A species of the genus VESIVIRUS infecting cats. Transmission occurs via air and mechanical contact.
A family of RNA viruses infecting a broad range of animals. Most individual species are restricted to their natural hosts. They possess a characteristic six-pointed starlike shape whose surfaces have cup-shaped (chalice) indentions. Transmission is by contaminated food, water, fomites, and occasionally aerosolization of secretions. Genera include LAGOVIRUS; NORWALK-LIKE VIRUSES; SAPPORO-LIKE VIRUSES; and VESIVIRUS.
Virus diseases caused by CALICIVIRIDAE. They include HEPATITIS E; VESICULAR EXANTHEMA OF SWINE; acute respiratory infections in felines, rabbit hemorrhagic disease, and some cases of gastroenteritis in humans.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.
A species of GAMMARETROVIRUS causing leukemia, lymphosarcoma, immune deficiency, or other degenerative diseases in cats. Several cellular oncogenes confer on FeLV the ability to induce sarcomas (see also SARCOMA VIRUSES, FELINE).
A genus of the family CALICIVIRIDAE associated with worldwide sporadic outbreaks of GASTROENTERITIS in humans. The first recorded outbreak was in human infants in Sapporo, Japan in 1977. The genus is comprised of a single species, Sapporo virus, containing multiple strains.
A species of LENTIVIRUS, subgenus feline lentiviruses (LENTIVIRUSES, FELINE) isolated from cats with a chronic wasting syndrome, presumed to be immune deficiency. There are 3 strains: Petaluma (FIP-P), Oma (FIP-O) and Puma lentivirus (PLV). There is no antigenic relationship between FIV and HIV, nor does FIV grow in human T-cells.
The type species in the genus NOROVIRUS, first isolated in 1968 from the stools of school children in Norwalk, Ohio, who were suffering from GASTROENTERITIS. The virions are non-enveloped spherical particles containing a single protein. Multiple strains are named after the places where outbreaks have occurred.
Acquired defect of cellular immunity that occurs in cats infected with feline immunodeficiency virus (FIV) and in some cats infected with feline leukemia virus (FeLV).
A species in the genus LAGOVIRUS which causes hemorrhagic disease, including hemorrhagic septicemia, in rabbits.
A species of CORONAVIRUS infecting cats of all ages and commonly found in catteries and zoos. Cats are often found carrying the virus but only a small proportion develop disease. Feline coronavirus and Feline infectious peritonitis virus (FIPV) are virtually the same virus in genetic and antigenetic terms, and are morphologically indistinguishable. Since they only differ in their disease potential (with FIPV causing a more serious illness), they are considered biotypes of each other.
Inactivation of viruses by non-immune related techniques. They include extremes of pH, HEAT treatment, ultraviolet radiation, IONIZING RADIATION; DESICCATION; ANTISEPTICS; DISINFECTANTS; organic solvents, and DETERGENTS.
A genus of the family CALICIVIRIDAE comprised of species infecting a wide range of organisms. Most members of this genus can be readily propagated in cell culture (as opposed to other genera of Caliciviridae). The type species is VESICULAR EXANTHEMA OF SWINE VIRUS.
The type species of the genus VESIVIRUS infecting pigs. The resulting infection is an acute febrile disease which is clinically indistinguishable from FOOT AND MOUTH DISEASE. Transmission is by contaminated food.
A genus in the family CALICIVIRIDAE, associated with epidemic GASTROENTERITIS in humans. The type species, NORWALK VIRUS, contains multiple strains.
A highly contagious DNA virus infection of the cat family, characterized by fever, enteritis and bone marrow changes. It is also called feline ataxia, feline agranulocytosis, feline infectious enteritis, cat fever, cat plague, and show fever. It is caused by FELINE PANLEUKOPENIA VIRUS or the closely related MINK ENTERITIS VIRUS or CANINE PARVOVIRUS.
INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER.
Species of GAMMARETROVIRUS isolated from fibrosarcoma in cats. The viruses are actually recombinant feline leukemia viruses (FeLV) where part of the genome has been replaced by cellular oncogenes. It is unique to individuals and not transmitted naturally to other cats. FeSVs are replication defective and require FeLV to reproduce.
A calicivirus infection of swine characterized by hydropic degeneration of the oral and cutaneous epithelia.
Common coronavirus infection of cats caused by the feline infectious peritonitis virus (CORONAVIRUS, FELINE). The disease is characterized by a long incubation period, fever, depression, loss of appetite, wasting, and progressive abdominal enlargement. Infection of cells of the monocyte-macrophage lineage appears to be essential in FIP pathogenesis.
A genus of the family CALICIVIRIDAE, associated with infections in rabbits and hares, responsible for epidemics with high mortality. RABBIT HEMORRHAGIC DISEASE VIRUS is the type species.
A species of PARVOVIRUS infecting cats with a highly contagious enteric disease. Host range variants include mink enteritis virus, canine parvovirus (PARVOVIRUS, CANINE), and raccoon parvovirus. After infecting their new hosts, many of these viruses have further evolved and are now considered distinct species.
A family of small RNA viruses comprising some important pathogens of humans and animals. Transmission usually occurs mechanically. There are nine genera: APHTHOVIRUS; CARDIOVIRUS; ENTEROVIRUS; ERBOVIRUS; HEPATOVIRUS; KOBUVIRUS; PARECHOVIRUS; RHINOVIRUS; and TESCHOVIRUS.
The outer protein protective shell of a virus, which protects the viral nucleic acid.
Rendering pathogens harmless through the use of heat, antiseptics, antibacterial agents, etc.
Virus diseases caused by the PICORNAVIRIDAE.
A neoplastic disease of cats frequently associated with feline leukemia virus infection.
The complete genetic complement contained in a DNA or RNA molecule in a virus.
A bacteriophage genus of the family LEVIVIRIDAE, whose viruses contain the short version of the genome and have a separate gene for cell lysis.
A family of membrane glycoproteins localized to TIGHT JUNCTIONS that contain two extracellular Ig-like domains, a single transmembrane segment, and a cytoplasmic tail of variable length.
Inorganic compounds that contain chlorine as an integral part of the molecule.
A family of enveloped, linear, double-stranded DNA viruses infecting a wide variety of animals. Subfamilies, based on biological characteristics, include: ALPHAHERPESVIRINAE; BETAHERPESVIRINAE; and GAMMAHERPESVIRINAE.
The suborder of aquatic CARNIVORA comprising the WALRUSES; FUR SEALS; SEA LIONS; and EARLESS SEALS. They have fusiform bodies with very short tails and are found on all sea coasts. The offspring are born on land.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Established cell cultures that have the potential to propagate indefinitely.
Immunoglobulins produced in response to VIRAL ANTIGENS.
Proteins that form the CAPSID of VIRUSES.
Ribonucleic acid that makes up the genetic material of viruses.
A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).
Virus diseases caused by the Lentivirus genus. They are multi-organ diseases characterized by long incubation periods and persistent infection.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
A genus of small, circular RNA viruses in the family ASTROVIRIDAE. They cause GASTROENTERITIS and are found in the stools of several vertebrates including humans. Transmission is by the fecal-oral route and there are at least eight human serotypes. The type species is Human astrovirus.
The relationships of groups of organisms as reflected by their genetic makeup.
Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)
It is used as an oxidizing and bleaching agent and as a disinfectant. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Proteins found in any species of virus.
Substances elaborated by viruses that have antigenic activity.
An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.

Neutralizing feature of commercially available feline calicivirus (FCV) vaccine immune sera against FCV field isolates. (1/88)

Four types of commercially available feline calicivirus (FCV) vaccine were compared in terms of their efficacy on the basis of the ability of the sera of specific-pathogen-free cats immunized by two injections of each type of vaccine to neutralize FCV field isolates. Each vaccine immune serum neutralized relatively well strains F4, F9, and 255, which were FCV laboratory strains. As to 36 strains of field isolates, however, vaccines A, B, C, and D immune sera did not neutralize 18-20 of the strains (50.0%-55.6%), 19-22 of the strains (52.8%-61.1%), 22-25 of the strains (61.1%-69.4%), and 8-16 of the strains (22.2%-44.4%), respectively. These results indicate that there is much difference in neutralizing antigenicity between the existing vaccine strains and the FCV strains that are prevalent in Japan, suggesting the need for improvement of FCV vaccines.  (+info)

Mapping of the feline calicivirus proteinase responsible for autocatalytic processing of the nonstructural polyprotein and identification of a stable proteinase-polymerase precursor protein. (2/88)

Expression of the region of the feline calicivirus (FCV) ORF1 encoded by nucleotides 3233 to 4054 in an in vitro rabbit reticulocyte system resulted in synthesis of an active proteinase that specifically processes the viral nonstructural polyprotein. Site-directed mutagenesis of the cysteine (Cys1193) residue in the putative active site of the proteinase abolished autocatalytic cleavage as well as cleavage of the viral capsid precursor, suggesting that this "3C-like" proteinase plays an important role in proteolytic processing during viral replication. Expression of the region encoding the C-terminal portion of the FCV ORF1 (amino acids 942 to 1761) in bacteria allowed direct N-terminal sequence analysis of the virus-specific polypeptides produced in this system. The results of these analyses indicate that the proteinase cleaves at amino acid residues E960-A961, E1071-S1072, E1345-T1346, and E1419-G1420; however, the cleavage efficiency is varied. The E1071-S1072 cleavage site defined the N terminus of a 692-amino-acid protein that contains sequences with similarity to the picornavirus 3C proteinase and 3D polymerase domains. Immunoprecipitation of radiolabeled proteins from FCV-infected feline kidney cells with serum raised against the FCV ORF1 C-terminal region showed that this "3CD-like" proteinase-polymerase precursor protein is apparently stable and accumulates in cells during infection.  (+info)

The capsid gene of feline calicivirus contains linear B-cell epitopes in both variable and conserved regions. (3/88)

In order to map linear B-cell (LBC) epitopes in the major capsid protein of feline calicivirus (FCV), an expression library containing random, short (100- to 200-bp) fragments of the FCV F9 capsid gene was constructed. Analysis of this library showed it to be representative of the region of the capsid gene that encodes the mature capsid protein. The library was screened by using polyclonal antisera from a cat that had been challenged experimentally with F9 to identify immunoreactive clones containing LBC epitopes. Twenty-six clones that reacted positively to feline antisera in immunoblots were identified. FCV-derived sequence from these clones mapped to a region of the capsid that spanned 126 amino acids and included variable regions C and E. An overlapping set of biotinylated peptides corresponding to this region was used to further map LBC epitopes by using F9 antisera. Four principal regions of reactivity were identified. Two fell within the hypervariable region at the 5' end of region E (amino acids [aa] 445 to 451 [antigenic site (ags) 2] and aa 451 to 457 [ags 3]). However, the other two were in conserved regions (aa 415 to 421 [ags 1; region D] and aa 475 to 479 [ags 4; central region E]). The reactivity of the peptide set with antisera from 11 other cats infected with a range of FCV isolates was also determined. Ten of 11 antisera reacted to conserved ags 4, suggesting that this region may be useful for future recombinant vaccine design.  (+info)

Analysis of the N-terminal polypeptide of the capsid precursor protein and the ORF3 product of feline calicivirus. (4/88)

The N-terminal unique polypeptide region of the capsid precursor protein of feline calicivirus (FCV) and the protein encoded by ORF3 of FCV were expressed as fusion proteins with glutathione S-transferase to analyze the expressed products in FCV-infected cells. Immunoblot analysis using a serum from a cat experimentally infected with FCV indicated relatively high immunogenicity of the N-terminal polypeptide in FCV-infected cats, as compared with the ORF3 protein. Specific antisera were prepared by immunization to mice with the fused proteins and used in immunoblot analysis. A 14 kD product corresponding to the N-terminal polypeptide and a 10 kD polypeptide of the ORF3 product were identified in the FCV-infected cells but not detected in the purified particles. No neutralization activity against FCV was detected in these antisera. The proteins identified as polypeptides of 14 kD and 10 kD in this study may have functions as non-structural proteins.  (+info)

Recovery and altered neutralization specificities of chimeric viruses containing capsid protein domain exchanges from antigenically distinct strains of feline calicivirus. (5/88)

Feline calicivirus (FCV) strains can show significant antigenic variation when tested for cross-reactivity with antisera produced against other FCV strains. Previous work has demonstrated the presence of hypervariable amino acid sequences in the capsid protein of FCV (designated regions C and E) that were postulated to constitute the major antigenic determinants of the virus. To examine the involvement of hypervariable sequences in determining the antigenic phenotype, the nucleotide sequences encoding the E regions from three antigenically distinct parental FCV strains (CFI, KCD, and NADC) were exchanged for the equivalent sequences in an FCV Urbana strain infectious cDNA clone. Two of the three constructs were recovered as viable, chimeric viruses. In six additional constructs, of which three were recovered as viable virus, the E region from the parental viruses was divided into left (N-terminal) and right (C-terminal) halves and engineered into the infectious clone. A final viable construct contained the C, D, and E regions of the NADC parental strain. Recovered chimeric viruses showed considerable antigenic variation from the parental viruses when tested against parental hyperimmune serum. No domain exchange was able to confer complete recognition by parental antiserum with the exception of the KCD E region exchange, which was neutralized at a near-homologous titer with KCD antiserum. These data demonstrate that it is possible to recover engineered chimeric FCV strains that possess altered antigenic characteristics. Furthermore, the E hypervariable region of the capsid protein appears to play a major role in the formation of the antigenic structure of the virion where conformational epitopes may be more important than linear in viral neutralization.  (+info)

Comparison of prevalence of feline herpesvirus type 1, calicivirus and parvovirus infections in domestic and leopard cats in Vietnam. (6/88)

A serosurvey of feline herpesvirus type 1 (FHV-1), feline calicivirus (FCV), and feline parvovirus (FPV) in cats from Ho Chi Minh City area in southern Vietnam was conducted in December 1998, and we compared the results with our previous results in northern Vietnam (Hanoi area). The positive rate of FHV and FCV in domestic cats were 44% and 74%, respectively. They were rather higher than those in Hanoi area, while the seropositivity of FPV (44%) was similar to that in Hanoi area. In leopard cats, the positive rate of FPV was high (3/4) and it indicated that FPV was prevailing in leopard cats in Vietnam.  (+info)

Identification and genomic mapping of the ORF3 and VPg proteins in feline calicivirus virions. (7/88)

Two minor proteins with molecular masses of 8.5 and 15.5 kDa were identified in feline calicivirus (FCV) virions. Direct sequence analysis showed that the N-terminal sequence of the 8.5-kDa protein was identical to that of the predicted protein encoded by open reading frame 3 (ORF3) of the FCV genome. The N-terminal sequence of the 15.5-kDa protein corresponded to amino acids 961-980 of the FCV ORF1 polyprotein and mapped to the genomic location of the calicivirus VPg. Antisera raised against recombinant ORF3 protein or the N-terminal 20 amino acids of the putative VPg reacted with the corresponding proteins present in both a Western blot analysis of purified FCV virions and an immunofluorescence assay of FCV-infected cells. A comparative analysis of radioactivity incorporated into virion proteins during in vivo labeling experiments indicated that the ORF3 protein is likely present in one or two copies per virion. The mobility of the ORF3 protein present in virions was similar to that of the ORF3 protein found in FCV-infected cells or expressed in bacteria. Direct N- and C-terminal sequence analysis of the purified ORF3 protein obtained by expression in bacteria demonstrated the presence of intact, uncleaved termini, suggesting that the observed difference between the calculated and the apparent masses in SDS-PAGE was not due to proteolytic processing of the protein.  (+info)

Proteinase-polymerase precursor as the active form of feline calicivirus RNA-dependent RNA polymerase. (8/88)

The objective of this study was to identify the active form of the feline calicivirus (FCV) RNA-dependent RNA polymerase (RdRP). Multiple active forms of the FCV RdRP were identified. The most active enzyme was the full-length proteinase-polymerase (Pro-Pol) precursor protein, corresponding to amino acids 1072 to 1763 of the FCV polyprotein encoded by open reading frame 1 of the genome. Deletion of 163 amino acids from the amino terminus of Pro-Pol (the Val-1235 amino terminus) caused a threefold reduction in polymerase activity. Deletion of an additional one (the Thr-1236 amino terminus) or two (the Ala-1237 amino terminus) amino acids produced derivatives that were 7- and 175-fold, respectively, less active than Pro-Pol. FCV proteinase-dependent processing of Pro-Pol in the interdomain region preceding Val-1235 was not observed in the presence of a catalytically active proteinase; however, processing within the polymerase domain was observed. Inactivation of proteinase activity by changing the catalytic cysteine-1193 to glycine permitted the production and purification of intact Pro-Pol. Biochemical analysis of Pro-Pol showed that this enzyme has properties expected of a replicative polymerase, suggesting that Pro-Pol is an active form of the FCV RdRP.  (+info)

PEREIRA, Joylson de Jesus et al. Molecular characterization of feline calicivirus variants from multicat household and public animal shelter in Rio de Janeiro, Brazil. Braz. J. Microbiol. [online]. 2018, vol.49, n.4, pp.777-784. ISSN 1517-8382. http://dx.doi.org/10.1016/j.bjm.2018.01.003.. The aim of this study was to perform the molecular characterization of conserved and variable regions of feline calicivirus capsid genome in order to investigate the molecular diversity of variants in Brazilian cat population. Twenty-six conjunctival samples from cats living in five public short-term animal shelters and three multicat life-long households were analyzed. Fifteen cats had conjunctivitis, three had oral ulceration, eight had respiratory signs (cough, sneeze and nasal discharge) and nine were asymptomatic. Feline calicivirus were isolated in CRFK cells and characterized by reverse transcription PCR target to both conserved and variable regions of open reading frame 2. The amplicons obtained were ...
Its efficacy in presence of maternally derived FCV antibodies. References. 1. Baulch-Brown, C., Love, D.N., Meanger, J., 1997. Feline calicivirus: a need for vaccine modification ? Aust. Vet. J. 75(3), 209-213.. 2. Baulch-Brown, C., Love, D.N., Meanger, J., 1999. Sequence variation within the capsid protein of Australian isolates of feline calicivirus. Vet. Microbiol. 68, 107-117.. 3. Binns, S.H., Dawson, S., Speakman, A.J., Cuevas, L.E., Hart, C.A., Gaskell, C.J., Morgan, K.L., Gaskell, R.M., 2000. A study of feline upper respiratory tract disease with reference to prevalence and risk factors for infection with feline calicivirus and feline herpesvirus. Journal of Feline Medicine and Surgery 2, 123-133.. 4. Chappuis, G., Stellmann, C., 1974. Etude sérologique des picornavirus félins: parenté-dominance des souches. Bull.Soc.Sci.Vet et Med comparée, 76(4), 289-299.. 5. Dawson, S., McArdle, F., Bennett, D., Carter, M., Bennett, M., Ryvar, R., Gaskell, R.M., 1993. Investigation of vaccine ...
Feline Calicivirus Vaccine shall be prepared from virus-bearing cell culture fluids. Only Master Seed Virus which has been established as pure, safe, and immunogenic shall be used for preparing the production seed virus for vaccine production. All serials of vaccine shall be prepared from the first through the fifth passage from the Master Seed Virus. (a) The Master Seed Virus shall meet the applicable general requirements prescribed in § 113.300. (b) The Master Seed Virus shall be tested for chlamydial agents as prescribed in § 113.43. (c) Each lot of Master Seed Virus used for vaccine production shall be tested for immunogenicity. The selected virus dose from the lot of Master Seed Virus shall be established as follows: (1) Thirty feline calicivirus susceptible cats shall be used as test animals (20 vaccinates and 10 controls). Throat swabs shall be collected from each cat and individually tested on susceptible cell cultures for the presence of feline calicivirus. Blood samples shall be ...
|strong|Mouse anti Feline Calicivirus antibody, clone S1-9|/strong| recognizes feline calicivirus and shows no cross-reactivity with FIV or FeLV.
Paws and Whiskers Cat Shelter has temporarily suspended adoptions and intakes of cats and kittens after persistent cases of Feline Calicivirus - commonly known as Calici. This viral infection is common in shelters and presents as an upper respiratory infection. While usually not life-threatening, this viral infection can spread in shelter and veterinary clinics. The closure is expected to last until December 16, 2017, or until the veterinarian gives clearance.. Cats that are unaffected will still be in the main shelter but it will close during this time to allow for any other cats that may have been exposed to show symptoms. Approximately one third of the shelters cats are affected.. Paws and Whiskers is taking veterinary recommended isolation protocols for cats displaying the symptoms - runny nose and eyes, tongue sores - by moving them to their facility next door. The affected cats will be isolated and treated for their symptoms, administered new vaccines, as well as strict cleaning ...
Feline Calicivirus小鼠单克隆抗体[FCV1-43](ab33990)经WB, ELISA, IHC实验严格验证。中国75%以上现货,所有产品均提供质保服务,可通过电话、电邮或微信获得本地专属技术支持。
Feline calicivirus (FCV) is a major causative agent of respiratory disease in cats. It is also one of the few cultivatable members of the family Caliciviridae. It has recently been reported that FCV binding is in part due to interaction with junction adhesion molecule-A. This report describes the characterization of additional receptor components for FCV. Chemical treatment of cells with sodium periodate showed that FCV recognized carbohydrate moieties on the surface of permissive cells. Enzymic treatment with Vibrio cholerae neuraminidase demonstrated that sialic acid was a major determinant of virus binding. Further characterization using linkage-specific lectins from Maackia amurensis and Sambucus nigra revealed that FCV recognized sialic acid with an α2,6 linkage. Using various proteases and metabolic inhibitors, it was shown that α2,6-linked sialic acid recognized by FCV is present on an N-linked glycoprotein.
The kinetics and biochemical properties of feline calicivirus (FCV) attachment to Crandell-Reese feline kidney cells were determined. Maximum binding was observed at pH 6.5. Cells in suspension at...
Antigen Background The Caliciviridae are a family of positive-stranded RNA viruses of unique morphology characterized by a series of cup-like depressions on the surface of the virus. Feline Calicivirus (FCV) is a ubiquitous pathogen of cats producing a variety of clinical symptoms, including oral ulceration, upper respiratory tract infection and polyarthritis. FCV has a genome of 7.7kb which encodes several proteins. Product Specific Information NCL-1G9 detects one of these, a capsid protein of 62 kD.. ...
Summary Isolates of feline calicivirus (FCV) can be divided into four groups according to plaque size under an agar overlay. All isolates classified as minute plaque, along with certain other isolates, are sensitive to inhibitors present in agar.
Science & Technology, Life Sciences & Biomedicine, Cell Biology, Medicine, Research & Experimental, Multidisciplinary Sciences, Research & Experimental Medicine, Science & Technology - Other Topics, feline calicivirus, caspase activation, capsid protein, DEATH ...
Feline Calicivirus Antibody (FCAVAb)-Dawnsail Biotech Co. Ltd.-Standard: 10 pieces/box Storage: cold storage 2-8℃ Time:10 min Sample: plasma
Feline Calicivirus radial colour 4M x mag (WY6SACGJV) by DavidBhella on Shapeways. Learn more before you buy, or discover other cool products in Sculptures.
Guest Post by Dr. Fern Crist. Virulent Systemic Feline Calicivirus - What Do We Really Know?. When Ingrid called me to tell me that Amber was making occasional odd gagging noises as if something was stuck in her throat, but that she seemed fine otherwise, I was certainly not expecting Amber to die within ten days.. Two days later, Ingrid told me Ambers appetite was decreased, and she was throwing up a little bit, gagging a little more but still seemed generally fine. My brain went on yellow alert, but not red. After all, Amber was still eating and keeping nearly all of it down. Her abdomen was not painful. Most such events resolve on their own, and since Amber gets very stressed with hospital visits, the benefits of getting her checked out had to be weighed against the stress of the hospital visit. It seemed wiser to just watch for a little longer.. But after a few more days of shes not worse but shes not better either, I hit my limit of lets keep an eye on it, so into the hospital we ...
Al-Molawi, N, Beardmore, VA, Carter, MJ, Kass, GEN and Roberts, LO (2003) Caspase-mediated cleavage of the feline calicivirus capsid protein ...
The two viruses commonly associated with cat flu or snuffles are the Feline Herpesvirus and the Feline Calicivirus. Both cause upper respiratory symptoms such as sneezing, coughing, conjunctivitis and discharge from the nose and eyes. The Herpesvirus tends to cause more severe symptoms. Ulcers on the tongue and chronic inflammation of the gums may also be seen with Calicivirus infection. Cats become infected by close contact with infected cats. Cats are at greatest risk of contracting snuffles at a boarding/breeding cattery or animal shelter. Recovered cats may continue to shed the virus without showing symptoms potentially infecting many animals.. ...
VS-FCV was first reported in the late 1990s and occurred as outbreaks at animal shelters and catteries. Fortunately, the virus does not seem to be spreading to the general cat population.. How Is Calicivirus Diagnosed and Treated?. Sophisticated testing of body fluids can be used to diagnose FCV infection, but most veterinarians make the diagnosis based on clinical signs. No medication can cure FCV. Treatment is mainly supportive and consists of administering fluids to combat dehydration, offering soft food until mouth ulcers heal, administering antibiotics to help treat secondary bacterial infections, and prescribing other medications as needed to help control other clinical signs. How Can Calicivirus Be Prevented? Several vaccines are available for preventing disease associated with FCV. There is also a vaccine against VS-FCV. All of the available FCV vaccines have been tested and found to be safe and effective when administered as directed.. The FCV vaccination is recommended for all cats. ...
What Is It? Cat Flu is also known as Feline Respiratory Disease, and much like the human cold it displays many of the same symptoms. It is caused by the Feline Calicivirus (FCV) or
To provide the best protection for your cat, we ask you to provide proof of their current F3 vaccination. This vaccination provides your cat with the best protection for the following: Feline Enteritis, Feline Rhinotracheitis and Feline Calicivirus. An F3 vaccination gives your cat maximum protection against Cat Flu and reduces likelihood of contraction, however does NOT prevent it entirely ...
Despite claims that GSE has antimicrobial effects,[11] there is no scientific evidence that GSE has such properties.[3][4] Some evidence indicates that the suspected antimicrobial activity of GSE was due to the contamination or adulteration of commercial GSE preparations with synthetic antimicrobials or preservatives.[1][2][12] These chemicals were not present in grapefruit seed extracts prepared in the laboratory, and GSE preparations without the contaminants were found to possess no detectable antimicrobial effect.[1] Although citrus seed extract is sold in health food markets,[12] there is no good evidence for any antimicrobial activity.[1] A study that examined possible antiviral properties of GSE found that it had no efficacy as a disinfectant for feline calicivirus and feline parvovirus.[13] ...
Ready to use lyophilised master mixes (8-well strips each) for detection of feline calicivirus, feline herpesvirus-1, Bordetella bronchiseptica, Chlamydophila felis, Mycoplasma felis and internal control. ...
Parvosol II RTU (ready-to-use) is a hospital grade quaternary ammonium formulation with even more effective disinfecting power, now ready-to-use from the bottle. Effective against Human Coronavirus, Parvovirus, Feline calicivirus, H1N1 (swine flu), Avian Influenza, and more.. Parvosol-II RTU has demonstrated effectiveness against viruses similar to SARS-CoV-2 on hard, non-porous surfaces. Therefore, Parvosol-II RTU can be used against SARS-CoV-2 when used in accordance with the directions for use against Canine Parvovirus on hard, non-porous surfaces.. Refer to the CDC website at: https://www.cdc.gov/coronavirus/2019-ncov/index.html for additional information.. ...
Table Top (EPA Reg # 1839-220-17268) has demonstrated effectiveness against viruses similar to 2019 novel coronavirus-Wuhan (also 2019-nCoV) on hard nonporous surfaces. Therefore, this product can be used against 2019 novel coronavirus-Wuhan (also 2019-nCoV) when used in accordance with the directions for use against Human Rotavirus, Feline Calicivirus, Canine Parvovirus, Rhinovirus Type 14, Rhinovirus Type 39 and Poliovirus Type 1 on hard, non-porous surfaces. Wipe surfaces often with Table Top to prevent spread of COVID- ...
Norwalk-like viruses (Feline Calicivirus), the Polio virus and even the common cold virus (Rhinovirus) are resistant to many surface disinfectants. But OPTIM 33 TB Surface Cleaner & Intermediate Level Disinfectant kills them all in one minute.. It also has a one minute claim against: Mycobacterium terrae, Human Coronavirus (SARS), HIV-1, Hepatitis B, Hepatitis C, Avian Influenza (Bird Flu), Salmonella, E.Coli, Pseudomonas, Staphylococcus aureus MRSA and other viruses & bacteria*, and can achieve a 99.999% broad-spectrum kill of vegetative bacteria in 30 seconds!. Click here for more about Sci Can Wipes. ...
Research in Virology and Veterinary Virology are based in new laboratories at three sites, the Ronald Ross Building, IC2 and Leahurst. They encompass studies of the pathogenicity, diagnostics, identification, epidemiology and immune responses to a range of viral pathogens including: Japanese encephalitis virus,HIV,respiratory syncytial virus, cytomegalovirus and other herpesviruses, chicken metapneumovirus, feline calicivirus and Schmallenberg virus. Techniques used include: diagnostic identification methods, flow cytometry, ELISA, epidemiology, PCR and transcriptomic and genomic technologies, including metagenomics, resequencing and genotyping cell separation, proteomics and infection models.. The aims of the research are to investigate the transmission routes and behaviour of pathogens during infections and use this knowledge to design better therapeutic strategies or vaccines in order to improve the health of humans and animals.. ...
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More... ...
A cat can not tell its pet owner when it feels in poor health, so the only solution to know is by proprietors will reveal an sickness in considered one of two ways. While it is difficult to induce long-time period immunity to bacterial infections, vaccines targeted toward viruses are normally more efficient at conferring long-time period immunity in the recipient. If the cat is spayed or neutered, chances are he or she was vaccinated as a kitten.. Dont vaccinate adult cats for FeLV - even if they have entry to the outdoors - since natural immunity to this disease is very sturdy by the point the cat is ~1 yr of age. We definitely should stop vaccinating with FVRCP every year but taking it one step additional, I dont observe the AAFP tips which counsel giving the FVRCP each 3 years because the risks outweigh the benefits ...
Not-so-quick catch-up, mostly Corys recent health history: the whole household has been in a lot of turmoil for the past three years or so. We moved to a new apartment a bit over 2 years ago, and the kids all seem to really prefer it - there all more confident and relaxed here. Trick has either lymphoma or IBS, both of which are treated the same way and a more clear diagnosis would be intrusive and expensive. Hes responding very well, has gained his weight back, and is no longer vomiting, so with any luck, hell be with us a long time yet, his same crazy self. Freya had a terrifying episode of her back end suddenly not working, but after a few days of pain meds and intense 24/7 nursing care, she got her functionality back just like nothing ever happened.. Cory, meanwhile, was originally diagnosed with calicivirus as the reason for his tongue to develop serious ulceration on the outer third or so, multiple times. It hasnt happened in years, and Im grateful for that! But he still has a very ...
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We report a disease outbreak in a Michigan rabbitry of a rabbit calicivirus distinct from the foreign animal disease agent, rabbit hemorrhagic disease virus (RHDV). The novel virus has been designated Michigan rabbit calicivirus (MRCV). Caliciviruses of the Lagovirus genus other than RHDV have not been described in US rabbit populations. The case-fatality rate was 32.5% (65/200). Clinical signs included hemorrhage and sudden death, with hepatic necrosis. Analysis of viral RNA sequence from >95% of the viral genome showed an average similarity of 79% with RHDV. Similarity of the predicted MRCV capsid amino acid sequence ranged from 89.8% to 91.3%, much lower than the 98% amino acid similarity between RHDV strains. Experimentally infected rabbits lacked clinical disease, but MRCV was detected in tissues by PCR. We propose that MRCV primarily causes subclinical infection but may induce overt RHD-like disease under certain field conditions.
Ned F. Kuehn, DVM, Diplomate, ACVIM. Feline respiratory disease complex includes those illnesses typified by rhinitis, conjunctivitis, lacrimation, salivation, and oral ulcerations. The principal diseases, Feline Viral Rhinotracheitis (FVR) and Feline Calicivirus (FCV) infections, affect exotic as well as ~domestic species. Feline Pneurnonitis (Chlamydia psittaci) and Mycoplasmal infections ,appear to be of lesser importance. Feline infectious peritonitis and pleuritis typically causes a more generalized condition but may cause signs of mild upper respiratory tract infection. I FVR and calliciviruses are host-specific and pose no known human risk. Human conjunctivitis caused by the feline chlamydial agent has been reported.. Etiology: Probably 40-45% of feline upper respiratory infections are caused by FVR s , which is a herpesvirus; incidence of FCV is similar. Dual infections with these viruses are common. Other organisms such as Chlamydia psittaci, Mycoplasma spp, and reoviruses are believed ...
The Iberian lynx (Lynx pardinus) is the most endangered felid species in the world. Lynx populations have decreased dramatically in size and distribution in the last four decades, thus becoming increasingly vulnerable to catastrophic events such as epizooties. From 1989 to 2000, serum samples were obtained from 48 free-ranging lynx captured in the Doñana National Park (DNP, n = 31) and mountains of Sierra Morena (SM, n = 17) in southern Spain. Samples were tested for antibodies against Toxoplasma gondii, feline herpesvirus 1 (FHV-1), feline calicivirus (FCV), feline/canine parvovirus (FPV/CPV), feline coronavirus, feline immunodeficiency virus (FIV), feline leukaemia virus and canine distemper virus (CDV) and for FeLV p27 antigen, to document baseline exposure levels. Antibodies against T. gondii were detected in 44% of lynx, with a significantly greater prevalence in DNP (61%) than in SM (12%). In DNP, prevalence was significantly higher in adult (81%) than in juvenile and sub-adult (41%) ...
DNA aptamers were developed against murine norovirus (MNV) using SELEX (Systematic Evolution of Ligands by EXponential enrichment). Nine rounds of SELEX led to the discovery of AG3, a promising aptamer with very high affinity for MNV as well as for lab-synthesized capsids of a common human norovirus (HuNoV) outbreak strain (GII.3). Using fluorescence anisotropy, AG3 was found to bind with MNV with affinity in the low picomolar range. The aptamer could cross-react with HuNoV though it was selected against MNV. As compared to a non-specific DNA control sequence, the norovirus-binding affinity of AG3 was about a million-fold higher. In further tests, the aptamer also showed nearly a million-fold higher affinity for the noroviruses than for the feline calicivirus (FCV), a virus similar in size and structure to noroviruses. AG3 was incorporated into a simple electrochemical sensor using a gold nanoparticle-modified screen-printed carbon electrode (GNPs-SPCE). The aptasensor could detect MNV with a ...
Calicivirin (EC 3.4.22.66, Camberwell virus processing peptidase, Chiba virus processing peptidase, Norwalk virus processing peptidase, Southampton virus processing peptidase, norovirus virus processing peptidase, calicivirus trypsin-like cysteine protease, calicivirus TCP, calicivirus 3C-like protease, calicivirus endopeptidase, rabbit hemorrhagic disease virus 3C endopeptidase) is an enzyme. This enzyme catalyses the following chemical reaction Endopeptidase with a preference for cleavage when the P1 position is occupied by Glu- and the P1- position is occupied by Gly- Viruses that are members of the Norovirus genus (Caliciviridae family) are a major cause of epidemic acute viral gastroenteritis. Meyers, G.; Rossi, C.; Thiel, H.J. (2004). Calicivirus endopeptidases. In Barrett, A.J.; Rawlings, N.D.; Woessner, J.F. Handbook of Proteolytic Enzymes (2nd ed.). London: Elsevier. pp. 1380-1382. Wirblich, C.; Sibilia, M.; Boniotti, M.B.; Rossi, C.; Thiel, H.J.; Meyers, G. (1995). 3C-like protease ...
Live vaccine containing per dose of 1 ml 105.2 TCID50 Feline viral rhinotracheitis virus; 104.7 pfu Feline calicivirus; 104.2 TCID50 Feline panleucopenia virus.
Norwalk-like viruses (Feline Calicivirus), the Polio virus and even the common cold virus (Rhinovirus) are resistant to many surface disinfectants. But OPTIM 33 TB Surface Cleaner & Intermediate Level Disinfectant kills them all in one minute. It also has a one minute claim against: Mycobacterium terrae, Human Coronavirus (SARS), HIV-1, Hepatitis B, Hepatitis C, Avian Influenza (Bird Flu), Salmonella, E.Coli, Pseudomonas, Staphylococcus aureus MRSA and other viruses & bacteria*, and can achieve a 99.999% broad-spectrum kill of vegetative bacteria in 30 seconds!. MSDS. Product Brochure. ...
Genetic characterization of a reptilian calicivirus (Cro1) : Vesiviruses in the family Caliciviridae infect a broad range of animal hosts including mammals, birds, fish, amphibians and reptiles. The vesivirus Cro1 strains were isolated from diseased snakes in the San Diego zoo in 1978 and reported as the first caliciviruses found in reptiles. The goal of this study was to characterize the Cro1 strain 780032I that was isolated in cell culture from a rock
Mycoplasma agassizii is one of the known causative agents of upper respiratory tract disease (URTD) in Mojave desert tortoises (Gopherus agassizii) and in gopher tortoises (Gopherus polyphemus). We sequenced the genomes ...
Rabbit Hemorrhagic Disease otherwise known as Viral Hemorrhagic Disease (VHD) of Rabbits or Rabbit Calicivirus Disease (RCD). Links and articles of interest to pet owners and veterinarians. ...
They additionally have been liberally infecting the species with the Rabbit Calicivirus Disease (RCD) from as far back as 1991 but since the animals have been able to develop immunities to it that has forced them into developing ever new strains of the killer. What thats (the rabbit eradication biological pipeline plan) trying to do is recognize that we have to put out new strains of the rabbit calicivirus at key points, to keep numbers low, rather than just waiting for numbers to bounce back, going into crisis mode and then trying to do what we can, Andreas Glanzig of the Invasive Animals Cooperative Research Centre (IACRC) at the University of Canberra told the ABC on November 25, 2015. (See Rabbit Control Plan Plays the Long Game to Contain Devastating Pest, Protect Threatened Species.) What the twenty-year plan is all about is making sure weve got new strains of calicivirus coming out every five to eight years, so that when the effectiveness of one strain starts to decrease weve got ...
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Principal Investigator:NAKATA Shuji, Project Period (FY):1995 - 1996, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:Pediatrics
The picornavirus genome consists of a single molecule of linear, postitive(+)-sense, single-strand RNA. It is non-segmented. The complete genome is 7000-8500 nucleotides long. At the 5-terminus of the genome has a long untranslated region 600-1200 bases in length, which is important in translation, virulence, and possibly encapsidation. There is a shorter untranslated region (50-100 bases in length) on the 3-terminus, which is important in (-)strand-synthesis. The 5-terminus untranslated region also has a clover leaf secondary structure known as the Internal Ribosome Entry Site (IRES), which distinguishes picornaviruses from other RNA viruses; this structure is important in translation and replication. The 5-terminus is modified by a covalently-attached VPg protein (which takes the place of a cap), while the 3-terminus is modified by polyadenylation. (sources: ICTVdB, Bedard, Flynn) ...
The picornavirus genome consists of a single molecule of linear, postitive(+)-sense, single-strand RNA. It is non-segmented. The complete genome is 7000-8500 nucleotides long. The 5-terminus of the genome has a long untranslated region 600-1200 bases in length, which is important in translation, virulence, and possibly encapsidation. There is a shorter untranslated region (50-100 bases in length) on the 3-terminus, which is important in (-)strand-synthesis. The 5-terminus untranslated region also has a clover leaf secondary structure known as the Internal Ribosome Entry Site (IRES), which distinguishes picornaviruses from other RNA viruses; this structure is important in translation and replication. The 5-terminus is modified by a covalently-attached VPg protein (which takes the place of a cap), while the 3-terminus is modified by polyadenylation. (sources: ICTVdB, Bedard, Flynn) ...
Feline viruses. Read about the symptoms, diagnosis, and treatment of different feline viruses including calicivirus, corona virus (FIP), leukemia, panleukopemia (FPV), and rhinotracheitis.
Rhinitis or sinusitis, sometimes called snuffles in laymens terms, is usually characterized by unilateral or bilateral, mucopurulent nasal discharge, sneezing, and congestion. A subtle sign of upper respiratory tract disease can be discharge matted on the paws or the medial aspect of the forelimbs. Discharge may collect here as the rabbit fastidiously cleans its face with its forepaws. In the early stages of disease, discharge may not be evident on the nose or even on the paws, however close examination of…. ...
The first calicivirus was described 75 years ago in California in a foot- and-mouth--like epidemic in swine. Control measures were slaughter and burial of all affected pigs. However, epidemic spread among swine continued for 24 years, then the disease disappeared. The virus was declared eradicated, but was re-discovered 16 years later in aborting marine mammals in the Pacific Basin Sixty-six years after discovery, the first human infections were published as a blistering disease of the hands, feet and face. This virus (genus Vesivirus) with large, diverse ocean reservoirs in fish, shellfish, seals and whales had become a human pathogen. Pathogenic vesiviruses can be associated with abortion, encephalitis, myocarditis, pancreatitis, blistering, hemorrhagic death and hepatitis among domestic animals, zoo-animals and marine mammals. Human involvement is less defined except for blistering and as we report here, hepatitis. Over 1000 sera collected from blood-donors, both normal and with suspected ...
The Toyota Mirai FCV has an EPA-estimated driving range of 502 km on a single fill of hydrogen, making it the distance champ of Zero Emission vehicles.
FCV - Formation Continue Vétérinaire. Looking for abbreviations of FCV? It is Formation Continue Vétérinaire. Formation Continue Vétérinaire listed as FCV
The first randomized controlled trial on FCV® has now been published, demonstrating that during laryngeal surgery Tritube improves visibility of the surgical site as compared with a MLT 6.0. Moreover, the group of Prof Schumann showed that FCV® improves lung.... ...

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