A di-tert-butyl PHENOL with antioxidant properties.
Mixture of 2- and 3-tert-butyl-4-methoxyphenols that is used as an antioxidant in foods, cosmetics, and pharmaceuticals.
Antioxidant for foods, fats, oils, ethers, emulsions, waxes, and transformer oils.
Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.
A group of compounds that are derivatives of methoxybenzene and contain the general formula R-C7H7O.
Antineoplastic agent that is also used as a veterinary anesthetic. It has also been used as an intermediate in organic synthesis. Urethane is suspected to be a carcinogen.
Compounds in which one or more of the ketone groups on the pyrimidine ring of barbituric acid are replaced by thione groups.
A group of compounds that contain a bivalent O-O group, i.e., the oxygen atoms are univalent. They can either be inorganic or organic in nature. Such compounds release atomic (nascent) oxygen readily. Thus they are strong oxidizing agents and fire hazards when in contact with combustible materials, especially under high-temperature conditions. The chief industrial uses of peroxides are as oxidizing agents, bleaching agents, and initiators of polymerization. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.
Oxidative enzyme which transforms p-nitroanisole into p-nitrophenol.
Peroxides produced in the presence of a free radical by the oxidation of unsaturated fatty acids in the cell in the presence of molecular oxygen. The formation of lipid peroxides results in the destruction of the original lipid leading to the loss of integrity of the membranes. They therefore cause a variety of toxic effects in vivo and their formation is considered a pathological process in biological systems. Their formation can be inhibited by antioxidants, such as vitamin E, structural separation or low oxygen tension.
Substances that influence the course of a chemical reaction by ready combination with free radicals. Among other effects, this combining activity protects pancreatic islets against damage by cytokines and prevents myocardial and pulmonary perfusion injuries.
Hydrocarbon rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
Peroxidase catalyzed oxidation of lipids using hydrogen peroxide as an electron acceptor.
A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.
A carcinogen that is often used in experimental cancer studies.
A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.

Inhibition of expression of P-selectin by antioxidant in cholesterol-fed rats. (1/222)

Butylated hydroxytoluene (BHT) can inhibit experimental atherosclerosis in animals. Although the agent is an antioxidant, the exact mechanism of the reaction in atherosclerosis is still unknown. To investigate the effects of BHT on expression of P-selectin (PADGEM, GMP-140), intercellular adhesion molecule-1 (ICAM-1) and class II MHC (Ia) antigen, we proposed an experiment on rats. Male rats (n=18 per group) were fed either a normal cholesterol control diet, a normal cholesterol diet containing 0.5% BHT (BD), a high cholesterol diet containing 1.5% cholesterol and 0.1% sodium cholate (CD), or the CD diet containing 0.5% BHT (BCD). Rats were sacrificed after 3 days, and after 1, 2, 4, 10, and 17 weeks of dietary treatment. Although there was no gross or light microscopic atherosclerotic lesions, scanning electron microscopy revealed monocytic adhesion to aortic endothelium and mild endothelial injuries in CD and BCD groups. Immunohistochemically, the addition of BHT to a high cholesterol diet inhibited P-selectin expression but not in ICAM-1 and Ia antigen. These findings suggest that in rats, high cholesterol diets induce expression of ICAM-1, P-selectin and Ia antigen. In addition, the antiatherogenic effect of BHT may play a role in the inhibition of P-selectin.  (+info)

Antioxidants reversibly inhibit the spontaneous resumption of meiosis. (2/222)

We previously showed that the cell-permeant antioxidant 2(3)-tert-butyl-4-hydroxyanisole (BHA) inhibited germinal vesicle breakdown (GVBD) in oocyte-cumulus complexes (OCC) of the rat. The objective of the present studies was to assess other antioxidants and whether such inhibition was reversible. Spontaneous GVBD in OCC incubated for 2 h was significantly inhibited (P < 0.005) by nordihydroguaiaretic acid (NDGA; GVBD = 19.4%), BHA (GVBD = 25.7%), octyl gallate (OG; GVBD = 52.2%), ethoxyquin (EQ; GVBD = 58.8%), 2, 6-di-tert-butyl-hydroxymethyl phenol (TBHMP; GVBD = 59%), butylated hydroxytoluene (BHT; GVBD = 59.5%), and tert-butyl hydroperoxide (TBHP; GVBD = 60.0%). Other antioxidants that produced lower but significant (P < 0.05) inhibition of oocyte maturation included propyl gallate (PG; GVBD = 70.3%), 2,4,5-trihydroxybutrophenone (THBP; GVBD = 71.4%), and lauryl gallate (LG; GVBD = 71.4%). Antioxidants that had no effect on oocyte maturation at the same concentration (100 microM) included ascorbic acid, vitamin E, and Trolox. Inhibition of GVBD was evident for up to 8 h of incubation of OCC and denuded oocytes (DO) with BHA or NDGA and was reversed by washing. NDGA was less potent than BHA for inhibition of GVBD in DO, unlike that seen with OCC. Oocyte maturation was induced by incubation of follicles for 3 h with human chorionic gonadotropin (hCG), and this response was inhibited by BHA or NDGA. These findings support the conclusion that cell-permeant antioxidants inhibit spontaneous resumption of meiosis, which may implicate a role of oxygen radicals in oocyte maturation.  (+info)

Antimalarial activities of WR-194,965, an alpha-amino-o-cresol derivative. (3/222)

Pilot appraisals of the activities of WR-194,965 and WR-204,165, two closely related o-cresol derivatives (both Mannich bases), in owl monkeys infected with the multidrug-resistant Vietnam Smith strain of Plasmodium falciparum showed that these compounds had similar levels of efficacy. Total course doses effecting 90% cures (CD(90)s) were 27 and 37 mg/kg of body weight for the respective compounds, values almost identical to the CD(90) of mefloquine (a highly promising 4-quinolinemethanol) against infections with the same strain, and the CD(90)s of chloroquine against infections with 4-aminoquinoline-susceptible strains. Expanded studies of the activities of WR-194,965 against infections with the Smith strain of P. falciparum and Vietnam Palo Alto strain of P. vivax, designed to guide projected evaluations in human volunteers, showed: (i) that the activity of this compound was a function of total dose administered, with single doses as effective as the same amount delivered in three or seven successive daily fractions; (ii) that all regimens effected rapid clearance of parasitemia; and (iii) that based on CD(90)s, this agent was twice as active against infections with the Palo Alto strain of P. vivax as against the Smith strain of P. falciparum. These findings, together with results of preclinical pharmacological studies pursued elsewhere, provided support for studies in human volunteers now underway.  (+info)

Nrf2 is essential for protection against acute pulmonary injury in mice. (4/222)

Nrf2 is a member of the "cap 'n' collar" family of transcription factors. These transcription factors bind to the NF-E2 binding sites (GCTGAGTCA) that are essential for the regulation of erythroid-specific genes. Nrf2 is expressed in a wide range of tissues, many of which are sites of expression for phase 2 detoxification genes. Nrf2(-/-) mice are viable and have a normal phenotype under normal laboratory conditions. The NF-E2 binding site is a subset of the antioxidant response elements that have the sequence GCNNNGTCA. The antioxidant response elements are regulatory sequences found on promoters of several phase 2 detoxification genes that are inducible by xenobiotics and antioxidants. We report here that Nrf2(-/-) mice are extremely susceptible to the administration of the antioxidant butylated hydroxytoluene. With doses of butylated hydroxytoluene that are tolerated by wild-type mice, the Nrf2(-/-) mice succumb from acute respiratory distress syndrome. Gene expression studies show that the expression of several detoxification enzymes is altered in the Nrf2(-/-) mice. The Nrf2(-/-) mice may prove to be a good in vivo model for toxicological studies. As oxidative damage causes DNA breakage, these mice may also be useful for testing carcinogenic agents.  (+info)

Compensatory lung growth after partial pneumonectomy enhances lung tumorigenesis induced by 3-methylcholanthrene. (5/222)

In small mammals, partial pneumonectomy (PNX) elicits rapid hyperplastic compensatory growth of the remaining lung parenchyma to restore normal lung mass, structure, and function. In BALB mice subjected to PNX, compensatory lung growth is complete within 10 days. Because cellular hyperplasia contributes to the mechanism of tumor promotion by butylated hydroxytoluene (BHT), we hypothesized that hyperplastic compensatory lung growth would promote tumor formation in carcinogen-treated animals in a manner similar to that observed after BHT. In mice subjected to PNX, within 1 week of treatment with the carcinogen 3-methylcholanthrene (MCA; 10 microg/g body weight), lung tumor multiplicity was 3-7-fold higher in animals subjected to PNX than in mice subjected to a sham operation. The increase in tumor multiplicity occurred when PNX was performed 1, 3, and 6 days before or 1 day after MCA treatment. In the absence of PNX, lung tumor multiplicity in MCA-treated mice given one injection of BHT (200 mg/kg body weight) increased significantly (P < 0.01) as compared to that in mice given MCA alone. Tumor multiplicity continued to increase linearly (R2 = 0.99) with each subsequent BHT injection. Lung tumor multiplicity and tumor size in mice given one or two injections of BHT were comparable to those in animals subjected to PNX. These data demonstrate that post-PNX compensatory lung growth stimulates tumorigenesis in MCA-treated mice and provides a novel model for investigating tumor formation.  (+info)

Effects of butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) on the acetylation of 2-aminofluorene and DNA-2-aminofluorene adducts in the rat. (6/222)

The effects of the synthetic phenolic antioxidants (butylated hydroxyanisole and butylated hydroxytoluene) on the in vivo acetylation of 2-aminofluorene and formation of DNA-2-aminofluorene adducts were investigated in male Sprague-Dawley rats. For in vitro examination, cytosols and intact cells, with or without butylated hydroxyanisole and butylated hydroxytoluene co-treatment, showed different percentages of 2-aminofluorene acetylation and DNA-2-aminofluorene adducts. For in vivo examination, pre-treatment of male rats with butylated hydroxyanisole and butylated hydroxytoluene (10 mg/kg) 48 h prior to the administration of 2-aminofluorene (50 mg/kg) resulted in 34% and 18%, 29% and 20% decreases, respectively, in the urinary and fecal recovery of N-acetyl-2-aminofluorene, and 34% and 19% decreases, respectively, in the metabolic clearance of 2-aminofluorene to N-acetyl-2-aminofluorene. Following exposure of rats to the 2-aminofluorene, with or without pretreatment with butylated hydroxyanisole and butylated hydroxytoluene, DNA-2-aminofluorene adducts were observed in the target tissues of liver and bladder, and also in circulating leukocytes. The DNA-2-aminofluorene adducts in liver, bladder, and leukocytes were decreased by pretreatment with butylated hydroxyanisole and butylated hydroxytoluene. This is the first demonstration that synthetic phenolic antioxidants decrease the N-acetylation of carcinogens and formation of DNA-carcinogen adducts in vivo.  (+info)

Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methylcholanthrene and post-natally exposed to butylated hydroxytoluene. (7/222)

The carcinogenic effects of in utero exposure to 3-methylcholanthrene (MC) have been demonstrated in the tumor-resistant C57BL/6 (B6) and DBA (D2) strains of mice. In this study, we determined the effects of in utero exposure to MC in BALB/c mice, a strain which demonstrates greater susceptibility to lung tumor induction, and compared our findings with those previously found in [D2xB6D2F(1)]F(2) mice. In addition, we assessed the molecular pathogenesis of the chemically induced tumors and examined the effects of the putative lung tumor promoter butylated hydroxytoluene (BHT) in BALB/c mice. BALB/c mice were treated on day 17 of gestation with 5, 15 or 45 mg/kg MC and 6 weeks after birth with BHT for 6 consecutive weeks. Mice were killed at 6 months of age. Ki-ras, p16Ink4a and p19ARF gene loci were amplified from paraffin-embedded lung tumor tissue and screened for the presence of point mutations via allele-specific oligonucleotide hybridization and single strand conformation polymorphism (SSCP) analyses. Ki-ras point mutations were found in 56% (20/36) of BALB/c lung tumors, with 33% (2/6) of the hyperplasias, 58% (10/19) of the adenomas and 73% (8/11) of the carcinomas exhibiting point mutations at this gene locus. Similar incidences of Ki-ras mutations were previously found following transplacental exposure of [D2xB6D2F(1)]F(2) mice to MC and treatment of adult A/J mice with urethane. Interestingly, a strain-dependent difference was observed in the mutational spectrum. Sixty-two and 38% of the lung lesions in BALB/c mice exhibited G-->C and G-->T transversions, respectively, in contrast to the 13 and 84% incidences previously observed in [D2xB6D2F(1)]F(2) mice. SSCP analysis of the tumor suppressor gene p16Ink4a showed a 6% incidence of point mutations, consistent with that found in [D2xB6D2F(1)]F(2) mice. No mutations were found in exon 1beta of the p19ARF gene of either strain. BHT, a lung tumor promoter in adult mice, had no statistically significant effects on either tumor incidence, tumor multiplicity or the mutational spectrum produced in the Ki-ras gene by in utero MC treatment. However, though not significant, there was an observable trend in increased tumor multiplicity in mice co-treated with BHT. These data demonstrate the transplacental carcinogenic effect of MC in BALB/c mice and show that mutagenic damage to Ki-ras is a critical early event mediating murine lung tumorigenesis in both the tumor-sensitive and tumor-resistant strains. Unlike what occurs when adult BALB/c mice are treated with MC, BHT does not appear to significantly promote the formation of lung tumors following transplacental exposure to MC, possibly due to the rapid growth and cell proliferation in the developing organism. Strain-dependent differences in the Ki-ras mutational spectrum may be associated with their differential susceptibility to lung tumor initiation.  (+info)

Effects of MK-447 on platelet shape change, aggregation, and ATP release by collagen, ADP, and stable analogue of thromboxane A2 in rabbit platelets. (8/222)

AIM: To investigate the effects of MK-447 on platelet shape change, aggregation, and ATP release by collagen (Col), ADP, and stable analogue of thromboxane A2 (STA2) in rabbits. METHODS: Platelet shape change and aggregation were quantified in light transmission by turbidimetric method and release reaction was assessed by the amount of ATP in platelet-rich plasma (PRP). RESULTS: (1) MK-447 100-700 mumol.L-1 caused only the shape change, which was not inhibited by indometacin 3 mumol.L-1. Platelet shape changes by Col, ADP, and STA2 were reduced (P < 0.01) after the addition of MK-447. The lag phase was prolonged (P < 0.01) in Col and shortened (P < 0.01) in ADP. (2) MK-447 reduced the aggregation by Col 5 mg.L-1 (P < 0.01), and enhanced that by ADP 0.3-10 mumol.L-1 and STA2 0.1-3 mumol.L-1 (P < 0.01). (3) The release reaction by STA2 1-3 mumol.L-1 was also increased (P < 0.01). The effects of MK-447 on STA2 were not inhibited by S-145. CONCLUSION: MK-447 induced the platelet shape change, and showed the dual effects, inhibition or enhancement, on the actions by different aggregating agents.  (+info)

... (BHT), also known as dibutylhydroxytoluene, is a lipophilic organic compound, chemically a derivative ... Butylated hydroxytoluene (BHT) (PDF) (Report). Vol. 40. World Health Organization: International Agency For Research On Cancer ... Brugh, M (1977). "Butylated hydroxytoluene protects chickens exposed to Newcastle disease virus". Science. 197 (4310): 1291-2. ... being the nearest to this). Snipes W, Person S, Keith A, Cupp J (4 April 1975). "Butylated Hydroxytoluene Inactivated Lipid- ...
... s naturally produce butylated hydroxytoluene. Cyanidin-3-glucoside represented 92% of total anthocyanins. In 1962, it was ...
Antioxidants include butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). Other preservatives include ... such as butylated hydroxyanisole, butylated hydroxytoluene, tocopherols, hinokitiol, lysozyme, nisin, natamycin, chitosan, and ...
... butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), tocopherols, hinokitiol); antimicrobial enzymes (e.g. lysozyme ...
Butylated hydroxytoluene Cyanotoxin NOAA Center of Excellence for Great Lakes and Human Health. "Cylindrospermopsis raciborskii ... Babu B, Wu JT (December 2008). "Production of Natural Butylated Hydroxytoluene as an Antioxidant by Freshwater Phytoplankton" ( ... Research has shown that C. raciborskii can naturally produce butylated hydroxytoluene, an antioxidant, food additive, and ...
Other methods include butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), Rancimat method (rancidification ... are the subject of research into the natural production of butylated hydroxytoluene (BHT), an antioxidant, food additive and ... The green alga Botryococcus braunii is the subject of research into the natural production of butylated hydroxytoluene (BHT), ... 8-16, INIST:21511068 Babu B.; Wu J. T. (December 2008). "Production of Natural Butylated Hydroxytoluene as an Antioxidant by ...
... are the subject of research into the natural production of butylated hydroxytoluene (BHT), an antioxidant, food ... Babu B, Wu JT (December 2008). "Production of Natural Butylated Hydroxytoluene as an Antioxidant by Freshwater Phytoplankton" ( ...
Babu B, Wu JT (December 2008). "Production of Natural Butylated Hydroxytoluene as an Antioxidant by Freshwater Phytoplankton" ( ... aeruginosa is the subject of research into the natural production of butylated hydroxytoluene (BHT), an antioxidant, food ...
It is a synergistic antioxidant with butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA). Octyl gallate at ...
Preservatives like parabens and benzoates and antioxidants like butylated hydroxytoluene (BHT) and sodium metabisulfite. ...
It is composed of heptane, cellulose, methyl rhenium trioxide, butylated hydroxytoluene, and polyphenol oxidase. The additive ...
Butylated hydroxytoluene (BHT): an optional additive used to prevent pyrethroid from oxidizing during burning. Piperonyl ...
For antioxidants added to food to preserve them, see butylated hydroxyanisole and butylated hydroxytoluene. In the following ...
Antioxidants such as butylated hydroxytoluene are often added to ethers to prevent this process. Due to the shock and light ...
Examples include 4-tert-butylcatechol (TBC), 4-methoxyphenol (MEHQ), butylated hydroxytoluene (BHT) and hydroquinone (HQ). Anti ...
... is consumed mainly in the production of antioxidants, such as butylated hydroxytoluene (BHT). The monoalkylated ...
To minimize this problem, commercial samples of THF are often inhibited with butylated hydroxytoluene (BHT). Distillation of ...
At low temperatures, free radical inhibitors such as hindered phenols are used, e.g. butylated hydroxytoluene. At temperatures ...
Butylated hydroxytoluene 2,4-Dimethyl-6-tert-butylphenol Para tertiary butyl phenol Peter P. Klemchuk (2005). "Antioxidants". ...
2,6-Di-tert-butylphenol Butylated hydroxytoluene Propofol (Structural isomer) List of gasoline additives Fiege H (2000). " ...
... butylated hydroxytoluene and butylated hydroxyanisole) in fish feed and commercially farmed fish". Food Addit Contam Part a ...
The cereal also contains monoglycerides and diglycerides, used to bind saturated fat, and butylated hydroxytoluene (BHT), a ...
"Intake of Butylated Hydroxyanisole and Butylated Hydroxytoluene and Stomach Cancer Risk: Results from Analyses in the ... Like butylated hydroxytoluene (BHT), the conjugated aromatic ring of BHA is able to stabilize free radicals, sequestering them ... Butylated hydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4- ... Butylated Hydroxyanisole (BHA), CAS No. 25013-16-5 Archived 2010-06-05 at the Wayback Machine, Report on Carcinogens, Eleventh ...
Antioxidants such as butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) are produced by Friedel-Crafts ...
Other antiskinning agents have been used, including phenolic antioxidants (E.G butylated hydroxytoluene), but these tend to ...
Commercial diethyl ether is typically supplied with trace amounts of the antioxidant butylated hydroxytoluene (BHT), which ...
1993). "Modification of carcinogenesis by -tocopherol, t-butylhydro-quinone, propyl gallate and butylated hydroxytoluene in a ... It can be combined with other preservatives such as butylated hydroxyanisole (BHA). As a food additive, its E number is E319. ...
"Modification of carcinogenesis by α-tocopherol, t-butylhydro-quinone, propyl gallate and butylated hydroxytoluene in a rat ...
... butylated hydroxytoluene (BHT), TBHQ, propyl gallate and ethoxyquin. The natural antioxidants tend to be short-lived, so ... Natural antioxidants include ascorbic acid (vitamin C) and tocopherols (vitamin E). Synthetic antioxidants include butylated ...
... butylated hydroxytoluene, butylated hydroxyanisole and alpha-tocopherol). Avrainvillea erecta was reported to have strong ...
... propellant Butylated hydroxyanisole (BHA) - antioxidant (fat soluble) Butylated hydroxytoluene (BHT) - antioxidant (fat soluble ...
The CAS number is 12772-68-8. Derivatives of p-cresol include: Butylated hydroxytoluene, a common antioxidant Derivatives of o- ... Cresols (also hydroxytoluene or cresylic acid) are a group of aromatic organic compounds. They are widely-occurring phenols ( ...
... pistol Butylated hydroxytoluene This disambiguation page lists articles associated with the title Bhp. If an internal link led ...
... butylated hydroxyanisole (BHA, E320) and butylated hydroxytoluene (BHT, E321). The most common molecules attacked by oxidation ... Iverson F (June 1995). "Phenolic antioxidants: Health Protection Branch studies on butylated hydroxyanisole". Cancer Letters. ...
... a former Turkish airline Bosnia and Herzegovina Television Broken Hill type ore deposit Butylated hydroxytoluene, an organic ...
Tetrasodium glutamate diacetate Sodium chloride Proprietary inert filler Sodium formate Fragrance Butylated hydroxytoluene ...
... butylated hydroxytoluene MeSH D02.755.239.327 - creosote MeSH D02.755.239.402 - cyclofenil MeSH D02.755.239.493 - ... butylated hydroxyanisole MeSH D02.355.601.250 - bis(chloromethyl) ether MeSH D02.355.601.400 - enflurane MeSH D02.355.601.536 ... butylated hydroxyanisole MeSH D02.755.075.536 - guaiacol MeSH D02.755.075.536.400 - guaifenesin MeSH D02.755.075.536.400.500 - ... butylated hydroxyanisole MeSH D02.355.726.453 - guaiacol MeSH D02.355.726.453.400 - guaifenesin MeSH D02.355.726.750 - ...
... essential oil in salami has been shown to increase the higher synthetic antioxidant effect of butylated hydroxytoluene, which ...
The molecular formula C15H24O may refer to: Butylated hydroxytoluene, a food additive Khusimol Nonylphenol 1-Nonyl-4-phenol α- ...
Butylated hydroxytoluene, Acid Blue 25, Acid red 88, Deionized Water v t e (Articles with short description, Short description ...
... which contained butylated hydroxytoluene (BHT). However, Hari claims that BHT is not as toxic if applied to skin as opposed to ... Hari launched a petition on her website asking General Mills and Kellogg's to remove the preservative butylated hydroxytoluene ...
Butylated hydroxytoluene (E321) Afoxolaner is recommended to be administered at a dose of 2.7-7 mg/kg dog's body weight. ...
... such as butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA), tocopherols, hinokitiol, lysozyme, nisin, natamycin ...
Testing Status of Butylated hydroxytoluene 10575-K. Testing Status of Butylated hydroxytoluene 10575-K. CASRN: 128-37-0. ... Bioassay of Butylated Hydroxytoluene (BHT) for Possible Carcinogenicity (CASRN 128-37-0) ...
Butylated Hydroxytoluene,. 2,6-Di-tert-Butyl-4-Methylphenol,. Dibutylated Hydroxytoluene Description. White crystals or ...
What is the use of butylated hydroxytoluene?. What is the use of butylated hydroxytoluene?. BHT (butylated hydroxytoluene) is a ... What does butylated hydroxytoluene mean?. butylated hydroxytoluene. noun. mass noun. A synthetic antioxidant used to preserve ... What is the abbreviation for butylated hydroxytoluene (BHT)?. Butylated hydroxytoluene ( BHT ), also known as ... What is butyl hydroxy toluene?. Butylated Hydroxy Toluene, butylhydroxytoluene, or BHT is a fat-soluble organic compound in a ...
Butylated hydroxytoluene (BHT) is an antioxidant used in rubber and plastic. It can oxidize to form a dark yellow oily liquid ... butylated hydroxytoluene.jpg~Chemical structure]]] == Other Properties == Soluble in toluene, methanol, ethanol, isopropanol, ...
... "butylated"[All Fields] AND "hydroxytoluene"[All Fields]) OR "butylated hydroxytoluene"[All Fields]) OR ((c12[All Fields] AND 20 ... citronellol, AND (R) AND butylated hydroxytolue... (41709) 64-17-5 OR .beta. citronellol, AND (R) AND butylated hydroxytoluene ... Search instead for 64-17-5 OR .BETA.-CITRONELLOL, (R)- OR BUTYLATED HYDROXYTOLUENE OR C12-20 ACID PEG-8 ESTER OR CETEARYL ... citronellol, (R) butylated hydroxytoluene OR c12-20 acid peg-8 ester OR cetearyl ethylhexanoate OR ethylhexylglycerin OR ...
BUTYLATED HYDROXYTOLUENE (UNII: 1P9D0Z171K) (BUTYLATED HYDROXYTOLUENE - UNII:1P9D0Z171K) BUTYLATED HYDROXYTOLUENE. 6 [hp_X] in ... Butylated Hydroxytoluene 6X, 12X, 30X, 12C, 30C, Caffeic Acid 6X, 12X, 30X, 12C, 30C, Chlorogenic Acid 6X, 12X, 30X, 12C, 30C, ... butylated hydroxytoluene, caffeic acid, chlorogenic acid, cinnamic acid, coniferyl alcohol, coumarinum, dopamine hydrochloride ... butylated hydroxytoluene, caffeic acid, chlorogenic acid, cinnamic acid, coniferyl alcohol, coumarinum, dopamine hydrochloride ...
Toll-like receptor 4 in butylated hydroxytoluene-induced mouse pulmonary inflammation and tumorigenesis Alison K Bauer 1 , ... Toll-like receptor 4 in butylated hydroxytoluene-induced mouse pulmonary inflammation and tumorigenesis Alison K Bauer et al. J ... Butylated hydroxytoluene exposure is necessary to induce lung tumors in BALB mice treated with 3-methylcholanthrene. Malkinson ... Pharmacologic and genetic studies on the modulatory effects of butylated hydroxytoluene on mouse lung adenoma formation. ...
... a reduction of vitamin K-dependent blood clotting factor activity and incidence of haemorrhagic death in rats fed butylated ... hydroxytoluene (BHT); however, the vitamin K status of the animals used in these studies was claimed to be inadequate. The aim ... The dose-dependent effect of BHT (butylated hydroxytoluene) on vitamin K-dependent blood coagulation in rats S Cottrell 1 , C M ... The dose-dependent effect of BHT (butylated hydroxytoluene) on vitamin K-dependent blood coagulation in rats S Cottrell et al. ...
Butylated hydroxytoluene (BHT). By THM Team on February 18, 2022. Butylated hydroxytoluene (BHT) is used as a preservative. It ...
Cytogenetic Study of Butylated Hydroxytoluene in Chinese Hamster Ovary Cell Sister Chromatid Exchange Test ... Butylated hydroxytoluene (128-37-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National ... TR-150 Bioassay of Butylated Hydroxytoluene (BHT) for Possible Carcinogenicity (CASRN 128-37-0). *[Abstract] ... Cytogenetic Study of Butylated Hydroxytoluene in Chinese Hamster Ovary Cell Chromosome Aberrations Test ...
Bioassay of Butylated Hydroxytoluene (BHT) for Possible Carcinogenicity (CASRN 128-37-0)Chemical (Study Title) ... Butylated hydroxytoluene: Target Organs and Levels of Evidence for TR-150. Bioassay of Butylated Hydroxytoluene (BHT) for ... Butylated hydroxytoluene. 128-37-0. 12/13/1978. Dosed-Feed. 0,3000,6000 PPM/50 PER GROUP. Frederick Cancer Research Facility. ...
Butylated hydroxytoluene. 128-37-0. GO7875000. Butylene hydrate. 78-92-2. EO1750000. ...
The results were also compared with standards i.e. Butylated hydroxytoluene (BHT). Besides, the polyphenol and flavonoid ...
Butylated hydroxytoluene. HAT. Hydrogen atom transfer. ET. Electron transfer. ORAC. Oxygen radical absorbance assay. ...
N2 - Butylated hydroxytoluene (BHT) is a synthetic phenolic antioxidant that has been used as an additive for fat- or oil- ... AB - Butylated hydroxytoluene (BHT) is a synthetic phenolic antioxidant that has been used as an additive for fat- or oil- ... Butylated hydroxytoluene (BHT) is a synthetic phenolic antioxidant that has been used as an additive for fat- or oil-containing ... Ham, J., Lim, W., Whang, K. Y., & Song, G. (2020). Butylated hydroxytoluene induces dysregulation of calcium homeostasis and ...
Calcitriol capsules contain butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) as antioxidants. The capsules ...
butane, butylated hydroxytoluene, cetyl alcohol, citric acid, dehydrated alcohol, isobutane, lactic acid, polysorbate 60, ...
Each capsule also contains medium chain triglycerides, alcohol, and butylated hydroxytoluene. The medium chain triglycerides ...
Inactive Ingredients: butylated hydroxytoluene, carnauba wax, cellulose acetate, hypromellose, lactose, phosphoric acid, ... CONCERTA® also contains the following inert ingredients: butylated hydroxytoluene, carnauba wax, cellulose acetate, ...
BHT free (Butylated Hydroxy Toluene). *Chlorine free. *PVC free. TEMPERATURE:*20° - 150° F ...
Some, such as sodium nitrite, propyl gallate, butylated hydroxyanisole (BHA), and butylated hydroxytoluene (BHT) have been ...
Benzoate preservatives (BHT, BHA, TBHQ). These preservatives - butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA) ...
BHT (Butylated Hydroxytoluene). A toluene-based preservative that may be linked to skin irritation. ...
Butylated hydroxytoluene can protect polyunsaturated fatty acids in dried blood spots from degradation for up to 8 weeks at ...
Also, BHT (Butylated hydroxytoluene) is found in commercial cookies and is used to preserve them and does the same thing. ...
  • BHA (butylated hydroxyanisole) and BHT (butylated hydroxytoluene) are closely related synthetic antioxidants used as preservatives in lipsticks and moisturizers, among other cosmetics. (roadlesstraveledstore.com)
  • 3. Estimated daily intakes of butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and tert-butyl hydroquinone (TBHQ) antioxidants in Korea. (nih.gov)
  • 8. Cytotoxicity and apoptosis induction by butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). (nih.gov)
  • 16. Butylated hydroxyanisole, butylated hydroxytoluene and tert. (nih.gov)
  • These preservatives - butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA) and tertiary butylhydroquinone (TBHQ) - are added to foods containing fat. (livescience.com)
  • Butylated Hydroxyanisole (BHA) and Butylated Hydroxytoluene (BHT) are used to preserve fats and inhibit the formation of yeast. (bewellbuzz.com)
  • Butylated Hydroxy Toluene, butylhydroxytoluene, or BHT is a fat-soluble organic compound in a white powder form that is primarily used as an antioxidant food additive and cosmetics and, pharmaceuticals. (roadlesstraveledstore.com)
  • 14. Quantitative identification of and exposure to synthetic phenolic antioxidants, including butylated hydroxytoluene, in urine. (nih.gov)
  • The applicant has shown that antioxidants such as butylated hydroxytoluene (BHT) can delay or prevent galactosemic and diabetic cataractogenesis formation in rats even though the lens polyol levels in the antioxidant-treated group were twice as much as in the corresponding galactosemic and diabetic groups with mature cataract. (nih.gov)
  • 7. Butylated hydroxytoluene induces hyperactivity and alters dopamine-related gene expression in larval zebrafish (Danio rerio). (nih.gov)
  • Butylated hydroxytoluene (BHT) is a synthetic phenolic antioxidant that has been used as an additive for fat- or oil-containing foods. (korea.ac.kr)
  • Also, BHT (Butylated hydroxytoluene) is found in commercial cookies and is used to preserve them and does the same thing. (beliefnet.com)
  • Search Results for: Acetaldehyde OR Acetylcholine OR APIOLE PARSLEY OR Ascorbic acid OR BUTYLATED HYDROXYTOLUENE OR Caffeic acid OR Candida albicans OR Cinnamic acid OR Coniferyl Alcohol OR Coumarin OR Dopamine OR ESTRONE OR Gallic acid OR ".GAMMA. (nih.gov)
  • Butylated hydroxytoluene ( BHT ), also known as dibutylhydroxytoluene, is a lipophilic organic compound, chemically a derivative of phenol, that is useful for its antioxidant properties. (roadlesstraveledstore.com)