Calcium Phosphates: Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.Phosphates: Inorganic salts of phosphoric acid.Calcium Signaling: Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.Durapatite: The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.Bone Substitutes: Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapatite, beta-tricalcium phosphate, and various other biomaterials. The bone substitutes as inert materials can be incorporated into surrounding tissue or gradually replaced by original tissue.Apatites: A group of phosphate minerals that includes ten mineral species and has the general formula X5(YO4)3Z, where X is usually calcium or lead, Y is phosphorus or arsenic, and Z is chlorine, fluorine, or OH-. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Bone Cements: Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.Nanocomposites: Nanometer-scale composite structures composed of organic molecules intimately incorporated with inorganic molecules. (Glossary of Biotechnology and Nanobiotechology Terms, 4th ed)Calcium, Dietary: Calcium compounds used as food supplements or in food to supply the body with calcium. Dietary calcium is needed during growth for bone development and for maintenance of skeletal integrity later in life to prevent osteoporosis.Calcium Channels: Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.Calcium Carbonate: Carbonic acid calcium salt (CaCO3). An odorless, tasteless powder or crystal that occurs in nature. It is used therapeutically as a phosphate buffer in hemodialysis patients and as a calcium supplement.Calcium Oxalate: The calcium salt of oxalic acid, occurring in the urine as crystals and in certain calculi.Materials Testing: The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.Ceramics: Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed)Calcium Pyrophosphate: An inorganic pyrophosphate which affects calcium metabolism in mammals. Abnormalities in its metabolism occur in some human diseases, notably HYPOPHOSPHATASIA and pseudogout (CHONDROCALCINOSIS).Kidney Calculi: Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE.Calcification, Physiologic: Process by which organic tissue becomes hardened by the physiologic deposit of calcium salts.Tooth Remineralization: Therapeutic technique for replacement of minerals in partially decalcified teeth.Sugar PhosphatesBiocompatible Materials: Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.Glucose-6-Phosphate: An ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)Glyceraldehyde-3-Phosphate Dehydrogenases: Enzymes that catalyze the dehydrogenation of GLYCERALDEHYDE 3-PHOSPHATE. Several types of glyceraldehyde-3-phosphate-dehydrogenase exist including phosphorylating and non-phosphorylating varieties and ones that transfer hydrogen to NADP and ones that transfer hydrogen to NAD.Microscopy, Electron, Scanning: Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.Crystallization: The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Calcium Chloride: A salt used to replenish calcium levels, as an acid-producing diuretic, and as an antidote for magnesium poisoning.Phosphorus: A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.Hydroxyapatites: A group of compounds with the general formula M10(PO4)6(OH)2, where M is barium, strontium, or calcium. The compounds are the principal mineral in phosphorite deposits, biological tissue, human bones, and teeth. They are also used as an anticaking agent and polymer catalysts. (Grant & Hackh's Chemical Dictionary, 5th ed)Dental Cements: Substances used to bond COMPOSITE RESINS to DENTAL ENAMEL and DENTIN. These bonding or luting agents are used in restorative dentistry, ROOT CANAL THERAPY; PROSTHODONTICS; and ORTHODONTICS.Bone Regeneration: Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.Chemical Precipitation: The formation of a solid in a solution as a result of a chemical reaction or the aggregation of soluble substances into complexes large enough to fall out of solution.X-Ray Diffraction: The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Cariostatic Agents: Substances that inhibit or arrest DENTAL CARIES formation. (Boucher's Clinical Dental Terminology, 4th ed)Inositol Phosphates: Phosphoric acid esters of inositol. They include mono- and polyphosphoric acid esters, with the exception of inositol hexaphosphate which is PHYTIC ACID.Calcium Compounds: Inorganic compounds that contain calcium as an integral part of the molecule.Osteogenesis: The process of bone formation. Histogenesis of bone including ossification.Kinetics: The rate dynamics in chemical or physical systems.Calcium Isotopes: Stable calcium atoms that have the same atomic number as the element calcium, but differ in atomic weight. Ca-42-44, 46, and 48 are stable calcium isotopes.Amelogenin: A major dental enamel-forming protein found in mammals. In humans the protein is encoded by GENES found on both the X CHROMOSOME and the Y CHROMOSOME.Electron Probe Microanalysis: Identification and measurement of ELEMENTS and their location based on the fact that X-RAYS emitted by an element excited by an electron beam have a wavelength characteristic of that element and an intensity related to its concentration. It is performed with an electron microscope fitted with an x-ray spectrometer, in scanning or transmission mode.Dental Pulp Capping: Application of a protective agent to an exposed pulp (direct capping) or the remaining thin layer of dentin over a nearly exposed pulp (indirect capping) in order to allow the pulp to recover and maintain its normal vitality and function.Tissue Scaffolds: Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.Coated Materials, Biocompatible: Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.Microradiography: Production of a radiographic image of a small or very thin object on fine-grained photographic film under conditions which permit subsequent microscopic examination or enlargement of the radiograph at linear magnifications of up to several hundred and with a resolution approaching the resolving power of the photographic emulsion (about 1000 lines per millimeter).Minerals: Native, inorganic or fossilized organic substances having a definite chemical composition and formed by inorganic reactions. They may occur as individual crystals or may be disseminated in some other mineral or rock. (Grant & Hackh's Chemical Dictionary, 5th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Tooth Demineralization: A tooth's loss of minerals, such as calcium in hydroxyapatite from the tooth matrix, caused by acidic exposure. An example of the occurrence of demineralization is in the formation of dental caries.Spectroscopy, Fourier Transform Infrared: A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.Porosity: Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.Nanoparticles: Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.Calcinosis: Pathologic deposition of calcium salts in tissues.Dental Enamel: A hard thin translucent layer of calcified substance which envelops and protects the dentin of the crown of the tooth. It is the hardest substance in the body and is almost entirely composed of calcium salts. Under the microscope, it is composed of thin rods (enamel prisms) held together by cementing substance, and surrounded by an enamel sheath. (From Jablonski, Dictionary of Dentistry, 1992, p286)Surface Properties: Characteristics or attributes of the outer boundaries of objects, including molecules.Tissue Engineering: Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.Alkaline Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.Magnesium: A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.Bone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Glyceraldehyde 3-Phosphate: An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.Polymethacrylic Acids: Poly-2-methylpropenoic acids. Used in the manufacture of methacrylate resins and plastics in the form of pellets and granules, as absorbent for biological materials and as filters; also as biological membranes and as hydrogens. Synonyms: methylacrylate polymer; poly(methylacrylate); acrylic acid methyl ester polymer.Chitosan: Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.Silicates: The generic term for salts derived from silica or the silicic acids. They contain silicon, oxygen, and one or more metals, and may contain hydrogen. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th Ed)Calcium Channels, L-Type: Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.Saliva, Artificial: A solution used for irrigating the mouth in xerostomia and as a substitute for saliva.Osseointegration: The growth action of bone tissue as it assimilates surgically implanted devices or prostheses to be used as either replacement parts (e.g., hip) or as anchors (e.g., endosseous dental implants).Pliability: The quality or state of being able to be bent or creased repeatedly. (From Webster, 3d ed)Pentose Phosphate Pathway: An oxidative decarboxylation process that converts GLUCOSE-6-PHOSPHATE to D-ribose-5-phosphate via 6-phosphogluconate. The pentose product is used in the biosynthesis of NUCLEIC ACIDS. The generated energy is stored in the form of NADPH. This pathway is prominent in tissues which are active in the synthesis of FATTY ACIDS and STEROIDS.CitratesCalcium Fluoride: Calcium fluoride. Occurring in nature as the mineral fluorite or fluorspar. It is the primary source of fluorine and its compounds. Pure calcium fluoride is used as a catalyst in dehydration and dehydrogenation and is used to fluoridate drinking water. (From Merck Index, 11th ed)Glucosephosphate DehydrogenaseCalcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Calcium Gluconate: The calcium salt of gluconic acid. The compound has a variety of uses, including its use as a calcium replenisher in hypocalcemic states.Diphosphates: Inorganic salts of phosphoric acid that contain two phosphate groups.Biomimetic Materials: Materials fabricated by BIOMIMETICS techniques, i.e., based on natural processes found in biological systems.Methacrylates: Acrylic acids or acrylates which are substituted in the C-2 position with a methyl group.Calcium Sulfate: A calcium salt that is used for a variety of purposes including: building materials, as a desiccant, in dentistry as an impression material, cast, or die, and in medicine for immobilizing casts and as a tablet excipient. It exists in various forms and states of hydration. Plaster of Paris is a mixture of powdered and heat-treated gypsum.Compressive Strength: The maximum compression a material can withstand without failure. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p427)Electroplating: Coating with a metal or alloy by electrolysis.Magnesium Compounds: Inorganic compounds that contain magnesium as an integral part of the molecule.Dihydroxyacetone Phosphate: An important intermediate in lipid biosynthesis and in glycolysis.Phosphate Transport Proteins: Membrane proteins that are involved in the active transport of phosphate.Manufactured Materials: Substances and materials manufactured for use in various technologies and industries and for domestic use.Nephrolithiasis: Formation of stones in the KIDNEY.Dentin: The hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root, which is harder and denser than bone but softer than enamel, and is thus readily abraded when left unprotected. (From Jablonski, Dictionary of Dentistry, 1992)Time Factors: Elements of limited time intervals, contributing to particular results or situations.Calcium Radioisotopes: Unstable isotopes of calcium that decay or disintegrate emitting radiation. Ca atoms with atomic weights 39, 41, 45, 47, 49, and 50 are radioactive calcium isotopes.Microscopy, Electron, Transmission: Electron microscopy in which the ELECTRONS or their reaction products that pass down through the specimen are imaged below the plane of the specimen.Phosphorus, Dietary: Phosphorus used in foods or obtained from food. This element is a major intracellular component which plays an important role in many biochemical pathways relating to normal physiological functions. High concentrations of dietary phosphorus can cause nephrocalcinosis which is associated with impaired kidney function. Low concentrations of dietary phosphorus cause an increase in calcitriol in the blood and osteoporosis.Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).Zirconium: Zirconium. A rather rare metallic element, atomic number 40, atomic weight 91.22, symbol Zr. (From Dorland, 28th ed)Dentin, Secondary: Dentin formed by normal pulp after completion of root end formation.Carbonates: Salts or ions of the theoretical carbonic acid, containing the radical CO2(3-). Carbonates are readily decomposed by acids. The carbonates of the alkali metals are water-soluble; all others are insoluble. (From Grant & Hackh's Chemical Dictionary, 5th ed)Spectrometry, X-Ray Emission: The spectrometric analysis of fluorescent X-RAYS, i.e. X-rays emitted after bombarding matter with high energy particles such as PROTONS; ELECTRONS; or higher energy X-rays. Identification of ELEMENTS by this technique is based on the specific type of X-rays that are emitted which are characteristic of the specific elements in the material being analyzed. The characteristic X-rays are distinguished and/or quantified by either wavelength dispersive or energy dispersive methods.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Dental Materials: Materials used in the production of dental bases, restorations, impressions, prostheses, etc.Absorbable Implants: Implants constructed of materials designed to be absorbed by the body without producing an immune response. They are usually composed of plastics and are frequently used in orthopedics and orthodontics.Glass: Hard, amorphous, brittle, inorganic, usually transparent, polymerous silicate of basic oxides, usually potassium or sodium. It is used in the form of hard sheets, vessels, tubing, fibers, ceramics, beads, etc.Fluorides: Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices.Glucose-6-Phosphate Isomerase: An aldose-ketose isomerase that catalyzes the reversible interconversion of glucose 6-phosphate and fructose 6-phosphate. In prokaryotic and eukaryotic organisms it plays an essential role in glycolytic and gluconeogenic pathways. In mammalian systems the enzyme is found in the cytoplasm and as a secreted protein. This secreted form of glucose-6-phosphate isomerase has been referred to as autocrine motility factor or neuroleukin, and acts as a cytokine which binds to the AUTOCRINE MOTILITY FACTOR RECEPTOR. Deficiency of the enzyme in humans is an autosomal recessive trait, which results in CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA.Strontium: An element of the alkaline earth family of metals. It has the atomic symbol Sr, atomic number 38, and atomic weight 87.62.Calcium Hydroxide: A white powder prepared from lime that has many medical and industrial uses. It is in many dental formulations, especially for root canal filling.Particle Size: Relating to the size of solids.Tooth Calcification: The process whereby calcium salts are deposited in the dental enamel. The process is normal in the development of bones and teeth. (Boucher's Clinical Dental Terminology, 4th ed, p43)GlucosephosphatesComposite Resins: Synthetic resins, containing an inert filler, that are widely used in dentistry.Glycochenodeoxycholic Acid: A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.Umbilical Cord: The flexible rope-like structure that connects a developing FETUS to the PLACENTA in mammals. The cord contains blood vessels which carry oxygen and nutrients from the mother to the fetus and waste products away from the fetus.Caseins: A mixture of related phosphoproteins occurring in milk and cheese. The group is characterized as one of the most nutritive milk proteins, containing all of the common amino acids and rich in the essential ones.Sphingosine: An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)Osteoblasts: Bone-forming cells which secrete an EXTRACELLULAR MATRIX. HYDROXYAPATITE crystals are then deposited into the matrix to form bone.Biomimetics: An interdisciplinary field in materials science, ENGINEERING, and BIOLOGY, studying the use of biological principles for synthesis or fabrication of BIOMIMETIC MATERIALS.Adsorption: The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.DEAE-Dextran: Used as a support for ion-exchange chromatography.Urolithiasis: Formation of stones in any part of the URINARY TRACT, usually in the KIDNEY; URINARY BLADDER; or the URETER.Spectroscopy, Electron Energy-Loss: A technique for analysis of the chemical composition of molecules. A substance is bombarded with monochromatic ELECTRONS. Some of the electrons passing through the specimen will lose energy when they ionize inner shell electrons of the atoms in the specimen. The energy loss is element dependent. Analysis of the energy loss spectrum reveals the elemental composition of a specimen. ENERGY-FILTERED TRANSMISSION ELECTRON MICROSCOPY is a type of electron energy loss spectroscopy carried out in electron microscopes specially outfitted to analyze the spectrum of electron energy loss.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Titanium: A dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)Glycerophosphates: Any salt or ester of glycerophosphoric acid.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Phosphoric Acids: Inorganic derivatives of phosphoric acid (H3PO4). Note that organic derivatives of phosphoric acids are listed under ORGANOPHOSPHATES.Polyphosphates: Linear polymers in which orthophosphate residues are linked with energy-rich phosphoanhydride bonds. They are found in plants, animals, and microorganisms.Glycerol-3-Phosphate O-Acyltransferase: An enzyme that transfers acyl groups from acyl-CoA to glycerol-3-phosphate to form monoglyceride phosphates. It acts only with CoA derivatives of fatty acids of chain length above C-10. Also forms diglyceride phosphates. EC 2.3.1.15.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Lysophospholipids: Derivatives of PHOSPHATIDIC ACIDS that lack one of its fatty acyl chains due to its hydrolytic removal.Adenosine Triphosphate: An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.Silicate Cement: A relatively hard, translucent, restorative material used primarily in anterior teeth. (From Boucher's Clinical Dental Terminology, 4th ed, p50)PentosephosphatesPhotoelectron Spectroscopy: The study of the energy of electrons ejected from matter by the photoelectric effect, i.e., as a direct result of absorption of energy from electromagnetic radiation. As the energies of the electrons are characteristic of a specific element, the measurement of the energy of these electrons is a technique used to determine the chemical composition of surfaces.Parathyroid Hormone: A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.Egtazic Acid: A chelating agent relatively more specific for calcium and less toxic than EDETIC ACID.Carbamyl Phosphate: The monoanhydride of carbamic acid with PHOSPHORIC ACID. It is an important intermediate metabolite and is synthesized enzymatically by CARBAMYL-PHOSPHATE SYNTHASE (AMMONIA) and CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING).Oxalates: Derivatives of OXALIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that are derived from the ethanedioic acid structure.HexosephosphatesZinc Oxide-Eugenol Cement: Used as a dental cement this is mainly zinc oxide (with strengtheners and accelerators) and eugenol. (Boucher's Clinical Dental Terminology, 4th ed, p50)Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.Hexuronic Acids: Term used to designate tetrahydroxy aldehydic acids obtained by oxidation of hexose sugars, i.e. glucuronic acid, galacturonic acid, etc. Historically, the name hexuronic acid was originally given to ascorbic acid.Implants, Experimental: Artificial substitutes for body parts and materials inserted into organisms during experimental studies.Glucuronic Acid: A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.Cattle: Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.Hypercalciuria: Excretion of abnormally high level of CALCIUM in the URINE, greater than 4 mg/kg/day.Methylcellulose: Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.Phosphate-Binding Proteins: Proteins that bind to and are involved in the metabolism of phosphate ions.Calcium Channels, N-Type: CALCIUM CHANNELS that are concentrated in neural tissue. Omega toxins inhibit the actions of these channels by altering their voltage dependence.Dentin SensitivityAlginates: Salts of alginic acid that are extracted from marine kelp and used to make dental impressions and as absorbent material for surgical dressings.Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)Microscopy, Ultraviolet: Microscopy in which the image is formed by ultraviolet radiation and is displayed and recorded by means of photographic film.Solubility: The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Ions: An atom or group of atoms that have a positive or negative electric charge due to a gain (negative charge) or loss (positive charge) of one or more electrons. Atoms with a positive charge are known as CATIONS; those with a negative charge are ANIONS.Calcium Channel Agonists: Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture.Powders: Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)Phosphatidylinositol Phosphates: Phosphatidylinositols in which one or more alcohol group of the inositol has been substituted with a phosphate group.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Urinary Calculi: Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.Organophosphates: Carbon-containing phosphoric acid derivatives. Included under this heading are compounds that have CARBON atoms bound to one or more OXYGEN atoms of the P(=O)(O)3 structure. Note that several specific classes of endogenous phosphorus-containing compounds such as NUCLEOTIDES; PHOSPHOLIPIDS; and PHOSPHOPROTEINS are listed elsewhere.Subgingival Curettage: Removal of degenerated and necrotic epithelium and underlying connective tissue of a periodontal pocket in an effort to convert a chronic ulcerated wound to an acute surgical wound, thereby insuring wound healing and attachment or epithelial adhesion, and shrinkage of the marginal gingiva. The term is sometimes used in connection with smoothing of a root surface or ROOT PLANING. (Jablonski; Illustrated Dictionary of Dentistry, 1982)Calculi: An abnormal concretion occurring mostly in the urinary and biliary tracts, usually composed of mineral salts. Also called stones.Dental Cavity Lining: An inner coating, as of varnish or other protective substance, to cover the dental cavity wall. It is usually a resinous film-forming agent dissolved in a volatile solvent, or a suspension of calcium hydroxide in a solution of a synthetic resin. The lining seals the dentinal tubules and protects the pulp before a restoration is inserted. (Jablonski, Illustrated Dictionary of Dentistry, 1982)Acrylic ResinsRibosemonophosphates: Ribose substituted in the 1-, 3-, or 5-position by a phosphoric acid moiety.Dental Enamel Proteins: The proteins that are part of the dental enamel matrix.Temperature: The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.Hardness: The mechanical property of material that determines its resistance to force. HARDNESS TESTS measure this property.Lithiasis: A condition characterized by the formation of CALCULI and concretions in the hollow organs or ducts of the body. They occur most often in the gallbladder, kidney, and lower urinary tract.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Resin Cements: Dental cements composed either of polymethyl methacrylate or dimethacrylate, produced by mixing an acrylic monomer liquid with acrylic polymers and mineral fillers. The cement is insoluble in water and is thus resistant to fluids in the mouth, but is also irritating to the dental pulp. It is used chiefly as a luting agent for fabricated and temporary restorations. (Jablonski's Dictionary of Dentistry, 1992, p159)

Dietary calcium phosphate stimulates intestinal lactobacilli and decreases the severity of a salmonella infection in rats. (1/929)

We have shown recently that dietary calcium phosphate (CaPi) has a trophic effect on the intestinal microflora and strongly protects against salmonella infection. It was speculated that precipitation by CaPi of intestinal surfactants, such as bile acids and fatty acids, reduced the cytotoxicity of intestinal contents and favored growth of the microflora. Because lactobacilli may have antagonistic activity against pathogens, the main purpose of the present study was to examine whether this CaPi-induced protection coincides with a reinforcement of the endogenous lactobacilli. In vitro, Salmonella enteritidis appeared to be insensitive to bile acids and fatty acids, whereas Lactobacillus acidophilus was killed by physiologically relevant concentrations of these surfactants. Additionally, after adaptation to a purified diet differing only in CaPi concentration (20 and 180 mmol CaHPO4. 2H2O/kg), rats (n = 8) were orally infected with S. enteritidis. Besides reducing the cytotoxicity and the concentration of bile acids and fatty acids of ileal contents and fecal water, CaPi notably changed the composition of ileal bile acids in a less cell-damaging direction. Significantly greater numbers of ileal and fecal lactobacilli were detected in noninfected, CaPi-supplemented rats. As judged by the lower urinary NOx excretion, which is a biomarker of intestinal bacterial translocation, dietary CaPi reduced the invasion of salmonella. Additionally, the colonization resistance was improved considering the reduction of excreted fecal salmonella. In accordance, fewer viable salmonella were detected in ileal contents and on the ileal mucosa in the CaPi group. In conclusion, reducing the intestinal surfactant concentration by dietary CaPi strengthens the endogenous lactobacilli and increases the resistance to salmonella.  (+info)

Intracellular calcium responses to basic calcium phosphate crystals in fibroblasts. (2/929)

OBJECTIVE: To examine the intracellular calcium response to basic calcium phosphate (BCP) crystals in fibroblasts. DESIGN: In this study, intracellular calcium [Ca2+]i levels in fibroblasts were determined using the photoactive dye, fura-2. Interruption of these responses was accomplished by either removal of Ca2+ from the extracellular medium or addition of ammonium chloride that inhibits intracellular dissolution of BCP crystals by alkalinizing phagolysosomes. The effects of such interruptions on BCP induction expression of proto-oncogenes were demonstrated by the Northern blot analysis. RESULTS: Addition of media containing BCP crystals yielded an immediate 10-fold rise of [Ca2+]i over the baseline level in human fibroblasts. This peak was derived mostly from extracellular calcium and was not seen when BCP crystals in calcium-free media were added to fibroblasts. The [Ca2+]i concentration returned to the baseline level within 8 min. A second rise of [Ca2+]i started at 60 min and continued to increase up to at least 3 h. This peak was derived from intracellular dissolution of phagocytosed crystals and almost completely inhibited by 10 mM ammonium chloride. CONCLUSION: The initial transient [Ca2+]i increase probably serves as a second messenger leading to activation of early cellular responses such as c-fos expression which is important in BCP crystal-induced mitogenesis. The second, slower and more sustained rise of [Ca2+]i probably initiates other cellular processes needed for fibroblast mitogenesis.  (+info)

Calcium ions as efficient cofactor of polycation-mediated gene transfer. (3/929)

We investigated the effect of calcium on the transfection of non-viral DNA transfer systems. Cationic proteins such as the nuclear protein H1, the polycation polylysine and a number of commercial transfection agents exhibited high transfection rates in the presence of Ca2+. Without Ca2+ H1 and HMG1 were inactive in transfection of the human permanent endothelial cell line ECV 304 while cationic liposomes such as Lipofectin and Lipofectamine did not show any Ca2+ dependence. More detailed experiments showed that Ca2+ was replaceable by the lysosomotropic agent chloroquine. Furthermore, it was possible to separate the transfection-enhancing role of Ca2+ from the actual transfection process by adding Ca2+ to the cells after the transfection period and still to obtain a significant transgene expression. This makes it possible to distinguish between cellular uptake of H1 (or mediator)-DNA complexes and endocytotic release. We also replaced soluble Ca2+ by Ca-phosphate precipitates not containing DNA and obtained similar transfection results. This allowed us to suggest that the addition of free Ca2+ to the transfection medium resulted in nascent Ca-phosphate microprecipitates. The known fusogenic and membranolytic activity of such microprecipitates could facilitate the transport through and the release of the transfecting complexes from the endosomal/lysosomal compartment.  (+info)

Development of calcium phosphate cement for rapid crystallization to apatite. (4/929)

The purpose of this study was to develop an alpha-tricalcium phosphate (alpha-TCP) cement which transforms to hydroxyapatite (HAP) in a relatively short period. We used calcium and phosphate solutions as the liquid phase for the alpha-TCP cement. The alpha-TCP powder was first mixed with CaCl2 solution, and then mixed with NaH2PO4 or Na2HPO3 solution for a total powder/liquid ratio of 1.8. The setting time became shorter with the increase in the concentration of calcium and phosphate solutions, reaching 5 min, whereas the setting time was longer than 30 min when distilled water was used as the liquid phase. X-ray diffraction analysis revealed that the cement was mostly transformed to HAP within 24 h when kept in an incubator. We concluded that alpha-TCP should be mixed with calcium and phosphate solutions since this results in a moderate setting time and fast transformation to HAP even if the method of mixing becomes a little complex.  (+info)

Essential arterial hypertension and stone disease. (5/929)

BACKGROUND: Cross-sectional studies have shown that nephrolithiasis is more frequently found in hypertensive patients than in normotensive subjects, but the pathogenic link between hypertension and stone disease is still not clear. METHODS: Between 1984 and 1991, we studied the baseline stone risk profile, including supersaturation of lithogenic salts, in 132 patients with stable essential hypertension (diastolic blood pressure of more than 95 mm Hg) without stone disease and 135 normotensive subjects (diastolic blood pressure less than 85 mm Hg) without stone disease who were matched for age and sex (controls). Subsequently, both controls and hypertensives were followed up for at least five years to check on the eventual formation of kidney stones. RESULTS: Baseline urine levels in hypertensive males were different from that of normotensive males with regards to calcium (263 vs. 199 mg/day), magnesium (100 vs. 85 mg/day), uric acid (707 vs. 586 mg/day), and oxalate (34.8 vs. 26.5 mg/day). Moreover, the urine of hypertensive males was more supersaturated for calcium oxalate (8.9 vs. 6.1) and calcium phosphate (1.39 vs. 0.74). Baseline urine levels in hypertensive females were different from that of normotensive females with regards to calcium (212 vs. 154 mg/day), phosphorus (696 vs. 614 mg/day), and oxalate (26.2 vs. 21.7 mg/day), and the urine of hypertensive females was more supersaturated for calcium oxalate (7.1 vs. 4.8). These urinary alterations were only partially dependent on the greater body mass index in hypertensive patients. During the follow-up, 19 out of 132 hypertensive patients and 4 out of 135 normotensive patients had stone episodes (14.3 vs. 2.9%, chi-square 11.07, P = 0.001; odds ratio 5.5, 95% CI, 1.82 to 16.66). Of the 19 stone-former hypertensive patients, 12 formed calcium calculi, 5 formed uric acid calculi, and 2 formed nondetermined calculi. Of the urinary factors for lithogenous risk, those with the greatest predictive value were supersaturation of calcium oxalate for calcium calculi and uric acid supersaturation for uric acid calculi. CONCLUSIONS: A significant percentage of hypertensive subjects has a greater risk of renal stone formation, especially when hypertension is associated with excessive body weight. Higher oxaluria and calciuria as well as supersaturation of calcium oxalate and uric acid appear to be the most important factors. Excessive weight and consumption of salt and animal proteins may also play an important role.  (+info)

Clinical and biochemical correlates of starting "daily" hemodialysis. (6/929)

BACKGROUND: Daily hemodialysis has been proposed to improve outcomes for patients with end-stage renal disease. There has been increasing evidence that daily hemodialysis might have potential advantages over intermittent dialysis. However, despite these potential advantages, daily hemodialysis is infrequently used in the United States, and published accounts on the technique are few. METHODS: We describe patient outcomes after increasing their hemodialysis frequency from three to six times per week in a cohort of 72 patients treated at nine centers during 1972 to 1996. Analyses of predialysis blood pressure and laboratory parameters from 6 months before until 12 months after starting frequent hemodialysis used a repeated-measures statistical technique. RESULTS: Predialysis systolic and diastolic blood pressures fell by 7 and 4 mm Hg, respectively, after starting frequent hemodialysis (P = 0.02). Reductions were greatest among patients being treated with antihypertensive medications, despite a reduction in their dosage of medications. Postdialysis weight fell by 1.0% within one month of starting frequent hemodialysis and improved control of hypertension. After the initial drop, postdialysis weight increased at a rate of 0.85 kg per six months. Serum albumin rose by 0.29 g/dl (P < 0.001) between months 1 to 12 of treatment with daily hemodialysis. Hematocrit rose by 3.0 percentage points (P = 0.02) among patients (N = 56) not treated with erythropoietin during this period. Two years after the start of daily hemodialysis, Kaplan-Meier analyses showed a patient survival of 93%, a technique survival of 77%, and an arteriovenous fistula patency of 92%. Vascular access patency was excellent despite more frequent use of the access. CONCLUSIONS: These results suggest that in certain patients, daily hemodialysis might have advantages over three times per week hemodialysis.  (+info)

Method of transfection affects the cAMP-mediated induction of the RIIbeta subunit of protein kinase A in Sertoli cells: inhibition of response by increase in intracellullar calcium. (7/929)

mRNA for the regulatory subunit RIIbeta of cAMP-dependent protein kinase is stimulated more than 50-fold by cAMP in primary cultures of rat Sertoli cells. We have previously shown that this induction involves regulation of transcriptional activation as well as mRNA stabilization. The rat RIIbeta gene contains no cAMP response element (CRE), and the induction of RIIbeta mRNA is slow and requires on-going protein synthesis. When a construct containing the 5'-flanking region of the RIIbeta gene upstream of a CAT reporter was transfected into Sertoli cells by the calcium phosphate method, low and variable responses to cAMP (three- to fivefold) were observed, whereas a 15- to 20-fold increase in reporter activity by cAMP was observed after lipofectamine transfection. Interestingly, when a vector containing CRE elements upstream of a reporter gene was transfected into Sertoli cells, the responses to cAMP were similar regardless of the transfection method used. We have also demonstrated that increased intracellular levels of calcium by A23187 and thapsigargin dramatically inhibit cAMP-mediated induction of RIIbeta mRNA, but not the mRNA for the CRE-containing RIalpha gene. Furthermore, decreased cAMP responsiveness of endogenous RIIbetamRNA (but not RIalpha) was also observed in calcium phosphate-transfected Sertoli cells but not in lipofectamine-transfected cells. Thus, calcium-mediated reduction in cAMP response appears to be a gene-specific phenomenon.  (+info)

Implanted octacalcium phosphate (OCP) stimulates osteogenesis by osteoblastic cells and/or committed osteoprogenitors in rat calvarial periosteum. (8/929)

Our previous studies demonstrated that the octacalcium phosphate (OCP) causes new appositional bone formation on the OCP when implanted into the subperiosteal region of murine calvaria. The OCP may stimulate the cell population committed to the osteoblastic differentiation in the periosteum and have them express the phenotype. The present study was designed to investigate which periosteal cell population is involved in bone formation on the OCP with applying the OCP implants on top of and underneath the periosteum. The periosteum of the rat parietal bones was flapped and the OCP was implanted on top of or underneath the periosteum, in which the implantation sites were defined using the membrane filter. The histology was examined to see if new appositional bone formation occurs on the OCP implant under each condition. New bone was deposited on the OCP on the bone surface separated from the periosteum by the filter, whereas no bone was formed either under the periosteum separated from the bone surface by the filter or on the periosteum. The present study suggests that the OCP acts on osteoblasts, bone lining cells and/or their closely committed progenitors on the bone surface to express the phenotype and deposit new bone on the OCP implant.  (+info)

Basic Calcium Phosphate Crystals Induce Osteoarthritis-Associated Changes in Chondrocyte Phenotype through Activation of Calcium/Calmodulin Kinase ...
For subunit vaccines, adjuvants play a key role in shaping the magnitude, persistence and form of targeted antigen-specific immune response. Flagellin is a potent immune activator by bridging innate inflammatory responses and adaptive immunity and an adjuvant candidate for clinical application. Calcium phosphate nanoparticles are efficient carriers for different biomolecules like DNA, RNA, peptides and proteins. Flagellin-functionalized calcium phosphate nanoparticles were prepared and their immunostimulatory effect on the innate immune system, i.e. the cytokine production, was studied. They induced the production of the proinflammatory cytokines IL-8 (Caco-2 cells) and IL-1β (bone marrow-derived macrophages; BMDM) in vitro and IL-6 in vivo after intraperitoneal injection in mice. The immunostimulation was more pronounced than with free flagellin.
The kinetics of growth of calcium phosphates on synthetic hydroxyapatite (HAP), human enamel, whole dentin, and human calculus has been studied at 37 C at pH values from 4.97 to 5.10 held constant by the pH-stat addition of base. Following an initial induction period, dicalcium phosphate dihydrate (DCPD) crystallization takes place on the surface of these solids in all cases, even though the solutions are highly supersaturated with respect to HAP. The second order crystal growth kinetics are characteristic of the crystallization of DCPD on pure DCPD seed material. The ability of the substrate surfaces to nucleate DCPD falls in the order, synthetic HAP greater than enamel greater than calculus greater than dentin. Nucleation of DCPD, which is completed during the initial induction period, is very sensitive to small changes in pH, from 4.99 to 5.10.
Several studies demonstrated that the use of graft material has better clinical results for the treatment of intrabony defects. The purpose of this study is to compare the clinical and radiographic efficacy of alloplast (Biphasic calcium phosphate) and demineralized freeze-dried bone allograft (DFDBA) in treatment of periodontal intraosseous defects. A split mouth study was conducted in 20 subjects diagnosed with chronic periodontitis presenting atleast two intrabony defects in either arch. One quadrant (Site A) received alloplast (Biphasic calcium phosphate) and the contralateral defect (Site B) received DFDBA. The results of study showed that clinically Site B (DFDBA) showed greater reduction in pocket depth and gain in clinical attachment level than site A (Biphasic calcium phosphate), however it was not statistically significant. Site A (Biphasic calcium phosphate) showed slightly more gingival marginal recession than Site B (DFDBA). Radiographically Site B (DFDBA) showed greater bone fill ...
Nacre-like structures have attracted great interest in recent years due to their outstanding toughness, stiffness and impact resistance. However, there is a challenge associated with engineering nacre-like calcium phosphate crystals. In this study, thin nacreous-like monetite sheets were synthesized in solutions guided by a surfactant. The influence of temperature, initial pH, Ca/P ratio, stirring time and the concentration of cetyltrimethylammonium bromide (CTAB) on the nacre-like structure has been studied. Findings showed that a nacre-like structure could only be formed at a high temperature (90 °C), high initial pH (11), sufficient stirring time (3 h), and under the presence of CTAB. A small-angle X-ray scattering experiment carried out at a synchrotron radiation facility showed that the distance between nanolayers was around 2.6 nm and TEM confirmed the fine sheet-like structure. The mechanism of the formation the nacre-like structure and its characterization were discussed.. ...
Page contains details about Texas Red-labeled DiI-loaded lipid-coated calcium phosphate nanoparticles . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
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Tetracalcium phosphate is the compound Ca4(PO4)2O, (4CaO.P2O5). It is the most basic of the calcium phosphates, and has a Ca/P ratio of 2, making it the most phosphorus poor phosphate. It is found as the mineral hilgenstockite, which is formed in industrial phosphate rich slag (called "Thomas slag"). This slag was used as a fertiliser due to the higher solubility of tetracalcium phosphate relative to apatite minerals. Tetracalcium phosphate is a component in some calcium phosphate cements that have medical applications. Tetracalcium phosphate cannot be prepared in aqueous solution, any precipitates having the correct Ca/P ratio contain hydroxide ions in apatitic phases. Solid state reactions are used, one example is: 2CaHPO4 + 2CaCO3 → Ca4(PO4)2O + CO2 +H2O (1450-1500 °C for up to 12 hours) As tetracalcium phosphate is metastable the molten reaction mixture has to be quenched to rapidly, reduce the temperature and prevent the formation of other compounds such as Ca3(PO4)2, CaO, CaCO3 and ...
Porous calcium phosphate implant compositions that approximate the chemical composition of natural bone mineral are provided. In addition to calcium phosphate, the compositions include an effervescent agent to promote the formation of interconnected pores and a cohesiveness agent to maintain the shape and hardness of the hardened composition. When introduced at an implant site, the calcium phosphate compositions are remodeled into bone. Methods for using the calcium phosphate compositions, e.g., to repair or replace bone, are also provided.
A calcium phosphate cement suitable for use in dental and bone prosthesis is disclosed, which include calcium phosphate particles having a diameter of 0.05 to 100 microns, wherein said calcium phosphate particles on their surfaces have whiskers or fine crystals having a width ranging from 1 to 100 nm and a length ranging from 1 to 1000 nm.
Transfection of DNA into cells is an indispensible protocol in molecular biology. While plenty of lipid-based transfection reagents are commercially available nowadays, a quick, simple, efficient and inexpensive method is to transfect eukaryotic cells via calcium phosphate co-precipitation with DNA (Graham and van der Eb, 1973). The insoluble calcium phosphate precipitate with the attached DNA adheres to the cell surface and is brought into the cells by endocytosis. Calcium phosphate transfection has been optimized and widely used with many adherent and nonadherent cell lines (Jordan et al., 1996). Calcium phosphate transfection can result in transient expression of the delivered DNA in the target cell, or establishment of stable cell lines (the latter requires a drug selection process). This protocol is also widely used for co-expression of plasmids for packaging viruses. Efficiency of transfection can be close to 100% depending on the cell lines used. Here, a calcium phosphate transfection protocol is
TY - JOUR. T1 - Late-term healing in an augmented sinus with different ratios of biphasic calcium phosphate. T2 - A pilot study using a rabbit sinus model. AU - Lim, Hyun Chang. AU - Hong, Ji Youn. AU - Lee, Jung Seok. AU - Jung, Ui Won. AU - Choi, Seong Ho. PY - 2016/1/1. Y1 - 2016/1/1. N2 - Purpose: The aim of this pilot study was to determine the osteoconductivity and dimensional stability of augmented sinuses using different ratios of biphasic calcium phosphate (BCP) in a rabbit sinus model. Methods: Each sinus of New Zealand white rabbits (2.5-3.5 kg) was assigned to one of two groups: BCP with a hydroxyapatite to β-tricalcium phosphate (HA:β-TCP) ratio of 70:30 (group TCP30) and BCP with an HA:β-TCP ratio of 30:70 (group TCP70). After preparing a window in the antral wall of a sinus, the Schneiderian membrane was elevated, and the applicable material was grafted. A fluorochrome calcein green was injected five days before euthanizing the animals at four months post-surgery. The specimens ...
Powders composed of four morphologically different calcium phosphate particles were prepared by precipitation from aqueous solutions: flaky, brick-like, elongated orthogonal, and spherical. The particles were then loaded with either clindamycin phosphate as the antibiotic of choice, or fluorescein, a model molecule used to assess the drug release properties. A comparison was carried out of the comparative effect of such antibiotic-releasing materials on: sustained drug release profiles; Staphylococcus aureus growth inhibition; and osteogenic propensities in vitro. Raman spectroscopic analysis indicated the presence of various calcium phosphate phases, including monetite (flaky and elongated orthogonal particles), octacalcium phosphate (brick-shaped particles) and hydroxyapatite (spherical particles). Testing the antibiotic-loaded calcium phosphate powders for bacterial growth inhibition demonstrated satisfying antibacterial properties both in broths and on agar plates. All four calcium-phosphate
The gold standard for bone replacement today, autologous bone, suffers from several disadvantages, such as the increased risk of infection due to the need for two surgeries. Degradable synthetic materials with properties similar to bone, such as calcium phosphate cements, are a promising alternative. Calcium phosphate cements are suited for a limited amount of applications and improving their physical properties could extend their use into areas previously not considered possible. For example, cement with increased strength could be used as load bearing support in selected applications. The focus of this thesis is, therefore, on how the physical properties of acidic calcium phosphate cements (brushite cements) are affected by compositional variations, with the ultimate aim of making it possible to formulate brushite cements with desired properties.. In this thesis a method to measure the porosity of a cement was developed. This method is advantageous over existing methods as it is easy to use, ...
The gold standard for bone replacement today, autologous bone, suffers from several disadvantages, such as the increased risk of infection due to the need for two surgeries. Degradable synthetic materials with properties similar to bone, such as calcium phosphate cements, are a promising alternative. Calcium phosphate cements are suited for a limited amount of applications and improving their physical properties could extend their use into areas previously not considered possible. For example, cement with increased strength could be used as load bearing support in selected applications. The focus of this thesis is, therefore, on how the physical properties of acidic calcium phosphate cements (brushite cements) are affected by compositional variations, with the ultimate aim of making it possible to formulate brushite cements with desired properties.. In this thesis a method to measure the porosity of a cement was developed. This method is advantageous over existing methods as it is easy to use, ...
In early 1980s, researchers discovered self-setting calcium orthophosphate cements, which are bioactive and biodegradable grafting bioceramics in the form of a powder and a liquid. After mixing, both phases form pastes, which set and harden forming either a non-stoichiometric calcium deficient hydroxyapatite or brushite. Since both of them are remarkably biocompartible, bioresorbable and osteoconductive, self-setting calcium orthophosphate formulations appear to be promising bioceramics for bone grafting. Furthermore, such formulations possess excellent molding capabilities, easy manipulation and nearly perfect adaptation to the complex shapes of bone defects, followed by gradual bioresorption and new bone formation. In addition, reinforced formulations have been introduced, which might be described as calcium orthophosphate concretes. The discovery of self-setting properties opened up a new era in the medical application of calcium orthophosphates and many commercial trademarks have been introduced as
A calcium phosphate cement suitable for use in dental and bone prosthesis is disclosed, which include calcium phosphate particles having a diameter of 0.05 to 100 microns, wherein said calcium phosphate particles on their surfaces have whiskers or fine crystals having a width ranging from 1 to 100 nm and a length ranging from 1 to 1000 nm.
A polymer scaffold is provided comprising an extensively interconnected macroporous network. The polymer scaffold embodies macropores having a diameter in a range of 0.5-3.5 mm, and preferably in a range of about 1.0-2.0 mm. The polymer scaffold is prepared using a novel process which advantageously combines the techniques of particulate leaching and phase inversion to render a process that provides amplified means by which to control the morphology of the resulting polymer scaffold. The polymer scaffold has utility in the area of tissue engineering, particularly as a scaffold for both in vitro and in vivo cell growth. The polymer scaffold may be produced using pure polymer or alternatively a composite material may be formed consisting of a macroporous polymer scaffold and osteoclast-resorbable calcium phosphate particles with a binding agent binding the calcium phosphate particles to the polymer scaffold.
The anatomical grading parameter angulation (valgus/varus) (abnormal outward/inward turning of the knee) was assessed the following way: AP and lateral radiographs were taken for the fractured and healthy tibia plateau at Baseline, right after surgery and all follow-up timepoints. Additional oblique radiographs at 45° or other fracture imaging was optional. All post-operative radiographs were compared against the healthy tibia films post-surgery and all follow-up radiographs were compared with the post-operative radiographs to evaluate the quality and changes in reduction at each timepoint. CT scans were only mandatory at Baseline ...
Nanostructured calcium phosphate and biphasic calcium phosphates have been studied and stand out as biomaterials for bone regeneration This is due to the fact that Get Price ...
alpha-tricalcium phosphate: unit cells is 312 atoms compared with 273 for beta-tricalcium phosphate; see also records for beta-tricalcium phosphate, tricalcium phosphate
Introduction: Dicalcium phosphate dihydrate (DCPD) is a member of the family of calcium phosphates (CP), which has many uses in bone cement. Recently, graphene and its derivatives have been studied to increase the biological and mechanical properties of CP structures and their results have been satisfactory. Objective: In this study, the main objective is to investigate the physical properties of GO/DCPD powders, which has been synthesized via a simple precipitation method. Material and Methods: Calcium nitrate tetrahydrate and diammonium hydrogen phosphate were used as a precursor for DCPD synthesis. DCPD was precipitated in the presence of graphene oxide. The powders obtained after washing and drying were evaluated. The analysis performed in the sample includes inductively coupled plasma (ICP), Raman Spectroscopy, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction, Energy dispersive X-ray spectroscopy (EDS), X-ray photoelectron spectroscopy, Field Emission Scanning Electron Microscope
F1044 - 05(2011)e1 Standard Test Method for Shear Testing of Calcium Phosphate Coatings and Metallic Coatings , ceramic materials, hydroxylapatite, shear testing, tribasic calcium phosphate, Bonding, Nonporous coatings, Porosity--medical/surgical materials, Ring shear test, Shear testing--medical materials/applications, Substrates--surgical implant applications, Testing methods--surgical implants, Tribasic calcium phosphate, Adhesive bonds, Calcium phosphate coatings, Coatings (surgical implants), Hydroxylapatite (HA), Metallic coatings,
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Sintering Behavior and Mechanical Properties of Magnesium/β-Tricalcium Phosphate Composites Sintered by Spark Plasma SinteringSintering Behavior and Mechanical Properties of Magnesium/β-Tricalcium Phosphate Composites Sintered by Spark Plasma Sintering ...
The particularities of cesium incorporation into synthetic calcium phosphates with either apatite or whitlockite-type structures were investigated using the sorption process from aqueous solution and further heating to 700 °C. The nanoparticles for sorption were prepared by wet precipitation from aqueous solutions at a fixed molar ratio of Ca/P = 1.67 and two different ratios of CO32−/PO43− (0 or 1). The obtained substituted calcium phosphates and corresponding samples after the sorption of cesium from solutions with different molar concentrations (c(Cs+) = 0.05, 0.1 and 0.25 mol L−1) were characterized by powder X-ray diffraction, FTIR spectroscopy, scanning electron microscopy and elemental analysis. Based on the combination of X-ray diffraction and elemental analyses data for the powders after sorption, the cesium incorporated in the apatite- or whitlockite-type structures and its amount increased with its concentration in the initial solution. For sodium-containing calcium phosphate even
Here is the abstract of our proposed work:. Elevated levels of oxalate as well as urinary tract infections have independently been associated with subsets of idiopathic stone formers. However, precise mechanisms by which moderately elevated levels of oxalate and or renal tubular infections promote kidney stone formation are not understood. In addition interplay between moderately elevated oxalate and urinary tract infections in driving stone disease has not ever been studies. Idiopathic stone formers often present with mixed type stones. The stones contain calcium oxalate as well as calcium phosphate deposits. There is a large body of literature that supports the notion of presence of Randalls plaques (sub-epithelial Calcium Phosphate precipitates) associated with deposits of Calcium oxalate. While tubular precipitation of calcium oxalate as well as calcium phosphate can be explained by urinary precipitations as a result of elevated levels of calcium, phosphate and /or oxalate, the exact ...
Calcium phosphate cements (CPC) are well-established bone replacement materials that have been used in dentistry and orthopedics for more than 25 years. The monitoring of bone cements and the associated healing processes in the human body is difficult and so far has often been achieved using cytotoxic X-ray contrast agent additives. These additives have a negative effect on the mechanical properties and setting time of the bone cement. In this paper, we present a novel approach to prepare contrastive CPC by the incorporation of luminescent Eu3+-doped hydroxyapatite (Eu:HAp) nanoparticles. Eu-doped CPC (Eu:CPC) exhibited enhanced mechanical properties compared to pure CPC. Furthermore, the red photoluminescence of Eu:CPC may allow the observation of CPC-related healing processes without the use of harmful ionizing radiation.
DOI: 10.11607/jomi.4020 Purpose: The aim of this study was to determine the effect of collagenated biphasic calcium phosphate (CBCP) loaded with fibroblast growth factor-2 (FGF-2) on bone regeneration in a rabbit sinus model. Materials and Methods: Bilateral sinus augmentations were performed using either FGF-2 loaded CBCP (FGF-2 group) or CBCP only (control group) in 10 rabbits. The experimental animals were euthanized at 2 weeks (n = 5) or 4 weeks (n = 5) postoperatively. Volumetric analyses were done by means of microcomputed tomography and histomorphometry. Results: The volumes of total augmentation, new bone, residual material, and fibrovascular tissue were significantly greater in the FGF-2 group than in the control group at 2 weeks, but the differences between the two groups had disappeared by 4 weeks. Histologically, the healing patterns, such as new bone formation and the resorption of residual material, did not differ notably between the two groups. The results of the histometric ...
DOI: 10.5176/2382-5685_VETSCI16.17 Authors: Richa Jha, Shantanu Tamuly, Mumtesh Kumar Saxena Abstract: Adjuvant play important role in enhancing the i
TY - JOUR. T1 - Reaction of bone to tricalcium phosphate ceramic pellets. AU - Cutright, Duane E.. AU - Bhaskar, Surindar N.. AU - Brady, John M.. AU - Getter, Lee. AU - Posey, William R.. PY - 1972/1/1. Y1 - 1972/1/1. N2 - This study indicates that tricalcium phosphate is well accepted by the tissue and may actually contribute mineral salts for the formation of bone at the site as the ceramic is broken down into granules.. AB - This study indicates that tricalcium phosphate is well accepted by the tissue and may actually contribute mineral salts for the formation of bone at the site as the ceramic is broken down into granules.. UR - http://www.scopus.com/inward/record.url?scp=0015337449&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0015337449&partnerID=8YFLogxK. U2 - 10.1016/0030-4220(72)90457-4. DO - 10.1016/0030-4220(72)90457-4. M3 - Article. C2 - 4502161. AN - SCOPUS:0015337449. VL - 33. SP - 850. EP - 856. JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral ...
In principle, bone has a good self-healing capacity. However, for defects larger than a certain size ("critical size defect") spontaneous healing of bone injury is not possible. Such defects can occur in many diseases such as osteoarthritis, bone cysts and tumors, or as a result of surgical procedures, for instance osteolyses associated with loosened endoprostheses or osteotomies. The gold standard for the treatment of bone defects is an autologous bone transplantation; however, disadvantages of the method include follow-up operations that are necessary in addition to the bone harvesting from the iliac crest, which are connected with significant comorbidity.1 Availability of natural bone is restricted and often not sufficient to heal large bone defects, while maintenance of an extensive bone bank is expensive and complicated by long-term tissue preservation issues. To overcome these difficulties, a number of synthetic and partial synthetic bone substitute materials have been developed. In ...
Jun 29, 2005· Re: Di-calcium phosphate. I just bought some minerals with dicalcium phosphate for livestock over the weekend that I plan to try in my mineral site. Had I think 20 percent dicalcium phosphate, also picked up a bag of loose trace minerals with salt. The 50 lb bag at rural king was like $6 for the dicalcium phosphate and $5 for the other minerals ...
Polymer modified calcium phosphate cements made with cement powders of varying tetracalcium phosphate [TTC P] content were prepared using two different molecular weight fractions of poly(acrylic acid)
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Calcium phosphate cements are used in medicine to fill bone defects or give support to screws and plates in fracture fixation. The cements are formed via mixing a powder with water and the mixture harden through a dissolution-precipitation reaction. Today the cement mixing is performed in the operating room and consists of several complicated steps that need to be performed under sterile conditions. This renders the mixing a risk factor, potentially leading to harm for the patient e.g. unsatisfactory healing or infection. To reduce this risk, premixed cements have been developed using glycerol as mixing liquid. The premixed cement sets when it is exposed to body liquids. Therefore, premixed cement can be delivered to the operating room in prefilled syringes ready for use, thus eliminating the mixing step.. The aim of this thesis is to describe differences between premixed and water-mixed cements and their advantages and drawbacks. The differences will be discussed based on results obtained from ...
Functions: Emulsifier, Humectant, Sequestrant, Stabilizer, Thickener. Calcium phosphate is a family of materials and minerals containing calcium ions -Ca2+- together with inorganic phosphate anions. Some so-called calcium phosphates contain oxide and hydroxide as well. They are white solids of nutritious value. - Wikipedia. Names: Phosphate de calcium dhydrogène, Phosphate de calcium dihydrogène, Phosphates de calcium, Orthophosphates de calcium, Orthophosphate monocalcique, phosphate monocalcique, Orthophosphate dicalcique, Orthophosphate tricalcique, Phosphate tricalcique, Phosphate de calcium monobasique, Phosphate de calcium dibasique, Phosphate de calcium tribasique, Phosphate de calcium (i), Phosphate de calcium (ii), Phosphate de calcium (iii), calcium (phosphate), phosphate de calcium. ...
Hydroxapatite (HA) is a stable phase with low dissolution rate in body fluid. Meanwhile, β-tricalcium phosphate (β-TCP) is rather soluble but the dissolution rate is too fast for bone bonding. Therefore a mixture of both is desirable to control the bioresorbability. In this work, calcium phosphate powder has been synthesized via sol gel and wet precipitation method to compare phase behaviour of these powders upon calcination. XRD result clearly revealed that both as-synthesized powders were pure HA with good purity. The decomposition of HA to TCP took place in the range of 700-800 °C and 800-900 °C for sol gel and wet chemical precipitation powder, respectively. The weight loss detected at 700-850°C in TGA analysis confirmed the presence of this biphasic mixtures. From FTIR analysis, profound change in OH- band intensity was attributed to the increased in HA crystallinity with calcination temperature.. ...
Bone, tooth enamel, and dentin accumulate Sr 2+ , a natural trace element in the human body. Sr 2+ comes from dietary and environmental sources and is thought to play a key role in osteoporosis treatments. However, the underlying impacts of Sr 2+ on bone mineralization remain unclear and the use of synthetic apatites (which are structurally different from bone mineral) and non-physiological conditions have led to contradictory results. Here, we report on the formation of a new Sr 2+-rich and stable amorphous calcium phosphate phase, Sr(ACP). Relying on a bioinspired pathway, a series of Sr 2+ substituted hydroxya-patite (HA) that combines the major bone mineral features is depicted as model to investigate how this phase forms and Sr 2+ affects bone. In addition, by means of a comprehensive investigation the biominer-alization pathway of Sr 2+ bearing HA is described showing that not more than 10 at% of Sr 2+ , i.e. a physiological limit incorporated in bone, can be incorporated into HA without phase
High-Performance Ceramics IV: Physicochemical and Mechanical Properties of Composite of Chitosan Microspheres/Calcium Phosphate Cement
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Materials that augment bone cell proliferation and osteogenic activity have important therapeutic implications for bone regeneration and for use in skeletal reconstruction and joint replacement. We have studied the growth and interactions of human bone marrow cells on a variety of new cement composites in vitro. These cement materials are composed of calcium-deficient hydroxyapatites, carbonated apatite and amorphous calcium phosphate. Cell proliferation was significantly reduced and cell differentiation increased in the presence of these cements compared with cells cultured on tissue culture plastic. Alkaline phosphatase, one of the markers of the osteoblast phenotype, was dramatically stimulated by 3 of the 4 cements examined between day 4 and day 10, above levels observed following culture of human osteoblasts on plastic alone. Photomicroscopic examination demonstrated growth and close integration of bone marrow cells and 3 of the composites. Longer term marrow cultures (15 day) on the cements
Alfa Aesar™ Calcium phosphate (pyro), 96% min 250g Alfa Aesar™ Calcium phosphate (pyro), 96% min Inorganic Calcium Compounds
Optimization for stoichiometric and morphology-controlled calcium phosphate crystals from bio-bearing calcium phosphate (BCP) under hydrothermal conditions ...
A high purity α-tricalcium phosphate ceramic having a superior biocompatibility for use mainly as a bone filler, is produced by shaping a powder material formed by a wet method, followed by sintering it and then cooling at a predetermined rate.
Authors: Hesaraki, Saeed , Sharifi, Davood Article Type: Research Article Abstract: Calcium phosphate cements (CPCs) are biocompatible and osteoconductive materials used in dental, craniofacial and orthopaedic applications. One of the most important advantages of these materials is their replacement with bone followed by resorption. Already several attempts have been made to improve the resorption behaviour of calcium phosphate cements by increasing the porosity of the material. In this investigation a mixture of NaHCO3 and citric acid monohydrate was added to the apatite cement component as an effervescent additive for producing interconnected macropores into the cement matrix. Mercury intrusion porosimetry was employed to determine pore volume and pore size distribution in …the calcium phosphate cement (CPC) samples. Results showed that addition of only 10 wt % of the effervescent additive (based on the cement powder) to the CPC components lead to producing about 20 V % macropores (with the ...
Mineral Colour Plates are small thumbnail images of minerals, as well as synthetic compounds and chemical elements, with articles that can be found in the MIROFOSS database. The following table shows all of the PHOSPHATE GROUP minerals found in MIROFOSS organized vertically by colour. Certain minerals may appear in multiple colour categories if the mineral can be found in more then one colour range. Clicking on a mineral plate image will bring you to the corresponding MIROFOSS article. Please note this page may take a while to load on slower computers or with slower internet connections.. The element phosphorus is very important for the basic machinery of life. Thus phosphate minerals, in which phosphorus is oxidized in the phosphate group, are part of a tight geochemical cycle that includes the biosphere, rather like the carbon cycle. Phosphate minerals are those minerals that contain the tetrahedrally coordinated phosphate anion along with the freely substituting arsenate and vanadate. ...
Phosphate minerals are those minerals that contain the tetrahedrally coordinated phosphate (PO43−) anion along with the freely substituting arsenate (AsO43−) and vanadate (VO43−). Chlorine (Cl−), fluorine (F−), and hydroxide (OH−) anions that also fit into the crystal structure. The phosphate class of minerals is a large and diverse group, however, only a few species are relatively common. Phosphate minerals include: triphylite Li(Fe,Mn)PO4 monazite (Ce,La,Y,Th)PO4 hinsdalite PbAl3(PO4)(SO4)(OH)6 pyromorphite Pb5(PO4)3Cl vanadinite Pb5(VO4)3Cl erythrite Co3(AsO4)2·8H2O amblygonite LiAlPO4F lazulite (Mg,Fe)Al2(PO4)2(OH)2 wavellite Al3(PO4)2(OH)3·5H2O turquoise CuAl6(PO4)4(OH)8·5H2O autunite Ca(UO2)2(PO4)2·10-12H2O carnotite K2(UO2)2(VO4)2·3H2O phosphophyllite Zn2(Fe,Mn)(PO4)2•4H2O struvite (NH4)MgPO4·6H2O Xenotime-Y Y(PO4) Apatite group Ca5(PO4)3(F,Cl,OH) hydroxylapatite Ca5(PO4)3OH fluorapatite Ca5(PO4)3F chlorapatite Ca5(PO4)3Cl bromapatite Mitridatite group: ...
Calcium phosphate cements are used as synthetic bone grafts, with several advantages, such as their osteoconductivity and injectability. Moreover, their low-temperature setting reaction and intrinsic porosity allow for the incorporation of drugs and active principles in the material. It is the aim of the present work to: a) provide an overview of the different approaches taken in the application of calcium phosphate cements for drug delivery in the skeletal system, and b) identify the most significant achievements. The drugs or active principles associated to calcium phosphate cements are classified in three groups, i) low molecular weight drugs; ii) high molecular weight biomolecules; and iii) ions ...
Description: Over the recent years significant progress has been made in the development of bioinspired materials and therapeutic approaches. Although some of these new technologies are developed in craniofacial models or have a potential to revolutionize dental and craniofacial medicine, the dental community is not well informed about these new and exciting developments. The goal of this symposium is to provide an update on the current scientific developments, which can lead to novel bioinspired technologies for craniofacial repair and regeneration. Dr. Sfeir (University of Pittsburgh, Pittsburgh, PA) will talk about NanoCaP cements for craniofacial regeneration, which utilize calcium phosphate nanoparticles as carriers for osteogenic molecules. These cements cure at physiological pH and can be resorbed in the body and substituted by bone tissue in a matter of months. These unique properties of tNanoCaP bioinspired cements provide a major improvement over the current calcium phosphate materials ...
Dicalcium phosphate is the calcium phosphate with the formula CaHPO 4 and its dihydrate. The "di" prefix in the common name arises because the formation of the …. ...
The self-assembling properties of thermally-sensitive amphiphilic elastin-like multiblock recombinamers have been combined with the capacities of calcium phosphate binding of the SN(A)15 epitope inspired by the salivary protein statherin. In this regard, the interaction between calcium and phosphate ions was examined in the presence of two hybrid recombinamers. The first recombinamer comprised a simple amphiphilic diblock in which the SN(A)15 epitopes were combined, at the gene level, to the hydrophilic end. This recombinamer can self-assemble into nanoparticles that can control the transformation of amorphous calcium phosphate (ACP) into a fibre-like hydroxyapatite structure. In the other recombinamer, the SN(A)15 domains are distributed along the monomer chain, with the hydrophilic blocks being distributed amongst the hydrophobic ones. In this case, the resulting nanohybrid ACP/recombinamer organises into neuron-like structures. Thus, combining the amphiphilic elastin-like recombinamers to the ...
Advances in Materials Science and Engineering is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of materials science and engineering.
The report generally describes tricalcium phosphate, examines its uses, production methods, patents. Tricalcium phosphate market situation is overviewed;
Osteoporosis, loss of bone density, means that there is a net conversion of bone hydroxyapatite (calcium phosphate crystals) into blood calcium, followed by calcium loss in urine. This means that the continuing development and activity of osteoblasts and osteoclasts is out of control. Osteoblasts develop from stem cells that are also the origin of fat adipocytes. The transcription factor that controls the alternative destiny of these stem cells is PPARgamma. Omega-6 fatty acids are converted into molecules that stimulate PPARgamma and result in adipocyte production in bone marrow instead of osteoblasts. In general terms, vegetable oil (except olive oil) makes fat cells instead of bone cells. This is particularly true in postmenopausal women. It is no wonder that the emphasis on the use of vegetable oils to avoid saturated fats has resulted in a pandemic of osteoporosis ...
Pemfs repair bone fracture non-union and enhances bone tissue formation, through enhancement of the formation of calcium phosphate crystal seeds in the bone. Later in chapter 2 for a easy 90k must have 10k to do gil go to guadosalam. Adding these equations together gives the equations most rated seniors online dating website for the cycloid. This extends north-north-west from hungerford on the new south wales border, west of the townships of cunnamulla, quilpie, longreach and winton, to kynuna, a distance of about km. We use cookies to personalise content, to provide social media features and to analyse website traffic. Recommend this website if you like this website, then please support newest dating online website for seniors it by giving it a like. This is fl japanese senior online dating service used in the threshold configuration to dispatch notifications about missing values, see collectd-threshold 5 for details. Thus, an equipotential would contain both points a and b as they have the ...
Isododecane, Bis-Hydroxylauryl Dimethicone/Ipdi Copolymer, Cyclopentasiloxane, Dimethicone, Disteardimonium Hectorite, Mica, CI 77891 / Titanium Dioxide, Silica, Tridecyl Trimellitate, Cyclohexasiloxane, Nylon-12, Dicalcium Phosphate Dihydrate, CI 77491, CI 77492, CI 77499 / Iron Oxides, Trimethylsiloxysilicate, Propylene Carbonate, Dimethicone/Vinyl Dimethicone Crosspolymer, CI 15850 / Red 7 Lake, Silica [Nano] / Silica, Diisopropyl Dimer Dilinoleate, Alumina, CI 45380 / Red 22 Lake, CI 45410 / Red 28 Lake, Ascorbyl Palmitate, CI 42090 / Blue 1 Lake.. ...
Biodegradable beta-tricalcium phosphate disks (TCP) of 2 configurations were inserted into 15mm diameter craniotomy wounds and non-treated control sites were evaluated in 60 rabbits. There were no adverse tissue reactions and no apparent difference in the clinical appearance of the 12 and 24 week implanted disks. By 36 weeks and continuing to 48 weeks, the omnidirectional TCP (OTCP) implants were degrading more rapidly than the unidirectional TCP (UTCP) implants, with degradation progressing centripetally and replacement by woven bone and maturing lamellar bone. Host implant interface of both TCP configurations was a bone bond without interposed soft tissue. TCP disks may be clinically useful for craniotomy repair. Key words: Bone regeneration, tricalcium phosphate disks, calvaria; osteogenesis.*CALCIUM COMPOUNDS
Open wide! Dental filling of the future kills bacteria and regenerates tooth Filling contains calcium phosphate nanoparticles that rebuild tooth minerals , UPDATED: 09:44 GMT, 4 May 2012 The dreaded trip to the dentist to replace a worn-out filling could soon be a thing of the past, thanks to a dental breakthrough. ...
The 3i T3 Implant is a contemporary hybrid implant. It features a media blasted surface for coarse 10+ micron topography along with a dual acid-etched 1-3 micron peek-to-peek surface and a 0.01-0.1 micron discrete crystalline deposition of calcium phosphate nanoparticles. ...
F1147 - 05(2017)e1 Standard Test Method for Tension Testing of Calcium Phosphate and Metallic Coatings , adherence, ceramic materials, hydroxylapatite, interface, porous coating, tension testing, tribasic calcium phosphate,,
Calcium phosphate transfection kits that provide high quality, pretested reagents suitable for both transient and stable transfections. Transfection reagent for calcium phosphate precipitiation engables high efficiency and low toxicity.
Calcium phosphate transfection kits that provide high quality, pretested reagents suitable for both transient and stable transfections. Transfection reagent for calcium phosphate precipitiation engables high efficiency and low toxicity.
Calcium Phosphate Transfection for CV1 CELLS - posted in Cell Biology: hI! Someone knows a Calcium Phosphate Transfection Protocol for CV1 CELLS (African Green Monkey kidney cells), it would be very helpful. ThanksJUYASTICK
Poster presented at 12th Annual Conference of the Materials Research Society of Serbia - YUCOMAT 2010, Herceg Novi, Montenegro, September 6-10, 2010.
The Global Dicalcium Phosphate Industry Report 2015 is a professional and in-depth study on the curre - Market Research Reports and Industry Analysis
TY - JOUR. T1 - Lanthanum phosphate deposition in the duodenum. AU - Iwamuro, Masaya. AU - Tanaka, Takehiro. AU - Urata, Haruo. AU - Kimoto, Katsuhiko. AU - Okada, Hiroyuki. PY - 2016. Y1 - 2016. UR - http://www.scopus.com/inward/record.url?scp=84978864669&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84978864669&partnerID=8YFLogxK. U2 - 10.1016/j.gie.2016.06.012. DO - 10.1016/j.gie.2016.06.012. M3 - Article. C2 - 27339946. AN - SCOPUS:84978864669. JO - Gastrointestinal Endoscopy. JF - Gastrointestinal Endoscopy. SN - 0016-5107. ER - ...
Hydroxyapatite (HA), the main mineral phase of mammalian tooth enamel and bone, originates in body fluids from amorphous calcium phosphate (ACP). ACP presents short-range order in the form of small domains with size of 0.9 nm and chemical formula Ca9(PO4)6, known as Posners clusters. In this study, the aggr
Annexe Chem Pvt Ltd. started in 2008 as leading manufacturer,supplier,exporter of Disodium Hydrogen Phosphate AR from Vadodara,Gujarat,India.The quality of the ingredients used and the final Disodium Hydrogen Phosphate AR is thoroughly tested by our quality analysts.
Global phosphorus (P) should be managed more sustainably to secure food, energy, and water for a growing population. Despite the abundance of calcium in most environments, we have not fully utilized its thermodynamic stability to form calcium phosphate minerals (CaP) for aqueous P management. In this study, we show
Monocalcium Dicalcium Tricalcium Calcium Phosphate Monobasic Dibasic Tribasic USP NF BP IP ACS Analytical Reagent FCC Food Grade Manufacturers, USA India
A comparative study on the tapering of natural quartz and potassium dihydrogen phosphate (KDP) crystals has been made. Both tapered natural quartz crystals and KDP crystals display similar surface microtopography featuring a large number of tiny elongated growth islands and striations on the tapered regions. In addition to the well accepted fact that trivalent metallic ions in aqueous solution can cause the tapering of KDP crystals, we find that Pb2+ has the same effect. This possibly originates from preferentially settled impurities and embryonic crystallites along the edges between two major faces. © 1995 ...
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...
Gene therapy is recognized as a medical approach for the treatment of diseases that are difficult to cure, such as tumors. Several viral and non-viral carriers for gene transfer have been developed for either in vivo or ex vivo/in vitro use [1-4]. The most important viral carriers, characterized in laboratory studies and clinical trials, have been inactivated retroviruses, adenoviruses, adeno-associated viruses, and herpes viruses. These viruses show relatively high transfection efficiency, but have some clinical safety problems. On the other hand, non-viral methods of gene delivery, including cationic lipofection, calcium phosphate precipitation, gene guns, and injection of naked DNA, generally show low transfection efficiency but are not pathogenic [1-4]. However, there is another serious issue regarding the present gene delivery methodologies. Almost all the gene delivery methods currently developed have insufficient ability to specifically recognize and target diseased cells and to ...
Construction of clones and HEK transfection.α0 (cSlo1, GenBank numberU23821) was cloned by homology screening of a chick cochlear cDNA library (Jiang et al., 1997). Chimeric splice variant clones were constructed by inserting "exon-present" RT-PCR products into the α0 cDNA by ligation of the restricted products. Final sequence of each chimeric construct was confirmed using primers upstream of the added exons. Plasmids for expression in the mammalian HEK293 cell line were created by packaging the full-length cDNA clone into pcDNA 3.1 (Invitrogen, Carlsbad, CA). Before recording, cells were propagated in DMEM (Life Technologies, Gaithersburg, MD) supplemented with 10% fetal bovine serum (Life Technologies). Cells were transfected using calcium phosphate precipitation. The mixture included green fluorescent protein (GFP) cDNA (pGreenLantern, Life Technologies) to label transfected cells. Recordings were made 24-48 hr after transfection.. The quail β subunit of the slo protein (GenBank accession ...
1. The aim of the present study was to investigate noradrenaline (NA)-induced regulation of alpha(1) -adrenoceptor (AR) mRNA expression in human embryonic kidney (HEK) 293 cells stably expressing cloned alpha(1) -AR subtypes with similar receptor densities. Stable transfection was performed by calcium phosphate precipitation. Receptor expression was detected by radioligand binding assay. The mRNA expression was measured by RNase protection assay.. 2. alpha(1) -Adrenoceptor subtype mRNA respond in distinct ways following prolonged exposure to NA. The mRNA level of the alpha(1A) -AR subtype was unchanged, the mRNA level of the alpha(1B) -AR subtype was increased and the mRNA level of the alpha(1D) -AR subtype declined time dependently. The protein kinase C (PKC) inhibitor calphostin C or RO 31-8220 abolished the NA-induced downregulation of alpha(1D) -AR mRNA. Phorbol myristate acetate (PMA), a PKC activator, similarly repressed the effects of NA on alpha(1D) -AR. However, calphostin C, RO 31-8220 ...
Experimental. Reagent material. Methanol, dichloromethane, ethanol, acetic acid were HPLC grade; disodium hydrogen phosphate, sodium dihydrogen phosphate were of analytical grade; ultra-pure water; blood;. Acetic acid - solution: Take 50 mL of deionized water with acetic acid adjusted to pH = 6;. Disodium hydrogen phosphate solution: 0.1 mol/L, weighed 35.81 g disodium hydrogen phosphate (Na2HPO4 • 12H2O), dissolved in water and dilute to 1 L;. Sodium dihydrogen phosphate solution: 0.1 mol/L, weighed 15.60 g disodium hydrogen phosphate (Na2HPO4 • 12H2O), dissolved in water and dilute to 1 L;. 0.1 mol/L phosphate buffer solution (pH = 6): The 1.70 g of dibasic sodium phosphate and 12.14 g sodium dihydrogen phosphate was dissolved in 800 mL of deionized water, and then diluted with deionized water to 1 L, mix well. pH adjusted to 6.0 (with 0.1 mol/L sodium dihydrogen phosphate to lower pH; with 0.1 mol/L disodium hydrogen phosphate to increase the pH);. Hypnotic standard stock solution: mixed ...
Phosphate minerals WikipediaPhosphate minerals are those minerals that contain the tetrahedrally coordinated phosphate (PO43−) anion along with the freely substituting arsenate (As
The present thesis was focused on the design and development of novel porous bioactive ceramic materials and scaffolds addressed to the regeneration of large and load-bearing bone defects. This research was carried out to meet the increasing demand for bioactive scaffolds enabling bone regeneration, due to the several drawbacks affecting the use of autologous bone, especially for large bone reconstruction. Nowadays, it is well established that effective tissue regeneration requires the implantation of scaffolds exhibiting tissue-mimicking compositional, morphological and mechanical features to promote the formation and maturation of new healthy tissue. In this context, my work was organized in three research topics on the basis of specific clinical requirements, thus leading to the development of different types of bioceramic scaffolds based on calcium phosphates, particularly: i) macroporous implants for cranio-maxillofacial defects obtained by direct foaming of ceramic suspensions, ii) 3D ...
The objective of this work was to fabricate gelatin and alpha-tricalcium phosphate (α-TCP) scaffolds via freeze-drying technique. Both materials are well known to be promising candidates for tissue engineering and drug delivery applications. One of the main characteristics that we look for in scaffolds and drug delivery systems is the formation of an adequate porosity. The role of this porosity is to ensure cell colonisation, flow transport of nutrients and metabolic waste in scaffolds for tissue engineering and to enhance the loading capacity and delivery rate in delivery systems. Two types of scaffolds were produced: one of organic matrix reinforced by an inorganic phase (α-TCP) and the other of inorganic matrix (α-TCP) with gelatin as a binder. Organic phase plays an important role in the toughness of bone whereas inorganic phase enhances its mechanical properties. The aim was to produce scaffolds with organic matrix and enhance the existing process, and also create new scaffolds with ...
Research Report on EMEA (Europe, Middle East and Africa) Tricalcium Phosphate (TCP) Market Report 2017. The Report includes market price, demand, trends, size, Share, Growth, Forecast, Analysis & Overview.
Source: RSC Chemistry World With 70% of bone consisting of a calcium phosphate mineral called hydroxyapatite, calcium phosphate cements (CPCs) are widely used
Bones are composed of collagen fibers in which calcium phosphate is deposited in the form of nanocrystals.. Previously it was thought that collagen was only a template for the deposition of calcium phosphate and that bone formation was controlled by specialized biomolecules.. Now, a team of researchers from Eindhoven University of Technology (TU/e) and the University of Illinois was successfully able to mimic the growth of calcium phosphate inside the collagen in the laboratory, just as it happens in the human body.. The researchers found that collagen fibers control the mineral formation process and thereby direct bone formation. On the other hand, the biomolecules was found to have a different role in the mineralization process: they keep the calcium phosphate in solution until mineral growth starts.. ...
Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste ...
Orthobiologic and bone graft product testing, research and development support undertaken, with regulatory testing and certification services implemented. Orthobiologic and bone graft products are sophisticated, highly pure biomaterials often based on calcium phosphate (hydroxyapatite) composites and other biomaterials which are typically bioengineered to mimic the structure of human bone to optimise bone regeneration. There are three major types of bone grafts: autografts, allografts, and bone substitute. Depending on their properties, preparation and application, bone grafts help bone to regrow via different healing processes such as osteoconduction, where the bone grows on a surface. These products are often used in conjunction with a growth factor or recombinant protein based therapeutic.. Regulatory authorities expect that all risks to health generally associated with the use of the bone graf material devices - such as ineffective bone formation or adverse tissue reaction - are addressed ...
A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an effervescent agent. Methods of making the compositions and methods of using the osteogenic compositions to treat osteoporotic and/or osteopenic bone are also disclosed.
Bioactive glass (BG) can directly bond to living bone without fibrous tissue encapsulation. Key mechanistic steps of BGs activity are attributed to calcium phosphate formation, surface hydroxylation and fibronectin (FN) adsorption. In the present study, self-assembled monolayers (SAMs) of alkanesilanes with different surface chemistry (OH, NH2 and COOH) were used as a model system to mimic BGs surface activity. Calcium phosphate (Ca-P) was formed on SAMs by immersion in a solution that simulates the electrolyte content of physiological fluids. FN adsorption kinetics and monolayer coverage was determined on SAMs with or without Ca-P coating. The surface roughness was also examined on these substrates before and after FN adsorption. The effects of FN-adsorbed, Ca-P-coated SAMs on the function of MC3T3-E1 were evaluated by cell growth, expression of alkaline phosphatase activity and actin cytoskeleton formation. We demonstrate that, although the FN monolayer coverage and the root mean square (rms)
Page contains details about calcium phosphate/protein hybrid flower-shaped nanoparticles . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
Of note in this discussion, however, is the immune systems response to the presence of calcium crystals in developing atherosclerotic lesions in arteries. Cells called macrophages which are first responders to bodily harm show up early in the course of blood vessel injury and set immediately to work eating foreign invaders Pac-Man style. As they gobble up various harmful substances such as oxidized LDL cholesterol or basic calcium phosphate (BCP) crystals, they send out proinflammatory cytokines which are chemical messenger molecules that further activate an immune response. This is a good thing with regards to incoming foreign bodies such as bacteria or dirt from the sidewalk when youve fallen and scraped your knee, but not so good when its an ongoing assault from various environmental insults such as LDL-cholesterol, trans-fats, cigarette smoke, or...too much calcium (more on this later). The inflammation from BCP crystals in activated macrophages "may lead to a positive feed-back loop of ...
Abstract(#br)Protein-coated microcrystals (PCMCs) were investigated as potential vaccine formulations for a range of model antigens. Presentation of antigens as PCMCs increased the antigen-specific IgG responses for all antigens tested, compared to soluble antigens. When compared to conventional aluminium-adjuvanted formulations, PCMCs modified with calcium phosphate (CaP) showed enhanced antigen-specific IgG responses and a decreased antigen-specific IgG1:IgG2a ratio, indicating the induction of a more balanced Th1/Th2 response. The rate of antigen release from CaP PCMCs, in vitro , decreased strongly with increasing CaP loading but their immunogenicity in vivo was not significantly different, suggesting the adjuvanticity was not due to a depot effect. Notably, it was found that CaP... modification enhanced the phagocytosis of fluorescent antigen-PCMC particles by J774.2 murine monocyte/macrophage cells compared to soluble antigen or soluble PCMCs. Thus, CaP PCMCs may provide an alternative to ...
Efficient delivery of growth factors from carrier biomaterials depends critically on the release kinetics of the proteins that constitute the carrier. Immobilizing growth factors to calcium phosphate ceramics has been attempted by direct adsorption and usually resulted in a rapid and passive release of the superficially adherent proteins. The insufficient retention of growth factors limited their bioavailability and their efficacy in the treatment of bone regeneration. In this study, a coprecipitation technique of proteins and calcium phosphate was employed to modify the delivery of proteins from biphasic calcium phosphate (BCP) ceramics. To this end, tritium-labeled bovine serum albumin ([3H]BSA) was utilized as a model protein to analyze the coprecipitation efficacy and the release kinetics of the protein from the carrier material. Conventional adsorption of [3H]BSA resulted in a rapid and passive release of the protein from BCP ceramics, whereas the coprecipitation technique effectively ...
TY - JOUR. T1 - Effect of platelet-rich plasma on the healing of intrabony defects treated with beta tricalcium phosphate and expanded polytetrafluoroethylene membranes. AU - Döri, Ferenc. AU - Huszár, Tamás. AU - Nikolidakis, Dimitris. AU - Tihanyi, Dora. AU - Horváth, Attila. AU - Arweiler, Nicole B.. AU - Gera, I.. AU - Sculean, Anton. PY - 2008/4. Y1 - 2008/4. N2 - Background: Regenerative periodontal therapy using platelet-rich plasma (PRP) and different types of bone substitutes with or without guided tissue regeneration (GTR) has been proposed as a modality to enhance the outcome of regenerative surgery. However, there are limited data from controlled clinical studies evaluating the effect of PRP on the healing of deep intrabony defects treated with a combination of bone substitutes and GTR. The aim of this study was to clinically evaluate the effect of PRP on the healing of deep intrabony defects treated with beta tricalcium phosphate (β-TCP) and GTR by means of a non-bioresorbable ...
No. of Report Pages: 126. Price (Single User Licence): $ 2900. Purchase the Synthetic Dental Bone Graft Substitute Market Report at: https://www.absolutereports.com/purchase/10555586 Several important topics included in the Synthetic Dental Bone Graft Substitute Industry research report are as follows:. • Overview of Synthetic Dental Bone Graft Substitute Industry. • Market Size (Value and Volume) analysis of Synthetic Dental Bone Graft Substitute Industry. • Synthetic Dental Bone Graft Substitute Industry Competition by Manufacturers, Type and Application. • Synthetic Dental Bone Graft Substitute Industry Major Regions Volume, Value and Sales Price Analysis. • Synthetic Dental Bone Graft Substitute Industry Technology and Development Trend. • Research Findings and Conclusion of Synthetic Dental Bone Graft Substitute Industry. To sum it up, the report concludes with an all-inclusive research result on the industry chain of Synthetic Dental Bone Graft Substitute Industry facilitating ...
Patients with Amyotrophic Lateral Sclerosis (ALS) typically endure a progressive paralysis due to the continued loss of motoneurons that leads them to death in less than 5 years. No treatment has changed its natural history. Intrathecal injection of umbilical cord mesenchymal stem cells can secret trophic factors that keep the motorneurons functional. The investigators have designed a phase I/II clinical trial to check the feasibility of this approach in humans ...
imibond f zinc phosphate cement manufacturers imibond f zinc phosphate cement suppliers Directory - Browse imibond f zinc phosphate cement products,Choose Quality imibond f zinc phosphate cement manufacturers, suppliers, factory at B2BAGE
Multimineral amino acid blend (providing calcium carbonate, magnesium oxide, ferrous sulphate, zinc oxide, manganese carbonate, copper sulphate, potassium iodide, sodium selenite, chromium chloride, sodium molybdate complexed with citric acid, glycine, rice flour, rice protein complex, sodium hydroxide, sodium citrate, aspartic acid and maltodextrin), di-Calcium Phosphate, Bulking agent: Microcrystalline cellulose, Vitamin C (with hydroxypropylmethylcellulose), Niacin (as niacinamide), Vitamin E (natural source vitamin E from non-GM soya), Magnesium Stearate, Lutein, Pantothenic Acid, Beta-carotene (with D-α-tocopherol, sodium ascorbate, ascorbyl palmitate, corn starch, glucose), Vitamin B12 (with dicalcium phosphate), Biotin (with di-calcium phosphate), Vitamin B6, Thiamin, Vitamin D3 (with arabic gum, tricalcium phosphate, D-α-tocopherol), Folic Acid (with dicalcium phosphate), Tablet coating (Glazing agent: Hydroxypropylmethylcellulose, Colour: Titanium Dioxide, Stearic Acid, Bulking agent: ...
TY - JOUR. T1 - Biomimetic remineralization of resin-bonded acid-etched dentin. AU - Tay, F. R.. AU - Pashley, D. H.. PY - 2009/8/1. Y1 - 2009/8/1. N2 - Degradation of denuded collagen within adhesive resin-infiltrated dentin is a pertinent problem in dentin bonding. A biomimetic remineralization scheme that incorporates non-classic crystallization pathways of fluidic amorphous nanoprecursors and mesoscopic transformation has been successful in remineralizing resin-free, acid-etched dentin, with evidence of intrafibrillar and interfibrillar remineralization. This study tested the hypothesis that biomimetic remineralization provides a means for remineralizing incompletely infiltrated resin-dentin interfaces created by etch-and-rinse adhesives. The remineralization medium consists of a Portland cement/simulated body fluid that includes polyacrylic acid and polyvinylphosphonic acid biomimetic analogs for amorphous calcium phosphate dimension regulation and collagen targeting. Both interfibrillar ...
Learn more about Calcium Pyrophosphate Dihydrate Deposition Disease at Medical City Dallas DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
TY - JOUR. T1 - Direct visualization of calcium oxalate monohydrate crystallization and dissolution with atomic force microscopy and the role of polymeric additives. AU - Guo, Shouwu. AU - Ward, Michael. AU - Wesson, Jeffrey A.. PY - 2002/5/28. Y1 - 2002/5/28. N2 - The growth and dissolution of calcium oxalate monohydrate (COM) were investigated by real-time in situ atomic force microscopy (AFM). The (100) surfaces of COM crystals were sufficiently rough that direct AFM imaging of terrace growth and step motion was not feasible. In undersaturated aqueous solutions, however, COM crystals dissolved, developing elongated hexagonal pits oriented along the [001] direction and having perimeters defined by {010} and {021} planes, which mimics the habit of the macroscopic crystals. Increasing the concentration of calcium oxalate to supersaturated levels reversed etching, resulting in gradual filling of the pits, which is tantamount to crystal growth. The confinement of growth within the pits permitted ...
... calcium phosphate stones have the greatest density, followed by calcium oxalate and magnesium ammonium phosphate stones. ... Calcium-containing stones[edit]. By far, the most common type of kidney stones worldwide contains calcium. For example, calcium ... Sufficient dietary intake of magnesium and citrate inhibits the formation of calcium oxalate and calcium phosphate stones; in ... As with adults, most pediatric kidney stones are predominantly composed of calcium oxalate; struvite and calcium phosphate ...
Bones are mainly composed of calcium phosphate. The phosphate reacts with the acid, and the calcium is excreted by the kidneys. ... and calcium-rich foods. In particular, the B vitamins, calcium, and vitamin D must be artificially supplemented. This is ... The urine has a low pH, which stops uric acid from dissolving, leading to crystals that act as a nidus for calcium stone ... Excess calcium in the urine (hypercalciuria) occurs due to increased bone demineralisation with acidosis. ...
"Endocrinology: hormonal control of calcium and phosphate. Medical College of Georgia. Diarsipkan dari versi asli tanggal ... Carney SL (1997). "Calcitonin and human renal calcium and electrolyte transport". Miner Electrolyte Metab. 23 (1): 43-7. PMID ... Copp DH, Cheney B (January 1962). "Calcitonin-a hormone from the parathyroid which lowers the calcium-level of the blood". ... Disorders of the Parathyroid Gland and Calcium Homeostasis". Dalam Dan L. Longo; Dennis L. Kasper; J. Larry Jameson; Anthony S ...
This cleaves the phosphate groups and acts as the foci for calcium and phosphate deposition. The vesicles then rupture and act ... The matrix is hardened by the binding of inorganic mineral salt calcium phosphate in a chemical arrangement known as calcium ... Bones, in particular after calcination to bone ash, are used as source of calcium phosphate for the production of bone china ... The inorganic composition of bone (bone mineral) is primarily formed from salts of calcium and phosphate, the major salt being ...
... -derived compounds are used in tooth remineralization products to stabilize amorphous calcium phosphate (ACP) and release ... Chhabra N, Chhabra A (2018). "Enhanced Remineralisation of Tooth Enamel Using Casein Phosphopeptide-Amorphous Calcium Phosphate ... 2006). "Increased remineralization of tooth enamel by milk containing added casein phosphopeptide-amorphous calcium phosphate ... however companies could opt to use calcium caseinate to increase calcium content and decrease sodium levels in their products.[ ...
Common materials used for bioceramics include alumina, zirconia, calcium phosphate, glass ceramics, and pyrolytic carbons. One ...
High levels of phosphate induce secondary hypoparathyroidism, resulting in low levels of calcium in the blood. This causes ... Sphingosine-1-phosphate (S1P) has shown similar effect, but its mechanism of inhibiting the sphingomyelin apoptotic pathway may ... The building blocks are nucleotides; a molecule comprising a nucleobase, a sugar and a phosphate group. The nucleobases are ... Following this, high levels of uric acid, potassium and phosphate are found in the blood. ...
"The role of sphingosine-1-phosphate and ceramide-1-phosphate in calcium homeostasis". Current Opinion in Investigational Drugs ... and the phosphatidylinositol phosphates (PIPs), involved in calcium-mediated activation of protein kinase C;[76] the ... Berridge MJ, Irvine RF (September 1989). "Inositol phosphates and cell signalling". Nature. 341 (6239): 197-205. doi:10.1038/ ... Polyprenol phosphate sugars and polyprenol diphosphate sugars function in extra-cytoplasmic glycosylation reactions, in ...
Chemical products such as, chloroaniline, calcium phosphate, sulphuric acid, Single super phosphate etc. Vapi Aarti Industries ...
This leads to a greater resorption of calcium and phosphate ions. High levels of calcium in the blood, on the other hand, leads ... Vitamin D increases absorption of calcium and phosphate in the intestinal tract, leading to elevated levels of plasma calcium, ... High levels of calcium, magnesium, phosphate and products of collagen will be released into the extracellular fluid as the ... depending on the demand for calcium. Calcium-sensing membrane receptors in the parathyroid gland monitor calcium levels in the ...
Because of the hyperphosphatemia, calcium is precipitated to form calcium phosphate, leading to hypocalcemia. Symptoms of ... Hyperphosphatemia causes acute kidney failure in tumor lysis syndrome, because of deposition of calcium phosphate crystals in ... Tumor lysis syndrome is characterized by high blood potassium (hyperkalemia), high blood phosphate (hyperphosphatemia), low ... 12 mg/dL and phosphate , 6 mg/dL). Acute uric acid nephropathy is associated with little or no urine output. The urinalysis may ...
A calcium phosphate-rich passivation layer gradually forms over the surface of the glass, preventing further leaching. ... 5) Mineralization in which the calcium phosphate layer gradually transforms into crystalline hydroxyapatite, that mimics the ... 4) Precipitation in which an amorphous calcium phosphate layer is deposited on the gel. ... The 45S5 name signifies glass with 45 wt.% of SiO2 and 5:1 molar ratio of Calcium to Phosphorus. Lower Ca/P ratios do not bond ...
Later calcium and sodium phosphates became used; bone ash contains calcium phosphate in a high proportion. Calcium fluoride was ... Ancient milk glasses used crystals of calcium antimonate, formed in the melt from calcium present in the glass and an antimony ... Fluorides of aluminium, calcium, barium, and magnesium can be used with suitable heat treatment. Tin oxide can be used, but ...
2001 - The start of production of dicalcium phosphate. 2002 - Starts production of mono-calcium phosphate. 2002 - The majority ... 2005 - A product of the plant - Mono calcium Phosphate - a gold medal in the contest "Product of the Year". 2006 - Innovation ... Diammonium phosphate Aluminium fluoride Wet-process phosphoric acid Technical grade sulphuric acid Monocalcium phosphate 1959 ... Lifosa is a phosphate industry company based in Kėdainiai, Lithuania. Starting business in 1952 as a state-owned enterprise of ...
... calcium carbonate (CaCO3), various calcium hydrogen phosphates, various silicas and zeolites, and hydroxyapatite (Ca5(PO4)3OH ... Calcium Phosphate Technologies from. dentist.net. Retrieved on April 4, 2013. Simon Quellen Field "Why There's Antifreeze in ... Hydroxyapatite nanocrystals and a variety of calcium phosphates are included in formulations for remineralization, i.e. the ... Tanagra, containing calcium fluoride as the active ingredient, was sold by Karl F. Toellner Company, of Bremen, Germany, based ...
Bone is calcium phosphate. Fe2+/Fe3+ - haemoglobin, the main oxygen carrying molecule has a central iron ion. NO− 3, source of ... Below is a list of some of the most important ions for living things as well as examples of their functions: Ca2+ - calcium is ... Calcium in biology Magnesium in biology Human Iron Metabolism. ... The shells of sea creatures are calcium carbonate. In blood ...
Calcium phosphates usually found in bioceramics include hydroxyapatite (HAP) Ca10(PO4)6(OH)2; tricalcium phosphate β (β TCP): ... Some calcium-deficient phosphates with an apatite structure were thus commercialised as "tricalcium phosphate" even though they ... Calcium phosphates, oxides, and hydroxides are common examples. Other natural materials - generally of animal origin - such as ... Calcium phosphate-based ceramics constitute, at present, the preferred bone substitute in orthopaedic and maxillofacial surgery ...
6250 6250 BCE". Besim Ben-Nissan (17 April 2014). "Advances in Calcium Phosphate Biomaterials". Springer Science & Business. p ...
Struvite stones are composed of a combination of magnesium ammonium phosphate (struvite) and calcium carbonate-apatite. ... can be sustained only when ammonia production is increased and the urine pH is elevated to decrease the solubility of phosphate ...
Perlstein, D. (2015). "Rickets (Calcium, Phosphate, or Vitamin D Deficiency) Pg 1". Inglis, V.; Ball, K.; Crawford, D. (2005 ... Calcium's most essential function relates to the growth and strengthening of muscles and bones, with 1% of calcium also ... which build calcium into the bone matrix. Early onset calcium deficiency can result in children developing brittle bones, ... Calcium is a nutrient that can be gained through the consumption of primarily milk and cheeses, however, can also be derived ...
They are both responsible for calcium and phosphate balance. In mammals the predominant function of STC1 is to activate ... Increase in the serum calcium triggers the release of stanniocalcin. Unlike calcitonin, it also regulates phosphate level. It ... In bony fishes, stanniocalcin is the principal hormone that regulate calcium level. Even though other calcium-decreasing ... is a family of hormones which regulate calcium and phosphate balance in the body. The first stanniocalcin discovered was from ...
... calcium phosphate is referred to as dicalcium phosphate. A dibasic acid is an acid that has two hydrogen ions to donate ...
They include cream of tartar, calcium phosphate, and citrates. High-temperature acid salts produce a leavening effect during ... monosodium phosphate (NaH2PO4), and disodium phosphate (Na2HPO4). Often acid salts are used as buffers. For example, the acid ... baking and are usually aluminium salts such as calcium aluminium phosphate. Some acid salts may also be found in non-dairy ...
January 2005). "Effects of sevelamer and calcium-based phosphate binders on uric acid concentrations in patients undergoing ...
Methods of artificial transfection include (a) chemical methods, including calcium phosphate precipitation, DEAE-dextran ... Bacteria can also be made competent through a variety of chemical treatments including exposure to calcium ions, or a mixture ...
Vitamin D ensures that serum phosphate and calcium levels are sufficient to facilitate the mineralization of bone. Congenital ... Treatment involves increasing dietary intake of calcium, phosphates and vitamin D. Exposure to ultraviolet B light (most easily ... Serum calcium may show low levels of calcium, serum phosphorus may be low, and serum alkaline phosphatase may be high from ... If due to a lack of vitamin D, treatment is usually with vitamin D and calcium. This generally results in improvements within a ...
Calcium Scandium Titanium Vanadium Chromium Manganese Iron Cobalt Nickel Copper Zinc Gallium Germanium Arsenic Selenium Bromine ... The principal commercially viable ore of lutetium is the rare-earth phosphate mineral monazite, (Ce,La,etc.)PO4, which contains ... in which all the elements have relationship similar to that of elements of the calcium-strontium-barium-radium series, the ...
Overwintering juveniles store calcium and phosphates in it for molting. Silicon is present throughout the life, but decreases ... In some harvestmen (Phalangium, Odiellus and Leiobunum) it contains calcium deposits. The endosternite is U-shaped, with the ...
Basic Calcium Phosphate Crystals Induce Osteoarthritis-Associated Changes in Chondrocyte Phenotype through Activation of ... Basic Calcium Phosphate Crystals Induce Osteoarthritis-Associated Changes in Chondrocyte Phenotype through Activation of ... Calcium/Calmodulin Kinase 2. Rong, Jing ; Pool, Bregtina ; Zhu, Mark ; Munro, Jacob ; McCarthy, Geraldine M ; Cornish, Jillian ...
Find out what health conditions may be a health risk when taken with Calcium Phosphate-Vitamin D3 Oral ... WebMD provides common contraindications for Calcium Phosphate-Vitamin D3 Oral. ... Calcium. contraindications. Who should not take Calcium?. Check with your physician if you have any of the following:. ... Treatment by Condition Related to Calcium Phosphate-Vitamin D3. *Prevention of Vitamin D Deficiency Medications ...
A list of US medications equivalent to Calcium Hydrogen Phosphate is available on the Drugs.com website. ... Calcium Hydrogen Phosphate is a medicine available in a number of countries worldwide. ... Calcium Hydrogen Phosphate and Colecalciferol). Merck, Indonesia. *Dagravit D Calcium (Calcium Hydrogen Phosphate and Calcium ... Dibasic Calcium Phosphate Ebisu. Nikko Seiyaku, Japan. *Dibasic Calcium Phosphate Hydrate Yoshida Seiyaku. Yoshida Seiyaku, ...
The kind of calcium in your bones and teeth is calcium phosphate, a compound of calcium and phosphorous. Learn whether this ... means taking calcium phosphate supplements can give you healthier bones. ... Your body contains 1.2 to 2.5 pounds of calcium. Most of it, 99 percent, is in your bones and teeth. ... Is calcium phosphate the answer?. "In most cases, calcium phosphate offers no advantage over calcium carbonate or calcium ...
Calcium and phosphate in renal failure. Br Med J 1971; 2 :725 ... Calcium and phosphate.... *Calcium and phosphate in renal ... Calcium and phosphate in renal failure.. Br Med J 1971; 2 doi: https://doi.org/10.1136/bmj.2.5764.725-a (Published 26 June 1971 ...
... any of several phosphates of calcium occurring naturally in some rocks and in animal bones, used as a fertilizer and food ... any calcium salt of a phosphoric acid. Calcium phosphates are found in many rocks and used esp in fertilizers ... Calcium phosphate is deliquescent, and will dissolve in the water it absorbs from the atmosphere if it is not kept in a closed ... any of several phosphates of calcium occurring naturally in some rocks and in animal bones, used as a fertilizer and food ...
... calcium circulates in different forms. Of the plasma calcium, roughly 40 percent is bound to albumin, 15 percent is com ... The maintenance of calcium and phosphate homeostasis involves intestinal, bone, and renal handling of theseions.Within the ... However, it is the plasma concentrations of ionized calcium and inorganic phosphate that are under hormonal control. Calcium ... calcium. As routinely measured in the laboratory, the plasma calcium concentration includes all of the calcium in the plasma ( ...
Monocalcium phosphate, monohydrate Formula: Ca(H2PO4)2 • H2O Formula Wt.: 252.07 CAS: 10031-30-8 Characteristic: White solid ... Synonym: Monocalcium phosphate, monohydrate. Formula: Ca(H2PO4)2 • H2O. Formula Wt.: 252.07. CAS: 10031-30-8. Characteristic: ... Synonym: Monocalcium phosphate, monohydrate. Formula: Ca(H2PO4)2 • H2O. Formula Wt.: 252.07. CAS: 10031-30-8. Characteristic: ...
... dissolving calcium phosphate does not consist of pounding it into pieces. However, dissolving calcium phosphate outside the ... Calcium phosphate is welcome in the body, when found in tooth enamel and bones. But when calcium phosphate deposits in the ... dissolving calcium phosphate does not consist of pounding it into pieces. However, dissolving calcium phosphate outside the ... which includes those formed from calcium phosphates.. Tip. If you have large calcium phosphate deposits or kidney stones, ...
Tricalcium phosphate (tribasic calcium phosphate or tricalcic phosphate, sometimes referred to as calcium phosphate or calcium ... For the function of calcium phosphate in organisms, see Calcium metabolism.. Calcium phosphate is a family of materials and ... collectively referred to as colloidal calcium phosphate (CCP).[2] Various calcium phosphate minerals are used in the production ... Dicalcium phosphate (dibasic calcium phosphate), E341(ii) (CAS# 7757-93-9): CaHPO4 (mineral: monetite) and a dihydrate CaHPO4(H ...
Biological calcium phosphates are, with few exceptions, poorly or partly crystalline and impure, and sometimes comprise a ... Holt, C., Davies, D. T. and Law, A. J. R. (1986). Effect of colloidal calcium phosphate content and free calcium ion ... or octacal-cium phosphate (OCP, Ca8H2(PO4)6· 5H2O). The fascination of biological calcium phosphates arises from the deviations ... Biological calcium phosphates are, with few exceptions, poorly or partly crystalline and impure, and sometimes comprise a ...
Setting times of calcium phosphate cement compositions are enhanced by the addition of phosphate or carbonate lubricant ... calcium carbonate, or a source of phosphate, e.g., tetracalcium phosphate or tricalcium phosphate, a base, such as calcium ... Injectable calcium phosphate cement. US20100121459 *. Nov 12, 2009. May 13, 2010. Garigapati Venkat R. Tetra Calcium Phosphate ... Porous calcium phosphate cement. EP1335757A4 *. Oct 10, 2001. Aug 20, 2003. Howmedica Osteonics Corp. Porous calcium phosphate ...
Tricalcium phosphate (tribasic calcium phosphate or tricalcic phosphate, sometimes referred to as calcium phosphate or calcium ... Calcium phosphate is a family of materials and minerals containing calcium ions (Ca2+) together with inorganic phosphate anions ... collectively referred to as colloidal calcium phosphate (CCP). Various calcium phosphate minerals are used in the production of ... 2 Tetracalcium phosphate (CAS#1306-01-0): Ca4(PO4)2O Calcium phosphates are found in many living organisms, e.g., bone mineral ...
The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an ... the calcium phosphate material is a poorly crystalline apatitic calcium phosphate solid having a calcium-to-phosphate (Ca/P) ... Calcium Phosphate. In one embodiment, the calcium phosphate material is poorly crystalline apatitic (PCA) calcium phosphate. ... The Calcium Phosphate Material. Calcium phosphate component of the present invention may be any biocompatible, calcium ...
... polymer scaffold and osteoclast-resorbable calcium phosphate particles with a binding agent binding the calcium phosphate ... coating calcium phosphate particles with a binding agent, and drying the coated calcium phosphate particles; ... coating calcium phosphate particles with a binding agent, and drying the coated calcium phosphate particles; ... In this aspect of the invention the calcium phosphate particles may be osteoclast-resorbable calcium phosphate particles. ...
Antibacterial property expressed by a novel calcium phosphate glass.. Liu L1, Pushalkar S, Saxena D, LeGeros RZ, Zhang Y. ... We have developed a calcium phosphate glass (CPG) doped with Zn(2+) or F(-) or combined Zn(2+) and F(-) ions, which are ... Comparison of XRD spectra among calcium phosphate glasses.. Antibacterial Property Expressed by a Novel Calcium Phosphate Glass ...
... which include calcium phosphate particles having a diameter of 0.05 to 100 microns, wherein said calcium phosphate particles on ... A calcium phosphate cement suitable for use in dental and bone prosthesis is disclosed, ... anhydrous calcium hydrogen phosphate, calcium hydrogen phosphate hydrate, calcium pyrophosphate, calcium triphosphate, calcium ... Suitable calcium phosphates for use as the calcium phosphate powder or small pieces of calcium phosphate in the present ...
... includes calcium phosphate, tribasic description, dosage and directions. ... Calcium phosphate, tribasic. Generic Name: calcium phosphate, tribasic (tricalcium phosphate) (KAL see um FOSS fate, tri BAY ... Calcium phosphate is used to prevent and to treat calcium deficiencies.. Calcium phosphate may also be used for purposes not ... What other drugs will affect calcium phosphate?. Calcium phosphate can make it harder for your body to absorb other medications ...
... the calcium phosphate compositions are remodeled into bone. Methods for using the calcium phosphate compositions, e.g., to ... In addition to calcium phosphate, the compositions include an effervescent agent to promote the formation of interconnected ... Porous calcium phosphate implant compositions that approximate the chemical composition of natural bone mineral are provided. ... wherein said calcium phosphate is prepared using an amorphous calcium phosphate and a second calcium phosphate source. ...
The concentration of calcium phosphate is higher in milk than in serum but it rarely forms deposits of insoluble phosphates. ... note CDHA is sometimes termed apatitic calcium triphosphate). The composition of amorphous calcium phosphate is CaxHy(PO4)z· ... Amorphous calcium phosphate (ACP or ATCP) is a glassy precipitate of variable composition that is formed in double ... Amorphous calcium phosphate in combination with casein phosphopeptide has been used as a dental treatment to treat incipient ...
... any of a number of phosphates of calcium found in bones, teeth, etc. and used in medicine and in the manufacture of enamels, ... calcium phosphate. calcium phosphate. any of a number of phosphates of calcium found in bones, teeth, etc. and used in medicine ... plural calcium phosphates). *(inorganic chemistry) The calcium salt or phosphoric acid, Ca3(PO4)2, or of several related acids ... "calcium phosphate." YourDictionary, n.d. Web. 16 January 2019. ,https://www.yourdictionary.com/calcium-phosphate,. ...
... ribose connects RNA bases and forms a strand of sugar phosphates. Accumulation of ribose on prebiotic Earth was difficult ... The stability was not improved further when an 80-fold molar excess of sodium silicate or sodium phosphate was added. Calcium ... The improvement of ribose stability by the removal of Ca2+ and by addition of silicate or phosphate was far smaller than the ... The formation of a complex of silicate (or phosphate) with ribose was also analyzed in experiments with 29Si and 31P nuclear ...
Find patient medical information for Calcium Phosphate Tribasic Oral on WebMD including its uses, side effects and safety, ... Calcium Phosphate Tribasic Tablet. GENERIC NAME(S): Calcium Phosphate Tribasic. OTHER NAME(S): Calcium Phosphate Tribasic ... How to use Calcium Phosphate Tribasic Tablet. Take this medication by mouth with food. If your product contains calcium citrate ... certain phosphate binders (e.g., calcium acetate).. Calcium can decrease the absorption of other drugs such as bisphosphonates ...
Amorphous calcium phosphate, Tetra calcium phosphate, Biphasic calcium phosphate, Octa calcium phosphate and Forecast 2023 - ... Calcium Phosphate Market 2018 Size, Shares , Global Industry Revenue by Top Key Companies ? ... Amorphous calcium phosphate. • Tetra calcium phosphate. • Biphasic calcium phosphate. • Octa calcium phosphate. • Apatite. • ... Amorphous calcium phosphate, Tetra calcium phosphate, Biphasic calcium phosphate, Octa calcium phosphate and Forecast 2023. 11- ...
Said goal is achieved by producing the bone replacement material made of a mixture of calcium phosphate particles which is ... A resorbable bone replacement material made of calcium phosphate particles of different phases which are embedded in an ... calcium sulphate and different calcium phosphates. In the past, particularly calcium phosphates such as β-tricalcium phosphate ... The polyphenol oxidase and the polyphenols are dissolved preferably in phosphate buffer such as calcium phosphate or sodium ...
  • Synthesis of retinyl phosphate mannose and dolichyl phosphate mannose from endogenous and exogenous retinyl phosphate and dolichyl phosphate in microsomal fraction. (portlandpress.com)
  • The thermal treatment adopted in the synthesis of the calcium phosphate was limited to drying in the stove at temperature of 110 °C for 24 hours. (scielo.br)
  • In this study, a novel ultrasound-assisted sol-gel method was developed for the room-temperature synthesis of single-phase calcium silicate hydrate (C-S-H). The optimum synthesis conditions and the phosphate recovery properties of C-S-H were investigated by batch experiments. (rsc.org)
  • 4. The kit according to claim 3, wherein said lubricating medium is a sodium phosphate solution. (google.com)
  • The stability of ribose and lyxose improved after addition of 40-fold molar excess (relative to a pentose) of sodium silicate or sodium phosphate to the alkaline solution. (springer.com)
  • The stability was not improved further when an 80-fold molar excess of sodium silicate or sodium phosphate was added. (springer.com)
  • The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man. (jci.org)
  • The effects of insulin on the renal handling of sodium, potassium, calcium, and phosphate were studied in man while maintaining the blood glucose concentration at the fasting level by negative feedback servocontrol of a variable glucose infusion. (jci.org)
  • Deals in Animal feed, Sodium Hydroxide, Di Calcium Phosphate Feed Grade. (indianyellowpages.com)
  • ACP lacks the long-range, periodic atomic scale order of crystalline calcium phosphates. (wikipedia.org)
  • Overuse of certain forms of calcium phosphate can lead to nutrient -containing surface runoff and subsequent adverse effects upon receiving waters such as algal blooms and eutrophication . (wikipedia.org)
  • Numerous materials have been devised, as well as various forms of calcium phosphate, to act as supports, substitutes, or interfaces for repairing or replacing the naturally occurring structures. (google.com)
  • We knew for years that calcium phosphate-based materials promote osteogenic differentiation of stem cells, but none of us knew why," Varghese said. (redorbit.com)
  • The basic concept involves coating a thin layer of calcium phosphate onto the surface of highly porous ceramic material based on alumina, followed by Zn 2+ incorporation on the coating layer. (scielo.br)
  • This study covers the world outlook for monobasic calcium phosphates (minimum 21 percent P, 100 percent CaH4(PO4)2) across more than 190 countries. (reportlinker.com)
  • This study gives, however, my estimates for the worldwide latent demand, or the P.I.E., for monobasic calcium phosphates (minimum 21 percent P, 100 percent CaH4(PO4)2). (reportlinker.com)
  • In order to estimate the latent demand for monobasic calcium phosphates (minimum 21 percent P, 100 percent CaH4(PO4)2) on a worldwide basis, I used a multi-stage approach. (reportlinker.com)
  • To study and analyze the global Calcium Phosphate consumption (value & volume) by key regions/countries, product type and application, history data from 2013 to 2017, and forecast to 2023. (openpr.com)
  • Focuses on the key global Calcium Phosphate manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years. (openpr.com)
  • Factors such as wide acceptance of calcium phosphate, low product pricing, rising demand for healthy and nutritional food products, rise in orthopedic disorders, increasing use for calcium phosphate as diluents in drug formulations, and growing per capita and health care expenditure are likely to fuel the global calcium phosphate market. (transparencymarketresearch.com)
  • Other factors such as government initiative in conducting awareness programs, growing geriatric population, and rising application of calcium phosphate in the pharmaceutical industry, including dental, orthopedic, tissue regeneration, etc. are expected to further drive the global calcium phosphate market. (transparencymarketresearch.com)
  • The global calcium phosphate market can be segmented based on product type, end-user, and geography. (transparencymarketresearch.com)
  • In addition to calcium phosphate, the compositions include an effervescent agent to promote the formation of interconnected pores and a cohesiveness agent to maintain the shape. (google.es)
  • Most of us know that our bones and teeth are made primarily of calcium. (healthline.com)
  • Does this mean taking calcium phosphate supplements can give you healthier bones ? (healthline.com)
  • Calcium does more than build strong bones and healthy teeth . (healthline.com)
  • Phosphorus works with calcium to help build bones. (healthline.com)
  • Calcium phosphate is welcome in the body, when found in tooth enamel and bones. (ehow.co.uk)
  • If there is not enough calcium in the blood, then the body will take calcium from bones, thereby weakening bones. (webmd.com)
  • Having the right amount of calcium is important for building and keeping strong bones. (webmd.com)
  • Calcium is essential for development and maintenance of bones and teeth and for the proper function of the heart, muscles, nerves and other body systems. (livestrong.com)
  • Eating foods high in calcium and vitamin D plus exercise on a daily basis are important to maintaining healthy bones, according to the National Osteoporosis Foundation. (livestrong.com)
  • Development in biomedical sector such as nanomedicine, healing and preventing calcium deficiencies, lower the risk of colorectal cancer and well-built teeth and bones will enhance the industry growth. (fractovia.org)
  • I'm looking forward to two main benefits: reduced itchiness (which is happening, I don't use the creams anymore) and my bones recovering the calcium that has been leached from them over the last year. (globaldialysis.com)
  • any of a number of phosphates of calcium found in bones, teeth , etc. and used in medicine and in the manufacture of enamels , glass , cleaning agents , etc. (collinsdictionary.com)
  • Biological calcium phosphates are, with few exceptions, poorly or partly crystalline and impure, and sometimes comprise a mixture of phases. (springer.com)
  • Thus, the degree of static and dynamic disorder, the nature and location of substituents in a lattice, and larger-scale morphological differences such as crystal size, interlayering with non-calcium phosphate phases and crystal orientation, have all to be described. (springer.com)
  • The preparations were obtained from solutions with phosphate/pyrophosphate ratio, P/P2 = 7/3, and characterized as ACP using X-ray diffraction, infrared spectroscopy, nuclear magnetic resonance and differential thermal analysis. (scientific.net)
  • As routinely measured in the laboratory, the plasma calcium concentration includes all of the calcium in the plasma (free and bound). (uptodate.com)
  • In general, measuring the total plasma calcium concentration is sufficient since changes in this parameter are usually associated with parallel changes in the ionized concentration. (uptodate.com)
  • Due to its highly consistent pH and salt concentration, our CalPhos calcium phosphate transfection kit gives you the consistent transfection efficiency that you cannot always achieve with home brew versions. (clontech.com)
  • There was also a statistically significant but small reduction in plasma phosphate concentration which was not considered sufficient alone to account for the large reduction in UPV. (jci.org)
  • ii) injectable, ready-to-use organic-inorganic composites with partly elastomeric compression behavior were designed based on silk fibroin hydrogels and acidic calcium phosphates, and their ability for antibiotic drug delivery was assessed. (diva-portal.org)