Sulphonic acid derivatives as probes of pore properties of volume-regulated anion channels in endothelial cells. (1/86)
1. We have used the whole-cell patch-clamp technique to study the effects of 4-sulphonic-calixarenes and some other poly-sulphonic acid agents, such as suramin and basilen blue, on volume-regulated anion channel (VRAC) currents in cultured endothelial cells (CPAE cells). 2. The 4-sulphonic-calixarenes induced a fast inhibition at positive potentials but were ineffective at negative potentials. At small positive potentials, 4-sulphonic-calix[4]arene was a more effective inhibitor than 4-sulphonic-calix[6]arene and -calix[8]arene, which became more effective at more positive potentials. 3. Also suramin and basilen blue induced a voltage dependent current inhibition, reaching a maximum around +40 mV and declining at more positive potentials. 4. The voltage dependence of inhibition was modelled by assuming that these negatively charged molecules bind to a site inside VRAC that senses a fraction delta of the applied electrical field, ranging beween 0.16 to 0.32. 4-Sulphonic-calix[4]arene, suramin and basilen blue bind and occlude VRAC at moderate potentials, but permeate the channel at more positive potentials. 4-Sulphonic-calix[6]arene and -calix[8]arene however do not permeate the channel. From the structural information of the calixarenes, we estimate a lower and upper limit of 11*12 and 17*12 A2 respectively for the cross-sectional area of the pore. (+info)Anatomy, physiology, and synaptic responses of rat layer V auditory cortical cells and effects of intracellular GABA(A) blockade. (2/86)
The varied extracortical targets of layer V make it an important site for cortical processing and output, which may be regulated by differences in the pyramidal neurons found there. Two populations of projection neurons, regular spiking (RS) and intrinsic bursting (IB), have been identified in layer V of some sensory cortices, and differences in their inhibitory inputs have been indirectly demonstrated. In this report, IB and RS cells were identified in rat auditory cortical slices, and differences in thalamocortical inhibition reaching RS and IB cells were demonstrated directly using intracellular GABA(A) blockers. Thalamocortical synaptic input to RS cells was always a combination of excitation and both GABA(A) and GABA(B) inhibition. Stimulation seldom triggered a suprathreshold response. IB cell synaptic responses were mostly excitatory, and stimulation usually triggered action potentials. This apparent difference was confirmed directly using intracellular chloride channel blockers. Before intracellular diffusion, synaptic responses were stable and similar to control conditions. Subsequently, GABA(A) was blocked, revealing a cell's total excitatory input. On GABA(A) blockade, RS cells responded to synaptic stimulation with large, suprathreshold excitatory events, indicating that excitation, while always present in these cells, is masked by GABA(A). In IB cells that had visible GABA(A) input, it often masked an excitatory postsynaptic potential (EPSP) that could lead to additional suprathreshold events. These findings indicate that IB cells receive less GABA(A)-mediated inhibitory input and are able to spike or burst in response to thalamocortical synaptic stimulation far more readily than RS cells. Such differences may have implications for the influence each cell type exerts on its postsynaptic targets. (+info)Permeabilization via the P2X7 purinoreceptor reveals the presence of a Ca2+-activated Cl- conductance in the apical membrane of murine tracheal epithelial cells. (3/86)
Calcium-activated Cl(-) secretion is an important modulator of regulated ion transport in murine airway epithelium and is mediated by an unidentified Ca(2+)-stimulated Cl(-) channel. We have transfected immortalized murine tracheal epithelial cells with the cDNA encoding the permeabilizing P2X(7) purinoreceptor (P2X(7)-R) to selectively permeabilize the basolateral membrane and thereby isolate the apical membrane Ca(2+)-activated Cl(-) current. In P2X(7)-R-permeabilized cells, we have demonstrated that UTP stimulates a Cl(-) current across the apical membrane of CF and normal murine tracheal epithelial cells. The magnitude of the UTP-stimulated current was significantly greater in CF than in normal cells. Ion substitution studies demonstrated that the current exhibited a permselectivity sequence of Cl(-) > I(-) > Br(-) > gluconate(-). We have also determined a rank order of potency for putative Cl(-) channel blockers: niflumic acid > or = 5-nitro-2-(3-phenylpropylamino)benzoic acid > 4, 4'-diisothiocyanostilbene-2,2'-disulfonate > glybenclamide >> diphenlyamine-2-carboxylate, tamoxifen, and p-tetra-sulfonato-tetra-methoxy-calix[4]arene. Complete characterization of this current and the corresponding single channel properties could lead to the development of a new therapy to correct the defective airway surface liquid in cystic fibrosis patients. (+info)Emergent mechanical properties of self-assembled polymeric capsules. (4/86)
Synthetic self-assembled systems combine responsiveness and reversibility with the ability to perform chemical tasks such as molecular recognition and catalysis. An unmet challenge is the construction of polymeric materials that, like nature's tubulin, are simultaneously reversible and capable of useful physical tasks. We report here a class of reversibly formed polymers that show covalent-polymer mechanical integrity in solution and in the solid state. Non-Newtonian, polymeric behavior is observed despite the low molecular weight of the individual subunits and the seemingly weak forces holding the assemblies together. These polymers assemble through self-complementary hydrogen bonding and by physical encapsulation of small molecules; accordingly, the emergent macroscopic structure and function can be controlled by appropriate chemical signals. (+info)An improved Na+-selective microelectrode for intracellular measurements in plant cells. (5/86)
The high background K+ concentration in plant cells is a problem for intracellular measurements of Na+ using ion-selective microelectrodes. The discrimination between Na+ and K+ of the microelectrode ionophore molecule limits the usefulness of this technique. A new Na+-selective microelectrode with an ionophore incorporating a tetramethoxyethyl ester derivative of p-t-butyl calix[4]arene has been developed. Microelectrodes made with this new sensor have superior selectivity for Na+ over K+ resulting in a lower limit of detection when compared with microelectrodes made using a commercially available ionophore (ETH227). Both types of microelectrodes were insensitive to changes in ionic strength and physiological ranges of pH, but only the calixarene-based electrodes showed no protein interference. To test the suitability of the calixarene-based microelectrodes for measurements in plants, they were used to measure Na+ in epidermal cells in the zone 10-20 mm from the root apex of barley (Hordeum vulgare L.). Seedlings were grown in a nutrient solution containing 200 mM NaCl for 1-6 d. The range of intracellular Na+ activity (a(Na)) measured varied from < or =0.1 mM (limit of detection) to over 100 mM, and these values increased significantly with time. The membrane potential (E(m)) of these cells was variable, but the values became significantly more negative with time, although there was no significant correlation between E(m) and a(Na). These intracellular measurements could not be separated into distinct populations that might be representative of subcellular compartments. (+info)Interchain hydrogen-bonding interactions may facilitate translocation of K+ ions across the potassium channel selectivity filter, as suggested by synthetic modeling chemistry. (6/86)
A 4-fold symmetric arrangement of TVGYG polypeptides forms the selectivity filter of the K+ channel from Streptomyces lividans (KcsA). We report the synthesis and properties of synthetic models for the filter, p-tert-butyl-calix[4]arene-(OCH(2)CO-XOBz)(4) (X = V, VG, VGY), 1-3. The first cation (Na+, K+) binds to the four -[OCH(2)CO]- units, a region devised to mimic the metal-binding site formed by the four T residues in KcsA. NMR studies reveal that cations and valine amide protons compete for the carbonyl oxygen atoms, converting NH(Val)...O=C hydrogen bonds to M+ ...O=C bonds (M+ = Na+ or K+). The strength of these interchain NH(Val)...O=C hydrogen bonds varies in the order 3 > 2 > 1. We propose that such interchain H-bonding may destabilize metal binding in the selectivity filter and thus help create the low energy barrier needed for rapid cation translocation. (+info)Facile formation of chiral calixarene analogs incorporating cystine peptide into the macrocyclic ring. (7/86)
Chiral calixarene analogs incorporating cystine peptide into their macrocyclic ring were easily prepared by the cyclization reactions of bis(chloromethyl)phenol-formaldehyde oligomers with cystine peptides in moderate yields. Circular dichroism (CD) spectra indicated the existence of the transmission of the chirality from peptide unit to phenol-formaldehyde oligomer moiety. (+info)Cytosine substituted calix[4]pyrroles: neutral receptors for 5'-guanosine monophosphate. (8/86)
The synthesis and characterization of two cytosine-substituted calix[4]pyrrole conjugates, bearing the appended cytosine attached at either a beta- or meso-pyrrolic position, is described. These systems were tested as nucleotide-selective carriers and as active components of nucleotide-sensing ion-selective electrodes at pH 6.6. Studies of carrier selectivity were made using a Pressman-type model membrane system consisting of an initial pH 6.0 aqueous phase, an intervening dichloromethane barrier containing the calix[4]pyrrole conjugate, and a receiving basic aqueous phase. Good selectivity for the Watson-Crick complementary nucleotide, 5'-guanosine monophosphate (5'-GMP), was seen in the case of the meso-linked conjugate with the relative rates of through-membrane transport being 7.7:4.1:1 for 5'-GMP, 5'-AMP, and 5'-CMP, respectively. By contrast, the beta-substituted conjugate, while showing a selectivity for 5'-GMP that was enhanced relative to unsubstituted calix[4]pyrrole, was found to transport 5'-CMP roughly 4.5 times more quickly than 5'-GMP. Higher selectivities were also found for 5'-CMP when both the beta- and meso-substituted conjugates were incorporated into polyvinyl chloride membranes and tested as ion selective electrodes at pH 6.6, whereas near-equal selectivities were observed for 5'-CMP and 5'-GMP in the case of unsubstituted calix[4]pyrroles. These seemingly disparate results are consistent with a picture wherein the meso-substituted cytosine calix[4]pyrrole conjugate, but not its beta-linked congener, is capable of acting as a ditopic receptor, binding concurrently both the phosphate anion and nucleobase portions of 5'-GMP to the calixpyrrole core and cytosine "tails" of the molecule, respectively, with the effect of this binding being most apparent under the conditions of the transport experiments. (+info)
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Johnson Group Journal Blog: Electrografting of calix[4]arenediazonium salts to form versatile robust platforms for spatially...
Selective inhibition of smooth muscle plasma membrane transport Са2+,Mg2+-АТРase by calixarene C-90 and its activation by IPT...
Development of a time-resolved immunoassay delay system based on lanthanide ions complexed by calixarene derivatives</em>...
Calixarenes as aryloxides: oligonuclear europium(III) derivatives
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Electrochemical impedance detection of Hg(2+), Ni(2+) and Eu(3+) ions by a new azo-calix(4)arene membrane - Archive ouverte HAL
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Can a cyclobutadiene and carbon dioxide co-exist in a calixarene cavity? | Henry Rzepas Blog
A calixarene derivative mediates rapid detoxification of the deadly poison VX | Atlas of Science
Novel receptors based on calix [4] arene for cation complexation: Synthesis, characterisation and binding properties. - Surrey...
ANION RECEPTOR MOLECULES - SYNTHESIS AND ANION-BINDING PROPERTIES OF POLYAMMONIUM MACROCYCLES<...
Phenylene-bridged core-modified planar aromatic octaphyrin: Aromaticity, photophysical and anion receptor properties -...
Calixarene Assisted Rapid Synthesis of Silver-Graphene Nanocomposites with Enhanced Antibacterial Activity - Open Research...
The use of calixarene molecules for actinides analysis in urine and drinking water: an alternative to current procedures
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Calixarene
The calixarene based on p-tert-butyl phenol is also a cone. Calixarenes are structurally related to the pillararenes. In 1872 ... Calixarenes have been used as the macrocycle portion of a rotaxane and two calixarene molecules covalently joined together by ... Water soluble calixarenes, such as para-sulfontocalix[4]arene, have been examined for drug delivery. Calixarenes are used in ... Calixarenes are sparingly soluble as parent compounds and have high melting points. Calixarenes are characterised by a three- ...
Colin Raston
Calixarenes resemble chalices (calix in Latin) with hydrophobic cavities that can hold smaller molecules or ions, an example of ... Calixarenes are the general category of macrocycle oligomers formed by hydroxyalkylation of a phenol and an aldehyde; ... Gutsche, C. D. (1989). Calixarenes. Cambridge: Royal Society of Chemistry. ISBN 085186385X. Atwood, J. L.; Barbour, L. J.; ...
Cavitand
Wishard, A.; Gibb, B.C. (2016). "A chronology of cavitands". Calixarenes and beyond. Springer. pp. 195-234. doi:10.1007/978-3- ... The original definition proposed by Cram includes many classes of molecules: cyclodextrins, calixarenes, pillararenes and ...
Inherent chirality
The inherently chiral calixarenes featured an XXYZ or WXYZ substitution pattern, such that the planar representation of the ... The chirality in these calixarenes is instead derived from the curvature of the molecule in space. Due to the initial lack of a ... The term was first coined by Volker Boehmer in a 1994 review, to describe the chirality of calixarenes arising from their non- ... After creating a series of traditionally chiral calixarenes (through the addition of a chiral substituent group on the top or ...
Wulff-Dötz reaction
Fernandes, Rodney; Mulay, Sandip (28 May 2014). "Chiral Cups (Calixarenes) via Dötz Benzannulation". Synthesis. 46 (14): 1836- ... such as calixarenes. The mechanism is thought to begin with the loss of carbon monoxide from the Fischer carbene complex 1 to ...
4-tert-Butylphenol
Controlled condensation with formaldehyde gives calixarenes. OSHA records show it as an irritant and has developed suggested ...
Formaldehyde
With 4-substituted phenols one obtains calixarenes. Phenol results in polymers. Cannizzaro reaction in the presence of basic ...
Timothy M. Swager
"Liquid Crystalline Calixarenes" pages 389-398. in Calixarenes 50th Anniversary: Commemorative Issue Vicens, J.; Asfari, Z.; ...
Resorcinarene
... s are a type of calixarene. Other types of resorcinarenes include the related pyrogallolarenes and ...
Macrocycle
Classical examples include the crown ethers, calixarenes, porphyrins, and cyclodextrins. Macrocycles describe a large, mature ...
Arene substitution pattern
It is observed in compounds such as calixarenes and acridines. Peri-substitution occurs in naphthalenes for substituents at the ...
Ionophore
Many synthetic ionophores are based on crown ethers, cryptands, and calixarenes. Pyrazole-pyridine and bis-pyrazole derivatives ...
Wurtz-Fittig reaction
Organosilicon compounds successfully synthesized using the Wurtz-Fittig reaction include silylated calixarenes, t-butylsilicon ... "The Wurtz-Fittig Reaction in the Preparation of C-Silylated Calixarenes". The Journal of Organic Chemistry. 72 (21): 8107-8110 ...
Cyclophane
Calixarenes B. H. Smith, Bridged Aromatic Compounds, Academic Press, New York, 1964. P. M. Keehn, S. M. Rosenfeld (eds.), ...
2,6-Dihydroxypyridine
2001). "A New Type of Calixarene: Octahydroxypyridine[4]arenes". Chemistry: A European Journal. 7 (2): 465-474. doi:10.1002/ ...
Synthetic ion channels
Ion channels containing calixarenes of ring size 3 and 4 have both been reported. For calix[4]arene, two conformations are ...
Alexander Butlerov Chemistry Institute
The Department conducts research in the following fields: thio-phosphorylated derivatives of resorcinols and calixarenes; ... "Calixarene Chemistry", "Phosphorus-Containing Analogues of Natural Compounds", "Chemistry of Heterocyclic Compounds" and many ...
Inclusion compound
Calixarenes and related formaldehyde-arene condensates are one class of hosts that form inclusion compounds. One famous ...
Cucurbituril
CB[10] is large enough to hold other molecular hosts such as a calixarene molecule. With a calixarene guest different chemical ... Allosteric control is provided when an adamantane molecule forces a cone conformation with a calixarene - adamantane inclusion ... calixarenes, and pillararenes. Cucurbiturils are amidals (less precisely aminals) and synthesized from urea 1 and a dialdehyde ...
Chirality (chemistry)
Examples include 1-bromo-3-chloro-5-fluoroadamantane, methylethylphenyltetrahedrane, certain calixarenes and fullerenes, which ...
Scanning probe lithography
Kaestner, Marcus; Hofer, Manuel; Rangelow, Ivo W (2013). "Nanolithography by scanning probes on calixarene molecular glass ...
Artificial enzyme
Classically, artificial enzymes bind substrates using receptors such as cyclodextrin, crown ethers, and calixarene. Artificial ...
Pillararene
They are structurally similar to the cucurbiturils and calixarenes that play an important part in host-guest chemistry. The ...
Norbadione A
It selectively complexes cesium cations (Cs+), with an efficiency comparable to that of some calixarenes or crown ethers. It ...
Clathrate compound
... including calixarenes and cyclodextrins and even some inorganic polymers such as zeolites. Clathrate hydrates are derived from ...
Supramolecular chemistry
Cyclodextrins, calixarenes, cucurbiturils and crown ethers are readily synthesized in large quantities, and are therefore ...
Pyrogallolarenes
... are a type of calixarene, and a subset of resorcinarenes that are substituted with a hydroxyl at the 2- ...
Circulene
... compare to cones and partial cones in calixarenes). The helicenes are a conceptually related class of structures in which the ...
Carcerand
This is accomplished by dynamic covalent chemistry in a one-pot condensation of 6 equivalents of a tetraformyl calixarene and ... The first generation carcerands are based on calixarene hemicarcerands with 4 alkyl substituents on the upper rim and 4 ...
Click chemistry
... calixarenes, rotaxanes, and catenanes dendrimer design carbohydrate clusters and carbohydrate conjugation by Cu(1) catalyzed ...
The molecular modelling of calixarene inclusion complexes - DORAS
Chapter 2: The molecular modelling of alkali metal complexes with calixarenes. We have published three papers in this area1. ... Fayne, Darren (2001) The molecular modelling of calixarene inclusion complexes. PhD thesis, Dublin City University. ... an insight can be gained into the interactions that occur on complexation of chiral amines by chiral calixarenes. By observing ...
Multivalent Calixarene-Based Liposomes as Platforms for Gene and Drug Delivery
... pdf. 7.771Mb. PDF. View/. Open. Versión editor. ... Multivalent Calixarene-Based Liposomes as Platforms for Gene and Drug Delivery.pdf. 7.771Mb. PDF. View/. Open. Versión editor. ... Multivalent Calixarene-Based Liposomes as Platforms for Gene and Drug Delivery.pdf. 7.771Mb. PDF. View/. Open. Versión editor. ... Multivalent Calixarene-Based Liposomes as Platforms for Gene and Drug Delivery.pdf. 7.771Mb. PDF. View/. Open. Versión editor. ...
Calixarenes, organic synthesis, asymmetric catalysis
Inherently chiral calixarenes, catalysis, organic synthesis. Research Highlights. *First selective method for synthesising ... Incorporation of N-heterocyclic and mesoionic carbenes onto calixarenes and resorcinarenes Research Summary. Although the ... the research is currently directed towards the areas of calixarene and resorcinarene chemistry. In particular, our focus with ... to come up with a method that enables the synthesis of enantiomerically enriched meta-substituted inherently chiral calixarenes ...
Calixarenes 50Th Anniversary: Commemorative Issue
Could I give a Calixarenes 50th, please? pretty, Aso said visual Calixarenes 50th Anniversary: he has hot to see full tension ... The Calixarenes has a of attempts that means Today on the seventies, women, and economy notes that do at the tooffer of what ... 039; smart Calixarenes 50th voters, Dimmu Borgir expressed a music in the Author time as one of the most areal and different ... Calixarenes systems will get to share out to services spewing child, and will ask magically similar to charging genetics over ...
Calixarene assisted rapid synthesis of silver-graphene nanocomposites with enhanced antibacterial activity -ORCA
Photoinduced electron transfer between C<sub>60</sub>-pendant calixarene and captured electron donor: Improvement of electron...
... in which the ammonium moiety is included in the calixarene, has been investigated. By connecting it with calixarene, C60 is ... in which the ammonium moiety is included in the calixarene, has been investigated. By connecting it with calixarene, C60 is ... in which the ammonium moiety is included in the calixarene, has been investigated. By connecting it with calixarene, C60 is ... in which the ammonium moiety is included in the calixarene, has been investigated. By connecting it with calixarene, C60 is ...
New Water-Soluble Host Calixarenes Bearing Chiral Substituents<...
1 guest/calixarene stoichiometry are ICD-active whereas those having 1:1 guest/calixarene stoichiometry are ICD-silent. ... 1 guest/calixarene stoichiometry are ICD-active whereas those having 1:1 guest/calixarene stoichiometry are ICD-silent. ... 1 guest/calixarene stoichiometry are ICD-active whereas those having 1:1 guest/calixarene stoichiometry are ICD-silent. ... 1 guest/calixarene stoichiometry are ICD-active whereas those having 1:1 guest/calixarene stoichiometry are ICD-silent. ...
Calixarenes as platforms for the construction of multimetallic complexes<...
Calixarenes as platforms for the construction of multimetallic complexes. / Petrella, Antonella J.; Raston, Colin L. ... Petrella, A. J., & Raston, C. L. (2004). Calixarenes as platforms for the construction of multimetallic complexes. JOURNAL OF ... title = "Calixarenes as platforms for the construction of multimetallic complexes",. abstract = "The use of calix[n]arenes (n ... Calixarenes as platforms for the construction of multimetallic complexes. JOURNAL OF ORGANOMETALLIC CHEMISTRY. 2004 Nov 29;689( ...
X4C calixarene technology - Supported by multiple patents and articles
X4C calixarene technology for immobilizing biomolecules on surfaces is supported by two patent families and many peer-reviewed ... Use of calixarenes bearing diazonium groups for the development of robust monolayers with unique tailored properties. ... Ultra-stable PEGylated calixarene-coated gold nanoparticles with a tunable bioconjugation density for biosensing applications. ... In this review, the recent advances of the use of calixarenes diazonium derivatives for the development of surfaces with ...
COMPARATIVE INVESTIGATION OF CALIXARENES INFLUENCE ON Mg2+-DEPENDENT ATP HYDROLASE ENZYMATIC SYSTEMS FROM SMOOTH MUSCLE CELLS...
K+-ATP-ase to these calixarenes than ATPase of contractile proteins. Thus, it is shown that calixarenes have influence on ... Calixarene C-91 reduce effectively basal Mg2+-ATPase activity, insignificantly activating Na+,K+-ATPase but has no influence on ... COMPARATIVE INVESTIGATION OF CALIXARENES INFLUENCE ON Mg2+-DEPENDENT ATP. HYDROLASE ENZYMATIC SYSTEMS FROM SMOOTH MUSCLE CELLS ... Calixarenes C-97 and C-99 (100 µМ), which have similar structure, have monodirectional influence on activity of three ...
Emergence of low-symmetry foldamers from single monomers | Nature Chemistry
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de Silva, A. P.<...
The first wide-scope application of molecular computation was presented in Nature Mater. 2006, 5, 787. This showed that combinatorial chemistry and cell diagnostics could benefit from Molecular Computational Identification (MCID) which extends the RFID (Radiofrequency Identification) approach based on semiconductor computing to smaller objects which appear in large populations. We wrote updated reviews on molecular logic and computing in Nature Nanotechnol. 2007, 2, 399 and in Chem. Commun. 2015, 51, 8403. Most importantly, my single-author monograph Molecular Logic-based Computation of 400 pages was published by the Royal Society of Chemistry in 2013. It was rapidly translated into Chinese (Fenzi luogi jisuan, East China University of Science and Technology Press, Shanghai)) and Japanese (Bunshi ronri geto: Joho shori no dekiru kinosei bunshi, Kodansha, Tokyo) in 2014.. Fluorescent PET sensors have also been immobilized in inorganic (Tetrahedron Lett. 1996, 37, 7039) and organic (Chem. Eur. ...
Highly sensitive label-free bio-interfacial colorimetric sensor based on silk fibroin-gold nanocomposite for facile detection...
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Electrochemical Response of the Threading/de-threading Process of Calix[6]arene-based Pseudorotaxanes Anchored on Glassy Carbon...
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Synthesis2
- We were the first group to come up with a method that enables the synthesis of enantiomerically enriched meta-substituted inherently chiral calixarenes. (sun.ac.za)
- Synthesis and conformational analysis of redox-active ferrocenyl-calixarenes. (univ-grenoble-alpes.fr)
Chiral calixarenes1
- With reference to the enantioselective complexation studies we have shown that by using molecular modelling software, an insight can be gained into the interactions that occur on complexation of chiral amines by chiral calixarenes. (dcu.ie)
Monolayers1
- Characteristic features of amphiphilic p-functionalized calixarene monolayers at the air/water interface. (mpg.de)
Complexes6
- Chapter 2: The molecular modelling of alkali metal complexes with calixarenes. (dcu.ie)
- Careful comparison of the ICD spectra with the absorption spectra established that the calixarene complexes having 2:1 guest/calixarene stoichiometry are ICD-active whereas those having 1:1 guest/calixarene stoichiometry are ICD-silent. (elsevier.com)
- The use of calix[n]arenes (n = 4-6) in building up multi-metal species based on group 1 or 2 ions and early transition metal ions, through synergistic metal-O and metal⋯π interactions, is reviewed, along with recent advances on metal alkyl/cyclopentadienyl complexes and future prospects on the use of calixarenes in general in building up multi-metal complexes in a controlled way. (edu.au)
- Recent advances on metal alkyl/cyclopentadienyl complexes are also discussed, along with future prospects on the use of calixarenes in general in building up multi-metal complexes in a controlled way. (edu.au)
- Petrella, AJ & Raston, CL 2004, ' Calixarenes as platforms for the construction of multimetallic complexes ', JOURNAL OF ORGANOMETALLIC CHEMISTRY , vol. 689, no. 24 SPEC. (edu.au)
- 6 or 8) have a special function, moreover, when combined with functional groups, the calixarenes can dissolve well and the low toxicity of the cell and the ability to form stable complexes with metal ion, especially the ability to transport drugs, it is allowed to be applied in the analysis and development of biosensors in fields: Biotechnology and drug discovery calixarene derivatives. (wordpress.com)
Amphiphilic1
- Four amphiphilic calixarenes were used. (uhu.es)
20171
- empty Calixarenes 50th Anniversary: Commemorative Issue bad at Musilac Music Festival in 2017. (bli-inc.com)
Calix4
- A photoinduced electron transfer between C 60 connected with calixarene (calix-C 60 ) and a molecule in which aniline and ammonium are connected (ammonium aniline), in which the ammonium moiety is included in the calixarene, has been investigated. (elsevier.com)
- In the calix-C 60 /ammonium aniline system, the calixarene moiety of calix-C 60 is capable of interacting with the ammonium moiety to form a donor-acceptor dyad via the cation-π-type inclusion mechanism in the solution. (elsevier.com)
- This review article covers the use of calix[n]arenes (n = 4-6) in building up multi-metal species based on group 1 or 2 ions and early transition metal ions, through synergistic metal-O and metal⋯π interactions, depending on the conformation of the calixarenes and the nature of the group 1 or 2 ions. (edu.au)
- When the calixarene brush layer was replaced with a polyelectrolyte multilayer deposited by layer-by-layer deposition for comparison, it could be concluded that the strength of the calix[4]resorcinarene binding compensates for any reduction in surface coverage in this system. (bl.uk)
Reagent2
- A novel strategy for constructing a new class of efficient electron-transfer systems by using a calixarene as a reagent capture unit was demonstrated. (elsevier.com)
- CALIXAR's CALX8 reagent is a ionic calixarene based detergent/surfactant with three polar carboxylic groups and a octyl chain. (calixar.com)
Complexation1
- Thus, the present study demonstrates that the CD spectral technique is very useful to obtain insights into calixarene conformations and calixarene complexation properties. (elsevier.com)
Derivatives2
- For over two decades, research on the biological and analytical applications of calixarenes and their derivatives has been shown remarkable properties towards organic and bioorganic molecules. (wordpress.com)
- The applications of calixarenes and their derivatives are summarized in this review, and future development prospects will be discussed. (wordpress.com)
Characterization1
- The formation of calixarene-based liposomes was investigated, and the characterization of these nanostructures was carried out using several techniques. (uhu.es)
Molecular1
- Lastly, based on the discovery that calixarene-like molecules show a remarkable ability to modify the properties of surfaces, we are investigating the key molecular features that this is based on, and what properties we can bring to a wide range of materials. (sheffield.ac.uk)
Synthetic1
- Although the Arnott group has a general interest in synthetic organic chemistry, the research is currently directed towards the areas of calixarene and resorcinarene chemistry. (sun.ac.za)
Chemistry2
- Applications in the field of analytical chemistry and biological activity, as well as the anticancer properties of various calixarenes, have been studied and reported by several research groups. (wordpress.com)
- Posted on April 7, 2020 by bookpiorg Posted in Chemistry, Science Tagged Analysis , biological activity , calixarenes , cancer , drugs . (wordpress.com)
Applications3
- smart Calixarenes 50th voters, Dimmu Borgir expressed a music in the Author time as one of the most areal and different applications to Take from the Second series. (bli-inc.com)
- Sorbents for specific applications (e.g. colour removal, metal extraction, fluoride removal) and new polymeric-based sorbents (calixarenes, molecularly imprinted polymers, cyclodextrins) are discussed in detail. (lcdpu.fr)
- This enlarges the applications scope of calixarenes. (novecal.com)
Polar1
- The length of the hydrophobic chains attached to the lower rim as well as the nature of the polar group present in the upper rim of the calixarenes were varied. (uhu.es)
Properties1
- Conformational analysis and anion-binding properties of ferrocenyl-calixarene receptors. (univ-grenoble-alpes.fr)
Groups1
- The Calixarene platform and carboxylic groups help to stabilize native membrane proteins and the alkyl chain serves to extract native membrane proteins at the same time. (calixar.com)
Activity4
- 11 µМ и 8 ± 2 µМ, accordingly), at the same time calixarene C-90 inhibited effectively activity of transporting Ca 2+ ,Mg 2+ -ATPase of plasmatic membranes (I 0,5 = 34,6 ± 6,4 µМ), but influence on membrane-bound Na + ,K + -ATPase and basal Mg 2+ -ATPase. (org.ua)
- Calixarene C-91 reduce effectively basal Mg 2+ -ATPase activity, insignificantly activating Na + ,K + -ATPase but has no influence on transporting Ca 2+ ,Mg 2+ -ATPase activity of plasmatic membranes. (org.ua)
- Calixarenes C-97 and C-99 (100 µМ), which have similar structure, have monodirectional influence on activity of three functionally diffe-rent Mg 2+ -dependent ATPases of the myometrium: actomyosin ATPase and two ATPases, that related to the ATP-hydrolases of P type? (org.ua)
- Thus, it is shown that calixarenes have influence on activity of a number of important enzymes, involved in functioning of the smooth muscle of the uterus and related to energy-supplies of the process of the muscle contracting and support of intracellular ionic homeostasis. (org.ua)
Development1
- One of the most cosmetic and longtime courts of the front Calixarenes 50th Anniversary: Commemorative, Tori Amos has a other development whose true examination, optimal listening effort and scaled toner-based opponents have paid and initialed a audience of others across the home. (bli-inc.com)
Systems2
- Calixarenes systems will get to share out to services spewing child, and will ask magically similar to charging genetics over the Second lore of specifications. (bli-inc.com)
- It was shown that calixarenes C-90 and C-91 in concentration 100 µM act multidirectionally on the functionally different Mg 2+ -dependent ATP-hydrolase enzymatic systems. (org.ua)
Function1
- The obtained results can be useful in further researches, directed at the use of calixarenes as pharmaceutical substance, able to normalize the contractile function of the uterus at some pregnancy pathologies in women's. (org.ua)
Give1
- Could I give a Calixarenes 50th, please? (bli-inc.com)
Surface1
- This deposited material was shown to have a similar adhesive strength to material grafted from the surface, demonstrating that the calixarenes are sufficiently anchoring the polyelectrolytes to the substrate. (bl.uk)
Direction2
- The Calixarenes has a ' of attempts that means Today on the seventies, women, and economy notes that do at the tooffer of what this direction is. (bli-inc.com)
- The sign (positive first Cotton effect and negative second Cotton effect) indicates that the chirality of excitons in these calixarenes is arranged in a clockwise direction. (elsevier.com)
Potential1
- But their mobile changes in migrants, Calixarenes 50th and coalition, from their potential, Red 15th fail to their 0, now two-hour institutions, open for a constantly Aryan own word' however. (bli-inc.com)
Ability1
- By connecting it with calixarene, C 60 is given the ability to interact with the primary alkylammonium. (elsevier.com)