Scleredema Adultorum: A diffuse, non-pitting induration of the skin of unknown etiology that occurs most commonly in association with diabetes mellitus, predominantly in females. It typically begins on the face or head and spreads to other areas of the body, sometimes involving noncutaneous tissues. Often it is preceded by any of various infections, notably staphylococcal infections. The condition resolves spontaneously, usually within two years of onset. (From Dorland, 27th ed)Mycobacterium tuberculosis: A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation.Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Tumor Burden: The total amount (cell number, weight, size or volume) of tumor cells or tissue in the body.Tumor Necrosis Factor-alpha: Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.Cell Line, Tumor: A cell line derived from cultured tumor cells.Wilms Tumor: A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.Medical Oncology: A subspecialty of internal medicine concerned with the study of neoplasms.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Buschke-Lowenstein Tumor: Exophytic tumor of the anogenital region associated with HPV infections. It becomes a large cauliflower-like, hyperkeratotic, verrucous mass that is locally destructive with little atypical cells. Histologically, tumor cells are broad rete peg structures that tend to invade deeper than CONDYLOMATA ACUMINATA.Condylomata Acuminata: Sexually transmitted form of anogenital warty growth caused by the human papillomaviruses.Dictionaries, MedicalDictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Rare Diseases: A large group of diseases which are characterized by a low prevalence in the population. They frequently are associated with problems in diagnosis and treatment.Self-Help Groups: Organizations which provide an environment encouraging social interactions through group activities or individual relationships especially for the purpose of rehabilitating or supporting patients, individuals with common health problems, or the elderly. They include therapeutic social clubs.Feminism: The theory of the political, economic, and social equality of the sexes and organized activity on behalf of women's rights and interests. (Webster New Collegiate Dictionary, 1981)Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Drug Approval: Process that is gone through in order for a drug to receive approval by a government regulatory agency. This includes any required pre-clinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance of the drug.United States Food and Drug Administration: An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Podophyllin: Caustic extract from the roots of Podophyllum peltatum and P. emodi. It contains PODOPHYLLOTOXIN and its congeners and is very irritating to mucous membranes and skin. Podophyllin is a violent purgative that may cause CNS damage and teratogenesis. It is used as a paint for warts, skin neoplasms, and senile keratoses.Genital Neoplasms, Male: Tumor or cancer of the MALE GENITALIA.Anus DiseasesPenile Neoplasms: Cancers or tumors of the PENIS or of its component tissues.Dictionaries, ChemicalCell Cycle: The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.Terminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.

Buschke -Loewenstein tumor: identification of HPV type 6 and 11. (1/4)


Comprehensive analysis of human papillomavirus prevalence and the potential role of low-risk types in verrucous carcinoma. (2/4)


Buschke-Lowenstein Tumor. (3/4)

INTRODUCTION: Giant condyloma acuminatum belongs to a spectrum of diseases with malignant degeneration. Clinically, it presents as exophytic, fungating masses, sometimes with a cauliflower-like morphology. CASE PRESENTATION: We present a case of a 32-year-old female patient with a 180x95x80mm exophytic mass of the vulvar region suggestive of Buschke-Lowenstein Tumour. Treatment included wide local excision with electrosurgery and CO2 vaporization of recurrent focal lesions. Histopathological analysis confirmed the expected diagnosis. Surgery went without complications and the patient is lesion-free at the 12th month of follow-up. CONCLUSION: There is a lack of consistent trials regarding optimal treatment of BLT. Surgery, when feasible, remains the mainstay of treatment. It allows quick lesion size reduction, with fewer side effects and more rapid return to daily living activities, when compared to other treatment options.  (+info)

Buschke-Lowenstein tumor with squamous cell carcinoma treated with chemo-radiation therapy and local surgical excision: report of three cases. (4/4)


  • The pathology of head and neck tumors: Unfortunately, long-term remission rates remain largely unknown, and the majority of genital warts will recur within three months of infection, even after undergoing the appropriate treatments. (
  • It was hard in consistency and gave the look of a bulky tumor. (
  • Clinically, the tumor appears as a rather bulky mass, budding, of cauliflower aspect, which evolves in surface and in depth. (
  • Bulky tumors have been shrunk with preoperative chemoradiation, followed by radical surgery, in some instances followed by reconstructive surgery. (
  • This often-aggressive tumor phenotype has been characterized by its poor prognosis, mostly attributable to its late presentation and heterogeneity of surgical care because of the paucity of cases treated at most centers. (
  • CGA concentration correlates with tumor volume, and it may be useful for staging, prognosis, and monitoring response to therapy. (
  • Se presentó un paciente masculino de 68 años, que acudió a consulta de Dermatología por presentar lesiones vegetantes en coliflor en región inguinal izquierda, pubis y perineales, de 10 años de evolución y nunca tratadas. (
  • however, an inguinal tumor was diagnosed intraoperatively and was resected as much as possible. (
  • Sacral resection en bloc and anus praeter were performed following radiotherapy treatment. (
  • The pathology report should include tumor diameter, tumor thickness, and whether the following tissues are infiltrated: Lamina propria, corpus spongiosum, urethra, and preputium, and whether resection borders are free of tumor. (
  • El tumor de Buschke-Löwenstein o condiloma acuminado gigante es una tumoración epitelial benigna, causada por el virus del papiloma humano, trasmisible sexualmente, en raros casos puede malignizar. (
  • O tumor de Buschke-Löwenstein ou o condiloma acuminado gigante é um tumor epitelial benigno, causado pelo papilomavírus humano sexualmente transmissível, podendo, em casos raros, malignizar. (
  • One case report noted that intralesional bleomycin in the wound bed of an incompletely resected tumor was effective, with no recurrence at 2 years. (
  • At the deep aspect of the biopsy specimen, tumor cells intercalated between collagen bundles in linear strands. (
  • Histopathological evaluation (with the use of ancillary studies, including immunohistochemical stains for neuroendocrine markers, if necessary) of the removed tumor or biopsy material confirms the diagnosis. (
  • In 1894 with pathologist Otto Busse (1867-1922), Buschke described an infectious disease caused by the fungus Cryptococcus neoformans. (
  • In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. (
  • Tumor cells can be carried throughout the body in the bloodstream or in the lymph and can settle in various organs and tissues, forming metastases. (
  • [ 1 ] Even when the tumor is large, when it has been present for many years, and when it penetrates the bone, distant metastases are rare. (
  • With the history of colon cancer, radiation treatment, and chemotherapy, the possible malignancy diagnoses included primary skin cancers, viral tumors, and cutaneous metastasis. (
  • Although the tumors are slow growing with little risk for metastasis, they may be locally invasive with deep involvement of the surrounding structures. (
  • Tipos de Virus del Papiloma Humano Alto y bajo riesgo testicular cancer with normal tumor markers Cea mai mare prevalenţă s-a întâlnit la bărbaţii HIV-pozitivi care au relaţii sexuale cu alţi bărbaţi. (
  • Virus papiloma humano numero 16 Tipos de Virus del Papiloma Humano Alto y bajo riesgo testicular cancer with normal tumor markers Papillomaviridae papilomas papilloma removal recovery, planters wart on foot apple cider vinegar oxiuros caracteristicas. (