compounds such as apetalic acid, isoapetalic acid, a structural isomer of isoapetalic acid, friedelin, canophyllol and amentoflavone were devoid of HIV-1 RT inhibitory activity. Calanolide C was also obtained as a natural product and showed moderate inhibitory properties.  (+info)

Bioactive pyranoxanthones from the roots of Calophyllum blancoi. (6/17)

Phytochemical investigation of the roots of Calophyllum blancoi growing in Taiwan resulted in the isolation of three new pyranoxanthones, blancoxanthone (1), acetyl blancoxanthone (2) and 3-hydroxyblancoxanthone (3), in addition to two known pyranoxanthones, pyranojacaeubin (4) and caloxanthone (5). Structural characterization of the isolated compounds was determined by spectral analyses especially 2-D NMR. Biological study of the isolated xanthones revealed that blancoxanthone (1) exhibited significant anti-coronavirus activity.  (+info)

Evaluation of the relaxant action of some Brazilian medicinal plants in isolated guinea-pig ileum and rat duodenum. (7/17)

PURPOSE: The present study aimed to evaluate the possible antispasmodic activity in vitro of methanolic extracts (ME) of six Brazilian medicinal plants. METHODS: The extracts were evaluated on isolated guinea-pig ileum and rat duodenum preparations. RESULTS: Rubus imperialis, Maytenus robusta, Ipomoea pes caprae and Epidendrum mosenii did not inhibit the contractile response elicited by acetylcholine on guinea-pig ileum. On the other hand, ME from Calophyllum brasiliense and Cynara scolymus exhibited significant inhibitory activity for the contractile response elicited by acetylcholine on guinea-pig ileum and on rat duodenum in a noncompetitive and concentration-dependent manner. CONCLUSIONS: The current study suggests that, of the six medicinal plants evaluated, only the ME of Calophyllum brasiliense and Cynara scolymus show probable antispasmodic activity, confirming and justifying their use in folk medicine for the treatment of intestinal disorders.  (+info)

Caloxanthones O and P: two new prenylated xanthones from Calophyllum inophyllum. (8/17)

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"Calophyllum" is a genus of plants that belongs to the family Calophyllaceae. These evergreen trees and shrubs are native to tropical regions of the world, particularly in Southeast Asia, Africa, and the Pacific Islands. The name "Calophyllum" comes from the Greek words "kalos," meaning beautiful, and "phyllon," meaning leaf, which refers to the attractive leaves of these plants.

Many species of Calophyllum have medicinal properties. For example, the bark, leaves, and seeds of Calophyllum inophyllum, also known as Alexandrian laurel or Indian laurel, have been used in traditional medicine to treat a variety of conditions, including skin diseases, rheumatism, and diarrhea. The oil extracted from the seeds of this plant, called "tamanu oil," is believed to have anti-inflammatory, antibacterial, and antioxidant properties and is used in cosmetics and skincare products.

However, it's important to note that while some species of Calophyllum have medicinal uses, they should not be used as a substitute for professional medical advice, diagnosis, or treatment. It's always recommended to consult with a healthcare provider before using any natural remedies or supplements.

I'm sorry for any confusion, but "Plant Bark" is not a term with a specific medical definition. In general, the bark refers to the outermost covering of a tree or other plant, which serves as protection and provides a barrier against external threats. It is composed of layers including the inner bark (phloem), which transports nutrients throughout the plant, and the outer bark (periderm), which is made up of dead cells that form a protective layer.

While some plants or plant parts do have medicinal properties and are used in various forms of traditional or alternative medicine, "Plant Bark" by itself does not have any specific medical connotations. If you're referring to a specific type of plant bark with potential medicinal uses, please provide more details so I can give a more accurate response.

Pyranocoumarins are a type of chemical compound that are found in various plants. They are characterized by a furanocoumarin structure, which is a combination of a furan ring (a five-membered aromatic ring containing four carbon atoms and one oxygen atom) and a coumarin ring (a six-membered aromatic ring containing two carbonyl groups).

Pyranocoumarins are known to have various biological activities, including phototoxic, antimicrobial, and anti-inflammatory effects. They can also inhibit certain enzymes, such as cytochrome P450 enzymes, which are involved in drug metabolism. Some pyranocoumarins have been studied for their potential use in cancer therapy, although more research is needed to fully understand their mechanisms of action and safety profiles.

Heptanes are a group of hydrocarbons that are composed of straight-chain or branched arrangements of six carbon atoms and are commonly found in gasoline. They are colorless liquids at room temperature with a characteristic odor. In a medical context, exposure to heptanes can occur through inhalation, skin contact, or ingestion, and can cause symptoms such as headache, dizziness, nausea, and irritation of the eyes, nose, and throat. Chronic exposure has been linked to more serious health effects, including neurological damage and cancer. Proper handling and use of heptanes, as well as adequate ventilation, are important to minimize exposure and potential health risks.

Clusiaceae is a family of flowering plants that includes trees, shrubs, and herbs. It was previously known as Guttiferae. The family includes several economically important plants, such as those that produce edible fruits (such as mangosteen) and those that yield valuable resins and dyes (such as garcinia).

The plants in Clusiaceae are characterized by their production of a yellow or orange latex, which contains various chemical compounds with potential medicinal properties. Some species have been used in traditional medicine to treat a variety of conditions, including skin diseases, gastrointestinal disorders, and infections. However, more research is needed to confirm the safety and efficacy of these uses.

Xanthones are a type of chemical compound that are found in various plants and fruits. They have a variety of potential health benefits, including anti-inflammatory, antioxidant, and anticancer properties. Some research suggests that xanthones may help to protect against chronic diseases such as heart disease and cancer, but more studies are needed to confirm these effects. Xanthones can be found in small amounts in a variety of foods, including mangosteen fruit, blackberries, and turmeric. They are also available in supplement form.

I apologize for any confusion, but "Sapindaceae" is not a medical term. It is a taxonomic category in botany, referring to the soapberry family of plants, which includes around 150 genera and 2000 species of trees, shrubs, and vines. Some examples of plants that belong to this family are the lychee, longan, and soapberry.

If you have any medical terms or concepts that you would like me to define or explain, please let me know!

Coumarins are a class of organic compounds that occur naturally in certain plants, such as sweet clover and tonka beans. They have a characteristic aroma and are often used as fragrances in perfumes and flavorings in food products. In addition to their use in consumer goods, coumarins also have important medical applications.

One of the most well-known coumarins is warfarin, which is a commonly prescribed anticoagulant medication used to prevent blood clots from forming or growing larger. Warfarin works by inhibiting the activity of vitamin K-dependent clotting factors in the liver, which helps to prolong the time it takes for blood to clot.

Other medical uses of coumarins include their use as anti-inflammatory agents and antimicrobial agents. Some coumarins have also been shown to have potential cancer-fighting properties, although more research is needed in this area.

It's important to note that while coumarins have many medical uses, they can also be toxic in high doses. Therefore, it's essential to use them only under the guidance of a healthcare professional.

A plant extract is a preparation containing chemical constituents that have been extracted from a plant using a solvent. The resulting extract may contain a single compound or a mixture of several compounds, depending on the extraction process and the specific plant material used. These extracts are often used in various industries including pharmaceuticals, nutraceuticals, cosmetics, and food and beverage, due to their potential therapeutic or beneficial properties. The composition of plant extracts can vary widely, and it is important to ensure their quality, safety, and efficacy before use in any application.

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