Calcium metabolism disorders. Medical search

Disorders in the processing of calcium in the body: its absorption, transport, storage, and utilization.

Pathological conditions resulting from abnormal anabolism or catabolism of lipids in the body.

Disorders in the processing of phosphorus in the body: its absorption, transport, storage, and utilization.

Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)

Disorders in the processing of iron in the body: its absorption, transport, storage, and utilization. (From Mosby's Medical, Nursing, & Allied Health Dictionary, 4th ed)

Pathological conditions in which the BLOOD GLUCOSE cannot be maintained within the normal range, such as in HYPOGLYCEMIA and HYPERGLYCEMIA. Etiology of these disorders varies. Plasma glucose concentration is critical to survival for it is the predominant fuel for the CENTRAL NERVOUS SYSTEM.

Calcium compounds used as food supplements or in food to supply the body with calcium. Dietary calcium is needed during growth for bone development and for maintenance of skeletal integrity later in life to prevent osteoporosis.

A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.

Stable calcium atoms that have the same atomic number as the element calcium, but differ in atomic weight. Ca-42-44, 46, and 48 are stable calcium isotopes.

Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)

A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.

Abnormally high level of calcium in the blood.

A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.

Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.

The physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calcitriol increases intestinal absorption of calcium and phosphorus, and in concert with parathyroid hormone increases bone resorption.

A disease of pregnant and lactating cows and ewes leading to generalized paresis and death. The disease, which is characterized by hypocalcemia, occurs at or shortly after parturition in cows and within weeks before or after parturition in ewes.

A vitamin that includes both CHOLECALCIFEROLS and ERGOCALCIFEROLS, which have the common effect of preventing or curing RICKETS in animals. It can also be viewed as a hormone since it can be formed in SKIN by action of ULTRAVIOLET RAYS upon the precursors, 7-dehydrocholesterol and ERGOSTEROL, and acts on VITAMIN D RECEPTORS to regulate CALCIUM in opposition to PARATHYROID HORMONE.

Native, inorganic or fossilized organic substances having a definite chemical composition and formed by inorganic reactions. They may occur as individual crystals or may be disseminated in some other mineral or rock. (Grant & Hackh's Chemical Dictionary, 5th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Unstable isotopes of calcium that decay or disintegrate emitting radiation. Ca atoms with atomic weights 39, 41, 45, 47, 49, and 50 are radioactive calcium isotopes.

A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.

A class of G-protein-coupled receptors that react to varying extracellular CALCIUM levels. Calcium-sensing receptors in the PARATHYROID GLANDS play an important role in the maintenance of calcium HOMEOSTASIS by regulating the release of PARATHYROID HORMONE. They differ from INTRACELLULAR CALCIUM-SENSING PROTEINS which sense intracellular calcium levels.

Uptake of substances through the lining of the INTESTINES.

Hydroxy analogs of vitamin D 3; (CHOLECALCIFEROL); including CALCIFEDIOL; CALCITRIOL; and 24,25-DIHYDROXYVITAMIN D 3.

Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.

An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.

Two pairs of small oval-shaped glands located in the front and the base of the NECK and adjacent to the two lobes of THYROID GLAND. They secrete PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.

Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis.

A condition caused by a deficiency of PARATHYROID HORMONE (or PTH). It is characterized by HYPOCALCEMIA and hyperphosphatemia. Hypocalcemia leads to TETANY. The acquired form is due to removal or injuries to the PARATHYROID GLANDS. The congenital form is due to mutations of genes, such as TBX1; (see DIGEORGE SYNDROME); CASR encoding CALCIUM-SENSING RECEPTOR; or PTH encoding parathyroid hormone.

Cholecalciferols substituted with two hydroxy groups in any position.

I alpha-hydroxycholecalciferol: a treatment of renal bone disease. (1/44)

Three patients with chronic renal failure on maintenance haemodialysis have been treated with 1 alpha-hydroxycholecalciferol (1 alpha-OHCC), a synthetic vitamin D analogue. A daily dose of 2 mug by mouth produced a significant increase in both calcium absorption from the gastrointestinal tract and calcium content of bone. Treatment with 1 alpha-OHCC appears to be effective in cases of metabolic bone disease associated with chronic renal failure. (+info)

Idiopathic external root resorption associated to hypercalciuria. (2/44)

Although external root resorption (ERR) is a physiological process in deciduous dentition, it is very infrequent in permanent dentition - where the phenomenon is related to the existence of inadequate occlusal forces, periodontal pathology and microtraumatisms, etc. However, in many cases root resorption cannot be attributed to any concrete cause; such cases are defined as idiopathic external root resorption (IERR). Epidemiological studies have found that the underlying cause can only be established in 5% of all ERR. The present study describes three cases of IERR with different degrees of involvement and associated to mild calciuria and a history of nephrolithiasis. Hypercalciuria with normal blood calcium levels is usually idiopathic and exhibits a familial trait, with a prevalence of 20-40 cases per 1,000 individuals in adults. A form of hypercalciuria associated to nephrolithiasis with a mutation of the CLCN5 gene has been identified, involving low molecular weight proteinuria - though this mutation has not been uniformly demonstrated in most cases of idiopathic hypercalciuria. The peculiarity of the cases described in the present study is attributable to the coexistence of IERR with normocalcemic hypercalciuria and nephrolithiasis - thus pointing to the need for in-depth evaluation of the possible association of these three clinical situations. (+info)

Reduced bone mass in children with idiopathic hypercalciuria and in their asymptomatic mothers. (3/44)

BACKGROUND: Patients with nephrolithiasis and idiopathic hypercalciuria (IH) may exhibit reduced bone mineral density (BMD). Most studies measuring BMD in IH patients employing dual-energy X-ray absorptiometry (DEXA) have been performed in adults, and no study has been conducted in North-American children. Optimal bone mineral accretion during childhood and adolescence is critical to the attainment of a healthy adult skeleton. Bone mineral accretion and eventual adult peak bone mass are largely dependent on genetic factors. Hypercalciuria is also frequently linked to genetic determinants. Therefore, we carried out a cross-sectional evaluation of bone mineral metabolism in children with IH, and in their asymptomatic premenopausal mothers. METHODS: Quantitative BMD using DEXA was performed in 21 children with IH and in their asymptomatic mothers. Bone resorption was assessed by measuring the urinary concentrations of pyridinoline and deoxypiridinoline. Simultaneous calcium-modulating hormonal determinations, including serum intact immunoreactive parathyroid hormone and 1,25(OH)(2)D(3), were performed. The expression of interleukin-1alpha (IL-1alpha) by peripheral blood mononuclear cells (PBMCs) was determined by polymerase chain reaction. RESULTS: Reduced BMD values were observed in eight children (38%) and in seven mothers (33%). The children of osteopenic mothers exhibited significantly reduced BMD Z-score values of lumbar spine (P<0.05) when compared with children of mothers with normal BMD. Bone resorption markers were normal in most children with IH. Hypercalciuria was detected in five out of 20 (25%) asymptomatic mothers and it correlated (r=-0.81) to femoral BMD in mothers with osteopenia. The expression of IL-1alpha mRNA by PBMCs from IH children did not differ from controls. CONCLUSIONS: Reduced BMD was detected in a large proportion of children with IH. Hypercalciuria and reduced BMD were uncovered in a substantial number of their otherwise healthy asymptomatic mothers. The diminished BMD in adults with IH may start early in life, could be influenced by genetic factors, and may represent a risk factor for osteoporosis later in life. (+info)

Epithelial Ca(2+) channel (ECAC1) in autosomal dominant idiopathic hypercalciuria. (4/44)

BACKGROUND: The epithelial Ca(2+) channel (ECaC) exhibits the defining properties for being the gatekeeper in 1,25-dihydroxyvitamin D(3)-regulated Ca(2+) (re)absorption. Its recently cloned human orthologue (ECaC1) could, therefore, represent a crucial molecule in human disorders related to Ca(2+)-wasting such as idiopathic hypercalciuria (IH). METHODS: Fifty-seven members of nine families with IH were investigated. Phenotyping was performed by measurements of urinary Ca(2+) excretion, while other underlying disorders were appropriately excluded. Initially, the recently suggested locus for kidney stone-associated hypercalciuria on chromosome 1q23.3-q24 was investigated. Next, direct mutation analysis of all 15 exons of the ECAC1 gene and 2.9 kb upstream from the start codon was performed. hECaC1, heterologously expressed in human embryonic kidney 293 cells, was characterized by patch-clamp analysis. RESULTS: The mode of inheritance in the studied pedigrees is consistent with an autosomal dominant trait. Haplotype analysis did not implicate a role of the locus on chromosome 1. The coding sequence of the ECAC1 gene was not different between the affected and the non-affected family members. In the 5'-flanking region, three single nucleotide polymorphisms were encountered, but these polymorphisms were observed regardless of the affection status of the screened family members. Patch-clamp analysis of hECaC1 was performed as the putative pore region contains four non-conserved amino acid substitutions compared with the other species. This analysis revealed the distinctive properties of ECaC, including a high Ca(2+) selectivity, inward rectification, and Ca(2+)-dependent inactivation. CONCLUSION: These results do not support a primary role for hECaC1 in IH in nine affected families. Because of the heterogeneity of the disease, however, the involvement of ECaC1 in other subtypes of IH cannot be excluded and needs further investigation. The electrophysiological properties of hECaC1 further substantiate its prime role in Ca(2+) (re)absorption. (+info)

Urinary calcium excretion in children with vesicoureteral reflux. (5/44)

BACKGROUND: Renal malformations including vesico-ureteral reflux (VUR) are associated with urolithiasis. However, studies on urinary calcium excretion in children with VUR have not been reported. This study was conducted to find out whether children with VUR have a higher prevalence of hypercalciuria and whether their family members are affected by hypercalciuria and/or urolithiasis. METHODS: We studied the prevalence of hypercalciuria and urolithiasis in 46 children (12 males and 34 females) with VUR and in their parents. RESULTS: Three out of 46 children had renal colic and nine out of 46 exhibited calyceal microlithiasis in the renal sonography. According to Stapleton's criteria, we found that 27 out of 46 children (58.6%) had hypercalciuria. These children were significantly shorter than children with normal calciuria and showed lower values of maximal urinary osmolality. We found no differences in urinary calcium excretion values related to the VUR grading, or to the presence or absence of renal scars, or to whether VUR was still unresolved or already resolved at the time of study. Seventeen out of 27 children with hypercalciuria (63%) had one or both parents affected by hypercalciuria, and there was a history of urolithiasis in six first-degree relatives and in four second-degree relatives (37%). Besides, 10 out of 19 children without hypercalciuria (52.6%) had one or both parents affected by hypercalciuria and there was a history of urolithiasis in three first-degree relatives and in three second-degree relatives (31.6%). Among the 27 children whose parents had hypercalciuria, four had both parents affected, 19 had only the mother affected and in four patients only the father was affected. CONCLUSION: Our results showed that the prevalence of hypercalciuria was greater in paediatric patients with VUR than in the general population. Urolithiasis in patients with VUR had a metabolic origin. Hypercalciuria was inherited as an autosomal dominant trait although with a higher probability to be inherited from the mother. (+info)

Disruption of the caveolin-1 gene impairs renal calcium reabsorption and leads to hypercalciuria and urolithiasis. (6/44)

Using LoxP/Cre technology, we generated a knockout mouse homozygous for a null mutation in exon 2 of Cav1. In male Cav1-/- animals, we observed a dramatic increase in the incidence of urinary calcium stone formation. In 5-month-old male mice, the incidence of early urinary calculi was 67% in Cav1-/- mice compared to 19% in Cav1+/+ animals. Frank stone formation was observed in 13% of Cav1-/- males but was not seen in Cav1+/+ mice. Urine calcium concentration was significantly higher in Cav1-/- male mice compared to Cav1+/+ mice. In Cav1-/- mice, distal convoluted tubule cells were completely devoid of Cav1 and the localization of plasma membrane calcium ATPase was disrupted. Functional studies confirmed that active calcium absorption was significantly reduced in Cav1-/- compared to Cav1+/+ male mice. These results demonstrate that disruption of the Cav1 gene promotes the progressive steps required for urinary calcium stone formation and establish a new mouse model for urinary stone disease. (+info)

Quantitative trait loci for hypercalciuria in a rat model of kidney stone disease. (7/44)

Hypercalciuria is the most common risk factor for kidney stones and has a recognized familial component. The genetic hypercalciuric stone-forming (GHS) rat is an animal model that closely resembles human idiopathic hypercalciuria, with excessive intestinal calcium absorption, increased bone resorption, and impaired renal calcium reabsorption; overexpression of the vitamin D receptor (VDR) in target tissues; and calcium nephrolithiasis. For identifying genetic loci that contribute to hypercalciuria in the GHS rat, an F2 generation of 156 rats bred from GHS female rats and normocalciuric WKY male rats was studied. The calcium excretion was six- to eightfold higher in the GHS female than in the WKY male progenitors. Selective genotyping of those F2 rats with the highest 30% and lowest 30% rates of calcium excretion was performed, scoring 98 markers with a mean interval of 23 cM across all 20 autosomes and the X chromosome. With the use of strict criteria for significance, significant linkage was found between hypercalciuria and a region of chromosome 1 at D1Rat169 (LOD, 2.91). Suggestive linkage to regions of chromosomes 4, 7, 10, and 14 was found. The proportion of phenotypic variance contributed by the region on chromosome 1, with appropriate adjustments, was estimated to be 7%. Candidate genes encoding the VDR and the calcium-sensing receptor were localized to regions on rat chromosomes 7 and 11, respectively, but the suggestive quantitative trait locus on chromosome 7 was not in the region of the VDR gene locus. Identification of genes that contribute to hypercalciuria in this animal model should prove valuable in understanding idiopathic hypercalciuria and kidney stone disease in humans. (+info)

Hypercalciuria is a common and important finding in postmenopausal women with osteoporosis. (8/44)

OBJECTIVE AND DESIGN: The prevalence and the effects of hypercalciuria on bone in patients with primary osteoporosis are poorly defined. We therefore retrospectively analyzed the data of 241 otherwise healthy women. They were 45-88 years of age and had been referred for their first visit to our Unit for Metabolic Bone Diseases over a 2-year period because of primary osteoporosis (bone density T-score < -2.5). METHODS: The main parameters of calcium and skeletal metabolism had been analyzed in all subjects. This population was then divided into two groups, according to the presence (HC+) or absence (HC-) of hypercalciuria. RESULTS: Elevated urinary calcium was present in 19% of the subjects. Due to the selection criteria, spinal and femoral bone loss was similar in the two groups. Urinary calcium, phosphate and fractional calcium excretion were higher in hypercalciuric patients. In a logistic regression model, the higher the Tm of phosphate, the lower the risk of hypercalciuria (odds ratio 0.33, confidence interval 0.18-0.62). On the contrary, hypercalciuria was the most important predictor of low bone mass in HC+ (accounting for more than 50% of the variance in spinal bone density). CONCLUSIONS: Hypercalciuria is a common feature in postmenopausal bone loss. Since increased urinary calcium excretion and low bone mass appear to be linked, hypercalciuria seems to be an important determinant of reduced bone density in this setting as well. (+info)

... occur when the body has too little or too much calcium. The serum level of calcium is closely ... Disorders in calcium metabolism can lead to hypocalcemia, decreased plasma levels of calcium or hypercalcemia, elevated plasma ... and therefore levels of ionized calcium are better measures than a total calcium; however, one can correct a total calcium if ... A normal ionized calcium is 1.12-1.45 mmol/L (4.54-5.61 mg/dL). A normal total calcium is 2.2-2.6 mmol/L (9-10.5 mg/dl). Total ...

https://en.wikipedia.org/wiki/Disorders_of_calcium_metabolism

They were jointly the authors of Disorders of Calcium and Phosphate Metabolism in Childhood and Adolescence, a comprehensive ... Harrison, Harold E.; Harrison, Helen C. (1979). "Disorders of Calcium and Phosphate Metabolism in Childhood and Adolescence". ... and jointly published more than 175 research papers and one textbook on topics including pediatric metabolic disorders, ...

https://en.wikipedia.org/wiki/Harold_E._Harrison_and_Helen_C._Harrison

"Association of Level Oo GFR with Bone Disease And Disorders of Calcium And Phosphorus Metabolism". NKF K/DOQI Guidelines. ... PTH causes the release of calcium from the bones into the blood, and the reabsorption of calcium in the kidney. Thus, excess ... The symptoms of the disease are the consequences of both the general softening of the bones and the excess calcium in the blood ... ESRD occurs when the kidneys fail to produce calcitriol, a form of vitamin D, which assists in the absorption of calcium into ...

https://en.wikipedia.org/wiki/Osteitis_fibrosa_cystica

... s are also increasingly used in medicine to treat disorders associated with bone formation and calcium metabolism. ... Wiemer, AJ; Hohl, RJ; Wiemer, DF (June 2009). "The intermediate enzymes of isoprenoid metabolism as anticancer targets". Anti- ...

https://en.wikipedia.org/wiki/Phosphonate

"Parturient Paresis in Cows: Disorders of Calcium Metabolism: Merck Veterinary Manual". www.merckvetmanual.com. Retrieved 2015- ... In normal calcium regulation, a decrease in plasma calcium levels causes the parathyroid glands to secrete parathyroid hormone ... Intravenous calcium, though indicated in many cases, is potentially fatal through "heart blockade", or transient high calcium ... Treatment generally involves calcium injection by intravenous, intramuscular or subcutaneous routes. Before calcium injection ...

https://en.wikipedia.org/wiki/Milk_fever

His research interests broadened to include the study of clinical disorders of calcium and phosphorus metabolism, vitamin D ... In 1956 he was appointed Professor of Human Metabolism at UCH. In 1954 he was elected a Fellow of the Royal College of ... From 1946, his career focused on several inborn errors of metabolism. He was appointed a Commander of the Order of the British ... Charles Enrique Dent, CBE, FRCP, FRS (25 August 1911 - 19 September 1976) was a British professor of human metabolism at ...

https://en.wikipedia.org/wiki/Charles_Enrique_Dent

... stenosis or hypertrophic cardiomyopathy abnormal calcium-phosphorus metabolism Chronic kidney disease/ESRD genetic disorders ... Mitral annular calcification (MAC) is a multifactorial chronic degenerative process in which calcium with lipid is deposited ( ...

https://en.wikipedia.org/wiki/Mitral_annular_calcification

Molecular Genetics and Metabolism. 64 (3): 198-204. doi:10.1006/mgme.1998.2716. PMID 9719629. "Entrez Gene: CaSR calcium- ... Nemeth EF, Shoback D (Jun 2013). "Calcimimetic and calcilytic drugs for treating bone and mineral-related disorders". Best ... The calcium-sensing receptor (CaSR) is a Class C G-protein coupled receptor which senses extracellular levels of calcium ions. ... CASRdb - Calcium Sensing Receptor Database, McGill University Receptors,+Calcium-Sensing at the US National Library of Medicine ...

https://en.wikipedia.org/wiki/Calcium-sensing_receptor

Disorders of calcium metabolism DNA repair-deficiency disorders Glucose metabolism disorders Hyperlactatemia Iron metabolism ... disorders Lipid metabolism disorders Malabsorption syndromes Metabolic syndrome X Inborn error of metabolism Mitochondrial ... Hur, Kyu Yeon; Lee, Myung-Shik (2015-06-01). "Gut Microbiota and Metabolic Disorders". Diabetes & Metabolism Journal. 39 (3): ... Metabolic disorder screening can be done in newborns via blood, skin, or hearing tests. Metabolic disorders can be treatable by ...

https://en.wikipedia.org/wiki/Metabolic_disorder

His main research interests are the role of vitamin D and calcium nutrition in parathyroid disorders and bone health. He has ... He specializes in bone and mineral metabolism and endocrinology, specifically in hyperparathyroidism, osteomalacia, and bone ... Rao has contributed extensively to the broad field of bone & mineral metabolism. ...

https://en.wikipedia.org/wiki/D._Sudhaker_Rao

It is an inherited, autosomal recessive disorder due to a defective ryanodine receptor leading to huge calcium influx, muscle ... contracture and increase in metabolism. PSS can manifest itself in the abattoir as the production of Pale, Soft and Exudative ... This disorder is most common in Landrace, Piétrain and crossbreeds of these breeds of pig. The genes may have been favoured in ... This means that the disorder is rare in the developed world these days. Stress at slaughter should be minimised in all cases. ...

https://en.wikipedia.org/wiki/Porcine_stress_syndrome

... especially to the area of calcium metabolism. Albright made great strides and contributions to the understanding of disorders ... mainly into calcium metabolism and lead poisoning. He was subsequently assistant resident to Dr. Warfield Longcope at the Johns ... specifically the study of metabolism. After his internship at Massachusetts General Hospital he embarked on a one-year ... "extraordinarily original and monumental contributions to the understanding of metabolism of bone and other tissues." (1949) The ...

https://en.wikipedia.org/wiki/Fuller_Albright

The homozygous H63D variant is an indicator of the iron metabolism disorder hemochromatosis, which may increase the risk of ... and disturbances in the calcium channels in particular. ... Iron metabolism, Diseases and disorders, Single-nucleotide ... 2010). "Prevalent Iron Metabolism Gene Variants Associated with Increased Brain Ferritin Iron in Healthy Older Men". J. ... "H63D - The Other Mutation" (PDF). Iron Disorders Institute nanograms. 2010. Nandar W, Connor JR (2011). "HFE Gene Variants ...

https://en.wikipedia.org/wiki/HFE_H63D_gene_mutation

Regulation of calcium and phosphate metabolism by FGF23/Klotho]". Clinical Calcium. 19 (4): 523-8. PMID 19329831. Nabeshima Y ( ... Torbus-Paluszczak M, Bartman W, Adamczyk-Sowa M (2018). "Klotho protein in neurodegenerative disorders". Neurological Sciences ... van Goor MK, Hoenderop JG, van der Wijst J (2017). "TRP channels in calcium homeostasis: from hormonal control to structure- ... Wolf MT, An SW, Nie M, Bal MS, Huang CL (December 2014). "Klotho up-regulates renal calcium channel transient receptor ...

https://en.wikipedia.org/wiki/Klotho_(biology)

Lui S, Chu H (1943). "Studies in calcium and phosphorus metabolism with special reference to pathogenesis and effects of ... CKD-MBD is defined as a systemic disorder of mineral and bone metabolism due to CKD manifested by either one or a combination ... It is one measure of the skeletal component of the systemic disorder of chronic kidney disease-mineral and bone disorder (CKD- ... phosphate binders such as calcium carbonate, calcium acetate, sevelamer hydrochloride or carbonate, lanthanum carbonate, ...

https://en.wikipedia.org/wiki/Renal_osteodystrophy

... gastrointestinal disorders resulting in alterations of normal metabolism; use during pre-operative and postoperative periods in ... Equal or greater consideration should be given to diet, calcium balance, physiotherapy, and good general health promoting ... Because of the presence of its 17α-methyl group, the metabolism of stanozolol is sterically hindered, resulting in it being ... 1455-. ISBN 978-0-08-053960-7. Androgenic compounds rendered resistant to gastrointestinal and liver metabolism by containing ...

https://en.wikipedia.org/wiki/Stanozolol

Changes in mineral and bone metabolism that may cause 1) abnormalities of calcium, phosphorus (phosphate), parathyroid hormone ... CKD-mineral and bone disorders have been associated with poor outcomes. Metabolic acidosis may result from decreased capacity ... or vitamin D metabolism; 2) abnormalities in bone turnover, mineralization, volume, linear growth, or strength (kidney ...

https://en.wikipedia.org/wiki/Chronic_kidney_disease

Additional screens performed: - In-depth immunological phenotyping Disorders of calcium metabolism Parathyroid hormone family ... Hormonal Control of Calcium & Phosphate Metabolism & the Physiology of Bone". In Barrett KE, Barman SM, Boitano S, Brooks H ( ... PTH, Intact and Calcium Test Detail. Quest Diagnostics Lab. Accessed 2019-06-29. Parathyroid Hormone (PTH) Plus Calcium. ... The main determinant of the amount of calcium excreted into the urine per day is the plasma ionized calcium concentration ...

https://en.wikipedia.org/wiki/Parathyroid_hormone

Monitoring for other mineral metabolism disorders and the avoidance of invasive dental procedures for those who develop ... These include osteoporosis, high blood calcium due to cancer, bone breakdown due to cancer, Paget's disease of bone and ... Serious side effects may include kidney problems, low blood calcium, and osteonecrosis of the jaw. Use during pregnancy may ... Appropriate hydration is important before administration, as is adequate calcium and vitamin D intake before Aclasta therapy in ...

https://en.wikipedia.org/wiki/Zoledronic_acid

Clinical Endocrinology & Metabolism. 27 (3): 373-84. doi:10.1016/j.beem.2013.02.008. PMID 23856266. Kim JY, Ho H, Kim N, Liu J ... However, long term use of these causes resorption, degrading the bone to raise blood calcium. Consequently, these drugs have ... Nemeth EF, Shoback D (June 2013). "Calcimimetic and calcilytic drugs for treating bone and mineral-related disorders". Best ... April 2015). "Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma". ...

https://en.wikipedia.org/wiki/Calcilytic

In addition to estrogen, calcium metabolism plays a significant role in bone turnover, and deficiency of calcium and vitamin D ... due to decreased absorption of calcium in the stomach. Many diseases and disorders have been associated with osteoporosis. For ... In Parkinson's disease there may be a link between the loss of dopaminergic neurons and altered calcium metabolism (and iron ... Kerstetter JE, O'Brien KO, Insogna KL (2003). "Dietary protein, calcium metabolism, and skeletal homeostasis revisited". Am. J ...

https://en.wikipedia.org/wiki/Osteoporosis

Calcium metabolism Dent's disease Electrolyte disturbance Disorders of calcium metabolism Minisola, S; Pepe, J; Piemonte, S; ... controversy around the usefulness of corrected calcium as it may be no better than total calcium. Once calcium is confirmed to ... glucocorticoids increase urinary calcium excretion and decrease intestinal calcium absorption no effect on calcium level in ... Calcium deposits known as limbus sign may be visible in the eyes. Symptoms are more common at high calcium blood values (12.0 ...

https://en.wikipedia.org/wiki/Hypercalcaemia

PTH plays an important role in regulating blood calcium levels by raising the amount of calcium in the blood. Parathyroid ... BMC Endocrine Disorders. 7: 8. doi:10.1186/1472-6823-7-8. PMC 2099428. PMID 17916247. Khan, AR; James, MN (Apr 1998). " ... Clinical Cases in Mineral and Bone Metabolism. 7 (3): 207-240. PMC 3213842. Costa-Guda, J; Tokura, T; Roth, SI; Arnold, A (Oct ... 2010). "P12 - PTHC1: A Continuing Cell Line Expressing PTH and Genes Involved in Calcium Homeostasis". ...

https://en.wikipedia.org/wiki/Chief_cell

But his initial research was into amphibian metabolism, with his Ph.D. awarded in 1933 for 'Studies in the calcium metabolism ... 1981). Rehabilitation: including the role of disease, disorder and disability : the College of Medicine of South Africa Third ... Shapiro, H. A (1933). Studies in the calcium metabolism of the amphibian (Thesis). Place of publication not identified: [ ... guide 1 for Mju 400-K Studies in the calcium metabolism of the amphibian Symposium on enavid The frog pregnancy test : the ...

https://en.wikipedia.org/wiki/Hillel_Abbe_Shapiro

"The authors recommended a diet containing 1000 ppm potassium, 500 ppm calcium, 300 ppm magnesium and 50 ppm each of sodium, ... found that bees fed high-fructose corn syrup or sugar shows downregulation in several genes related to protein metabolism and ... "Colony Collapse Disorder Action Plan" (PDF). USDA. 20 June 2007. "CCD Steering Committee, Colony Collapse Disorder Progress ... US EPA (29 August 2013). "Colony Collapse Disorder". US EPA. Retrieved 10 December 2018. "Colony Collapse Disorder". sfyl.ifas. ...

https://en.wikipedia.org/wiki/Colony_collapse_disorder

The increase in appetite is coupled to alterations in nutrient metabolism due to the paracrine actions of agouti on adipose ... Hyperinsulinemia is caused by mutations to agouti, as the agouti protein functions in a calcium dependent manner to increase ... while certain polymorphisms of AgRP have been linked to eating disorders like anorexia nervosa. The mechanism underlying ... AgRP acts as an appetite stimulator and increases appetite while decreasing metabolism. Because of these mechanisms, AgRP may ...

https://en.wikipedia.org/wiki/Agouti-signaling_protein

Rosen, Clifford J. (2008-11-18). Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. John Wiley and Sons ... especially because of the internal biofeedback loop within the body with calcium inherently feeding back to calcium-receptors ... The remaining three glands are able to properly regulate serum calcium levels appropriately after the resolution of the ... hypercalcemia, as the calcium receptors lead to stimulation of parathyroid hormone secretion.[citation needed] "Parathyroid ...

https://en.wikipedia.org/wiki/Sestamibi_parathyroid_scan

... rare genetic disorders characterized by abnormal triglyceride metabolism), lipoid nephrosis, or acute pancreatitis if it is ... Dihydropyridine calcium channel blockers can produce negative inotropic effects and exacerbate heart failure. Heart failure ... Clevidipine (INN, trade name Cleviprex) is a dihydropyridine calcium channel blocker indicated for the reduction of blood ... Clevidipine is a dihydropyridine L-type calcium channel blocker, highly selective for vascular, as opposed to myocardial, ...

https://en.wikipedia.org/wiki/Clevidipine

Disorders of the Parathyroid Gland and Calcium Homeostasis". In Longo DL, Kasper DL, Jameson JL, Fauci AS, Hauser SL, Loscalzo ... The hormone participates in calcium (Ca2+) metabolism. In many ways, calcitonin counteracts parathyroid hormone (PTH) and ... In its skeleton-preserving actions, calcitonin protects against calcium loss from the skeleton during periods of calcium ... Calcitonin lowers blood calcium and phosphorus mainly through its inhibition of osteoclasts. Osteoblasts do not have calcitonin ...

https://en.wikipedia.org/wiki/Calcitonin

... metabolism such as hyperphosphatemia are included in the definition of the new chronic kidney disease-mineral and bone disorder ... Most people have no symptoms while others develop calcium deposits in the soft tissue. Often there is also low calcium levels ... Phosphate-binding medications include sevelamer, lanthanum carbonate, calcium carbonate, and calcium acetate. Previously ... "KDIGO Guideline for Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD)". Archived from the original on 4 March 2017. ...

https://en.wikipedia.org/wiki/Hyperphosphatemia

The brain is not able to switch to anaerobic metabolism and, because it does not have any long term energy stored, the levels ... Consequently, there is a massive influx of calcium into the cytosol, a massive release of glutamate from synaptic vesicles, ... Baldwin, Robert C. (2005). "Is vascular depression a distinct sub-type of depressive disorder? A review of causal evidence". ... Ischemia leads to alterations in brain metabolism, reduction in metabolic rates, and energy crisis. There are two types of ...

https://en.wikipedia.org/wiki/Brain_ischemia

In thermodynamic terms, metabolism maintains order by creating disorder. As the environments of most organisms are constantly ... About 99% of a human's body weight is made up of the elements carbon, nitrogen, calcium, sodium, chlorine, potassium, hydrogen ... Metabolism Look up metabolism in Wiktionary, the free dictionary. Wikimedia Commons has media related to Metabolism. General ... The metabolism of cancer cells is also different from the metabolism of normal cells, and these differences can be used to find ...

https://en.wikipedia.org/wiki/Metabolism

Fluoride has a high tendency to react with the calcium hydroxyapatite Ca10(PO4)6(OH)2 in tooth enamel due to its high affinity ... These processes contribute to reducing the risk of dental caries by inhibiting microbial metabolism in the tooth plaque. ... These fluorides in the brain may cause neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease and IQ ... For instance, calcium carbonate and magnesium carbonate are added as abrasives to remove dental plaque on teeth, while ...

https://en.wikipedia.org/wiki/Topical_fluoride

With respect to specific types of chemical damage caused by metabolism, it is suggested that damage to long-lived biopolymers, ... A set of rare hereditary (genetics) disorders, each called progeria, has been known for some time. Sufferers exhibit symptoms ... Williams suggested the following example: Perhaps a gene codes for calcium deposition in bones, which promotes juvenile ... People with diabetes, who have elevated blood sugar, develop senescence-associated disorders much earlier than the general ...

https://en.wikipedia.org/wiki/Senescence

Ikeda M, Ikui A, Komiyama A, Kobayashi D, Tanaka M (February 2008). "Causative factors of taste disorders in the elderly, and ... Prasad AS, Miale A, Farid Z, Sandstead HH, Schulert AR (April 1963). "Zinc metabolism in patients with the syndrome of iron ... "Effect of mercury vapour exposure on urinary excretion of calcium, zinc and copper: relationship to alterations in functional ... Low plasma zinc levels have been alleged to be associated with many psychological disorders. Schizophrenia has been linked to ...

https://en.wikipedia.org/wiki/Zinc_deficiency

Human iron metabolism Iron deficiency Hsu CC, Senussi NH, Fertrin KY, Kowdley KV (June 2022). "Iron overload disorders". ... skeletal: arthritis, from calcium pyrophosphate deposition in joints leading to joint pains. The most commonly affected joints ... Andrews, Nancy C. (1999). "Disorders of Iron Metabolism". New England Journal of Medicine. 341 (26): 1986-95. doi:10.1056/ ... metabolism: diabetes in people with iron overload occurs as a result of selective iron deposition in islet beta cells in the ...

https://en.wikipedia.org/wiki/Iron_overload

hypercalcemia (via calcium-sensing receptors) Gastrin release is inhibited by: the presence of acid (primarily the secreted HCl ... Clinical Endocrinology & Metabolism. 18 (4): 555-68. doi:10.1016/j.beem.2004.07.003. PMID 15533775. Anlauf M, Garbrecht N, ... This finding facilitates the diagnosis of patients with this neurogenetic disorder. Additionally, elevated gastrin levels may ... Dockray GJ (December 2004). "Clinical endocrinology and metabolism. Gastrin". Best Practice & Research. ...

https://en.wikipedia.org/wiki/Gastrin

Combined, these observations suggest that, as well as LDL cholesterol, disordered metabolism of triglyceride-rich lipoproteins ... Calcium cages, acid baths and recycling receptors". Nature. 388 (6643): 629-30. Bibcode:1997Natur.388..629B. doi:10.1038/41672 ... Additionally, each repeat has highly conserved acidic residues which it uses to coordinate a single calcium ion in an ... Both the disulfide bonds and calcium coordination are necessary for the structural integrity of the domain during the ...

https://en.wikipedia.org/wiki/LDL_receptor

... controls several developmental process and may regulate cellular processes like metabolism or learning. Calcium also plays a ... Foulquier F, Legrand D (October 2020). "Biometals and glycosylation in humans: Congenital disorders of glycosylation shed ... Calcium usually binds with other proteins and molecules in order to perform other functions in the body. The calcium bound ... A few (calcium, potassium, sodium) are present in relatively larger amounts, whereas most others are trace metals, present in ...

https://en.wikipedia.org/wiki/Biometal_(biology)

... and autism spectrum disorder (ASD). Environmental factors seem to promote deposition of iron in the vulnerable brain foci, and ... and calcium-ethylenediamine tetraacetate (CaEDTA). Pathological deposits of iron which occurs, e.g., in thalassemia can be ... Aaseth has studied the metabolism of copper and zinc, and the role of the tripeptide glutathione in the trafficking and ... Cerebral hypoperfusion in autism spectrum disorder. Acta Neurobiol Exp, 78(21), 9. Bjørklund, G., Skalny, A. V., Rahman, M. M ...

https://en.wikipedia.org/wiki/Jan_Aaseth

Its metabolism is highly stereoselective. Based on in vitro research, the major enzymes involved in the metabolism of doxepin ... Doxepin is used as a pill to treat major depressive disorder, anxiety disorders, and chronic hives, and for short-term help ... Bertelsen, Anne K.; Backonja, Misha-Miroslav (2007). "Drugs Targeting Voltage-Gated Sodium and Calcium Channels". Encyclopedia ... "Sleep Disorder (Sedative-Hypnotic) Drug Information - U.S. FDA". Food and Drug Administration. 13 June 2017. Retrieved 9 August ...

https://en.wikipedia.org/wiki/Doxepin

... the opening of calcium channels increasing in this way the cytosolic calcium concentrations. The lipophilic diacylglycerol ... Sugiyama H, Ito I, Hirono C (1987). "A new type of glutamate receptor linked to inositol phospholipid metabolism". Nature. 325 ... was effective in the treatment of generalized anxiety disorder. Also, some researchers have suggested that activation of mGluR4 ... They can also inhibit glutamate release and can modulate voltage-dependent calcium channels. Group I mGluRs, but not other ...

https://en.wikipedia.org/wiki/Metabotropic_glutamate_receptor

NMDA induces a calcium flux that allows for synaptic plasticity which is crucial for AHN. Researchers injected both ... a genetic disorder resulting in complete or partial insensitivity to androgens and a lack of external male genitalia. Neural ... Metabolism. 39 (2): 340-346. doi:10.1210/jcem-39-2-340. PMID 4278727. Scott F. Gilbert; with a chapter on plant development by ... The Journal of Clinical Endocrinology and Metabolism. 89 (10): 5245-55. doi:10.1210/jc.2004-0084. PMID 15472231. Vlahopoulos S ...

https://en.wikipedia.org/wiki/Androgen

"Balance Disorders". National Institute for Deafness and Other Communication Disorders (NIDCD). August 10, 2015. Archived from ... Within the labyrinth of the inner ear lie collections of calcium crystals known as otoconia or otoliths. In people with BPPV, ... Metabolism. 45 (3): 315-9. doi:10.1016/S0026-0495(96)90284-X. PMID 8606637. Huppert D, Strupp M, Mückter H, Brandt T (March ... BPPV is a type of balance disorder along with labyrinthitis and Ménière's disease. It can result from a head injury or simply ...

https://en.wikipedia.org/wiki/Benign_paroxysmal_positional_vertigo

Cannabis use disorder is defined in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) as ... It is important though to note that cannabinoids and other molecules present in cannabis can alter the metabolism of other ... The binding of cannabinoids to cannabinoid receptors decrease adenylyl cyclase activity, inhibit calcium N channels, and ... Cannabis use disorder is defined as a medical diagnosis in the fifth revision of the Diagnostic and Statistical Manual of ...

https://en.wikipedia.org/wiki/Effects_of_cannabis

... mutations as a result have been implicated in blood pressure disorders/diseases; a prime example being familial ... Cell Metabolism. 25 (2): 285-299. doi:10.1016/j.cmet.2017.01.007. PMID 28178566. Hadchouel J, Ellison DH, Gamba G (2016). " ... and large conductance calcium-activated potassium channel (BKCa) are the two primary channels for potassium secretion. WNK1 ...

https://en.wikipedia.org/wiki/WNK1

"Metabolism and Disposition of the Antihypertensive Agent Moxonidine in Humans". Drug Metabolism and Disposition. 31 (3): 334-42 ... It may have a role when thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or have ... It is contraindicated if there has been a past history of angioedema; heart conduction disorders (e.g. sick sinus syndrome, ...

https://en.wikipedia.org/wiki/Moxonidine

High supplemental calcium intake has been linked to advanced prostate cancer. Fish may lower prostate-cancer deaths, but does ... One of zinc's important roles is to change the cell's metabolism to produce citrate, an important semen component. The process ... "Androgens: Function, Measurement and Related Disorders". Cleveland Clinic. Retrieved 2022-04-28. "Prostate Cancer: Symptoms, ... Costello LC, Franklin RB (June 1998). "Novel role of zinc in the regulation of prostate citrate metabolism and its implications ...

https://en.wikipedia.org/wiki/Prostate_cancer

All vertebrates have a blood-brain barrier that allows metabolism inside the brain to operate differently from metabolism in ... Forrest, MD (2014). "Intracellular Calcium Dynamics Permit a Purkinje Neuron Model to Perform Toggle and Gain Computations Upon ... Brain-computer interface Central nervous system disease List of neuroscience databases Neurological disorder Optogenetics ... Glial cells play a major role in brain metabolism by controlling the chemical composition of the fluid that surrounds neurons, ...

https://en.wikipedia.org/wiki/Brain

Clinical Endocrinology & Metabolism. 30 (3): 413-30. doi:10.1016/j.beem.2016.06.004. PMID 27432075. Dungan K, Merrill J, Long C ... One comparison from 2014 found that a small dose of a calcium-channel blocker (such as amlodipine) may be used pre-operatively ... The National Organization for Rare Disorders is a United States-based advocacy parent organization with the goal of promoting ... Endocrinology & Metabolism. 3 (2): 92-102. doi:10.1038/ncpendmet0396. PMID 17237836. S2CID 23952363. Chen H, Sippel RS, ...

https://en.wikipedia.org/wiki/Pheochromocytoma

Reynolds CF, O'Hara R (October 2013). "DSM-5 sleep-wake disorders classification: overview for use in clinical practice". The ... It is frequently accompanied by calcium deposition and may have a microscopic papillary architecture. A computed tomography (CT ... Metabolism. 19 (2): 121-127. doi:10.1515/jpem.2006.19.2.121. PMID 16562584. S2CID 35451441. Porth CM (1990). Pathophysiology: ... The aim is simply to acknowledge the bidirectional and interactive effects between sleep disorders and coexisting medical and ...

https://en.wikipedia.org/wiki/Craniopharyngioma

... into Differential Drug Treatments for Hypoactive Sexual Desire Disorder and Female Sexual Arousal Disorder". The Journal of ... After metabolism, its metabolites are predominantly excreted via faeces. There are many types of drugs that unintentionally ... and calcium supplement pills daily. Gonadotropin-releasing hormone agonists are largely parenterally administered to the body, ... Turner, Daniel; Briken, Peer (January 2018). "Treatment of Paraphilic Disorders in Sexual Offenders or Men With a Risk of ...

https://en.wikipedia.org/wiki/Drugs_and_sexual_desire

Some EF-hand calcium binding proteins such as S100 or NCS-1 are also able to bind zinc ions. The U.S. Institute of Medicine ( ... It interacts with "a wide range of organic ligands", and has roles in the metabolism of RNA and DNA, signal transduction, and ... Prakash A, Bharti K, Majeed AB (April 2015). "Zinc: indications in brain disorders". Fundam Clin Pharmacol. 29 (2): 131-149. ... Krause J (2008). "SPECT and PET of the dopamine transporter in attention-deficit/hyperactivity disorder". Expert Rev. Neurother ...

https://en.wikipedia.org/wiki/Zinc_in_biology

... four gene areas overlapped with the five disorders, two of which regulate calcium balance in the brain. Environmental risk ... One study was able to differentiate 90% of cases of schizophrenia from controls based on hypoxia and metabolism. Hypoxia has ... attention deficit hyperactivity disorder, bipolar disorder, and major depressive disorder. One genome-wide association study ... Cross-Disorder Group of the Psychiatric Genomics Consortium (2013). "Identification of risk loci with shared effects on five ...

https://en.wikipedia.org/wiki/Risk_factors_of_schizophrenia

Children who do not consume the appropriate amount of calcium into their daily diets have lower calcium consumption as they get ... Metabolism. 24 (9): 431-441. doi:10.1016/j.tem.2013.05.005. PMC 3772345. PMID 23850261. Brown, Rebecca J.; De Banate, Mary Ann ... development of food preferences and eating disorders, digestive anatomy and functions, as well as brain development. Research ... A study of 9-year-old girls and calcium consumption reported those who met the average recommended intake (AI) for calcium ...

https://en.wikipedia.org/wiki/Sweetened_beverage

"X-linked recessive disorders." . GP notebook, n.d. Web. 4 Dec 2011. . "X-linked dominant disorders." . GP notebook, n.d. Web. 4 ... The lighter skin in females helps their bodies synthesize more Vitamin D from sunlight and absorb more calcium, which is needed ... "Gender Differences in Fat Metabolism". The University of New Mexico. Retrieved 22 August 2014. Legato, Marianne J. (2017). ... Women are more likely to suffer from unipolar depression, anxiety, eating disorders, and post-traumatic stress disorder. Men ...

https://en.wikipedia.org/wiki/Sex_differences_in_human_physiology

Amino acid metabolism disorders, X-linked recessive disorders, Syndromes affecting the eye, Syndromes affecting the kidneys). ... calcium and L-carnitine. This problem is known as Fanconi-type renal tubular dysfunction.[medical citation needed] This ... List of congenital disorders "Oculocerebrorenal Syndrome: Background, Pathophysiology, Epidemiology". 2016-06-01. {{cite ... Oculocerebrorenal syndrome (also called Lowe syndrome) is a rare X-linked recessive disorder characterized by congenital ...

https://en.wikipedia.org/wiki/Oculocerebrorenal_syndrome

For example, during the follicular phase, there is an increase in calcium, whereas there is an increase in magnesium during the ... The Journal of Clinical Endocrinology and Metabolism. 77 (5): 1215-1219. doi:10.1210/jcem.77.5.8077314. PMID 8077314. Wilcox, ... evidence that supports seed rotating between the phases of the menstrual cycle or the Moon directly impacts hormonal disorders ... Dullo, Puja; Vedi, Neeraj (July 2008). "Changes in serum calcium, magnesium and inorganic phosphorus levels during different ...

https://en.wikipedia.org/wiki/Seed_cycling

... and a lipid-soluble molecule that transports calcium ions (Ca2+) across the bilayer, also known as calcium ionophore. C1P was ... For instance, a study demonstrated a correlation between cellular drug resistance and modifications in GluCer metabolism. In ... immune function and neurodegenerative disorders. Glucosylceramides (GluCer) are the most widely distributed glycosphingolipids ... Inside the cell, S1P can induce calcium release independent of the S1PRs-the mechanism of which remains unknown. To date, the ...

https://en.wikipedia.org/wiki/Lipid_signaling

Calcium and magnesium in drinking water : public health significance World Health Organization (‎World Health ... "Calcium Metabolism Disorders". 0-9. A. B. C. D. E. F. G. H. I. J. K. L. M. N. O. P. Q. R. S. T. U. V. W. X. Y. Z. * 0-9 ...

https://apps.who.int/iris/browse?authority=Calcium+Metabolism+Disorders&type=mesh

https://extranet.who.int/iris/restricted/browse?locale-attribute=en&type=mesh&authority=Calcium+Metabolism+Disorders

Merck & Co., Inc., Rahway, NJ, USA (known as MSD outside of the US and Canada) is dedicated to using the power of leading-edge science to save and improve lives around the world. The Merck Veterinary Manual was first published in 1955 as a service to the community. The legacy of this great resource continues as the Merck Veterinary Manual in the US and Canada and the MSD Vet Manual outside of North America.. ...

https://www.merckvetmanual.com/multimedia/quiz/disorders-of-calcium-metabolism

Diagnosis is based on signs, serum calcium levels, and response to treatment. Slow intravenous administration of calcium ... Reducing stress and fasting during transport can help prevent the disorder. Pregnant mares should be fed adequate amounts and ... ratios of calcium and phosphorus throughout pregnancy to prevent lactation tetany. ...

https://www.msdvetmanual.com/en-au/metabolic-disorders/disorders-of-calcium-metabolism

Acromegaly is the same disorder of IGF-I excess but occurs after the growth plate cartilage fuses in adulthood. ... Disorders of calcium and bone metabolism. The following calcium and bone metabolism disorders can be found in acromegaly:. * ... Although gigantism is typically an isolated disorder, rare cases occur as a feature of other conditions, such as the following: ... For patient education information, the Thyroid & Metabolism Center, as well as, Acromegaly, Acromegaly FAQs, and Acromegaly ...

https://www.medscape.com/answers/925446-182290/which-therapies-are-used-in-the-treatment-of-gigantism-and-acromegaly

Disorders of calcium, phosphorus and magnesium metabolism. Journal of the Association of Physicians of India. 2008 Aug; 56(): ... calcium) or phosphorous metabolism. Several inherited disorders have been identified that result in renal or intestinal wasting ... Physicians need to have a thorough understanding of the mechanism of calcium, magnesium and phosphorous metabolism and ... Abnormalities of calcium, magnesium and phosphorus are common in hospitalized patients. Infrequently patients might present in ...

https://imsear.searo.who.int/handle/123456789/92042

"Calcium Metabolism Disorders" by people in this website by year, and whether "Calcium Metabolism Disorders" was a major or ... "Calcium Metabolism Disorders" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Calcium Metabolism Disorders*Calcium Metabolism Disorders. *Calcium Metabolism Disorder. *Disorder, Calcium Metabolism ... Below are the most recent publications written about "Calcium Metabolism Disorders" by people in Profiles. ...

https://profiles.ctsicn.org/display/24514

Results of search for su:{Calcium metabolism disorders.} Refine your search. *. Availability. * Limit to currently available ... Calcium disorders / edited by David Heath and Stephen J. Marx. by Heath, David , Marx, Stephen J. ... Calcium and magnesium in drinking water : public health significance. by World Health Organization. ... Calcium and magnesium in drinking water : beneficial impacts on health..Online access: Click here to access online Availability ...

https://kohahq.searo.who.int/cgi-bin/koha/opac-search.pl?q=su:%7BCalcium%20metabolism%20disorders.%7D

Calcium Metabolism Disorders. *Canker Sore. *Carpal Tunnel Syndrome. *Celiac Disease. *Cellulitis. *Chest Pain ...

https://www.healthgrades.com/physician/dr-katharine-price-xdy8p

Award winning parathyroid animation explains hyperparathyroidism and high calcium. Parathyroid tumor causes high calcium, ... Disorders of Calcium and Phosphorus Metabolism Here you will find some educational videos to help you to understand your ... Award winning parathyroid animation explains hyperparathyroidism and high calcium. Parathyroid tumor causes high calcium, ...

https://www.woendo.com/disorders-of-calcium-and-phosphorus-metabolism/

Disorders of calcium, glucose, or sodium metabolism. *Huntington disease (disorder that involves breakdown of nerve cells in ... Other movement disorders. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020: ... Antiphospholipid syndrome (disorder that involves abnormal blood clotting). *Benign hereditary chorea (a rare inherited ... Diagnosis and assessment of Parkinson disease and other movement disorders. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ ...

https://medlineplus.gov/ency/article/003196.htm

Calcium Metabolism Disorders ...

https://www.healthline.com/find-care/provider/dr-gilberto-vera-1982718383?utm_campaign=faq-profile&utm_content=profile-acceptingNewPatients

Elie Abed, MD is an Endocrinology, Diabetes & Metabolism Specialist in Tulsa, OK and has over 11 years of experience in the ... He suggested a sleep lab test first since sleep disorders are the most common cause. I was set-up to see a sleep specialist, ... Elie Abed, MD is an Endocrinology, Diabetes & Metabolism Specialist in Tulsa, OK and has over 11 years of experience in the ... Calcium Metabolism Disorders. *Celiac Disease. *Chronic Fatigue Syndrome. *Chronic Pain. *Constipation. *Diabetes Counseling ...

https://www.healthgrades.com/physician/dr-elie-abed-y9pdvpz

Calcium Metabolism Disorders. *Cancer Screening. *Candidiasis of Skin and Nails. *Canker Sore ...

https://www.healthgrades.com/physician/dr-philippe-chain-2d4sy

Other, less common, causes of elevated calcium include increased intake or absorption, granulomatous disease, immobilization, ... Hypercalcemia is a disorder that most commonly results from malignancy or primary hyperparathyroidism. ... Disorder of Calcium Metabolism. Alpern RJ, Moe OW, Caplan M, eds. Seldin and Giebischs The Kidney. 5th ed. Elsevier; 2013. ... Corrected total calcium (mg/dL) = (measured total calcium mg/dL) + 0.8 (for every decrement in the serum albumin of 1 g/dL ...

http://emedicine.medscape.com/article/766373

Categories: Calcium Metabolism Disorders Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...

https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Calcium+Metabolism+Disorders&parentid=16550&catid=5147

have a disorder related to calcium metabolism. *have perioral dermatitis (skin lesions around the mouth), ichthyosis (dry, ... there is a risk of developing high calcium levels in the blood. Your doctor may monitor your blood calcium levels regularly by ... High calcium in the blood: If this medication is used for severe psoriasis over a large area of skin or is used more than the ... symptoms of high blood calcium levels (e.g., constipation, depression, fatigue, loss of appetite, mental confusion, nausea, ...

https://www.medbroadcast.com/drug/getdrug/dovobet

Calcio urinario y anormalidad infantil.. Subject(s):. Calcium Metabolism, disordered. Journal Title Abbreviation:. Med. ibera. ... Lo que se sabe sobre absorción y eliminación del calcio y sobre las condiciones en que se encuentra en la sangre. ...

https://indexcat.nlm.nih.gov/vivisimo/cgi-bin/query-meta?&v:project=indexcat&sortby=Title&binning-state=serieVolume%3D%3DVolume%20003%0AserieNumber%3D%3DSeries%204,%201936-1948,%201955%0Alanguage%3D%3DSpanish%0AseriePage%3D%3DPage%2021&

Prognostic significance of disordered calcium metabolism in hormone-refractory prostate cancer patients with metastatic bone ...

https://pubmed.ncbi.nlm.nih.gov/?cmd=search&term=GORZEGNO+G%5Bau%5D&dispmax=50

Ayyoub frequently treats Hyperkalemia, Calcium Metabolism Disorders, and Kidney Transplant Evaluation. Where is Dr. Faten ... disordersHeart healthTransgender healthHepatitis CType 2 diabetesInflammationVaccinations and immunizationsLung cancerWeight ... disordersHeart healthTransgender healthHepatitis CType 2 diabetesInflammationVaccinations and immunizationsLung cancerWeight ...

https://www.sharecare.com/doctor/dr-faten-s-ayyoub

Genetics of monogenic disorders of calcium and bone metabolism. Newey, P. J., Hannan, F. M., Wilson, A. & Thakker, R. V., Oct ...

https://discovery.dundee.ac.uk/en/publications/?ordering=publicationYearThenTitle&descending=true&showAdvanced=false&allConcepts=true&inferConcepts=true&originalSearch=&improvedLayoutOrganisationUuid=&format=&page=16

E83.59 Other disorders of calcium metabolism E83.8 Other disorders of mineral metabolism ... E83.89 Other disorders of mineral metabolism E83.9 Disorder of mineral metabolism, unspecified ...

https://www.icd10data.com/ICD10CM/Codes/E00-E89/E70-E88/E84-/E84.19

She also sees patients for disorders of bone metabolism such as calcium disorders and osteoporosis. ... Patacsil specializes in endocrinology, diabetes and metabolism.. The main conditions she treats include: diabetes, thyroid ...

https://www.sanfordhealth.org/doctors/maria-patacsil

Thiazides may cause intermittent and slight elevation of serum calcium in the absence of known disorders of calcium metabolism ... Pharmacokinetics and Metabolism: Following oral administration of lisinopril, peak serum concentrations occur within about 7 ... Serum Uric Acid, Glucose, Magnesium, Cholesterol, Triglycerides and Calcium: (See PRECAUTIONS).. Hemoglobin and Hematocrit: ... Lisinopril does not undergo metabolism and is excreted unchanged entirely in the urine. Based on urinary recovery, the mean ...

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cd22026d-0250-4a53-93f0-1adf4e7f966b

Calcium Metabolism Disorders [C18.452.174]. *Hypercalcemia [C18.452.174.451]. *Water-Electrolyte Imbalance [C18.452.950] ... Interrelated role of Klotho and calcium-sensing receptor in parathyroid hormone synthesis and parathyroid hyperplasia. Proc ...

https://profiles.umassmed.edu/display/120364

A61P3/14-Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis ... 239000001506 calcium phosphate Substances 0.000 description 1 * 229910000389 calcium phosphate Inorganic materials 0.000 ... A61P5/00-Drugs for disorders of the endocrine system * A61P5/18-Drugs for disorders of the endocrine system of the parathyroid ... A61P19/00-Drugs for skeletal disorders * A61P19/08-Drugs for skeletal disorders for bone diseases, e.g. rachitism, Pagets ...

https://patents.google.com/patent/CN105055446B/en

This Metabolic Diseases Branch sees patients with disorders of calcium metabolism and metabolic bone disease, including ... studies bone and mineral disease with a focus on rare disorders of calcium and phosphate metabolism. ... Mineral Disorders Research is an endocrinologist interested in genetic disorders of bone and mineral metabolism particularly a ... Allison Boyce, Head, FD/MAS Studies Group, researches rare and congenital disorders of mineral metabolism, with a particular ...

https://www.niddk.nih.gov/research-funding/at-niddk/training-employment/medical-student-md/inter-institute-endocrinology-fellowship-program/fellowship-faculty-specialties

Welcome to our endocrinology practice where we specialize in the treatment of all endocrine disorders, including thyroid disorders and diabetes, as well as general endocrinology and metabolism problems. (hackensackmeridianhealth.org)
Dr. Schafer is Professor of Medicine and of Epidemiology & Biostatistics at UCSF and Chief of Endocrinology and Metabolism at the San Francisco VA Health Care System. (ucsf.edu)
Journal of Clinical Endocrinology and Metabolism. (elsevier.com)

Neonatal jaundice, neonatal cancer, inborn errors of metabolism, neonatal diabetes mellitus, neonatal herpes simplex, and neonatal seizure are a few of the more common problems a neonatologist will assist with. (drallencherer.net)

IMSEAR at SEARO: Disorders of calcium, phosphorus and magnesium metabolism. (who.int)
Abnormalities of calcium, magnesium and phosphorus are common in hospitalized patients. (who.int)
Infrequently patients might present in the outpatient settings with non-specific symptoms that might be due to abnormalities of divalent cation (magnesium, calcium) or phosphorous metabolism. (who.int)
Physicians need to have a thorough understanding of the mechanism of calcium, magnesium and phosphorous metabolism and diagnoses disorders due to excess or deficiency of these elements. (who.int)
Calcium and magnesium in drinking water : beneficial impacts on health. (who.int)
Inactive ingredients are dibasic calcium phosphate anhydrous, mannitol, corn starch, pre-gelatinized starch and magnesium stearate. (nih.gov)
In a fast-paced world, it's common to be low on important nutrients such as magnesium calcium vitamin D and other well-known vitamins. (antiaging-nutrition.com)
Magnesium plays an important role in many biochemical reactions, affecting blood pressure, metabolism, immune function, and many other activities in the body. (viproactive.de)
The mental disorder that researchers have linked to magnesium deficiency consists primarily of apathy and lack of emotion, although confusion and delirium sometimes occur. (viproactive.de)
It not only contains magnesium, but also other nutrients such as zinc, calcium, vitamin B6 and D, which together with Vitaprotein help you to get to the bottom of the magnesium deficiency. (viproactive.de)
The recommended intake of biotin is relatively low in comparison to some other nutrients, such as electrolytes (magnesium and calcium, for example) and vitamin C. This means that it can be easy to not only meet your needs, but to also exceed them. (draxe.com)

Menstrual Disorders (incl. (healthgrades.com)

Plasma calcium is maintained within the reference range by a complex interplay of 3 major hormones, parathyroid hormone (PTH), 1,25-dihydroxyvitamin D (ie, calcitriol), and calcitonin. (medscape.com)
Background: Hypoparathyroidism is an uncommon disorder of calcium metabolism characterized by hypocalcemia, hyperphosphatemia, and reduced level of parathyroid hormone (PTH). (endocrine-abstracts.org)
Calcium homeostasis refers to the hormonal regulation of serum ionized calcium by parathyroid hormone, 1,25-dihydroxyvitamin D, and serum ionized calcium itself, which together regulate calcium transport at the gut, kidney, and bone. (asnjournals.org)
These in turn are regulated by a set of interacting hormones, including parathyroid hormone (PTH), 1,25-dihydroxyvitamin D [1,25(OH) 2 D], ionized calcium itself, and their corresponding receptors in the gut, kidney, and bone. (asnjournals.org)
Calcium levels measured within 6 months of presentation were identified, and those with hypercalcemia (≥10.3 mg/dL) were reviewed if parathyroid hormone levels were measured. (bvsalud.org)
Patients were more likely to have parathyroid hormone levels sent if they were older, had higher calcium levels, or presented to an outpatient clinic (P = .028, P = .002, P (bvsalud.org)
Additionally, a substantial number of patients with nephrolithiasis did not have calcium and/or parathyroid hormone levels measured. (bvsalud.org)
Parathyroid hormone (PTH), calcium, phosphorus and urea measurements, as well as panoramic radiographs, were obtained from all patients. (bvsalud.org)

Published July 31, 2021 at 1002 × 662 in Calcium and Phosphate Metabolism and Related Disorders During Pregnancy and Lactation . (endotext.org)
Segawa H, Aranami F, Kaneko I, Tomoe Y, Miyamoto K. The roles of Na/Pi-II transporters in phosphate metabolism. (medscape.com)

Of the many attractive qualities of pediatric endocrinology, two in particular-its diversity of disorders and its intrinsically pediatric focus on growth and physical development-amplify the importance of practical knowledge of this specialty for the primary care provider. (mhmedical.com)

Award winning parathyroid animation explains hyperparathyroidism and high calcium. (woendo.com)
Hypercalcemia is a disorder that most commonly results from malignancy or primary hyperparathyroidism. (medscape.com)
In most primary hyperparathyroidism cases, the calcium elevation is caused by increased intestinal calcium absorption. (medscape.com)
This Metabolic Diseases Branch sees patients with disorders of calcium metabolism and metabolic bone disease, including sporadic and familial forms of primary hyperparathyroidism (e.g. (nih.gov)
With respect to bone alterations commonly observed in these individuals, bone metabolism disorders caused by altered blood levels of calcium (Ca) and phosphorus (P) in response to lack of activation of vitamin D by the kidneys promote the development of secondary hyperparathyroidism, contributing to alveolar bone loss by changing the normal skeletal remodeling, in addition to favoring the development of intra-osseous lesions such as brown tumor 14 . (bvsalud.org)

She also studies the relationships between bone, fat, and glucose metabolism, including the effects of obesity and diabetes on bone, and the skeletal regulation of energy metabolism. (ucsf.edu)
Bone-fat interplay-including the effects of fat on bone metabolism and the skeletal regulation of energy metabolism-is an area of increasing investigation. (ucsf.edu)
Vitamin B1 is important for energy metabolism and is found in meat, fish, poultry, whole grains, and lentils. (fellowmagazine.com)
Supports normal bone function and energy metabolism. (viproactive.de)

Pregnancy is characterized by physiologic changes in mineral metabolism, to allow calcium accretion in the fetal skeleton [ 1-3] . (who.int)
This brief review focuses on calcium balance and homeostasis and their relationship to dietary calcium intake and calcium supplementation in healthy subjects and patients with chronic kidney disease and mineral bone disorders (CKD-MBD). (asnjournals.org)
Because of the interdependent relationship between calcium and phosphorus for mineralization in bone and soft tissues, this review also discusses the interactions between calcium and phosphorus balance and homeostasis, the dysregulation that occurs in chronic kidney disease-mineral and bone disorders (CKD-MBD) ( 3 ), and the impact of calcium supplementation on phosphate homeostasis. (asnjournals.org)
Cod also contains selenium , an essential trace mineral which plays a key role in maintaining thyroid hormone metabolism. (readersdigest.ca)
Objective: To provide practical recommendations for the management of mineral and bone metabolism alterations in pregnancy and lactation. (bvsalud.org)
Participants: Members of the Working Group on Osteoporosis and Mineral Metabolism of the Spanish Society of Endocrinology and Nutrition. (bvsalud.org)

Hypercalcemic crisis does not have an exact definition, although marked elevation of serum calcium, usually more than 14 mg/dL, is associated with acute signs and symptoms of hypercalcemia. (medscape.com)
For hypercalcemia to develop, the normal calcium regulation system must be overwhelmed by an excess of PTH, calcitriol, some other serum factor that can mimic these hormones, or a huge calcium load. (medscape.com)
Hypercalcemia can result from a multitude of disorders. (medscape.com)
The main goal of treatment is to improve the symptoms of hypocalcemia, to keep the serum calcium within the low normal range, and to avoid hypercalcemia. (endocrine-abstracts.org)
a genetic metabolic disorder resulting from serum and bone alkaline phosphatase deficiency leading to hypercalcemia, ethanolamine phosphatemia, and ethanolamine phosphaturia. (icdlist.com)
the signs and symptoms vary significantly and include death in utero, failure to thrive, premature loss of deciduous teeth, early loss of the adult dentition, hypercalcemia, osteomalacia, skeletal defects, renal stones, and movement disorders. (icdlist.com)
Hypercalcemia and hypocalcemia indicate serious disruption of calcium homeostasis but do not reflect calcium balance on their own. (asnjournals.org)

However, there is increasing concern that many people, particularly older people, suffer from insufficient levels of vitamin D, with a 2012 study in the Journal of Clinical Endocrinology & Metabolism indicating 92.8% deficiency in its female, elderly subjects. (antiaging-nutrition.com)

She also sees patients for disorders of bone metabolism such as calcium disorders and osteoporosis. (sanfordhealth.org)
Dr. Masiukiewicz is a part time clinical faculty member at Yale University and has clinical interests in postmenopausal osteoporosis, disorders of calcium metabolism, metabolic bone disease and thyroid disease. (yale.edu)
Her research focus is osteoporosis and bone metabolism. (ucsf.edu)

Disorders in the processing of calcium in the body: its absorption, transport, storage, and utilization. (ctsicn.org)
Calcium balance refers to the state of the calcium body stores, primarily in bone, which are largely a function of dietary intake, intestinal absorption, renal excretion, and bone remodeling. (asnjournals.org)
Calcium requirement is dependent on the state of calcium metabolism, which is regulated by three main mechanisms: intestinal absorption, renal reabsorption, and bone turnover. (asnjournals.org)
Absorption and metabolism of a particular nutrient will be affected, to a greater or lesser degree, by the other nutrients available to the body. (organicready.org)
deferoxamine decreases levels of calcium carbonate by inhibition of GI absorption. (medscape.com)
Vitamin D is a fat-soluble vitamin that helps maintain strong bones and muscles, as well as promotes the absorption of calcium. (fellowmagazine.com)
Bioactive vitamin D, a fat-soluble steroid hormone, is vital for many essential bodily functions including the calcium and phosphorous absorption that helps maintain strong and healthy bones . (antiaging-nutrition.com)
Because vitamin D's active hormone, calcitriol, is particularly beneficial to bone health due to its role in aiding calcium and phosphorous absorption, a deficiency can lead to thin, brittle, misshapen bones, or the bone disease, osteomalacia (known as rickets in children). (antiaging-nutrition.com)

Glucose metabolism in the brain increases as a result of tasks that demand mental activity. (alchetron.com)

Several inherited disorders have been identified that result in renal or intestinal wasting of these elements. (who.int)
in turn, PTH is suppressed and renal calcium losses are increased. (endotext.org)
During lactation, the combined effects of PTHrP (secreted by the breast) and estrogen deficiency increase skeletal resorption, reduce renal calcium losses, and raise the blood calcium, but calcium is directed into breast milk. (endotext.org)
This becomes especially important in the setting of renal failure, when calcium levels drop and serum phosphate increases (this is why we give phosphate binders to patients with chronic kidney disease). (blueprintprep.com)
Prié D, Friedlander G. Genetic disorders of renal phosphate transport. (medscape.com)
Objetivou analisar a presença de hipertensão exploratorio, cuyo objetivo fue analizar la presencia arterial em pacientes portadores de doença renal crônica de hipertensión arterial en pacientes con enfermedad em tratamento hemodialítico e seus fatores associados. (bvsalud.org)

Aplicaciones clínicas del estudio del metabolismo del calcio. (nih.gov)
Nota sobre metabolismo del calcio. (nih.gov)
Trastornos del metabolismo del calcio en el organismo: su absorción, transporte, almacenamiento y utilización. (bvsalud.org)

resulting from lack of phosphate reabsorption by the kidneys and possible defects in vitamin d metabolism. (icdlist.com)
Serum testing of 1, 25-dihydroxyvitamin D levels may be considered medically necessary in the evaluation or treatment of conditions that are associated with defects in vitamin D metabolism. (exploremyplan.com)

These 3 hormones act primarily at bone, kidney, and small intestine sites to maintain appropriate calcium levels. (medscape.com)
individual hormones respond as needed to increase or decrease the serum calcium concentration. (medscape.com)
These are the organic compounds as well as microelements, indispensable amino acids, and fats, which, to a greater or lesser degree, regulate practically all processes in our body, from metabolism and producing hormones to forming tissues and generating energy. (vitaliv.us)
The insufficiency of these hormones, in turn, can slow down metabolism and lead to swelling, which prevents us from getting slim and losing weight. (vitaliv.us)
This is of major importance, as it triggers nerve activation in the case of transmitter substances, or controls metabolism in the case of hormones. (blogspot.com)
They make and regulate hormones that run the entire body's metabolism. (thyromate.com)

The Diabetes, Endocrine, and Obesity Branch conducts clinical and basic research in the area of diabetes, insulin resistance, thyroid physiology and pathology, metabolism, and body weight regulation. (nih.gov)

Comparison of the effects of acute estrogen deficiency vs. lactation on calcium and bone metabolism. (endotext.org)
Most often, those who are actively exercising experience a deficiency in vitamin B, vitamins A, E, and D, as well as calcium, copper, and potassium (the latter is actively washed out from our body with sweat). (vitaliv.us)
Finally, a deficiency in specific vitamins can block our attempts to lose weight, preventing our body from transforming accumulated fat into energy and slowing down our metabolism. (vitaliv.us)
If we get all essential vitamins and minerals, we are more energetic and feel less urge for unhealthy foods (as we don't have a deficiency in crucial substances), our metabolism is good at transforming calories into energy. (vitaliv.us)
Niacin deficiency can cause skin disorders such as acne or keratosis pilaris (chronic itchy bumps). (fellowmagazine.com)

Dr. Ayyoub frequently treats Hyperkalemia, Calcium Metabolism Disorders, and Kidney Transplant Evaluation. (sharecare.com)

In our body, Metabolic Disorders (Metabolic Diseases) , uasually associated as intestinal dis-orders , are caused by an abnormal metabolic process, including congenital due to inherited enzyme abnormalities or acquired due to a dis-ease of an endocrine organ or failure of a metabolically important organ. (wellnessadvocate.com)
Some patients with stomach problems may take it to combat acid reflux disease and some intestinal disorders. (dryseahorseforsale.com)
abametapir will increase the level or effect of clonazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
apalutamide will decrease the level or effect of clonazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)

Investigators study and treat patients with extreme insulin resistance, lipodystrophy, hypoglycemia, acromegaly and other disorders of carbohydrate and lipid metabolism. (nih.gov)

Dr. Patacsil specializes in endocrinology, diabetes and metabolism. (sanfordhealth.org)
She is board-certified in by the American Board of Internal Medicine in Internal Medicine and by the American Board of Internal Medicine in Endocrinology, Diabetes and Metabolism Subspecialty. (ucsf.edu)

Those suffering from an underactive thyroid can have many hypothyroidism symptoms associated with a slow metabolism including unexplained weight gain, hair loss, fatigue, depression, poor sleep, muscle weakness, and impaired memory. (thyromate.com)

Approximately 50% of calcium is bound to protein, primarily albumin, and the remaining 50% is ionized and is in physiologic active form. (medscape.com)
The thyroid hormone regulates energy and fat metabolism and protein synthesis by regulating different enzymes that are involved in those processes. (cdc.gov)
Vitamin K2 activates a protein hormone called osteocalcin, produced by osteoblasts, which is needed to bind calcium into the matrix of your bone. (organicready.org)
Neuroinflammatory markers, such as ionized calcium binding adaptor molecule 1 (Iba-1), glial fibrillary acidic protein (GFAP), gp91phox and inducible nitric oxide synthase (iNOS), were measured in the nigrostriatal system. (springer.com)
Despite the fact that there may not be a certain fertility-promoting diet program, consuming a assortment of healthful foods can assist prepare a woman's body for pregnancy by giving her sufficient shops of critical nutrients such as calcium, protein and iron. (wikidot.com)
Vitamin B6 is important for the metabolism of protein and carbohydrates, and the production of red blood cells and DNA. (fellowmagazine.com)
Diabetes mellitus is a metabolic disorder of multiple etiology, characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. (who.int)

To avoid calcium toxicity, the concentration of serum ionized calcium is tightly maintained within a physiologic range of 4.4 to 5.4 mg/dl (1.10 to 1.35 mM). (asnjournals.org)
Sakaee, The Effect of Diuretics on Ca Metabolism: Physiologic and Clinical Effects. (edu.au)

3.5 mmol/L) or ionized calcium of 10 mg/dL or greater (≥2.5 mmol/L) or that develops rapidly over days to weeks, can cause nausea, vomiting, dehydration, confusion, somnolence, and coma. (bvsalud.org)

Human genetic testing for diagnostic assessment of hereditary endocrine disorders. (labor-limbach.de)
Since an understanding of the clinical manifestations and treatments of endocrine disorders begins with knowledge of concepts of hormone action and principles of feedback control, the first chapter, "General Concepts and Physiology," links genetics, cell biology, and physiology with pathophysiology to provide a clear and approachable overview of endocrine systems. (mhmedical.com)

The patient, who received 6 gr calcitriol and 12 gr calcium carbonate treatment, was hospitalized with the diagnosis of resistant hypoparathyroidism. (endocrine-abstracts.org)

Human genetic testing for diagnostic assessment of hereditary disorders of the calcium/phosphate balance, lipid metabolism and iron metabolism. (labor-limbach.de)
Psoriasis is thought to be an autoimmune disorder (when the immune system attacks self), which affects people of any age, usually who have a genetic predisposition. (inhousepharmacy.vu)
For example, Dachshunds have dental genetic problems, so feeding them food with dental benefits and specific kibble size helps them with their genetic disorders. (isefmd.org)

This research program includes investigations of the effects of bariatric surgery (weight loss surgery) on calcium metabolism and skeletal health. (ucsf.edu)
Currently, she is studying the effects of bariatric surgery (surgical weight loss) on calcium metabolism and skeletal health. (ucsf.edu)
One of the most important functions as bound calcium is in skeletal mineralization. (asnjournals.org)
In bone, calcium serves two main purposes: it provides skeletal strength and, concurrently, provides a dynamic store to maintain the intra- and extracellular calcium pools. (asnjournals.org)

A loop diuretic (eg, furosemide) may be used with hydration to increase calcium excretion. (medscape.com)

High-potency B vitamins support metabolism, cellular, and nervous system health while Vitamin D and zinc support immune health. (allstarhealth.com)
Mean intake of calories, calcium, iron, zinc and vitamin A was assessed by using 24-hour recall method on subsample of 73 subjects and compared against the Ethiopian and African food composition tables. (bvsalud.org)
CONCLUSIONS: A significant proportion of women suffered from undernutrition and the mean intake of calories, calcium and zinc were below the recommended level for lactating women. (bvsalud.org)

The reference range of serum calcium levels varies among laboratories but generally is 8.7-10.4 mg/dL, with somewhat higher levels present in children. (medscape.com)
If the corrected serum calcium level still is not accurate, it is possible to measure the free calcium ion activity (ie, ionized calcium level). (medscape.com)
The patient was started on 2*20 mg teriparatide treatment, and daily serum calcium level control was performed. (endocrine-abstracts.org)
Serum calcium ranges from ∼8.8 to 10.4 mg/dl (2.2 to 2.6 mM) in healthy subjects. (asnjournals.org)
The main calcium-binding proteins include albumin and globulin in serum and calmodulin and other calcium-binding proteins in the cell. (asnjournals.org)

A study in the International Journal of Endocrinology found that having enough selenium in the body can prevent thyroid disorders like hyperthyroidism , which can cause increased metabolism, undesired weight loss, a fast or irregular heart rate, muscle weakness and changes in appetite. (readersdigest.ca)

99%) is present in the skeleton as calcium-phosphate complexes, primarily as hydroxyapatite, which is responsible for much of the material properties of bone ( 4 ). (asnjournals.org)
whereas vitamin D provides improved bone development by helping you absorb calcium, there is new evidence that vitamin K2 directs the calcium to your skeleton, while preventing it from being deposited where you don't want it - i.e., your organs, joint spaces, and arteries. (organicready.org)

Total calcium level decreases during pregnancy, due to hemodilution, while the ionized calcium level remains stable [2 ]. (who.int)
Maternal nutritional status may be an important factor in determining the extent to which PAE impacts pregnancy outcomes, particularly the dietary micronutrients folate and choline because they provide methyl groups for DNA methylation via one carbon metabolism. (bvsalud.org)
It reviews the diagnosis, evaluation, and management of the hypertensive disorders of pregnancy (HDPs), the prediction and prevention of preeclampsia, and the postpartum care of women with a previous HDP. (bvsalud.org)

As mentioned, a large part of arterial plaque consists of calcium deposits (atherosclerosis), hence the term "hardening of the arteries. (organicready.org)

In acromegaly, a severe disease that is often diagnosed late, morbidity and mortality rates are high, particularly as a result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. (medscape.com)
If the movements are due to a disease, the disorder should be treated. (medlineplus.gov)
Diagnosis and assessment of Parkinson disease and other movement disorders. (medlineplus.gov)
Importantly, increasing evidence suggests that calcium supplementation may enhance soft tissue calcification and cardiovascular disease in CKD-MBD. (asnjournals.org)
Those who have been chronically exposed to excessive amount of Mn can develop severe neurological disorders similar, but not identical, to the idiopathic Parkinson's disease. (cdc.gov)
To evaluate the oral conditions of patients with chronic kidney disease undergoing dialysis and to determine the influence of dialysis duration and bone metabolism on the prevalence and severity of the alterations found. (bvsalud.org)
Chronic kidney disease is directly related to cardiovascular disorders. (bvsalud.org)
however, immunocompromised immunocompromised A human or animal whose immunologic mechanism is deficient because of an immunodeficiency disorder or other disease or as the result of the administration of immunosuppressive drugs or radiation. (lecturio.com)
Parkinson's disease (PD) is a devastating neurodegenerative disorder characterized by progressive motor debilitation, which affects several million people worldwide. (springer.com)
Parkinson's disease (PD) is the most common neurodegenerative movement disorder, estimated to affect 1% of the population over 65 years of age. (springer.com)
Some studies have suggested vitamin B1 supplementation to treat Alzheimer's disease, Heart failure and Certain brain disorders common in people with alcoholism. (freefoodfacts.com)
Other than this, calcium is good on your properly-being and limits the gamble of disease, a dozing disorder, sluggishness, consciousness, and other scientific problems. (jimdosite.com)

El papel del calcio en el organismo. (nih.gov)

He also studies animal models to examine the regulation and role of G proteins in metabolism and hormone action. (nih.gov)
This brief review focuses on the key mechanisms in the gut, kidney, and bone involved in the regulation of calcium metabolism in humans. (asnjournals.org)
Bastepe M, Jüppner H. Inherited hypophosphatemic disorders in children and the evolving mechanisms of phosphate regulation. (medscape.com)

It is also used in the symptomatic treatment of inflammatory and allergic disorders and to suppress the immune system. (firedrug.com)
The health benefits of spirulina include strengthening the immune system, relieving inflammation, fighting chronic diseases, and prevent nutritional disorders. (jiji.ng)

Anatomy2

Diseases13

Chemicals and Drugs13

Phenomena and Processes2

I alpha-hydroxycholecalciferol: a treatment of renal bone disease. (1/44)

Idiopathic external root resorption associated to hypercalciuria. (2/44)

Reduced bone mass in children with idiopathic hypercalciuria and in their asymptomatic mothers. (3/44)

Epithelial Ca(2+) channel (ECAC1) in autosomal dominant idiopathic hypercalciuria. (4/44)

Urinary calcium excretion in children with vesicoureteral reflux. (5/44)

Disruption of the caveolin-1 gene impairs renal calcium reabsorption and leads to hypercalciuria and urolithiasis. (6/44)

Quantitative trait loci for hypercalciuria in a rat model of kidney stone disease. (7/44)

Hypercalciuria is a common and important finding in postmenopausal women with osteoporosis. (8/44)

Calcium Metabolism Disorders

Lipid Metabolism Disorders

Phosphorus Metabolism Disorders

Metabolic Diseases

Iron Metabolism Disorders

Glucose Metabolism Disorders

Calcium, Dietary

Calcium

Calcium Isotopes

Hypocalcemia

Bone and Bones

Parathyroid Hormone

Hypercalcemia

Phosphorus

Calcium Signaling

Calcitriol

Parturient Paresis

Vitamin D

Minerals

Calcium Radioisotopes

Hyperparathyroidism

Receptors, Calcium-Sensing

Intestinal Absorption

Hydroxycholecalciferols

Calcium Channels

Sarcoidosis

Parathyroid Glands

Osteomalacia

Hypoparathyroidism

Dihydroxycholecalciferols

I alpha-hydroxycholecalciferol: a treatment of renal bone disease. (1/44)

Idiopathic external root resorption associated to hypercalciuria. (2/44)

Reduced bone mass in children with idiopathic hypercalciuria and in their asymptomatic mothers. (3/44)

Epithelial Ca(2+) channel (ECAC1) in autosomal dominant idiopathic hypercalciuria. (4/44)

Urinary calcium excretion in children with vesicoureteral reflux. (5/44)

Disruption of the caveolin-1 gene impairs renal calcium reabsorption and leads to hypercalciuria and urolithiasis. (6/44)

Quantitative trait loci for hypercalciuria in a rat model of kidney stone disease. (7/44)

Hypercalciuria is a common and important finding in postmenopausal women with osteoporosis. (8/44)

Pathogenetic role of 1α,25-dihydroxyvitamin d in sarcoidosis and absorptive hypercalciuria: Different response to prednisolone...

Plus it

ENETS Abstract library

Calcium Metabolism and Bone Fractures. - Health Programs - Metabolic Energy

Regulation of calcium metabolism. - Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences

Absorptive hypercalciuria | definition of absorptive hypercalciuria by Medical dictionary

Idiopathic hypercalciuria in children - How valid are the existing diagnostic criteria?<...

Prevention of stone formation and bone loss in absorptive hypercalciuria by combined dietary and pharmacological interventions<...

Serum fat-soluble vitamin deficiency and abnormal calcium metabolism after malabsorptive bariatric surgery. - PubMed - NCBI

Increased urinary excretion of prostaglandin E in patients with idiopathic hypercalciuria | Clinical Science

Calcium metabolism | definition of calcium metabolism by Medical dictionary

Biochemical findings in sarcoidosis. | Journal of Clinical Pathology

What is the role of medications in the treatment of hypercalciuria in children?

European-North American Atrial Fibrillation Research Alliance (ENAFRA) | Leducq Foundation

Smiths Drugstore: Grapefruit instead of lipitor registered shipping!

Global Bone and Mineral Metabolism Disorders Treatment Market 2017- Merck＆Co.，Inc, Roche, Novartis, Warner Chilcott LLC, Sanofi...

Bioline International Official Site (site up-dated regularly)

Resolution of intracellular calcium metabolism in intact segments of rabbit aorta. | Circulation Research

A group of scientists studying calcium metabolism in : Critical Reasoning (CR)

What is the role of a 24-hour urinary calcium test in the workup of hypercalciuria?

2017/18 ICD-10-CM Diagnosis Code E83.50: Unspecified disorder of calcium metabolism

Pyruvate Metabolism Disorders - Pediatrics - Merck Manuals Professional Edition

L-Carnitine intake prevents irregular feeding-induced obesity and lipid metabolism disorder. | Sigma-Aldrich

Is hydrochlorothiazide-induced hypocalciuria due to inhibition of prostaglandin E2 synthesis? | Clinical Science | Portland...

IDIOPATHIC HYPERCALCIURIA (IH) | Kidney Stone Evaluation And Treatment Program

A Vogel - Calcium Absorption 400 Tabs

Dovobet Ointment - PrivateDoc®

NewYork-Presbyterian Queens - Disorders Affecting Calcium Metabolism

Overview of the Parathyroid Glands and Disorders of Calcium Metabolism - Endocrine System - Merck Veterinary Manual

NeoKe & Energy Metabolism Disorders - Solace Nutrition

Metabolism Disorders | Fremont Healthcare System

Calcium Metabolism in Renal Failure and Nephrolithiasis. | Annals of Internal Medicine | American College of Physicians

2011 ICD-9-CM Diagnosis Code 275.4 : Disorders of calcium metabolism

DI-fusion Bone and calcium metabolism in spinal cord injury

Possible Involvement of Brain Calcium Metabolism in the Action of Taurine in Mammalian Thermoregulation | SpringerLink

Health Article - Nutrition and Metabolism Disorders - AARP

Amino Acid Metabolism Disorders Related to Fatigue | Phoenix Rising ME / CFS Forums

Pediatric Metabolism Disorders | MaineHealth

Physiology of epithelial Ca2+ and Mg2+ transport

Prevalence and clinical characteristics of elevated 1-alpha,25-dihydroxyvitamin D in pediatric nephrolithiasis and related...

Ocular Pathology: Band Keratopathy

Control Your Salt for Fewer Stones and Stronger Bones | Kidney Stone Evaluation And Treatment Program