ButylaminesPerindopril: An angiotensin-converting enzyme inhibitor. It is used in patients with hypertension and heart failure.Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.Angiotensin-Converting Enzyme Inhibitors: A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.Biological Products: Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.Materia Medica: Materials or substances used in the composition of traditional medical remedies. The use of this term in MeSH was formerly restricted to historical articles or those concerned with traditional medicine, but it can also refer to homeopathic remedies. Nosodes are specific types of homeopathic remedies prepared from causal agents or disease products.Health Food: A non-medical term defined by the lay public as a food that has little or no preservatives, which has not undergone major processing, enrichment or refinement and which may be grown without pesticides. (from Segen, The Dictionary of Modern Medicine, 1992)Consumer Product SafetyAmines: A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)Odors: The volatile portions of substances perceptible by the sense of smell. (Grant & Hackh's Chemical Dictionary, 5th ed)PropylaminesSpermidine Synthase: An enzyme that catalyzes the transfer of the propylamine moiety from 5'-deoxy-5'-S-(3-methylthiopropylamine)sulfonium adenosine to putrescine in the biosynthesis of spermidine. The enzyme has a molecular weight of approximately 73,000 kDa and is composed of two subunits of equal size.Glycosides: Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)Disaccharides: Oligosaccharides containing two monosaccharide units linked by a glycosidic bond.Xylenes: A family of isomeric, colorless aromatic hydrocarbon liquids, that contain the general formula C6H4(CH3)2. They are produced by the destructive distillation of coal or by the catalytic reforming of petroleum naphthenic fractions. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Vibration: A continuing periodic change in displacement with respect to a fixed reference. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Gases: The vapor state of matter; nonelastic fluids in which the molecules are in free movement and their mean positions far apart. Gases tend to expand indefinitely, to diffuse and mix readily with other gases, to have definite relations of volume, temperature, and pressure, and to condense or liquefy at low temperatures or under sufficient pressure. (Grant & Hackh's Chemical Dictionary, 5th ed)Enbucrilate: A tissue adhesive that is applied as a monomer to moist tissue and polymerizes to form a bond. It is slowly biodegradable and used in all kinds of surgery, including dental.Dibutyl Phthalate: A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.Methyl n-Butyl Ketone: An industrial solvent which causes nervous system degeneration. MBK is an acronym often used to refer to it.Fraud: Exploitation through misrepresentation of the facts or concealment of the purposes of the exploiter.Counterfeit Drugs: Drugs manufactured and sold with the intent to misrepresent its origin, authenticity, chemical composition, and or efficacy. Counterfeit drugs may contain inappropriate quantities of ingredients not listed on the label or package. In order to further deceive the consumer, the packaging, container, or labeling, may be inaccurate, incorrect, or fake.IndiaMedicare Assignment: Concept referring to the standardized fees for services rendered by health care providers, e.g., laboratories and physicians, and reimbursement for those services under Medicare Part B. It includes acceptance by the physician.Foxes: Any of several carnivores in the family CANIDAE, that possess erect ears and long bushy tails and are smaller than WOLVES. They are classified in several genera and found on all continents except Antarctica.Anti-Arrhythmia Agents: Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.tert-Butyl AlcoholMethyl Ethers: A group of compounds that contain the general formula R-OCH3.Pseudomonas mendocina: A species of gram-negative bacteria in the genus PSEUDOMONAS, which is found in SOIL and WATER.Ethyl EthersAmiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.Phosphines: Inorganic or organic compounds derived from phosphine (PH3) by the replacement of H atoms. (From Grant & Hackh's Chemical Dictionary, 5th ed)Hydrogen: The first chemical element in the periodic table. It has the atomic symbol H, atomic number 1, and atomic weight [1.00784; 1.00811]. It exists, under normal conditions, as a colorless, odorless, tasteless, diatomic gas. Hydrogen ions are PROTONS. Besides the common H1 isotope, hydrogen exists as the stable isotope DEUTERIUM and the unstable, radioactive isotope TRITIUM.Hydrogenase: An enzyme found in bacteria. It catalyzes the reduction of FERREDOXIN and other substances in the presence of molecular hydrogen and is involved in the electron transport of bacterial photosynthesis.Oxidation-Reduction: A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).Catalysis: The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.Electron Probe Microanalysis: Identification and measurement of ELEMENTS and their location based on the fact that X-RAYS emitted by an element excited by an electron beam have a wavelength characteristic of that element and an intensity related to its concentration. It is performed with an electron microscope fitted with an x-ray spectrometer, in scanning or transmission mode.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Spectrometry, X-Ray Emission: The spectrometric analysis of fluorescent X-RAYS, i.e. X-rays emitted after bombarding matter with high energy particles such as PROTONS; ELECTRONS; or higher energy X-rays. Identification of ELEMENTS by this technique is based on the specific type of X-rays that are emitted which are characteristic of the specific elements in the material being analyzed. The characteristic X-rays are distinguished and/or quantified by either wavelength dispersive or energy dispersive methods.Extracellular Space: Interstitial space between cells, occupied by INTERSTITIAL FLUID as well as amorphous and fibrous substances. For organisms with a CELL WALL, the extracellular space includes everything outside of the CELL MEMBRANE including the PERIPLASM and the cell wall.Cardiac Imaging Techniques: Visualization of the heart structure and cardiac blood flow for diagnostic evaluation or to guide cardiac procedures via techniques including ENDOSCOPY (cardiac endoscopy, sometimes refered to as cardioscopy), RADIONUCLIDE IMAGING; MAGNETIC RESONANCE IMAGING; TOMOGRAPHY; or ULTRASONOGRAPHY.Signal Detection, Psychological: Psychophysical technique that permits the estimation of the bias of the observer as well as detectability of the signal (i.e., stimulus) in any sensory modality. (From APA, Thesaurus of Psychological Index Terms, 8th ed.)Phosphorus: A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.Ethylene Glycols: An ethylene compound with two hydroxy groups (-OH) located on adjacent carbons. They are viscous and colorless liquids. Some are used as anesthetics or hypnotics. However, the class is best known for their use as a coolant or antifreeze.Drug Contamination: The presence of organisms, or any foreign material that makes a drug preparation impure.Phthalic Acids: A group of compounds that has the general structure of a dicarboxylic acid-substituted benzene ring. The ortho-isomer is used in dye manufacture. (Dorland, 28th ed)Solvents: Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)Glycols: A generic grouping for dihydric alcohols with the hydroxy groups (-OH) located on different carbon atoms. They are viscous liquids with high boiling points for their molecular weights.PennsylvaniaGlass: Hard, amorphous, brittle, inorganic, usually transparent, polymerous silicate of basic oxides, usually potassium or sodium. It is used in the form of hard sheets, vessels, tubing, fibers, ceramics, beads, etc.Dental Clasps: Metal devices for fastening together two or more parts of dental prostheses for stabilizing or retaining them by attachment to abutment teeth. For a precision attachment for a partial denture DENTURE PRECISION ATTACHMENT is available.Plastics: Polymeric materials (usually organic) of large molecular weight which can be shaped by flow. Plastic usually refers to the final product with fillers, plasticizers, pigments, and stabilizers included (versus the resin, the homogeneous polymeric starting material). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Pliability: The quality or state of being able to be bent or creased repeatedly. (From Webster, 3d ed)Resins, Synthetic: Polymers of high molecular weight which at some stage are capable of being molded and then harden to form useful components.

Action potentials, contraction, and membrane currents in guinea pig ventricular preparations treated with the antispasmodic agent terodiline. (1/87)

Terodiline was widely prescribed for urinary incontinence before reports of adverse cardiac effects that included bradycardia, QT lengthening, and ventricular tachyarrhythmia. The present study on guinea pig papillary muscles and ventricular myocytes was undertaken to gain insight into the cardioactive properties of the drug. Clinically relevant concentrations (<10 microM) of terodiline lengthened the action potential duration by up to 12%; higher concentrations shortened the duration in a concentration-dependent manner. The drug depressed maximal upstroke velocity in a use-dependent manner; the IC(50) value was near 150 microM in muscles driven at 1 Hz, 60 microM at 3 Hz, 38 microM at 5 Hz, and 3 microM at 1 Hz in muscles depolarized with 14 mM K(+). Submicromolar terodiline frequently had a small positive inotropic effect, whereas micromolar concentrations depressed force in a frequency-dependent manner. Voltage-clamp results on myocytes indicate that terodiline inhibits three membrane currents that govern repolarization: 1) E4031-sensitive, rapidly activating K(+) current with an IC(50) value near 0.7 microM as previously reported; 2) slowly activating, delayed-rectifier K(+) current with an IC(50) value of 26 microM; and 3) L-type Ca(2+) current with an IC(50) value of 12 microM. These findings are correlated with the changes in action potential configuration and developed tension and discussed in relation to the cardiotoxic effects of the drug.  (+info)

Block and modified gating of cardiac calcium channel currents by terodiline. (2/87)

1. Terodiline, an anticholinergic/antispasmodic drug effective in the treatment of urinary incontinence, is presently restricted due to adverse side effects on cardiac function. To characterize its effects on cardiac L-type Ca2+-channel current carried by Ca2+ (ICa, L) and Ba2+ (IBa,L), concentrations ranging from 0.1 to 100 microM were applied to whole-cell-configured guinea-pig ventricular myocytes. 2. Although sub-micromolar concentrations of terodiline had no effect on ICa,L at 0 mV, 100 microM drug reduced its amplitude to ca. 10% of pre-drug control. The estimated IC50 (15.2 microM in K+-dialysed cells, 12.2 microM in Cs+-dialysed cells; 0.1 Hz pulsing rate) is eight times higher than reported for ICa,L in bladder smooth muscle myocytes. 3. Terodiline affected ICa,L in a use-dependent manner; block increased when the pulsing rate was increased from 0.1 to 2 - 3 Hz, and when holding potential was lowered from -43 mV. The drug accelerated the decay of ICa,L at 0 mV in a concentration-dependent manner, and slowed the recovery of channels from inactivation. 4. Terodiline reduced peak IBa,L more effectively than peak ICa,L, and markedly accelerated the rate of inactivation of the current. 5. The results are discussed in terms of mechanisms of Ca2+ channel block and relation to the therapeutic and cardiotoxic effects of the drug.  (+info)

Lysyl oxidase coupled with catalase in egg shell membrane. (3/87)

The activity of lysyl oxidase was found in egg shell membrane (ESM) of hens. The activity was determined by measuring the enzymatic conversion of n-butylamine and Nalpha-acetyl-L-lysine to n-butyraldehyde and Nalpha-acetyl-L-allysine, respectively. ESM lysyl oxidase was significantly inhibited by beta-aminopropionitrile, chelating agents, and deoxygenation, consistent with the known properties of lysyl oxidase. Nevertheless, ESM lysyl oxidase was insoluble in urea solution, suggesting that it complexes with ESM. These findings support previous reports indicating the presence of lysine-derived cross-links in ESM and the necessity of lysyl oxidase located in the isthmus of the hen oviduct for the biosynthesis of ESM. Lysyl oxidase secreted around the egg white from the isthmus may initiate the cross-linking reaction of ESM protein, and remain as the constituent of ESM. Moreover, the H(2)O(2) released by lysyl oxidase in ESM was completely decomposed by coexisting catalase activity. ESM lysyl oxidase activity was greatly elevated in the presence of H(2)O(2), probably due to the O(2) produced by catalase. These findings indicate that lysyl oxidase is coupled with catalase in ESM. This coupling enzyme system was considered to be involved in the biosynthesis of ESM and to protect the embryo against H(2)O(2).  (+info)

Increased hindrance on the chiral carbon atom of mexiletine enhances the block of rat skeletal muscle Na+ channels in a model of myotonia induced by ATX. (4/87)

1 The antiarrhythmic drug mexiletine (Mex) is also used against myotonia. Searching for a more efficient drug, a new compound (Me5) was synthesized substituting the methyl group on the chiral carbon atom of Mex by an isopropyl group. Effects of Me5 on Na+ channels were compared to those of Mex in rat skeletal muscle fibres using the cell-attached patch clamp method. 2 Me5 (10 microM) reduced the maximal sodium current (INa) by 29.7+/-4.4 % (n=6) at a frequency of stimulation of 0.3 Hz and 65.7+/-4.4 % (n=6) at 1 Hz. At same concentration (10 microM), Mex was incapable of producing any effect (n=3). Me5 also shifted the steady-state inactivation curves by -7. 9+/-0.9 mV (n=6) at 0.3 Hz and -12.2+/-1.0 mV (n=6) at 1 Hz. 3 In the presence of sea anemone toxin II (ATX; 5 microM), INa decayed more slowly and no longer to zero, providing a model of sodium channel myotonia. The effects of Me5 on peak INa were similar whatever ATX was present or not. Interestingly, Me5 did not modify the INa decay time constant nor the steady-state INa to peak INa ratio. 4 Analysis of ATX-induced late Na+ channel activity shows that Me5 did not affect mean open times and single-channel conductance, thus excluding open channel block property. 5 These results indicate that increasing hindrance on the chiral atom of Mex increases drug potency on wild-type and ATX-induced noninactivating INa and that Me5 might improve the prophylaxis of myotonia.  (+info)

CYP2D6 and CYP2C19 genotypes of patients with terodiline cardiotoxicity identified through the yellow card system. (5/87)

AIMS: Terodiline has concentration dependent QT prolonging effects and thus the potential for cardiotoxicity. Pharmacogenetic variation in terodiline metabolism could be responsible for cardiotoxicity. We sought to determine whether CYP2D6 (debrisoquine hydroxylase) or CYP2C19 (S-mephenytoin hydroxylase) status is a risk factor for terodiline cardiotoxicity. METHODS: Using the UK Yellow Card scheme to identify patients, blood samples were obtained from eight patients who survived ventricular tachycardia or torsades de pointes suspected to be due to terodiline, for determination of CYP2D6 and CYP2C19 genotypes. Genotype prevalence was compared with that in published general population groups. RESULTS: One patient was a CYP2D6 poor metaboliser (CYP2D6*4 homozygous) and a second was heterozygous for CYP2D6*4, a slightly lower frequency for these genotypes compared with the general population (P = 0.31). In the case of CYP2C19, one patient was a poor metaboliser and four were heterozygous for the variant CYP2C19*2 allele, compared with general population frequencies of 2% and 23%, respectively (P = 0.035). CONCLUSIONS: These findings suggest that debrisoquine poor metaboliser status is not primarily responsible for terodiline cardiotoxicity. However, possession of the CYP2C19*2 allele appears to contribute to adverse cardiac reactions to terodiline. The present study demonstrates the feasibility of using spontaneous adverse drug reaction reporting schemes to determine the contribution of genotype for metabolizing enzymes to uncommon adverse drug reactions.  (+info)

Differences in the effects of urinary incontinence agents S-oxybutynin and terodiline on cardiac K(+) currents and action potentials. (6/87)

1. The cardiac electrophysiological effects of S-oxybutynin, a single-enantiomer drug under evaluation for the management of urinary incontinence, have been investigated and compared with those of terodiline, an incontinence agent withdrawn following reports of QT lengthening and ventricular tachyarrhythmia. Membrane currents were recorded from whole-cell configured guinea-pig and rabbit ventricular myocytes, and action potentials were recorded from guinea-pig and rabbit papillary muscles. 2. L-type Ca(2+) current (I:(Ca,L)), rapidly-activating K(+) current (I:(Kr)) and slowly-activating K(+) current (I:(Ks)) were unaffected by submicromolar S-oxybutynin and inhibited by higher concentrations; IC(50) values were 17.8 microM for I:(Ca,L), 12 microM for I:(Kr), and 41 microM for I:(Ks). Terodiline IC(50) values were somewhat lower for I:(Ca,L) (15.2 microM) and I:(Ks) (30 microM), but 24 fold lower in the case of I:(Kr) (0.5 microM). 3. The durations of action potentials in guinea-pig and rabbit papillary muscles driven at 1 Hz were unaffected or moderately shortened by 0.1 - 100 microM S-oxybutynin, but lengthened by terodiline. Terodiline (< or =10 microM) also depressed maximal upstroke velocity. 4. The action potential plateau shortened by an average of 23% when control rabbit papillary muscles were driven at 0.4 Hz instead of 1 Hz. Plateau shortening was significantly smaller in the presence of drugs (30 microM S-oxybutynin, 3 and 30 microM terodiline), suggesting that they suppress the transient outward current (I:(to)) involved in rate-dependent shortening. In experiments on rabbit ventricular myocytes, 3 and 30 microM S-oxybutynin inhibited I:(to) by 9+/-2% and 35+/-3%, respectively, whereas 3 and 30 microM terodiline inhibited the current by 31+/-3% and 87+/-3%, respectively. 5. The results indicate that S-oxybutynin has relatively weak non-specific effects on cardiac ion channels, and that clinically relevant submicromolar concentrations are unlikely to have terodiline-like proarrhythmic actions on the myocardium.  (+info)

New pathway of amine oxidation respiratory chain of Paracoccus denitrificans IFO 12442. (7/87)

The physiological electron acceptor of quinohemoprotein amine dehydrogenase (QH-AmDH) from Paracoccus denitrificans IFO 12442 was identified by biochemical and electrochemical methods. Of three types of heme c-containing proteins purified together with QH-AmDH from the periplasm of n-butylamine-grown cells, only constitutive cytochrome c-550 was reduced by the addition of QH-AmDH and n-butylamine. Reconstitution of the respiratory chain revealed that cytochrome c-550 mediates the electron transfer from QH-AmDH to the terminal oxidase. This is a new pathway of the amine oxidation respiratory chain of P. denitrificans.  (+info)

Comparison of the omega-transaminases from different microorganisms and application to production of chiral amines. (8/87)

Microorganisms that are capable of (S)-enantioselective transamination of chiral amines were isolated from soil samples by selective enrichment using (S)-alpha-methyl-benzylamine ((S)-alpha-MBA) as a sole nitrogen source. Among them, Klebsiella pneumoniae JS2F, Bacillus thuringiensis JS64, and Vibrio fluvialis JS17 showed good omega-transaminase (omega-TA) activities and the properties of the omega-TAs were investigated. The induction level of the enzyme was strongly dependent on the nitrogen source for the strains, except for V. fluvialis JS17. All the omega-TAs showed high enantioselectivity (E>50) toward (S)-alpha-MBA and broad amino donor specificities for arylic and aliphatic chiral amines. Besides pyruvate, aldehydes such as propionaldehyde and butyraldehyde showed good amino acceptor reactivities. All the omega-TAs showed substrate inhibition by (S)-alpha-MBA above 200 mm. Moreover, substrate inhibition by pyruvate above 10 mm was observed for omega-TA from V. fluvialis JS17. In the case of product inhibition, acetophenone showed much greater inhibitions than L-alanine for all omega-TAs. Comparison of the enzyme properties indicates that omega-transaminase from V. fluvialis JS17 is the best one for both kinetic resolution and asymmetric synthesis to produce enantiomerically pure chiral amines. Kinetic resolution of sec-butylamine (20 mM) was done under reduced pressure (150 Torr) to selectively remove an inhibitory product (2-butanone) using the enzyme from V. fluvialis JS17. Enantiomeric excess of (R)-sec-butylamine reached 94.7% after 12 h of reaction.  (+info)

Dibutylamine 111-92-2 MSDS report, Dibutylamine MSDS safety technical specifications search, Dibutylamine safety information specifications ect.
Establishing a Protocol for the Long-term Sampling and Analysis of Tick-borne Pathogens in the Lehigh Valley Rachel Heist1 1Department of Infectious Diseases, Lehigh Valley Health Network Abstract The blackedlegged tick, Ixodes scapularis, transmits several human pathogens including the spirochete that causes Lyme disease (Borellia burgdorferi), which is endemic to the Lehigh Valley region of eastern Pennsylvania. Additional tick-borne diseases have also been emerging in the region including tick-borne relapsing fever (caused by Borrelia miyamotoi), human granulocytic anaplasmosis (caused by Anaplasma phagocytophilum), and human babesiosis (caused by Babesia microti). The dog tick, Dermacentor variabilis, is capable of transmitting Rocky Mountain Spotted Fever (caused by Rickettsia rickettsii). To determine the entomological risk of infection by a tick-borne pathogen, a protocol was established to gather data for a long-term study. Eleven collection sites were screened and selected for analysis
terodiline: lipophilic drug with oral bioavailability of 80%; formerly used as antianginal drug; may be used to treat motor urge incontinence in women; withdrawn by manufacturer pending further safety evaluation, Vet Res 1991;129(14):319
Viscosities of dilute solutions of n-propylamine, n-butylamine, di-n-propylamine, di-n-butylamine, tri-n-propylamine and tri-n-butylamine in toluene, and of tri-n-butylamine in benzene, have been measured at 303.15 K. The values of viscosity deviations are negative for all the amine solutions and their magnitude increases with the increase in concentration of alkylamine. The specific viscosities and excess Gibbs energy of activation of viscous flow, based on Eyrings theory of absolute reaction rates, are of varying magnitude and sign depending upon the viscosities and type and nature of solute and solvent molecules. The specific viscosities have been analyzed in terms of Herskovits and Kelly equation and Nakagawa equation. The change in Gibbs activation energy and the heat of solution per mole of solute (alkylamine) at infinite dilution in cyclohexane, benzene and toluene solutions have been calculated in terms of the transition state theory ...
Benzonatate is a medication used for the treatment of coughing in adults and children over the age of 10. This eMedTV resource contains more drug information on benzonatate, including details on how the medicine works and a list of potential side effects.
Buy Benzonatate online without prescription in USA, Canada, Australia, UK and Europe. Fast order delivery. Worldwide shipping. FDA approved RX online pharmacy.
Choking and other serious problems can occur if benzonatate capsules are not swallowed whole. This eMedTV resource offers additional important safety precautions for benzonatate, including warnings on who should avoid the drug entirely.
After your bladder has been resting during catheterization, it needs to be retrained to fill and empty. You may have to go more frequently for awhile.
Benzonatate is used to treat cough in patients with the pneumonia, bronchitis, emphysema, asthma and other breathing problems as well as the common cold, as stated by WebMD. The medication works by...
Benzonatate and Children. Benzonatate should not be given to children younger than 10 years of age.3,4,5 Accidental overdoses have occurred in this age group because the gelatin capsules can look like candy to children.5 There are reports that accidental ingestion by children can lead to seizure, coma, cardiac arrest, and death.3,5 In 2010, the US Food and Drug Administration (FDA) issued a warning to keep the drug away from young children. They recommend that parents keep the pills in childproof containers, out of sight or reach.10. Benzonatate and the Elderly. There are no specific dosing recommendations for benzonatate use in older individuals. Medication dose and frequency follows the adult recommendations.4 If you are of older age, use this medication cautiously.. Side effects such as dizziness and drowsiness can potentially increase your risk for falls. If you have dementia, your confusion may become worse with this medication. Constipation can also be a significant problem in elderly ...
View drug interactions between Alka-Seltzer Plus Night Cold Formula Liquid and benzonatate. These medicines may also interact with certain foods or diseases.
Literature References: Quinoline methanol antimalarial agent. Prepn (stereo unspec): C. J. Ohnmacht et al., J. Med. Chem. 14, 926 (1971). Prepn, activity, and abs config of isomers: F. I. Carroll, J. T. Blackwell, J. Med. Chem. 17, 210 (1974). Prepn of erythro-form: G. Grethe, T. Mitt, DE 2806909; H. Bömches, B. Hardegger, US 4507482 (1978, 1985 both to Hoffmann-La Roche). X-ray crystal structure: A. Skórska et al., Bioorg. Med. Chem. Lett. 16, 850 (2006). Mechanism of action studies: M. W. Davidson et al., J. Med. Chem. 20, 1117 (1977); R. E. Brown et al., Life Sci. 25, 1857 (1979). Photochemistry: G. A. Epling, U. C. Yoon, Chem. Lett. 1982 (2), 211. Pharmacokinetics: D. E. Schwartz et al., Chemotherapy (Basel) 28, 70 (1982). HPLC determn in blood and plasma: I. M. Kapetanovic et al., J. Chromatogr. 277, 209 (1983). Comprehensive description: P. Lim, Anal. Profiles Drug Subs. 14, 157-180 (1985). Review of development: Bull. WHO 61, 169-178 (1983); of clinical trials in malaria prophylaxis: A. ...
The FDA recently warned that accidental ingestion of the antitussive benzonatate (Tessalon Perles, and others) by children less than 10 years old can be fatal.1 This widely prescribed oral agent, which has been available in the US since 1958, can also cause severe morbidity and death in older children and adults, and not only in overdosage.. Benzonatate is a polyglycol derivative structurally related to procaine and tetracaine. It acts peripherally on stretch receptors in the lower respiratory tract to suppress the cough reflex. If the patient chews or sucks the liquid-filled capsules or "softgels", the drug can cause laryngospasm, bronchospasm and circulatory collapse. Adverse effects that can occur after swallowing an intact capsule include a feeling of numbness in the chest, mental confusion, a sensation of burning in the eyes, and visual hallucinations.. Taken in overdose, benzonatate ... more ...
Nonsurgical treatment options for urinary incontinence include behavioral changes that bring relief, such as limiting fluid intake and avoiding caffeine; bladder retraining and pelvic floor...
I had a lap done last year to remove endo but they didnt remove all of it and have got bladder problems since having it done. I am on bladder retraining and that means i have to self catheterize most...
13952-84-6 sec-Butylamine testing. Laboratory testing for CAS number 13952-84-6. sec-Butylamine;Butafume;Propylamine, 1-Methyl-;Tutane;1-Methylpropanamine;1-Methylpropylamine;2-Aminobutane;2-AB;2-Butylamine;sec-C4H9NH2;sec-Butanamine;Deccotane;Frucote;2-Aminobutane base;(Rs)-2-aminobutane;(Rs)-sec-butylamine;Secondary butylamine;CSC 2-Aminobutane. This chemical is colourless liquid with an amine odour
Practically 70 of North Carolina highschool seniors have had intercourse. I hade my last interval on 9th nov 2013 and did intercourse on 17th and 23rd nov 2013. 1999;5(6):354-366. Because each PMS temper swings and Pregnancy emotional modifications are benzonatate pregnancy safe identical to each other, it can be exhausting to tell whether you are just PMSing or if youre pregnant based on this symptom alone. It is believed that progesterone acts as an appetite stimulant, whereas estrogen regulates the urge for food. Sleeping for 8 hours or extra without waking up to eat will cause your blood sugar to drop. If you notice these signs, ensure to inform your health care supplier at your subsequent appointment. This occurs when the developing embryo implants into the lining of the benzonatate pregnancy safe and is named an implantation bleed. Many find that merely being induced pregnancy 37 weeks your body round this soft log is the perfect fit for their pregnant body. Eat healthy meals. Week 22: ...
Physiotherapy is a holistic healthcare profession that aims to help those affected by injury, illness or disability. Physiotherapists specialize in the assessment, diagnosis, and treatment of a variety of neurological, orthopedic, and cardiorespiratory conditions. In Ontario, individuals can see physiotherapists without a doctors referral.. Pelvic floor physiotherapy is the assessment and treatment of various conditions including, but not limited to, conditions of the muscles, bones, connective tissues, and ligaments surrounding the pelvis. This is a specialty within the physiotherapy profession, and is conducted by registered physiotherapists who have also undergone further education.. A typical initial appointment will include a detailed internal and external examination of your pelvis, a discussion of the findings as well as a possible treatment plan specifically tailored to your needs. This treatment may include additional internal pelvic floor therapy, bladder retraining, stretching, and ...
The FVGR is dropped to the seafloor; once there, it lowers four, square "grabs" into the sediment. The grabs enclose a specified volume of sediments, the water overlying the sediments, and the animals and microbes living within them. Right now, and for up to five days from now, these grabs will be left in place, measuring oxygen concentrations in the overlying water to measure the amount of biological activity occurring in the sediment. Through these measurements, estimates of sediment community oxygen consumption (SCOC)-a way of measuring biological activity on the seafloor-have been tracked for over 20 years at Station M. Through long-term sampling, the Smith lab has learned that the benthos (seafloor) at Station M, and probably other regions of the deep sea, appears to consume oxygen at a higher rate than the food arriving to the seafloor would suggest is possible. However, episodic events such as intense falls of detrital aggregates, or "marine snow," from surface waters may provide the ...
In a small study, verapamil was no more effective than placebo and less effective than oxybutynin. However, verapamil combined with oxybutynin was more effective than oxybutynin alone. Terodiline... more
Aug 1, 2008. 350 mg four times daily Not recommended for children younger than 12 years. Among antispasmodic agents, carisoprodol Soma. which shows
* found in: n-Butyl Alcohol Reagent (ACS), Butylamine, 99%, Cadmium 99.95%, Shot, Diethylene Glycol Monobutyl Ether, 99%, 2-Butoxyethanol, 99%, sec-Butyl..
Amines Market Analysis By Product (Ethanolamines, Fatty Amines, Alkylamines), Application (Crop Protection, Surfactants, Water ...
BioAssay record AID 242686 submitted by ChEMBL: In vitro inhibitory concentration towards kinesin spindle protein activity of ATP hydrolysis in the presence of microtubules measured by ATPase assay (n=3).
0040] The surface-treating composition may further include a solvent which is able to be blended with (e.g., combined with) the polymer or the reductant. For example, the solvent may include at least one selected from water, an amine, an ester, a ketone, an aliphatic or aromatic hydrocarbon, an ether, an alcohol, a polyol, an amide, a sulfone, a sulfoxide, and a combination thereof. The amine may be selected from a primary amine such as propylamine, n-butylamine, hexylamine, or octylamine; a secondary amine such as diisopropylamine or di(n-butyl)amine; a tertiary amine such as trioctyl amine or tri-n-butylamine; an alkyl amine such as ethylamine, propylamine, butylamine, hexylamine, octylamine, or trioctyl amine; a cyclic amine, and an aromatic amine. The ester may be selected from polyethylene glycol methacrylate ("PEGMFA"), ethyl acetate, N-butyl acetate, gamma butyrolactone, 2,2,4-trimethyl pentanediol-1,3-monoisobutyrate, butyl carbitol acetate, butyl oxalate, dibutyl phthalate, dibutyl ...
This work demonstrates the use of an in-capillary procedure for derivatization of amino acids, peptides, and alkylamines by anhydrides using capillary electrophoresis (CE). Migrating in an uncoated fused-silica capillary, plugs of substrate and anhyd
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Mebeverine Mebeverine is an antispasmodic agent which exerts direct action on the GI smooth muscle Pregnancy and lactation A03AA04 - mebeverineBelongs to the class of synthetic anticholinergics, esters with tertiary amino group. There are no or limited amount of data from the use of mebeverine in pregnant women. Animal studies are insufficient with respect to reproductive toxicity (see. Dapoxetine dangers safety of mebeverine for use in pregnancy has not been fully established and for this reason its not usually recommended for women who.. Mebeverine Description: Mebeverine is an antispasmodic agent which exerts direct action on the GI Pregnancy and lactation A03AA04 - mebeverine ; Belongs to the class of synthetic anticholinergics, esters with tertiary amino group. ...
Abstract: Bladder pain syndrome/interstitial cystitis (BPS/IC) is associated with symptoms of urgency, frequency, and pain in the bladder or pelvis, in the absence of infection or disease. While manual therapy skills performed by a specialized pelvic floor physiotherapist can improve pain and symptoms by as much as 75-80%,23 treatment strategies need to look beyond, because the persistent nature of this condition suggests there is also dysfunction occurring within the peripheral and central nervous systems. Other symptom-improving treatments include bladder retraining, neurophysiology-based pain education, mindfulness meditation, and a variety of other strategies to help quiet their hypersensitive nervous systems ...
Streamflow and water-quality data were collected by the U.S. Geological Survey (USGS) or the Providence Water Supply Board, Rhode Islands largest drinking-water supplier. Streamflow was measured or estimated by the USGS following standard methods at 23 streamgage stations; 10 of these stations were also equipped with instrumentation capable of continuously monitoring specific conductance. Streamflow and concentrations of sodium and chloride estimated from records of specific conductance were used to calculate instantaneous (15-minute) loads of sodium and chloride during water year (WY) 2004 (October 1, 2003, to September 30, 2004). Water-quality samples were also collected at 37 sampling stations in the Scituate Reservoir drainage area by the Providence Water Supply Board during WY 2004 as part of a long-term sampling program. Water-quality data are summarized by using values of central tendency and are used, in combination with measured (or estimated) streamflows, to calculate loads and yields (loads
1. Terodiline, an anticholinergic drug with calcium antagonist properties, is associated with QT prolongation and ventricular arrhythmias. It is not known if oxybutynin, a drug with a similar pharmacological profile, causes QT prolongation. ECGs were
Phenylisobutylamine, also known as α-ethylphenethylamine, Butanphenamine, B or AEPEA,[1] is a stimulant drug of the phenethylamine class. It is a higher homologue of amphetamine, differing from amphetamines molecular structure only by the substitution of the methyl group at the alpha position of the side chain with an ethyl group. Compared to amphetamine, phenylisobutylamine has strongly reduced dopaminergic effects, and instead acts as a selective norepinephrine releasing agent.[citation needed] The dextroisomer of phenylisobutylamine partially substitutes for dextroamphetamine in rats.[1] A number of derivatives of phenylisobutylamine are known, including BDB, MBDB, EBDB, butylone (bk-MBDB), eutylone (bk-EBDB), Ariadne (α-Et-DOM), 4-CAB, and 4-MAB. "Phenylisobutylamine" is in fact a chemical misnomer because isobutylamine itself contains a branched chain. The correct name after this style for this class of compound would be "phenylsecbutylamine". ...
Abstract. Abstract 1868Background. ARRY-520 is a kinesin spindle protein (KSP) inhibitor that has demonstrated clinical activity in patients with relapsed and
Natamycin, 50% Glucose is a naturally occurring anti-fungal agent produced during fermentation of bacterium Streptomyces natalensis. It has a purity of ...
Sweet-root (Glycirrhiza glabra L.): a plant native in the Mediterranean region and Asia, however it is cultivated all over the world. It has been used to cure gastric ulcer for a long time. Contratily to antiacid medications, sweet-root inhibits formation of ulcer by stimulating normal defense mechanism. Besides all this, it is an antiphlogistic, expectorant, antispasmodic agent ...
A couple ideas come to mind. First you should find out the source of the cough, through diagnostic testing, doesnt sound like Strep, but maybe its bactrial or viral. As for symptom relief I would highly suggest benzonatate, knwn far better by its trade name "Tessalon Perles". One, two, or three at most of them should numb your throat enough to reduce coughing and perhaps even help breathing. Also you might want to consider having a peak flow test done to check your breathing to see if an inhaler (albuterol or similar) might help (albuterol WILL induce a cough at high enough doses, so if you already havea cough thats productive, its likely to exaggerate both of those symptoms). More simply I would reccomend starting out with Claritin (loratadine) at a dosage of 20mg per day, two pills per day, since Claritin is fairly innocuous and if the issue is allergens, or even if it isnt, the Claritin, or similar drugs (zyrtec etc. but claritin is cheap and over the counter) might be a good first line. Of ...
see article for more examples. Abstract. Borane-tetrahydrofuran complex or borane-methyl sulfide complex is used to generate triacyloxyboranes, which can be effectively reacted with various nucleophiles (alkylamines, arylamines, hydrazides, alcohols, phenols) at reflux in toluene to provide the corresponding amides and esters in excellent yield.. ...
S. M. McCarthy, Y.-C. Lin, D. Devarajan, J. W. Chang, H. Yennawar, R. M. Rioux, D. H. Ess, A. T. Radosevich. Intermolecular N-H Oxidative Addition of Ammonia, Alkylamines and Arylamines to a Planar sigma3-Phosphorus Compound via an Entropy-Controlled Electrophlic Mechanism. J. Am. Chem. Soc. 136 (2014) 4640-4650 ...
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Natamycin: Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically.
Background: ALN-VSP02 is a RNA interference (RNAi) therapeutic comprised of lipid nanoparticle-formulated small interfering RNAs (siRNAs) targeting the expression of vascular endothelial growth factor (VEGF)-A and kinesin spindle protein (KSP). Methods: A multi-center, open label, phase I dose-escalation trial of ALN-VSP02 administered as a 15-minute iv infusion q2 wks was initiated in patients (pts) with advanced solid tumors and at least one measurable liver lesion. Main objectives included evaluation of safety/tolerability and assessment of PK/PD. Results: Thirty-one pts were enrolled across 7 dose levels (0.1-1.5 mg/kg); median age 57 yrs, all with multiple prior therapies. A total of 140 doses were administered, mean of 4.5 (range 1-17). Treatment was generally well-tolerated, with no dose-dependent trends in clinical or laboratory adverse events. One on-study death (liver failure in a pt with near complete replacement of the liver by tumor) deemed possibly related to treatment occurred at ...
1. Hawthorn. This thorny shrub has been long used to treat heart disease. It possesses potent antioxidant flavonoids which improve blood glow, dilate the blood vessels, and protect them from potential damage. The leaves and buds of this herb contain higher amount of flavonoids when compared to the berries. According to a study done on hawthorn, participants who took hawthorn extract for sixteen weeks had lower blood pressure than the placebo.. 2. Lime Blossom. The flowers of this herb have been long used to heal issues like anxiety. They contain volatile oil, flavonoids, and mucilage component, all of which work in synergy to soothe inflammation. Interestingly, linden works as potent sedative, diuretic, astringent, and antispasmodic agent.. 3. Mistletoe. It has been scientifically shown that mistletoe neutralizes blood sugar levels in diabetics and helps treat cardiovascular disease. It is capable of soothing rheumatic and arthritic pain, too.. 4. Hibiscus. In one study male participants aged 30 ...
User:Etienne Robillard,Etienne Robillard]] 15:26, 5 February 2013 (EST): Thus, do you accept the spraying of humans with C(2)-phenoxy alkylamines reagents for the purpose of human genomic experiments, even such experiments were possibly lead by German scientists under the cover of your present or past government? And for what good reason do you assert Synthetic Biology is not a genuine indoctrination of your own consciousness, to let you not even objectify your own dissent agaisnt such human-specific experiments with psychotropic phenoxyalkylamine like alkyloids? . Lastly, do you object agaisnt militarisation of science and development of bioweapons by proceeding in unethical dual-purpose research to engineer virus-like particles (compounds) on the false likelyhood of saving humanity from X-Men attacks (ie flumageddon ...
The Dynamic Neural Retraining System™ is a natural, drug- free, neuroplasticity-based healing program that can help you recover from many health conditions.
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Natamycin Market: Overview Natamycin is also known commonly as pimaricin or natacyn. It is an anti-fungal agent produced during aerobic fermentation by the Streptomyces natalensis, a bacterium found commonly in soil. Natamycin is a polyene macrolide anti-biotic Natamycin is sparingly soluble in water and required in very low concentrations. available as an odorless, white, granular…
Posted By Andree on December 16, 1998 at 18:25:37: In Reply to: Re: Urethra/bladder operation for detrusor instability posted by HFHS M.D.-CK on December 15, 1998 at 10:56:43: I was won...
It is suggested that human γδ T cells play significant roles during intracellular infections, such as tuberculosis (20), malaria (21), ehlrichosis (22), and many others (23, 24, 25, 26, 27, 28, 29, 30, 31). Evidence indicates that human T cells bearing Vγ2Vδ2-TCR, which constitute the vast majority of γδ T cells in healthy adults, respond to unique Ags in the extracts and/or supernatants of these bacteria and protozoa and are activated with respect to proliferation, cytokine production, and cytotoxic activity (17). These Ags include nonpeptide molecules such as a wide variety of small organic pyrophosphomonoesters (3, 4, 5, 7) and alkylamines (12) as well as unprocessed protein Ags (32, 33, 34). Although it has been indicated that the response takes place in a Vγ2Vδ2-TCR-dependent manner based on substantial evidence including the TCR gene transfer studies (15), knowledge of how human γδ T cells recognize such molecules has remained elusive.. It was indicated previously that activation ...
A major part of the preparations in this group are combined preparations. Preparations containing e.g. analgesics and antispasmodics could be classified either in this group or in N02 - Analgesics. Combinations of psycholeptics and antispasmodics could be classified in A03 or in N05 - Psycholeptics etc. The main indication for the use of the combination will, together with the relative effect of the active components, decide the classification. In the treatment of pain caused by spasms, the spasmolytic component must be judged as more important than the analgesic component. Accordingly, analgesic/antispasmodic combinations should be classified in A03 if the main effect of the preparation is the antispasmodic action ...
CV Pharmacology Vaughan-Williams Classification of - Atropine official prescribing information for healthcare professionals. Drug Class. Anticholinergic chronotropic agents Anticholinergics / antispasmodics
Calm-gen has antispasmodic and neuroregulatory properties that help take the edge off and assist in balancing the stresses of daily living. This remedy acts a
... is a chapter in the book, Urology, containing the following 9 pages: Interstitial Cystitis, Urinary Incontinence, Functional Incontinence, Low Pressure Urethra, Overflow Incontinence, Stress Incontinence, Pelvic Floor Exercise, Urge Incontinence, Bladder Retraining Drill.
Abstract. The analysis of bioactive was done by used gas chromatography-mass spectroscopy(GC-MS) method then antifungal and antimicrobial activity for methanolic extract was measured in the lab. The analysis of Morganella morganii by GC-MS revealed the existence of the Tricyclo, 3-Methoxybenzaldehyde semicarbazone , undecan-1-amine, carboxaldehyde , 1-methyl-,oxime ,(Z)-(+), 4-(2,5-Dihydro-3-methoxyphenyl) butylamine , Paromomycin , 1,5,5-Trimethyl-6-methylene-cyclohexene, 9-Borabicyclo[3.31], Benzenemethanol , nonane , 9-mercapto-2-(2-aminopropoxy)-3-methyl, Acetamide , N-(6-acetylaminobenzothiazol-2-yl)-2-(adamantan, rin-6-carboxylic acid , N-(2,5-Dicyano-3,4-dihydro-2H-pyrrol-2-yl)- acetamide, 3,10-Dioxatricyclo4-(2,5-Dihydro-3-methoxyphenyl)butylamine, [4.3.1.0(2,4)] phenylmethyl ester, 3,7-Diazabicyclo dec-7-ene, 3-Cyclohex-3-enyl-propionic acid, Eicosanoic acid [3.3.1] 9,9-dimethyl-, nonane ,Dithiocarbamate , dl-Homocysteine, 2-(2-Furyl)pyridine, S-methyl-,N-(2-methyl-3-oxobutyl)-, ...
Looking for online definition of Antispasmodics in the Medical Dictionary? Antispasmodics explanation free. What is Antispasmodics? Meaning of Antispasmodics medical term. What does Antispasmodics mean?
Abstract Background Kinesin spindle proteins (KSP) are motor proteins that play an essential role in mitotic spindle formation. HsEg5, a KSP, is responsible for the formation of the bipolar spindle, which is critical for proper cell division during mitosis. The function of HsEg5 provides a novel target for the manipulation of the cell cycle and the induction of apoptosis. SB715992, an experimental KSP inhibitor, has been shown to perturb bipolar spindle formation, thus making it an excellent candidate for anti-cancer agent. Our major objective was a) to investigate the cell growth inhibitory effects of SB715992 on PC-3 human prostate cancer cell line, b) to investigate whether the growth inhibitory effects of SB715992 could be enhanced when combined with genistein, a naturally occurring isoflavone and, c) to determine gene expression profile to establish molecular mechanism of action of SB715992. Methods PC-3 cells were treated with varying concentration of SB715992, 30 μM of genistein, and SB715992
The 41 year old woman was an emergency admission in January 2004 with prolonged painful muscle spasms in her neck and back and arms and legs, rendering her bedridden and dependent on carers for months previously. She was taking baclofen and dantrolene sodium daily, fentanyl patches twice weekly and parenteral diazepam up to 80 mg and diamorphine up to 25 mg daily, providing subjective benefit.. The syndrome had been diagnosed in 2001. Various antispasmodic agents and disease modifying treatments, including seven courses of intravenous immunoglobulin and courses of cytotoxic drugs, tried since then had had no lasting success. Eventually, intrathecal infusions of hydrocortisone produced transient improvement, in December 2003.. However, after just over two weeks of rituximab at 375 mg/m3, in January 2004, muscle spasms started to subside, and the woman was able to sit up and shower herself for the first time in two years. Testing in November 2003 showed intrathecal autoantibody to GAD, but at 17 ...
Etienne Robillard 15:26, 5 February 2013 (EST): Thus, do you accept the spraying of humans with C(2)-phenoxy alkylamines reagents for the purpose of human genomic experiments, even such experiments were possibly lead by German scientists under the cover of your present or past government? And for what good reason do you assert "Synthetic Biology" is not a genuine indoctrination of your own consciousness, to let you not even objectify your own dissent agaisnt such human-specific experiments with psychotropic phenoxyalkylamine like alkyloids? . Lastly, do you object agaisnt militarisation of science and development of bioweapons by proceeding in unethical dual-purpose research to engineer virus-like particles (compounds) on the false likelyhood of "saving humanity" from X-Men attacks (ie flumageddon ...
It is not clear whether any benefits are sustained during long-term therapy or after discontinuing treatment, and there is no evidence of a clinically significant difference in efficacy among the various antimuscarinic drugs available today. Immediate-release non-proprietary oxybutynin, however, has been found to be the most cost-effective of theh options available. ...
NPI Number: 1003964594. Healthcare provider: DR. LYNETTE S JATTAN-CUNNINGHAM M.D.. Practice location address: 1277B WELLBROOK CIR NE CONYERS, GA, 30012-3873
Filanesib, also known as ARRY-520 is a synthetic, small molecule targeting the kinesin spindle protein (KSP) with potential antineoplastic activity. KSP inhibitor ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing. Because KSP is not involved in postmitotic processes, such as neuronal transport, this agent does not cause the peripheral neuropathy that is often associated with tubulin-targeting agents. KSP is an ATP-dependent microtubule motor protein that is essential for the formation of bipolar spindles and the proper segregation of sister chromatids during mitosis....
Novel cationic amphiphiles are provided that facilitate transport of biologically active (therapeutic) molecules into cells. The amphiphiles contain lipophilic groups derived from steroids, from mono or dialkylamines, or from alkyl or acyl groups; and cationic groups, protonatable at physiological pH, derived from amines, alkylamines or polyalkylamines. There are provided also therapeutic compositions prepared typically by contacting a dispersion of one or more cationic amphiphiles with the therapeutic molecules. Therapeutic molecules that can be delivered into cells according to the practice of the invention include DNA, RNA, and polypeptides. Representative uses of the therapeutic compositions of the invention include providing gene therapy, and delivery of antisense polynucleotides or biologically active polypeptides to cells. With respect to therapeutic compositions for gene therapy, the DNA is provided typically in the form of a plasmid for complexing with the cationic amphiphile. Novel and highly
The NPI Challenge for Medical Practices February 13, 2007. Discussion Points. Background The NPI Challenge Preparing for the NPI Recommendations Additional resources . Background. NPI Purpose. The purpose of the National Provider Identifier Slideshow 1456646 by uriel
University Pathology Associates, Pllc is provider located at Jackson MS. University Pathology Associates, Pllc NPI is 1518905124 and taxonomy code is 291U00000X.
Sari Kaplan-hasson PH.D. is physically located at New York NY. Sari Kaplan-hasson PH.D. npi is 1194025288 and taxonomy code is 103TC0700X.
The cell cycle proteins are key regulators of cell cycle progression whose de-regulation is one of the causes of breast cancer. RNA interference (RNAi) is an endogenous mechanism to regulate gene expression and it could serve as the basis of regulating aberrant proteins including cell cycle proteins. Since the delivery of small interfering RNA (siRNA) is a main barrier for implementation of RNAi therapy, we explored the potential of a non-viral delivery system, 2.0 kDa polyethylenimines substituted with linoleic acid and caprylic acid, for this purpose. Using a library of siRNAs against cell cycle proteins, we identified cell division cycle protein 20 (CDC20), a recombinase RAD51, and serine-threonine protein kinase CHEK1 as effective targets for breast cancer therapy, and demonstrated their therapeutic potential in breast cancer MDA-MB-435, MDA-MB-231 and MCF7 cells with respect to another well-studied cell cycle protein, kinesin spindle protein. We also explored the efficacy of dicer-substrate siRNA
Oxybutynin is an anticholinergic and antispasmodic agent that has been available in oral form since 1976 (originally as Ditropan) and in a topical patch form on a prescription basis since 2003.4,9 It relaxes bladder smooth muscle cells, which increases the maximum capacity of the bladder and also increases the volume to which the bladder fills before the patient begins to experience contractions of the detrusor muscle. The FDA approval of nonprescription Oxytrol For Women (oxybutynin transdermal system, 3.9 mg/day) marks the first time that women can purchase a nonprescription product for OAB. The product is identical to the prescription Oxytrol Patch.4. As with any newly released non-prescription product, pharmacists must take extra care in examining the label closely to understand all of the FDA-required safe conditions for use.4 Each patch contains a total of 36 mg of oxybutynin, delivering 3.9 mg of oxybutynin daily. The label instructs potential purchasers that they may have OAB if they ...
Dong Quai Botanical name(s): Angelica archangelica. Family: Umbelliferae Other name(s): angelica, Chinese angelica, Japanese angelica General description Dong quai is a fragrant perennial or biennial plant. It has greenish-white flowers. It is grown in Asia for medicinal purposes. In the U.S., its mostly used as a food flavoring. The roots and leaves are the parts of the plant that are used for medical reasons. Dong quai contains coumarins. These act as vasodilators and antispasmodic agents. One of the...
0096] 47.68 wt % of a material having molecular weight more than 150 and having a boiling point more than 200° C., among glycidyl ethers or glycol ethers, was used for a solvent. 13.38 wt % of diglycidyl ether of bisphenol-A having epoxy equivalent weight (EEW) of 184˜190(g/eq) was used for a first binder. 10.39 wt % of hydrogenated rosin was used for a second binder. The solvent, the first binder, and the second binder were stirred and dissolved under 100° C. 10.00 wt % of a condensation polymerized resin of phenol-melamine as a third binder and curing agent, 5 wt % of 3 or 4-methyl-1,2,3,6-tetrahydrophthalic anhydride as an acid anhydride-based curing agent, and 1.15 wt % of 2,4,6-tris(dimethylaminomethyl)phenol), which is tertiary amine based curing agent, as a curing accelerator were stirred and dissolved at a temperature under 100° C. After that, 0.15 wt % of ethylamine hydrobroimide, 0.25 wt % of butylamine hydrochloride, and 4.50 wt % of an adipic acid as active agents were heated ...
3,7-Dialkyl-8-alkyl- or -aryl-3,7-dihydropurine-2,6-diones XII-XIV were synthesized from 5-alkylamino-6-amino-1-alkyl-2,4(1H,3H)-pyrimidinediones VII-IX by three methods: the first is based upon an acid catalyzed cyclization of the starting derivatives VII-IX with orthoesters of carboxylic acids in dimethylformamide. In the second and third methods the 5-((N-acyl)(N-alkyl)amino) derivatives X, XI, obtained by acylation of VII-IX were cyclized either in aqueous solution of alkali metal hydroxides, or in dimethylformamide in the presence of alkali metal hydroxides, or in dimethylformamide in the presence of alkali metal carbonates. Intermediates VII-IX were prepared from 6-amino-1-alkyl-2,4(1H,3H)-pyrimidinediones I-III via the corresponding 5-bromo derivatives IV-VI and by their aminolysis with the appropriate alkylamines.. ...
Generic Antispasmodic drugs are used to treat symptoms such as pain and spasm in irritable bowel syndrome. Generic anti-spasmodic medication to reduce muscle spasms at discount from our pharmacy.
Definition of impinger in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is impinger? Meaning of impinger as a legal term. What does impinger mean in law?
[102 Pages Report] Check for Discount on Global Aliphatic Isocyanates Sales Market Report 2017 report by QYResearch Group. In this report, the global Aliphatic Isocyanates market is valued...
Vencorex announced that it is expanding the capacity for its aliphatic isocyanates product range, including HDI, IPDI, Tolonate and Easaqua grades, as well as new products. According to the company, several industrial projects will enhance its ability to serve the growing market for years to come.
1H-imidazo[4,5-c]quinoline which are bronchodilators. Pharmacological methods of using the compounds as bronchodilators, pharmaceutical compositions containing the compounds, and synthetic intermediat
Natamycin, dikenali sebagai pimaricin, yang biasa digunakan untuk pencegahan ragi dan acuan. Dan ia mudah ditambah kepada makanan untuk mencegah penyebaran yis dan cetakan dalam produk seperti keju, yogurt, minuman yogurt, daging yang diproses, jus, wain, sos dan bakar yang baik. Produk ini adalah aditif antimikrob ...
Executives increasingly see investing in retraining and “upskilling” existing workers as an urgent business priority that companies, not governments, must lead on.
samu SULPYRIN injection, an analgesicㆍantipyreticㆍantispasmodic of which main ingredient is Sulpyrin, one of Pyrazolone derivative, shows stronger fever alleviating effect about three times as much as Antipyrine and also has powerful action of analgesic and antiphlogistic ...
Combined preparations with barbiturates are mainly classified in A03 (mainly antispasmodic effect) or in N02 (mainly analgesic effect ...
NPI Number: 1477929420. Healthcare provider: URSULA L HOXIE APRN. Practice location address: 85 BARNES RD STE 202 WALLINGFORD, CT, 06492-1832
My view is that if you have to pay to get it that its a scam....any legit doctor that discovered a cure for this would make it available to everyone. Do you think if they ever come up with a cure for juvenile diabetes that only the ppl who could pay would have access to it? I think not ...
Alkyl Amines Chemicals Limited operates in the Chemicals & Allied Products sector. Alkyl Amines Chemicals Limited is engaged in the business of specialty chemicals. The Company is involved in the manufacture of organic and inorganic chemical compounds. Its products include Methylamine, Ethylamine, Isopropylamine, Propylamine, Butylamine, Ethylhexylamine, Cyclohexylamine, Diallylamine, Dimethylpropylamine, Di-Methylbutylamine, Mono-n-Butylamine, Diisobutylamine, Hydroxylnovaldiamine, Imino Bis Propylamine, Methylamine Hydrochloride and Dimethylimidazolidone. It supplies amines and amine-based chemicals to the pharmaceutical, agrochemical, rubber chemical and water treatment industries. It has approximately two manufacturing sites with over nine production plants and related utilities at Patalganga and Kurkumbh in Maharashtra. The Company caters to both domestic and international markets. It has various facilities to manufacture a range of specialty chemicals with its inhouse developed technologies.
Schématický akční srdeční potenciál (AP) s fázemi a hlavními odpovídajícími intovými proudy (A) Schematic cardiac action potential (AP) with phases and principal corresponding ion currents indicated. Red, inward (depolarizing) current; blue, outward (repolarizing) current. Horizontal lines at the bottom indicate the portions of the AP during which each current flows. IK1, inward-rectifier background K+ current; INa, Na+ current; Ito, transient-outward K+ current; IKs, slow delayed-rectifier K+ current; IKr, rapid delayed-rectifier K+ current; If, funny current (sometimes called pacemaker current because of its apparently important role in cardiac pacemaker function). (B) Various specialized tissues in the heart and typical corresponding APs. The short vertical lines indicate the time of onset of activity in the SA node for one beat. Green, slow-channel tissue (nodes); violet, fast-channel tissues. Michael G et al. Cardiovasc Res 2009;81: Published on behalf of the European
An antispasmodic herb suppresses spasms, and reduce muscular tension. Smooth muscles like those that line the stomach contract without conscious control, and cause spasms, cramp
Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a derivative thereof. Methods for treatment, prevention, or amelioration of one or more symptoms of bronchoconstrictive disorders using the compositions provided herein are also provided.
An anonymous reader writes Theres an interesting story on CNN about the University of Pennsylvanias human trial results on curing intractable cancer by retraining the patients own immune system. Quoting: Nick Wilkins was diagnosed with leukemia when he was 4 years old, and when the cancer kept ...
13. OCI Company Ltd. Analyses of the global Isocyanates market trends along with the projections of CAGRs (compound annual growth rates) are provided in the research report. To estimate the overall market size of Isocyanates, its application, and regions-in terms of value and volume-the bottom-up approach is followed. On the other hand, to corroborate the overall Isocyanates market size-again in terms of value and volume-the top-down approach is followed. Following the method of data triangulation and data validation via primaries, the precise values of the parent market and individual market in terms of size are calculated and established in the report.. This market research report provides the client with comprehensive market analysis of the Isocyanates market over the forecast period. In addition, it also furnishes a general idea of the challenges, drivers, and restraints that have direct or indirect impact on the industry. It further highlights the market, the industry, and latest technology ...
The design is prospective, randomized, controlled study. At baseline (during the first month), they will receive a standard training program on performing bag exchange and education on the prevention of peritonitis.. Then the participants will be randomized into three groups: retraining via operation inspection (G1), retraining via verbal education (G2) and usual care (G3). Retraining will be performed every 2 months in G1 and G2 group.. During the following 2 years or a longer period, all the participants will be followed up frequently with outcome events recorded. ...
"Tert-butylamine". Org. Synth. 27: 12. doi:10.15227/orgsyn.027.0012. CS1 maint: Uses authors parameter (link). ...
"Hydrogen oxidation catalysis by a nickel diphosphine complex with pendant tert-butyl amines". Chem. Commun.: 8618-8620. doi: ...
"Hydrogen oxidation catalysis by a nickel diphosphine complex with pendant tert-butyl amines". Chem. Commun.: 8618-8620. doi: ...
... is obtained by reaction of butylamine and 2-cyanoguanidine. Jacker, HJ (1964). "New Pharmacologic Products. 2. ...
Displacement of halogen by n-butylamine gives the antidepressant compound cartazolate. Displacement of halogen by the basic ...
The correct name after this style for this class of compound would be "phenylsecbutylamine". ...
Primary amines can be produced only after acidic hydrolysis of an intermediate tert-butylamine; the use of unsubstituted imines ...
Each tablet contains 2, 4, or 8 mg of the tert-butylamine salt of perindopril. Perindopril is also available under the trade ...
GB patent 995063, "A Substituted Butylamine and Salts thereof", issued 1965-06-10, assigned to Nordmark ...
... may refer to: sec-Butylamine (1-methylpropylamine) tert-Butylamine (2-methyl-2-propylamine) N- ...
... is a butylamine, chemically related to other ester local anesthetics such as procaine and tetracaine.[citation ...
Borane tert-butylamine complex is prepared by the reaction of sodium borohydride with t-butylammonium chloride. Generally ... Many analogues have been prepared from primary, secondary, and even tertiary amines: Borane tert-butylamine (tBuNH2→BH3) Borane ...
Each scored tablet contains 2 mg of perindopril tert-butylamine salt and 0.625 mg of indapamide. Essential hypertension. One ...
The molecular formula C4H11N may refer to: n-Butylamine sec-Butylamine tert-Butylamine Diethylamine N,N-Dimethylethylamine ...
Condensation of propionaldehyde with tert-butylamine gives CH3CH2CH=N-t-Bu, a three-carbon building block used in organic ...
... is one of the four isomeric amines of butane, the others being n-butylamine, sec-butylamine and tert-butylamine. ...
... with a primary amine like cyclohexylamine or tert-Butylamine. Secondary amines like dicyclohexylamine can be used also but ...
... which is reacted with N-benzyl-N-tert-butylamine, giving a ketone intermediate. Reduction of this product with H₂ over Pd/C ...
... and chlorobenzene with phenylacetylene using N-butylamine as base in THF solvent at 65 °C. Furthermore, all structural features ...
... (contracted from phenyl-tertiary-butylamine), also known as α,α-dimethylphenethylamine, is a psychostimulant drug ...
... butylamine, dimethylamine, trimethylphosphine oxide. New Jersey Department of Health. Thorium Nitrate. Hazardous Substance Fact ...
... can be synthesized from 2-bromoacetanilide via palladium-catalyzed carbonylation in tri-n-butylamine- ...
... for monitoring the reaction of epoxides with butylamine and predictive capabilities of the relative alkylation index (RAI) for ...
Initiation, Inhibition, Catalysis It was observed that N-chlorodi-n-butylamine was stable in 85% H2SO4 at 25 °C in the dark, ...
In this conversion, a dichloromethane solution of tert-butylamine is treated with chloroform and aqueous sodium hydroxide in ...
... *Formula: C14H31N. *Molecular weight: 213.4026 ...
... *Formula: C8H19N. *Molecular weight: 129.2432 ...
... *Formula: C4H12ClN. *Molecular weight: 109.598 ...
This colourless liquid is one of the four isomeric amines of butane, the others being sec-butylamine, tert-butylamine and ... At standard temperature and pressure, n-butylamine is a liquid having the fishy, ammonia-like odor common to amines. The liquid ... Butylamine is an organic compound, specifically, an amine. ... N-Butylamine. PDB Entries. 1ym2 / 4lkm. MSDS. Download (76.7 KB ... Butylamine. Accession Number. DB03659 (EXPT02080) Type. Small Molecule. Groups. Experimental. Description. Butylamine is an ...
sec-Butylamine was noted in milk of lactating cows and rabbits. sec-Butylamine is degraded by oxidative deamination to methyl ... There is no evidence that citrus is able to metabolize sec-butylamine in any way. An injection of 3 mg sec-butylamine as an ... The commercial product contains 25% sec-butylamine or 26% of the carbonate equivalent to 15.5% sec-butylamine. The product is ... See Also: Toxicological Abbreviations Butylamine, sec- (Pesticide residues in food: 1977 evaluations) Butylamine, sec- ( ...
p-Chlorobenzylidene-butyl-amine | C11H14ClN | CID 300876 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
sec-Butylamine is one of the four isomeric amines of butane, the others being n-butylamine, tert-butylamine and isobutylamine. ... sec-Butylamine is one of the isomers of butylamine. It is chiral and therefore can exist in either of two enantiomeric forms. ... sec-Butylamine is an organic chemical compound (specifically, an amine) with the formula CH3CH2CH(NH2)CH3, and occurs as a ... sec-Butylamine is used as a fungicide and is considered a high production volume chemical. It is undergoing comprehensive ...
This colourless liquid is one of the four isomeric amines of butane, the others being sec-butylamine, tert-butylamine, and ... Like other simple aliphatic amines, n-butylamine is a weak base: the pKa of [CH3(CH2)3NH3]+ is 10.78. This compound is used as ... It is produced by the reaction of ammonia and alcohols over alumina: CH3(CH2)3OH + NH3 → CH3(CH2)3NH2 + H2O n-Butylamine ... n-Butylamine is an organic compound (specifically, an amine) with the formula CH3(CH2)3NH2. ...
tert-Butylamine is one of the four isomeric amines of butane, the others being n-butylamine, sec-butylamine and isobutylamine. ... tert-Butylamine is an organic chemical compound with the formula (CH3)3CNH2. It is a colorless liquid with a typical amine-like ... tert-Butylamine is used as an intermediate in the preparation of the sulfenamides such as N-tert-butyl-2- ... tert-Butylamine is produced commercially by the Ritter reaction of isobutene with hydrogen cyanide under acidic conditions to ...
Lirnac information about active ingredients, pharmaceutical forms and doses by Ranbaxy, Lirnac indications, usages and related health products lists
Borane tert-butylamine (TBAB) is an amine borane complex derived from tert-butylamine and borane. It is a colorless solid. The ... "t-Butylamine Borane (TBAB)" (PDF). Technical Datasheet. BASF. [permanent dead link]. ...
tert.butyl amine salt of (+)-(3R, 5S)-7[4-(4-Fluorophenyl)-6- Isopropyl-2 [methyl-(methyl sulfonyl amino] pyrimidin-5- yl]-3,5 ... tert.butyl amine salt of (+)-(3R, 5S)-7[4-(4-Fluorophenyl)-6-Isopropyl-2 [methyl-(methylsulfonyl amino] pyrimidin-5-yl]-3,5- ... tert.butyl amine salt of (+)-(3R, 5S)-7[4-(4-Fluorophenyl)-6-Isopropyl-2 [methyl-(methylsulfonyl amino] pyrimidin-5-yl]-3,5- ...
Butylamine-copper complex formation. Pipette being used to add butylamine to a solution of copper ions. The hydrated copper ... while the dark blue colour above this is due to the formation of a complex between the copper and the butylamine. - Stock Image ... Butylamine-copper complex formation. Pipette being used to add butylamine to a solution of copper ions. The hydrated copper ... Keywords: amine, blue, butylamine, caucasian, chemical, chemistry, complex, copper sulphate, experiment, experimenting, hand, ...
2-Butylamine;sec-C4H9NH2;sec-Butanamine;Deccotane;Frucote;2-Aminobutane base;(Rs)-2-aminobutane;(Rs)-sec-butylamine;Secondary ... Laboratory testing for CAS number 13952-84-6. sec-Butylamine;Butafume;Propylamine, 1-Methyl-;Tutane;1-Methylpropanamine;1- ... butylamine;CSC 2-Aminobutane. This chemical is colourless liquid with an amine odour ... sec-Butylamine - CAS # 13952-84-6. Information provided on sec-Butylamine (13952-84-6) is for reference only and is subject to ...
Tert-Butylamine market situation is overviewed; tert-butylamine ... The report generally describes tert-butylamine, examines its ... Tert-butylamine market forecast. 6. TERT-BUTYLAMINE MARKET PRICES. 6.1. Tert-butylamine prices in Europe. 6.2. Tert-butylamine ... Tert-butylamine prices in North America. 6.4. Tert-butylamine prices in other regions. 7. TERT-BUTYLAMINE END-USE SECTOR 7.1. ... Tert-butylamine application spheres, downstream products. 3. TERT-BUTYLAMINE MANUFACTURING METHODS. 4. TERT-BUTYLAMINE PATENTS ...
Butylamine and o-phthaldialdehyde have been used as derivatization reagents. Since o-phthaldialdehyde constitutes a part of the ... Butylamine and o-phthaldialdehyde have been used as derivatization reagents. Since o-phthaldialdehyde constitutes a part of the ... Application of Butylamine as a Conjugative Reagent to On-Column Derivatization for the Determination of Antioxidant Amino Acids ... "Application of Butylamine as a Conjugative Reagent to On-Column Derivatization for the Determination of Antioxidant Amino Acids ...
Tert-Butylamine is one of the four isomeric amines of butane, the others being n-butylamine, sec-butylamine and isobutylamine. ... Tert-Butylamine is an organic chemical compound with the formula (CH3)3CNH2. It is a colorless liquid with a typical amine-like ... Global tert-Butylamine (CAS 75-64-9) Market Outlook 2016-2021, has been prepared based on the synthesis, analysis, and ... Global tert-Butylamine (CAS 75-64-9) Market Outlook 2016 Industry Growth, Trends, Size, Share and Analysis by 2021. ...
BASF has increased production of tertiary Butylamine (tBA) at its manufacturing plant at Nanjing Chemical Industry Park in ...
Global demand for tert-Butylamine market was valued at USD 200.0 million in 2014, is expected to reach USD 295.92 million in ... Growth of tert-Butylamine in Asia Pacific has been mainly driven by the extensive use of tert-Butylamine by end-user industries ... In terms of volume, the global tert-Butylamine market stood at 50,000.0 tons in 2014.. tert-Butylamine (tBA) is a primary ... However, chemical synthesis is a fast growing application of tert-Butylamine.. The global tert-Butylamine market was dominated ...
VASCULAR DILATOR ACTION OF t-BUTYLAMINE AND ITS DEPENDENCE ON SYMPATHETIC TONE. Thomas Baum and Donald R. Bennett ... VASCULAR DILATOR ACTION OF t-BUTYLAMINE AND ITS DEPENDENCE ON SYMPATHETIC TONE. Thomas Baum and Donald R. Bennett ... VASCULAR DILATOR ACTION OF t-BUTYLAMINE AND ITS DEPENDENCE ON SYMPATHETIC TONE. Thomas Baum and Donald R. Bennett ... VASCULAR DILATOR ACTION OF t-BUTYLAMINE AND ITS DEPENDENCE ON SYMPATHETIC TONE ...
2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine ...
Ligand substitution reactions of W6S8L6 with tricyclohexylphosphine (L=4-tert-butylpyridine or n-butylamine): P-31 NMR and ... Ligand substitution reactions of W6S8L6 with tricyclohexylphosphine (L=4-tert-butylpyridine or n-butylamine): P-31 NMR and ...
Measured Gas: N-Butyl Amine Tube Number: 105SD. Range: 1-20 ppm. Tubes Per Box: 10 TUBES. Download N-Butyl Amine Detector Tube ... Colorimetric N-Butyl Amine 1-20 ppm Gas Detector Tube. The Sensidyne Gas Detector Tube System and N-Butyl Amine 1-20 ppm Gas ... The N-Butyl Amine 1-20 ppm Gas Detector Tube System is perfect when sampling for N-Butyl Amine or literally hundreds of other ... N-Butyl Amine 1-20 ppm Gas Detector Tube. Sensidyne Gas Detector Tubes ...
  • Global tert-Butylamine (CAS 75-64-9) Market Outlook 2016-2021, has been prepared based on the synthesis, analysis, and interpretation of information about the global tert-Butylamine (CAS 75-64-9) market collected from specialized sources. (pitchengine.com)
  • Deerfield Beach, FL -- ( SBWIRE ) -- 02/01/2016 -- Zion Research has published a new report titled " Global and China tert-Butylamine (CAS 75-64-9) Market for Rubber Industry, Pharmaceuticals, Agrochemicals and Other (Chemical Synthesis, etc. (sbwire.com)
  • Browse the full Global and China tert-Butylamine (CAS 75-64-9) Market for Rubber Industry, Pharmaceuticals, Agrochemicals and Other (Chemical Synthesis, etc. (sbwire.com)
  • tert-Butylamine has a vast range of applications and is used as a chemical intermediate in the manufacturing of a variety of agrochemical and pharmaceutical formulations and chemical synthesis. (sbwire.com)
  • However, chemical synthesis is a fast growing application of tert-Butylamine. (sbwire.com)
  • Condensation of propionaldehyde with tert-butylamine gives CH3CH2CH=N-t-Bu, a three-carbon building block used in organic synthesis. (wikipedia.org)
  • In one illustrative synthesis, triphenylmethanesulphenyl chloride and butylamine react in benzene at 25 C: Ph3CSCl + 2BuNH2 → Ph3CSN(H)Bu + BuNH3Cl Many other routes to sulfenamides are known, starting from thiols and disulfides. (wikipedia.org)
  • Rabbit Groups of rabbits were fed sec -butylamine phosphate in the diet and subjected to a two generation, one litter per generation reproduction study. (inchem.org)
  • The F1a were maintained for six months, divided into groups of 6 males and 12 females, fed 2500 ppm sec -butylamine phosphate with 5 males and 8 females fed control diets. (inchem.org)
  • 4H2O are also known Thorium nitrate also crystallizes with other ligands and organic solvates incliding ethylene glycol diethyl ether, tri(n‐butyl)phosphate, butylamine, dimethylamine, trimethylphosphine oxide. (wikipedia.org)
  • In this conversion, a dichloromethane solution of tert-butylamine is treated with chloroform and aqueous sodium hydroxide in the presence of catalytic amount of the phase transfer catalyst benzyltriethylammonium chloride. (wikipedia.org)
  • BASF has increased production of tertiary Butylamine (tBA) at its manufacturing plant at Nanjing Chemical Industry Park in China. (chemicals-technology.com)
  • Phentermine (contracted from phenyl-tertiary-butylamine), also known as α,α-dimethylphenethylamine, is a psychostimulant drug of the substituted amphetamine chemical class, with pharmacology similar to amphetamine. (wikipedia.org)
  • TOXICOLOGICAL STUDIES Special studies on pharmacological response Groups of dogs were administered sec -butylamine as the carbonate or acetate salt and data were recorded an heart rate, respiration rate, blood pressure and with an EEG apparatus. (inchem.org)
  • Growth of tert-Butylamine in Asia Pacific has been mainly driven by the extensive use of tert-Butylamine by end-user industries such as rubber, pharmaceuticals, crop protection chemicals and increasing chemicals industry in the region. (sbwire.com)
  • The hydrated copper ions give the light blue colour seen at the bottom of the test tube, while the dark blue colour above this is due to the formation of a complex between the copper and the butylamine. (sciencephoto.com)
  • The bromide in 2 is then displaced by the nitrogen in N-benzyl-1-(3',4'-methylenedioxyphenyl)-3-butylamine (3), which is itself prepared by reductive amination on the corresponding ketone. (wikipedia.org)
  • The carcinogen N‐Nitrosodi-n-butylamine has been measured in soybean oil at a concentration of 290 μg/kg, in cheese at 20 to 30 μg/kg, and in smoked or cured meats at up to 3.9 μg/kg. (wikipedia.org)
  • Residues of sec -butylamine were found in muscle, liver, fat and kidney in a dose relationship at 100 and 10 ppm (but not 2 ppm) levels in the diet fed to cows for up to 28 days. (inchem.org)
  • The residues were found in samples taken at 0 withdrawal time after feeding (animals were fed diets containing sec -butylamine until sacrificed). (inchem.org)
  • Furthermore, tert-butylamine prices in regional markets can be found in the report with regards to countries and companies. (marketpublishers.com)
  • The 'Global and Chinese N,N-Dimethyl-butylamine Industry, 2012-2022 Market Research Report' is a professional and in-depth study on the current state of the global N,N-Dimethyl-butylamine industry with a focus on the Chinese market. (researchbeam.com)
  • It covers the key technological and market trends in the tert-Butylamine (CAS 75-64-9) market and further lays out an analysis of the factors influencing the supply/demand for tert-Butylamine (CAS 75-64-9), and the opportunities/challenges faced by industry participants. (pitchengine.com)
  • In this sector, global competitive landscape and supply/demand pattern of tert-Butylamine (CAS 75-64-9) industry has been provided. (pitchengine.com)
  • Applications, 2014 - 2020 report at http://www.marketresearchstore.com/report/global-and-china-tert-butylamine-market-for-34818 tert-Butylamine is widely used as a accelerator in rubber industry. (sbwire.com)
  • The report provides key statistics on the market status of the N,N-Dimethyl-butylamine manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry.Firstly, the report provides a basic overview of the industry including its definition, applications and manufacturing technology. (researchbeam.com)
  • The report then estimates 2017-2022 market development trends of N,N-Dimethyl-butylamine industry. (researchbeam.com)
  • In the end, the report makes some important proposals for a new project of N,N-Dimethyl-butylamine Industry before evaluating its feasibility. (researchbeam.com)
  • Overall, the report provides an in-depth insight of 2012-2022 global and Chinese N,N-Dimethyl-butylamine industry covering all important parameters. (researchbeam.com)
  • This report provides detailed analysis of worldwide markets for tert-Butylamine (CAS 75-64-9) from 2011-2016, and provides extensive market forecasts (2016-2021) by region/country and subsectors. (pitchengine.com)