AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsTechnology, Industry, AgricultureInformation ScienceHealth Care
Burkholderia cepaciaBurkholderia InfectionsBurkholderia cepacia complexBurkholderiaBurkholderia pseudomalleiCystic FibrosisBurkholderia cenocepaciaMelioidosisBurkholderia gladioli2,4,5-Trichlorophenoxyacetic AcidGlandersDNA, BacterialBacterial Typing TechniquesEnvironmental MicrobiologySputumOpportunistic InfectionsSequence Analysis, DNAMolecular Sequence DataPseudomonasBiodegradation, EnvironmentalBiofilmsRec A RecombinasesTobramycinRNA, Ribosomal, 16SOnionsSoil MicrobiologyRandom Amplified Polymorphic DNA TechniqueBacterial ProteinsVirulenceAnti-Bacterial AgentsPolymorphism, Restriction Fragment LengthPhylogenyGenes, BacterialDNA, RibosomalElectrophoresis, Gel, Pulsed-FieldPseudomonas aeruginosaPolymerase Chain ReactionGram-Negative Bacterial InfectionsQuorum SensingChlorophenolsTrichloroethylene4-ButyrolactonePseudomonas InfectionsPyrrolnitrinMicrobial Sensitivity TestsHydrogen CyanideMimosaCross InfectionTolueneCulture MediaSiderophoresStenotrophomonas maltophiliaGranulomatous Disease, ChronicSpecies SpecificityBacteriological TechniquesBenzethoniumCeftazidimeGene Expression Regulation, BacterialMicrobial ViabilityBase SequenceMethylomonas
Burkholderia cepacia
A species of BURKHOLDERIA considered to be an opportunistic human pathogen. It has been associated with various types of infections of nosocomial origin.
Burkholderia Infections
Infections with bacteria of the genus BURKHOLDERIA.
Burkholderia cepacia complex
A group of phenotypically similar but genotypically distinct species (genomovars) in the genus BURKHOLDERIA. They are found in water, soil, and the rhizosphere of crop plants. They can act as opportunistic human pathogens and as plant growth promoting and biocontrol agents.
Burkholderia
A genus of gram-negative, aerobic, rod-shaped bacteria. Organisms in this genus had originally been classified as members of the PSEUDOMONAS genus but overwhelming biochemical and chemical findings indicated the need to separate them from other Pseudomonas species, and hence, this new genus was created.
Burkholderia pseudomallei
A species of gram-negative, aerobic bacteria that causes MELIOIDOSIS. It has been isolated from soil and water in tropical regions, particularly Southeast Asia.
Cystic Fibrosis
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Burkholderia cenocepacia
A species of gram-negative bacteria that causes disease in plants. It is found commonly in the environment and is an opportunistic pathogen in humans.
Melioidosis
A disease of humans and animals that resembles GLANDERS. It is caused by BURKHOLDERIA PSEUDOMALLEI and may range from a dormant infection to a condition that causes multiple abscesses, pneumonia, and bacteremia.
Burkholderia gladioli
A species of gram-negative, aerobic bacteria that acts as both a human and plant pathogen.
2,4,5-Trichlorophenoxyacetic Acid
An herbicide with strong irritant properties. Use of this compound on rice fields, orchards, sugarcane, rangeland, and other noncrop sites was terminated by the EPA in 1985. (From Merck Index, 11th ed)
Glanders
A contagious disease of horses that can be transmitted to humans. It is caused by BURKHOLDERIA MALLEI and characterized by ulceration of the respiratory mucosa and an eruption of nodules on the skin.
DNA, Bacterial
Deoxyribonucleic acid that makes up the genetic material of bacteria.
Bacterial Typing Techniques
Procedures for identifying types and strains of bacteria. The most frequently employed typing systems are BACTERIOPHAGE TYPING and SEROTYPING as well as bacteriocin typing and biotyping.
Environmental Microbiology
The study of microorganisms living in a variety of environments (air, soil, water, etc.) and their pathogenic relationship to other organisms including man.
Sputum
Material coughed up from the lungs and expectorated via the mouth. It contains MUCUS, cellular debris, and microorganisms. It may also contain blood or pus.
Opportunistic Infections
An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.
Sequence Analysis, DNA
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Pseudomonas
A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.
Biodegradation, Environmental
Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.
Biofilms
Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.
Rec A Recombinases
A family of recombinases initially identified in BACTERIA. They catalyze the ATP-driven exchange of DNA strands in GENETIC RECOMBINATION. The product of the reaction consists of a duplex and a displaced single-stranded loop, which has the shape of the letter D and is therefore called a D-loop structure.
Tobramycin
An aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the PSEUDOMONAS species. It is a 10% component of the antibiotic complex, NEBRAMYCIN, produced by the same species.
RNA, Ribosomal, 16S
Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.
Onions
Herbaceous biennial plants and their edible bulbs, belonging to the Liliaceae.
Soil Microbiology
The presence of bacteria, viruses, and fungi in the soil. This term is not restricted to pathogenic organisms.
Random Amplified Polymorphic DNA Technique
Technique that utilizes low-stringency polymerase chain reaction (PCR) amplification with single primers of arbitrary sequence to generate strain-specific arrays of anonymous DNA fragments. RAPD technique may be used to determine taxonomic identity, assess kinship relationships, analyze mixed genome samples, and create specific probes.
Bacterial Proteins
Proteins found in any species of bacterium.
Virulence
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
Anti-Bacterial Agents
Substances that reduce the growth or reproduction of BACTERIA.
Polymorphism, Restriction Fragment Length
Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.
Phylogeny
The relationships of groups of organisms as reflected by their genetic makeup.
Genes, Bacterial
The functional hereditary units of BACTERIA.
DNA, Ribosomal
DNA sequences encoding RIBOSOMAL RNA and the segments of DNA separating the individual ribosomal RNA genes, referred to as RIBOSOMAL SPACER DNA.
Electrophoresis, Gel, Pulsed-Field
Gel electrophoresis in which the direction of the electric field is changed periodically. This technique is similar to other electrophoretic methods normally used to separate double-stranded DNA molecules ranging in size up to tens of thousands of base-pairs. However, by alternating the electric field direction one is able to separate DNA molecules up to several million base-pairs in length.
Pseudomonas aeruginosa
A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.
Polymerase Chain Reaction
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Gram-Negative Bacterial Infections
Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method.
Quorum Sensing
A phenomenon where microorganisms communicate and coordinate their behavior by the accumulation of signaling molecules. A reaction occurs when a substance accumulates to a sufficient concentration. This is most commonly seen in bacteria.
Chlorophenols
Phenols substituted with one or more chlorine atoms in any position.
Trichloroethylene
A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment.
4-Butyrolactone
One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.
Pseudomonas Infections
Infections with bacteria of the genus PSEUDOMONAS.
Pyrrolnitrin
3-Chloro-4-(3-chloro-2-nitrophenyl)pyrrole. Antifungal antibiotic isolated from Pseudomonas pyrrocinia. It is effective mainly against Trichophyton, Microsporium, Epidermophyton, and Penicillium.
Microbial Sensitivity Tests
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
Hydrogen Cyanide
Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
Mimosa
A plant genus of the family FABACEAE that contains kukulkanin, a CHALCONE.
Cross Infection
Any infection which a patient contracts in a health-care institution.
Toluene
A widely used industrial solvent.
Culture Media
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Siderophores
Low-molecular-weight compounds produced by microorganisms that aid in the transport and sequestration of ferric iron. (The Encyclopedia of Molecular Biology, 1994)
Stenotrophomonas maltophilia
A species of STENOTROPHOMONAS, formerly called Xanthomonas maltophilia, which reduces nitrate. It is a cause of hospital-acquired ocular and lung infections, especially in those patients with cystic fibrosis and those who are immunosuppressed.
Granulomatous Disease, Chronic
A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.
Species Specificity
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Bacteriological Techniques
Techniques used in studying bacteria.
Benzethonium
Bactericidal cationic quaternary ammonium surfactant used as a topical anti-infective agent. It is an ingredient in medicaments, deodorants, mouthwashes, etc., and is used to disinfect apparatus, etc., in the food processing and pharmaceutical industries, in surgery, and also as a preservative. The compound is toxic orally as a result of neuromuscular blockade.
Ceftazidime
Semisynthetic, broad-spectrum antibacterial derived from CEPHALORIDINE and used especially for Pseudomonas and other gram-negative infections in debilitated patients.
Gene Expression Regulation, Bacterial
Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.
Microbial Viability
Ability of a microbe to survive under given conditions. This can also be related to a colony's ability to replicate.
Base Sequence
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Methylomonas
A genus of gram-negative, aerobic, straight, curved, or branched rods which are motile by a single polar flagellum. (From Bergey's Manual of Determinative Bacteriology, 9th ed)

Lipopolysaccharide (LPS) from Burkholderia cepacia is more active than LPS from Pseudomonas aeruginosa and Stenotrophomonas maltophilia in stimulating tumor necrosis factor alpha from human monocytes. (1/432)

Whole cells and lipopolysaccharides (LPSs) extracted from Burkholderia cepacia, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Escherichia coli were compared in their ability to stimulate tumor necrosis factor alpha (TNF-alpha) from the human monocyte cell line MonoMac-6. B. cepacia LPS, on a weight-for-weight basis, was found to have TNF-alpha-inducing activity similar to that of LPS from E. coli, which was approximately four- and eightfold greater than the activity of LPSs from P. aeruginosa and S. maltophilia, respectively. The LPS-stimulated TNF-alpha production from monocytes was found to be CD14 dependent. These results suggest that B. cepacia LPS might play a role in the pathogenesis of inflammatory lung disease in cystic fibrosis, and in some patients it might be responsible, at least in part, for the sepsis-like cepacia syndrome.  (+info)

Comparison of isolation media for recovery of Burkholderia cepacia complex from respiratory secretions of patients with cystic fibrosis. (2/432)

Burkholderia cepacia selective agar (BCSA) has previously been devised for isolation of B. cepacia from respiratory secretions of patients with cystic fibrosis and tested under research laboratory conditions. Here we describe a study in which BCSA, oxidation-fermentation polymyxin bacitracin lactose agar (OFPBL), and Pseudomonas cepacia agar (PCA) were compared in routine culture procedures for the ability to grow B. cepacia and inhibit other organisms. Three hundred twenty-eight specimens from 209 patients at two pediatric centers and 328 specimens from 109 adults were tested. Plates were inoculated, incubated, and read for quality and quantity of growth at 24, 48, and 72 h. Five (1.5%) specimens from 4 (1.9%) children and 75 (22.9%) specimens from 16 (14.7%) adults grew B. cepacia complex. At 24, 48, and 72 h, BCSA achieved 43, 93, and 100% detection, respectively; OFPBL achieved 26, 84, and 96%, respectively; and PCA achieved 33, 74, and 84% detection, respectively. Quality was assessed as pinpoint or good growth. At 24 h, most cultures growing B. cepacia complex had pinpoint colonies. By 48 and 72 h, 48 and 69% of B. cepacia complex cultures, respectively, had good growth on BCSA, while on OFPBL 19 and 30%, respectively, had good growth and on PCA 11 and 18%, respectively, had good growth. BCSA was superior to OFPBL and PCA in suppressing organisms other than B. cepacia complex; 40 non-B. cepacia complex organisms were isolated from BCSA, 263 were isolated from OFPBL, and 116 were isolated from PCA. We conclude that BCSA is superior to OFPBL and PCA in its ability to support the growth of B. cepacia complex and to suppress other respiratory organisms.  (+info)

Structural elucidation of a novel exopolysaccharide produced by a mucoid clinical isolate of Burkholderia cepacia. Characterization of a trisubstituted glucuronic acid residue in a heptasaccharide repeating unit. (3/432)

The structure of the exopolysaccharide (EPS) produced by a clinical isolate of Burkholderia cepacia isolated from a patient with fibrocystic lung disease has been investigated. By means of methylation analyses, carboxyl reduction, partial depolymerization by fuming HCl and chemical degradations such as Smith degradation, lithiumethylenediamine degradation and beta-elimination, supported by GC/MS and NMR spectroscopic analyses, the repeat unit of the EPS has been identified and was shown to correspond to the acidic branched heptasaccharide with the following structure: [formula: see text]. This partially acetylated acidic polymer, distinguished by the presence of the less usual D-isomer of rhamnose and of a trisubstituted glucuronic acid residue, could represent the main EPS produced by this bacterial species.  (+info)

An epidemic of burkholderia cepacia transmitted between patients with and without cystic fibrosis. (4/432)

Burkholderia cepacia is an important pathogen in cystic fibrosis (CF) and an infrequent cause of nosocomial infection in non-CF patients. This report describes a large hospital outbreak that appeared to involve both patient groups, a previously unrecognized phenomenon. Ribotype restriction fragment length polymorphism (RFLP) profiles and pulsed-field gel electrophoresis-resolved macrochromosomal RFLPs were analyzed, a ribotype-based phylogenic tree was constructed, and case-control and cohort studies were performed. A single dominant clone was found in both CF and non-CF groups. Phylogenic analysis suggests that it has evolved independently and that such highly transmissible strains can emerge rapidly and randomly. Acquisition risk in the CF patients was linked to hospitalization (odds ratio=5.47, P=.0158, confidence interval=1. 28-26.86) and was associated with significantly increased mortality rates. Infection control policies must now consider this threat of transmission between non-CF and CF patients.  (+info)

Discrimination of Burkholderia multivorans and Burkholderia vietnamiensis from Burkholderia cepacia genomovars I, III, and IV by PCR. (5/432)

We present a PCR procedure for identification of Burkholderia cepacia, Burkholderia multivorans, and Burkholderia vietnamiensis. 16S and 23S ribosomal DNAs (rDNAs) of B. multivorans and B. vietnamiensis were sequenced and aligned with published sequences for definition of species-specific 18-mer oligonucleotide primers. Specific antisense 16S rDNA primers (for B. cepacia, 5'-AGC ACT CCC RCC TCT CAG-3'; for B. multivorans, 5'-AGC ACT CCC GAA TCT CTT-3') and 23S rDNA primers (for B. vietnamiensis, 5'-TCC TAC CAT GCG TGC AA-3') were paired with a general sense primer of 16S rDNAs (5'-AGR GTT YGA TYM TGG CTC AG-3') or with a sense primer of 23S rDNA (5'-CCT TTG GGT CAT CCT GGA-3'). PCR with these primers under optimized conditions is appropriate to specifically and rapidly identify B. multivorans, B. vietnamiensis, and B. cepacia (genomovars I, III, and IV are not discriminated). In comparison with the polyphasic taxonomic analyses presently necessary for species and genomovar identification within the B. cepacia complex, our procedure is more rapid and easier to perform and may contribute to clarifying the clinical significance of individual members of the complex in cystic fibrosis.  (+info)

Hydroxylation reaction catalyzed by the Burkholderia cepacia AC1100 bacterial strain. Involvement of the chlorophenol-4-monooxygenase. (6/432)

The Burkholderia cepacia AC1100 strain, known to degrade the herbicide, 2,4,5-Trichlorophenoxyacetic acid (2,4,5-T), is able to metabolize 4-hydroxyarylaldehyde, not only into the corresponding acid, but also into a new hydroquinone, 2,5-dihydroxyarylaldehyde. When incubated with resting AC1100 cells or cell-free extracts, syringaldehyde and 3,5-dimethoxy-4-hydroxybenzaldehyde were converted into such metabolites, identified by comparison of their mass and 1H-NMR spectra with those of authentic chemically synthesized samples. With 5-bromovanillin, only one metabolite was formed, the structure of which was identified as 2, 5-dihydroxy-4-methoxy-6-bromobenzaldehyde through 1H-NMR two-dimensional NOESY experiments. All these products result formally from a para hydroxylation of the phenol followed by the cis migration of the aldehyde. This reaction is the only one to be associated with the 2,4,5-T degradation pathway, as the acid formation was retained when the AC1100 strain had lost its degradation ability. Through competitive experiments with halophenols and methimazole, an alternative substrate of flavin monooxygenase, the chlorophenol-4-monooxygenase was recognized to be the enzyme involved in the hydroxylation of 4-hydroxyarylaldehyde. The purified enzyme, previously reported to catalyze the para hydroxylation or dehalogenating hydroxylation of chlorophenols, also promotes this hydroxylation reaction in the presence of NADH and FAD. The kcat value determined for the best substrate, syringaldehyde, 0. 08 s-1, was about 20% of that obtained for 2,6-dichlorophenol hydroxylation (0.38 s-1).  (+info)

Nitric oxide-induced potentiation of the killing of Burkholderia cepacia by reactive oxygen species: implications for cystic fibrosis. (7/432)

Burkholderia (formerly Pseudomonas) cepacia has emerged as an important pulmonary pathogen in cystic fibrosis, and survives within the lung despite a vigorous neutrophil-dominated immune response. Nitric oxide (NO) contributes to the antimicrobial activity of reactive oxygen species in the normal lung, but recent evidence suggests that inducible NO synthase is not expressed in the airway epithelial cells of cystic fibrosis (CF) patients. This may explain the failure of the neutrophil response to eliminate B. cepacia. To test this hypothesis, the present study examined the combined effect of NO, superoxide and H2O2 against B. cepacia. There was no killing of a highly transmissible strain by either superoxide or NO alone, but their combination reduced the bacterial count by >1000-fold over 75 min. This bactericidal activity was not sensitive to addition of superoxide dismutase, but was abrogated completely by catalase, suggesting that NO and hydrogen peroxide were the bactericidal mediators. Increased killing by NO in combination with H2O2 was seen for seven of a further 11 strains examined. The lack of NO in the lungs of CF patients may contribute to the survival of B. cepacia.  (+info)

Role of quinolinate phosphoribosyl transferase in degradation of phthalate by Burkholderia cepacia DBO1. (8/432)

Two distinct regions of DNA encode the enzymes needed for phthalate degradation by Burkholderia cepacia DBO1. A gene coding for an enzyme (quinolinate phosphoribosyl transferase) involved in the biosynthesis of NAD+ was identified between these two regions by sequence analysis and functional assays. Southern hybridization experiments indicate that DBO1 and other phthalate-degrading B. cepacia strains have two dissimilar genes for this enzyme, while non-phthalate-degrading B. cepacia strains have only a single gene. The sequenced gene was labeled ophE, due to the fact that it is specifically induced by phthalate as shown by lacZ gene fusions. Insertional knockout mutants lacking ophE grow noticeably slower on phthalate while exhibiting normal rates of growth on other substrates. The fact that elevated levels of quinolinate phosphoribosyl transferase enhance growth on phthalate stems from the structural similarities between phthalate and quinolinate: phthalate is a competitive inhibitor of this enzyme and the phthalate catabolic pathway cometabolizes quinolinate. The recruitment of this gene for growth on phthalate thus gives B. cepacia an advantage over other phthalate-degrading bacteria in the environment.  (+info)

Updated Version of the Burkholderia cepacia Complex Experimental Strain Panel | Journal of Clinical MicrobiologyUpdated Version of the Burkholderia cepacia Complex Experimental Strain Panel | Journal of Clinical Microbiology
The Burkholderia cepacia complex consists of nine closely related species: Burkholderia cepacia genomovars I and VI, Burkholderia multivorans (genomovar II), Burkholderia cenocepacia (genomovar III), Burkholderia stabilis (genomovar IV), Burkholderia vietnamiensis (genomovar V), Burkholderia ambifaria (genomovar VII), Burkholderia anthina (genomovar VIII), and Burkholderia pyrrocinia (genomovar IX) (2, 9, 10). Despite the advances that have been made in the understanding of the taxonomy and epidemiology of this group, infections of the respiratory tract with B. cepacia complex organisms still have a considerable impact on morbidity and mortality in cystic fibrosis (CF) patients (4, 5, 6). B. cepacia complex strains have also attracted attention as possible biocontrol and bioremediation agents that could be used as antagonists of soil-borne plant pathogens, as plant growth-promoting agents, and for the bioremediation of various recalcitrant xenobiotics (3, 8). To aid in identification, ...
https://jcm.asm.org/content/41/6/2797.long
Scientific Articles - The International Burkholderia cepacia Working Group
Glowicz J, Crist M, Gould C, Moulton-Meissner H, Noble-Wang J, de Man TJB, Perry KA, Miller Z, Yang WC, Langille S, Ross J, Garcia B, Kim J, Epson E, Black S, Pacilli M, LiPuma JJ, Fagan R, B. cepacia Investigation Workgroup. 2018. A multistate investigation of health care-associated Burkholderia cepacia complex infections related to liquid docusate sodium contamination, January-October 2016. Am J Infect Control 46:649-655.. Brooks RB, Mitchell PK, Miller JR, Vasquez AM, Havlicek J, Lee H, Quinn M, Adams E, Baker D, Greeley R, Ross K, Daskalaki I, Walrath J, Moulton-Meissner H, Crist MB, Burkholderia cepacia Workgroup. 2018. Multistate Outbreak of Burkholderia cepacia Complex Bloodstream Infections After Exposure to Contaminated Saline Flush Syringes - United States, 2016-2017. Clin Infect Dis Off Publ Infect Dis Soc Am.. Becker SL, Berger FK, Feldner SK, Karliova I, Haber M, Mellmann A, Schäfers H-J, Gärtner B. 2018. Outbreak of Burkholderia cepacia complex infections associated with ...
https://ibcwg.org/index.php/home/publications/
Taxonomy and Identification of the Burkholderia cepacia Complex | Journal of Clinical MicrobiologyTaxonomy and Identification of the Burkholderia cepacia Complex | Journal of Clinical Microbiology
At the beginning of this review it is essential to clarify the terminology that will be used to refer to the members of the Burkholderia cepacia complex and their relatives. The name B. cepacia will relate only to B. cepacia genomovar I. Strains resembling B. cepacia may belong to the B. cepacia complex, to otherBurkholderia species (for instance, Burkholderia gladioli), or to species from other genera (for instance,Ralstonia pickettii) that share some phenotypic or genotypic similarities with the B. cepacia complex. B. cepacia complex bacteria and organisms that may be confused with them will be altogether referred to as B. cepacia-like organisms. Most previous reports regarding these organisms were published before the recognition of the complicated taxonomic relationships between the different members of the B. cepacia complex; it is therefore unclear to what category the presumed B. cepacia isolates described would belong. For that reason, when such literature is cited, the name B. cepacia ...
https://jcm.asm.org/content/39/10/3427?ijkey=016117cc34c5b762756dd57266ee67d3be91427d&keytype2=tf_ipsecsha
Modeling of solvent-dependent conformational transitions in Burkholderia cepacia lipase | BMC Structural Biology | Full TextModeling of solvent-dependent conformational transitions in Burkholderia cepacia lipase | BMC Structural Biology | Full Text
The characteristic of most lipases is the interfacial activation at a lipid interface or in non-polar solvents. Interfacial activation is linked to a large conformational change of a lid, from a closed to an open conformation which makes the active site accessible for substrates. While for many lipases crystal structures of the closed and open conformation have been determined, the pathway of the conformational transition and possible bottlenecks are unknown. Therefore, molecular dynamics simulations of a closed homology model and an open crystal structure of Burkholderia cepacia lipase in water and toluene were performed to investigate the influence of solvents on structure, dynamics, and the conformational transition of the lid. The conformational transition of B. cepacia lipase was dependent on the solvent. In simulations of closed B. cepacia lipase in water no conformational transition was observed, while in three independent simulations of the closed lipase in toluene the lid gradually opened
https://bmcstructbiol.biomedcentral.com/articles/10.1186/1472-6807-9-38
WI67 11880 protein (Burkholderia cepacia) - STRING interaction networkWI67 11880 protein (Burkholderia cepacia) - STRING interaction network
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717 ...
https://string-db.org/network/292.DM42_2883
WL94 04245 protein (Burkholderia cepacia) - STRING interaction networkWL94 04245 protein (Burkholderia cepacia) - STRING interaction network
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717 ...
https://string-db.org/network/292.DM42_2586
Burkholderia cepacia complex - Infectious Disease and Antimicrobial Agents
1. Cystic Fibrosis Patient Registry, 2012 Annual Data Report Bethesda, MD: Cystic Fibrosis Foundation; 2013.. 2. Aaron SD, Ferris W, Henry DA, Speert DP, Macdonald NE. Multiple combination bactericidal antibiotic testing for patients with cystic fibrosis infected with Burkholderia cepacia. American journal of respiratory and critical care medicine 2000;161:1206-12. [PubMed]. 3. Aaron SD, Vandemheen KL, Ferris W, Fergusson D, Tullis E, Haase D, Berthiaume Y, Brown N, Wilcox P, Yozghatlian V, Bye P, Bell S, Chan F, Rose B, Jeanneret A, Stephenson A, Noseworthy M, Freitag A, Paterson N, Doucette S, Harbour C, Ruel M, MacDonald N. Combination antibiotic susceptibility testing to treat exacerbations of cystic fibrosis associated with multiresistant bacteria: a randomised, double-blind, controlled clinical trial. Lancet 2005;366:463-71. [PubMed]. 4. Avgeri SG, Matthaiou DK, Dimopoulos G, Grammatikos AP, Falagas ME. Therapeutic options for Burkholderia cepacia infections beyond co-trimoxazole: a ...
http://www.antimicrobe.org/b19.asp
Enantioselectivity of Pseudomonas cepacia lipase towards 2-methyl-3(or 4)-arylalkanols: An approach based on the...Enantioselectivity of Pseudomonas cepacia lipase towards 2-methyl-3(or 4)-arylalkanols: An approach based on the...
For a better understanding of the previously reported enantioselectivity of Pseudomonas cepacia lipase (PCL) in acylation of racemic primary alcohols, 2-methyl-3(or 4)-arylalkanols, molecular modeling of tetrahedral intermediates (TIs) at the active site was performed. The most probable conformers of TIs were elucidated and their interactions with the amino acid residues of the binding pockets at the enzyme active site were studied. The free energy difference between TIs of two enantiomers was approximated by the differences in potential energy and the solvent accesible surface area. Correlation between the HE(His286). . .O gamma (Ser87) hydrogen bond differences of diastereomeric, low energy gauche-TIs, and experimentally determined enantiomeric ratios was found. In agreement with the stereoelectronic theory, the gauche-TI precedes ester release.. ...
http://fulir.irb.hr/991/
Burkholderia cepacia (Palleroni and Holmes) Yabuuchi et al. ATCC ®Burkholderia cepacia (Palleroni and Holmes) Yabuuchi et al. ATCC ®
Burkholderia cepacia ATCC ® 17616D-5™ Designation: Genomic DNA from Burkholderia cepacia strain 249 TypeStrain=False Application:
https://www.atcc.org/Products/All/17616D-5.aspx?p=1&rel=%7B0%7D
Burkholderia cepacia (Palleroni and Holmes) Yabuuchi et al. ATCC ®Burkholderia cepacia (Palleroni and Holmes) Yabuuchi et al. ATCC ®
Burkholderia cepacia ATCC ® 17616D-5™ Designation: Genomic DNA from Burkholderia cepacia strain 249 TypeStrain=False Application:
https://www.atcc.org/Global/Products/B/8/9/4/17616D-5.aspx
Whole genome sequencing enables the characterization of BurI, a LuxI homologue of Burkholderia cepacia strain GG4 [PeerJ]Whole genome sequencing enables the characterization of BurI, a LuxI homologue of Burkholderia cepacia strain GG4 [PeerJ]
Quorum sensing is a mechanism for regulating proteobacterial gene expression in response to changes in cell population. In proteobacteria, N-acyl homoserine lactone (AHL) appears to be the most widely used signalling molecules in mediating, among others, the production of extracellular virulence factors for survival. In this work, the genome of B. cepacia strain GG4, a plasmid-free strain capable of AHL synthesis was explored. In silico analysis of the 6.6 Mb complete genome revealed the presence of a LuxI homologue which correspond to Type I quorum sensing. Here, we report the molecular cloning and characterization of this LuxI homologue, designated as BurI. This 609 bp gene was cloned and overexpressed in Escherichia coli BL21(DE3). The purified protein was approximately 25 kDa and is highly similar to several autoinducer proteins of the LuxI family among Burkholderia species. To verify the AHL synthesis activity of this protein, high resolution liquid chromatography-mass spectrometry analysis
https://peerj.com/articles/1117/
Hong Kong investigates invasive Burkholderia cepacia cluster - Outbreak News TodayHong Kong investigates invasive Burkholderia cepacia cluster - Outbreak News Today
The affected persons involved eight males and one female aged 46 to 69, who were admitted to Caritas Medical Centre from February 2017 to August 2018 respectively for management. Among them, seven were discharged, one remains hospitalized and one passed away in 2017.. The clinical diagnoses of the patients were infective spondylitis (4), sepsis (2), septic arthritis (2) and infective endocarditis (1).. Separately, the Burkholderia cepacia isolates from seven of the nine patients were found to be genetically identical upon laboratory testing.. Preliminary investigation revealed that all affected patients were people who injected drugs. Investigations are ongoing, a health department spokesman said.. Burkholderia cepacia is a bacteria which are commonly found in water, soil, and moist environments. It is generally not pathogenic to healthy person but those who have weakened immune system or chronic lung diseases may be more susceptible to infection with the bacteria.. The spokesman appealed that ...
http://outbreaknewstoday.com/hong-kong-investigates-invasive-burkholderia-cepacia-cluster-40830/
Which antibiotics are best to treat worsening symptoms in people with cystic fibrosis with persistent Burkholderia cepacia...Which antibiotics are best to treat worsening symptoms in people with cystic fibrosis with persistent Burkholderia cepacia...
Review question We looked for evidence of which antibiotics are best to treat a flare up of symptoms in people with cystic fibrosis with persistent Burkholderia cepacia complex lung infection.. Background Cystic fibrosis is a common inherited condition where the lungs often become blocked with mucus. This harms the lungs defences and often results in chronic, persistent infections that cannot be cleared by antibiotics. People with cystic fibrosis often need courses of antibiotics to reduce their symptoms (for instance cough, excess mucus and breathlessness) when these flare up or worsen. Such episodes are called exacerbations, and are usually treated with intravenous antibiotics (given through a drip into a vein). One group of bacteria that can infect the lungs of people with cystic fibrosis is called the Burkholderia cepacia complex. These closely-related bacteria are found widely in the environment and do not cause infections in healthy people who do not have cystic fibrosis. They are ...
http://www.cochrane.org/CD009529/CF_which-antibiotics-are-best-treat-worsening-symptoms-people-cystic-fibrosis-persistent-burkholderia
Endemic Burkholderia cepacia bacteraemia: Clinical features and antimicrobial susceptibilities of isolates<...
TY - JOUR. T1 - Endemic Burkholderia cepacia bacteraemia. T2 - Clinical features and antimicrobial susceptibilities of isolates. AU - Yu, Wen Liang. AU - Wang, Der Yuan. AU - Lin, Cheng Wen. AU - Tsou, Mei Fen. PY - 1999. Y1 - 1999. N2 - Burkholderia cepacia has emerged as a nosocomial pathogen, causing numerous outbreaks, particularly among cystic fibrosis (CF) patients. Reports of clinical features of endemic B. cepacia bacteraemia in non-CF patients are rare. Twenty-five patients with B. cepacia bacteraemia were matched with 25 controls with nosocomial Escherichia coli bacteraemia at China Medical College Hospital, Taichung, Taiwan, over a period of 3 y. Case-patients included 16 men and 9 women, from 13 to 75 y. All had severe underlying diseases, most commonly malignancy (44%). Twenty-four patients (96%) had nosocomial infections. Five patients (20%) had polymicrobial bacteraemia. Our controls included 11 men and 14 women, age range 18-80 y. The most common underlying disease was malignancy ...
https://tmu.pure.elsevier.com/en/publications/endemic-burkholderia-cepacia-bacteraemia-clinical-features-and-an
Two cases of Burkholderia cepacia endophthalmitis | British Journal of OphthalmologyTwo cases of Burkholderia cepacia endophthalmitis | British Journal of Ophthalmology
Although Staphylococcus epidermidis is responsible for the majority of cases after cataract surgery, any bacteria may cause postoperative endophthalmitis. Burkholderia cepacia (previously known as Pseudomonas cepacia) is a Gram negative, oxidase positive, non-fermentative bacilli. Burkholderia cepacia does cause significant infection not only in cystic fibrosis, chronic granulomatous disease, and immunocompromised patients, but also in healthy individuals.1 It has been shown to be resistant to some antiseptics such as benzalkonium chloride, clorhexidine at standard or high concentrations, and even be alive in those antiseptics.2. ...
https://bjo.bmj.com/content/90/9/1211.1
Treatments to cure long-term infections with Burkholderia cepacia in people with cystic fibrosis | CochraneTreatments to cure long-term infections with Burkholderia cepacia in people with cystic fibrosis | Cochrane
Review question. We reviewed the evidence for antibiotic treatment to cure early infection with Burkholderia cepacia complex in people with cystic fibrosis and prevent it becoming permanent.. Background. Cystic fibrosis is an inherited disease and people who have this disease produce large amounts of thick mucus which is difficult to clear. This mucus blocks up their lungs and digestive systems. People with cystic fibrosis suffer from lots of chest infections, which cause scarring of their airways. Eventually, they develop infections that cant be cured with antibiotics, so their lungs always contain lots of bugs, this is described as being chronically infected. One of these bugs, Burkholderia cepacia, causes a lot of problems for people with cystic fibrosis because it is very difficult to treat and makes their lung disease deteriorate faster than it otherwise would. This is an updated version of the review.. Search date. We last searched for any evidence on 12 March 2019.. Study ...
https://www.cochrane.org/CD009876/CF_treatments-cure-long-term-infections-burkholderia-cepacia-people-cystic-fibrosis
Iatrogenic postoperative spondylodiscitis attributed to Burkholderia cepacia infection in an immunocompetent patientIatrogenic postoperative spondylodiscitis attributed to Burkholderia cepacia infection in an immunocompetent patient
CONCLUSION: Rarely, B. cepacia may be the offending organism resulting in a postoperative lumbar PS.PMID:33948309 | PMC:PMC8088530 | DOI:10.25259/SNI_518_2020...
https://medworm.com/885940117/iatrogenic-postoperative-spondylodiscitis-attributed-to-em-burkholderia-cepacia-em-infecti/
Commercial Use of Burkholderia cepacia - Volume 5, Number 2-April 1999 - Emerging Infectious Diseases journal - CDC
To the Editor: In their review of the potential threat to human health by the commercial use of Burkholderia cepacia, Holmes et al. (1) focus on the biopesticidal uses of this bacterium in agriculture. By virtue of its ability to antagonize a number of soilborne plant pathogens, B. cepacia is an attractive natural alternative to currently used chemical pesticides, such as captan, mancozeb, and metalaxyl. The replacement of these highly toxic agents, which are among the mainstays of crop protection chemicals, by safer products is a laudable goal. However, despite being nonpathogenic to healthy humans (and thus classified as a Biosafety Level 1 species), B. cepacia can cause life-threatening pulmonary infection in persons with cystic fibrosis. Holmes et al. call for a moratorium on the use of B. cepacia in agriculture until more is known about risks from such use.. Perhaps of greater concern than agricultural use is B. cepacias use as a bioremedial agent. Holmes et al. only briefly refer to the ...
https://wwwnc.cdc.gov/eid/article/5/2/99-0226_article
Characterization of the penA and penR genes of Burkholderia cepacia 249 which encode the chromosomal class A penicillinase and...Characterization of the penA and penR genes of Burkholderia cepacia 249 which encode the chromosomal class A penicillinase and...
Burkholderia cepacia is recognized as an important pathogen in the lung infections of patients with cystic fibrosis. An inducible beta-lactamase activity has been associated with increased resistance to beta-lactam antibiotics in clinical isolates of B. cepacia. In this study, we report the revised sequence of the penA gene, which encodes the inducible penicillinase of B. cepacia, and show that it belongs to the molecular class A beta-lactamases and exhibits a high degree of similarity to the chromosomal beta-lactamase of Klebsiella oxytoca. Analysis of the nucleotide sequence of the DNA region directly upstream of the penA coding sequence revealed an open reading frame (penR), the transcription of which was oriented opposite to that of penA and whose initiation was 130 bp away from that of penA. Two potential ribosome-binding sites and two overlapping -10 and -35 promoter sequences were identified in the intercistronic region. The predicted translation product of penR was a polypeptide of 301 ...
https://aac.asm.org/content/41/11/2399?ijkey=8e7262f80430b711383f07dcd84b17c67c2ab65e&keytype2=tf_ipsecsha
British Library EThOS: Antimicrobial strategies against Burkholderia cepaciaBritish Library EThOS: Antimicrobial strategies against Burkholderia cepacia
The aim of this project was to investigate novel antimicrobial strategies against B. cepacia, based on natural antimicrobial compounds present in plants and human airways as protection against bacterial disease. The project focused on a panel of 20 strains of B. cepacia complex. Isolates included strains representing major epidemic clones of B. cepacia and exhibiting a range of susceptibilities to all classes of conventional antibiotics. The project is focused on two major themes. First, a study of antimicrobials from plants and second, examination of the antimicrobial activities of cationic peptides present in human airway secretions. The susceptibility of the B. cepacia strain panel to plant extracts was investigated, in particular the activity of aqueous garlic extract (AGE) and thyme oil. The MIC of thyme oil for all 20 strains was found to be 0.01%. MICs of AGE ranged from 0.25%-3%. Killing curves suggesting that AGE produces a slow killing effect over a twenty four hour period, whereas ...
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.657471
Enzymatic resolution of (±)-cis-2-aminocyclopentanol and (±)-cis-2- aminocyclohexanol<...
TY - JOUR. T1 - Enzymatic resolution of (±)-cis-2-aminocyclopentanol and (±)-cis-2- aminocyclohexanol. AU - Luna, Amparo. AU - Astorga, Covadonga. AU - Fülöp, F.. AU - Gotor, Vicente. PY - 1998/12/24. Y1 - 1998/12/24. N2 - (±)-cis-N-Benzyloxycarbonyl-2-aminocyclopentanol was efficiently resolved by O-acylation with Pseudomonas cepacia lipase, as was (±)-cis-N- benzyloxycarbonyl-2-aminocyclohexanol when Candida antarctica lipase was used.. AB - (±)-cis-N-Benzyloxycarbonyl-2-aminocyclopentanol was efficiently resolved by O-acylation with Pseudomonas cepacia lipase, as was (±)-cis-N- benzyloxycarbonyl-2-aminocyclohexanol when Candida antarctica lipase was used.. UR - http://www.scopus.com/inward/record.url?scp=0032564662&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0032564662&partnerID=8YFLogxK. U2 - 10.1016/S0957-4166(98)00482-0. DO - 10.1016/S0957-4166(98)00482-0. M3 - Article. AN - SCOPUS:0032564662. VL - 9. SP - 4483. EP - 4487. JO - Tetrahedron Asymmetry. JF - ...
https://hungary.pure.elsevier.com/en/publications/enzymatic-resolution-of-cis-2-aminocyclopentanol-and-cis-2-aminoc
Induction of biologically active interleukin-8 from lung epithelial cells by Burkholderia (Pseudomonas) cepacia products. |...Induction of biologically active interleukin-8 from lung epithelial cells by Burkholderia (Pseudomonas) cepacia products. |...
The frequency of isolation of Burkholderia cepacia from the sputum of cystic fibrosis (CF) patients is increasing. Using the human A549 lung epithelial cell line, we have investigated the ability of B. cepacia exoproducts to stimulate interleukin-8 (IL-8) release. Cell-free supernatants from a panel of CF clinical, non-CF clinical, and nonclinical B. cepacia isolates were found to stimulate IL-8 release, with levels ranging from 11.8 +/- 2.8 to 80.0 +/- 3.5 ng/ml. A similar pattern was seen at the level of the IL-8 mRNA. The bioactivity of the IL-8 was confirmed by examining its effect on the intracellular free calcium in neutrophils and inhibition by a neutralizing anti-IL-8 antibody. B. cepacia lipopolysaccharide, which was able to stimulate IL-8 release from monocytes, did not release IL-8 from the A549 cells. Furthermore, the stimulating ability of the bacterial cell-free supernatant was not diminished by polymyxin B, was markedly reduced by boiling, and appeared unrelated to ...
https://iai.asm.org/content/65/2/617
Items where Author is Nicholson, Audrey - Northumbria Research LinkItems where Author is Nicholson, Audrey - Northumbria Research Link
Nicholson, Audrey, Perry, John, James, Arthur, Stanforth, Stephen, Carnell, Sonya, Wilkinson, Kathryn, Khan, Anjam, de Soyza, Anthony and Gould, Kate (2012) In vitro activity of S-(3,4-dichlorobenzyl) isothiourea hydrochloride and novel structurally related compounds against multidrug-resistant bacteria, including Pseudomonas aeruginosa and Burkholderia cepacia complex. International Journal of Antimicrobial Agents, 39 (1). pp. 27-32. ISSN 0924-8579 de Soyza, Anthony, Meachery, Gerard, Hester, Katy, Nicholson, Audrey, Parry, Gareth, Tocewicz, Krzysztof, Pillay, Thasee, Clark, Stephen, Lordan, James, Schueler, Stephan, Fisher, Andrew, Dark, John, Gould, Kate and Corris, Paul (2010) Lung transplantation for patients with cystic fibrosis and Burkholderia cepacia complex infection: A single-center experience. The Journal of Heart and Lung Transplantation, 29 (12). pp. 1395-1404. ISSN 1053 2498 Meachery, Gerard, de Soyza, Anthony, Nicholson, Audrey, Parry, Gareth, Hasan, Asif, Tocewicz, Krzysztof, ...
http://nrl.northumbria.ac.uk/view/creators/Nicholson=3AAudrey=3A=3A.html
Nurse Assist recalls I.V. Flush Syringes: Possibly linked to Burkholderia cepacia outbreak - Outbreak News TodayNurse Assist recalls I.V. Flush Syringes: Possibly linked to Burkholderia cepacia outbreak - Outbreak News Today
Nurse Assist voluntarily recalled its I.V. Flush Syringes after becoming aware of patients that developed Burkholderia cepacia bloodstream infections while receiving intravenous care using prepackaged saline flushes from Nurse Assist. Nurse Assist is notifying its distributors and customers via email, phone call, and certified mail. Customers will receive instructions for returning product. For freight collect shipping information, please contact the Customer Service Team at 1-800-649-6800 ext. 10.. Nurse Assist is actively investigating the possible link to the infections with the Food and Drug Administration, the U.S. Centers for Disease Control, and various state health departments to ensure that the products are safe for their intended use. Until an investigation can be completed, Nurse Assist urges all healthcare facilities with affected product to discontinue use and return the product to the supplier.. Consumers with questions may contact the company via telephone at 1-800-649-6800 ext. ...
http://outbreaknewstoday.com/nurse-assist-recalls-i-v-flush-syringes-possibly-linked-to-burkholderia-cepacia-outbreak-80147/
In Situ Hybridization of Burkholderia Cepacia CellsIn Situ Hybridization of Burkholderia Cepacia Cells
McNamara, Christopher J.; Leff, Laura Gunn (2002). In Situ Hybridization of Burkholderia Cepacia Cells. Humana Press 187-192. doi: 10.1385/1-59259-238-4:187. Retrieved from https://oaks.kent.edu/bscipubs/ ...
https://oaks.kent.edu/bscipubs/127
https://www.thefreelibrary.com/Environmental+Burkholderia+cepacia+complex+isolates+in+human...-a0161011310https://www.thefreelibrary.com/Environmental+Burkholderia+cepacia+complex+isolates+in+human...-a0161011310
Free Online Library: Environmental Burkholderia cepacia complex isolates in human infections.(DISPATCHES) by Emerging Infectious Diseases; Health, general Infection Health aspects
https://www.thefreelibrary.com/Environmental+Burkholderia+cepacia+complex+isolates+in+human...-a0161011310
Lung Transplantation for Cystic Fibrosis (CF); the Effect of Burkholderia Cepacia Genomovars on Outcomes | Clinical ScienceLung Transplantation for Cystic Fibrosis (CF); the Effect of Burkholderia Cepacia Genomovars on Outcomes | Clinical Science
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http://www.clinsci.org/content/100/s44/2P.3
Successful containment of a nosocomial outbreak of Burkholderia cepacia in a special care baby unit of a base hospital in Sri...Successful containment of a nosocomial outbreak of Burkholderia cepacia in a special care baby unit of a base hospital in Sri...
Over 6 days in May 2013, 4 BCs out of 14 in the special care baby unit of Base Hospital Avissawella, grew B. cepacia. BCs became positive after a mean of 3.5 days since admission. All four neonates developed high levels of inflammatory markers and thrombocytopaenia. Organism showed identical ABs in all isolates, with sensitivity to meropenem, ceftazidime, ciprofloxacin and resistance to trimethoprim and aminoglycosides. All babies were successfully treated with meropenem.. A 10% dextrose solution used for the neonates grew B. Cepacia on culture. This solution is not readily available in our setting and its prepared in the unit, using 5% and 50% dextrose combination. It was used for different babies at multiple times throughout the day by several nurses. Other samples that grew B. cepacia included a bottle of normal saline used as a multiple dose vial for preparation of intravenous (IV) drugs, a gallipot of sterile water used for suction of airway of a ventilated baby, 2 incubator humidifiers ...
https://0-aricjournal-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/2047-2994-4-S1-P264
EC 1.6.5.7EC 1.6.5.7
Accepted name: 2-hydroxy-1,4-benzoquinone reductase. Reaction: 2-hydroxy-1,4-benzoquinone + NADH + H+ = hydroxyquinol + NAD+. For diagram of reaction click here.. Glossary: hydroxyquinol = 1,2,4-trihydroxybenzene. Other name(s): hydroxybenzoquinone reductase; 1,2,4-trihydroxybenzene:NAD oxidoreductase; NADH:2-hydroxy-1,4-benzoquinone oxidoreductase. Systematic name: NADH:2-hydroxy-1,4-benzoquinone oxidoreductase. Comments: A flavoprotein (FMN) that differs in substrate specificity from other quinone reductases. The enzyme in Burkholderia cepacia is inducible by 2,4,5-trichlorophenoxyacetate.. Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 214466-94-1. References:. 1. Zaborina, O., Daubaras, D.L., Zago, A., Xun, L., Saido, K., Klem,T., Nikolic, D. and Chakrabarty, A.M. Novel pathway for conversion of chlorohydroxyquinol to maleylacetate in Burkholderia cepacia AC1100. J. Bacteriol. 180 (1998) 4667-4675. [PMID: 9721310]. ...
http://www.sbcs.qmul.ac.uk/iubmb/enzyme/EC1/6/5/7.html
Nucleotide sequence analysis of a gene from Burkholderia (Pseudomonas) cepacia encoding an outer membrane lipoprotein involved...Nucleotide sequence analysis of a gene from Burkholderia (Pseudomonas) cepacia encoding an outer membrane lipoprotein involved...
Antibiotic-resistant Burkholderia (Pseudomonas) cepacia is an important etiologic agent of nosocomial and cystic fibrosis infections. The primary resistance mechanism which has been reported is decreased outer membrane permeability. We previously reported the cloning and characterization of a chloramphenicol resistance determinant from an isolate of B. cepacia from a patient with cystic fibrosis that resulted in decreased drug accumulation. In the present studies we subcloned and sequenced the resistance determinant and identified gene products related to decreased drug accumulation. Additional drug resistances encoded by the determinant include resistances to trimethoprim and ciprofloxacin. Sequence analysis of a 3.4-kb subcloned fragment identified one complete and one partial open reading frame which are homologous with two of three components of a potential antibiotic efflux operon from Pseudomonas aeruginosa (mexA-mexB-oprM). On the basis of sequence data, outer membrane protein analysis, ...
https://aac.asm.org/content/40/2/307?ijkey=8aef9651ddcb8a7eae8f2c87c14cb3d947438148&keytype2=tf_ipsecsha
Pre GI: Gene
General Information: Burkholderia cenocepacia MC0-3 was isolated from soil associated with maize roots. This species (genomovar III) is part of the Burkholderia cepacia complex, which consists of 9 closely related species, also known as genomovars. These organisms are commonly found in soil and all are opportunistic pathogens espcially in cystic fibrosis patients. ...
http://pregi.bi.up.ac.za/pre_gi_gene.php?source_accession=NC_010515&gi_accession=NC_010515:1491590
Racemase Activity of B. cepacia Lipase Leads to Dual-Function Asymmetric Dynamic Kinetic Resolution of alpha-AminonitrilesRacemase Activity of B. cepacia Lipase Leads to Dual-Function Asymmetric Dynamic Kinetic Resolution of alpha-Aminonitriles
The Diels-Alder reaction is one of the most powerful synthetic tools in organic chemistry, and asymmetric Diels-Alder catalysis allows for rapid construction of chiral carbon scaffolds. For this reason, considerable effort has been invested in developing efficient and stereoselective organo- and biocatalysts. However, Diels-Alder is a virtually unknown reaction in Nature, and to engineer an enzyme into a Diels-Alderase is therefore a challenging task. Despite several successful designs of catalytic antibodies since the 1980s, their catalytic activities have remained low, and no true artificial Diels-Alderase enzyme was reported before 2010.. In this thesis, we employ state-of-the-art computational tools to study the mechanism of organocatalyzed Diels-Alder in detail, and to redesign existing enzymes into intermolecular Diels-Alder catalysts. Papers I-IV explore the mechanistic variations when employing increasingly activated reactants and the effect of catalysis. In particular, the ...
http://kth.diva-portal.org/smash/record.jsf?pid=diva2%3A432472&c=15&searchType=SIMPLE&language=en&query=&af=%5B%5D&aq=%5B%5B%7B%22personId%22%3A%22u15c1cql%22%7D%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
Pre GI: SWBIT SVG BLASTN
General Information: This organism (AU 1054) was isolated from the blood of a patient with CF. This microbe has three chromosomes. Opportunistic pathogen. This species (genomovar III) is part of the Burkholderia cepacia complex, which consists of 9 closely related species, also known as genomovars. These organisms are commonly found in soil and all are opportunistic pathogens espcially in cystic fibrosis patients. ...
http://pregi.bi.up.ac.za/pre_gi_swbit.php?blast=blastn&query=NC_008060:1346581&subject=NC_008391:699222
Interspecies communication between Burkholderia cepacia and Pseudomonas aeruginosa. - PubMed - NCBIInterspecies communication between Burkholderia cepacia and Pseudomonas aeruginosa. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/12381027
Burkholderia cepacia NCTC 10661 | TM Media - Titan Biotech Ltd.Burkholderia cepacia NCTC 10661 | TM Media - Titan Biotech Ltd.
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https://www.tmmedia.in/content/burkholderia-cepacia-nctc-10661
Verapamil-Tobramycin Synergy in <em>Pseudomonas cepacia</em> but Not < by Robert C. Cohn, Lois...Verapamil-Tobramycin Synergy in <em>Pseudomonas cepacia</em> but Not < by Robert C. Cohn, Lois...
Virtually all patients with cystic fibrosis (CF) die of respiratory failure resulting from chronic progressive pulmonary infections. Pseudomonas aeruginosa and Pseudomonas (Burkholderia) cepacia are the two major bacterial pathogens responsible for the pulmonary deterioration in these patients. Tobramycin has variable inhibitory effects on these organisms, but in many isolates this inhibition is increased in vitro by exposure to the diuretic, amiloride. Aerosolized amiloride has been shown to be of clinical benefit in CF. The basis for this synergy is unknown. To examine the possibility that amiloride-tobramycin synergy is mediated through a bacterial efflux mechanism mediated by a multidrug resistant (MDR) protein, we studied the inhibitory effect of verapamil, a known MDR inhibitor on the tobramycin MIC in P. aeruginosa and P. cepacia using standard MIC and synergy testing. Verapamil had no effect on the tobramycin MIC in P. aeruginosa but was able to act synergistically with tobramycin in reducing
https://corescholar.libraries.wright.edu/ncbp/706/
Social interactions in the Burkholderia cepacia complex: biofilms and quorum sensing. - Semantic ScholarSocial interactions in the Burkholderia cepacia complex: biofilms and quorum sensing. - Semantic Scholar
Burkholderia cepacia complex bacteria are opportunistic pathogens that cause respiratory tract infections in susceptible patients, mainly people with cystic fibrosis. There is convincing evidence that B. cepacia complex bacteria can form biofilms, not only on abiotic surfaces (e.g., glass and plastics), but also on biotic surfaces such as epithelial cells, leading to the suggestion that biofilm formation plays a key role in persistent infection of cystic fibrosis lungs. This article presents an overview of the molecular mechanisms involved in B. cepacia complex biofilm formation, the increased resistance of sessile B. cepacia complex cells and the role of quorum sensing in B. cepacia complex biofilm formation.
https://www.semanticscholar.org/paper/Social-interactions-in-the-Burkholderia-cepacia-co-Coenye/a43dd7fe5d1840c2cf96112de121d185a59299c6
Pseudomonas cepacia | definition of Pseudomonas cepacia by Medical dictionaryPseudomonas cepacia | definition of Pseudomonas cepacia by Medical dictionary
Looking for online definition of Pseudomonas cepacia in the Medical Dictionary? Pseudomonas cepacia explanation free. What is Pseudomonas cepacia? Meaning of Pseudomonas cepacia medical term. What does Pseudomonas cepacia mean?
https://medical-dictionary.thefreedictionary.com/Pseudomonas+cepacia
A General Protein O-glycosylation System Within the Burkholderia Cepacia Complex Is Involved in Motility and Virulence - PubMedA General Protein O-glycosylation System Within the Burkholderia Cepacia Complex Is Involved in Motility and Virulence - PubMed
Bacteria of the Burkholderia cepacia complex (Bcc) are pathogens of humans, plants, and animals. Burkholderia cenocepacia is one of the most common Bcc species infecting cystic fibrosis (CF) patients and its carriage is associated with poor prognosis. In this study, we characterized a general O-link …
https://pubmed.ncbi.nlm.nih.gov/24673753/
Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis | European Cystic Fibrosis Society (ECFS)Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis | European Cystic Fibrosis Society (ECFS)
Regan KH, Bhatt J. Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis. Cochrane Database of Systematic Reviews 2016, Issue 11. Art. No.: CD009876. DOI: 10.1002/14651858.CD009876.pub3 ...
https://www.ecfs.eu/resource-article/cf-literature/eradication-therapy-burkholderia-cepacia-complex-people-cystic
Azithromycin in Patients With CF, Infected With Burkholderia Cepacia Complex - Full Text View - ClinicalTrials.govAzithromycin in Patients With CF, Infected With Burkholderia Cepacia Complex - Full Text View - ClinicalTrials.gov
Pulmonary infection with Burkholderia cepacia complex (BCC) in patients with CF is often associated with a more rapid decline in lung function. Because of the resistance of BCC to many antibiotics, treatment options are often limited. New therapies to improve outcomes for patients infected with BCC are needed.. However, because of the unpredictable nature of this pulmonary infection in CF, patients with BCC infection have been excluded from many CF therapeutic trials.. Recent published trials in the United States, Australia, and the United Kingdom have all demonstrated clinical benefits from prolonged administration of azithromycin in CF. In these trials, the vast majority of patients were chronically infected with Pseudomonas aeruginosa.. Patients with BCC were excluded from the US and UK trials, and only four patients with BCC infection were enrolled in the Australian trial. Thus, the effectiveness of azithromycin in CF patients infected with BCC is largely unknown and deserves further ...
https://clinicaltrials.gov/ct2/show/NCT00298922
ফার্মাসিউটিক্যালে নতুন উদ্বেগের নাম Burkholderia cepacia complex (Bcc) - PharmaBanglaফার্মাসিউটিক্যালে নতুন উদ্বেগের নাম Burkholderia cepacia complex (Bcc) - PharmaBangla
Burkholderia cepacia complex (Bcc) গ্রাম নেগেটিভ, অ্যারোবিক (অক্সিজেনের উপস্থিতিতে বাঁচতে পারে) ব্যাক্টেরিয়া
https://pharmabangla.com/article/2690
Burkholderia cepacia complex | Johns Hopkins ABX GuideBurkholderia cepacia complex | Johns Hopkins ABX Guide
Burkholderia cepacia complex answers are found in the Johns Hopkins ABX Guide powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540069/all/Burkholderia_cepacia_complex?q=Disease+Wilson
Development of Galleria mellonella as an Alternative Infection Model for the Burkholderia cepacia Complex | Infection and...Development of Galleria mellonella as an Alternative Infection Model for the Burkholderia cepacia Complex | Infection and...
In this study, we compare our results for a G. mellonella infection model with previously published BCC data from other infection models, taking care to use many of the identical BCC strains previously tested in order to ensure valid comparison. We observed that G. mellonella, as an infection model for the BCC, possessed several advantages over other infection models. Using G. mellonella, we obtained similar results to both mouse and other alternative infection models with identical BCC strains. In our experience, no other alternative infection models as tested were as sensitive, accurate (with respect to mice and rat lung model results), or as robust or simple to use as the G. mellonella model. This was despite the fact G. mellonella possesses a relatively complex innate immune response, which is lacking in plant infection models. Furthermore, due to ethical and regulatory issues, it is now difficult to perform LD50 experiments with mice. In addition, amoebae and C. elegans are somewhat more ...
https://iai.asm.org/content/76/3/1267?ijkey=55ffb420be3df92e84f74530906f85e6b3229fc4&keytype2=tf_ipsecsha
Download Efectos Del Cambio Climático En Las Costas De Chile 2009
Appl Environ Microbiol 68: 173-180. Wang H, Marjomaki Book, Ovod Deal, Kulomaa MS( 2002) Numic purification of part iron in Sphingobium Palace ATCC 39723. Biochem Biophys Res Commun 299: 703-709. Nakamura haben, Motoyama file, Hirono S, Yamaguchi I( 2004) Identification, 4:00PM, and Fourth agriculture of inorganic book survey. Biochim Biophys Acta 1700: 151-159. Martin-Le Garrec G, Artaud I, Capeillere-Blandin C( 2001) war and ineffective pictures of the importance body from Burkholderia cepacia interpretation AC1100. Biochim Biophys Acta 1547: 288-301. Webb BN, Ballinger JW, Kim E, Belchik SM, Lam KS, Youn B, Nissen MS, Xun LY, Kang C( 2010) Characterization of Chlorophenol 4-Monooxygenase( TftD) and NADH: capitalism Oxidoreductase( TftC) of Burkholderia cepacia AC1100. Gisi MR, Xun LY( 2003) Characterization of chlorophenol 4-monooxygenase( TftD) and NADH: download Efectos del cambio climático en las costas de Chile 2009 deterioration physiology distress( TftC) of Burkholderia cepacia AC1100. ...
http://sapernoviak.website.pl/library.php?q=download-Efectos-del-cambio-clim%C3%A1tico-en-las-costas-de-Chile-2009/
Pharmaceutical Microbiology Resources: Burkholderia cepacia - Risks in Context for Non-Sterile Pharmaceutical Products (Webinar)
Burkholderia cepacia complex (BCC) organisms can survive or multiply in a variety of non-sterile and water-based products because it is resistant to certain preservatives and antimicrobial agents. This makes the organism a risk in terms of non-sterile aqueous products. Detecting BCC bacteria is also a challenge and requires validated testing methods that take into consideration the unique characteristics of different BCC strains. This webinar discusses where the organism may be found, how to detect it and what to do if it is present in the manufacturing environment ...
https://www.pharmamicroresources.com/2018/09/burkholderia-cepacia-risks-in-context.html
Molecular biology of the 2-haloacid halidohydrolase IVa from Pseudomonas cepacia MBA4 | Biochemical JournalMolecular biology of the 2-haloacid halidohydrolase IVa from Pseudomonas cepacia MBA4 | Biochemical Journal
The structural gene (hdl IVa) for the Pseudomonas cepacia MBA4 2-haloacid halidohydrolase IVa (Hdl IVa) was isolated on a 1.6 kb fragment of Ps. cepacia MBA4 chromosomal DNA. The recombinant halidohydrolase was expressed in Escherichia coli and Pseudomonas putida and the structural gene was subcloned on to the tac expression vector pBTac1. High-level expression from the tac promoter was seen to be temperature-dependent, a consequence of the nucleotide sequence adjacent to the fragment encoding the halidohydrolase. The nucleotide sequence of the fragment encoding the Hdl IVa was determined and analysed. Three ATG codons were identified in one of the open reading frames and the one corresponding to the start of the hdl IVa structural gene was determined by comparison of the predicted amino acid sequences with the experimentally determined N-terminal sequences of halidohydrolase IVa. The hdl IVa gene encoded a 231-amino acid-residue protein of M(r) 25,900. The sequence and predicted structural data ...
http://www.biochemj.org/content/284/1/87
burkholderia cepacia complex Archives - PacBioburkholderia cepacia complex Archives - PacBio
By downloading, copying, or making any use of the images located on this website (Site) you acknowledge that you have read and understand, and agree to, the terms of this Image Usage Agreement, as well as the terms provided on the Legal Notices webpage, which together govern your use of the images as provided below. If you do not agree to such terms, do not download, copy or use the images in any way, unless you have written permission signed by an authorized Pacific Biosciences representative.. Subject to the terms of this Agreement and the terms provided on the Legal Notices webpage (to the extent they do not conflict with the terms of this Agreement), you may use the images on the Site solely for (a) editorial use by press and/or industry analysts, (b) in connection with a normal, peer-reviewed, scientific publication, book or presentation, or the like. You may not alter or modify any image, in whole or in part, for any reason. You may not use any image in a manner that misrepresents the ...
https://www.pacb.com/auto_tags/burkholderia-cepacia-complex/
Microcalorimetric investigation of the effect of non-ionic surfactant by Ke Chen, Qing Zhu et al.
Polycyclic aromatic hydrocarbons (PAHs) are widespread in various ecosystems and are pollutants of great concern due to their potential toxicity, mutagenecity and carcinogenicity. Surfactant has become a hot topic for its wide application in the bioremediation of PAHs. The aim of this work is to explore a microcalorimetric method to determine the toxic effect of pyrene on Bacillus subtilis (B. subtilis) and the PAH-degrading bacteria Burkholderia cepacia (B. cepacia) and to evaluate the effect of Tween 80 on biodegradation of pyrene. Power-time curves were studied and calorimetric parameters including the growth rate constant (k), half inhibitory concentration (IC50), and total thermal effect (QT) were determined. B. subtilis, B. cepacia and B. cepacia with Tween 80 were completely inhibited when the concentration of pyrene were 200, 800 and 1600μgmL-1, respectively. B. cepacia shows better tolerance to pyrene than B. subtilis. Tween 80 significantly improves the biodegradation of pyrene by increasing
https://repository.hkbu.edu.hk/hkbu_staff_publication/1445/
Pulmonary function, serum markers of inflammation, and IgG antibodies to core lipopolysaccharide of Bhrkholderia cepacia in...
TY - JOUR. T1 - Pulmonary function, serum markers of inflammation, and IgG antibodies to core lipopolysaccharide of Bhrkholderia cepacia in adults with cystic fibrosis, following coloonization with Burkholderia cepacia. AU - Hendry, J.. AU - Nixon, L.. AU - Dodd, M.. AU - Elborn, Joseph. AU - Govan, J.. AU - Shale, D.J.. AU - Webb, A.K.. PY - 2000/1. Y1 - 2000/1. M3 - Article. VL - 29. SP - 8. EP - 10. JO - Pediatric Pulmonology. JF - Pediatric Pulmonology. SN - 8755-6863. ER - ...
https://pure.qub.ac.uk/en/publications/pulmonary-function-serum-markers-of-inflammation-and-igg-antibodi
Cystic fibrosis center coordinated care - What Doctors Want You to KnowCystic fibrosis center coordinated care - What Doctors Want You to Know
Cystic fibrosis center coordinated care - How can cystic fibrosis affect p.I.E.S development? Certainly. Cystic Fibrosis (CF) most common life-limiting genetic disorder of Caucasians, affecting approximately 30K people in the US. A, impacting mainly respiratory function. In recent years patients symptoms better controlled by genetic findings and better medications. Emotional & phys. Development depend on severity, time in hospital, complications. Morb. & mort. Factors afect emotional, cognitive behavior.
https://www.healthtap.com/topics/cystic-fibrosis-center-coordinated-care
Cook Childrens Cystic Fibrosis CenterCook Childrens Cystic Fibrosis Center
Cook Childrens Cystic Fibrosis center is nationally accredited by the Cystic Fibrosis Foundation. Our pulmonologists work to provide care for children, adolescents and adults.
https://www.cookchildrens.org/pulmonology/specialty-programs/cystic-fibrosis/Pages/default.aspx
Minnesota Cystic Fibrosis Center | MHealth.orgMinnesota Cystic Fibrosis Center | MHealth.org
The Minnesota Cystic Fibrosis Center treats children, teens and adults with cystic fibrosis and other related lung and respiratory complications
https://www.mhealth.org/childrens/care/conditions/cystic-fibrosis
The crystal structure of a triacylglycerol lipase from Pseudomonas cepacia reveals a highly open conformation in the absence of...
TY - JOUR. T1 - The crystal structure of a triacylglycerol lipase from Pseudomonas cepacia reveals a highly open conformation in the absence of a bound inhibitor. AU - Kim, Kyeong Kyu. AU - Song, Hyun Kyu. AU - Shin, Dong Hae. AU - Hwang, Kwang Yeon. AU - Sun, Se Won. PY - 1997/2/15. Y1 - 1997/2/15. N2 - Background: Lipases, a family of enzymes which catalyze the hydrolysis of triglycerides, are widely distributed in many organisms. True lipases are distinguished from esterases by the characteristic interfacial activation they exhibit at an oil-water interface. Lipases are one of the most frequently used biocatalysts for organic reactions performed under mild conditions. Their biotechnological applications include food and oil processing and the preparation of chiral intermediates for the synthesis of enantiomerically pure pharmaceuticals. Recent structural studies on several lipases have provided some clues towards understanding the mechanisms of hydrolytic activity, interfacial activation, and ...
https://koreauniv.pure.elsevier.com/en/publications/the-crystal-structure-of-a-triacylglycerol-lipase-from-pseudomona
Increased treatment requirements of patients with cystic fibrosis who harbour a highly transmissible strain of Pseudomonas...Increased treatment requirements of patients with cystic fibrosis who harbour a highly transmissible strain of Pseudomonas...
Increased treatment requirements of patients with cystic fibrosis who harbour a highly transmissible strain of Pseudomonas aeruginosa ...
https://thorax.bmj.com/content/57/11/924.citation-tools
Synthesis of 4-Amino-4-Deoxy-L-Arabinose C-Phosphonate Esters as Transferase Inhibitors | EUROCARB 2019
The group of 17 opportunistic pathogens linked to severe infections in cystic fibrosis and other immunocompromised conditions has been known as the Burkholderia cepacia complex.[1] The inner Kdo residue of Burkholderia lipopolysaccharide (LPS), which is highly conserved across the genus, is flanked by 4-amino-4-deoxy-L-arabinose units (Ara4N).[2] Furthermore, the binding of Ara4N to the phosphate groups of lipid A has been purported as one of the reasons for hindered interaction with cationic agents and consequently, to induce antibiotic resistance.[3] We set out to synthesize a series of tenable Ara4N transferase (ArnT) inhibitors with the prospect of impeding the biosynthetic pathway towards activated Ara4N species.[4] By the same token, we intend to inhibit the transfer of Ara4N residues both to Burkholderia LPS core and lipid A in vitro. Our synthetic endeavours en route to C-glycosidic derivatives mimicking either the transition state of glycosyl transfer or ArnT natural substrate will be ...
https://eurocarb2019.com/abstracts/p110
CAZy - Bacteria
Lineage: cellular organisms; Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia; Burkholderia cepacia complex; Burkholderia ...
http://www.cazy.org/b449.html
Book Englisch Für Maschinenbauer 1997
Newman LM, Wackett LP( 1995) book Englisch für Maschinenbauer and approach of war Methylene from Burkholderia cepacia G4. book Englisch für Maschinenbauer 1997 34:14066- 14076. Rehdorf J, Zimmer CL, Bornscheuer UT( 2009) Cloning, book Englisch, assimilation, and totalDownloads:2280 aldehyde of the dead oxidase from Pseudomonas putida JD1. Appl Environ Microbiol 75: 3106-3114. Appl Biochem Biotechnol 90: 187-197. Salituro FG, Demeter DA, Weintraub HJ, Lippert BJ, Resvick RJ, McDonald IA( 1994) book Englisch für und of cellular context. Haroune N, Combourieu B, Besse book, Sancelme M, Kloepfer A, et al. 2004) degradation of major by Rhodococcus anti-reverse. Appl Environ Microbiol 70: 6315-6319. Besse book Englisch für, Combourieu B, Boyse G, Sancelme M, De Wever H, et al. 2001) Long-range( 1)H-(15)N astrocyte capsaicin MolCare at other publication: a enoyl-acyl to provide music bread by two Rhodococcus cultures. Appl Environ Microbiol 67: 1412-1417. Negrete-Raymond AC, Weder B, Wackett LP( ...
http://sapernoviak.website.pl/library.php?q=book-Englisch-f%C3%BCr-Maschinenbauer-1997/
ecorn-cf: Question singleecorn-cf: Question single
The advantages of MALDI-TOF are that identification from pure culture can take minutes and is relatively cost-effective- other than the cost of the machine (approx. $200,000), relatively few reagents are required to process a sample. A recent paper investigating the use of MALDI-TOF to identify common CF pathogens, estimated that 71% of Pseudomonas aeruginosa isolates were identified by MALDI-TOF by day 2 of incubation, at which stage none had been identified by conventional culture2. Similarly, with Staphylococcus aureus, 89% were identified using MALDI-TOF by day 1 of incubation, whereas only 68% had been identified by culture on day 2. It can also identify bacteria which are slow growing much more quickly than by using standard culture techniques. In addition, it can also be used to identify yeasts and fungi, which are commonly found in CF patients. It can also determine differences between species of bacteria, such as those in the Burkholderia cepacia complex, which prove problematic for ...
http://ecorn-cf.eu/index.php?id=32&no_cache=1&L=8&tx_expertadvice_pi1%5Bshowitem%5D=3325
Marine Drugs | Free Full-Text | Antimicrobial Activity of Monoramnholipids Produced by Bacterial Strains Isolated from the Ross...Marine Drugs | Free Full-Text | Antimicrobial Activity of Monoramnholipids Produced by Bacterial Strains Isolated from the Ross...
Microorganisms living in extreme environments represent a huge reservoir of novel antimicrobial compounds and possibly of novel chemical families. Antarctica is one of the most extraordinary places on Earth and exhibits many distinctive features. Antarctic microorganisms are well known producers of valuable secondary metabolites. Specifically, several Antarctic strains have been reported to inhibit opportunistic human pathogens strains belonging to Burkholderia cepacia complex (Bcc). Herein, we applied a biodiscovery pipeline for the identification of anti-Bcc compounds. Antarctic sub-sea sediments were collected from the Ross Sea, and used to isolate 25 microorganisms, which were phylogenetically affiliated to three bacterial genera (Psychrobacter, Arthrobacter, and Pseudomonas) via sequencing and analysis of 16S rRNA genes. They were then subjected to a primary cell-based screening to determine their bioactivity against Bcc strains. Positive isolates were used to produce crude extracts from microbial
http://www.mdpi.com/1660-3397/14/5/83
U.S. FDA Investigates B. cepacian Complex Outbreak Linked to Personal CareU.S. FDA Investigates B. cepacian Complex Outbreak Linked to Personal Care
A no-rinse foam cleanser has been linked to at least 10 confirmed cases of Burkholderia cepacia complex; Shadow Holdings dba Bocchi Laboratories has voluntarily recalled the product as the FDA investigates.
https://www.cosmeticsandtoiletries.com/regulatory/region/northamerica/FDA-Investigates-B-cepacian-Complex-Outbreak-Linked-to-Personal-Care-482218091.html
Burkholderia sp. with a special note on its infection in NICU care - Review - Semantic ScholarBurkholderia sp. with a special note on its infection in NICU care - Review - Semantic Scholar
Burkholderia cepacia is a gram negative bacilli usually isolated from persons with genetic lung diseases such as Cystic fibrosis. It was discovered as a plant pathogen but later researchers have found it to be a notorious pathogen in humans. It is also a nosocomial pathogen which contaminates equipment and even disinfectants. In the other end of the spectrum, research suggests that these organisms maybe used as bio diesel and also as pesticides and fertilizers. This review of literature gives an idea of the organism and the gateway it opens for further research with a special note on the evolution of this genus as a nosocomial infection in Neonates.
https://www.semanticscholar.org/paper/Burkholderia-sp-with-a-special-note-on-its-infecti-P-Paramanantham-Klinton/763550143aec67624aea82106c483fc4185cc1bf
York Hull Adult Cystic Fibrosis Centre - Contact usYork Hull Adult Cystic Fibrosis Centre - Contact us
We are always amazed and extremely grateful when people go out of their way to raise money for cystic fibrosis services. Some people are motivated by a family member or friend living with CF, and some people have heard about the disease in the press and offer to help.. Find Out More ...
https://www.yorkhullcf.org.uk/contact-us/
Team:Costa Rica-TEC-UNA/Project - 2012.igem.orgTeam:Costa Rica-TEC-UNA/Project - 2012.igem.org
In this first phase of the project we focused our efforts to express the B. cepacia lipase in E.coli using the T7 promoter to obtain a constitutive expression of the gene. Also, we plan to conduct some experiments using the protein OmpA in order to evaluate its effect on the secretion levels of our lipase.Evaluation of the level of expression of the gene (lipase) will be done by means of RT-PCR in real time which allows us to select the best parameters for its massive production.. To evaluate, qualitatively, the bioactivity of the lipase, solid media with egg yolk were prepared. We expect to observe a degradation ring around the colonies expressing T7+lipase and T7+OmpA+lipase and a smaller or null ring around non-transformed cells. This is important since it will tell us if there are problems with the secretion of our protein and thus, evaluate if there are folding problems, problems with the signal peptide, formation of inclusion bodies or others.. ...
http://2012.igem.org/Team:Costa_Rica-TEC-UNA/Project
http://adenosine-kinase.comhttp://adenosine-kinase.com
Re preferred amongst saturated AHL molecules, whilst OCHSL and OCHSL are for carbonyl group.Similarly, for hydroxyl group OHCHSL and OHCHSL are favored.As opposed to bacteria, archaea have uncommon AHLs i.e.carboxylatedHSLs.Formation of biofilm is definitely the representative outcome of intricate Boldenone Cypionate supplier patterns of communication to enhance pathogenicity of bacteria.Within a classical instance, two bacterial species Pseudomonas aeruginosa and Burkholderia cepacia are known to reside with each other within a biofilm PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21570335 in lungs of cystic fibrosis patients reflecting intraspecies, interspecies and interkingdom networking .Likewise, multispecies biofilms formed by several bacterial species involved in chronic wounds, dental plaque, and so on.exhibit complex networking among distinct organisms.This QS based groupbehavior of microbes is termed as `sociomicrobiology .SigMol can be a extensive resource of signaling molecules ...
https://adenosine-kinase.com/2019/11/29/5181/
Contact the Cystic Fibrosis Center | Mount Sinai - New YorkContact the Cystic Fibrosis Center | Mount Sinai - New York
The CF Center entrance is located in the Bernstein Pavilion between 15th and 16th Streets, facing Second Avenue. We are easily accessible by car and by public transportation.
https://www.mountsinai.org/care/pulmonology/services/cystic-fibrosis/contact
U.S. Food and Drug Administration Approves Cayston(R) (Aztreonam for Inhalation Solution) for the Improvement of Respiratory ...U.S. Food and Drug Administration Approves Cayston(R) (Aztreonam for Inhalation Solution) for the Improvement of Respiratory ...
FOSTER CITY, Calif., Feb 22, 2010 (BUSINESS WIRE) -- Gilead Sciences, Inc. (Nasdaq:GILD) today announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Cayston(R)(aztreonam for inhalation solution) as a treatment to improve respiratory symptoms in cystic fibrosis (CF) patients with Pseudomonas aeruginosa (P. aeruginosa). Caystons safety and efficacy have not been established in pediatric patients below the age of 7, patients with forced expiratory volume in one second (FEV1) of less than 25 percent or greater than 75 percent predicted, or patients colonized with Burkholderia cepacia. Cayston is administered at a dose of 75 mg three times daily over a 28-day period and is delivered via the Altera(R) Nebulizer System, a portable, drug-specific delivery device using the eFlow(R) Technology Platform, developed by PARI Pharma GmbH. PARI Pharma also contributed to the development of Caystons drug formulation for delivery with the Altera Nebulizer System. Cayston ...
http://www.gilead.com/news/press-releases/2010/2/us-food-and-drug-administration-approves-caystonr--aztreonam-for-inhalation-solution-for-the-improvement-of-respiratory--symptoms-in-cystic-fibrosis-patients-with-pseudomonas-aeruginosa
Cystic Fibrosis Center - Rainbow Babies and Childrens Hospital - Relationship ScienceCystic Fibrosis Center - Rainbow Babies and Childrens Hospital - Relationship Science
Creating a news feed is your most valuable research tool. RelSci sends you actionable updates so you can keep tabs on the people and organizations you care about most.. ...
https://relationshipscience.com/organization/cystic-fibrosis-center-rainbow-babies-and-childrens-hospital-56026542
High thermal stability of sol-gel entrapped lipases-Cristina Paul, Paula Borza, Francisc PeterHigh thermal stability of sol-gel entrapped lipases-Cristina Paul, Paula Borza, Francisc Peter
Lipases from Burkholderia cepacia (Amano PS) and Candida antarctica B (CalB) were immobilized by sol-gel entrapment techniques, using a ternary silane precursors system with vinyl and phenyl non-hydrolyzable groups. The influence of temperature on the catalytic properties of native and immobilized lipases was investigated by incubating the biocatalysts for 24 h at temperatures between 40 C and 80 C, in n-hexane medium. A long term stability study was made with immobilized CaLB biocatalysts by incubation for 120 h in isooctane at 80 C. The acylation of aliphatic sec-alcohols by vinyl acetate was used as model reaction. Thermogravimetric analysis (TGA) was employed to evaluate the thermal stability and degradation of the immobilized biocatalysts ...
http://journal-of-agroalimentary.ro/Journal-of-Agroalimentary-Processes-and-Technologies-Article_ffe9b6.html
High thermal stability of sol-gel entrapped lipases-Cristina Paul, Paula Borza, Francisc PeterHigh thermal stability of sol-gel entrapped lipases-Cristina Paul, Paula Borza, Francisc Peter
Lipases from Burkholderia cepacia (Amano PS) and Candida antarctica B (CalB) were immobilized by sol-gel entrapment techniques, using a ternary silane precursors system with vinyl and phenyl non-hydrolyzable groups. The influence of temperature on the catalytic properties of native and immobilized lipases was investigated by incubating the biocatalysts for 24 h at temperatures between 40 C and 80 C, in n-hexane medium. A long term stability study was made with immobilized CaLB biocatalysts by incubation for 120 h in isooctane at 80 C. The acylation of aliphatic sec-alcohols by vinyl acetate was used as model reaction. Thermogravimetric analysis (TGA) was employed to evaluate the thermal stability and degradation of the immobilized biocatalysts ...
http://journal-of-agroalimentary.ro/Journal-of-Agroalimentary-Processes-and-Technologies-Article_NNMKmj.html
ICP -Instituto de Catálisis y PetroleoquímicaICP -Instituto de Catálisis y Petroleoquímica
Lipase from Burkholderia cepacia (PS) has been immobilized on Accurel MP 1000, and their performance has been compared to that of the most widely used immobilized commercial preparation of this enzyme. The maximum loading was 18 mg protein/g support, and its thermal and solvent stability was much higher than that of the commercial. PS preparations were used in hydrolysis of triacetin and methyl mandelate, in the esterification of oleic acid and ethanol and in the kinetic resolution of 1,3,4-tri-O-benzyl-myo-inositol (DL-1) using vinylacetate as activated acyl donor. For all reactions studied, PS on Accurel was more active than PS-IM. The conversion in the kinetic resolution of racemic DL-1 was optimized using response surface methodology. Optimal conditions were determined to be 2.0 mg/mL of substrate, temperature of 40oC, 2.0 ml of vinyl acetate and without water addition. Under these conditions, maximum loaded Accurel-PS preparation permitted to improve the activity in this kinetic resolution ...
http://www.icp.csic.es/buscador-publicaciones.php?tipo=Revista&id=348
Request a copy of the documentRequest a copy of the document
Enter the following information to request a copy of the document from the responsible person.. Interaction of Klebsiella oxytoca and Burkholderia cepacia in dual-species batch cultures and biofilms as a function of growth rate and substrate concentration. ...
https://scholarworks.montana.edu/xmlui/handle/1/13356/restricted-resource?bitstreamId=e38faca2-d46a-45f7-b1f8-fc2da7b2b33b
Class I Recall Issued for Contaminated IV Saline Flush Syringes - MPRClass I Recall Issued for Contaminated IV Saline Flush Syringes - MPR
Nurse Assist Inc. announced a recall of 386,175 Normal Saline Flush IV Syringes due to possible Burkholderia Cepacia contamination.
http://www.empr.com/safety-alerts-and-recalls/class-i-recall-issued-for-contaminated-iv-saline-flush-syringes/article/629638/
Nasal spray recalled due to bacterial contamination - The Clinical AdvisorNasal spray recalled due to bacterial contamination - The Clinical Advisor
Insight Pharmaceuticals, LLC, has recalled the nasal spray Nostrilla Nasal Decongestant due to potential contamination with Burkholderia cepacia, according to an FDA MedWatch safety alert.
http://www.clinicaladvisor.com/web-exclusives/nasal-spray-recalled-due-to-bacterial-contamination/article/214948/
Researchers Analyze Nasty Species of Bacteria That Has Colonized Space Stations Water DispenserResearchers Analyze Nasty Species of Bacteria That Has Colonized Space Stations Water Dispenser
To learn more about these bacteria, researchers sequenced the genomes of 24 strains collected from 2010 to 2014. All of the B. cepacia and B. contaminans strains were highly similar, and likely descended from original populations of these two bacteria that were present in the water dispenser when it left Earth.. The researchers conclude that the two bacterial species living within the dispenser are no more dangerous than similar strains that might be encountered on Earth. In the event of an infection, the bacteria can still be treated with common antibiotics.. The authors add: Within each species, the 19 B. cepacia and 5 B. contaminans recovered from the ISS were highly similar on a whole genome scale, suggesting each population may have stemmed from two distinct founding strains. The differences that can be observed among the isolates of the same species are primarily located within putative plasmids. We find that the populations of Burkholderia present in the ISS PWS are likely are not more ...
https://scitechdaily.com/researchers-analyze-nasty-species-of-bacteria-that-has-colonized-space-stations-water-dispenser/?replytocom=509485
ECFS Membership | European Cystic Fibrosis Society (ECFS)ECFS Membership | European Cystic Fibrosis Society (ECFS)
Members who are not affiliated to an academic institution and/or cystic fibrosis centre do not have voting rights although, where appropriate, may be included in the consultation process.. ...
https://www.ecfs.eu/membership
STOCK Mapt|tm1(EGFP)Klt| Tg(APPswe,PSEN1dE9)85Dbo/Mmjax CB021 mES cellsSTOCK Mapt|tm1(EGFP)Klt| Tg(APPswe,PSEN1dE9)85Dbo/Mmjax CB021 mES cells
The CB021 embryonic stem cell (ESC) line was established from a cross between a B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax (APP/PS1) hemizygous female (MMRRC#|a href=http://jaxmice.jax.org/strain/005864.html|034832-JAX|/a|) and a C57BL/6 congenic male homozygous for |em|Mapt|sup|tm1(EGFP)Klt|/sup||/em|. This cell lines may be useful in in vitro experiments directed towards differentiation of ESCs to cortical neurons expressing AD-relevant mutations.
https://www.jax.org/strain/025777
Vínculos - Stabilis 4.0Vínculos - Stabilis 4.0
The SDSD is a database of the visual appearance of drug combinations reported in palliativedrugs.com prospective international multicentre surveys and also from individual reporting. There are currently over 2350 entries.This data is categorised as observational data, and a description of appeared compatible has been assigned if there was no obvious physical change in appearance of the combination in use, e.g. discoloration, clouding, or the precipitation of particles/crystals ...
https://www.stabilis.org/InfostabLien.php?liste=1&sortBy=titre&sortOrder=ASC&codeLangue=SP-sp
Vietnam Detects New Highly Transmissible Coronavirus Variant - NPR | 511Host Global Network News
https://www.npr.org/sections/coronavirus-live-updates/2021/05/29/1001590855/vietnam-detects-new-highly-transmissible-coronavirus-variant
https://511host.com/2021/05/29/vietnam-detects-new-highly-transmissible-coronavirus-variant-npr/
Covid-19 Update: Companies Affected by the Delta Variant - Zerg WatchCovid-19 Update: Companies Affected by the Delta Variant - Zerg Watch
The WHO declared the Delta strain as a variant of concern, and the CDC posted a new guideline after many vaccinated people got infected with the Delta variant. The study that the CDC revealed last month showed that both vaccinated and unvaccinated people produce similar amounts of virus when infected with the strain that originated in India.. The high viral load was responsible for an outbreak in Massachusetts, where 469 vaccinated people got infected after attending crowded events.The highly transmissible strain has also affected many businesses, especially in the entertainment and hospitality industries. A recent article mentions several notorious companies struggling to survive the pandemic. ...
https://zergwatch.com/covid-19-update-companies-affected-by-the-delta-variant/9781/
Make Way Environmental Ontario | Installation Septique System O | DBO ExpertMake Way Environmental Ontario | Installation Septique System O | DBO Expert
Expert en Installation Septique Ontario. Contactez-le. Un choix dinstallation septique économique, écologique et durable pour votre fosse septique.
https://dboexpert.com/store/make-way-environmental-septic-system-expert-ontario/
Biblio Search | sciensano.beBiblio Search | sciensano.be
C en 2002. Depuis 2008, le nombre de cas confirmés par le CNR sest stabilisé autour dune centaine de cas/an, soit 96 cas en 2017 et une incidence estimée à 0,85 cas confirmés/100.000 habitants. En 2017, le .... ...
https://www.sciensano.be/en/search/biblio/incidence/biblio_type/Sci%252E%20report%2C%20recommendat%C2%B0%2C%20guidance%20doc%252E%2C%20directive%2C%20monograph
Burkholderia cepacia complexBurkholderia cepacia complex
Burkholderia cepacia is also found in marine environment (marine sponge) and some strain of Burkholderia cepacia can tolerate ... Burkholderia cepacia complex in the NCBI Taxonomy Browser Type strain of Burkholderia cepacia complex at BacDive, the Bacterial ... Burkholderia cepacia complex (BCC), or simply Burkholderia cepacia, is a group of catalase-producing, lactose-nonfermenting, ... Burkholderia cepacia is intrinsically resistant to colistin and usually resistant to aminoglycosides. In people with cystic ...
https://en.wikipedia.org/wiki/Burkholderia_cepacia_complex
OrnibactinOrnibactin
"Ornibactin production and transport properties in strains of Burkholderia vietnamiensis and Burkholderia cepacia (formerly ... Coenye T, Vandamme P, Govan JR, LiPuma JJ (October 2001). "Taxonomy and identification of the Burkholderia cepacia complex". ... LiPuma JJ (September 1998). "Burkholderia cepacia. Management issues and new insights". Clinics in Chest Medicine. 19 (3): 473- ... Speert DP (September 2002). "Advances in Burkholderia cepacia complex". Paediatric Respiratory Reviews. 3 (3): 230-5. doi: ...
https://en.wikipedia.org/wiki/Ornibactin
Chronic granulomatous diseaseChronic granulomatous disease
Pseudomonas cepacia, a.k.a. Burkholderia cepacia. Nocardia. Fungi Aspergillus species. Aspergillus has a propensity to cause ... "Chronic granulomatous disease presenting in childhood with Pseudomonas cepacia septicaemia". The Journal of Infection. 27 (3): ...
https://en.wikipedia.org/wiki/Chronic_granulomatous_disease
Walter H. BurkholderWalter H. Burkholder
Burkholderia cepacia:Friend or Foe? - Jennifer L. Parke Annual Review of Microbiology Annual Review of Phytopathology Some ... Bacterial strains from the Burkholderia cepacia complex (Bcc) are opportunistic pathogens in humans with cystic fibrosis and ... In 1950 he first described the bacteria, Pseudomonas cepacia, later Burkholderia spp., responsible for causing sour skin ...
https://en.wikipedia.org/wiki/Walter_H._Burkholder
GenomovarGenomovar
"Burkholderia cepacia and cystic fibrosis". Archived from the original on 2008-09-16. Retrieved 2008-08-15. (Classical genetics) ... Genomovar is a term commonly used within the genera Burkholderia and Agrobacterium to denote strains which are phylogenetically ...
https://en.wikipedia.org/wiki/Genomovar
Burkholderia cenocepaciaBurkholderia cenocepacia
... is one of over twenty bacteria in the Burkholderia cepacia complex (Bcc), and among these species, it ... Within the Burkholderia genus, the Burkholderia cepacia complex contains over 20 related species that cause opportunistic ... is Burkholderia cenocepacia, a member of a bacterial group collectively referred to as the Burkholderia cepacia complex." ... Burkholderia cepacia was originally defined as a single species, but it is now one of several species in the Bcc. Although ...
https://en.wikipedia.org/wiki/Burkholderia_cenocepacia
Burkholderia metallicaBurkholderia metallica
nov., Burkholderia seminalis sp. nov. and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia ... "Burkholderia metallica". Peter Vandamme. "Identification of Burkholderia cepacia complex bacteria" (PDF). Archived from the ... "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. ... Burkholderia metallica is a bacterium from the genus of Burkholderia and the family of Burkholderiaceae which belongs to the ...
https://en.wikipedia.org/wiki/Burkholderia_metallica
Burkholderia contaminansBurkholderia contaminans
... bacterium from the genus of Burkholderia and the family of Burkholderiaceae and belongs to the Burkholderia cepacia complex, ... Rose, H.; Baldwin, A.; Dowson, C. G.; Mahenthiralingam, E. (2009). "Biocide susceptibility of the Burkholderia cepacia complex ... Burkholderia acidipaludis can cause biliary sepsis. "Genus Burkholderia". List of Prokaryotic Names with Standing in ... Type strain of Burkholderia contaminans at BacDive - the Bacterial Diversity Metadatabase v t e (Articles with short ...
https://en.wikipedia.org/wiki/Burkholderia_contaminans
Povidone-iodinePovidone-iodine
The non-sterile form of Povidone iodine has a long history of intrinsic contamination with Burkholderia cepacia (aka ... Rose H, Baldwin A, Dowson CG, Mahenthiralingam E (March 2009). "Biocide susceptibility of the Burkholderia cepacia complex". ... Pseudomonas cepacia), and other opportunistic pathogens. Its ability to harbor such microbes further underscores the importance ...
https://en.wikipedia.org/wiki/Povidone-iodine
Burkholderia arborisBurkholderia arboris
nov., Burkholderia seminalis sp. nov. and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia ... "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. ... B. arboris belongs to the Burkholderia cepacia complex. "J.P. Euzéby: List of bacterial names with standing in nomenclature". " ... Burkholderia arboris is a Gram-negative, aerobic, non-spore-forming bacterium of the genus Burkholderia and the family ...
https://en.wikipedia.org/wiki/Burkholderia_arboris
Burkholderia territoriiBurkholderia territorii
"Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from ... Burkholderia territorii is a bacterium from the genus of Burkholderia. Burkholderia territorii belongs to the Burkholderia ... "Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from ... Type strain of Burkholderia territorii at BacDive - the Bacterial Diversity Metadatabase De Smet, B; Mayo, M; Peeters, C; ...
https://en.wikipedia.org/wiki/Burkholderia_territorii
Burkholderia pseudomultivoransBurkholderia pseudomultivorans
... belongs to the Burkholderia cepacia complex. LSPN lpsn.dsmz.de Straininfo of Burkholderia ... Burkholderia pseudomultivorans is a bacterium from the genus Burkholderia and the family Burkholderiaceae which was isolated ... UniProt Type strain of Burkholderia pseudomultivorans at BacDive - the Bacterial Diversity Metadatabase v t e (Articles with ... pseudomultivorans Srinivasan, S; Kim, J; Kang, S. R.; Jheong, W. H.; Lee, S. S. (2013). "Burkholderia humi sp. nov., isolated ...
https://en.wikipedia.org/wiki/Burkholderia_pseudomultivorans
Burkholderia seminalisBurkholderia seminalis
nov., Burkholderia seminalis sp. nov. and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia ... bacterium from the genus Burkholderia and the family Burkholderiaceae which belongs to the Burkholderia cepacia complex. " ... "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. ... "Burkholderia seminalis DSM 23518". UniProt. Retrieved 2 October 2015. Type strain of Burkholderia seminalis at BacDive - the ...
https://en.wikipedia.org/wiki/Burkholderia_seminalis
Burkholderia latensBurkholderia latens
nov., Burkholderia seminalis sp. nov. and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia ... nov., Burkholderia seminalis sp. nov. and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia ... Colonies of Burkholderia latens are moist. A.C. Parte. "Burkholderia". LPSN. Retrieved 2014-03-22. "Burkholderia latens Taxon ... "Burkholderia latens". uniprot.org. Retrieved 2014-03-22. "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., ...
https://en.wikipedia.org/wiki/Burkholderia_latens
Burkholderia diffusaBurkholderia diffusa
nov., Burkholderia seminalis sp. nov. and Burkholderia metallica sp. nov., novel species within the Burkholderia cepacia ... "Burkholderia latens sp. nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. ... Burkholderia diffusa is a gram-negative, aerobic, non-spore-forming bacterium from the genus of Burkholderia and the family of ... "hisA - ProFAR isomerase - Burkholderia diffusa - hisA gene & protein". Type strain of Burkholderia diffusa at BacDive - the ...
https://en.wikipedia.org/wiki/Burkholderia_diffusa
Burkholderia stagnalisBurkholderia stagnalis
"Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from ... Burkholderia stagnalis is a bacterium from the genus of Burkholderia. Burkholderia stagnalis belongs to the Burkholderia ... "Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from ... Type strain of Burkholderia stagnalis at BacDive - the Bacterial Diversity Metadatabase De Smet, B; Mayo, M; Peeters, C; ...
https://en.wikipedia.org/wiki/Burkholderia_stagnalis
Cystic fibrosisCystic fibrosis
Lord R, Jones AM, Horsley A (April 2020). "Antibiotic treatment for Burkholderia cepacia complex in people with cystic fibrosis ... Eventually, Pseudomonas aeruginosa (and sometimes Burkholderia cepacia) dominates. By 18 years of age, 80% of patients with ... Burkholderia) cepacia and multiresistant Pseudomonas aeruginosa". The Netherlands Journal of Medicine. 46 (6): 280-7. doi: ... opportunistic infection due to Burkholderia cepacia complex can occur, especially through transmission from patient to patient ...
https://en.wikipedia.org/wiki/Cystic_fibrosis
OsteomyelitisOsteomyelitis
Weinstein, Lenny; Knowlton, Christin A.; Smith, Miriam A. (2007-12-16). "Cervical osteomyelitis caused by Burkholderia cepacia ... The Burkholderia cepacia complex has been implicated in vertebral osteomyelitis in intravenous drug users. In general, ...
https://en.wikipedia.org/wiki/Osteomyelitis
PseudomonasPseudomonas
... with the type species Burkholderia cepacia (Palleroni and Holmes 1981) comb. Nov". Microbiology and Immunology. 36 (12): 1251- ... "Characterization of PCR-ribotyping for Burkholderia (Pseudomonas) cepacia". Journal of Clinical Microbiology. 32 (10): 2422- ... Yabuuchi, E.; Kosako, Y.; Yano, I.; Hotta, H.; Nishiuchi, Y. (1995). "Transfer of two Burkholderia and an Alcaligenes species ... Other strains previously classified in the genus Pseudomonas are now classified in the genera Burkholderia and Ralstonia. In ...
https://en.wikipedia.org/wiki/Pseudomonas
Burkholderia dolosaBurkholderia dolosa
... is a species of bacteria. It is a member of the Burkholderia cepacia complex. This particular strain is ... cite web}}: Missing or empty ,title= (help) "Burkholderia dolosa". NCBI Taxonomy Browser. 152500. Type strain of Burkholderia ...
https://en.wikipedia.org/wiki/Burkholderia_dolosa
CefotaximeCefotaxime
Burkholderia cepacia Proteus mirabilis and P. vulgaris Enterobacter spp. Bacteroides spp. Fusobacterium spp. Notable organisms ...
https://en.wikipedia.org/wiki/Cefotaxime
Abdominal obesityAbdominal obesity
LiPuma JJ, Spilker T, Coenye T, Gonzalez CF (June 2002). "An epidemic Burkholderia cepacia complex strain identified in soil". ...
https://en.wikipedia.org/wiki/Abdominal_obesity
ColistinColistin
Brucella Burkholderia cepacia Chryseobacterium indologenes Edwardsiella Elizabethkingia meningoseptica Francisella tularensis ...
https://en.wikipedia.org/wiki/Colistin
List of Nepenthes endophyte speciesList of Nepenthes endophyte species
Burkholderia cepacia strain AIMST Ngse1 16S ribosomal RNA gene, partial sequence. NCBI. Burkholderia multivorans strain AIMST ... Burkholderiaceae Burkholderia Burkholderia cepacia strain AIMST Ngse1 (N. gracilis; Selangor, Malaysia; leaf tissue) ... Burkholderia multivorans strain AIMST Ngse2 (N. gracilis; Selangor, Malaysia; leaf tissue) Enterobacteriaceae Citrobacter ...
https://en.wikipedia.org/wiki/List_of_Nepenthes_endophyte_species
Keratin 13Keratin 13
Sajjan US, Sylvester FA, Forstner JF (2000). "Cable-Piliated Burkholderia cepacia Binds to Cytokeratin 13 of Epithelial Cells ...
https://en.wikipedia.org/wiki/Keratin_13
Burkholderia pseudomalleiBurkholderia pseudomallei
Burkholderia cepacia medium, and Burkholderia pseudomallei selective agar for clinical isolation of Burkholderia pseudomallei ... Pathema Burkholderia resource "Burkholderia pseudomallei". NCBI Taxonomy Browser. 28450. (Articles with short description, ... 2011). "Rapid identification of Burkholderia pseudomallei and Burkholderia mallei by fluorescence in situ hybridization (FISH) ... or Burkholderia cepacia medium) may be used for selective isolation. Cultures typically become positive in 24 to 48 hours (this ...
https://en.wikipedia.org/wiki/Burkholderia_pseudomallei
2-hydroxy-1,4-benzoquinone reductase2-hydroxy-1,4-benzoquinone reductase
"Novel pathway for conversion of chlorohydroxyquinol to maleylacetate in Burkholderia cepacia AC1100". Journal of Bacteriology. ...
https://en.wikipedia.org/wiki/2-hydroxy-1,4-benzoquinone_reductase
Claire WainwrightClaire Wainwright
"Factors Influencing Acquisition of Burkholderia Cepacia Complex Organisms in Patients with Cystric Fibrosis". Journal of ...
https://en.wikipedia.org/wiki/Claire_Wainwright
Burkholderia pyrrociniaBurkholderia pyrrocinia
"Burkholderia anthina sp. nov. and Burkholderia pyrrocinia, two additional Burkholderia cepacia complex bacteria, may confound ... "Polyphasic Characterisation of Burkholderia cepacia-Like Isolates Leading to the Emended Description of Burkholderia pyrrocinia ... "Burkholderia pyrrocinia". NCBI Taxonomy Browser. 60550. "Genus Burkholderia". List of Prokaryotic Names with Standing in ... Burkholderia pyrrocinia is a Gram-negative bacterium which has been found in soil as well as in the sputum of patients with ...
https://en.wikipedia.org/wiki/Burkholderia_pyrrocinia
Lung microbiotaLung microbiota
Pseudomonas aeruginosa, Staphylococcus aureus, and Burkholderia cepacia are found most often in cystic fibrosis patients. High- ...
https://en.wikipedia.org/wiki/Lung_microbiota
Contamination controlContamination control
Seven of the most common contaminants are: Aspergillus niger Burkholderia cepacia Clostridium difficile Escherichia coli ...
https://en.wikipedia.org/wiki/Contamination_control
BCCBCC
... a defunct industry standards organization Burkholderia cepacia complex, a bacterial pathogen Business Controls Corporation, ...
https://en.wikipedia.org/wiki/BCC
2010 Johnson & Johnson childrens product recall2010 Johnson & Johnson children's product recall
Burkholderia cepacia bacteria was found on some equipment which, according to Johnson & Johnson, never was actually put into ...
https://en.wikipedia.org/wiki/2010_Johnson_&_Johnson_children's_product_recall
Ashdowns mediumAshdown's medium
Burkholderia cepacia medium, and Burkholderia pseudomallei selective agar for clinical isolation of Burkholderia pseudomallei ... Ashdown's medium is a selective culture medium for the isolation and characterisation of Burkholderia pseudomallei (the ... 2007). "Biological relevance of colony morphology and phenotypic switching by Burkholderia pseudomallei". J Bacteriol. 189 (3 ...
https://en.wikipedia.org/wiki/Ashdown's_medium
Elaeis guineensisElaeis guineensis
Two bacterial isolates, Burkholderia cepacia (B3) and Pseudomonas aeruginosa (P3) were selected for evaluation in the ...
https://en.wikipedia.org/wiki/Elaeis_guineensis
FAD reductase (NADH)FAD reductase (NADH)
... of Burkholderia cepacia AC1100". Journal of Bacteriology. 185 (9): 2786-92. doi:10.1128/jb.185.9.2786-2792.2003. PMC 154418. ... H+ The enzyme from Burkholderia phenoliruptrix has a preference for FAD. Gisi MR, Xun L (May 2003). "Characterization of ...
https://en.wikipedia.org/wiki/FAD_reductase_(NADH)
HypothiocyaniteHypothiocyanite
Aeromonas hydrophila Bacillus brevis Bacillus cereus Bacillus megaterium Bacillus subtilis Burkholderia cepacia Campylobacter ...
https://en.wikipedia.org/wiki/Hypothiocyanite
Microbial symbiosis and immunityMicrobial symbiosis and immunity
"Influence of Pseudomonas aeruginosa Exoproducts on Virulence Factor Production in Burkholderia cepacia: Evidence of ...
https://en.wikipedia.org/wiki/Microbial_symbiosis_and_immunity
Interspecies communicationInterspecies communication
"Influence of Pseudomonas aeruginosa Exoproducts on Virulence Factor Production in Burkholderia cepacia: Evidence of ... P. aeruginosa exoproducts help B. cepacia to attach to different surfaces. The New Scientist: Lab chimp speaks his own language ...
https://en.wikipedia.org/wiki/Interspecies_communication
Secondary chromosomeSecondary chromosome
Burkholderia cepacia complex in 1994, Rhizobium meliloti in 1995, Bacillus thuringiensis in 1996, and now about 10% of ... Cheng, H P; Lessie, T G (1994). "Multiple replicons constituting the genome of Pseudomonas cepacia 17616". Journal of ... "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility". Proceedings of the National ... One of the largest chromids is the one in Burkholderia pseudomallei, which exceeds 3.1 million nucleotides in size, i.e. 3.1 ...
https://en.wikipedia.org/wiki/Secondary_chromosome
Burkholderia anthinaBurkholderia anthina
"Burkholderia anthina sp. nov. and Burkholderia pyrrocinia, two additional Burkholderia cepacia complex bacteria, may confound ... Burkholderia J.P. Euzéby: List of Prokaryotic names with Standing in Nomenclature "Burkholderia anthina". NCBI Taxonomy Browser ... Type strain of Burkholderia anthina at BacDive - the Bacterial Diversity Metadatabase v t e (Articles with short description, ... Burkholderia anthina is a species of bacteria of the family Burkholderiaceae. Vandamme, Peter; Henry, Deborah; Coenye, Tom; ...
https://en.wikipedia.org/wiki/Burkholderia_anthina
CatalaseCatalase
Other catalase-positive organisms include Listeria, Corynebacterium diphtheriae, Burkholderia cepacia, Nocardia, the family ... cepacia and H. pylori. Acatalasia is a condition caused by homozygous mutations in CAT, resulting in a lack of catalase. ...
https://en.wikipedia.org/wiki/Catalase
BetaproteobacteriaBetaproteobacteria
Burkholderia cepacia which causes bulb rot in onions as well as Xylophilus ampelinus which causes necrosis of grapevines. ...
https://en.wikipedia.org/wiki/Betaproteobacteria
BurkholderiaBurkholderia
... ambifaria Burkholderia anthina Burkholderia arboris Burkholderia cenocepacia Burkholderia cepacia Burkholderia ... Burkholderia dolosa Burkholderia gladioli Burkholderia glumae Burkholderia humptydooensis Burkholderia lata Burkholderia latens ... Burkholderia mallei Burkholderia metallica Burkholderia multivorans Burkholderia oklahomensis Burkholderia plantarii ... Burkholderia pseudomallei Burkholderia pseudomultivorans Burkholderia puraquae Burkholderia pyrrocinia Burkholderia seminalis ...
https://en.wikipedia.org/wiki/Burkholderia
Rieske proteinRieske protein
X-ray structure of Rieske-type ferredoxin associated with biphenyl dioxygenase from Burkholderia cepacia PDB: 1G8J​ - X-ray ...
https://en.wikipedia.org/wiki/Rieske_protein
Elizabethkingia meningosepticaElizabethkingia meningoseptica
... but resembles Burkholderia cepacia, which is also a nonfermenter and does not grow well on MacConkey agar. These two can be ... distinguished by the indole test or the Pyr test, both of which should be clearly negative for B. cepacia and positive for E. ...
https://en.wikipedia.org/wiki/Elizabethkingia_meningoseptica
Burkholderia cepacia in Healthcare Settings | HAI | CDCBurkholderia cepacia in Healthcare Settings | HAI | CDC
General Information about B. cepacia. Burkholderia cepacia [burk-hōld-er-ee-uh si-pay-shee-uh] (also called B. cepacia) is the ... B cepacia is a known cause of infections in hospitalized patients.. Symptoms of B. cepacia infection. The effects of B. cepacia ... B. cepacia bacteria are often resistant to common antibiotics.. Populations susceptible to B. cepacia infection. B. cepacia ... Exposure to B. cepacia in the environment.. Treatment of B. cepacia infection. B. cepacia can be resistant to many common ...
https://www.cdc.gov/hai/organisms/bcepacia.html
Burkholderia cepacia Medication: Antibiotics, Cefiderocol, Ceftazidime-AvibactamBurkholderia cepacia Medication: Antibiotics, Cefiderocol, Ceftazidime-Avibactam
B cepacia is an organism of low virulence and is a frequent colonizer of fluids used in the hospital (eg, irrigation solutions ... Burkholderia cepacia is an aerobic gram-negative bacillus found in various aquatic environments. ... encoded search term (Burkholderia cepacia) and Burkholderia cepacia What to Read Next on Medscape ... Burkholderia cepacia Medication. Updated: Mar 15, 2023 * Author: Sara Ahmed, MBBS, MRCP(UK), FCPS; Chief Editor: Michael Stuart ...
https://emedicine.medscape.com/article/237122-medication
Burkholderia cepacia
... Description. Burkholderia cepacia complex P/A Culture. EMSL Test Code: M713. Burkholderia cepacia complex ... Burkholderia cepacia. Burkholderia cepacia. Category. Microbiology Laboratory. Test. ...
https://www.emsl.com/Services.aspx?action=show&TopServiceCategoryID=5&serviceid=1681
Environmental Burkholderia cepacia Complex Isolates from Human Infections - Volume 13, Number 3-March 2007 - Emerging...
Cunha MV, Leitao JH, Mahenthiralingam E, Vandamme P, Lito L, Barreto C, Molecular analysis of Burkholderia cepacia complex ... An epidemic Burkholderia cepacia complex strain identified in soil.Lancet. 2002;359:2002-3. DOIPubMedGoogle Scholar ... Agricultural use of Burkholderia (Pseudomonas) cepacia: a threat to human health?Emerg Infect Dis. 1998;4:221-7.PubMedGoogle ... Taxonomy and identification of the Burkholderia cepacia complex.J Clin Microbiol. 2001;39:3427-36. DOIPubMedGoogle Scholar ...
https://wwwnc.cdc.gov/eid/article/13/3/06-0403_article
Case Report: Community-Acquired Burkholderia cepacia Pneumonia of a Patient with Pulmonary Tuberculosis in: The American...Case Report: Community-Acquired Burkholderia cepacia Pneumonia of a Patient with Pulmonary Tuberculosis in: The American...
We report a 29-year-old female who suffered pulmonary tuberculosis and developed community-acquired Burkholderia cepacia ... Burkholderia cepacia complex in cystic fibrosis in a Brazilian reference center. Med Microbiol Immunol (Berl) 206: 447-461. ... Community-acquired Burkholderia cepacia pneumonia: a report of two immunocompetent patients. Tuberk Toraks 59: 380-383. ... Classification and identification of the Burkholderia cepacia complex: past, present and future. Syst Appl Microbiol 34: 87-95. ...
https://www.ajtmh.org/abstract/journals/tpmd/107/1/article-p86.xml?rskey=G1yUWE&result=1
An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and...An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and...
Burkholderia dolosa is a member of the Burkholderia cepacia complex (BCC), which is a group of bacteria that cause chronic lung ... An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and ... "An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and ...
https://dash.harvard.edu/handle/1/30371001
Potential of the Burkholderia cepacia Complex to Produce 4-Hydroxy-3-Methyl-2-Alkyquinolines - EspaceINRSPotential of the Burkholderia cepacia Complex to Produce 4-Hydroxy-3-Methyl-2-Alkyquinolines - EspaceINRS
... especially Burkholderia pseudomallei, Burkholderia thailandensis, Burkholderia ambifaria, and Burkholderia cepacia, are known ... Potential of the Burkholderia cepacia Complex to Produce 4-Hydroxy-3-Methyl-2-Alkyquinolines ... in the Burkholderia cepacia complex (Bcc) group. Based on the available sequence data, about one third of Bcc species carry a ... Potential of the Burkholderia cepacia Complex to Produce 4-Hydroxy-3-Methyl-2-Alkyquinolines Frontiers in Cellular and ...
https://espace.inrs.ca/id/eprint/8198/
Burkholderia cepacia Clinical Presentation: History, Physical, CausesBurkholderia cepacia Clinical Presentation: History, Physical, Causes
B cepacia is an organism of low virulence and is a frequent colonizer of fluids used in the hospital (eg, irrigation solutions ... Burkholderia cepacia is an aerobic gram-negative bacillus found in various aquatic environments. ... encoded search term (Burkholderia cepacia) and Burkholderia cepacia What to Read Next on Medscape ... Burkholderia cepacia Clinical Presentation. Updated: Mar 15, 2023 * Author: Sara Ahmed, MBBS, MRCP(UK), FCPS; Chief Editor: ...
https://emedicine.staging.medscape.com/article/237122-clinical
Burkholderia Cepacia Contamination LawsuitBurkholderia Cepacia Contamination Lawsuit
If you or a loved one have been sickened by Burkholderia Cepacia, chances are that a drug that you used is to blame. When that ... Serious Recent Burkholderia Cepacia Outbreaks. Some serious outbreaks of Burkholderia Cepacia infections include:. *In 2016, ... Burkholderia Cepacia Contamination Lawsuit. Contact Us Today for a Free Case Review ... If you or a loved one have been sickened by Burkholderia Cepacia, chances are that a drug that you used is to blame. When that ...
https://www.gedlawyers.com/practice-areas/product-liability/weed-killer/
Atypical presentation of chronic granulomatous disease with Burkholderia cepacia<...
Vining M, Sharma N, Guill M. Atypical presentation of chronic granulomatous disease with Burkholderia cepacia. BMJ Case Reports ... Burkholderia cepacia, a catalase-producing organism, is known to infect patients with dysfunctional immune systems. We report a ... Burkholderia cepacia, a catalase-producing organism, is known to infect patients with dysfunctional immune systems. We report a ... Burkholderia cepacia, a catalase-producing organism, is known to infect patients with dysfunctional immune systems. We report a ...
https://augusta.pure.elsevier.com/en/publications/atypical-presentation-of-chronic-granulomatous-disease-with-burkh
Carbon Isotope Fractionation during Aerobic Biodegradation of Trichloroethene by |i|Burkholderia cepacia|/i| ...
Carbon Isotope Fractionation during Aerobic Biodegradation of Trichloroethene by Burkholderia cepacia G4: a Tool To Map ...
https://experts.mcmaster.ca/display/publication197018
COCA Clinical Reminder: August 12, 2016 | CDC Emergency Preparedness & ResponseCOCA Clinical Reminder: August 12, 2016 | CDC Emergency Preparedness & Response
The agency confirmed the product had been contaminated with Burkholderia cepacia, a bacteria linked to an outbreak in five ... Multistate Outbreak of Burkholderia cepacia Infections. On July 16, 2016, FDA alerted healthcare professionals that PharmaTech ... due to possible Burkholderia cepacia contamination.. Actions Healthcare Professionals Should Take. Consumers, pharmacies, and ... recall of all liquid products manufactured by PharmaTech and distributed by 6 companies due to possible Burkholderia cepacia ...
https://emergency.cdc.gov/coca/reminders/2016/2016august12.asp
IMSEAR at SEARO: Burkholderia cepacia complex: Beyond pseudomonas and acinetobacter.
The International Burkholderia cepacia Working Group is open to clinicians and scientists interested in advancing knowledge of ... Burkholderia cepacia complex (BCC) is an important nosocomial pathogen in hospitalised patients, particularly those with prior ... Gautam V, Singhal L, Ray P. Burkholderia cepacia complex: Beyond pseudomonas and acinetobacter. Indian Journal of Medical ...
https://imsear.searo.who.int/handle/123456789/143767?mode=full
BURKHOLDERIA CEPACIA SELECTIVE AGAR BASE - TMMediaBURKHOLDERIA CEPACIA SELECTIVE AGAR BASE - TMMedia
Burkholderia cepacia species are gram negative, rod shaped bacteria. The organism may lead to Burkholderia cepacia syndrome, a ... This medium was found to be superior to MacConkey Agar for growth of B. cepacia. Burkholderia cepacia have the potential of ... for isolation of Burkholderia cepacia from the respiratory secretions of patients with cystic fibrosis and other non-clinical ... Burkholderia cepacia is an important opportunistic pathogen and causes pulmonary infection among individuals with cystic ...
https://www.tmmedia.in/product/burkholderia-cepacia-selective-agar-base/
Welcome - The International Burkholderia cepacia Working Group
The International Burkholderia cepacia Working Group Fostering research in Burkholderia cepacia complex ... Welcome to the new website of the International Burkholderia cepacia Working Group. This sites goal is to foster sharing of ... information and resources relevant to Burkholderia cepacia complex researchers. If you are a researcher working with B. cepacia ...
https://ibcwg.org/index.php/home/
pdtaR protein (Burkholderia cepacia) - STRING interaction networkpdtaR protein (Burkholderia cepacia) - STRING interaction network
Burkholderia cepacia. NCBI taxonomy Id: 292. Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691 ... Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717 ...
https://string-db.org/network/292.DM42_6267
Burkholderia cepacia complex genomovars and pulmonary transplantation outcomes in patients with cystic fibrosis - ePrints -...Burkholderia cepacia complex genomovars and pulmonary transplantation outcomes in patients with cystic fibrosis - ePrints -...
Burkholderia cepacia is a group of organisms that comprises seven genotypically distinct species (B cepacia genomovars I-VII), ... Burkholderia cepacia complex genomovars and pulmonary transplantation outcomes in patients with cystic fibrosis. Lookup NU ... which are collectively known as the B cepacia complex. Preoperative infection with B cepacia Is associated with a poor ... We studied archived isolates with PCR-based methods, and recorded excessive mortality in patients infected with B cepacia ...
https://eprints.ncl.ac.uk/128572
USP Test for Burkholderia cepacia Complex | Microchem LaboratoryUSP Test for Burkholderia cepacia Complex | Microchem Laboratory
The USP ,60, Test for Burkholderia cepacia Compl ... Test ... The USP ,60, Test for Burkholderia cepacia Complex, like the ... USP ,60, tests are necessary for cosmetic and personal products to determine the absence of Burkholderia cepacia Complex. ... specifically those in the Burkholderia cepacia Complex, a complex comprised of 20+ species of strong water-borne opportunistic ... then streaking the enriched sample onto selective media for determination of the presence or absence of Burkholderia cepacia ...
https://microchemlab.com/test/usp-test-for-burkholderia-cepacia-complex/
Drosophila melanogaster as a model host for the Burkholderia cepacia complex. - RIIP - Réseau International des Instituts...Drosophila melanogaster as a model host for the Burkholderia cepacia complex. - RIIP - Réseau International des Instituts...
Drosophila melanogaster as a model host for the Burkholderia cepacia complex. Josée Castonguay-Vanier 1 Ludovic Vial 1 Julien ... Drosophila melanogaster as a model host for the Burkholderia cepacia complex.. PLoS ONE, 2010, 5 (7), pp.e11467. ⟨10.1371/ ...
https://hal-riip.archives-ouvertes.fr/pasteur-00547901
Evaluating the alginate oligosaccharide (OligoG) as a therapy for Burkholderia cepacia complex cystic fibrosis lung infection ...Evaluating the alginate oligosaccharide (OligoG) as a therapy for Burkholderia cepacia complex cystic fibrosis lung infection ...
... Evaluating the alginate oligosaccharide (OligoG) as a therapy for Burkholderia cepacia complex cystic fibrosis lung infection. ... OligoG has previously shown potentiation of aztreonam against Burkholderia cepacia complex (Bcc) through biofilm disruption. A ...
https://orca.cardiff.ac.uk/id/eprint/151498/
Lung Transplantation: Practice Essentials, Background, IndicationsLung Transplantation: Practice Essentials, Background, Indications
Lung transplantation can be considered in patients infected with Burkholderia cenocepacia, Burkholderia gladioli, and multi- ... Some centers do not offer transplants to patients infected with B cepacia. Also, patients who have active tuberculosis ... Snell GI, de Hoyos A, Krajden M. Pseudomonas cepacia in lung transplant recipients with cystic fibrosis. Chest. 1993 Feb. 103(2 ... In patients with cystic fibrosis, infection with B cepacia is associated with significant mortality rates because this organism ...
https://www.medscape.com/answers/429499-188649/what-are-the-ishlt-criteria-for-referral-and-listing-for-lung-transplantation-in-patients-with-pulmonary-arterial-hypertension
Cicero and Burkholderia cepacia: What's in a Name? - Volume 9, Number 4-April 2003 - Emerging Infectious Diseases journal - CDC
Taxonomy and identification of the Burkholderia cepacia complex. J Clin Microbiol. 2001;39:3427-36. DOIPubMedGoogle Scholar ... Moore, J. E., & Williams, F. (2003). Cicero and Burkholderia cepacia: Whats in a Name?. Emerging Infectious Diseases, 9(4), ... Moore JE, Williams F. Cicero and Burkholderia cepacia: Whats in a Name?. Emerging Infectious Diseases. 2003;9(4):506-507. doi: ... Burkholderia cepacia, an important gram-negative bacterial pathogen in patients with cystic fibrosis, may cause premature death ...
https://wwwnc-origin.cdc.gov/eid/article/9/4/AD-0904
Efficacy of soil-borne Burkholderia Cepacia-like MB-01 strain for shobicron and vertimec degradationEfficacy of soil-borne Burkholderia Cepacia-like MB-01 strain for shobicron and vertimec degradation
Antibiotic resistance in Burkholderia cepacia at two regional cystic fibrosis centres in Northern Ireland: is there a need for ... As a result, a novel theory about the use of Burkholderia Cepacia-Like MB-01 to clean up pesticide-contaminated soil can ... Shobicron and vertimec degrading efficiency of Burkholderia Cepacia-like MB-01. The strain MB-01 was cultivated on shobicron ... As a result, Burkholderia Cepacia-Like MB-01 should be evaluated with industrial waste and in natural habitats in future ...
https://www.bsmiab.org/jabet/178-1652146042-efficacy-of-soil-borne-burkholderia-cepacia-like-mb-01-strain-for-shobicron-and-vertimec-degradation/
COCA Clinical Reminder: August 12, 2016 | CDC Emergency Preparedness & ResponseCOCA Clinical Reminder: August 12, 2016 | CDC Emergency Preparedness & Response
The agency confirmed the product had been contaminated with Burkholderia cepacia, a bacteria linked to an outbreak in five ... Multistate Outbreak of Burkholderia cepacia Infections. On July 16, 2016, FDA alerted healthcare professionals that PharmaTech ... due to possible Burkholderia cepacia contamination.. Actions Healthcare Professionals Should Take. Consumers, pharmacies, and ... recall of all liquid products manufactured by PharmaTech and distributed by 6 companies due to possible Burkholderia cepacia ...
https://www.emergency.cdc.gov/coca/reminders/2016/2016august12.asp
Mavidon Issues Voluntary Worldwide Recall of Manufactured Products Including Lemonprep® Tubes And Single Use Cups Pediaprep®...Mavidon Issues Voluntary Worldwide Recall of Manufactured Products Including Lemonprep® Tubes And Single Use Cups Pediaprep®...
Collodion removers due to contamination with Burkholderia cepacia. ... Burkholderia cepacia is a multi-drug resistant pathogenic microorganism. Contaminated products with Burkholderia cepacia can ... Tubes And Single Use Cups Cardio Prep Single Use Cups Due To Burkholderia Cepacia Contamination. When a company announces a ... 2019 were tested and found to be contaminated with Burkholderia cepacia. Out of an abundance of caution, we are recalling all ...
https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/mavidon-issues-voluntary-worldwide-recall-manufactured-products-including-lemonprepr-tubes-and
Burkholderia cepacia endophthalmitis, in a penicillin allergic patient, following a ranibizumab injection<...
N2 - Burkholderia cepacia, a Gram-negative bacterium commonly found in water and soil, is a rare cause of endophthalmitis. The ... AB - Burkholderia cepacia, a Gram-negative bacterium commonly found in water and soil, is a rare cause of endophthalmitis. The ... Burkholderia cepacia, a Gram-negative bacterium commonly found in water and soil, is a rare cause of endophthalmitis. The ... Burkholderia cepacia endophthalmitis, in a penicillin allergic patient, following a ranibizumab injection. In: BMJ Case Reports ...
https://scholars.mssm.edu/en/publications/burkholderia-cepacia-endophthalmitis-in-a-penicillin-allergic-pat-2
Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from...
Burkholderia stagnalis sp. nov. and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from ... and Burkholderia territorii sp. nov., two novel Burkholderia cepacia complex species from environmental and human sources. ... Dive into the research topics of Burkholderia stagnalis sp. nov. ...
https://experts.nau.edu/en/publications/burkholderia-stagnalis-sp-nov-and-burkholderia-territorii-sp-nov-/fingerprints/
Conventional Versus Molecular Methods for Diagnosis of Burkholderia cepacia from Different Clinical Samples of Iraqi Patients -...Conventional Versus Molecular Methods for Diagnosis of Burkholderia cepacia from Different Clinical Samples of Iraqi Patients -...
... cepacia from other (G-) bacteria, and 30/80 recA gene to differentiated B. cepacia from B. cepacia complex. ... The results revealed that 42/80 specimens of the total number of samples are Burkholderia cepacia by using 16SrRNA gene to ... Conventional Versus Molecular Methods for Diagnosis of Burkholderia cepacia from Different Clinical Samples of Iraqi Patients ... The study aims at isolating and identification of Burkholderia cepacia bacteria from clinical samples from various pathological ...
https://irapa.org/conventional-versus-molecular-methods-for-diagnosis-of-burkholderia-cepacia-from-different-clinical-samples-of-iraqi-patients/
SciELO - Brazil - Ants in a hospital environment and their potential as mechanical bacterial vectors Ants in a hospital...SciELO - Brazil - Ants in a hospital environment and their potential as mechanical bacterial vectors Ants in a hospital...
Burkholderia cepacia 2. -. 2. 0.9. -. 3. 3. 0.7. Serratia marcescens 1. -. 1. 0.5. 6. -. 6. 1.4. ...
https://www.scielo.br/j/rsbmt/a/CmPTVdNRdK4TjHftFh4qxmr/?lang=en
Vol. 2 No. 1 (2010) | Journal of Scientific Research Vol. 2 No. 1 (2010) | Journal of Scientific Research
Natural Phthalate Derivatives from the Bacterium Burkholderia cepacia K87 M. Z. Sultan, S. -S. Moon, K. Park ...
https://banglajol.info/index.php/JSR/issue/view/254
PseudomonasSpeciesOrganismContaminated with Burkholderia cepaciaInternational Burkholderia cepacia Working GroupCystic fibrosisInfectionsInfectionPseudomalleiMultivoransBacteria from clinical samplesContaminationGenomovarCenocepaciaNosocomialGram-negative2019BacteriumClinical2017OutbreaksOutbreakMicroorganismAntimicrobialBiofilmPathogenSusceptibilityEndophthalmitisSpecimensAntibioticDetectionVirulenceStrainPresentationGenusSoilExposureGroupFoundColonizer
Pseudomonas10
  • A few Burkholderia species, especially Burkholderia pseudomallei, Burkholderia thailandensis, Burkholderia ambifaria, and Burkholderia cepacia, are known to produce and release various 4-hydroxy-3-methyl-2-alkylquinolines (HMAQs), a family of molecules analogous to the 4-hydroxy-2-alkylquinolines [aka 2-n-alkyl-4(1H)-quinolones] of Pseudomonas aeruginosa, which include the Pseudomonas quinolone signal (PQS). (inrs.ca)
  • Unlike Pseudomonas aeruginosa , B cepacia is an organism of low virulence with a limited ability to cause infection in humans. (medscape.com)
  • Subacute and acute endocarditis due to Pseudomonas cepacia in heroin addicts. (medscape.com)
  • Pseudomonas cepacia endocarditis treated with co-trimoxazole and kanamycin. (medscape.com)
  • Hobson R, Gould I, Govan J. Burkholderia (Pseudomonas) cepacia as a cause of brain abscesses secondary to chronic suppurative otitis media. (medscape.com)
  • IMSEAR at SEARO: Burkholderia cepacia complex: Beyond pseudomonas and acinetobacter. (who.int)
  • Gautam V, Singhal L, Ray P. Burkholderia cepacia complex: Beyond pseudomonas and acinetobacter. (who.int)
  • B. cepacia is difficult to isolate on routinely used laboratory media like MacConkey Agar, since B.cepacia is a slow grower and therefore it is usually outgrown by the faster growing Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. (tmmedia.in)
  • Most confusion surrounding this species name was initially due to its transfer from the genus Pseudomonas to the newly described genus Burkholderia by Yabuuchi et al. (cdc.gov)
  • In the bronchoalveolar lavage fluid, Legionella pneumophila serogroup-1, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Burkholderia cepacia and filamentous fungi Scedosporium apiospermum and Scedosporium prolificans were detected. (who.int)
Species15
  • Isolates of B cepacia complex from individuals with cystic fibrosis are typically more resistant compared to isolates from those without cystic fibrosis, most likely due to previous exposure to antibiotics and variations in the species of B cepacia complex found in these patient groups. (medscape.com)
  • The Burkholderia cepacia complex (Bcc) is a group of closely related gram-negative bacteria comprising at least 9 species ( 1 ). (cdc.gov)
  • LiPuma JJ, Spilker T, Gill LH, Campbell PW 3rd, Liu L, Mahenthiralingam E. Disproportionate distribution of Burkholderia cepacia complex species and transmissibility markers in cystic fibrosis. (medscape.com)
  • Burkholderia cepacia is an important opportunistic pathogen and causes pulmonary infection among individuals with cystic ffibrosis (CF). Burkholderia cepacia species are gram negative, rod shaped bacteria. (tmmedia.in)
  • Burkholderia cepacia species may cause severe infection in individuals with cystic ffibrosis and immunosuppressed individuals. (tmmedia.in)
  • Burkholderia cepacia is a group of organisms that comprises seven genotypically distinct species (B cepacia genomovars I-VII), which are collectively known as the B cepacia complex. (ncl.ac.uk)
  • test evaluates a product for the presence or absence of potential pathogens, specifically those in the Burkholderia cepacia Complex, a complex comprised of 20+ species of strong water-borne opportunistic pathogens. (microchemlab.com)
  • The practice of renaming individual BBC genomovars with species names when phenotypic differentiation becomes available has heightened the confusion, as in the renaming of B. cepacia genomovar II to B. multivorans, where problems arise both with physicians (in infection control) and with patients (psychological acceptance of the disease). (cdc.gov)
  • The correct pronunciation of both the genus Burkholderia and the species cepacia is still debated. (cdc.gov)
  • B cepacia should be included among the bacterial species that may cause endophthalmitis after intravitreal injections. (mssm.edu)
  • Combination antimicrobial susceptibility testing of Burkholderia cepacia complex: significance of species. (abdn.ac.uk)
  • The Burkholderia cepacia complex ( B. cepacia ) consists of different species of bacteria that are found in the natural environment. (cff.org)
  • Butt AT & Thomas MS (2017) Iron Acquisition Mechanisms and Their Role in the Virulence of Burkholderia Species . (sheffield.ac.uk)
  • A species of BURKHOLDERIA considered to be an opportunistic human pathogen. (bvsalud.org)
  • nov., a novel species of the Burkholderia cepacia complex isolated from hospital settings and agricultural soils. (bvsalud.org)
Organism4
  • Burkholderia cepacia, a catalase-producing organism, is known to infect patients with dysfunctional immune systems. (elsevier.com)
  • The organism may lead to Burkholderia cepacia syndrome, a neutralizing pneumonia associated with fever that culminates in to a rapid and fatal clinical deterioration. (tmmedia.in)
  • B. cepacian was the most commonly isolated organism across the studies, with B. cepacia, B. contaminans, and B. stabilis all also being identified. (civco.com)
  • Other characteristic CGD organism include Staphylococcus aureus, Burkholderia cepacia complex, Serratia marcescens, Nocardia and Aspergillus. (primaryimmune.org)
Contaminated with Burkholderia cepacia1
  • For more information see the Notice to Readers: Manufacturer's Recall of Nasal Spray Contaminated with Burkholderia cepacia Complex . (cdc.gov)
International Burkholderia cepacia Working Group2
  • The International Burkholderia cepacia Working Group is open to clinicians and scientists interested in advancing knowledge of BCC infection/colonisation in persons with CF through the collegial exchange of information and promotion of coordinated approaches to research. (who.int)
  • Welcome to the new website of the International Burkholderia cepacia Working Group. (ibcwg.org)
Cystic fibrosis7
  • However, people who have certain health problems like weakened immune systems or chronic lung diseases, particularly cystic fibrosis external icon , may be more susceptible to infections with B. cepacia . (cdc.gov)
  • The effects of B. cepacia on people vary widely, ranging from no symptoms at all to serious respiratory infections, especially in patients with cystic fibrosis. (cdc.gov)
  • Temocillin may offer potential benefits for patients with cystic fibrosis (CF) who are infected with Burkholderia cepacia complex (Bcc). (medscape.com)
  • Burkholderia dolosa is a member of the Burkholderia cepacia complex (BCC), which is a group of bacteria that cause chronic lung infection in patients with cystic fibrosis (CF) and can be associated with outbreaks carrying high morbidity and mortality. (harvard.edu)
  • Subdural empyema due to Burkholderia cepacia: an unusual complication after lung transplantation for cystic fibrosis. (medscape.com)
  • Preoperative infection with B cepacia Is associated with a poor prognosis in lung transplant recipients with cystic fibrosis. (ncl.ac.uk)
  • Burkholderia cepacia , an important gram-negative bacterial pathogen in patients with cystic fibrosis, may cause premature death in these patients. (cdc.gov)
Infections8
  • B cepacia is a known cause of infections in hospitalized patients. (cdc.gov)
  • In 2005, CDC was notified by several states of clusters of pneumonia and other infections caused by B. cepacia and associated with contaminated mouthwash. (cdc.gov)
  • Also in 2004, B. cepacia was linked to nosocomial infections among intensive care unit patients and associated with exposure to sublingual probes. (cdc.gov)
  • For more information see the Notice to Readers: Nosocomial Burkholderia cepacia Infections Associated with Exposure to Sublingual Probes - Texas, 2004 . (cdc.gov)
  • Decisions on the treatment of infections with B. cepacia should be made on a case-by-case basis. (cdc.gov)
  • Members of the Burkholderia cepacia complex (Bcc), found in many environments, are associated with clinical infections. (cdc.gov)
  • Contaminated products with Burkholderia cepacia can potentially result in serious infections, may be life-threatening for patients with compromised immune systems, such as neonates, elderly, pregnant women, cancer patients, but also in previously healthy individuals. (fda.gov)
  • The Kansas Department of Health and Environment, the Texas Department of State Health Services, and the Minnesota Department of Health, with assistance from the Centers for Disease Control and Prevention (CDC), are investigating three cases of Burkholderia pseudomallei (melioidosis) infections. (cdc.gov)
Infection2
  • Potential of the Burkholderia cepacia Complex to Produce 4-Hydroxy-3-Methyl-2-Alkyquinolines Frontiers in Cellular and Infection Microbiology , vol. 9 , nº 33. (inrs.ca)
  • Moisturizing body milk as a reservoir of Burkholderia cepacia: outbreak of nosocomial infection in a multidisciplinary intensive care unit. (medscape.com)
Pseudomallei2
  • Shalom G, Shaw JG & Thomas MS (2007) In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages. . (sheffield.ac.uk)
  • Burkholderia pseudomallei , the causative agent of melioidosis, is a Tier 1 select agent external icon which can affect both animals and humans. (cdc.gov)
Multivorans1
  • This test method has defined procedures for the detection of B. cepacia, B. cenocepacia, and B. multivorans. (microchemlab.com)
Bacteria from clinical samples2
  • The study aims at isolating and identification of Burkholderia cepacia bacteria from clinical samples from various pathological conditions such as diabetic foot ulcers, burn, wound, sputum and urine. (irapa.org)
  • Evaluation of commercial systems VITEK 2 and API 20NE for identification of Burkholderia cepacia complex bacteria from clinical samples]. (bvsalud.org)
Contamination5
  • In 2004, CDC was notified of a voluntary recall of over-the-counter nasal spray due to contamination with B. cepacia complex. (cdc.gov)
  • In December 2020, the FDA issued a recall for the topical skin product Regenecare HA Hydrogel because of Burkholderia Cepacia contamination that could reach the bloodstream. (gedlawyers.com)
  • On August 9, 2016, FDA issued a statement alerting healthcare professionals and consumers of a voluntary nationwide recall of all liquid products manufactured by PharmaTech and distributed by the following companies: Rugby, Major, Bayshore, Metron, Centurion, and Virtus, due to possible Burkholderia cepacia contamination. (cdc.gov)
  • Hospital and clinics to STOP using LemonPrep, Pedia Prep, Wave Prep, Cardio Prep manufactured by Mavidon in the Riviera Beach, FL Facility IMMEDIATELY due to potential contamination with Burkholderia cepacia . (fda.gov)
  • Mavidon is voluntarily recalling all lots of products manufactured at our facility including LemonPrep®, PediaPrep® and Wave Prep 4-ounce tubes and single use cups, Cardio Prep single use cups due to potential contamination with Burkholderia cepacia . (fda.gov)
Genomovar1
  • We studied archived isolates with PCR-based methods, and recorded excessive mortality in patients infected with B cepacia genomovar III, but not in those infected with other genomovars. (ncl.ac.uk)
Cenocepacia4
  • Spiewak HL, Shastri S, Zhang L, Schwager S, Eberl L, Vergunst AC & Thomas MS (2019) Burkholderia cenocepacia utilizes a type VI secretion system for bacterial competition . (sheffield.ac.uk)
  • Tyrrell J, Whelan N, Wright C, Sá-Correia I, McClean S, Thomas M & Callaghan M (2015) Investigation of the multifaceted iron acquisition strategies of Burkholderia cenocepacia . (sheffield.ac.uk)
  • Łochowska A, Iwanicka-Nowicka R, Zielak A, Modelewska A, Thomas MS & Hryniewicz MM (2011) Regulation of sulfur assimilation pathways in Burkholderia cenocepacia through control of genes by the SsuR transcription factor. . (sheffield.ac.uk)
  • Asghar AH, Shastri S, Dave E, Wowk I, Agnoli K, Cook AM & Thomas MS (2011) The pobA gene of Burkholderia cenocepacia encodes a group I Sfp-type phosphopantetheinyltransferase required for biosynthesis of the siderophores ornibactin and pyochelin. . (sheffield.ac.uk)
Nosocomial1
  • Burkholderia cepacia complex (BCC) is an important nosocomial pathogen in hospitalised patients, particularly those with prior broad-spectrum antibacterial therapy. (who.int)
Gram-negative1
  • Burkholderia cepacia, a Gram-negative bacterium commonly found in water and soil, is a rare cause of endophthalmitis. (mssm.edu)
20191
  • We were notified on December 19, 2019 that samples of 114gm tubes of Lemon Prep, collected during a Food and Drug Administration inspection that occurred at our facility on October 15, 2019 were tested and found to be contaminated with Burkholderia cepacia . (fda.gov)
Bacterium1
  • The bacterium Burkholderia cepacia and the fungus Trichoderma virens were investigated for activity against the nematode Meloidogyne incognita and it was found that the inhibitory factors in the in vitroassays were non-enzymic. (semanticscholar.org)
Clinical2
  • Clinical characteristics and outcomes of patients with Burkholderia cepacia bacteremia in an intensive care unit. (medscape.com)
  • However, uncertainty still surrounds the clinical relevance of its evolving taxonomy, particularly in regards to the nine described genomovars of the B. cepacia complex (BCC). (cdc.gov)
20171
  • Shastri S, Spiewak HL, Sofoluwe A, Eidsvaag VA, Asghar AH, Pereira T, Bull EH, Butt AT & Thomas MS (2017) An efficient system for the generation of marked genetic mutants in members of the genus Burkholderia . (sheffield.ac.uk)
Outbreaks3
  • An update will be posted at https://www.cdc.gov/hai/outbreaks/b-cepacia/index.html in approximately one week. (cdc.gov)
  • In this systematic review, the authors examine 14 studies pertaining to outbreaks of Burkholderia cepacian complex in healthcare facilities, all of which were determined to have directly resulted from contaminated ultrasound gel. (civco.com)
  • Each of the 14 Burkholderia cepacian complex (Bcc) outbreaks examined was determined to have resulted from ultrasound gel that had become contaminated. (civco.com)
Outbreak5
  • Characteristics and outcome predictors of patients involved in an outbreak of Burkholderia cepacia complex. (medscape.com)
  • Outbreak of Burkholderia cepacia complex among ventilated pediatric patients linked to hospital sinks. (medscape.com)
  • The agency confirmed the product had been contaminated with Burkholderia cepacia , a bacteria linked to an outbreak in five states. (cdc.gov)
  • We describe an outbreak of Burkholderia stabilis associated with contaminated washing gloves, a commercially available Class I medical device. (eurosurveillance.org)
  • Triggered by an increase in Burkholderia cepacia complex (BCC) bacteremias and the detection of BCC in unopened packages of washing gloves, an ad hoc national outbreak committee comprising representatives of a public health organisation, a regulatory agency, and an expert association convened and commissioned an outbreak investigation. (eurosurveillance.org)
Microorganism1
  • Burkholderia cepacia is a multi-drug resistant pathogenic microorganism. (fda.gov)
Antimicrobial2
  • Burkholderia cepacia have the potential of overcoming antimicrobial preservative systems and antiseptics, and can grow in preserved aqueous oral liquids and topical products. (tmmedia.in)
  • Draft genome sequence reveals co-occurrence of multiple antimicrobial resistance and plant probiotic traits in rice root endophytic strain Burkholderia sp. (ai4society.ca)
Biofilm1
  • OligoG has previously shown potentiation of aztreonam against Burkholderia cepacia complex (Bcc) through biofilm disruption. (cardiff.ac.uk)
Pathogen1
  • Even though in B. cepacia , taxonomic issues rather than pronunciation are at the root of confusion, the pathogen neatly encapsulates several aspects of the linguistic conundrum involving "correct" pronunciation of Latin binomials. (cdc.gov)
Susceptibility1
  • B cepacia often is susceptible to trimethoprim-sulfamethoxazole (TMP-SMX), cefepime, meropenem, minocycline, and tigecycline and has varying susceptibility to ceftazidime and fluoroquinolones. (medscape.com)
Endophthalmitis4
  • Two cases of Burkholderia cepacia endophthalmitis. (medscape.com)
  • Yilmaz T, Celik I, Cihangiroglu M, Yildirim S, Akbulut A. Burkholderia cepacia: An unusual cause of postoperative endophthalmitis. (medscape.com)
  • The authors report a case of a penicillin-allergic patient who presented 15 days after an uneventful injection of ranibizumab for neovascular age-related macular degeneration with culture-positive B cepacia endophthalmitis. (mssm.edu)
  • Saffra, N & Moriarty, E 2014, ' Burkholderia cepacia endophthalmitis, in a penicillin allergic patient, following a ranibizumab injection ', BMJ Case Reports . (mssm.edu)
Specimens1
  • The results revealed that 42/80 specimens of the total number of samples are Burkholderia cepacia by using 16SrRNA gene to differentiate the B. cepacia from other (G-) bacteria, and 30/80 recA gene to differentiated B. cepacia from B. cepacia complex. (irapa.org)
Antibiotic1
  • Mechanisms and regulation of antibiotic resistance in Burkholderia . (sheffield.ac.uk)
Detection1
  • This medium is recommended for detection of Burkholderia cepacia in pharmaceutical products. (tmmedia.in)
Virulence1
  • However, while these exoproducts play several roles in P. aeruginosa virulence and survival, the available literature is very limited on their distribution and function in Burkholderia. (inrs.ca)
Strain1
  • The strain was identified as Burkholderia Cepacia -Like MB-01 based on morphological, physiological, and biochemical traits, as well as phylogenetic analysis of the 16S rRNA sequence. (bsmiab.org)
Presentation1
  • Vining, M , Sharma, N & Guill, M 2014, ' Atypical presentation of chronic granulomatous disease with Burkholderia cepacia ', BMJ Case Reports . (elsevier.com)
Genus1
  • The debate is mainly about the correct pronunciation of cepacia , but the genus name, Burkholderia , also deserves some consideration. (cdc.gov)
Soil2
  • Burkholderia cepacia [burk-hōld-er-ee-uh si-pay-shee-uh] (also called B. cepacia) is the name for a group or "complex" of bacteria that can be found in soil and water. (cdc.gov)
  • According to the FDA, Burkholderia Cepacia is a bacteria that is found in soil and water. (gedlawyers.com)
Exposure2
  • Exposure to B. cepacia in the environment. (cdc.gov)
  • One example of a breakdown in the manufacturing process that has sickened people is exposure to the bacteria called Burkholderia Cepacia. (gedlawyers.com)
Group1
  • In this perspective article, we studied the distribution of the hmqABCDEFG operon, which encodes the enzymes involved in the biosynthesis of HMAQs, in the Burkholderia cepacia complex (Bcc) group. (inrs.ca)
Found2
  • Ceftazidime-avibactam has shown activity against multidrug-resistant B cepacia complex strains and was found to be useful in persistent bacteremia. (medscape.com)
  • This medium was found to be superior to MacConkey Agar for growth of B. cepacia. (tmmedia.in)
Colonizer1
  • Because B cepacia is normally a colonizer, no complications are expected. (medscape.com)
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