Scleredema Adultorum: A diffuse, non-pitting induration of the skin of unknown etiology that occurs most commonly in association with diabetes mellitus, predominantly in females. It typically begins on the face or head and spreads to other areas of the body, sometimes involving noncutaneous tissues. Often it is preceded by any of various infections, notably staphylococcal infections. The condition resolves spontaneously, usually within two years of onset. (From Dorland, 27th ed)Mycobacterium tuberculosis: A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation.Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Tumor Burden: The total amount (cell number, weight, size or volume) of tumor cells or tissue in the body.Tumor Necrosis Factor-alpha: Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.Cell Line, Tumor: A cell line derived from cultured tumor cells.Wilms Tumor: A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.Medical Oncology: A subspecialty of internal medicine concerned with the study of neoplasms.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Buschke-Lowenstein Tumor: Exophytic tumor of the anogenital region associated with HPV infections. It becomes a large cauliflower-like, hyperkeratotic, verrucous mass that is locally destructive with little atypical cells. Histologically, tumor cells are broad rete peg structures that tend to invade deeper than CONDYLOMATA ACUMINATA.Condylomata Acuminata: Sexually transmitted form of anogenital warty growth caused by the human papillomaviruses.Dictionaries, MedicalDictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Rare Diseases: A large group of diseases which are characterized by a low prevalence in the population. They frequently are associated with problems in diagnosis and treatment.Self-Help Groups: Organizations which provide an environment encouraging social interactions through group activities or individual relationships especially for the purpose of rehabilitating or supporting patients, individuals with common health problems, or the elderly. They include therapeutic social clubs.Feminism: The theory of the political, economic, and social equality of the sexes and organized activity on behalf of women's rights and interests. (Webster New Collegiate Dictionary, 1981)Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Drug Approval: Process that is gone through in order for a drug to receive approval by a government regulatory agency. This includes any required pre-clinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance of the drug.United States Food and Drug Administration: An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Podophyllin: Caustic extract from the roots of Podophyllum peltatum and P. emodi. It contains PODOPHYLLOTOXIN and its congeners and is very irritating to mucous membranes and skin. Podophyllin is a violent purgative that may cause CNS damage and teratogenesis. It is used as a paint for warts, skin neoplasms, and senile keratoses.Genital Neoplasms, Male: Tumor or cancer of the MALE GENITALIA.Anus DiseasesPenile Neoplasms: Cancers or tumors of the PENIS or of its component tissues.Dictionaries, ChemicalCell Cycle: The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.Terminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.Balanitis Xerotica Obliterans: An atrophic and sclerotic condition of the head of the PENIS, glans penis. Sometimes it leads to stenosis and occasionally obliteration of the external meatal orifice.Balanitis: Inflammation of the head of the PENIS, glans penis.Lichen Sclerosus et Atrophicus: A chronic inflammatory mucocutaneous disease usually affecting the female genitalia (VULVAR LICHEN SCLEROSUS) and BALANITIS XEROTICA OBLITERANS in males. It is also called white spot disease and Csillag's disease.Phimosis: A condition in which the FORESKIN cannot be retracted to reveal the GLANS PENIS. It is due to tightness or narrowing of the foreskin opening.Vulvar Lichen Sclerosus: Atrophy and shriveling of the SKIN of the VULVA that is characterized by the whitish LICHEN SCLEROSUS appearance, inflammation, and PRURITUS.Penis: The external reproductive organ of males. It is composed of a mass of erectile tissue enclosed in three cylindrical fibrous compartments. Two of the three compartments, the corpus cavernosa, are placed side-by-side along the upper part of the organ. The third compartment below, the corpus spongiosum, houses the urethra.Penile Diseases: Pathological processes involving the PENIS or its component tissues.Carcinoma, Transitional Cell: A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS.Search Engine: Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)Anal Canal: The terminal segment of the LARGE INTESTINE, beginning from the ampulla of the RECTUM and ending at the anus.Anus, Imperforate: A congenital abnormality characterized by the persistence of the anal membrane, resulting in a thin membrane covering the normal ANAL CANAL. Imperforation is not always complete and is treated by surgery in infancy. This defect is often associated with NEURAL TUBE DEFECTS; MENTAL RETARDATION; and DOWN SYNDROME.Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.Carcinoma, Verrucous: A variant of well-differentiated epidermoid carcinoma that is most common in the oral cavity, but also occurs in the larynx, nasal cavity, esophagus, penis, anorectal region, vulva, vagina, uterine cervix, and skin, especially on the sole of the foot. Most intraoral cases occur in elderly male abusers of smokeless tobacco. The treatment is surgical resection. Radiotherapy is not indicated, as up to 30% treated with radiation become highly aggressive within six months. (Segen, Dictionary of Modern Medicine, 1992)BrazilMaxillary Neoplasms: Cancer or tumors of the MAXILLA or upper jaw.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.San FranciscoHirschsprung Disease: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.Urogenital Abnormalities: Congenital structural abnormalities of the UROGENITAL SYSTEM in either the male or the female.Ependymoma: Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)Sacrum: Five fused VERTEBRAE forming a triangle-shaped structure at the back of the PELVIS. It articulates superiorly with the LUMBAR VERTEBRAE, inferiorly with the COCCYX, and anteriorly with the ILIUM of the PELVIS. The sacrum strengthens and stabilizes the PELVIS.Teratoma: A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)

Buschke -Loewenstein tumor: identification of HPV type 6 and 11. (1/4)

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Comprehensive analysis of human papillomavirus prevalence and the potential role of low-risk types in verrucous carcinoma. (2/4)

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Buschke-Lowenstein Tumor. (3/4)

INTRODUCTION: Giant condyloma acuminatum belongs to a spectrum of diseases with malignant degeneration. Clinically, it presents as exophytic, fungating masses, sometimes with a cauliflower-like morphology. CASE PRESENTATION: We present a case of a 32-year-old female patient with a 180x95x80mm exophytic mass of the vulvar region suggestive of Buschke-Lowenstein Tumour. Treatment included wide local excision with electrosurgery and CO2 vaporization of recurrent focal lesions. Histopathological analysis confirmed the expected diagnosis. Surgery went without complications and the patient is lesion-free at the 12th month of follow-up. CONCLUSION: There is a lack of consistent trials regarding optimal treatment of BLT. Surgery, when feasible, remains the mainstay of treatment. It allows quick lesion size reduction, with fewer side effects and more rapid return to daily living activities, when compared to other treatment options.  (+info)

Buschke-Lowenstein tumor with squamous cell carcinoma treated with chemo-radiation therapy and local surgical excision: report of three cases. (4/4)

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Looking for Buschke-Lowenstein tumor? Find out information about Buschke-Lowenstein tumor. see neoplasm neoplasm or tumor, tissue composed of cells that grow in an abnormal way. Normal tissue is growth-limited, i.e., cell reproduction is equal to... Explanation of Buschke-Lowenstein tumor
In the early 2000s the concept of tumour treating fields came up. Tumour treating fields is exposing cells to an electrical field with an electrical potential. This causes polar molecules to arrange themselves in the direction of the field. If you start rotating the field many times you actually have the cells or the organelles in the cells, the polar molecules, to redirect according to the field and this has been shown in vitro and also in animal models to actually ultimately lead to disruption of the spindle apparatus and mitosis and ultimately apoptosis.. What were you looking at in your research?. In our research now we had to design a clinical trial that would definitely show that this is working also in the clinic. So the trial Im presenting here is on patients with newly diagnosed glioblastoma who have completed chemo-radiation therapy and would go for maintenance temozolomide chemotherapy to which we added in one arm tumour treating fields. Patients were exposed to it continuously, so ...
PRIMARY OBJECTIVES:. I. To determine if post-operative adjuvant chemo-radiation therapy (CRT) can significantly improve recurrence-free survival (RFS) when compared to radiation therapy (RT) alone in stage I-IIA cervical cancer patients with intermediate-risk factors after treatment with radical hysterectomy.. SECONDARY OBJECTIVES:. I. To determine whether post-operative adjuvant CRT can improve overall survival (OS) when compared to RT alone in stage I-IIA cervical cancer patients with intermediate risk factors after treatment with radical hysterectomy.. II. To assess differences (across treatment arms) in incidence and severity of therapy-attributed adverse events utilizing the active version of Common Terminology Criteria for Adverse Events (CTCAE).. III. To provide assessment of patient risk vs benefit (positive study only). IV. To determine whether post-operative adjuvant CRT improves the health-related quality-of-life (QOL) (compared to RT alone) as measured by Functional Assessment of ...
PRIMARY OBJECTIVES:. I. To determine if post-operative adjuvant chemo-radiation therapy (CRT) can significantly improve recurrence-free survival (RFS) when compared to radiation therapy (RT) alone in stage I-IIA cervical cancer patients with intermediate-risk factors after treatment with radical hysterectomy.. SECONDARY OBJECTIVES:. I. To determine whether post-operative adjuvant CRT can improve overall survival (OS) when compared to RT alone in stage I-IIA cervical cancer patients with intermediate risk factors after treatment with radical hysterectomy.. II. To assess differences (across treatment arms) in incidence and severity of therapy-attributed adverse events utilizing the active version of Common Terminology Criteria for Adverse Events (CTCAE).. III. To provide assessment of patient risk vs benefit (positive study only). IV. To determine whether post-operative adjuvant CRT improves the health-related quality-of-life (QOL) (compared to RT alone) as measured by Functional Assessment of ...
The purpose of the study is to investigate if treatment with zalutumumab in combination with chemotherapy and radiotherapy (chemo-radiation) will lead t
407 The majority of patients with non-small cell lung cancer (NSCLC) are diagnosed with advanced disease confined to the chest that is technically unresectable. These patients have a poor prognosis with a median survival of approximately one year. In patients treated with surgery and pre-operative chemo-radiation, median survival improves to 15-17 months due mostly to improved local control. It is thus possible that by sensitizing tumors to definitive chemo-radiation, the same improvement in survival could be seen. We know that mutations in EGFR and Ras are seen in 70% and 20-30% of patients with NSCLC respectively. Both of these have been shown to result in a poorer outcome and resistance to radiation. Erlotnib is currently being used in patients with NSCLC. We have seen that radiation resistance can be abrogated by down-regulation of EGFR but only when it results in downregulation of Akt. Previous studies in NSCLC have found the frequency of Akt activation to range between 67-83%. Nelfinavir, ...
It is well-established that nasopharyngeal carcinoma (NPC) is a chemo-responsive disease. Despite improved outcome with chemo-radiation (platimum-based chemotherapy with radiation), treatment failure continue to be a problem in patients with locally advanced Stage III/IV disease. Now, a new study published … Continue reading →. ...
The primary form of treatment is local surgical excision. Mohs surgery is a specialized technique which may determine the local invasion of the melanoma more accurately. CAT scans and MRI scans are imaging studies which are often obtained to check for distant spread of the tumor.. Since melanoma usually spreads through the lymph system a new type of test called lymphoscintigraphy is sometimes used. A small amount of a radioactive substance is injected around the tumor and nearby lymph nodes are then surgically removed to check for tumor spread. If the "sentinal" node shows no tumor then its felt that the tumor has not spread to other parts of the body.. Chemotherapy is not highly effective in the treatment of melanoma. Interferon ,a substance which can stimulate an immune response in the body may hold some promise. Vaccine research is also ongoing but not yet available. Obviously the best treatment remains prevention and early detection.. ...
Journal of the American Academy of Dermatology - Vol. 57 - N° 3 - p. 516-519 - Photodynamic therapy for cutaneous verrucous carcinoma - EM|consulte
Daily low-dose carboplatin with concurrent radiotherapy yielded better survival results in elderly non-small cell lung cancer patients with advanced disease compared with radiotherapy alone, according
Denise Tostes Oliveira, Renato Vieira de Moraes, Jorge Francisco Fiamengui Filho, João Fanton Neto, Gilles Landman, Luiz Paulo Kowalski
DESCRIPTION (provided by applicant): This project will evaluate a non-invasive PET method for assessment of tumor perfusion using generator- produced copper-62. The proposed method will be suitable for implementation at any clinical PET center in the U.S., complementing current clinical whole-body PET 18F-FDG studies to assess tumor metabolism. The projects clinical focus is patients with head-and-neck cancer, where literature evidence indicates that tumor perfusion measurements can be predictive of response to therapy. Patients with localized or locally advanced head and neck cancer, who are to receive concurrent chemo-radiation therapy, will receive the investigational 62Cu-ETS radiopharmaceutical for "whole-body" PET/CT imaging to assess tumor perfusion. The 62Cu-ETS imaging will occur immediately prior to scheduled standard baseline and post-therapy clinical PET/CT with 18F-FDG. A subset of patients will also be imaged using 15O-water to provide an independent reference measure of tumor ...
Verrucous carcinoma is a variant of squamous cell carcinoma (SCCA). In the head and neck, this uncommon subtype of SCCA is seen most often in the oral cavity or on the vocal cords. Visually, it tends to have an exophytic (outward-growing) and wartlike, irregular surface. This variant of SCCA is typically less aggressive than other squamous cell carcinomas. Local recurrence tends to be the issue more than distant metastasis. Surgery tends to be the most effective treatment, though of course every patients circumstance is individualized and considered in the light of three treatment options: surgery, radiation therapy, and chemotherapy.. ...
DI-fusion, le Dépôt institutionnel numérique de lULB, est loutil de référencementde la production scientifique de lULB.Linterface de recherche DI-fusion permet de consulter les publications des chercheurs de lULB et les thèses qui y ont été défendues.
Back in 2016 I was diagnosed with a rare form of Bowel Cancer, there were only 2 cases of it at the hospital where I was under. My Oncologist explained all the details about the diagnosis but I think I found out more by doing my own research. As a part of my treatment I was offered chemo-radiation, this is a treatment that means I was to have radiotherapy alongside taking chemotherapy tablets.. Radiotherapy is the use of controlled, high - energy radiation. It is offered alongside chemotherapy as it makes the cancerous cells more sensitive to the radiation.. I was told that I would have radiotherapy first to try to shrink the tumour before surgery, as this would make it easier for the surgeon to remove it. My tumor measured at 3 cms and was close to my rectum, sitting on the sphincter muscle - which controlled the movement of the bowel. The tumor was very close to the skin, so close that it could be felt from the outside.. From receiving my diagnosis til the first day of my radiotherapy it took ...
Swallowing dysfunction after chemo-radiation is common, but there is no reliable evidence for how it should be managed. This pilot randomized controlled
How to Cite: Rishard, M., Ranaweera, A., Seneviratne, H., Kaluarachchi, A. and Abeygunawardane, D., 2012. A rare case of verrucous carcinoma of the cervix in a patient with uterine prolapse. Sri Lanka Journal of Obstetrics and Gynaecology, 34(1), pp.19-20. DOI: http://doi.org/10.4038/sljog.v34i1.4817 ...
A 42 year old male requested telemedicine consultation for treatment of glioblastoma. He developed unremitting headaches was diagnosed with a grade 2 right parietal oligodendroglioma about 2 years prior to consulting us. This was treated initially with surgical debulking (90% of the tumour was removed).. Due to re-growth 1 year after surgery, he was treated with temozolamide chemotherapy, with good initial results. After 7 cycles of temozolamide, the tumour began to re-grow.. The patient was then treated with chemo-radiation (combination temozolamide + radiation). He improved initially after this treatment, but was not given any good options for further treatment in the event of new growth. At that time, an MRI showed the tumour way 6.5cm in its maximum dimension (anterior-posterior). There was a notation in the report of possible increase in contrast enhanced material within tumour suggesting early re-growth after chemo-radiation.. He then consulted us about novel treatment approaches.. The ...
Maciel, A. P., Tieghi Neto, V., Ikuta, C. R. S., Taveira, L. A. de A., Ponce, J. B., Santos, P. S. da S., & Rubira, C. M. F. (2017). Verrucous carcinoma as a clinicopathologic variant of squamous cell carcinoma. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. St. Louis. Recuperado de https://doi.org/10.1016/j.oooo.2017.05. ...
Comment:. Sections demonstrate two distinct histologic neoplasms: an inverted papilloma and a coexisting verrucous carcinoma. Microscopically, the inverted papilloma comprises less than 10% of the tumor mass. Inverted papillomas are not infrequently associated with malignant tumors, primarily squamous cell carcinoma, and in some instances malignant transformation in an inverted papilloma to carcinoma may be observed. In this case, there is no transitional zone in the sections examined to suggest that the verrucous carcinoma is arising directly from the inverted papilloma. Although immunoperoxidase stains for human papillomavirus antigens are negative in both components of the tumor mass, inverted papillomas and verrucous carcinomas have been associated with human papillomavirus infection. ...
Author: Michael Becker. In December 2015, at the age of 47, I was diagnosed with Stage IV oral squamous cell carcinoma.. More simply, I have advanced cancer of the head and neck. While initial treatment with grueling chemo-radiation appeared successful, the cancer returned one year later in both of my lungs. My prognosis shifted from potentially curable to terminal disease. The news was shocking and devastating-not just for me, but for my wife, two teenage daughters, and the rest of our family and friends.. Suddenly, my life revolved around regular appointments for chemotherapy, radiation therapy, imaging procedures, and frequent checkups. I made seemingly endless, unscheduled hospital emergency room visits-including one trip to the intensive care unit-to address some of the more severe toxicities from treatment.. All told, I suffered from more than a dozen side effects related to treatment and/or cancer progression. Some are temporary; others permanent. These include anxiety, depression, ...
Cinthia B Drachenberg MD, Remy Blanchaert MD DDS, Olga B Ioffe MD, Robert A Ord MD DDS, John C Papadimitriou MD PhD. In verrucous carcinoma (VC) the apoptotic index consistently ranged from 0.1 to 1%, Ki-67 positive nuclei were confined to the basal epithelial layer, bcl-2 was expressed only in the cytoplasm of few scattered cells and p53 mutations were present in 50% of the lesions. In squamous cell carcinoma the apoptotic index ranged from 3 to 8 %, K-67 positive nuclei were randomly distributed, bcl-2 cytoplasmic and nuclear expression was more widespread and higher than in VC. p53 positive nuclei were identified in 62.5% of the lesions. ,,,. ...
This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canadas national genomics strategy with funding from the federal government. Maintenance, support, and commercial licensing is provided by OMx Personal Health Analytics, Inc. Designed by Educe Design & Innovation Inc. ...
This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canadas national genomics strategy with funding from the federal government. Maintenance, support, and commercial licensing is provided by OMx Personal Health Analytics, Inc. Designed by Educe Design & Innovation Inc. ...
PubMed journal article Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case repor were found in PRIME PubMed. Download Prime PubMed App to iPhone, iPad, or Android
Diagnostic and Therapeutic Endoscopy is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of diagnostic and therapeutic endoscopy.
Welcome to the updated version of Pathology for Urologists! This program was designed to help Urology residents and fellows familiarize themselves with the pathologic features of common urologic entities. This will serve not only as a resource tool for your review but also as a quick reference guide to urologic pathology.
This presentation summarizes the first study of hyperbaric oxygen chemo-radiation sensitization for locally advanced squamous cell carcinomas of the oropharynx. It took the form of a Stage I dose escalation trial, designed to determine safety, feasibility and tolerability when hyperbaric oxygen was added to standard care, namely intensity modulated radiation therapy and cisplatinum chemotherapy. The presentation will describe the biological plausibility and physiologic basis for pre-radiation hyperbaric hyperoxia, and the rationale for selection of this tumor type and tumor grade. The hyperbaric dosing regimen, one based upon previous human tumor oxygen response curves, is discussed, and the critical time window for radiation therapy "beam on" from exiting the chamber discussed. Evolution from earlier sensitization studies that employed concurrent hyperbaric oxygen-radiation therapy to the modern sequential approach are described, as will its inherent advantages. A staging protocol employed to ...
Rabbit polyclonal to Albumin Resective surgery if feasible systemic chemotherapy and chemo-radiation are usually proposed unfortunately with a low impact on global prognosis [3]. Case report A 74-year-old man with a history of dyslipidaemia impaired glucose tolerance and cholelithiasis came to our attention because of dyspepsia and dorsal pain lasting for two months. He underwent an upper gastrointestinal (GI) endoscopy showing a submucosal nodule in the gastric antrum and an stomach ultrasonography (US) showing multiple gallstones and a 3 cm pancreatic body Cinacalcet lesion. A chest-abdomen contrast medium Computed Tomography (CT)-scan detected a pancreatic body lesion of 26 mm axial diameter (?) with pancreatic duct dilation and perilesional lymphadenopathy with 15 mm ?. Endoscopic US (EUS) with fine-needle aspiration (FNA) showed a 37 mm ? hypoechoic and inhomogeneous lesion comprising mesenteric-portal axis without a clear infiltration (uT3uN0 AJCC 2010) [4]. Cytology was conclusive for ...
American Journal of Dermatopathology The Men Behind the Eponym, Buschke-Lowenstein Abraham Buschke @ Who Named It e-Medicine ( ... "Buschke-Löwenstein tumor": Also known as giant condyloma acuminatum; a variety of venereal wart characterized by its large, ... This condition is sometimes referred to as "Busse-Buschke disease". In 1943, Buschke died in Theresienstadt, a Nazi ... Abraham Buschke (27 September 1868 - 23 February 1943) was a Jewish German dermatologist who was a native of Nakel in the ...
Find out information about Buschke-Lowenstein tumor. see neoplasm neoplasm or tumor, tissue composed of cells that grow in an ... Normal tissue is growth-limited, i.e., cell reproduction is equal to... Explanation of Buschke-Lowenstein tumor ... Related to Buschke-Lowenstein tumor: Buschke-Löwenstein tumor tumor:. see neoplasmneoplasm. or tumor,. tissue composed of cells ... Buschke-Lowenstein tumor , Article about Buschke-Lowenstein tumor by The Free Dictionary https://encyclopedia2. ...
Buschke-Lowenstein tumor is a relatively rare sexually transmitted disease. It is a neoplasm of the anogenital region which has ... Q. D. Chu, M. P. Vezeridis, N. P. Libbey, and H. J. Wanebo, "Giant condyloma acuminatum (Buschke-Lowenstein tumor) of the ... M. Bjorck, L. Athlin, and B. A. Lundskog, "Giant consyloma acuminatum (Buschke Lowenstein tumor of the anrectum with malignant ... A Gigantic Anogenital Lesion: Buschke-Lowenstein Tumor. Rikinder Sandhu, Zaw Min, and Nitin Bhanot ...
... N. E. Wester, E. M ... Q. D. Chu, M. P. Vezeridis, N. P. Libbey, and H. J. Wanebo, "Giant condyloma acuminatum (Buschke-Lowenstein tumor) of the ... On rare occasions progression to a Buschke-Lowenstein tumour (BLT) occurs. A BLT is a very rare, slowly growing, locally ... M. W. T. Chao and P. Gibbs, "Squamous cell carcinoma arising in a giant condyloma acuminatum (Buschke-Lowenstein tumour)," ...
Lowenstein tumor is a rare sexually transmitted disease. Its location at the anal margin is also very rare. The most ... Lowenstein tumor; HPV - human papillomavirus; RT - radiotherapy.. The Buschke - Lowenstein tumor (BLT) is a rare tumor. It ... Buschke - Lowenstein anal tumor: an ambiguous entity. Ben Kridis W.*1, Werda I.1, Charfi S.2, Toumi N.1, Boudawara T.2, Mzali R ... The Buschke - Lowenstein tumor is a rare sexually transmitted disease. Its location at the anal margin is also very rare. The ...
Buschke-Lowenstein tumour. Buschke-Lowenstein tumour is most commonly found on the glans of the penis. It is sometimes referred ... Buschke-Lowenstein tumour is a slow-growing tumour that may grow as big as 15 cm. ... If you have symptoms or your doctor thinks you might have a Buschke-Lowenstein tumour, tests will be done to make a diagnosis. ... The signs and symptoms of Buschke-Lowenstein tumour include:* an abnormal growth or sore (ulcer) on the penis - it may look ...
... the giant condyloma of Buschke and Löwenstein (GCBL) is a slow-growing, locally destructive verrucous plaque that typically ... Buschke-Lowenstein tumor successful treatment by surgical excision alone: a case report. Surg Innov. 2006 Mar. 13(1):69-72. [ ... Giant Condylomata Acuminata of Buschke and Lowenstein) and Giant Condylomata Acuminata of Buschke and Lowenstein What to Read ... Giant condyloma acuminatum (Buschke-Lowenstein tumor) of the anorectal and perianal regions. Analysis of 42 cases. Dis Colon ...
... resources and questions answered by our Genetic and Rare Diseases Information Specialists for Buschke Lowenstein tumor ... Buschke Lowenstein tumor. is a tumor that most commonly occurs near the penis or anus. This tumor often looks like a large ... Buschke Lowenstein tumor Title Other Names:. Giant condyloma acuminatum involving the prepuce and glans penis; Giant condyloma ... PubMed is a searchable database of medical literature and lists journal articles that discuss Buschke Lowenstein tumor. Click ...
BUSCHKE-LOWENSTEINS TUMOUR * 1 1/501 (0.20%) KAPOSIS SARCOMA * 1 1/501 (0.20%) ...
Buschke-Lowenstein tumor. 1/2. 3. 2. Impaling injury. 1/2. 3. 7 ...
Buschke-lowenstein tumour Hampshire UK. Mon Jan 12, 2015 5:26 am. ...
Neoadjuvant chemotherapy and penile conservation in the management of Buschke - Lowenstein tumor, a case report. ...
Giant condyloma acuminatum (Buschke-Lowenstein tumor) of the anorectal and perianal regions: analysis of 42 cases. Dis Colon ... Buschke-Lowenstein tumour of glans penis. Int J Surg Case Rep. 2014. 5:p. 215-8 ... Seborrheic keratosis over genitalia masquerading as Buschke-Lowenstein tumor. Indian J Sex Transm Dis. 2015. 36:p. 77-9 ... Buschke-Löwenstein tumor with squamous cell carcinoma treated with chemo-radiation therapy and local surgical excision: report ...
Anal Canal Perianal Tumors*Verrucous carcinoma *Buschke-Lowenstein Tumor, Giant condyloma accuminata. ... Metachronous tumor (second primary colon CA) treated similarly *Hemorrhage in an unresectable tumor can be controlled w/ ... poorly differentiated or tumor w/in 1mm. of resection margin ---gt high risk of local recurence and metastatic spread) ... tumor ---gt segmental resection, if in rectum can do full thickness proximal protectomy w/ coloanal anastomosis ...
Buschke-Lowenstein tumour (BLT) is a giant condyloma acumina, which is rare entity and represents only 1% of all populace. It ... Tumeur de Buschke-lowenstein associé à un mélanome scrotal. À propos dun cas ... Tumeur de Buschke-lowenstein associé à un mélanome scrotal. À propos dun cas ... The majority of tumors (80%) were non palpable, and incidentally discovered with scrotal ultrasonography. Eight cases were ...
A Gigantic Anal Mass: Buschke-Lowenstein Tumor in a Patient with Controlled HIV Infection with Fatal Outcome.. ...
Extremely large lesions (Buschke-Lowenstein tumor) may need radical excision.. illustration. condyloma latum. A mucous patch, ... giant condyloma Buschke-Löwenstein tumor.. condyloma la´tum a broad, flat syphilitic condyloma on the folds of moist skin, ... giant condyloma Buschke-Löwenstein tumor.. condyloma la´tum a wide, flat, syphilitic condyloma occurring on moist skin, ...
Extremely large lesions (Buschke-Lowenstein tumor) may need radical excision.. See: Cardiac Cycle illustration. cell cycle. The ...
Perianal giant condyloma acuminatum (Buschke-Lowenstein tumor): report of 3 cases. Leone V., Misuri D., Giovane A., Console N ... Adenomatoid odontogenic tumor associated to dentigerous cyst. Morelli Heiderich De Mattos A., Sampaio Queiroz C., Suruagy Motta ...
Rapid progression of an anal Buschke-Lowenstein tumour into a metastasising squamous cell carcinoma in an HIV-infected patient ...
... so-called giant condyloma of Buschke and Lowenstein) should be classified as verrucous carcinoma; this tumor shows aggressive ... and tumor grade (p=0.024). MTV defined as a function of maximum SUV and tumor grade improved the prediction of pathologic tumor ... the importance of tumor versus host Gal-1 in tumor progression is undefined. Here we offer evidence that implicates tumor Gal-1 ... Tumor Galectin-1 Mediates Tumor Growth and Metastasis through Regulation of T-Cell Apoptosis CANCER RESEARCH Banh, A., Zhang, J ...
Glansectomy: an alternative surgical treatment for Buschke-Lowenstein tumors of the penis. Urology 2001;57:966-969. ... Glansectomy: an alternative surgical treatment for Buschke-Lowenstein tumors of the penis. . Urology. 2001. ;. 57. :. 966. - ... Tumors of the penis. In: Wein AJ, Kavoussi L, Novick AC, eds. Campbell-Walsh Urology. 9th ed. Philadelphia: Saunders; 2007:959- ... G2 a moderately differentiated tumor (. 50% anaplastic cells); and G4 an undifferentiated tumor.13 Additional tumor ...
... including Ackerman tumor (solitary oral mucosal lesion), Buschke-Lowenstein tumor (genital involvement), florid oral ... Regression of deeply infiltrating giant condyloma (Buschke-Lowenstein tumor) following long-term intralesional interferon alpha ... Although the tumors are slow growing with little risk for metastasis, they may be locally invasive with deep involvement of the ... When surgery is not ideal due to the tumor size or location or the patients preference, other treatment modalities with ...
from typical squamous tumors. One is verrucous carcinoma (also known as giant condyloma or Buschke-Lowenstein tumor), which ... Tumors below the dentate line are considered anal margin carcinomas. Few anal margin tumors extend into the anal canal. ... Differentiation (well-differentiated tumors are more favorable than poorly differentiated tumors).. *Lymph Node Involvement: ... are tumors with aggressive biologic behavior and an unfavorable prognosis compared to typical SCC. Tumors of the more distal ...
Because of the tumors large extent in this case, curative therapy would have been achieved by wide surgical excision. METHOD ... Scrotal Buschke-Lowenstein tumor in an AIDS patient.. *Omar Pacha, Melanie M Pickett, Adelaide A Hebert ... Intra-Abdominal Localisation of a Buschke-Lowenstein Tumour: Case Presentation and Review of the Literature. *Niklas Wester, E ... Tumor de Buschke-Löwenstein en una paciente pediátrica. *Gabriela Ambriz-González, Laura Cecilia Escobar-Zavala, Carrillo de la ...
The giant condyloma or Buschke-Lowenstein tumor is a slow-growing, cauliflower-like tumor that is locally aggressive and ...
  • It was hard in consistency and gave the look of a bulky tumor. (hindawi.com)
  • Clinically, the tumor appears as a rather bulky mass, budding, of cauliflower aspect, which evolves in surface and in depth. (exp-oncology.com.ua)
  • Bulky tumors have been shrunk with preoperative chemoradiation, followed by radical surgery, in some instances followed by reconstructive surgery. (medscape.com)
  • Se presentó un paciente masculino de 68 años, que acudió a consulta de Dermatología por presentar lesiones vegetantes en coliflor en región inguinal izquierda, pubis y perineales, de 10 años de evolución y nunca tratadas. (bvsalud.org)
  • however, an inguinal tumor was diagnosed intraoperatively and was resected as much as possible. (bvsalud.org)
  • Sacral resection en bloc and anus praeter were performed following radiotherapy treatment. (eurorad.org)
  • The pathology report should include tumor diameter, tumor thickness, and whether the following tissues are infiltrated: Lamina propria, corpus spongiosum, urethra, and preputium, and whether resection borders are free of tumor. (oncolex.org)
  • Although the tumor resection was macroscopically incomplete, he was followed up without any treatment because the tumor was histologically diagnosed as lipoma. (bvsalud.org)
  • we will try to identify the epidemiological, clinical, therapeutic and evolutionary aspects of this tumor. (exp-oncology.com.ua)
  • At the deep aspect of the biopsy specimen, tumor cells intercalated between collagen bundles in linear strands. (mdedge.com)
  • Histopathological evaluation (with the use of ancillary studies, including immunohistochemical stains for neuroendocrine markers, if necessary) of the removed tumor or biopsy material confirms the diagnosis. (clinicaladvisor.com)
  • In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. (ac.ke)
  • With the history of colon cancer, radiation treatment, and chemotherapy, the possible malignancy diagnoses included primary skin cancers, viral tumors, and cutaneous metastasis. (mdedge.com)
  • Tumor cells can be carried throughout the body in the bloodstream or in the lymph and can settle in various organs and tissues, forming metastases. (thefreedictionary.com)
  • The spermatic cord tumor was histologically diagnosed as well differentiated liposarcoma. (bvsalud.org)
  • Although the tumors are slow growing with little risk for metastasis, they may be locally invasive with deep involvement of the surrounding structures. (mdedge.com)
  • Presentamos el caso de un hombre de 21 años de edad, infectado por el virus de la inmunodeficiencia humana (VIH) que presenta lesiones verrucosas gigantes compatibles con un tumor de Buschke-Lowenstein (TBL) que afectaban la región perineal, anorrectal y genitales externos. (bvsalud.org)
  • The postulated viral origin of these tumors has led to the use of IFN with moderate success. (medscape.com)
  • This often-aggressive tumor phenotype has been characterized by its poor prognosis, mostly attributable to its late presentation and heterogeneity of surgical care because of the paucity of cases treated at most centers. (jnccn.org)
  • CGA concentration correlates with tumor volume, and it may be useful for staging, prognosis, and monitoring response to therapy. (clinicaladvisor.com)
  • Interferon treatment was started which initially led to tumour reduction but was complicated by an interferon-induced pancreatitis, pneumonia, and fasciitis necroticans resulting in death. (hindawi.com)
  • Imiquimod was effective in combination with carbon dioxide laser ablation in a patient unable to tolerate surgery, whose tumor was positive for HPV-6. (medscape.com)
  • In 1894 with pathologist Otto Busse (1867-1922), Buschke described an infectious disease caused by the fungus Cryptococcus neoformans. (wikipedia.org)
  • Histopathology report was suggestive of syringocystadenoma papilliformis which is an apocrine sweat gland tumor and she was referred back to us. (jpgo.org)
  • The severity and extent of the tumour both determine the treatment and patient outcome. (hindawi.com)
  • We present a literature overview on the treatment options for a Buschke-Lowenstein tumour, with emphasis on interferon therapy, with all the advantages and disadvantages. (hindawi.com)
  • Treatment of these tumors begins with removal by surgery. (cdc.gov)
  • The autonomous growth of tumors was demonstrated by transplantation experiments in which tumors from one animal survived and grew for many years on secondary animal hosts. (thefreedictionary.com)
  • Chemotherapy and radiation therapy have also been shown to be effective treatments for this tumor type. (cdc.gov)
  • While some studies show evidence of new aggressive behavior after radiation therapy, more than a few case reports document resolution of small tumors after radiation. (medscape.com)
  • One regimen that lead to a complete response consists of mitomycin C and 5-fluorouracil administered concomitantly with radiation therapy 50.4 Gy to the tumor bed and prophylactic irradiation of the regional nodes. (medscape.com)
  • 1 These tumors have a slow and localized growth pattern but can be locally aggressive. (mdedge.com)