A calcium-binding protein that mediates calcium HOMEOSTASIS in KIDNEYS, BRAIN, and other tissues. It is found in well-defined populations of NEURONS and is involved in CALCIUM SIGNALING and NEURONAL PLASTICITY. It is regulated in some tissues by VITAMIN D.
Calcium-binding proteins that are found in DISTAL KIDNEY TUBULES, INTESTINES, BRAIN, and other tissues where they bind, buffer and transport cytoplasmic calcium. Calbindins possess a variable number of EF-HAND MOTIFS which contain calcium-binding sites. Some isoforms are regulated by VITAMIN D.
A calbindin protein found in many mammalian tissues, including the UTERUS, PLACENTA, BONE, PITUITARY GLAND, and KIDNEYS. In intestinal ENTEROCYTES it mediates intracellular calcium transport from apical to basolateral membranes via calcium binding at two EF-HAND MOTIFS. Expression is regulated in some tissues by VITAMIN D.
A calbindin protein that is differentially expressed in distinct populations of NEURONS throughout the vertebrate and invertebrate NERVOUS SYSTEM, and modulates intrinsic neuronal excitability and influences LONG-TERM POTENTIATION. It is also found in LUNG, TESTIS, OVARY, KIDNEY, and BREAST, and is expressed in many tumor types found in these tissues. It is often used as an immunohistochemical marker for MESOTHELIOMA.
Low molecular weight, calcium binding muscle proteins. Their physiological function is possibly related to the contractile process.
Agents, usually topical, that cause the contraction of tissues for the control of bleeding or secretions.
Proteins to which calcium ions are bound. They can act as transport proteins, regulator proteins, or activator proteins. They typically contain EF HAND MOTIFS.
The mucous lining of the LARYNX, consisting of various types of epithelial cells ranging from stratified squamous EPITHELIUM in the upper larynx to ciliated columnar epithelium in the rest of the larynx, mucous GOBLET CELLS, and glands containing both mucous and serous cells.
Secretagogins are EF HAND MOTIF-containing calcium-binding proteins that are involved in early neuronal migration and neurogenesis. They are also present in many adult organs and in brain and endocrine neoplasms.
Most generally any NEURONS which are not motor or sensory. Interneurons may also refer to neurons whose AXONS remain within a particular brain region in contrast to projection neurons, which have axons projecting to other brain regions.
Calcium-binding motifs composed of two helices (E and F) joined by a loop. Calcium is bound by the loop region. These motifs are found in many proteins that are regulated by calcium.
A bundle of NERVE FIBERS connecting each posterior horn of the spinal cord to the opposite side of the THALAMUS, carrying information about pain, temperature, and touch. It is one of two major routes by which afferent spinal NERVE FIBERS carrying sensations of somaesthesis are transmitted to the THALAMUS.
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
The physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calcitriol increases intestinal absorption of calcium and phosphorus, and in concert with parathyroid hormone increases bone resorption.
The output neurons of the cerebellar cortex.
Clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons. Sensory ganglia may also have intrinsic interneurons and non-neuronal supporting cells.
The number of CELLS of a specific kind, usually measured per unit volume or area of sample.
Transference of fetal tissue between individuals of the same species or between individuals of different species.
Several groups of nuclei in the thalamus that serve as the major relay centers for sensory impulses in the brain.
An enzyme that catalyzes the formation of acetylcholine from acetyl-CoA and choline. EC 2.3.1.6.
The portion of renal tubule that begins from the enlarged segment of the ascending limb of the LOOP OF HENLE. It reenters the KIDNEY CORTEX and forms the convoluted segments of the distal tubule.
Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.
NEURONS in the inner nuclear layer of the RETINA that synapse with both the RETINAL PHOTORECEPTOR CELLS and the RETINAL BIPOLAR CELLS, as well as other horizontal cells. The horizontal cells modulate the sensory signal.

Characterization of nodular neuronal heterotopia in children. (1/362)

Neuronal heterotopia are seen in various pathologies and are associated with intractable epilepsy. We examined brain tissue from four children with subcortical or periventricular nodular heterotopia of different aetiologies: one with severe epilepsy following focal brain trauma at 17 weeks gestation, one with hemimegalencephaly and intractable epilepsy, one with focal cortical dysplasia and intractable epilepsy, and one dysmorphic term infant with associated hydrocephalus and polymicrogyria. The connectivity of nodules was investigated using histological and carbocyanine dye (DiI) tracing techniques. DiI crystal placement adjacent to heterotopic nodules revealed numerous DiI-labelled fibres within a 2-3 mm radius of the crystals. Although we observed labelled fibres closely surrounding nodules, the majority did not penetrate them. Placement of DiI crystals within nodules also identified a limited number of projections out of the nodules and in one case there was evidence for connectivity between adjacent nodules. The cellular and neurochemical composition of nodules was also examined using immunohistochemistry for calretinin and neuropeptide Y (NPY), which are normally expressed in GABAergic cortical interneurons. Within heterotopic nodules from all cases, numerous calretinin-positive neurons were identified, along with a few cell bodies and many processes positive for NPY. Calretinin-positive neurons within nodules were less morphologically complex than those in the cortex, which may reflect incomplete differentiation into an inhibitory neuronal phenotype. There were also abnormal clusters of calretinin-positive cells in the overlying cortical plate, indicating that the migratory defect which produces heterotopic nodules also affects development of the cortex itself. Thus, heterotopic nodules consisting of multiple neuronal cell types are associated with malformation in the overlying cortical plate, and have limited connectivity with other brain regions. This abnormal development of connectivity may affect neuronal maturation and consequently the balance of excitation and inhibition in neuronal circuits, leading to their epileptogenic potential.  (+info)

Measurements of [Ca2+] using fura-2 in glioma C6 cells expressing calretinin with GFP as a marker of transfection: no Ca2+-buffering provided by calretinin. (2/362)

Glioma C6 cells were transfected with a plasmid containing the calretinin (CR) and green fluorescent protein (GFP) coding regions to analyze the effect of CR's presence on [Ca2+]i. Positive transfectants were identified by the detection of GFP and [Ca2+]i was measured using fura-2 as a probe. We found that neither the basic [Ca2+]i nor activated [Ca2+]i achieved by exposure to ionomycin, ADP or thapsigargin were affected by CR's presence in transfected cells, despite the ability of CR to bind Ca2+ as part of fusion protein. The level of expressed CR was estimated as at least 1 microM. The presented results suggest that CR's function is unlikely to be an intracellular Ca2+-buffer and support the hypothesis that CR might be involved in a specific Ca2+-dependent process. The results of this work also show that the S65T mutant of GFP is compatible with fura-2 measurements of intracellular [Ca2+]. We have demonstrated that the presence of GFP, as a transfection marker of glioma C6 cells, does not disturb fura-2 fluorescence, the basal or activated [Ca2+]i in these cells.  (+info)

Immunohistological studies of metabotropic glutamate receptor subtype 6-deficient mice show no abnormality of retinal cell organization and ganglion cell maturation. (3/362)

Immature retinal ganglion cells (RGCs) initially show a multistratified dendritic pattern, and, during the postnatal period, these dendrites gradually monostratify into ON and OFF sublaminae. The selective agonist of group III metabotropic glutamate receptors (mGluR), L-2-amino-4-phosphonobutyrate (L-AP-4), hyperpolarizes ON bipolar cells and reduces glutamate release. On the basis of L-AP-4-evoked inhibitory effects on ON-OFF segregation of developing RGCs, it has been hypothesized that glutamate-mediated synaptic activity is crucial for formation of the ON-OFF network. Gene-targeted ablation of mGluR6 specifically expressed in ON bipolar cells blocks normal ON responses but has been predicted to enhance glutamate release from ON bipolar cells. The mGluR6 knock-out mouse therefore provides a unique opportunity to investigate whether glutamate release and ON responses are important factors in the development of ON-OFF segregation. The combination of several different morphological analyses indicates that ON bipolar cells, as well as several distinct amacrine cells, in mGluR6 knock-out mice are normally distributed and correctly extend their terminals to defined retinal laminae. Importantly, both alpha and delta RGCs in adult mGluR6 knock-out mice are found monostratified into cell type-specific layers. Furthermore, no difference between wild-type and mGluR6 knock-out mice is observed in the maturation and dendritic stratification of developing RGCs. Hence, despite a deficit in normal ON responses, mGluR6 deficiency causes no abnormality in the retinal cellular organization nor in the stratifications of both ON bipolar cells and developing and mature RGCs. Based on these findings, we discuss several possible mechanisms that may underlie ON-OFF segregation of RGCs.  (+info)

Impaired motor coordination and Purkinje cell excitability in mice lacking calretinin. (4/362)

In the cerebellum, the parallel fiber-Purkinje cell synapse can undergo long-term synaptic plasticity suggested to underlie motor learning and resulting from variations in intracellular calcium concentration ([Ca2+]i). Ca2+ binding proteins are enriched in the cerebellum, but their role in information processing is not clear. Here, we show that mice deficient in calretinin (Cr-/-) are impaired in tests of motor coordination. An impairment in Ca2+ homeostasis in Cr-/- Purkinje cells was supported by the high Ca2+-saturation of calbindin-D28k in these cells. The firing behavior of Purkinje cells is severely affected in Cr-/- alert mice, with alterations of simple spike firing rate, complex spike duration, and simple spike pause. In contrast, in slices, transmission at parallel fiber- or climbing fiber-Purkinje cell synapses is unaltered, indicating that marked modifications of the firing behavior in vivo can be undetectable in slice. Thus, these results show that calretinin plays a major role at the network level in cerebellar physiology.  (+info)

Postnatal expression of calretinin-immunoreactivity in periodontal Ruffini endings in the rat incisor: a comparison with protein gene product 9.5 (PGP 9.5)-immunoreactivity. (5/362)

The postnatal expression of immunoreactivity for calretinin, one of the calcium binding proteins, and for protein gene product 9.5 (PGP 9.5), a general neuronal marker, was investigated in mechanoreceptive Ruffini endings in the periodontal ligament of the rat incisor. Age-related changes in the expression of these two proteins in periodontal nerves were further quantified with a computerized image analysis. At 1 day after birth, a few PGP 9.5-immunoreactive nerve fibers and a still smaller number of calretinin-positive fibers were found in the periodontal ligament: they were thin and beaded in appearance and no specialized nerve terminals were recognized. Tree-like terminals, reminiscent of immature Ruffini endings, were recognizable in 4-day-old rats by PGP 9.5-immunohistochemistry, while calretinin-immunostaining failed to reveal these specialized endings. At postnatal 7-11 days when PGP 9.5-immunostaining could demonstrate typical Ruffini endings, calretinin-immunopositive nerve fibers merely tapered off without forming the Ruffini type endings. A small number of Ruffini endings showing calretinin-immunoreactivity began to occur in the periodontal ligament at 24-26 days after birth when the occlusion of the first molars had been established. At the functional occlusion stage (60-80 days after birth), the Ruffini endings showing calretinin-immunoreactivity drastically increased in number and density, but less so than those positive for PGP 9.5-immunoreaction. The delayed expression of calretinin suggests that the function of the periodontal Ruffini endings is established after the completion of terminal formation because Ca2+, which binds to calcium binding proteins including calretinin with high affinity, plays an important role in mechano-electric transduction.  (+info)

Calretinin immunoreactive nerve endings in the trachea and bronchi of the rat. (6/362)

Nerve endings showing calretinin immunoreactivity were examined in the lower respiratory tract of the adult rat. Tree-like nerve endings were immunostained in the tracheal and bronchial smooth muscle layer. The endings that arose from thick nerve fibers and formed corpuscles composed of many arborized nerve terminals. A few of the nerve endings were also observed in the lamina propria of the tracheal mucosa, close to the epithelial layer. Immunoelectron microscopy revealed that the immunoreactive terminals were filled with mitochondria and scattered among the intermuscular collagen fibrils. Schwann cell sheath and collagen fibrils were intercalated between the smooth muscle cells and nerve endings. The calretinin immunoreactive nerve endings observed in the present study seem to be slowly adapting stretch receptors.  (+info)

Colchicine causes excessive ocular growth and myopia in chicks. (7/362)

Colchicine has been reported to destroy ganglion cells (GCs) in the retina of hatchling chicks. We tested whether colchicine influences normal ocular growth and form-deprivation myopia, and whether it affects cells other than GCs. Colchicine greatly increased axial length, equatorial diameter, eye weight, and myopic refractive error, while reducing corneal curvature. Colchicine caused DNA fragmentation in many GCs and some amacrine cells and photoreceptors, ultimately leading to the destruction of most GCs and particular sub-sets of amacrine cells. Colchicine-induced ocular growth may result from the destruction of amacrine cells that normally suppress ocular growth, and corneal flattening may result from the destruction of GCs whose central pathway normally plays a role in shaping the cornea.  (+info)

Math1: an essential gene for the generation of inner ear hair cells. (8/362)

The mammalian inner ear contains the cochlea and vestibular organs, which are responsible for hearing and balance, respectively. The epithelia of these sensory organs contain hair cells that function as mechanoreceptors to transduce sound and head motion. The molecular mechanisms underlying hair cell development and differentiation are poorly understood. Math1, a mouse homolog of the Drosophila proneural gene atonal, is expressed in inner ear sensory epithelia. Embryonic Math1-null mice failed to generate cochlear and vestibular hair cells. This gene is thus required for the genesis of hair cells.  (+info)

... is a protein that in humans is encoded by the CALB1 gene. It belongs to the calbindin family of calcium-binding ... "Entrez Gene: Calbindin 1". Retrieved 2018-10-04. Noble JW, Almalki R, Roe SM, Wagner A, Duman R, Atack JR (October 2018). "The ... Bauer MC, Nilsson H, Thulin E, Frohm B, Malm J, Linse S (April 2008). "Zn2+ binding to human calbindin D(28k) and the role of ... Tao L, Murphy ME, English AM (May 2002). "S-nitrosation of Ca(2+)-loaded and Ca(2+)-free recombinant calbindin D(28K) from ...
It is encoded in humans by the CALB2 gene and was formerly known as calbindin-D29k. S100G, formerly calbindin 3 and calbindin- ... Calbindin 1 or simply calbindin was first shown to be present in the intestine in birds and then found in the mammalian kidney ... Calbindins are three different calcium-binding proteins: calbindin, calretinin and S100G. They were originally described as ... and calbindin 1 has six. Unlike calbindin 1 and 2, S100G is a member of the S100 family of calcium-binding proteins. S100G ...
This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of ... Jeung EB, Krisinger J, Dann JL, Leung PC (Sep 1992). "Molecular cloning of the full-length cDNA encoding the human calbindin- ... 2004). "Control of differentiation-induced calbindin-D9k gene expression in Caco-2 cells by cdx-2 and HNF-1α". Am. J. Physiol. ... Howard A, Legon S, Spurr NK, Walters JR (1992). "Molecular cloning and chromosomal assignment of human calbindin-D9k". Biochem ...
"Entrez Gene: calbindin 2". Parmentier M, Passage E, Vassart G, Mattei MG (1991). "The human calbindin D28k (CALB1) and ... Expression was found in different neurons than that of the similar vitamin D-dependent calcium-binding protein, calbindin-28kDa ... Calretinin, also known as calbindin 2 (formerly 29 kDa calbindin), is a calcium-binding protein involved in calcium signaling. ... 16 (2): 118-24. doi:10.1097/PAP.0b013e31819923ce. PMID 19550372. S2CID 22438395. Winn B, Tavares R, Fanion J, Noble L, Gao J, ...
Calbindin Calmodulin Calsequestrin Kinjo, Tashi G; Schnetkamp, Paul PM. Ca2+ Chemistry, Storage and Transport in Biologic ... Compartmentalization of calcium binding proteins such as calretinin and calbindin-28 kDa has been noted within cells, ... calretinin and calbindin-28 kDa, in ganglion and amacrine cells of the rat retina". Molecular Vision. 14: 1600-1613. PMC ... Madame Curie Bioscience Database [Internet]. Retrieved 2 May 2016. Yáñez M, Gil-Longo J, Campos-Toimil M (2012). "Calcium ...
IMPA1 has been shown to interact with Bergmann glial S100B and calbindin. L-690,330 is a competitive inhibitor of IMPase ... Schmidt H, Schwaller B, Eilers J (April 2005). "Calbindin D28k targets myo-inositol monophosphatase in spines and dendrites of ... Berggard T, Szczepankiewicz O, Thulin E, Linse S (2003). "Myo-inositol monophosphatase is an activated target of calbindin D28k ... "Myo-inositol monophosphatase is an activated target of calbindin D28k". J. Biol. Chem. 277 (44): 41954-9. doi:10.1074/jbc. ...
"Calbindin 1, fibroblast growth factor 20, and alpha-synuclein in sporadic Parkinson's disease". Hum. Genet. 124 (1): 89-94. doi ... 2,4-dienoyl-CoA reductase 1 is a protein that in humans is encoded by the DECR1 gene. This gene encodes an accessory enzyme ... "Entrez Gene: 2,4-dienoyl-CoA reductase 1". Retrieved 2017-09-12. Alphey MS, Yu W, Byres E, Li D, Hunter WN (2005). "Structure ... Yu W, Chu X, Chen G, Li D (2005). "Studies of human mitochondrial 2,4-dienoyl-CoA reductase". Arch. Biochem. Biophys. 434 (1): ...
Vitamin D also increases transcription of genes that code for Calbindin. As the name implies, Calbindin functions as a calcium- ... Reddy and Katan recommend a salt intake below 5 g/day (5000 mg/day), and to increase potassium intake by 2 - 3 g/day. The study ... 2)Releases calcium from bones into the blood Vitamin D also plays a crucial role in maintaining serum calcium levels (Ca++ in ...
The VL is stained for calbindin and acetylcholinesterase. The axons ascend in the nucleus where they branch profusely. The VL ... François, C.; Yelnik, J.; Percheron, G.; Tandé, D. (1994). "Calbindin-D-28K as a marker of the associative coertical territory ... Part 2. Ch.21. pp. 1017-1061 diFiglia, M.; Pasik, P.; Pasik, T. (1982). "A Golgi and ultrastructural study of the monkey globus ... 3.0.co;2-i. PMID 10660885. Sato, F.; Parent, M.; Levesque, M.; Parent, A. (2000). "Axonal branching patterns of neurons of ...
Those in the upper layer (or dorsal tier) contain a binding protein called calbindin-D28K which can buffer calcium levels ... Nemoto, C.; Hida, T.; Arai, R. (1999-10-30). "Calretinin and calbindin-D28k in dopaminergic neurons of the rat midbrain: a ... "Calbindin content and differential vulnerability of midbrain efferent dopaminergic neurons in macaques". Frontiers in ... 29 (2): 444-453. doi:10.1523/JNEUROSCI.4029-08.2009. ISSN 1529-2401. PMC 6664950. PMID 19144844. Prensa, L.; Parent, A. (2001- ...
"Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene". FASEB J. ... 13 (2): 115-7. doi:10.1016/j.cmet.2011.01.011. PMID 21284975. Ng S.F., Lin R.C., Laybutt D.R., Barres R., Owens J.A., Morris M. ... 128 (2 Suppl): 401S-406S. doi:10.1093/jn/128.2.401S. PMID 9478036. Mehedint MG, Niculescu MD, Craciunescu CN, Zeisel SH (Jan ... 65 (2): 88-94. doi:10.1111/j.1753-4887.2007.tb00285.x. PMID 17345961. Martin JF; Johnston CR; Han CT; Benyshek DC (April 2000 ...
Calcium influx from the diet and its subsequent binding to calbindin-D9k could be the rate-limiting step that modulates vitamin ... Koo TH, Yang H, Jeung EB (2011-07-01). "Expression of Calcium Transport Genes in the Placenta of Calbindin-D9k and -D28k ... TRPV6 is known to co-localize with TRPV5 Calbindin-D28K in apical domains of distal convoluted tubules and connecting tubules [ ... In many rodent lines, genetic variations in TRPV6, calbindin-D9k, PMCA1b mRNA influence intestinal Ca absorption and its impact ...
A specific, recognizable feature of Purkinje neurons is the expression of calbindin. Calbindin staining of rat brain after ... Whitney ER, Kemper TL, Rosene DL, Bauman ML, Blatt GJ (February 2008). "Calbindin-D28k is a more reliable marker of human ... Retrieved 2 February 2015. Horvath S, Mah V, Lu AT, Woo JS, Choi OW, Jasinska AJ, Riancho JA, Tung S, Coles NS, Braun J, ... 129 (Pt 2): 290-2. doi:10.1093/brain/awh729. PMID 16434422. Fine EJ, Ionita CC, Lohr L (December 2002). "The history of the ...
Other calcium-binding protein markers are calretinin (most abundant subtype in DLPFC, about 50%) and calbindin. Interneurons ... calbindin D-28k or parvalbumin in monkey prefrontal cortex: distribution and morphology". The Journal of Comparative Neurology ... the role of the calcium-binding proteins calbindin D-28k, calretinin and parvalbumin, in cerebellar physiology. Studies with ... 63 (2): 437-48. doi:10.1016/j.molimm.2014.09.019. PMID 25451973. Fernandes TJ, Costa J, Carrapatoso I, Oliveira MB, Mafra I ( ...
However, calbindin and calretinin also show low levels of staining in the ventral nuclear group and in the medial and lateral ... A given region usually stains for two of the three proteins-parvalbumin, calbindin, and calretinin The neurons comprising the ... Moderate amounts of parvalbumin staining are also present in regions of the medio-dorsal nucleus (MD). By contrast, calbindin ... The primate thalamus consists of a matrix of calbindin immunoreactive cells and a superimposed core of parvalbumin ...
Viena, Tatiana D.; Rasch, Gabriela E.; Silva, Daniela; Allen, Timothy A. (2021). "Calretinin and calbindin architecture of the ... 480 (2): 115-142. doi:10.1002/cne.20342. PMID 15514932. S2CID 9284778. Wouterlood, F. G.; Saldana, E.; Witter, M. P. (1990). " ... 296 (2): 179-203. doi:10.1002/cne.902960202. PMID 2358531. S2CID 24568442. Vertes, R. P. (2006). "Interactions among the medial ...
... calbindin expressed in distal tubules and aquaporin 2 expressed in the collecting duct cells. The mammalian kidney develops ... 2:23) state that God searches out and inspects the kidneys, or "reins", of humans, together with the heart. The kidneys, like ... 5 (2/3): 70-83. doi:10.4024/230503.jbpc.05.02. Maton A, Hopkins J, McLaughlin CW, Johnson S, Warner MQ, LaHart D, Wright JD ( ... 8 (Suppl 2): S102-S108. doi:10.1007/978-1-59745-016-4_16. ISBN 978-1-58829-081-6. PMC 4869439. Gaitonde DY (15 December 2017 ...
... and calbindin. A small number of HSD2 neurons (less than 2%) may express the neuropeptide galanin. Their lack of expression of ... 497 (2): 223-50. doi:10.1002/cne.20993. PMID 16705681. Shin, JW; Geerling, JC; Loewy, AD (Dec 10, 2008). "Inputs to the ... 26 (2): 411-7. doi:10.1523/JNEUROSCI.3115-05.2006. PMC 6674421. PMID 16407537. Geerling, JC; Loewy, AD (Oct 18, 2006). " ... 93 (2): 177-209. doi:10.1113/expphysiol.2007.039891. PMID 17981930. Geerling, JC; Loewy, AD (Mar 2007). "Sodium depletion ...
Calbindin is expressed by cerebellar Purkinje cells and granule cells of the hippocampus. The reorganization and migration of ... calbindin-stained Purkinje neurons in rat cerebellum after peripheral nerve injury suggests that calbindin may be a marker for ... Microtubule-associated protein 2 (MAP-2) is a cytoskeletal protein. Its expression is weak in neuronal precursors but it ... 63 (2): 378-383. Bibcode:1969PNAS...63..378G. doi:10.1073/pnas.63.2.378. PMC 223575. PMID 4895535. Islam, M (2007). "In situ ...
... calbindin -calcitonin - calcitonin gene-related peptide - calcitonin gene-related peptide receptor - calcitonin receptor - ... Articles related to biochemistry include: Contents: Top 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 2-amino-5- ... Bcl-2 - bcr-abl fusion protein - benzene - benzene ring - beta-2 microglobulin - beta adrenergic receptor - beta sheet - beta-1 ... leucine-2-alanine enkephalin - leukotriene B4 receptor - LH - LH receptor - LHRH receptor - life - life form - ligand - light ...
Lutz W, Frank EM, Craig TA, Thompson R, Venters RA, Kojetin D, Cavanagh J, Kumar R (2003). "Calbindin D28K interacts with Ran- ... 2: 28. doi:10.1186/1471-2407-2-28. PMC 137593. PMID 12421467. Ideguchi H, Ueda A, Tanaka M, Yang J, Tsuji T, Ohno S, Hagiwara E ... 272 (1-2): 25-33. doi:10.1016/S0378-1119(01)00553-4. PMID 11470507. Caballero OL, Resto V, Patturajan M, Meerzaman D, Guo MZ, ... 2: 28. doi:10.1186/1471-2407-2-28. PMC 137593. PMID 12421467. Hafizi S, Alindri F, Karlsson R, Dahlbäck B (2003). "Interaction ...
Woo TU, Shrestha K, Lamb D, Minns MM, Benes FM (April 2008). "N-Methyl-D-Aspartate Receptor and Calbindin-Containing Neurons in ... calbindin, targeting the dendrites of pyramidal neurons, and the expression of the mRNA for the GluR5 kainate receptor in GABA ... 13 (2): 623-31. doi:10.1523/JNEUROSCI.13-02-00623.1993. PMC 6576661. PMID 8093901. Manev H, Favaron M, Guidotti A, Costa E ( ... J. 173 (2): 278-86. doi:10.1016/j.tvjl.2005.11.007. PMID 16376594. Kinnamon SC, Vandenbeuch A (July 2009). "Receptors and ...
The latter group is represented by calbindin D9k and these proteins do not undergo calcium dependent conformational changes. ... and Ca2+ buffers such as calreticulin and calbindin D9k. While the majority of the known EF-hand calcium-binding proteins ( ... 269 (2): 454-6. doi:10.1016/0014-5793(90)81214-9. PMID 2401372. Finn BE, Forsén S (January 1995). "The evolving model of ... 11 (2): 198-205. doi:10.1110/ps.33302. PMC 2373453. PMID 11790829. Eukaryotic Linear Motif resource motif class LIG_EH_1 ...
These cells, which show intense immunoreactivity for calbindin and calretinin, are characterized by their large size and axonal ... 3.0.CO;2-X. PMID 9699912. Neuronal Migration and Formation of Cellular Patterns During Brain Development - from the site of the ...
... s express somatostatin and sometimes calbindin, but not parvalbumin or vasoactive intestinal peptide. ... 15 (2): e2001392. doi:10.1371/journal.pbio.2001392. ISSN 1545-7885. PMC 5300109. PMID 28182735. Riedemann, T (17 June 2019). " ...
Calbindin is a protein involved in calcium ion transport within cells, and excess calcium in cells is toxic. The calbindin ... Secondly, dopaminergic neurons in the pars compacta contain less calbindin than other dopaminergic neurons. ... "Midbrain dopaminergic neurons in the mouse that contain calbindin-D28k exhibit reduced vulnerability to MPTP-induced ... 3.0.CO;2-E. PMID 10649295. Lima MM, Andersen ML, Reksidler AB, Vital MA, Tufik S (June 2007). Brosnan S (ed.). "The role of the ...
In the rat, few also express calbindin (CB) or calretinin (CR). Many of the DTN GABAergic cells do express parvalbumin (PV) ... 16 (2): 117-33. doi:10.1016/s0891-0618(98)00063-5. PMID 10223311. S2CID 916774. Hayakawa T, Zyo K (1991). "Quantitative and ... 630 (1-2): 188-94. doi:10.1016/0006-8993(93)90656-8. PMID 8118685. S2CID 25282593. Dillingham CM, Holmes JD, Wright NF, ...
However, some reports have indicated that Renshaw cells synthesize calcium-binding proteins calbindin-D28k and parvalbumin.[ ... 197 (2): 83-97. doi:10.1111/j.1748-1716.2009.02020.x. PMID 19673737. Hultborn H (2006). "Spinal reflexes, mechanisms and ... 342 (2): 221-31. doi:10.1002/cne.903420206. PMID 8201033. Goshgarian, HG (2003). Neuroanatomic Organization of the Spinal Gray ... V0 neurons are commissural neurons that extend their axons rostrally for 2-4 spinal cord regions in the embryonic spinal cord. ...
The territory is stained for calbindin. The mediator of the pallido-thalamic connection is the inhibitor GABA. The ... Retinal axons from the controlateral retina end in stratae 1,4 and 6. Those from the ipsilateral retina end in 2,3 and 5. The ... Friedman, Jones E.G. (1986). "Thalamic input to area 3a and 2 in monkeys". J. Neurophysiol. 45 (59): 85. Kaas J.H., Nelson R.J ... 4 (2): 539-560. doi:10.1523/JNEUROSCI.04-02-00539.1984. PMC 6564912. PMID 6199485. Orioli, P.J.; Strick, P.L. (1989). " ...
... and calbindin (25%) and resembles alpha-parvalbumin in its N-terminal region (52%). It has a 40-residue N-terminal domain with ... Oncomodulin 2 Yin; et al. (June 2006). "Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion ...
VTA neurons are protective against MPP+ insult due to the expression of calbindin. Calbindin regulates the availability of Ca2+ ... 2 (1): 141-151. doi:10.1038/nprot.2006.342. PMID 17401348. S2CID 39743261. "Pesticides and Parkinson's Disease - A Critical ... 2-Phenyl- and 2-Phenylalkyl-Piperidines". Journal of Organic Chemistry. 12 (6): 885-893. doi:10.1021/jo01170a021. PMID 18919741 ... "1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine". ChemIDplus. Frim, D. M.; Uhler, T. A.; Galpern, W. R.; Beal, M. F.; Breakefield ...
... such as calbindin, calretinin and parvalbumin. CR cells express several genes important in corticogenesis, such as reelin (RELN ... 3.0.CO;2-4. PMID 9067841. Soriano E, Del Río JA, Martínez A, Supèr H (April 1994). "Organization of the embryonic and early ... 3.0.CO;2-X. PMID 9699912. Ina A, Sugiyama M, Konno J, et al. (August 2007). "Cajal-Retzius cells and subplate neurons ... 2. Paris: Maloine.[page needed] Duckett S, Pearse AG (January 1968). "The cells of Cajal-Retzius in the developing human brain ...
... by the intestine via calbindin. PTH was one of the first hormones to be shown to use the G-protein adenylyl cyclase second ... 29 (2): 103-8. doi:10.3265/Nefrologia.2009.29.2.5154.en.full. PMID 19396314. Neer RM, Arnaud CD, Zanchetta JR, Prince R, Gaich ... 56 (2): 103-4. doi:10.1159/000133059. PMID 1672845. Marx UC, Adermann K, Bayer P, Meyer M, Forssmann WG, Rösch P (Feb 1998). " ... Parathyroid hormone 2 receptors are present at high levels on the cells of central nervous system, pancreas, testes, and ...
... this is particularly evident on the components of acetylcholinesterase and calbindin. More studies have been carried out on the ... 4 (2): 119-127. doi:10.1016/1044-5765(92)90010-Y. Pujol, S.; Cabeen, R.; Sébille, S. B.; Yelnik, J.; François, C.; Fernandez ... 2 (10): e169. doi:10.1038/tp.2012.92. PMC 3565822. PMID 23032945. Fineberg, Naomi A; Potenza, Marc N; Chamberlain, Samuel R; ... 37 (2): 267-74. doi:10.1016/j.nbd.2009.11.002. PMC 2864918. PMID 19909815. Yamashita, T; Ninomiya, M; Hernández Acosta, P; ...
Alternating compartments of dense Cat-301 and calbindin immunore- activity in layer 4A". Cerebral Cortex. 12 (7): 671-691. doi: ... 49 (2): 257-8. PMID 18516336. Schmolesky, M. "The organization of the retina and visual system". {{cite journal}}: Cite journal ...
... and calbindin-immunoreactive neurons relative to other frontal lobe regions, especially Area 14 in orbitofrontal cortex and ... 3.0.CO;2-I. PMID 11241188. This article incorporates text available under the CC BY 3.0 license. "BrainInfo". Archived from the ...
Vo T. T. B., Jeung E. B. (2009) An Evaluation of Estrogenic Activity of Parabens Using Uterine Calbindin-D9k Gene in an ... 16 (2): 57-66, quiz 55-6. doi:10.1097/01206501-200506000-00001. PMID 16036114. SCCS: Opinion on Parabens. Colipa No P82 3 May ... 54 (2): 237-42. doi:10.1111/j.1365-2672.1983.tb02612.x. PMID 6189812. Ma, Y; Marquis, RE (November 1996). "Irreversible paraben ... Freese, E; Sheu, CW; Galliers, E (2 February 1973). "Function of lipophilic acids as antimicrobial food additives". Nature. 241 ...
... by their expression of calbindin and calretinin. In the reeler DG, the two cell types intermingle. Impaired dendrite outgrowth ... 50 (2): 192-205. doi:10.1007/BF02996215. PMID 24539699. S2CID 37918631. D'Arcangelo G, Miao GG, Chen SC, Soares HD, Morgan JI, ... 11 (1-2): 45-58. doi:10.3109/01677069609107062. PMID 10876649. Ammassari-Teule M, Sgobio C, Biamonte F, Marrone C, Mercuri NB, ... "Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2". Cell. 97 ...
... the last being calbindin positive. The ventral tier is considered as A9v. The dorsal tier A9d is linked to an ensemble ... 4 (2): 129-138. doi:10.1016/1044-5765(92)90011-P. Sasaki M, Shibata E, Tohyama K, Takahashi J, Otsuka K, Tsuchiya K, Takahashi ... 3.0.CO;2-X. PMID 10516600. Feigenbaum Langer, L.; Jimenez-Castellanos, J. & Graybiel, A.M. (1991). The substantia nigra and its ... 660 (2): 216-224. doi:10.1016/0006-8993(94)91292-0. PMID 7820690. Lavoie, B., Smith, Y., Parent, A. (1989). "Dopaminergic ...
Among GABAergic interneurons, reelin seems to be detected predominantly in those expressing calretinin and calbindin, like ... 112 (1-2): 33-45. doi:10.1016/S0169-328X(03)00032-9. PMID 12670700. Hack I, Hellwig S, Junghans D, Brunne B, Bock HH, Zhao S, ... 6 (2): 150-9. doi:10.1038/sj.mp.4000850. PMID 11317216. Zhang H, Liu X, Zhang C, Mundo E, Macciardi F, Grayson DR, Guidotti AR ... 1 (2): 72-73. doi:10.1046/j.1535-7597.2001.00017.x. PMC 320825. PMID 15309195. Zaki M, Shehab M, El-Aleem AA, Abdel-Salam G, ...
Matrix cells of the thalamus, or calbindin-immuno-reactive neurons (CIR neurons), are widely distributed and diffusely ... 2. p. 1796. Bibcode:2007SchpJ...2.1796G. doi:10.4249/scholarpedia.1796. Jones E.G. (1975). "Some aspects of the organization of ... 20 (2): 257-268. doi:10.1016/j.concog.2010.08.003. PMC 3056940. PMID 21078562. Freeman W.; Watts J.K. (1942). "Prefrontal ... 20 (2): 464-486. doi:10.1016/j.concog.2011.01.007. PMID 21349742. S2CID 6099949. (Articles with short description, Short ...
... calbindin, and X-arrestin. The cone outer segments (OS) remained positive for cone opsins and peripherin-2 (rds/peripherin). ...
... expansion mutations lead to migration impediment in the rostral cortex coupled with a developmental deficit of calbindin- ... 2010 Mar;16(2):69-75. doi: 10.1097/NRL.0b013e3181d1416c. Citation on PubMed ...
Infection of the enteric nervous system by Borna disease virus (BDV) upregulates expression of calbindin D-28k. Vet Microbiol. ... Viral sequences of 2 birds did not match any of the described sequences and clustered together in a new branch termed ABV-6. ... Notably, in 2 samples, nucleotide sequences obtained from brain and proventriculus of the same parrot differed in the N coding ... The 2 ABV-6 genogroup sequences, which were detected in birds from Austria and Switzerland, are from geographically close areas ...
... L. Pasti;G. Carmignoto;T. Pozzan;BATTINI, ... In other regions where calbindin D(28k) protein was not modified by the construct and in all glial cells whether from wild type ... In other regions where calbindin D28k protein was not modified by the construct and in all glial cells whether from wild type ... In other regions where calbindin D28k protein was not modified by the construct and in all glial cells whether from wild type ...
Calbindin 2 - Preferred Concept UI. M0579266. Scope note. A calbindin protein that is differentially expressed in distinct ... A calbindin protein that is differentially expressed in distinct populations of NEURONS throughout the vertebrate and ...
Tytu orygina u: Calbindin-1 association and Parkinsons disease.. Czasopismo: European Journal of Neurology. Szczeg y: 2010 : ... 2/50. Autorzy: Jaros aw Dulski, Michael G. Heckman, Launia J. White, Kamila ur-Wyrozumska, Troy C. Lund, Zbigniew K. Wszolek.. ... 72, nr 1-2, s. 64-71. p-ISSN: 0014-3022. Charakt. formalna: AZ. Charakt. merytoryczna: ORG. Charakt. OPI: AIF. Wska nik Impact ... 17, nr 2, s. 208-211, bibliogr. 21 poz.. p-ISSN: 1351-5101. Charakt. formalna: AZ. Charakt. merytoryczna: ORG. Charakt. OPI: ...
The ratios of calbindin-D28K content (with vitamin D/without vitamin D) were 2.2 ± 0.2, 4.7 ± 0.5, and 7.1 ± 1.5 for young, ... The ratios of calbindin-D28K content (with vitamin D/without vitamin D) were 2.2 ± 0.2, 4.7 ± 0.5, and 7.1 ± 1.5 for young, ... The ratios of calbindin-D28K content (with vitamin D/without vitamin D) were 2.2 ± 0.2, 4.7 ± 0.5, and 7.1 ± 1.5 for young, ... The ratios of calbindin-D28K content (with vitamin D/without vitamin D) were 2.2 ± 0.2, 4.7 ± 0.5, and 7.1 ± 1.5 for young, ...
SOY MODULATION OF CALBINDIN D28k-modulates calcium channel activity and neuronal firing. Calbindin D28k is a neuroprotective ... In the amygdale a similar pattern of expression was seen to that of the calbindin results. Consumption of phytoestrogens via a ... Altered calbindin-D28 levels modify sexually dimorphic brain structure during neural development by buffering ca2+ that is ... 2006, Soybean isoflavones changes calbindin D-28k (CB) immunoreactivity in the hippocampus in female rats as well as male rats ...
regenerative activity (mcm2, nestin, olig2, calbindin), degeneration (at8/phosphorylated tau. ) and mossy-fiber pathway re- ... Brain pathology (Zurich, Switzerland) vol 28 issue 2 2018 28019685. we suggest that this tau. opathy variant with hippocampal. ... Brain pathology (Zurich, Switzerland) vol 28 issue 2 2018 28019685. in addition, accumulation of tau. immunoreactive ... Brain pathology (Zurich, Switzerland) vol 28 issue 2 2018 28019685. common neuropathological features included neuronal loss in ...
Of retinal interneurons, GABAergic neurons were more vulnerable to the iron toxicity than calbindin (+) horizontal neurons. ... Orthodenticle homeobox 2. High Otx2 levels induce photoreceptor cell fate but not bipolar cell fate. Low levels of Otx2 impair ... a) Cell clusters visualized using t- ... 3 photoreceptor, 2 horizontal cell, 12 bipolar cell, 7 amacrine cell, 7 RGC, and 3 non ... 2) The amino acid sequence of GCAP-2 between Lys29 and Phe48 that includes the EF-hand-related motif EF-1 is essential both for ...
A human endogenous retrovirus (HERV) sequence upstream of the calbindin gene, CALB1, promotes the transcription of an HERVH- ... The authors propose that in lung squamous cell carcinoma (LUSC), HERVH-driven isoforms of calbindin (HERVH-CALB1) counteract ... describe the role of chimeric calbindin 1 (CALB1) transcripts, which are driven by an upstream human endogenous retrovirus ... This increased expression of calbindin reduces CXCL8 chemokine production and downstream neutrophil recruitment in LUSC tumor ...
... with striking loss of the neurons that lack the calcium-binding proteins parvalbumin and calbindin. In rat hippocampal sections ... These 2 types of inhibition in a neuronal network are defined on the basis of the time of activation of the GABAergic neuron ... The 2 major kinds of brain surgery for epilepsy are palliative and potentially curative. The use of a vagal nerve stimulator ( ... Calculations show that the interictal spikes need to spread to about 6 cm2 of cerebral cortex before they can be detected with ...
... rabbit calbindin (Abcam, 1:200), chicken MAP-2 (Abcam, 1:1,000), rabbit calretinin (Abcam, found 1:200), rabbit parvalbumin ( ... hsFLP, C155-Gal4, UAS-mCD8::GFP; enough FRT2A tubPGal80 or hsFLP, tubPGal80, FRT19A; 109(2)80-Gal4, UAS-mCD8::GFP. For time- ... 2 mM MgCl2, 70 mM KCl, and 15% sucrose) AZD2281 solubility dmso for consecutive immunostaining and flow cytometry analysis. ... 2 × 4H2O, 2.1g MgSO4 × 7H2O, 34 g NaCl, 119 g HEPES, to 1 l dd H2O [pH 7. ...
4I-K,R-W). Consistent with this, at E16.5 there was severe reduction or loss of calbindin+ Purkinje cells and GABAergic DCN ... 2G). At E13.5,Lhx1/5+ c2 cells initiate expression of the Purkinje cell-specific marker calbindin as they migrate toward the ... They may be newly born Purkinje cells that do not express calbindin yet or progenitors of Golgi cells or GABAergic DCN neurons ... Arrowheads in A′ indicate double-labeled cells, arrow indicates a subpopulation of c2 cells that are calbindin negative. ...
Calbindin staining revealed degeneration and loss of Purkinje cells in 14-week old Xpg−/− mice (Figure 4C). Also, calbindin ... C) Representative images of calbindin immunostained sagittal cerebellum sections of 4- and 14-week old Xpg−/− and wt mice. ... To obtain evidence for the occurrence of neuronal death, we analyzed calbindin staining in cerebellar cortex where it outlines ... Primary antibodies (supplier; dilutions) used in this study were as follows: rabbit anti-Calbindin (Swant; 1∶10,000); goat anti ...
More specifically, the upregulation of ENaC combined with a lack of enrichment of calbindin D-28K, expressed in the CCD, and UT ... These results, together with the absence of expression enrichment of Calbindin D-28K and UT-A, and enrichment of expression of ... Calbindin D-28K, expressed in the DCT/CNT/cortical collecting duct (CCD)), Slc4a1 (Anion exchanger 1, expressed in type A ICs, ... C. M. E. Ammerlaan2,3, J. Schreurs1, L. Hooijmaijers1, J. Jansen4,5,6, M. B. Rookmaaker3, I. Orhon1, M. C. Verhaar3 and J. G. ...
Expression of calbindin-D9k and vitamin D receptor in the uterus of Egyptian buffalo during follicular and luteal phases. Emam ... 2019 vol: 34 (2) pp: 115-130. Triggering of a Dll4-Notch1 loop impairs wound healing in diabetes. Zheng X, Narayanan S, Sunkari ... 2019 vol: 10 (2) pp: 129. A fluorescein-based chemosensor for "turn-on" detection of Hg2+ and the resultant complex as a ... I 2 catalyzed access of spiro[indoline-3,4′-pyridine] appended amine dyad: new ON-OFF chemosensors for Cu2+ and imaging in ...
Staining of Purkinje nerve cells with mouse anti-calbindin D28K (a calcium binding protein, green). C. Confocal merge of NgR ... 2. Anti-Nogo Receptor (extracellular) Antibody, preincubated with Nogo Receptor (extracellular) Blocking Peptide (#BLP-NT008). ... 2,3 Other myelin proteins also identified as axonal growth inhibitors are the myelin-associated glycoprotein (MAG) a sialic- ...
... of human cells staining positive for the Purkinje cell marker calbindin by day 70 of differentiation. This protocol, which ... fibroblast growth factor 2 (FGF2), and the transforming growth factor β (TGFβ)-receptor blocker SB431542-hiPSCs could be ... of human cells staining positive for the Purkinje cell marker calbindin by day 70 of differentiation. This protocol, which ... fibroblast growth factor 2 (FGF2), and the transforming growth factor β (TGFβ)-receptor blocker SB431542-hiPSCs could be ...
... of human cells staining positive for the Purkinje cell marker calbindin by day 70 of differentiation. This protocol, which ... fibroblast growth factor 2 (FGF2), and the transforming growth factor β (TGFβ)-receptor blocker SB431542-hiPSCs could be ... of human cells staining positive for the Purkinje cell marker calbindin by day 70 of differentiation. This protocol, which ... fibroblast growth factor 2 (FGF2), and the transforming growth factor β (TGFβ)-receptor blocker SB431542-hiPSCs could be ...
2 microglobulin associates with class I-like molecules such as CD1 and Qa as well as with the alpha chain of MHC class I ... 2 microglobulin is an 11 kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small ... Human Beta 2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant ... Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic ...
Human CALB(Calbindin) ELISA Kit. *Human CAPN1(Calpain 1, Large Subunit) ELISA Kit ... Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) Polyclonal Antibody (Human, Pig), APC-Cy7. 4-PAD981Hu01-APC-Cy7 Cloud-Clone * ... Human Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) ELISA Kit. SED981Hu-10x96wellstestplate Cloud-Clone 10x96-wells test ... Human Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) ELISA Kit. SED981Hu-1x48wellstestplate Cloud-Clone 1x48-wells test ...
D3.633.100.759.758.824.175 Calbindin 1 D12.776.641.87 D12.776.631.87 Calcifediol D4.808.247.222.159.478.250 D4.210.500.247. ... ELAV-Like Protein 2 D12.776.641.520.500 D12.776.631.520.500 ELAV-Like Protein 3 D12.776.641.520.750 D12.776.631.520.750 ELAV- ... 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine D3.438.79.800 D3.633.100.79.800 2-Aminopurine D3.438.759.138.50 ... quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy- D3.438.834.700 D3.633.100.834.700 4- ...
Expert consulting and customized experimental design RNA, miRNA, and DNA isolation from any sample type (blood, serum, tissue, LCM, FFPE, cells).
Calbindin. CRKC3G. 0.044. v-CRK Proto-Oncogene/Rap guanine nucleotide exchange factor 1. ... A) Time course shows a sustained ppERK when calcium is above amplitude threshold (2 μM) for 1 s duration. (B) Total ppERK ... If adjusted R2 for linear is less than 0.9, then the best model is determined by AIC. ... A) Five pathways are included in the model: calcium activation of (1) RasGRF followed by RasGTP production or (2) CaMKII ...
S100G: calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium- ... 9 kDa CaBP; Calbindin-D9k; Cholecalcin; S100 calcium-binding protein G; Vitamin D-dependent calcium-binding protein, intestinal ... Protein S100-G, S100 calcium-binding protein G, Vitamin D-dependent calcium-binding protein intestinal, CABP, Calbindin-D9k, 9 ... protein S100-G; 9 kDa CaBP; S100 calcium-binding protein G; calbindin 3, (vitamin D-dependent calcium binding protein); ...
Human-specific organization of primary visual cortex: alternating compartments of dense Cat-301 and calbindin immunoreactivity ... MOXD2P (monooxygenase, DBH-like 2, pseudogene ) 2007 2016-07-25 Effects of thalamic lesions on complex perception and memory. J ... PAK2 (p21 activated kinase 2) 2010 2016-07-25 Sociosexuality from Argentina to Zimbabwe: a 48-nation study of sex, culture, and ...
Goffigan-Holmes J, Sanabria D, DIaz J, Flock D, Chavez-Valdez R. Calbindin-1 Expression in the Hippocampus following Neonatal ... Ophthalmology 2020; 127(2): 167-176. doi.org/10.1016/j.ophtha.2019.08.027 ...
  • Partial sequences of nucleoprotein (p40) and matrix protein (gp18) genes showed that virus in most of our cases belonged to the ABV-2 and ABV-4 groups among the 5 genogroups described so far. (cdc.gov)
  • CELLULAR calcium handling was examined in brain slices from transgenic antisense mice with a regional deficiency in the neuronal calcium binding protein calbindin D-28k and from their non transgenic wild type litter mate controls. (unimore.it)
  • This effect was selective and was seen only in brain areas where the antisense construct produced a significant depletion of calbindin D-28k protein. (unimore.it)
  • In other regions where calbindin D28k protein was not modified by the construct and in all glial cells whether from wild type or transgenic mice, cellular calcium handling was normal. (unimore.it)
  • A calbindin protein that is differentially expressed in distinct populations of NEURONS throughout the vertebrate and invertebrate NERVOUS SYSTEM, and modulates intrinsic neuronal excitability and influences LONG-TERM POTENTIATION. (bvsalud.org)
  • In vivo studies have indicated that renal calbin-din-D 28K protein and mRNA levels decrease in adult and old rats, and this decrease parallels the age-associated decline in serum 1, 25-dihydroxyvitamin D 3 [1, 25-(OH) 2 D 3 ] levels. (researchwithrutgers.com)
  • Calbindin-D 28K protein levels were determined by Western blot and enzyme-linked immunosorbent assay. (researchwithrutgers.com)
  • In young animals, the levels of calbindin-D28K declined from 12.1 ± 1.3 μg/mg protein in the intact kidney to 1.6 ± 0.07 μg/mg protein in cells that had been cultured for 3 days in the absence of 1, 25-(OH) 2 D 3 . (researchwithrutgers.com)
  • This sharp decline in calbindin-D 28K protein concentration moderated by days 6-8. (researchwithrutgers.com)
  • In a recent study, Attig and colleagues identified a transcription factor-activated molecular switch that circumvents cellular senescence through increased expression of the calbindin protein. (bvsalud.org)
  • A human endogenous retrovirus (HERV) sequence upstream of the calbindin gene, CALB1, promotes the transcription of an HERVH-CALB1 transcript through a splice event at the third CALB1 exon in a process known as protein exaptation. (bvsalud.org)
  • B. Staining of Purkinje nerve cells with mouse anti-calbindin D28K (a calcium binding protein, green). (alomone.com)
  • 2 microglobulin is an 11 kDa protein associated with the outer membrane of many cells including lymphocytes. (neobiolab.com)
  • Lyophilized B2M althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution B2M should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. (neobiolab.com)
  • S100G: calbindin D9K, a vitamin D-dependent calcium-binding protein. (assaygenie.com)
  • C. Confocal merge of NgR and calbindin D28K demonstrates some co-localization of these proteins. (alomone.com)
  • All four RP retinas showed loss of rods, ranging from mild (T-17-M), to more severe (P-23-H), to advanced degeneration (Q-64-ter and G-106-R). The majority of cones in the T-17-M and P-23-H retinas were cytologically normal but showed loss of immunoreactivity for the cytoplasmic proteins 7G6, calbindin, and X-arrestin. (nih.gov)
  • Further maturation was observed following dissociation and co-culture of these cerebellar progenitors with mouse cerebellar cells, with 10% of human cells staining positive for the Purkinje cell marker calbindin by day 70 of differentiation. (ox.ac.uk)
  • Calbindin 1, fibroblast growth factor 20, and alpha-synuclein in sporadic Parkinson's disease. (cdc.gov)
  • However, diminished renal responsiveness to 1, 25-(OH) 2 D 3 with advancing age could also contribute to decreased calbindin-D 28K expression. (researchwithrutgers.com)
  • These studies suggested that the observed in vivo decrease in renal calbindin-D 28K with age is primarily due to the lowered circulating 1, 25-(OH) 2 D 3 . (researchwithrutgers.com)
  • CD8 T cells cannot develop in the absence of MHC class I.Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinaemia, renal failure, or kidney transplants. (neobiolab.com)
  • Human Beta 2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumors and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy). (neobiolab.com)
  • Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. (neobiolab.com)
  • Beta-2 microglobulin levels might also be elevated in multiple myeloma and lymphoma cases. (neobiolab.com)
  • Confirmation that somatic mutations of beta-2 microglobulin correlate with a lack of recurrence in a subset of stage II mismatch repair deficient colorectal cancers from the QUASAR trial. (cdc.gov)
  • Depolarization of brain slices with NMDA or potassium produced a prolonged elevation of neuronal calcium signal in neurons in brain slices from calbindin D-28k-deficient transgenic mice. (unimore.it)
  • Una calbindina que se expresa de forma diferencial en poblaciones definidas de NEURONAS en el SISTEMA NERVIOSO de vertebrados e invertebrados, modula la excitabilidad intrínseca neuronal e interviene en la POTENCIACIÓN A LARGO PLAZO. (bvsalud.org)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) in Tissue homogenates, cell lysates and other biological fluids. (allelisakits.com)
  • The ratios of calbindin-D 28K content (with vitamin D/without vitamin D) were 2.2 ± 0.2, 4.7 ± 0.5, and 7.1 ± 1.5 for young, adult, and old cells, respectively. (researchwithrutgers.com)
  • 2. Anti-Nogo Receptor (extracellular) Antibody, preincubated with Nogo Receptor (extracellular) Blocking Peptide (#BLP-NT008). (alomone.com)
  • Proventricular dilatation disease (PDD), a serious and frequent disease of predominantly psittacine birds, was reported for the first time in the late 1970s and early 1980s in the United States, in Germany, and in Switzerland ( 1 , 2 ). (cdc.gov)
  • Although a possible viral cause has been considered since the disease was recognized ( 1 , 2 ), and electron microscopic examination of affected tissues showed structures suggestive of viral particles, no convincing evidence for infection with a specific virus has been produced in the past 30 years. (cdc.gov)
  • This increased expression of calbindin reduces CXCL8 chemokine production and downstream neutrophil recruitment in LUSC tumor cells. (bvsalud.org)
  • The low levels of calbindin-D 28K in the cells cultured in the absence of 1, 25-(OH) 2 D 3 provided an excellent experimental system in which to compare the response of the cells to 1, 25-(OH) 2 D 3 between age groups. (researchwithrutgers.com)
  • Very limited amounts of MHC class I molecules can be found on the surface in the absence of ?2 microglobulin. (neobiolab.com)
  • In cultured cells treated with 1, 25-(OH) 2 D 3 for 72 h, calbindin-D 28K induction was greater in cells from adult and old animals compared to cells from young animals. (researchwithrutgers.com)
  • The cone outer segments (OS) remained positive for cone opsins and peripherin-2 (rds/peripherin). (nih.gov)
  • Expression of Calbindin D-28k (CALB) was found in 96% of submucous and 67% of myenteric BDV-immunoreactive neurons. (nih.gov)
  • The Ventral Tegmental Area has calbindin neurons with the capability to co-release glutamate and dopamine into the nucleus accumbens. (nih.gov)
  • A calbindin protein that is differentially expressed in distinct populations of NEURONS throughout the vertebrate and invertebrate NERVOUS SYSTEM , and modulates intrinsic neuronal excitability and influences LONG-TERM POTENTIATION . (nih.gov)
  • We present for the first time ocular ultrastructure and autoantibodies of MAR. The autopsied eyes of a metastatic cutaneous melanoma patient and positive retinal autoantibodies were examined with histopathology including transmission electron microscopy, and immunohistochemistry (Calbindin, PKC-alpha, and TRPM1). (nih.gov)
  • Intracerebroventricular administration of the synthetic cannabinoid WIN55,212-2 to rats prevent βA-induced microglial activation, cognitive impairment, and loss of neuronal markers. (nih.gov)
  • Aberrant immuno-reactivities illustrated blurred condensed bipolar dendritic structure (TRPM1), tightly packed INL (PKC), and loss of ONL (calbindin), which suggested abnormal TRPM1 cation channels of retinal ON bipolar cells. (nih.gov)
  • Other human malformation syndromes caused by inborn errors of cholesterol synthesis include Lathosterolosis, Desmosterolosis, X-linked dominant chondrodysplasia punctata type 2 (CDPX2), and Congenital Hemidysplasia with Ichthyosiform Erythroderma and Limb Defects (CHILD syndrome). (nih.gov)
  • We have performed brain histological analysis on an MCT8-deficient subject and histological, ultrastructural, and magnetic resonance imaging (MRI) analysis in the brain of a mouse model of the syndrome, lacking MCT8 and enzyme deiodinase type 2 (DIO2, Mct8/Dio2 KO). (bvsalud.org)