Burkholderia cepacia complex
Burkholderia cepacia
Burkholderia
A genus of gram-negative, aerobic, rod-shaped bacteria. Organisms in this genus had originally been classified as members of the PSEUDOMONAS genus but overwhelming biochemical and chemical findings indicated the need to separate them from other Pseudomonas species, and hence, this new genus was created.
Cystic Fibrosis
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Burkholderia cenocepacia
Burkholderia pseudomallei
Rec A Recombinases
A family of recombinases initially identified in BACTERIA. They catalyze the ATP-driven exchange of DNA strands in GENETIC RECOMBINATION. The product of the reaction consists of a duplex and a displaced single-stranded loop, which has the shape of the letter D and is therefore called a D-loop structure.
Bacterial Typing Techniques
Hydrogen Cyanide
Sputum
Environmental Microbiology
Biofilms
Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.
Polymorphism, Restriction Fragment Length
Pyrrolnitrin
Benzethonium
Bactericidal cationic quaternary ammonium surfactant used as a topical anti-infective agent. It is an ingredient in medicaments, deodorants, mouthwashes, etc., and is used to disinfect apparatus, etc., in the food processing and pharmaceutical industries, in surgery, and also as a preservative. The compound is toxic orally as a result of neuromuscular blockade.
Melioidosis
Opportunistic Infections
Sequence Analysis, DNA
Sodium Benzoate
RNA, Ribosomal, 16S
Polymerase Chain Reaction
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Tobramycin
Random Amplified Polymorphic DNA Technique
Technique that utilizes low-stringency polymerase chain reaction (PCR) amplification with single primers of arbitrary sequence to generate strain-specific arrays of anonymous DNA fragments. RAPD technique may be used to determine taxonomic identity, assess kinship relationships, analyze mixed genome samples, and create specific probes.
4-Butyrolactone
Virulence
Electrophoresis, Gel, Pulsed-Field
Gel electrophoresis in which the direction of the electric field is changed periodically. This technique is similar to other electrophoretic methods normally used to separate double-stranded DNA molecules ranging in size up to tens of thousands of base-pairs. However, by alternating the electric field direction one is able to separate DNA molecules up to several million base-pairs in length.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Soil Microbiology
Quorum Sensing
DNA, Ribosomal
Gram-Negative Bacterial Infections
Species Specificity
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Microbial Viability
Burkholderia gladioli
DNA Fingerprinting
A technique for identifying individuals of a species that is based on the uniqueness of their DNA sequence. Uniqueness is determined by identifying which combination of allelic variations occur in the individual at a statistically relevant number of different loci. In forensic studies, RESTRICTION FRAGMENT LENGTH POLYMORPHISM of multiple, highly polymorphic VNTR LOCI or MICROSATELLITE REPEAT loci are analyzed. The number of loci used for the profile depends on the ALLELE FREQUENCY in the population.
Microbial Sensitivity Tests
2,4,5-Trichlorophenoxyacetic Acid
Culture Media
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Glanders
Drug Resistance, Bacterial
Gene Expression Regulation, Bacterial
Virulence Factors
Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)
Base Sequence
Pseudomonas
Biodegradation, Environmental
Pseudomonas aeruginosa
Salicylate induces an antibiotic efflux pump in Burkholderia cepacia complex genomovar III (B. cenocepacia). (1/151)
An antibiotic efflux gene cluster that confers resistance to chloramphenicol, trimethoprim, and ciprofloxacin has been identified in Burkholderia cenocepacia (genomovar III), an important cystic fibrosis pathogen. Five open reading frames have been identified in the cluster. There is apparently a single transcriptional unit, with llpE encoding a lipase-like protein, ceoA encoding a putative periplasmic linker protein, ceoB encoding a putative cytoplasmic membrane protein, and opcM encoding a previously described outer membrane protein. A putative LysR-type transcriptional regulatory gene, ceoR, is divergently transcribed upstream of the structural gene cluster. Experiments using radiolabeled chloramphenicol and salicylate demonstrated active efflux of both compounds in the presence of the gene cluster. Salicylate is an important siderophore produced by B. cepacia complex isolates, and both extrinsic salicylate and iron starvation appear to upregulate ceoR promoter activity, as does chloramphenicol. These results suggest that salicylate is a natural substrate for the efflux pump in B. cenocepacia and imply that the environment of low iron concentration in the cystic fibrosis lung can induce efflux-mediated resistance, even in the absence of antibiotic selective pressure. (+info)The Burkholderia cepacia epidemic strain marker is part of a novel genomic island encoding both virulence and metabolism-associated genes in Burkholderia cenocepacia. (2/151)
The Burkholderia cepacia epidemic strain marker (BCESM) is a useful epidemiological marker for virulent B. cenocepacia strains that infect patients with cystic fibrosis. However, there was no evidence that the original marker, identified by random amplified polymorphic DNA fingerprinting, contributed to pathogenicity. Here we demonstrate that the BCESM is part of a novel genomic island encoding genes linked to both virulence and metabolism. The BCESM was present on a 31.7-kb low-GC-content island that encoded 35 predicted coding sequences (CDSs): an N-acyl homoserine lactone (AHL) synthase gene (cciI) and corresponding transcriptional regulator (cciR), representing the first time cell signaling genes have been found on a genomic island; fatty acid biosynthesis genes; an IS66 family transposase; transcriptional regulator CDSs; amino acid metabolism genes; and a group of hypothetical genes. Mutagenesis of the AHL synthase, amidase (amiI), and porin (opcI) genes on the island was carried out. Testing of the isogenic mutants in a rat model of chronic lung infection demonstrated that the amidase played a role in persistence, while the AHL synthase and porin were both involved in virulence. The island, designated the B. cenocepacia island (cci), is the first genomic island to be defined in the B. cepacia complex and its discovery validates the original epidemiological correlation of the BCESM with virulent CF strains. The features of the cci, which overlap both pathogenicity and metabolism, expand the concept of bacterial pathogenicity islands and illustrate the diversity of accessory functions that can be acquired by lateral gene transfer in bacteria. (+info)Importance of the ornibactin and pyochelin siderophore transport systems in Burkholderia cenocepacia lung infections. (3/151)
Previously, orbA, the gene encoding the outer membrane receptor for ferric-ornibactin, was identified in Burkholderia cenocepacia K56-2, a strain which produces ornibactin, salicylic acid, and negligible amounts of pyochelin. A K56-2 orbA mutant was less virulent than the parent strain in a rat agar bead infection model. In this study, an orbA mutant of B. cenocepacia Pc715j which produces pyochelin in addition to ornibactin and salicylic acid was constructed. The gene encoding the outer membrane receptor for ferric-pyochelin (fptA) was also identified. An fptA mutant was constructed in Pc715j and shown to be deficient in [(59)Fe]pyochelin uptake. A 75-kDa iron-regulated protein was identified in outer membrane preparations of Pc715j that was absent in outer membrane preparations of Pc715jfptA::tp. Pc715jfptA::tp and Pc715jorbA::tp produced smaller amounts of their corresponding siderophores. Both Pc715jorbA::tp and Pc715jfptA::tp were able to grow in iron starvation conditions in vitro. In the agar bead model, the Pc715jorbA::tp mutant was cleared from the lung, indicating that the pyochelin uptake system does not compensate for the absence of a functional ornibactin system. Pc715jfptA::tp persisted in rat lung infections in numbers similar to those of the parent strain, indicating that the ferric-ornibactin uptake system could compensate for the defect in ferric-pyochelin uptake in vivo. These studies suggest that the ornibactin uptake system is the most important siderophore-mediated iron transport system in B. cenocepacia lung infections. (+info)Genetic characterization of a multicomponent signal transduction system controlling the expression of cable pili in Burkholderia cenocepacia. (4/151)
Cable pili are peritrichous organelles expressed by certain strains of Burkholderia cenocepacia, believed to facilitate colonization of the lower respiratory tract in cystic fibrosis patients. The B. cenocepacia cblBACDS operon encodes the structural and accessory proteins required for the assembly of cable pili, as well as a gene designated cblS, predicted to encode a hybrid sensor kinase protein of bacterial two-component signal transduction systems. In this study we report the identification of two additional genes, designated cblT and cblR, predicted to encode a second hybrid sensor kinase and a response regulator, respectively. Analyses of the deduced amino acid sequences of the cblS and cblT gene products revealed that both putative sensor kinases have transmitter and receiver domains and that the cblT gene product has an additional C-terminal HPt domain. Mutagenesis of the cblS, cblT, or cblR gene led to a block in expression of CblA, the major pilin subunit, and a severe decrease in cblA transcript abundance. Using transcriptional fusion analyses, the decrease in the abundance of the cblA transcript in the cblS, cblT, and cblR mutants was shown to be due to a block in transcription from the cblB-proximal promoter, located upstream of the cblBACDS operon. Furthermore, ectopic expression of either cblS or cblR in wild-type B. cenocepacia strain BC7 led to a significant increase, while ectopic expression of cblT resulted in a dramatic decrease, in abundance of the CblA major pilin and the cblA transcript. Our results demonstrate that the B. cenocepacia cblS, cblT, and cblR genes are essential for cable pilus expression and that their effect is exerted at the level of transcription of the cblBACDS operon. These findings are consistent with the proposed function of the cblSTR gene products as a multicomponent signal transduction pathway controlling the expression of cable pilus biosynthetic genes in B. cenocepacia. (+info)Identification of Burkholderia cenocepacia genes required for bacterial survival in vivo. (5/151)
Burkholderia cenocepacia (formerly Burkholderia cepacia complex genomovar III) causes chronic lung infections in patients with cystic fibrosis. In this work, we used a modified signature-tagged mutagenesis (STM) strategy for the isolation of B. cenocepacia mutants that cannot survive in vivo. Thirty-seven specialized plasposons, each carrying a unique oligonucleotide tag signature, were constructed and used to examine the survival of 2,627 B. cenocepacia transposon mutants, arranged in pools of 37 unique mutants, after a 10-day lung infection in rats by using the agar bead model. The recovered mutants were screened by real-time PCR, resulting in the identification of 260 mutants which presumably did not survive within the lungs. These mutants were repooled into smaller pools, and the infections were repeated. After a second screen, we isolated 102 mutants unable to survive in the rat model. The location of the transposon in each of these mutants was mapped within the B. cenocepacia chromosomes. We identified mutations in genes involved in cellular metabolism, global regulation, DNA replication and repair, and those encoding bacterial surface structures, including transmembrane proteins and cell surface polysaccharides. Also, we found 18 genes of unknown function, which are conserved in other bacteria. A subset of 12 representative mutants that were individually examined using the rat model in competition with the wild-type strain displayed reduced survival, confirming the predictive value of our STM screen. This study provides a blueprint to investigate at the molecular level the basis for survival and persistence of B. cenocepacia within the airways. (+info)Production of exopolysaccharide by Burkholderia cenocepacia results in altered cell-surface interactions and altered bacterial clearance in mice. (6/151)
Despite the characterization of some Burkholderia cepacia complex exopolysaccharides (EPSs), little is known about the role of EPSs in the pathogenicity of B. cepacia complex organisms. We describe 2 Burkholderia cenocepacia (genomovar III) isolates obtained from a patient with cystic fibrosis (CF): the nonmucoid isolate C8963 and the mucoid isolate C9343. Both isolates had identical random amplified polymorphic DNA patterns. C9343 produced a capsule composed of the EPSs PS-I and PS-II, as well as alpha -1,6-glucan. These isolates exhibited several phenotypic differences: C8963 synthesized octanoyl-homoserine lactone and produced biofilms, but C9343 did not; in a mouse model of pulmonary infection, C8963 was cleared more rapidly than was C9343; and C9343 interacted poorly with macrophages and neutrophils, compared with C8963, suggesting that the C9343 capsule interfered with cell-surface interactions. Overproduction of EPS by C9343 resulted in a mucoid appearance and interfered with cell-surface interactions and clearance in an animal model. This mucoid colonial appearance could enhance the persistence and virulence of this important CF-related pathogen. (+info)Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia. (7/151)
Burkholderia cenocepacia strain K56-2, a representative of the Burkholderia cepacia complex, is part of the epidemic and clinically problematic ET12 lineage. The strain produced plant tissue watersoaking (ptw) on onion tissue, which is a plant disease-associated trait. Using plasposon mutagenesis, mutants in the ptw phenotype were generated. The translated sequence of a disrupted gene (ptwD4) from a ptw-negative mutant showed homology to VirD4-like proteins. Analysis of the region proximal to the transfer gene homolog identified a gene cluster located on the 92-kb resident plasmid that showed homology to type IV secretion systems. The role of ptwD4, ptwC, ptwB4, and ptwB10 in the expression of ptw activity was determined by conducting site-directed mutagenesis. The ptw phenotype was not expressed by K56-2 derivatives with a disruption in ptwD4, ptwB4, or ptwB10 but was observed in a derivative with a disruption in ptwC. Complementation of ptw-negative K56-2 derivatives in trans resulted in complete restoration of the ptw phenotype. In addition, analysis of culture supernatants revealed that the putative ptw effector(s) was a secreted, heat-stable protein(s) that caused plasmolysis of plant protoplasts. A second chromosomally encoded type IV secretion system with complete homology to the VirB-VirD system was identified in K56-2. Site-directed mutagenesis of key secretory genes in the VirB-VirD system did not affect expression of the ptw phenotype. Our findings indicate that in strain K56-2, the plasmid-encoded Ptw type IV secretion system is responsible for the secretion of a plant cytotoxic protein(s). (+info)Burkholderia cepacia genomovar III and Burkholderia vietnamiensis double infection in a cystic fibrosis child. (8/151)
Herein we report a case of a cystic fibrosis child who was simultaneously infected with Burkholderia cepacia genomovar III and Burkholderia vietnamiensis. After antimicrobial therapy only B. cepacia genomovar III persisted. (+info)
Social interactions in the Burkholderia cepacia complex: biofilms and quorum sensing. - Semantic Scholar
Distribution and genomic location of active insertion sequences in the Burkholderia cepacia complex | Microbiology Society
A General Protein O-glycosylation System Within the Burkholderia Cepacia Complex Is Involved in Motility and Virulence - PubMed
Azithromycin in Patients With CF, Infected With Burkholderia Cepacia Complex - Full Text View - ClinicalTrials.gov
Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis | European Cystic Fibrosis Society (ECFS)
ফার্মাসিউটিক্যালে নতুন উদ্বেগের নাম Burkholderia cepacia complex (Bcc) - PharmaBangla
Burkholderia cepacia complex | Johns Hopkins ABX Guide
burkholderia cepacia complex Archives - PacBio
Targeting the bacterial cytoskeleton of CF pathogens for antimicrobial development - A cautionary tale? - ePrints - Newcastle...
U.S. FDA Investigates B. cepacian Complex Outbreak Linked to Personal Care
Marine Drugs | Free Full-Text | Antimicrobial Activity of Monoramnholipids Produced by Bacterial Strains Isolated from the Ross...
Synthesis of 4-Amino-4-Deoxy-L-Arabinose C-Phosphonate Esters as Transferase Inhibitors | EUROCARB 2019
CAZy - Bacteria
ecorn-cf: Question single
KEGG T00771: BCAL0647
KEGG SSDB Paralog Search Result: bur:Bcep18194 A5156
Updated Version of the Burkholderia cepacia Complex Experimental Strain Panel | Journal of Clinical Microbiology
Taxonomy and Identification of the Burkholderia cepacia Complex | Journal of Clinical Microbiology
A Decade of Burkholderia cenocepacia Virulence Determinant Research<...
Which antibiotics are best to treat worsening symptoms in people with cystic fibrosis with persistent Burkholderia cepacia...
EMBL: CP000871
Phase variation has a role in Burkholderia ambifaria niche adaptation - Espace INRS
Treatments to cure long-term infections with Burkholderia cepacia in people with cystic fibrosis | Cochrane
Items where Author is Nicholson, Audrey - Northumbria Research Link
Burkholderia cenocepacia ATCC ® BAA-245D-5™
https://www.thefreelibrary.com/Environmental+Burkholderia+cepacia+complex+isolates+in+human...-a0161011310
Genome-wide transcription start site profiling in biofilm-grown Burkholderia cenocepacia J2315
KEGG PATHWAY: Glycolysis / Gluconeogenesis - Burkholderia cenocepacia J2315
Recombinant Burkholderia vietnamiensis UPF0060 membrane protein Bcep1808 1236 (Bcep1808 1236) - Cusabio
bcscV - Type III secretion system protein - Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 ...
ureA - Urease subunit gamma - Burkholderia cenocepacia (strain HI2424) - ureA gene & protein
Pre GI: Gene
Profile | Biosciences | University of Exeter
Reclassification of the Specialized Metabolite Producer Pseudomonas mesoacidophila ATCC 31433 as a Member of the Burkholderia...
Pre GI: Gene
Predicted Orthologs - RBBH
Priebe Laboratory | Boston Childrens Hospital
A0K968 | SWISS-MODEL Repository
A0K923 | SWISS-MODEL Repository
orange complex bacteria (OCB) - Allie: Abbreviation / Long Form Info.
Successful containment of a nosocomial outbreak of Burkholderia cepacia in a special care baby unit of a base hospital in Sri...
Burkholderia ambifaria Putative membrane protein|gentaur.com
Grasses of the BCEP - Butte Creek Ecological Preserve - CSU, Chico
Bank of Southern California NA Appoints John E. Chung as Group Managing Director - Send2Press Newswire
BCC05U5 (BCC M425-0000-1A-005-EX43T2-020) Single-Ended Cordsets - BALLUFF
BCC05U7 (BCC M425-0000-1A-005-EX43T2-100) Single-Ended Cordsets - BALLUFF
Scientific Articles - The International Burkholderia cepacia Working Group
Inhibition of co-colonizing cystic fibrosis-associated pathogens by Pseudomonas aeruginosa and Burkholderia multivorans. -...
Burkholderia cepacia complex - Infectious Disease and Antimicrobial Agents
Development of Galleria mellonella as an Alternative Infection Model for the Burkholderia cepacia Complex | Infection and...
Pharmaceutical Microbiology Resources: Burkholderia cepacia - Risks in Context for Non-Sterile Pharmaceutical Products (Webinar)
DM42 5897 protein (Burkholderia cepacia) - STRING interaction network
WL94 09065 protein (Burkholderia cepacia) - STRING interaction network
Down the sink: the local experience of a Burkholderia cenocepacia outbreak at the Canberra Hospital - 2021 ACIPC Conference
Hong Kong investigates invasive Burkholderia cepacia cluster - Outbreak News Today
Burkholderia cepacia (Palleroni and Holmes) Yabuuchi et al. ATCC ®
The intracellular behaviour of Burkholderia cenocepacia in murine macrophages by Jennifer S. Tolman
The unexpected discovery of a novel low-oxygen-activated locus for the anoxic persistence of Burkholderia cenocepacia -ORCA
Outcomes of lung transplantation for cystic fibrosis in a large UK cohort - Northumbria Research Link
British Library EThOS: Antimicrobial strategies against Burkholderia cepacia
Nurse Assist recalls I.V. Flush Syringes: Possibly linked to Burkholderia cepacia outbreak - Outbreak News Today
In Situ Hybridization of Burkholderia Cepacia Cells
Complex bacterium writes new evolutionary story | EurekAlert! Science News
CiNii Articles - A cross-sectional study on the periodontal status and prevalence of red complex periodontal...
Burkholderia cepacia NCTC 10661 | TM Media - Titan Biotech Ltd.
Lyme Disease Therapies
10 brands of baby wipes recalled due to pneumonia-causing bacteria contamination | Reclaim Our Republic
Survival curves for D. melanogaster infected with B. ce | Open-i
Bank of Southern California, N.A. Appoints Ann Torrico as Managing Director - Send2Press Newswire
perf-regression/margo-p2p-latency-avg-only.patch · 477c28bcc75f5800c32414b659ec142757c12e04 · sds / sds-tests · GitLab
Burkholderia cepacia complex
... in the NCBI Taxonomy Browser Type strain of Burkholderia cepacia complex at BacDive, the Bacterial ... Burkholderia cepacia complex (BCC), or simply Burkholderia cepacia, is a group of catalase-producing, lactose-nonfermenting, ... Burkholderia cepacia is also found in marine environment (marine sponge) and some strain of Burkholderia cepacia can tolerate ... "Stenotrophomonas maltophilia and Burkholderia cepacia Complex". Mandell, Douglas, and Bennett's principles and practice of ...
Ornibactin
Coenye T, Vandamme P, Govan JR, LiPuma JJ (October 2001). "Taxonomy and identification of the Burkholderia cepacia complex". ... Speert DP (September 2002). "Advances in Burkholderia cepacia complex". Paediatric Respiratory Reviews. 3 (3): 230-5. doi: ... "Ornibactin production and transport properties in strains of Burkholderia vietnamiensis and Burkholderia cepacia (formerly ... LiPuma JJ (September 1998). "Burkholderia cepacia. Management issues and new insights". Clinics in Chest Medicine. 19 (3): 473- ...
Burkholderia cenocepacia
... is one of over twenty bacteria in the Burkholderia cepacia complex (Bcc), and among these species, it ... Within the Burkholderia genus, the Burkholderia cepacia complex contains over 20 related species that cause opportunistic ... is Burkholderia cenocepacia, a member of a bacterial group collectively referred to as the Burkholderia cepacia complex." ... It is one of over 20 species in the Burkholderia cepacia complex (Bcc) and is notable due to its virulence factors and inherent ...
Burkholderia metallica
and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia complex". Int. J. Syst. Evol. Microbiol. 58 ... "Burkholderia metallica". Peter Vandamme. "Identification of Burkholderia cepacia complex bacteria" (PDF). Archived from the ... "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. nov., Burkholderia seminalis sp. nov. ... a bacterium from the genus of Burkholderia and the family of Burkholderiaceae which belongs to the Burkholderia cepacia complex ...
Burkholderia contaminans
... bacterium from the genus of Burkholderia and the family of Burkholderiaceae and belongs to the Burkholderia cepacia complex, ... Rose, H.; Baldwin, A.; Dowson, C. G.; Mahenthiralingam, E. (2009). "Biocide susceptibility of the Burkholderia cepacia complex ... Burkholderia acidipaludis can cause biliary sepsis. "Genus Burkholderia". List of Prokaryotic Names with Standing in ... Type strain of Burkholderia contaminans at BacDive - the Bacterial Diversity Metadatabase v t e (Articles with short ...
Povidone-iodine
Rose H, Baldwin A, Dowson CG, Mahenthiralingam E (March 2009). "Biocide susceptibility of the Burkholderia cepacia complex". ... The non-sterile form of Povidone iodine has a long history of intrinsic contamination with Burkholderia cepacia (aka ... These deficiencies were overcome by the discovery and use of PVP-I, in which the iodine is carried in a complexed form and the ... They carried out tests in vitro to demonstrate anti-bacterial activity, and found that the complex was less toxic in mice than ...
Burkholderia arboris
and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia complex". International Journal of ... B. arboris belongs to the Burkholderia cepacia complex. "J.P. Euzéby: List of bacterial names with standing in nomenclature". " ... "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. nov., Burkholderia seminalis sp. nov. ... Burkholderia arboris is a Gram-negative, aerobic, non-spore-forming bacterium of the genus Burkholderia and the family ...
Burkholderia territorii
"Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from ... "Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from ... Burkholderia territorii belongs to the Burkholderia cepacia complex. LSPN lpsn.dsmz.de UniProt De Smet, B; Mayo, M; Peeters, C ... Burkholderia territorii is a bacterium from the genus of Burkholderia. ...
Burkholderia pseudomultivorans
... belongs to the Burkholderia cepacia complex. LSPN lpsn.dsmz.de Straininfo of Burkholderia ... Burkholderia pseudomultivorans is a bacterium from the genus Burkholderia and the family Burkholderiaceae which was isolated ... UniProt Type strain of Burkholderia pseudomultivorans at BacDive - the Bacterial Diversity Metadatabase v t e (Articles with ... pseudomultivorans Srinivasan, S; Kim, J; Kang, S. R.; Jheong, W. H.; Lee, S. S. (2013). "Burkholderia humi sp. nov., isolated ...
Burkholderia seminalis
and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia complex". International Journal of ... bacterium from the genus Burkholderia and the family Burkholderiaceae which belongs to the Burkholderia cepacia complex. " ... "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. nov., Burkholderia seminalis sp. nov. ... "Burkholderia seminalis DSM 23518". UniProt. Retrieved 2 October 2015. Type strain of Burkholderia seminalis at BacDive - the ...
Burkholderia latens
and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia complex". Int. J. Syst. Evol. Microbiol. 58 ... and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia complex". ijsb.sgmjournals.org. Archived ... "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. nov., Burkholderia seminalis sp. nov. ... "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. nov., Burkholderia seminalis sp. nov. ...
Burkholderia diffusa
and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia complex". Int. J. Syst. Evol. Microbiol. 58 ... "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. nov., Burkholderia seminalis sp. nov. ... bacterium from the genus of Burkholderia and the family of Burkholderiaceae which belongs to the Burkholderia cepacia complex ... "hisA - ProFAR isomerase - Burkholderia diffusa - hisA gene & protein". Type strain of Burkholderia diffusa at BacDive - the ...
Burkholderia stagnalis
"Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from ... "Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from ... Burkholderia stagnalis belongs to the Burkholderia cepacia complex. LSPN lpsn.dsmz.de UniProt De Smet, B; Mayo, M; Peeters, C; ... Burkholderia stagnalis is a bacterium from the genus of Burkholderia. ...
Burkholderia dolosa
... is a species of bacteria. It is a member of the Burkholderia cepacia complex. This particular strain is ... cite web}}: Missing or empty ,title= (help) "Burkholderia dolosa". NCBI Taxonomy Browser. 152500. Type strain of Burkholderia ...
Abdominal obesity
LiPuma JJ, Spilker T, Coenye T, Gonzalez CF (June 2002). "An epidemic Burkholderia cepacia complex strain identified in soil". ...
Claire Wainwright
"Factors Influencing Acquisition of Burkholderia Cepacia Complex Organisms in Patients with Cystric Fibrosis". Journal of ...
Cystic fibrosis
Lord R, Jones AM, Horsley A (April 2020). "Antibiotic treatment for Burkholderia cepacia complex in people with cystic fibrosis ... opportunistic infection due to Burkholderia cepacia complex can occur, especially through transmission from patient to patient ... the effectiveness of antibiotics for pulmonary exacerbations in people with cystic fibrosis and Burkholderia cepacia complex or ... Eventually, Pseudomonas aeruginosa (and sometimes Burkholderia cepacia) dominates. By 18 years of age, 80% of patients with ...
Osteomyelitis
The Burkholderia cepacia complex has been implicated in vertebral osteomyelitis in intravenous drug users. In general, ... Weinstein, Lenny; Knowlton, Christin A.; Smith, Miriam A. (2007-12-16). "Cervical osteomyelitis caused by Burkholderia cepacia ... The diagnosis of osteomyelitis is complex and relies on a combination of clinical suspicion and indirect laboratory markers ...
O-linked glycosylation
"A general protein O-glycosylation system within the Burkholderia cepacia complex is involved in motility and virulence". ... Ribitol, xylose and glucuronic acid can be added to this structure in a complex modification that forms a long sugar chain. ... O-GlcNAcylation and phosphorylation can occur on the same threonine and serine residues, suggesting a complex relationship ... Glucosphingolipids, however, are often modified and can become a lot more complex. Biosynthesis of galacto- and ...
Fusarium solani
One particular method is the use of the bacterial complex Burkholderia cepacia, which is a registered control method. This ... However, a given species within the complex may not be as widespread and may not have the same ecology as others in the complex ... The current concept of F. solani is as a species complex consisting of multiple, closely related and morphologically poorly ... There is a proposed concept for the entire genus - widely subscribed by specialists - that would include this complex. However ...
Burkholderia lata
... a complex within the Burkholderia cepacia complex, comprises at least two novel species, Burkholderia contaminans sp. nov. and ... a bacterium from the genus of Burkholderia and the family of Burkholderiaceae which belongs to the Burkholderia cepacia complex ... "Burkholderia lata Taxon Passport". StrainInfo. Retrieved 2013-06-12. "Burkholderia lata". Uniprot.org. Retrieved 2013-06-12. ... Type strain of Burkholderia lata at BacDive - the Bacterial Diversity Metadatabase v t e (Articles with short description, ...
Burkholderia anthina
"Burkholderia anthina sp. nov. and Burkholderia pyrrocinia, two additional Burkholderia cepacia complex bacteria, may confound ... Burkholderia J.P. Euzéby: List of Prokaryotic names with Standing in Nomenclature "Burkholderia anthina". NCBI Taxonomy Browser ... Type strain of Burkholderia anthina at BacDive - the Bacterial Diversity Metadatabase v t e (Articles with short description, ... Burkholderia anthina is a species of bacteria of the family Burkholderiaceae. Vandamme, Peter; Henry, Deborah; Coenye, Tom; ...
Burkholderia pyrrocinia
"Burkholderia anthina sp. nov. and Burkholderia pyrrocinia, two additional Burkholderia cepacia complex bacteria, may confound ... "Polyphasic Characterisation of Burkholderia cepacia-Like Isolates Leading to the Emended Description of Burkholderia pyrrocinia ... "Burkholderia pyrrocinia". NCBI Taxonomy Browser. 60550. "Genus Burkholderia". List of Prokaryotic Names with Standing in ... Burkholderia pyrrocinia is a Gram-negative bacterium which has been found in soil as well as in the sputum of patients with ...
Burkholderia gladioli
... is closely related to, and often mistaken for, a member of the Burkholderia cepacia complex. This ... PubMed article on PCR identification of Burkholderia EMedicine overview of Burkholderia Type strain of Burkholderia gladioli at ... Burkholderia gladioli can be distinguished from the other Burkholderia because it is oxidase negative B. gladioli is indole ... NCBI: Burkholderia gladioli pv. cocovenerans (no rank) "Genus burkholderia". LPSN - List of Prokaryotic names with Standing in ...
Walter H. Burkholder
Bacterial strains from the Burkholderia cepacia complex (Bcc) are opportunistic pathogens in humans with cystic fibrosis and ... Burkholderia cepacia:Friend or Foe? - Jennifer L. Parke Annual Review of Microbiology Annual Review of Phytopathology Some ... In 1950 he first described the bacteria, Pseudomonas cepacia, later Burkholderia spp., responsible for causing sour skin ... This complex of at least 9 closely related species or genomovars is currently the focus of research because of their remarkable ...
BCC
... a defunct industry standards organization Burkholderia cepacia complex, a bacterial pathogen Business Controls Corporation, ...
Secondary chromosome
Burkholderia cepacia complex in 1994, Rhizobium meliloti in 1995, Bacillus thuringiensis in 1996, and now about 10% of ... Cheng, H P; Lessie, T G (1994). "Multiple replicons constituting the genome of Pseudomonas cepacia 17616". Journal of ... "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility". Proceedings of the National ... One of the largest chromids is the one in Burkholderia pseudomallei, which exceeds 3.1 million nucleotides in size, i.e. 3.1 ...
Burkholderia
... is a genus of Pseudomonadota whose pathogenic members include the Burkholderia cepacia complex, which attacks ... Burkholderia ambifaria Burkholderia anthina Burkholderia arboris Burkholderia cenocepacia Burkholderia cepacia Burkholderia ... Burkholderia dolosa Burkholderia gladioli Burkholderia glumae Burkholderia humptydooensis Burkholderia lata Burkholderia latens ... Burkholderia mallei Burkholderia metallica Burkholderia multivorans Burkholderia oklahomensis Burkholderia plantarii ...
List of MeSH codes (B03)
Burkholderia cepacia complex MeSH B03.440.400.425.251.100.110.500 - Burkholderia cepacia MeSH B03.440.400.425.251.100.355 - ... Burkholderia MeSH B03.660.075.077.100.110 - Burkholderia cepacia complex MeSH B03.660.075.077.100.110.500 - Burkholderia ... Burkholderia gladioli MeSH B03.440.400.425.251.100.477 - Burkholderia mallei MeSH B03.440.400.425.251.100.600 - Burkholderia ... Burkholderia gladioli MeSH B03.660.075.077.100.477 - Burkholderia mallei MeSH B03.660.075.077.100.600 - Burkholderia ...
Human herpesvirus 6
... à Burkholderia cepacia complex chez un nourrisson révélant une granulomatose septique et une intégration génomique du virus HHV ... Lymphohistiocytic activation syndrome and Burkholderia cepacia complex infection in a child revealing chronic granulomatous ... first identified the gene product gQ1, a glycoprotein unique to HHV-6, and found that it forms a complex with gH and gL ... Soon thereafter, another glycoprotein named gQ2 was identified and found to be part of the gH/gL/gQ1 ligand complex, forming a ...
Elaeis guineensis
Two bacterial isolates, Burkholderia cepacia (B3) and Pseudomonas aeruginosa (P3) were selected for evaluation in the ... The Oil Palm Complex: Smallholders, Agribusiness and the State in Indonesia and Malaysia. NUS Press Pte Ltd: 173/155-188/xvi+ ...
Microbial symbiosis and immunity
"Influence of Pseudomonas aeruginosa Exoproducts on Virulence Factor Production in Burkholderia cepacia: Evidence of ... Mantis, N. J.; Rol, N.; Corthésy, B. (2011-11-01). "Secretory IgA's complex roles in immunity and mucosal homeostasis in the ... "The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics". Nature Structural & ...
Colistin
Brucella Burkholderia cepacia Chryseobacterium indologenes Edwardsiella Elizabethkingia meningoseptica Francisella tularensis ... In aqueous solutions it undergoes hydrolysis to form a complex mixture of partially sulfomethylated derivatives, as well as ...
Rieske protein
X-ray structure of Rieske-type ferredoxin associated with biphenyl dioxygenase from Burkholderia cepacia PDB: 1G8J - X-ray ... Ubiquinol-cytochrome-c reductase (also known as bc1 complex or complex III) is an enzyme complex of bacterial and mitochondrial ... The complex consists of three subunits in most bacteria, and nine in mitochondria: both bacterial and mitochondrial complexes ... Rieske proteins are iron-sulfur protein (ISP) components of cytochrome bc1 complexes and cytochrome b6f complexes and are ...
Hydrocarbonoclastic bacteria
G4: The G4 pathway was observed in Bukholderia cepacia G4, where toluene is converted into o-cresol by toluene 2-monooxygenase ... Subsequently, specialists replace generalists to degrade stronger and more complex bounds; among them one of the most known ... Bacterial genera such as Gordonia, Brevibacterium, Aeromicrobium, Dietzia, Burkholderia and Mycobacterium isolated from oil ... Burkholderia sp. strain JS150 is unique in using multiple pathways for toluene metabolism: TOL pathway: This path takes the ...
Lung microbiota
Pseudomonas aeruginosa, Staphylococcus aureus, and Burkholderia cepacia are found most often in cystic fibrosis patients. High- ... The DNA-binding protein complex recognizes a discrete nucleotide sequence (5'-GGG ACT TTC T-3') in the upstream region of a ... The lung microbiota, is the pulmonary microbial community consisting of a complex variety of microorganisms found in the lower ...
Notice to Readers: Manufacturer's Recall of Nasal Spray Contaminated
with <I>Burkholderia cepacia<...
... cepacia complex. Cases of B. cepacia complex infection or colonization associated with use of this product should be reported ... Notice to Readers: Manufacturers Recall of Nasal Spray Contaminated with Burkholderia cepacia Complex. ... of intrinsic contamination with Burkholderia cepacia complex. The nasal spray is distributed as Major Twice-A-Day 12 Hour ... Clinicians should be aware that patients using product from this lot number might have been exposed to B. cepacia complex. ...
Environmental Burkholderia cepacia Complex Isolates from Human Infections - Volume 13, Number 3-March 2007 - Emerging...
Cunha MV, Leitao JH, Mahenthiralingam E, Vandamme P, Lito L, Barreto C, Molecular analysis of Burkholderia cepacia complex ... An epidemic Burkholderia cepacia complex strain identified in soil.Lancet. 2002;359:2002-3. DOIPubMedGoogle Scholar ... Taxonomy and identification of the Burkholderia cepacia complex.J Clin Microbiol. 2001;39:3427-36. DOIPubMedGoogle Scholar ... Updated version of the Burkholderia cepacia complex experimental strain panel.J Clin Microbiol. 2003;41:2797-8. DOIPubMedGoogle ...
An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and...
Burkholderia dolosa is a member of the Burkholderia cepacia complex (BCC), which is a group of bacteria that cause chronic lung ... An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and ... "An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and ...
Potential of the Burkholderia cepacia Complex to Produce 4-Hydroxy-3-Methyl-2-Alkyquinolines - EspaceINRS
... especially Burkholderia pseudomallei, Burkholderia thailandensis, Burkholderia ambifaria, and Burkholderia cepacia, are known ... Potential of the Burkholderia cepacia Complex to Produce 4-Hydroxy-3-Methyl-2-Alkyquinolines ... in the Burkholderia cepacia complex (Bcc) group. Based on the available sequence data, about one third of Bcc species carry a ... Potential of the Burkholderia cepacia Complex to Produce 4-Hydroxy-3-Methyl-2-Alkyquinolines Frontiers in Cellular and ...
IMSEAR at SEARO: Burkholderia cepacia complex: Beyond pseudomonas and acinetobacter.
Burkholderia cepacia complex (BCC) is an important nosocomial pathogen in hospitalised patients, particularly those with prior ... Gautam V, Singhal L, Ray P. Burkholderia cepacia complex: Beyond pseudomonas and acinetobacter. Indian Journal of Medical ... The International Burkholderia cepacia Working Group is open to clinicians and scientists interested in advancing knowledge of ... BCC is phenotypically unremarkable, and the complex exhibits an extensive diversity of genotypes. BCC is of increasing ...
Burkholderia cepacia complex genomovars and pulmonary transplantation outcomes in patients with cystic fibrosis - ePrints -...
B cepacia genomovars I-VII), which are collectively known as the B cepacia complex. Preoperative infection with B cepacia Is ... Burkholderia cepacia complex genomovars and pulmonary transplantation outcomes in patients with cystic fibrosis. Lookup NU ... Burkholderia cepacia is a group of organisms that comprises seven genotypically distinct species ( ... We studied archived isolates with PCR-based methods, and recorded excessive mortality in patients infected with B cepacia ...
USP Test for Burkholderia cepacia Complex | Microchem Laboratory
The USP ,60, Test for Burkholderia cepacia Compl ... Test ... The USP ,60, Test for Burkholderia cepacia Complex, like the ... specifically those in the Burkholderia cepacia Complex, a complex comprised of 20+ species of strong water-borne opportunistic ... USP ,60, tests are necessary for cosmetic and personal products to determine the absence of Burkholderia cepacia Complex. ... streaking the enriched sample onto selective media for determination of the presence or absence of Burkholderia cepacia Complex ...
Drosophila melanogaster as a model host for the Burkholderia cepacia complex. - RIIP - Réseau International des Instituts...
Evaluating the alginate oligosaccharide (OligoG) as a therapy for Burkholderia cepacia complex cystic fibrosis lung infection ...
Case Report: Community-Acquired Burkholderia cepacia Pneumonia of a Patient with Pulmonary Tuberculosis in: The American...
We report a 29-year-old female who suffered pulmonary tuberculosis and developed community-acquired Burkholderia cepacia ... Burkholderia cepacia complex in cystic fibrosis in a Brazilian reference center. Med Microbiol Immunol (Berl) 206: 447-461. ... Classification and identification of the Burkholderia cepacia complex: past, present and future. Syst Appl Microbiol 34: 87-95. ... Biocide susceptibility of the Burkholderia cepacia complex. J Antimicrob Chemother 63: 502-510. ...
Burkholderia cepacia
Environmental Burkholderia cepacia Complex Isolates from Human Infections - Volume 13, Number 3-March 2007 - Emerging...
Cunha MV, Leitao JH, Mahenthiralingam E, Vandamme P, Lito L, Barreto C, Molecular analysis of Burkholderia cepacia complex ... An epidemic Burkholderia cepacia complex strain identified in soil.Lancet. 2002;359:2002-3. DOIPubMedGoogle Scholar ... Taxonomy and identification of the Burkholderia cepacia complex.J Clin Microbiol. 2001;39:3427-36. DOIPubMedGoogle Scholar ... Updated version of the Burkholderia cepacia complex experimental strain panel.J Clin Microbiol. 2003;41:2797-8. DOIPubMedGoogle ...
Chloramphenicol Injection Products | FDA
Burkholderia cepacia Medication: Antibiotics, Cefiderocol, Ceftazidime-Avibactam
B cepacia is an organism of low virulence and is a frequent colonizer of fluids used in the hospital (eg, irrigation solutions ... Burkholderia cepacia is an aerobic gram-negative bacillus found in various aquatic environments. ... Burkholderia cepacia complex infection in a cohort of Italian patients with cystic fibrosis. J Microbiol. 2007 Jun. 45(3):275-9 ... encoded search term (Burkholderia cepacia) and Burkholderia cepacia What to Read Next on Medscape ...
Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from...
Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from ... and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from environmental and human sources. ... Dive into the research topics of Burkholderia stagnalis sp. nov. ...
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Dr Mark S Thomas | Medical School | The University of Sheffield
Thomas MS (2007) Iron acquisition mechanisms of the Burkholderia cepacia complex.. Biometals. , 20(3-4), 431-452. ... Thomas MS (2007) Iron acquisition mechanisms of the Burkholderia cepacia complex.. Biometals. , 20(3-4), 431-452. ... Thomas MS (2008) Iron acquisition mechanisms of the Burkholderia cepacia complex (BioMetals DOI: 10.1007/s10534-006-9065-4). ... Lowe CA, Asghar AH, Shalom G, Shaw JG & Thomas MS (2001) The Burkholderia cepacia fur gene: co-localization with omlA and ...
Eurosurveillance | Burkholderia stabilis outbreak associated with contaminated commercially-available washing gloves,...
Triggered by an increase in Burkholderia cepacia complex (BCC) bacteremias and the detection of BCC in unopened packages of ... We describe an outbreak of Burkholderia stabilis associated with contaminated washing gloves, a commercially available Class I ... Ausbruch mit Burkholderia-cepacia-Komplex durch kontaminierte Mundspüllösung. [Outbreak of Burkholderia cepacia complex caused ... Polyclonal outbreak of Burkholderia cepacia complex bacteraemia in haemodialysis patients. J Hosp Infect. 2003;54(2):120-3. ...
CIVCO - Review of Outbreaks of Burkholderia cepacian complex (Bcc) Associated with Contaminated Ultrasound Gel
Systematic review of ultrasound gel associated Burkholderia cepacia complex outbreaks: Clinical presentation, sources and ... Each of the 14 Burkholderia cepacian complex (Bcc) outbreaks examined was determined to have resulted from ultrasound gel that ... In this systematic review, the authors examine 14 studies pertaining to outbreaks of Burkholderia cepacian complex in ... Review of Outbreaks of Burkholderia cepacian complex (Bcc) Associated with Contaminated Ultrasound Gel. ...
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2022 PDA Pharmaceutical Microbiology Conference
14:15 , Case Studies on Burkholderia cepacia complex (BCC) Investigations and Remediation Michael J. Miller, PhD, President, ... Case studies will be presented on Burkholderia cepacia complex (BCC) related to recent product recalls, 483s, warning letters, ... Identifying and Overcoming the Challenges of Endotoxin testing of Complex Human Plasma Derived Pharmaceutical Products ...