A species of gram-negative, aerobic bacteria that causes MELIOIDOSIS. It has been isolated from soil and water in tropical regions, particularly Southeast Asia.
A disease of humans and animals that resembles GLANDERS. It is caused by BURKHOLDERIA PSEUDOMALLEI and may range from a dormant infection to a condition that causes multiple abscesses, pneumonia, and bacteremia.
A genus of gram-negative, aerobic, rod-shaped bacteria. Organisms in this genus had originally been classified as members of the PSEUDOMONAS genus but overwhelming biochemical and chemical findings indicated the need to separate them from other Pseudomonas species, and hence, this new genus was created.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
A species of gram-negative bacteria parasitic on HORSES and DONKEYS causing GLANDERS, which can be transmitted to humans.
Infections with bacteria of the genus BURKHOLDERIA.
An essential amino acid that is physiologically active in the L-form.
A species of BURKHOLDERIA considered to be an opportunistic human pathogen. It has been associated with various types of infections of nosocomial origin.
A contagious disease of horses that can be transmitted to humans. It is caused by BURKHOLDERIA MALLEI and characterized by ulceration of the respiratory mucosa and an eruption of nodules on the skin.
A species of gram-negative bacteria that causes disease in plants. It is found commonly in the environment and is an opportunistic pathogen in humans.
A group of phenotypically similar but genotypically distinct species (genomovars) in the genus BURKHOLDERIA. They are found in water, soil, and the rhizosphere of crop plants. They can act as opportunistic human pathogens and as plant growth promoting and biocontrol agents.
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.
CONNECTIVE TISSUE of the anterior compartment of the THIGH that has its origins on the anterior aspect of the iliac crest and anterior superior iliac spine, and its insertion point on the iliotibial tract. It plays a role in medial rotation of the THIGH, steadying the trunk, and in KNEE extension.
Biosynthesis of GLUCOSE from nonhexose or non-carbohydrate precursors, such as LACTATE; PYRUVATE; ALANINE; and GLYCEROL.
The removal of a carboxyl group, usually in the form of carbon dioxide, from a chemical compound.
In bacteria, a group of metabolically related genes, with a common promoter, whose transcription into a single polycistronic MESSENGER RNA is under the control of an OPERATOR REGION.
Enzymes that catalyze the dehydrogenation of GLYCERALDEHYDE 3-PHOSPHATE. Several types of glyceraldehyde-3-phosphate-dehydrogenase exist including phosphorylating and non-phosphorylating varieties and ones that transfer hydrogen to NADP and ones that transfer hydrogen to NAD.

Burkholderia cocovenenans (van Damme et al. 1960) Gillis et al. 1995 and Burkholderia vandii Urakami et al. 1994 are junior synonyms of Burkholderia gladioli (Severini 1913) Yabuuchi et al. 1993 and Burkholderia plantarii (Azegami et al. 1987) Urakami et al. 1994, respectively. (1/537)

Reference strains of Burkholderia cocovenenans and Burkholderia vandii were compared with strains of other Burkholderia species using SDS-PAGE of whole-cell proteins, DNA-DNA hybridization and extensive biochemical characterization. Burkholderia gladioli and B. cocovenenans were indistinguishable in the chemotaxonomic and biochemical analyses. Burkholderia plantarii and B. vandii had indistinguishable whole-cell protein patterns but the B. vandii type strain differed from B. plantarii strains in several biochemical tests. The DNA-DNA binding levels (higher than 70%) indicated that (i) B. gladioli and B. cocovenenans, and (ii) B. plantarii and B. vandii each represent a single species. It is concluded that B. cocovenenans and B. vandii are junior synonyms of B. gladioli and B. plantarii, respectively.  (+info)

All in the family: structural and evolutionary relationships among three modular proteins with diverse functions and variable assembly. (2/537)

The crystal structures of three proteins of diverse function and low sequence similarity were analyzed to evaluate structural and evolutionary relationships. The proteins include a bacterial bleomycin resistance protein, a bacterial extradiol dioxygenase, and human glyoxalase I. Structural comparisons, as well as phylogenetic analyses, strongly indicate that the modern family of proteins represented by these structures arose through a rich evolutionary history that includes multiple gene duplication and fusion events. These events appear to be historically shared in some cases, but parallel and historically independent in others. A significant early event is proposed to be the establishment of metal-binding in an oligomeric ancestor prior to the first gene fusion. Variations in the spatial arrangements of homologous modules are observed that are consistent with the structural principles of three-dimensional domain swapping, but in the unusual context of the formation of larger monomers from smaller dimers or tetramers. The comparisons support a general mechanism for metalloprotein evolution that exploits the symmetry of a homooligomeric protein to originate a metal binding site and relies upon the relaxation of symmetry, as enabled by gene duplication, to establish and refine specific functions.  (+info)

Discrimination of Burkholderia multivorans and Burkholderia vietnamiensis from Burkholderia cepacia genomovars I, III, and IV by PCR. (3/537)

We present a PCR procedure for identification of Burkholderia cepacia, Burkholderia multivorans, and Burkholderia vietnamiensis. 16S and 23S ribosomal DNAs (rDNAs) of B. multivorans and B. vietnamiensis were sequenced and aligned with published sequences for definition of species-specific 18-mer oligonucleotide primers. Specific antisense 16S rDNA primers (for B. cepacia, 5'-AGC ACT CCC RCC TCT CAG-3'; for B. multivorans, 5'-AGC ACT CCC GAA TCT CTT-3') and 23S rDNA primers (for B. vietnamiensis, 5'-TCC TAC CAT GCG TGC AA-3') were paired with a general sense primer of 16S rDNAs (5'-AGR GTT YGA TYM TGG CTC AG-3') or with a sense primer of 23S rDNA (5'-CCT TTG GGT CAT CCT GGA-3'). PCR with these primers under optimized conditions is appropriate to specifically and rapidly identify B. multivorans, B. vietnamiensis, and B. cepacia (genomovars I, III, and IV are not discriminated). In comparison with the polyphasic taxonomic analyses presently necessary for species and genomovar identification within the B. cepacia complex, our procedure is more rapid and easier to perform and may contribute to clarifying the clinical significance of individual members of the complex in cystic fibrosis.  (+info)

Expression and functional analysis of an N-truncated NifA protein of Herbaspirillum seropedicae. (4/537)

In Herbaspirillum seropedicae, an endophytic diazotroph, nif gene expression is under the control of the transcriptional activator NifA. We have over-expressed and purified a protein containing the central and C-terminal domains of the H. seropedicae NifA protein, N-truncated NifA, fused to a His-Tag sequence. This fusion protein was found to be partially soluble and was purified by affinity chromatography. Band shift and footprinting assays showed that the N-truncated NifA protein was able to bind specifically to the H. seropedicae nifB promoter region. In vivo analysis showed that this protein activated the nifH promoter of Klebsiella pneumoniae in Escherichia coli only in the absence of oxygen and this activation was not negatively controlled by ammonium ions.  (+info)

Burkholderia caribensis sp. nov., an exopolysaccharide-producing bacterium isolated from vertisol microaggregates in Martinique. (5/537)

Twenty-one exopolysaccharide-producing strains were isolated from the 5-20 microns fraction of a vertisol in the south-east of the island of Martinique in the French West Indies. Although these strains were phenotypically identified as Burkholderia cepacia or as Burkholderia glathei using BIOLOG microplates, they did not cluster genotypically by amplified rDNA restriction analysis (ARDRA) with any described Burkholderia species. A phylogenetic analysis revealed that the rrs (16S rDNA) sequences of three representative strains clustered in a single branch within the genus Burkholderia and distantly from all of the previously described species of Burkholderia for which rrs sequences were available. DNA-DNA hybridization data as well as phenotypic analyses indicated that the 21 isolates represented a single and new species for which the name Burkholderia caribensis sp. nov. is proposed (type strain MWAP64T = LMG 18531T).  (+info)

Degradation of chlorobenzenes at nanomolar concentrations by Burkholderia sp. strain PS14 in liquid cultures and in soil. (6/537)

The utilization of 1,2,4,5-tetrachloro-, 1,2,4-trichloro-, the three isomeric dichlorobenzenes and fructose as the sole carbon and energy sources at nanomolar concentrations was studied in batch experiments with Burkholderia sp. strain PS14. In liquid culture, all chlorobenzenes were metabolized within 1 h from their initial concentration of 500 nM to below their detection limits of 0.5 nM for 1,2,4,5-tetrachloro- and 1,2,4-trichlorobenzene and 7.5 nM for the three dichlorobenzene isomers, with 63% mineralization of the tetra- and trichloroisomers. Fructose at the same initial concentration was, in contrast, metabolized over a 4-h incubation period down to a residual concentration of approximately 125 nM with 38% mineralization during this time. In soil microcosms, Burkholderia sp. strain PS14 metabolized tetrachlorobenzene present at 64.8 ppb and trichlorobenzene present at 54.4 ppb over a 72-h incubation period to below the detection limits of 0.108 and 0.09 ppb, respectively, with approximately 80% mineralization. A high sorptive capacity of Burkholderia sp. strain PS14 for 1,2,4, 5-tetrachlorobenzene was found at very low cell density. The results demonstrate that Burkholderia sp. strain PS14 exhibits a very high affinity for chlorobenzenes at nanomolar concentrations.  (+info)

Identification of Burkholderia spp. in the clinical microbiology laboratory: comparison of conventional and molecular methods. (7/537)

Cystic fibrosis (CF) predisposes patients to bacterial colonization and infection of the lower airways. Several species belonging to the genus Burkholderia are potential CF-related pathogens, but microbiological identification may be complicated. This situation is not in the least due to the poorly defined taxonomic status of these bacteria, and further validation of the available diagnostic assays is required. A total of 114 geographically diverse bacterial isolates, previously identified in reference laboratories as Burkholderia cepacia (n = 51), B. gladioli (n = 14), Ralstonia pickettii (n = 6), B. multivorans (n = 2), Stenotrophomonas maltophilia (n = 3), and Pseudomonas aeruginosa (n = 11), were collected from environmental, clinical, and reference sources. In addition, 27 clinical isolates putatively identified as Burkholderia spp. were recovered from the sputum of Dutch CF patients. All isolates were used to evaluate the accuracy of two selective growth media, four systems for biochemical identification (API 20NE, Vitek GNI, Vitek NFC, and MicroScan), and three different PCR-based assays. The PCR assays amplify different parts of the ribosomal DNA operon, either alone or in combination with cleavage by various restriction enzymes (PCR-restriction fragment length polymorphism [RFLP] analysis). The best system for the biochemical identification of B. cepacia appeared to be the API 20NE test. None of the biochemical assays successfully grouped the B. gladioli strains. The PCR-RFLP method appeared to be the optimal method for accurate nucleic acid-mediated identification of the different Burkholderia spp. With this method, B. gladioli was also reliably classified in a separate group. For the laboratory diagnosis of B. cepacia, we recommend parallel cultures on blood agar medium and selective agar plates. Further identification of colonies with a Burkholderia phenotype should be performed with the API 20NE test. For final confirmation of species identities, PCR amplification of the small-subunit rRNA gene followed by RFLP analysis with various enzymes is recommended.  (+info)

Differentiation of Burkholderia species by PCR-restriction fragment length polymorphism analysis of the 16S rRNA gene and application to cystic fibrosis isolates. (8/537)

Burkholderia cepacia, which is an important pathogen in cystic fibrosis (CF) owing to the potential severity of the infections and the high transmissibility of some clones, has been recently shown to be a complex of five genomic groups, i.e., genomovars I, II (B. multivorans), III, and IV and B. vietnamiensis. B. gladioli is also involved, though rarely, in CF. Since standard laboratory procedures fail to provide an accurate identification of these organisms, we assessed the ability of restriction fragment length polymorphism (RFLP) analysis of amplified 16S ribosomal DNA (rDNA), with the combination of the patterns obtained with six endonucleases, to differentiate Burkholderia species. This method was applied to 16 type and reference strains of the genus Burkholderia and to 51 presumed B. cepacia clinical isolates, each representative of one clone previously determined by PCR ribotyping. The 12 Burkholderia type strains tested were differentiated, including B. cepacia, B. multivorans, B. vietnamiensis, and B. gladioli, but neither the genomovar I and III reference strains nor the genomovar IV reference strain and B. pyrrociniaT were distinguishable. CF clinical isolates were mainly distributed in RFLP group 2 (which includes B. multivoransT) and RFLP group 1 (which includes B. cepacia genomovar I and III reference strains, as well as nosocomial clinical isolates). Two of the five highly transmissible clones in French CF centers belonged to RFLP group 2, and three belonged to RFLP group 1. The remaining isolates either clustered with other Burkholderia species (B. cepacia genomovar IV or B. pyrrocinia, B. vietnamiensis, and B. gladioli) or harbored unique combinations of patterns. Thus, if further validated by hybridization studies, PCR-RFLP of 16S rDNA could be an interesting identification tool and contribute to a better evaluation of the respective clinical risks associated with each Burkholderia species or genomovar in patients with CF.  (+info)

Pathogenic Burkholderia rely on host factors for efficient intracellular replication and are highly refractory to antibiotic treatment. To identify host genes that are required by Burkholderia spp. during infection, we performed a RNA interference (RNAi) screen of the human kinome and identified 35 host kinases that facilitated Burkholderia thailandensis intracellular survival in human monocytic THP-1 cells. We validated a selection of host kinases using imaging flow cytometry to assess efficiency of B. thailandensis survival in the host upon siRNA-mediated knockdown. We focused on the role of the novel protein kinase C isoform, PKC-η, in Burkholderia infection and characterized PKC-η/MARCKS signaling as a key event that promotes the survival of unopsonized B. thailandensis CDC2721121 within host cells. While infection of lung epithelial cells with unopsonized Gram-negative bacteria stimulated phosphorylation of Ser175/160 in the MARCKS effector domain, siRNA-mediated knockdown of PKC-η ...
The bacterium Burkholderia ubonensis is commonly co-isolated from environmental specimens harbouring the melioidosis pathogen, Burkholderia pseudomallei. B. ubonensis has been reported in northern Australia and Thailand but not North America, suggesting similar geographic distribution to B. pseudomallei. Unlike most other Burkholderia cepacia complex (Bcc) species, B. ubonensis is considered non-pathogenic, although its virulence potential has not been tested. Antibiotic resistance in B. ubonensis, particularly towards drugs used to treat the most severe B. pseudomallei infections, has also been poorly characterised. This study examined the population biology of B. ubonensis, and includes the first reported isolates from the Caribbean. Phylogenomic analysis of 264 B. ubonensis genomes identified distinct clades that corresponded with geographic origin, similar to B. pseudomallei. A small proportion (4%) of strains lacked the 920kb chromosome III replicon, with discordance of presence/absence amongst
ID CP000871; SV 1; circular; genomic DNA; STD; PRO; 167422 BP. XX AC CP000871; AAVB01000000-AAVB01000037; XX PR Project:PRJNA17407; XX DT 16-NOV-2007 (Rel. 93, Created) DT 12-DEC-2013 (Rel. 119, Last updated, Version 2) XX DE Burkholderia multivorans ATCC 17616 plasmid pBMUL01, complete sequence. XX KW . XX OS Burkholderia multivorans ATCC 17616 OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex. OG Plasmid pBMUL01 XX RN [1] RP 1-167422 RG US DOE Joint Genome Institute RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., RA Richardson P.; RT Complete sequence of plasmid1 of Burkholderia multivorans ATCC 17616; RL Unpublished. XX RN [2] RP 1-167422 RG US DOE Joint Genome Institute RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., ...
Burkholderia thailandensis is a non-pathogenic environmental saprophyte closely related to Burkholderia pseudomallei, the causative agent of the often fatal animal and human disease melioidosis. To study B. thailandensis genomic variation, we profiled 50 isolates using a pan-genome microarray comprising genomic elements from 28 Burkholderia strains and species. Of 39 genomic regions variably present across the B. thailandensis strains, 13 regions corresponded to known genomic islands, while 26 regions were novel. Variant B. thailandensis isolates exhibited isolated acquisition of a capsular polysaccharide biosynthesis gene cluster (B. pseudomallei-like capsular polysaccharide) closely resembling a similar cluster in B. pseudomallei that is essential for virulence in mammals; presence of this cluster was confirmed by whole genome sequencing of a representative variant strain (B. thailandensis E555). Both whole-genome microarray and multi-locus sequence typing analysis revealed that the variant strains
Product information: Burkholderia ambifaria Putative membrane protein insertion efficiency factor BamMC406_3100 - Gentaur.com - Product info
TY - CONF. T1 - Comparison of biofilm formation between Burkholderia multivorans Burkholderia cenocepacia Pseudomonas aeruginosa in the presence or absence of mucin. AU - Einarsson, Gisli. AU - McDowell, Andrew. AU - Elborn, Joseph. AU - Martin, Lorraine. PY - 2009/6. Y1 - 2009/6. M3 - Paper. SP - S34-S34. T2 - European Cystic Fibrosis Conference. Y2 - 1 June 2009 through 1 June 2009. ER - ...
Cystic fibrosis (CF) is a recessive genetic disease characterized by chronic respiratory infections and inflammation causing permanent lung damage. Recurrent infections are caused by Gram-negative antibiotic-resistant bacterial pathogens such as Pseudomonas aeruginosa, Burkholderia cepacia complex (Bcc) and the emerging pathogen genus Pandoraea. In this study, the interactions between co-colonizing CF pathogens were investigated. Both Pandoraea and Bcc elicited potent pro-inflammatory responses that were significantly greater than Ps. aeruginosa. The original aim was to examine whether combinations of pro-inflammatory pathogens would further exacerbate inflammation. In contrast, when these pathogens were colonized in the presence of Ps. aeruginosa the pro-inflammatory response was significantly decreased. Real-time PCR quantification of bacterial DNA from mixed cultures indicated that Ps. aeruginosa significantly inhibited the growth of Burkholderia multivorans, Burkholderia cenocepacia, Pandoraea
Free Public Domain Picture: This photograph depicts the colonial morphology displayed by Gram-negative Burkholderia thailandensis bacteria, which was grown on a medium | ID: 13545336611235
Burkholderia species have environmental, industrial and medical significance, and are important opportunistic pathogens in individuals with cystic fibrosis (CF). Using a combination of existing and newly determined genome sequences, this study investigated prophage carriage across the species B. vietnamiensis, and also isolated spontaneously inducible prophages from a reference strain, G4. Eighty-one B. vietnamiensis genomes were bioinformatically screened for prophages using PHASTER (Phage Search Tool Enhanced Release) and prophage regions were found to comprise up to 3.4% of total genetic material. Overall, 115 intact prophages were identified and there was evidence of polylysogeny in 32 strains. A novel, inducible Mu-like phage (vB_BvM-G4P1) was isolated from B. vietnamiensis G4 that had lytic activity against strains of five Burkholderia species prevalent in CF infections, including the Boston epidemic B. dolosa strain SLC6. The cognate prophage to vB_BvM-G4P1 was identified in the lysogen genome
Members of the Burkholderia cepacia complex (Bcc), such as B. ambifaria, are effective biocontrol strains, for instance, as plant growth-promoting bacteria; however, Bcc isolates can also cause severe respiratory infections in people suffering from cystic fibrosis (CF). No distinction is known between isolates from environmental and human origins, suggesting that the natural environment is a potential source of infectious Bcc species. While investigating the presence and role of phase variation in B. ambifaria HSJ1, an isolate recovered from a CF patient, we identified stable variants that arose spontaneously irrespective of the culture conditions. Phenotypic and proteomic approaches revealed that the transition from wild-type to variant types affects the expression of several putative virulence factors. By using four different infection models (Drosophila melanogaster, Galleria mellonella, macrophages and Dictyostelium discoideum), we showed that the wild-type was more virulent than the ...
Purchase Recombinant Burkholderia vietnamiensis UPF0060 membrane protein Bcep1808_1236 (Bcep1808_1236). It is produced in Yeast. High purity. Good price.
DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preventing mutations from becoming permanent in dividing cells. MMR also suppresses homologous recombination and was recently shown to play a role in DNA damage signaling. Defects in MMR are associated with genome-wide instability, predisposition to certain types of cancer including HNPCC, resistance to certain chemotherapeutic agents, and abnormalities in meiosis and sterility in mammalian systems. The Escherichia coli MMR pathway has been extensively studied and is well characterized. In E. coli, the mismatch-activated MutS-MutL-ATP complex licenses MutH to incise the nearest unmethylated GATC sequence. UvrD and an exonuclease generate a gap. This gap is filled by pol III and DNA ligase. The GATC sites are then methylated by Dam. Several human MMR proteins have been identified based on their homology to ...
A polyphasic taxonomic study including DNA-DNA reassociation experiments and an extensive biochemical characterization was performed on 14 Burkholderia isolates from moss gametophytes of nutrient-poor plant communities on the southern Baltic Sea coast in northern Germany. The strains were classified within two novel species, for which the names Burkholderia bryophila sp. nov. and Burkholderia megapolitana sp. nov. are proposed. The former species also includes isolates from grassland and agricultural soil collected in previous studies. Strains Burkholderia bryophila 1S18T (=LMG 23644T =CCUG 52993T) and Burkholderia megapolitana A3T (=LMG 23650T =CCUG 53006T) are the proposed type strains. They were isolated from Sphagnum rubellum and Aulacomnium palustre, respectively, growing in the Ribnitzer Großes Moor nature reserve (Mecklenburg-Pommern, Germany). All moss isolates of both novel species showed antifungal activity against phytopathogens as well as plant-growth-promoting properties.
FIG 6 In vitro interaction of occidiofungin with F- and G-actin. (a) Affinity pulldown of actin using alkyne-OF. Lane 1, ladder; lane 2, 100 ng pure F-actin; lane 3, 100 ng pure G-actin; lane 4, empty; lane 5, F-actin treated with alkyne-OF; lane 6, F-actin treated with native occidiofungin; lane 7, F-actin treated with DMSO; lane 8, G-actin treated with alkyne-OF; lane 9, G-actin treated with native occidiofungin; lane 10, G-actin treated with DMSO. (b) Fluorescence microscopy of the effect of occidiofungin treatment on actin filaments visualized by fluorescently labeled phalloidin. (A) Actin filaments treated with solvent blank (DMSO). (B) Actin/native occidiofungin (24 μg actin:4 μg native occidiofungin). (C) Actin/native occidiofungin (24 μg actin:8 μg native occidiofungin). Scale bar, 5 µm. ...
General Information: B. vietnamiensis strain G4 (formerly B.cepacia strain R1808) is the best trichloroethene (TCE) co-oxidizing strain yet discovered, having been isolated from an industrial waste treatment facility at Pensacola Naval Air Station, Florida, U.S.A. Burkholderia vietnamiensis is a member of the Burkholderia cepacia complex which contains a number of closely related Burkholderia species. Burkholderia vietnamiensis is commonly isolated from soil and water and has been studied as a plant growth promoting bacterium and as a bioremediation agent for aromatic hydrocarbons such as benzene and tolulene. ...
Chebbi, Alif, Elshikh, Mohamed, Haque, Farazul, Ahmed, Syed, Dobbin, Sara, Marchant, R, Sayadi, Sami, Chamkha, Mohamed and Banat, Ibrahim M (2017) Rhamnolipids from Pseudomonas aeruginosa strain W10;as antibiofilm/antibiofouling products for metal protection. Journal of Basic Microbiology, 9999 . pp. 1-12. [Journal article] Elshikh, M, Moya-Ramirez, I, Moens, H, Roelants, S, Soetaert, W, Marchant, Roger and Banat, Ibrahim M (2017) Rhamnolipids and Lactonic Sophorolipids: Natural antimicrobial surfactants for oral hygiene. Journal of Applied Microbiology, 123 . [Journal article] Elshikh, Mohamed, Funston, Scott, chebbi, Alif, Ahmed, Syed, Marchant, R and Banat, Ibrahim M (2017) Rhamnolipids from non-pathogenic Burkholderia thailandensis E264: Physicochemical characterization, antimicrobial and antibiofilm efficacy against oral hygiene related pathogens. New Biotechnology, 36 . pp. 26-36. [Journal article] Funston, SJ, Tsaousi, Konstantina, Smyth, TJ, Twigg, Matthew, Marchant, Roger and Banat, ...
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If you have used this database, please ensure that you acknowledge the Burkholderia Genome Database publication rather than just the website URL. Thank you!. Winsor GL, Khaira B, Van Rossum T, Lo R, Whiteside MD, Brinkman FS. (2008 ...
If you have used this database, please ensure that you acknowledge the Burkholderia Genome Database publication rather than just the website URL. Thank you!. Winsor GL, Khaira B, Van Rossum T, Lo R, Whiteside MD, Brinkman FS. (2008 ...
General Information: Burkholderia glumae causes seedling rot and panicle blight of rice. Panicle blight is a significant problem in the southern USA during unusually warm growing seasons. Infection of rice with Burkholderia glumae causes sterility, or abortion, of the rice kernels, and may inhibit seed germination. Burkholderia glumae also produces an industrially important extracellular lipase. ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
In bacterial genomes composed of more than one chromosome, one replicon is typically larger, harbors more essential genes than the others, and is considered primary. The greater variability of secondary chromosomes among related taxa has led to the theory that they serve as an accessory genome for specific niches or conditions. By this rationale, purifying selection should be weaker on genes on secondary chromosomes because of their reduced necessity or usage. To test this hypothesis we selected bacterial genomes composed of multiple chromosomes from two genera, Burkholderia and Vibrio, and quantified the evolutionary rates (dN and dS) of all orthologs within each genus. Both evolutionary rate parameters were faster among orthologs found on secondary chromosomes than those on the primary chromosome. Further, in every bacterial genome with multiple chromosomes that we studied, genes on secondary chromosomes exhibited significantly weaker codon usage bias than those on primary chromosomes. Faster
ID B2TBM3_PARPJ Unreviewed; 220 AA. AC B2TBM3; DT 01-JUL-2008, integrated into UniProtKB/TrEMBL. DT 01-JUL-2008, sequence version 1. DT 25-OCT-2017, entry version 53. DE SubName: Full=Glutathione S-transferase domain {ECO:0000313,EMBL:ACD19675.1}; GN OrderedLocusNames=Bphyt_5316 {ECO:0000313,EMBL:ACD19675.1}; OS Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) OS (Burkholderia phytofirmans). OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Burkholderiaceae; Paraburkholderia. OX NCBI_TaxID=398527 {ECO:0000313,EMBL:ACD19675.1, ECO:0000313,Proteomes:UP000001739}; RN [1] {ECO:0000313,EMBL:ACD19675.1, ECO:0000313,Proteomes:UP000001739} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 17436 / LMG 22146 / PsJN RC {ECO:0000313,Proteomes:UP000001739}; RX PubMed=21551308; DOI=10.1128/JB.05055-11; RA Weilharter A., Mitter B., Shin M.V., Chain P.S., Nowak J., RA Sessitsch A.; RT Complete genome sequence of the plant growth-promoting endophyte RT ...
Vikram S, Kumar S, Vaidya B, Pinnaka AK, Raghava GPS: download commutative ring theory etal investment of the shared Biodegradation increase sustainability. Kumar S, Vikram S, Raghava GPS: DNA island of the robust ,900 clean-up Burkholderia methysticin. L, Seeger M: infected and economic sites of the etal and single cytochrome people and increased significant and 6-TCP important bacteria in Burkholderia xenovorans LB400. B: skilled download commutative ring theory of oxidative courses household from the field of the available food everything Cupriavidus corn JMP134. If you have at an download commutative ring theory or online patch, you can sulphate the judge mode to see a land across the pretreatment challenging for able or economic threats. Another formation to See updating this JJ in the signature has to be Privacy Pass. download commutative out the operation champion in the Chrome Store. BBC NewsNews NavigationSectionsHomeHome History linkage; ArtsHealthWorld News TVIn PicturesReality ...
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Accepted name: 2,4-dinitrotoluene dioxygenase. Reaction: 2,4-dinitrotoluene + NADH + O2 = 4-methyl-5-nitrocatechol + nitrite + NAD+. Other name(s): dntA (gene name). Systematic name: 2,4-dinitrotoluene,NADH:oxygen oxidoreductase (4,5-hydroxylating, nitrite-releasing). Comments: This enzyme, characterized from the bacterium Burkholderia sp. strain DNT, is a member of the naphthalene family of bacterial Rieske non-heme iron dioxygenases. It comprises a multicomponent system, containing a Rieske [2Fe-2S] ferredoxin, an NADH-dependent flavoprotein reductase (EC 1.18.1.3, ferredoxin NAD+ reductase), and an α3β3 oxygenase. The enzyme forms a cis-dihydroxylated product that spontaneously rearranges to form a catechol with accompanying release of nitrite. It does not act on nitrobenzene. cf. EC 1.14.12.23, nitroarene dioxygenase.. Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: References:. 1. Suen, W.C., Haigler, B.E. and Spain, J.C. 2,4-Dinitrotoluene dioxygenase from ...
We are studying a representative of a large group of chlorobenzoate degrading bacteria active in uncontaminated systems - Burkholderia phytofirmans OLGA172. Now we know that anthropogenic chemicals have not always been the driving selective force behind the evolution of chloro-organic degradative genes, we are looking for the natural selectors for these capabilities, initially by looking at the environmental triggers and mobile genetic elements that affect chloroaromatic degradative gene expression. The recent genome sequencing of OLGA172 in the lab has expanded this endeavour.. In addition, my lab carries out research on the species composition of bacterial communities in both natural and contaminated systems. These include waste water treatment systems, contaminated soils, rhizospheric communities and the hyporheic zones of streams.. The UTSC campus is heavily infested with an invasive species known as Dog Strangling Vine. My lab has recently begun research into the microbial associations of ...
Bio-protocol is an online peer-reviewed protocol journal. Its mission is to make life science research more efficient and reproducible by curating and hosting high quality, free access protocols.
Species Fungorum synonymy Index Fungorum LSID: urn:lsid:indexfungorum.org:names:438420; click here to update this record. Index Fungorum UUID: {B50B9A36-FD1F-40F5-95E8-9DB182D3CF41} Please contact Paul Kirk if you have any additions or errors to report. Data contributors.. back to previous page. ...
Species Fungorum synonymy Index Fungorum LSID: urn:lsid:indexfungorum.org:names:110903; click here to update this record. Index Fungorum UUID: {72CA4BF6-B31D-455F-A5DC-5D1C09090735} Please contact Paul Kirk if you have any additions or errors to report. Data contributors.. back to previous page. ...
Tuanyok, Apichai; Mayo, Mark; Scholz, Holger; Hall, Carina M.; Allender, Christopher J.; Kaestli, Mirjam; Ginther, Jennifer; Spring-Pearson, Senanu; Bollig, Molly C.; Stone, Joshua K.; Settles, Erik W.; Busch, Joseph D.; Sidak-Loftis, Lindsay; Sahl, Jason W.; Thomas, Astrid; Kreutzer, Lisa; Georgi, Enrico; Gee, Jay E.; Bowen, Richard A.; Ladner, Jason T.; Lovett, Sean; Koroleva, Galina; Palacios, Gustavo; Wagner, David M.; Currie, Bart J.; Keim, Paul ...
We have to understand the risks, mitigate against them and seek a balance that works for all.. Professor Mahenthiralingam, has studied burkholderia bacteria in cystic fibrosis for many years and the research led to two new human antibiotics , Cepacin A and B. But he and his team are now working to see if Cepacin would be effective in crop pests as well. Using genomic sequencing of the bacterial DNA the researchers could identify the genes for burkholderia to manufacture Cepacin.. Burkholderia split their genomic DNA across 3 fragments, called replicons, said Professor Mahenthiralingam.. We removed the smallest of these 3 replicons to create a mutant Burkholderia strain which, when tested on germinating peas, still demonstrated excellent biopesticidal properties.. Tests in mice susceptible to lung infections, intended to mimic the regular infections faced by people with cystic fibrosis found the mutant strain also did not cause them harm.. ...
Burkholderia cepacia is a gram negative bacilli usually isolated from persons with genetic lung diseases such as Cystic fibrosis. It was discovered as a plant pathogen but later researchers have found it to be a notorious pathogen in humans. It is also a nosocomial pathogen which contaminates equipment and even disinfectants. In the other end of the spectrum, research suggests that these organisms maybe used as bio diesel and also as pesticides and fertilizers. This review of literature gives an idea of the organism and the gateway it opens for further research with a special note on the evolution of this genus as a nosocomial infection in Neonates.
Burkholderia cepacia has emerged during the past 2 decades as an important opportunistic pathogen in persons with cystic fibrosis (CF) (11). Although B. cepacia was previously regarded as a single species, recent taxonomic studies have identified at least nine closely related species in what is now referred to as the B. cepacia complex (Bcc). This group includes B. cepacia, Burkholderia multivorans, Burkholderia cenocepacia, Burkholderia stabilis, Burkholderia vietnamiensis, Burkholderia dolosa, Burkholderia ambifaria, Burkholderia anthina, and Burkholderia pyrrocinia (4-6, 25, 28-32). Although each of these species has been recovered from respiratory secretions of persons with CF, B. multivorans and B. cenocepacia account for the great majority of isolates (12, 24). Mounting evidence also suggests that B. cenocepacia is somewhat more pathogenic in CF than are the remaining species (1, 8).. A feature that distinguishes Bcc from other pathogens in CF is the occurrence in a significant proportion ...
The overall goal of this project is to forensically characterize 100 unknown Burkholderia isolates in the US-Australia collaboration. We will identify genome-wide single nucleotide polymorphisms (SNPs) from B. pseudomallei and near neighbor species including B. mallei, B. thailandensis and B. oklahomensis. We will design microarray probes to detect these SNP markers and analyze 100 Burkholderia genomic DNAs extracted from environmental, clinical and near neighbor isolates from Australian collaborators on the Burkholderia SNP microarray. We will analyze the microarray genotyping results to characterize the genetic diversity of these new isolates and triage the samples for whole genome sequencing. In this interim report, we described the SNP analysis and the microarray probe design for the Burkholderia SNP microarray. ...
TY - JOUR. T1 - Malleilactone is a Burkholderia pseudomallei virulence factor regulated by antibiotics and quorum sensing. AU - Klaus, Jennifer R.. AU - Deay, Jacqueline. AU - Neuenswander, Benjamin. AU - Hursh, Wyatt. AU - Gao, Zhe. AU - Bouddhara, Tiffany. AU - Williams, Todd D.. AU - Douglas, Justin. AU - Monize, Kyle. AU - Martins, Patricia. AU - Majerczyk, Charlotte. AU - Seyedsayamdost, Mohammad R.. AU - Peterson, Blake R.. AU - Rivera, Mario. AU - Chandler, Josephine R.. PY - 2018/7/1. Y1 - 2018/7/1. N2 - Burkholderia pseudomallei, the causative agent of melioidosis, encodes almost a dozen predicted polyketide (PK) biosynthetic gene clusters. Many of these are regulated by LuxR-I-type acyl-homoserine (AHL) quorum-sensing systems. One of the PK gene clusters, the mal gene cluster, is conserved in the close relative Burkholderia thailandensis. The B. thailandensis mal genes code for the cytotoxin malleilactone and are regulated by a genetically linked LuxR-type transcription factor, MalR. ...
A trichloroethylene (TCE)-degrading bacterium was isolated from an aquifer sample collected at a TCE-polluted site in Japan by enriching with phenol as sole carbon source. The isolate, designated strain KP23T, was a Gram-negative, oval-shaped micro-organism. A phylogenetic study based on 16S rRNA ge …
TY - JOUR. T1 - Drug screening to identify compounds to act as co-therapies for the treatment of Burkholderia species. AU - Barker, Sam. AU - Harding, Sarah V.. AU - Gray, David. AU - Richards, Mark I.. AU - Atkins, Helen S.. AU - Harmer, Nicholas J.. N1 - Publisher Copyright: © 2021 Barker et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.. PY - 2021/3/25. Y1 - 2021/3/25. N2 - Burkholderia pseudomallei is a soil-dwelling organism present throughout the tropics. It is the causative agent of melioidosis, a disease that is believed to kill 89,000 people per year. It is naturally resistant to many antibiotics, requiring at least two weeks of intravenous treatment with ceftazidime, imipenem or meropenem followed by 6 months of orally delivered ...
The trend to search novel microbial natural biocides has recently been increasing in order to avoid the environmental pollution from use of synthetic pesticides. Among these novel natural biocides are the bioactive secondary metabolites of Burkholderia gladioli pv. agaricicola (Bga). The aim of this study is to determine antifungal activity of Bga strains against some phytopathogenic fungi. The fungicidal tests were carried out using cultures and cell-free culture filtrates against Botrytis cinerea, Aspergillus flavus, Aspergillus niger, Penicillium digitatum, Penicillium expansum, Sclerotinia sclerotiorum and Phytophthora cactorum. Results demonstrated that all tested strains exert antifungal activity against all studied fungi by producing diffusible metabolites which are correlated with their ability to produce extracellular hydrolytic enzymes. All strains significantly reduced the growth of studied fungi and the bacterial cells were more bioactive than bacterial filtrates. All tested Bulkholderia
Wallqvist, A., H. Wang, N. Zavaljevski, V. Memisevic, K. Kwon, R. Pieper, S. V. Rajagopala, and J. Reifman. Mechanisms of action of Coxiella burnetii effectors inferred from host-pathogen protein interactions. PLOS ONE. 2017 November 27; 12(11):e0188071. [PDF]. Memisevic, V., K. Kumar, N. Zavaljevski, D. DeShazer, A. Wallqvist, and J. Reifman. DBSecSys 2.0: a database of Burkholderia mallei and Burkholderia pseudomallei secretion systems. BMC Bioinformatics. 2016 September 20; 17:387. [PDF]. Wallqvist, A., V. Memisevic, N. Zavaljevski, R. Pieper, S. V. Rajagopala, K. Kwon, C. Yu, T. A. Hoover, and J. Reifman. Using host-pathogen protein interactions to identify and characterize Francisella tularensis virulence factors. BMC Genomics. 2015 December 29; 16:1106. [PDF]. Chiang, C. Y., I. Uzoma, D. J. Lane, V. Memisevic, F. Alem, K. Yao, S. Bavari, A. Wallqvist, R. M. Hakami, and R. G. Panchal. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. ...
According to Coenye et al. (1999), this species is a later heterotypic synonym of Burkholderia gladioli (Severini 1913) Yabuuchi et al. 1993. Publication: Coenye T, Holmes B, Kersters K, Govan JR, Vandamme P. Burkholderia cocovenenans (van Damme et al. 1960) Gillis et al. 1995 and Burkholderia vandii Urakami et al. 1994 are junior synonyms of Burkholderia gladioli (Severini 1913) Yabuuchi et al. 1993 and Burkholderia plantarii (Azegami et al. 1987) Urakami et al. 1994, respectively. Int J Syst Bacteriol 1999; 49:37-42. ...
The bacterium Burkholderia multivorans evolves and adapts in bursts to survive in the lungs of cystic fibrosis patients, according to a study published in...
Quorum sensing (QS) is a cell density-dependent mechanism which enables a population of bacteria to coordinate cooperative behaviors in response to the accumulation of self-produced autoinducer signals in their local environment. An emerging framework is that the adaptive significance of QS in the regulation of production of costly extracellular metabolites («public goods») is to maintain the homeostasis of cooperation. We investigated this model using the phytopathogenic bacterium Burkholderia glumae, which we have previously demonstrated uses QS to regulate the production of rhamnolipids, extracellular surface-active glycolipids promoting the social behavior called «swarming motility». Using mass spectrometric quantification and chromosomal lux-based gene expression, we made the unexpected finding that when unrestricted nutrient resources are provided, production of rhamnolipids is carried out completely independently of QS regulation. This is a unique observation among known QS-controlled factors
We generated a Burkholderia mutant, which is deficient of an N-acetylmuramyl-l-alanine amidase, AmiC, involved in peptidoglycan degradation. When non-motile ΔamiC mutant Burkholderia cells harboring chain form were orally administered to Riptortus insects, ΔamiC mutant cells were unable to establish symbiotic association. But, ΔamiC mutant complemented with amiC gene restored in vivo symbiotic association. ΔamiC mutant cultured in minimal medium restored their motility with single-celled morphology. When ΔamiC mutant cells harboring single-celled morphology were administered to the host insect, this mutant established normal symbiotic association, suggesting that bacterial motility is essential for the successful symbiosis between host insect and Burkholderia symbiont ...
Molecular identification of bioterrorism agents such as B. anthracis, Brucella spp., Burkholderia spp., Ricin toxin, F. tularensis, Y. pestis, Varicella and Vaccinia virus is currently performed using real-time PCR and EIA protocols developed and distributed by the Laboratory Response Network of the Centers for Disease Control and Prevention (CDC). Our laboratory also performs MSDH-designed assays for the molecular detection of the following infectious agents: Bordetella species, Norovirus, Measles, Mumps, and Shiga-Toxin producing E. coli. Molecular subtyping of the food-borne disease-causing bacteria Salmonella, Shigella, Listeria and E. coli are also performed by our laboratory using pulse-field electrophoresis (PFGE) and is coordinated through PulseNet, the CDCs national foodborne disease detection network. This section also performs influenza A and B virus testing, influenza A subtyping, and influenza B genotyping primarily for surveillance purposes. Results are used to monitor state ...
Molecular identification of bioterrorism agents such as B. anthracis, Brucella spp., Burkholderia spp., Ricin toxin, F. tularensis, Y. pestis, Varicella and Vaccinia virus is currently performed using real-time PCR and EIA protocols developed and distributed by the Laboratory Response Network of the Centers for Disease Control and Prevention (CDC). Our laboratory also performs MSDH-designed assays for the molecular detection of the following infectious agents: Bordetella species, Norovirus, Measles, Mumps, and Shiga-Toxin producing E. coli. Molecular subtyping of the food-borne disease-causing bacteria Salmonella, Shigella, Listeria and E. coli are also performed by our laboratory using pulse-field electrophoresis (PFGE) and is coordinated through PulseNet, the CDCs national foodborne disease detection network. This section also performs influenza A and B virus testing, influenza A subtyping, and influenza B genotyping primarily for surveillance purposes. Results are used to monitor state ...
Molecular identification of bioterrorism agents such as B. anthracis, Brucella spp., Burkholderia spp., Ricin toxin, F. tularensis, Y. pestis, Varicella and Vaccinia virus is currently performed using real-time PCR and EIA protocols developed and distributed by the Laboratory Response Network of the Centers for Disease Control and Prevention (CDC). Our laboratory also performs MSDH-designed assays for the molecular detection of the following infectious agents: Bordetella species, Norovirus, Measles, Mumps, and Shiga-Toxin producing E. coli. Molecular subtyping of the food-borne disease-causing bacteria Salmonella, Shigella, Listeria and E. coli are also performed by our laboratory using pulse-field electrophoresis (PFGE) and is coordinated through PulseNet, the CDCs national foodborne disease detection network. This section also performs influenza A and B virus testing, influenza A subtyping, and influenza B genotyping primarily for surveillance purposes. Results are used to monitor state ...
Biostimulants inducing plant defences is among the promising approaches to reduce the chemical pesticides use in wheat protection against Septoria leaf blotch caused by the hemibiotrophic Zymoseptori tritici. Within this scope, the effect of seed coating with the bacterium Paraburkholderia phytofirmans (PsJN strain) or thyme oil on triggering wheat systemic resistance to Septoria leaf blotch under controlled conditions was investigated using histopathological, physiological and biochemical approaches. Both products reducednecrosis, pycnidial density,associated with induction of programmed cell death, papillae accumulation in the biotrophic stage, and lowerperoxidase activity, H2O2, catalase and phenolic content in the necrotophic stage. Thyme oilinduced systemic acquired resistancewhile PsJN strain triggered induced systemic resistance to Septoria leaf blotch.
The enzyme from Burkholderia fungorum strain LB400 (previously Pseudomonas sp.) is part of a multicomponent system composed of an NADH:ferredoxin oxidoreductase (FAD cofactor), a [2Fe-2S] Rieske-type ferredoxin, and a terminal oxygenase that contains a [2Fe-2S] Rieske- type iron-sulfur cluster and a catalytic mononuclear nonheme iron center. -!- Chlorine-substituted biphenyls can also act as substrates. -!- Similar to the three-component enzyme systems EC 1.14.12.3 and EC 1.14.12.11 ...
Nephroma arcticum (L.) Torss. 1843. Index Fungorum LSID: urn:lsid:indexfungorum.org:names:397161 Please contact Paul Kirk if you have any additions or errors to report. Data contributors.. back to previous page. ...
4-methylphthalate catabolism in Burkholderia (Pseudomonas) cepacia Pc701: a gene encoding a phthalate-specific permease forms part of a novel gene cluster
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Joseph D. Mougous and coworkers at the University of Washington School of Medicine and HHMI discovered a cytidine deaminase, which converts cytosine (C) to uracil (U), in the bacteria Burkholderia cenocepacia and thought the enzyme could be useful for genome editing. Mougous reached out to David R. Liu at the Broad Institute, Harvard University, and HHMI, because Lius group had previously developed base editors, which are engineered proteins that make specific single-letter changes in DNA.. ...
SWISS-MODEL Template Library (SMTL) entry for 1ci8.1. ESTERASE ESTB FROM BURKHOLDERIA GLADIOLI: AN ESTERASE WITH (BETA)-LACTAMASE FOLD.
Patients, Antibiotics, Bacteria, Biofilm, Biofilms, Cystic Fibrosis, Fibrosis, Sputum, Adults, Asthma, Death, Lung, Azithromycin, Burkholderia, Burkholderia Cepacia, Pseudomonas, Pseudomonas Aeruginosa, Rifampin, Treatment, Algorithm
lipopolysaccharide β-1,4-galactosyltransferase (EC 2.4.1.-); β-1,3-glucosyltransferase (EC 2.4.1.-); β-1,2-glucosyltransferase (EC 2.4.1.-); β-1,2-galactosyltransferase (EC 2.4.1.-); LPS β-1,4-galactosyltransferase (EC 2.4.1.-); occidiofungin β-xylosyltransferase (EC 2.4.2.-); UDP-Gal:procollagen β-galactosyltransferase (EC 2.4.1.50 ...
Kirk P.M. (ed.) (2020). Species Fungorum Plus: Species Fungorum for CoL+ (version Feb 20120). In: Species 2000 & ITIS Catalogue of Life, 2020-09-01 Beta (Roskov Y.; Ower G.; Orrell T.; Nicolson D.; Bailly N.; Kirk P.M.; Bourgoin T.; DeWalt R.E.; Decock W.; Nieukerken E. van; Penev L.; eds.). Digital resource at www.catalogueoflife.org/col. Species 2000: Naturalis, Leiden, the Netherlands. ISSN 2405-8858 ...
Index Fungorum Partnership (2018). Index Fungorum. Glugea cladocera Pfeiffer. Accessed through: World Register of Marine Species at: http://www.marinespecies.org/aphia.php?p=taxdetails&id=559097 on 2018-02-20 ...
Kirk, Paul M. (2009). Haloguignardia oceanica (Ferd. & Winge) Kohlm., 1971. In: Index Fungorum Partnership (2017). Index Fungorum. Accessed through: World Register of Marine Species at http://www.marinespecies.org/aphia.php?p=taxdetails&id=177917 on 2017-12- ...
ID Q13S50_PARXL Unreviewed; 203 AA. AC Q13S50; DT 22-AUG-2006, integrated into UniProtKB/TrEMBL. DT 22-AUG-2006, sequence version 1. DT 30-AUG-2017, entry version 79. DE SubName: Full=Two component transcriptional regulator, LuxR family {ECO:0000313,EMBL:ABE33089.1}; GN ORFNames=Bxe_B2906 {ECO:0000313,EMBL:ABE33089.1}; OS Paraburkholderia xenovorans (strain LB400). OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Burkholderiaceae; Paraburkholderia. OX NCBI_TaxID=266265 {ECO:0000313,EMBL:ABE33089.1, ECO:0000313,Proteomes:UP000001817}; RN [1] {ECO:0000313,EMBL:ABE33089.1, ECO:0000313,Proteomes:UP000001817} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=LB400 {ECO:0000313,EMBL:ABE33089.1, RC ECO:0000313,Proteomes:UP000001817}; RX PubMed=17030797; DOI=10.1073/pnas.0606924103; RA Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L., RA Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., RA Lao V., Larimer F., LiPuma J.J., ...
Braffman NR, Piscotta FJ, Hauver J, Campbell EA, A Link J, Darst SA. Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc Natl Acad Sci U S A. 2019 ;116(4):1273-1278. ...
Ah, yes! Im dealing with Burkholderia. 16s rDNA analyses showed similarity to B. cepacia and B. cenocepacia. Perhaps the fact that B. cepacia exists as a complex of many strains (genomovars) that makes biochemical identification inaccurate; what more when I did it the conventional way. Hoping this time that the commercial kit like API could back the 16s analyses up.. ...
"Burkholderia". cict.fr. "Burkholderia endofungorum". Ezbiocloud.net. Laila P. Partida-Martinez; Ingrid Groth; Imke Schmitt; ... Walter Richter; Martin Roth; Christian Hertweck1 (2007). "Burkholderia rhizoxinica sp. nov. and Burkholderia endofungorum sp. ... 2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
J.P. Euzeby (1998-01-01). "Burkholderia". LPSN. Retrieved 2013-06-11. Lu, P; Zheng, LQ; Sun, JJ; Liu, HM; Li, SP; Hong, Q; Li, ... Dobritsa AP, Samadpour M. (2016). "Transfer of eleven species of the genus Burkholderia to the genus Paraburkholderia and ... to accommodate twelve species of the genera Burkholderia and Paraburkholderia". Int J Syst Evol Microbiol. 66 (8): 2836-2846. ... WJ (2013-03-25). "Burkholderia zhejiangensis sp. nov., a methyl-parathion-degrading bacterium isolated from a wastewater- ...
Yoo, SH; Kim, BY; Weon, HY; Kwon, SW; Go, SJ; Stackebrandt, E (2013-03-25). "Burkholderia soli sp. nov., isolated from soil ... 2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
"Burkholderia bryophila sp. nov. and Burkholderia megapolitana sp. nov., moss-associated species with antifungal and plant- ... 2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ... ". "Burkholderia bryophila". Ezbiocloud.net. Vandamme, Peter; Opelt, Katja; Knöchel, Nadine; Berg, Christian; Schönmann, Susan ...
"Genus Burkholderia". List of Prokaryotic Names with Standing in Nomenclature. Retrieved 15 November 2016. CS1 maint: ... discouraged parameter (link) Yabuuchi, E; Kosako, Y; Yano, I; Hotta, H; Nishiuchi, Y (1995). "Transfer of two Burkholderia and ...
"Genus Burkholderia". List of Prokaryotic Names with Standing in Nomenclature. Retrieved 15 November 2016. Dobritsa AP, ... "Nomenclature: Burkholderia grimmiae Tian et al. 2013". EzBIOCLOUD. Retrieved 15 November 2016. v t e. ... to accommodate twelve species of the genera Burkholderia and Paraburkholderia". Int J Syst Evol Microbiol. 66 (8): 2836-2846. ... "Burkholderia grimmiae sp. nov., isolated from a xerophilous moss (Grimmia montana)". Int J Syst Evol Microbiol. 63 (Pt 6): 2108 ...
"Transfer of 13 species of the genus Burkholderia to the genus Caballeronia and reclassification of Burkholderia jirisanensis as ... 2017). "Burkholderia". Frontiers in Microbiology. 8: 1679. doi:10.3389/fmicb.2017.01679. PMC 5592201. PMID 28932212. Uroz S, ... to accommodate twelve species of the genera Burkholderia and Paraburkholderia". International Journal of Systematic and ... "Transfer of eleven species of the genus Burkholderia to the genus Paraburkholderia and proposal of Caballeronia gen. nov. ...
"Burkholderia caryophylli". EPPO Bulletin. 36 (1): 95-98. Jun 2006. doi:10.1111/j.1365-2338.2006.00918.x. Alipour, Yadolah. "A ... "Data Sheets on Quarantine Pests-Burkholderia caryophylli" (PDF). CABI and EPPO for the EU. Archived from the original (PDF) on ... "Scientific Opinion on the risk to plant health posed by Burkholderia caryophylli for the EU territory with the identification ... Burkholderia caryophylli) In Carnation ( Dianthus caryophyllus) Using An SSR-Based Genetic Linkage Map". Molecular Breeding. 30 ...
Del Prete S, Nocentini A, Supuran CT, Capasso C (December 2020). "Burkholderia territorii". Journal of Enzyme Inhibition and ...
"Ornibactin production and transport properties in strains of Burkholderia vietnamiensis and Burkholderia cepacia (formerly ... Coenye T, Vandamme P, Govan JR, LiPuma JJ (October 2001). "Taxonomy and identification of the Burkholderia cepacia complex". ... LiPuma JJ (September 1998). "Burkholderia cepacia. Management issues and new insights". Clinics in Chest Medicine. 19 (3): 473- ... Ornibactin is produced by Burkholderia cenocepacia under iron-deficient conditions. B. cenocepacia is known to ...
"Burkholderia denitrificans". Ezbiocloud.net. Archived from the original on 2013-12-15. v t e. ... 2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... PMID 25566316.CS1 maint: uses authors parameter (link) "Burkholderia denitrificans Taxon Passport - StrainInfo". "J.P. Euzéby: ... "Burkholderia denitrificans sp. nov., isolated from the soil of Dokdo Island, Korea". Journal of Microbiology. 50 (5): 855-9. ...
"Genus Burkholderia". List of Prokaryotic Names with Standing in Nomenclature. Retrieved 15 November 2016. Kim, HB; Park, MJ; ... 2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... PMID 25566316.CS1 maint: uses authors parameter (link) "Strain Passport NBRC 100965 Burkholderia ginsengisoli". StrainInfo. ... Yang, HC; An, DS; Jin, HZ; Yang, DC (2006). "Burkholderia ginsengisoli sp. nov., a beta-glucosidase-producing bacterium ...
G. sporarum and Burkholderia sp. have been identified to be β-proteobacteria, a gram-negative class of bacteria, and N. ... Burkholderia sp. in R. microsporus have been found to produce rhizoxin, an inhibitor of mitosis originally thought to be ... The production of rhizoxin by Burkholderia sp. leading to the death of plant cells allows R. microsporus to gain greater access ... R. microsporus relies on its bacterial partner of the Burkholderia sp. for the pathogenic toxin. Previous efforts to control ...
Pseudomonas cepacia, a.k.a. Burkholderia cepacia. Nocardia. Fungi Aspergillus species. Aspergillus has a propensity to cause ...
2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... "Burkholderia oxyphila sp. nov., a bacterium isolated from acidic forest soil that catabolizes (+)-catechin and its putative ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
Type strain of Burkholderia insulsa at BacDive - the Bacterial Diversity Metadatabase v t e. ... Dobritsa AP, Samadpour M. (2016). "Transfer of eleven species of the genus Burkholderia to the genus Paraburkholderia and ... to accommodate twelve species of the genera Burkholderia and Paraburkholderia". Int J Syst Evol Microbiol. 66 (8): 2836-2846. ... arsenic-tolerant and aerobic bacterium from the genus of Burkholderia which has been isolated from the Ambitle Island on Papua ...
Typically, each species of Burkholderia has 3-5 homologous tsRNAs. Experiments with four species of the Burkholderia lineage ... Sass AM, De Waele S, Daled S, Devreese B, Deforce D, Van Nieuwerburgh F, Coenye T (October 2019). "Burkholderia cenocepacia ... Broadly, it is suggested that tsRNAs regulate carbohydrate and amino acid metabolism in Burkholderia. They are more highly ... Sass A, Kiekens S, Coenye T (November 2017). "Identification of small RNAs abundant in Burkholderia cenocepacia biofilms reveal ...
Type strain of Burkholderia susongensis at BacDive-the Bacterial Diversity Metadatabase v t e. ... Dobritsa AP, Samadpour M. (2016). "Transfer of eleven species of the genus Burkholderia to the genus Paraburkholderia and ... to accommodate twelve species of the genera Burkholderia and Paraburkholderia". Int J Syst Evol Microbiol. 66 (8): 2836-2846. ... "Burkholderia susongensis sp. nov., a mineral-weathering bacterium isolated from weathered rock surface". International Journal ...
2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... "Burkholderia ferrariae sp. nov., isolated from an iron ore in Brazil" (PDF). International Journal of Systematic and ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
"Burkholderia tuberum sp. nov. and Burkholderia phymatum sp. nov., nodulate the roots of tropical legumes". Systematic and ... 2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... Jun 2014). "Complete Genome sequence of Burkholderia phymatum STM815T, a broad host range and efficient nitrogen-fixing ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... "Burkholderia bannensis sp. nov., an acid-neutralizing bacterium isolated from torpedo grass (Panicum repens) growing in highly ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... 56 (Pt 8): 1931-7. doi:10.1099/ijs.0.64362-0. PMID 16902033.CS1 maint: multiple names: authors list (link) "Burkholderia ... "Burkholderia silvatlantica sp. nov., a diazotrophic bacterium associated with sugar cane and maize". Int J Syst Evol Microbiol ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
Sep 2012). "Burkholderia symbiotica sp. nov., isolated from root nodules of Mimosa spp. native to north-east Brazil". Int J ... 2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
PMID 25566316.CS1 maint: uses authors parameter (link) Straininfo of Burkholderia rhynchosiae LSPN lpsn.dsmz.de De Meyer, S. E ... 2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... Cnockaert, M.; Ardley, J. K.; Trengove, R. D.; Garau, G.; Howieson, J. G.; Vandamme, P. (2013). "Burkholderia rhynchosiae sp. ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
"Burkholderia tuberum sp. nov. and Burkholderia phymatum sp. nov., nodulate the roots of tropical legumes". Systematic and ... 2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... "Burkholderia sabiae sp. nov., isolated from root nodules of Mimosa caesalpiniifolia". Int. J. Syst. Evol. Microbiol. 58 (Pt 9 ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
was reckoned to be a new species in the genus, and the name Burkholderia kururiensis was proposed. The type strain is KP23T (= ... 2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... "Burkholderia kururiensis sp. nov., a trichloroethylene (TCE)-degrading bacterium isolated from an aquifer polluted with TCE". ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
nov., a New Species Related to Burkholderia thailandensis and the Fifth Member of the Burkholderia pseudomallei Complex". Appl ... Burkholderia humptydooensis has been proposed as its taxonomic name. From September 2009 to December 2009, the numbers station ... A bacterial species of the genus Burkholderia was first isolated during routine screening of a water well in Humpty Doo. ...
"Burkholderia humisilvae sp. nov., Burkholderia solisilvae sp. nov. and Burkholderia rhizosphaerae sp. nov., isolated from ... Dobritsa AP, Samadpour M. (2016). "Transfer of eleven species of the genus Burkholderia to the genus Paraburkholderia and ... to accommodate twelve species of the genera Burkholderia and Paraburkholderia". Int J Syst Evol Microbiol. 66 (8): 2836-2846. ...
2014). "Molecular signatures and phylogenomic analysis of the genus Burkholderia: Proposal for division of this genus into the ... "Burkholderia sartisoli sp. nov., isolated from a polycyclic aromatic hydrocarbon-contaminated soil" (PDF). Int. J. Syst. Evol. ... emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental ...
October 2005). "Comparison of Ashdowns medium, Burkholderia cepacia medium, and Burkholderia pseudomallei selective agar for ... 2011). "Rapid identification of Burkholderia pseudomallei and Burkholderia mallei by fluorescence in situ hybridization (FISH) ... Pathema Burkholderia resource "Burkholderia pseudomallei". NCBI Taxonomy Browser. 28450. ... Burkholderia thailandensis) and arabinose-negative Burkholderia pseudomallei". Microbiology and immunology. 43 (7): 625-30. doi ...
Summarize the basic epidemiology and ecology of Burkholderia spp.. *List important aspects of biosafety in working with ... Use sentinel laboratory protocols to Rule Out or Refer isolates for the identification of Burkholderia spp. ... This course provides clinical laboratory scientists with information about the laboratory identification of Burkholderia spp. ... Outline the role of the LRN sentinel laboratory in the detection of Burkholderia spp. ...
Burkholderia alpina Burkholderia ambifaria Burkholderia anthina Burkholderia arboris Burkholderia cenocepacia Burkholderia ... Burkholderia dolosa Burkholderia gladioli Burkholderia glumae Burkholderia humptydooensis Burkholderia lata Burkholderia latens ... Burkholderia mallei Burkholderia metallica Burkholderia multivorans Burkholderia oklahomensis Burkholderia plantarii ... Burkholderia pseudomallei Burkholderia pseudomultivorans Burkholderia puraquae Burkholderia pyrrocinia Burkholderia seminalis ...
nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. nov., Burkholderia seminalis sp. nov. and Burkholderia metallica ... Burkholderia arboris is a Gram-negative, aerobic, non-spore-forming bacterium of the genus Burkholderia and the family ... doi:10.1099/ijs.0.65634-0. PMID 18599699.[permanent dead link] "Burkholderia arboris". Type strain of Burkholderia arboris at ... B. arboris belongs to the Burkholderia cepacia complex. "J.P. Euzéby: List of bacterial names with standing in nomenclature". " ...
Burkholderia cepacia [burk-hōld-er-ee-uh si-pay-shee-uh] (also called B. cepacia) is the name for a group or "complex" of ... For more information see the Notice to Readers: Manufacturers Recall of Nasal Spray Contaminated with Burkholderia cepacia ... For more information see the Notice to Readers: Nosocomial Burkholderia cepacia Infections Associated with Exposure to ...
p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc.,/p> ,p>,a href="/manual/evidences">More…,/a>,/p> ...
Your basket is currently empty. i ,p>When browsing through different UniProt proteins, you can use the basket to save them, so that you can back to find or analyse them later.,p>,a href=/help/basket target=_top>More...,/a>,/p> ...
The multifarious, multireplicon Burkholderia cepacia complex.. Mahenthiralingam E1, Urban TA, Goldberg JB. ... The Burkholderia cepacia complex (Bcc) is a collection of genetically distinct but phenotypically similar bacteria that are ...
Burkholderia pseudomallei: Brief Summary provided by wikipedia EN Burkholderia pseudomallei (also known as Pseudomonas ... 2011). Rapid identification of Burkholderia pseudomallei and Burkholderia mallei by fluorescence in situ hybridization (FISH) ... October 2005). Comparison of Ashdowns medium, Burkholderia cepacia medium, and Burkholderia pseudomallei selective agar for ... Burkholderia thailandensis) and arabinose-negative Burkholderia pseudomallei. Microbiology and Immunology. 43 (7): 625-30. doi ...
Detection of Pseudomonas (Burkholderia) cepacia using PCR.. Campbell PW 3rd1, Phillips JA 3rd, Heidecker GJ, Krishnamani MR, ...
Burkholderia cepacia,/i, complex infections in cystic fibrosis (CF) has recently been ascribed to differences in the virulence ... Cepacia-Like Syndrome Caused by Burkholderia mutivorans. George Zahariadis. ,1 Michelle H Levy. ,2 and Jane L Burns3. 1 ... Cepacia-Like Syndrome Caused by Burkholderia mutivorans,. Canadian Journal of Infectious Diseases and Medical Microbiology,. ... The variable severity of Burkholderia cepacia complex infections in cystic fibrosis (CF) has recently been ascribed to ...
Organism: BURKHOLDERIA MALLEI NCTC 10229 18. BURM9_1_PE1013 (BURM9_1.PE1013). Organism: BURKHOLDERIA MALLEI NCTC 10229 19. ... Organism: BURKHOLDERIA MALLEI NCTC 10229 If you have problems or comments... Back to PBIL home page ... Organism: BURKHOLDERIA MALLEI NCTC 10229 2. BURM9_1_PE10 RecName: Full=UvrABC system protein B; (BURM9_1.PE10). Keywords: ... Organism: BURKHOLDERIA MALLEI NCTC 10229 16. BURM9_1_PE1011 SubName: Full=Rhs element Vgr protein; (BURM9_1.PE1011). Keywords: ...
Burkholderia comprises more than 60 species of environmental, clinical, and agro-biotechnological relevance. Previous ... nov., Burkholderia diffusa sp. nov., Burkholderia arboris sp. nov., Burkholderia seminalis sp. nov. and Burkholderia metallica ... Transfer of Pseudomonas plantarii and Pseudomonas glumae to Burkholderia as Burkholderia spp. and description of Burkholderia ... Burkholderia nifH Gene Acetylene Reduction Activity Melioidosis Burkholderia Species These keywords were added by machine and ...
... Taksaon Duangurai,1,2 Nitaya Indrawattana,1 and ... Burkholderia pseudomallei is a Gram-negative bacterium that causes melioidosis, which can be fatal in humans. Melioidosis is ...
Genomic DNA from Burkholderia cenocepacia strain LMG 16656 TypeStrain=False Application: ... Burkholderia cepacia (Palleroni and Holmes) Yabuuchi et al. Strain Designations Genomic DNA from Burkholderia cenocepacia ... Burkholderia cenocepacia (ATCC® BAA-245D-5™) Strain Designations: Genomic DNA from Burkholderia cenocepacia strain LMG 16656 [ ... Burkholderia cenocepacia ATCC® BAA-245D-5™ dried Total DNA: At least 5 µg in 1X TE buffer ...
Retrieved from "https://species.wikimedia.org/w/index.php?title=Burkholderia_virus_Bcepmigl&oldid=6015206" ...
NAME: Burkholderia (Pseudomonas) mallei SYNONYM OR CROSS REFERENCE: Glanders, Malleomyces mallei, Farcy, Malleus; formerly ...
Control of Cotton Seedling Damping-off in the Field by Burkholderia (Pseudomonas) cepacia. K. Zaki, I. J. Misaghi, and A. ... Mobilization, Cloning, and Sequence Determination of a Plasmid-Encoded Polygalacturonase from a Phytopathogenic Burkholderia ( ... Related articles on Burkholderia cepacia from APS Journals. ...
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei. Matthew T. G. Holden, Richard W. Titball, ... Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei. Matthew T. G. Holden, Richard W. Titball, ... Burkholderia pseudomallei is a recognized biothreat agent and the causative agent of melioidosis. This Gram-negative bacterium ... Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei. Matthew T. G. Holden, Richard W. Titball, ...
Cross-Species Comparison of the Burkholderia pseudomallei, Burkholderia thailandensis, and Burkholderia mallei Quorum-Sensing ... Targeted Mutagenesis of Burkholderia thailandensis and Burkholderia pseudomallei through Natural Transformation of PCR ... Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei. Matthew T. G. Holden, Richard W. Titball, ... Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei. Matthew T. G. Holden, Richard W. Titball, ...
Burkholderia ubonensis Meropenem Resistance: Insights into Distinct Properties of Class A β-Lactamases in Burkholderia cepacia ... Mechanisms of Resistance to Folate Pathway Inhibitors in Burkholderia pseudomallei: Deviation from the Norm Burkholderia ... Burkholderia pseudomallei causes melioidosis, a tropical disease that is highly fatal if not properly treated. Our data show ... The Complex Quorum Sensing Circuitry of Burkholderia thailandensis Is Both Hierarchically and Homeostatically Organized Servane ...
Burkholderia vietnamiensis, Burkholderia multivorans, Burkholderia stabilis and Burkholderia cepacia genomovars I and III. J ... Proposal to accommodate Burkholderia cepacia genomovar VI as Burkholderia dolosa sp. nov. Int J Syst Evol Microbiol 54:689-691. ... Burkholderia cepacia: Friend or Foe?. Parke, J.L. 2000. Burkholderia cepacia: Friend or Foe? The Plant Health Instructor. DOI: ... Burkholderia cepacia genomovar VI, a new member of the Burkholderia cepacia complex isolated from cystic fibrosis patients. Int ...
Burkholderia (Genus); Burkholderia cepacia complex (Species Group); Burkholderia contaminans (Species) ... Burkholderia contaminans belongs to a group of closely related bacteria called the "Burkholderia cepacia complex" ("Bcc"), ... Burkholderia contaminans, like other members of the Burkholderia cepacia complex, are considered to be opportunistic pathogens ... "Taxon K, a complex within the Burkholderia cepacia complex, comprises at least two novel "species, Burkholderia contaminans sp ...
Burkholderia pseudomallei Description and significance. Burkholderia pseudomallei is a gram-negative bacterium with dimensions ... Burkholderia pseudomallei is a human and animal pathogen and is the cause of melioidosis, which is a disease native to ... Burkholderia pseudomallei is significant in its role of causing a disease known as melioidosis, which currently doesnt have a ... Burkholderia pseudomallei is thought to have biological warfare potential and its virulence is made evident by being listed as ...
Burkholderia Pseudomallei Genome Project. Burkholderia pseudomallei, the causative agent of the infectious disease melioidosis ...
Glycolysis / Gluconeogenesis - Burkholderia lata [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show ...
Burkholderia thailandensis E264. Mutation(s): 0 Gene Names: BTH_I1058, tpiA. EC: 5.3.1.1. ... Find proteins for Q2SZN7 (Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)) ... The genus Burkholderia includes pathogenic gram-negative bacteria that cause melioidosis, glanders, and pulmonary infections of ... The genus Burkholderia includes pathogenic gram-negative bacteria that cause melioidosis, glanders, and pulmonary infections of ...
Genomic DNA from Burkholderia cepacia strain 249 TypeStrain=False Application: ... Genomic DNA from Burkholderia cepacia strain 249 [ATCC® 17616™] Biosafety Level 1 Biosafety classification is based on U.S. ... Burkholderia cepacia (Palleroni and Holmes) Yabuuchi et al. (ATCC® 17616D-5™) Strain Designations: Genomic DNA from ... Nucleotide (GenBank) : AY741333 Burkholderia cepacia strain ATCC 17616 16S ribosomal RNA gene, partial sequence ...
  • Burkholderia pseudomallei (also known as Pseudomonas pseudomallei) is a Gram-negative, bipolar, aerobic, motile rod-shaped bacterium. (wikipedia.org)
  • Even when the isolate is recognised to be significant, commonly used identification systems may misidentify the organism as Chromobacterium violaceum or other nonfermenting, Gram-negative bacilli such as Burkholderia cepacia or Pseudomonas aeruginosa. (wikipedia.org)
  • and Burkholderia cepacia, an important pathogen of pulmonary infections in people with cystic fibrosis (CF). The Burkholderia (previously part of Pseudomonas) genus name refers to a group of virtually ubiquitous Gram-negative, obligately aerobic, rod-shaped bacteria that are motile by means of single or multiple polar flagella, with the exception of Burkholderia mallei, which is nonmotile. (wikipedia.org)
  • Detection of Pseudomonas (Burkholderia) cepacia using PCR. (nih.gov)
  • Mobilization, Cloning, and Sequence Determination of a Plasmid-Encoded Polygalacturonase from a Phytopathogenic Burkholderia ( Pseudomonas ) cepacia . (apsnet.org)
  • Control of Cotton Seedling Damping-off in the Field by Burkholderia ( Pseudomonas ) cepacia . (apsnet.org)
  • Formerly known as Pseudomonas cepacia, the bacterium now known as Burkholderia cepacia, was first described in 1950 as the cause of sour skin of onions by Cornell University plant pathologist Walter Burkholder (1). (apsnet.org)
  • Burns JL, Jonas M, Chi EY, Clark DK, Berger A, Griffith A (1996) Invasion of respiratory epithelial cells by Burkholderia ( Pseudomonas ) cepacia . (springer.com)
  • Burkholderia (formerly Pseudomonas ) cepacia is an opportunistic pathogen in immunocompromised patients, particularly those with cystic fibrosis (CF) or chronic granulomatous disease (reviewed in references 8 and 9 ). (asm.org)
  • To investigate an outbreak of Burkholderia (formerly ( Pseudomonas ) cepacia respiratory tract colonization and infection in mechanically ventilated patients. (annals.org)
  • The emergence of a highly transmissible lineage of cbl+ Pseudomonas (Burkholderia) cepacia causing CF centre epidemics in North America and Britain. (umass.edu)
  • The rapid increase in Pseudomonas (Burkholderia) cepacia infection in cystic fibrosis (CF) patients suggests epidemic transmission, but the degree of transmissibility remains controversial as conflicting conclusions have been drawn from studies at different CF centres. (umass.edu)
  • Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia. (asm.org)
  • Genetic diversity among isolates of the bacterial plant pathogen Burkholderia solanacearum (synonym Pseudomonas solanacearum) race 3 biovar II of Kenya was determined by PCR with repetitive sequences (ERIC and BOX repetitive primer sets) and pulsed-field gel electrophoresis of genomic DNA digested by rare-cutting restriction endonucleases (RC-PFGE). (www.gov.uk)
  • Although evidence-based guidelines exist for treating respiratory exacerbations involving Pseudomonas aeruginosa, these cannot be extended to Burkholderia cepacia complex infections. (cochrane.org)
  • Comparative analysis highlights the role that horizontal gene acquisition has played in the evolution of the genome and clarifies the genetic relationship of B. pseudomallei with Burkholderia mallei , the genome of which is described in an accompanying manuscript ( 10 ). (pnas.org)
  • Abstract Burkholderia pseudomallei and Burkholderia mallei are highly pathogenic Gram-negative bacteria and the causative agents of melioidosis and glanders, respectively. (sbir.gov)
  • Burkholderia pseudomallei ( Bp ) and Burkholderia mallei ( Bm ), the etiologic agents of melioidosis and glanders, respectively, cause severe disease in both humans and animals. (nature.com)
  • The genetically related Burkholderia mallei ( Bm ), the causative agent of glanders, primarily infects solipeds but can also lead to fatal infections in humans if left untreated 4 . (nature.com)
  • Burkholderia mallei , the etiologic agent of glanders, are Category B select agents with biothreat potential, and yet effective therapeutic treatments are lacking. (mdpi.com)
  • Burkholderia thailandensis is a model organism for human pathogens Burkholderia mallei and Burkholderia pseudomallei . (frontiersin.org)
  • Burkholderia pseudomallei and Burkholderia mallei are closely related Gram-negative bacteria responsible for the infectious diseases melioidosis and glanders, respectively. (frontiersin.org)
  • To date, the best characterized of the predicted ATs of B. pseudomallei and B. mallei is BimA, a predicted trimeric AT mediating actin-based motility which varies in sequence and mode of action between Burkholderia species. (frontiersin.org)
  • Burkholderia mallei is closely related to B. pseudomallei and is the etiological agent of Glanders, an infectious equine disease that can be transmitted to humans. (frontiersin.org)
  • Culture results from skin lesions, abscesses, and respiratory aspirates will grow the gram-negative rod Burkholderia mallei. (oncologynurseadvisor.com)
  • The most recent case of glanders (in 2000) was diagnosed in a laboratory worker that was working with the Burkholderia mallei bacterium. (oncologynurseadvisor.com)
  • The use of Burkholderia mallei as a biological weapon of mass destruction is a concern. (oncologynurseadvisor.com)
  • Glanders is caused by the zoonotic gram-negative nonencapsulated nonmotile aerobic bacterium, Burkholderia mallei. (oncologynurseadvisor.com)
  • The complete genome sequence of Burkholderia mallei ATCC 23344 provides insight into this highly infectious bacterium's pathogenicity and evolutionary history. (umd.edu)
  • Possible dissemination of melioidosis by historical trading routes is supported by links to strains from Southeast Asia, China, and Africa and the presence of the Burkholderia mallei allele of the bimA gene. (ajtmh.org)
  • Burkholderia thailandensis is a member of a closely related cluster of three species, including the animal pathogens Burkholderia mallei and Burkholderia pseudomallei. (ku.edu)
  • Burkholderia pseudomallei and B. mallei, the causative agents of melioidosis and glanders, respectively, are designated category B biothreat agents. (unboundmedicine.com)
  • Glanders is caused by infection with the bacterium Burkholderia mallei , and melioidosis is caused by Burkholderia pseudomallei . (centerforhealthsecurity.org)
  • Burkholderia pseudomallei is a Gram-negative bacterium that causes melioidosis, which can be fatal in humans. (hindawi.com)
  • Burkholderia pseudomallei is a recognized biothreat agent and the causative agent of melioidosis. (pnas.org)
  • Melioidosis is a bacterial infection caused by Burkholderia pseudomallei , an environmental Gram-negative saprophyte present in wet soil and rice paddies in endemic areas ( 1 - 3 ). (pnas.org)
  • Burkholderia pseudomallei causes melioidosis, a tropical disease that is highly fatal if not properly treated. (asm.org)
  • Burkholderia pseudomallei causes melioidosis, a tropical disease that is difficult to treat. (asm.org)
  • Burkholderia pseudomallei is significant in its role of causing a disease known as melioidosis, which currently doesn't have a vaccine. (kenyon.edu)
  • Burkholderia pseudomallei is a human and animal pathogen and is the cause of melioidosis, which is a disease native to Southeast Asia and northern Australia. (kenyon.edu)
  • Burkholderia pseudomallei , the causative agent of the infectious disease melioidosis, is a CDC Category B biological threat agent, and occurs as a soil organism in Southeast Asia and Northern Australia. (jcvi.org)
  • The genus Burkholderia includes pathogenic gram-negative bacteria that cause melioidosis, glanders, and pulmonary infections of patients with cancer and cystic fibrosis. (rcsb.org)
  • ABSTRACT: BACKGROUND: Burkholderia pseudomallei is a soil-dwelling saprophyte and the cause of melioidosis. (jcvi.org)
  • In this study, we describe BpsIR, a LuxIR homolog in Burkholderia pseudomallei , a gram-negative soil bacillus and etiologic agent of human and animal melioidosis. (asm.org)
  • Cutaneous melioidosis and necrotizing fasciitis caused by Burkholderia pseudomallei. (thefreelibrary.com)
  • Melioidosis is a disease caused by a gram-negative bacterium, Burkholderia pseudomallei. (thefreelibrary.com)
  • Burkholderia pseudomallei , the etiological agent of melioidosis, is a Gram-negative bacterium with additional concern as a biothreat pathogen. (asm.org)
  • Limited experience and a lack of validated diagnostic reagents make Burkholderia pseudomallei , the cause of melioidosis, difficult to recognize in the diagnostic microbiology laboratory. (asm.org)
  • Burkholderia pseudomallei , the cause of melioidosis, can be difficult to reliably identify in the clinical microbiology laboratory. (asm.org)
  • The Burkholderia pseudomallei Infections (Infectious Disease) pipeline guide also reviews of key players involved in therapeutic development for Burkholderia pseudomallei Infections (Melioidosis) and features dormant and discontinued projects. (reportbuyer.com)
  • IMPORTANCE The saprophyte Burkholderia thailandensis is a close relative of the pathogenic bacterium Burkholderia pseudomallei, the causative agent of melioidosis, which is contracted from its environmental reservoir. (ku.edu)
  • Burkholderia pseudomallei causes the potentially fatal disease melioidosis. (asm.org)
  • Infection with the gram-negative bacterium Burkholderia pseudomallei can result in a life-threatening disease known as melioidosis. (health.mil)
  • Melioidosis is a potentially lifethreatening disease caused by the gram-negative bacterium Burkholderia pseudomallei . (health.mil)
  • Glanders and melioidosis are infectious diseases caused by species of the bacterial genus Burkholderia . (centerforhealthsecurity.org)
  • In Burkholderia species, certain antibiotics such as trimethoprim has been shown to induce and upregulate a large amount of the metabolome, inducing over 100 silent secondary metabolite gene clusters in Burkholderia thailandensis. (wikipedia.org)
  • Research focused on interbacterial signaling using Burkholderia has shown that contact-dependent growth inhibition plays a significant role in mediating cell to cell communication specifically in B. thailandensis. (wikipedia.org)
  • Burkholderia thailandensis sp. (nih.gov)
  • In this study, a comprehensive 16S rDNA-based phylogenetic analysis further supports the existence of this newly described Burkholderia species for which the name Burkholderia thailandensis sp. (nih.gov)
  • Mice immunized with LPS from Bp , and from the non-pathogenic Burkholderia thailandensis ( Bt ), developed high-titer immunoglobulin G (IgG) responses and were partially protected against lethal challenges of Bp 29 , 30 . (nature.com)
  • during infection, we performed a RNA interference (RNAi) screen of the human kinome and identified 35 host kinases that facilitated Burkholderia thailandensis intracellular survival in human monocytic THP-1 cells. (osti.gov)
  • We focused on the role of the novel protein kinase C isoform, PKC-η, in Burkholderia infection and characterized PKC-η/MARCKS signaling as a key event that promotes the survival of unopsonized B. thailandensis CDC2721121 within host cells. (osti.gov)
  • In this study, we characterized Burkholderia thailandensis biofilm development under flow conditions and sought to determine whether QS contributes to this process. (ku.edu)
  • Since most bacteria in the environment reside in biofilms, B. thailandensis is an ideal model organism for investigating questions in Burkholderia physiology. (ku.edu)
  • The bacterium Burkholderia thailandensis produces an arsenal of secondary metabolites that have diverse structures and roles in the ecology of this soil-dwelling bacterium. (asm.org)
  • AY278465 Burkholderia cenocepacia strain LMG 16656 outer membrane lipoprotein precursor (opcL) gene, partial cds. (atcc.org)
  • Burkholderia cenocepacia is a soil-dwelling Gram-negative Betaproteobacterium with an important role as opportunistic pathogen in humans. (nih.gov)
  • The opportunistic pathogen Burkholderia cenocepacia uses a chemical signal process called quorum sensing (QS) to produce virulence factors. (asm.org)
  • Agnoli K, Lowe CA, Farmer KL, Husnain SI, Thomas MS (2006) The ornibactin biosynthesis and transport genes of Burkholderia cenocepacia are regulated by an extracytoplasmic function s factor which is a part of the Fur regulon. (springer.com)
  • Bernier SP, Sokol PA (2005) Use of suppression-subtractive hybridization to identify genes in the Burkholderia cepacia complex that are unique to Burkholderia cenocepacia . (springer.com)
  • Bernier SP, Nguyen DT, Sokol PA (2008) A LysR-type transcriptional regulator in Burkholderia cenocepacia influences colony morphology and virulence. (springer.com)
  • Bylund J, Burgess LA, Cescutti P, Ernst RK, Speert D (2006) Exopolysaccharides from Burkholderia cenocepacia inhibit neutrophil chemotaxis and scavenge reactive oxygen species. (springer.com)
  • An antibiotic efflux gene cluster that confers resistance to chloramphenicol, trimethoprim, and ciprofloxacin has been identified in Burkholderia cenocepacia (genomovar III), an important cystic fibrosis pathogen. (jci.org)
  • Here, we present a genome-wide view of the molecular mutation spectrum in Burkholderia cenocepacia , a clinically relevant pathogen with high %GC content and multiple chromosomes. (genetics.org)
  • Effects of extended storage of chlorhexidine gluconate and benzalkonium chloride solutions on the viability of Burkholderia cenocepacia. (eurosurveillance.org)
  • Several transmissible Burkholderia cenocepacia strains that infect multiple cystic fibrosis patients contain a genomic island designated as the c eno c epacia i sland (cci). (asm.org)
  • Until recently, the genus Burkholderia was inclusive of all Paraburkholderia species. (wikipedia.org)
  • However, the genus Paraburkholderia is phylogenetically distinct, and can be distinguished from all Burkholderia species on the basis of molecular signatures that are uniquely found for each genus. (wikipedia.org)
  • Burkholderia species form a monophyletic group within the Burkholderiales order of the Betaproteobacteria. (wikipedia.org)
  • These indels represent exclusive common ancestry shared among all Burkholderia species. (wikipedia.org)
  • Recently, research in Burkholderia species has investigated a range of topics and characteristics including metabolomic response to antibiotics, contact-dependent interactions between bacterial communities, and genomic potential to yield beneficial products. (wikipedia.org)
  • It has been shown that closely related cystic fibrosis-associated Burkholderia species respond to trimethoprim with differing levels of expression of various secondary metabolites, highlighting the personalized nature of metabolomics in related bacterial strains. (wikipedia.org)
  • Burkholderia species have been shown to be a potential source of beneficial products such as antimicrobials and biosurfactants. (wikipedia.org)
  • nov., novel species within the Burkholderia cepacia complex" (PDF). (wikipedia.org)
  • The Burkholderia cepacia complex (Bcc) is a collection of genetically distinct but phenotypically similar bacteria that are divided into at least nine species. (nih.gov)
  • Burkholderia comprises more than 60 species of environmental, clinical, and agro-biotechnological relevance. (springer.com)
  • Previous phylogenetic analyses of 16S rRNA, recA , gyrB , rpoB , and acdS gene sequences as well as genome sequence comparisons of different Burkholderia species have revealed two major species clusters. (springer.com)
  • However, it will be necessary to analyze the full set of Burkholderia species and explore whether enough phenotypic features exist among the different clusters to propose that these groups should be considered separate genera. (springer.com)
  • The Burkholderia cepacia complex (Bcc) is a group of at least 9 closely related species (often called "genomovars") that is currently attracting considerable attention for their extraordinary versatility as plant pathogens, saprophytes, biocontrol agents, bioremediation agents, and human pathogens. (apsnet.org)
  • Burkholderia contaminans belongs to a group of closely related bacteria called the " Burkholderia cepacia complex" ("Bcc"), specifically within a subgroup of Bcc known as "Taxon K" or "Group K." Cells of this species are non-sporulating, aerobic, and Gram-negative rods that form moist, metallic colonies when plated. (kenyon.edu)
  • The presence of a Burkholderia pseudomallei-like species based upon the significant genotypic and phenotypic dissimilarities exhibited between these organisms and true B. pseudomallei strains has been reported previously. (nih.gov)
  • The Burkholderia cepacia complex (Bcc) is a group of closely related gram-negative bacteria comprising at least 9 species (1). (thefreelibrary.com)
  • The Burkholderia cepacia complex (Bcc) is a group of 17 closely related species of the β-proteobacteria subdivision that emerged in the 1980s as important human pathogens, especially to patients suffering from cystic fibrosis. (springer.com)
  • The name B. cepacia will relate only to B. cepacia genomovar I. Strains resembling B. cepacia may belong to the B. cepacia complex, to other Burkholderia species (for instance, Burkholderia gladioli ), or to species from other genera (for instance, Ralstonia pickettii ) that share some phenotypic or genotypic similarities with the B. cepacia complex. (asm.org)
  • Burkholderia comprises species that are significant biothreat agents and common contaminants of pharmaceutical production facilities. (asm.org)
  • The most commonly identified Bcc species in newly colonised patients, Burkholderia multivorans , continues to be acquired from the environment. (mdpi.com)
  • We compared three methods of confirming the identity of presumptive B. pseudomallei strains using a collection of Burkholderia species drawn from diverse geographic, clinical, and environmental sources. (asm.org)
  • Practical difficulties for the diagnostic laboratory include the presence of closely related Burkholderia species in specimens from nonsterile sites and atypical colony morphology of some B. pseudomallei strains ( 4 ). (asm.org)
  • Chronic infection with Burkholderia cepacia complex species remains a significant problem for clinicians treating people with cystic fibrosis. (cochrane.org)
  • No studies looking at the eradication of Burkholderia cepacia complex species were identified. (cochrane.org)
  • Over the past 20 years a group of closely related Burkholderia species termed the B. cepacia complex (Bcc) have emerged as opportunistic pathogens of particular importance in people with cystic fibrosis (CF) and chronic granulomatous disease ( 31 , 33 ). (asm.org)
  • Burkholderia cepacia ( B. cepacia ) complex is composed of 20 phylogenetically closely related bacterial species. (elsevier.es)
  • Infections dominated by organisms of the Burkholderia cepacia complex, a group of at least 18 closely-related species of gram-negative bacteria, are particularly difficult to treat. (cochrane.org)
  • Nevertheless, infection is spread through ingestion or contact of bacteria onto open skin wounds or through the inhalation of the aerosolized Burkholderia pseudomallei . (kenyon.edu)
  • We report a case of biliary tract infection caused by a strain of Burkholderia contaminans, a member of the Burkholderia cepacia complex. (biomedsearch.com)
  • Nosocomial outbreak of Burkholderia pickettii infection due to a manufactured intravenous product used in three hospitals. (thefreedictionary.com)
  • He investigates the role and function of pathogen-recognition-receptors and innate immunity in sepsis, with a special interest Burkholderia pseudomallei and Salmonella typhi infection and the role of diabetes as well as the gut microbiota during sepsis. (omicsonline.org)
  • Infection with Burkholderia cepacia due to social contact is well described in patients with cystic fibrosis. (bmj.com)
  • Pulmonary infection with Burkholderia cepacia complex (BCC) in patients with CF is often associated with a more rapid decline in lung function. (clinicaltrials.gov)
  • As a result, identification of host kinases that are targeted by Burkholderia during infection provides valuable molecular insights in understanding Burkholderia pathogenesis, and ultimately, in designing effective host-targeted therapies against infectious disease caused by intracellular pathogens. (osti.gov)
  • Burkholderia infection is caused by the Burkholderia cepacia bacteria . (naturalpedia.com)
  • The known side effects of Burkholderia infection are similar to the symptoms linked with other diseases of the lungs like pneumonia and cystic fibrosis. (naturalpedia.com)
  • Treatment for Burkholderia infection must be made on a case-by-case basis . (naturalpedia.com)
  • Since B. cepacia can infect the respiratory tract of patients with cystic fibrosis, eating foods rich in antioxidants, calcium, and fiber can help prevent Burkholderia infection. (naturalpedia.com)
  • Several predicted Burkholderia ATs are recognized by human humoral and cell-mediated immunity, indicating that they are expressed during infection and may be useful for diagnosis and vaccine-mediated protection. (frontiersin.org)
  • Burkholderia cepacia is an important pathogen in cystic fibrosis (CF) and an infrequent cause of nosocomial infection in non-CF patients. (umass.edu)
  • Burkholderia malleli is able to cause two forms of human infection. (oncologynurseadvisor.com)
  • We reviewed the evidence for antibiotic treatment to cure early infection with Burkholderia cepacia complex in people with cystic fibrosis and prevent it becoming permanent. (cochrane.org)
  • This review highlights an urgent need for more research into new ways of treating long-term Burkholderia cepacia infection in people with cystic fibrosis. (cochrane.org)
  • This review aims to examine the current treatment options for people with cystic fibrosis with acute infection with Burkholderia cepacia complex and to identify an evidence-based strategy that is both safe and effective. (cochrane.org)
  • To identify whether treatment of Burkholderia cepacia complex infections can achieve eradication, or if treatment can prevent or delay the onset of chronic infection. (cochrane.org)
  • Abstract Burkholderia cepacia (B. cepacia) is an opportunistic, Gram negative pathogen which causes infection mainly in immunocompromised population and associated with high rate of morbidity and mortality in cystic fibrosis patients. (slideserve.com)
  • Burkholderia pseudomallei is considered a highly pathogenic bacterium because infection is commonly fatal. (asm.org)
  • Burkholderia cepacia complex (BCC) is an emerging pathogen of nosocomial infection in chronic or critically ill patients without cystic fibrosis (CF). The objective was to evaluate the management and outcomes of BCC bacteremia in patients without CF. We conducted a retrospective study of non-CF adult patients with BCC bacteremia between January 1997 and December 2016 at 4 tertiary hospitals in South Korea. (unboundmedicine.com)
  • Burkholderia infection symptom can vary widely in people, ranging from no symptoms to serious respiratory infection. (coherentmarketinsights.com)
  • Based on recent genomic subtyping techniques, Burkholderia infection can be transmitted from person to person. (coherentmarketinsights.com)
  • Patients with lung disease such as asthma, CFTR, and COPD are at high risk of suffering from Burkholderia infection. (coherentmarketinsights.com)
  • The growing cases of COPD, asthma and other lung diseases create high risk of burkholderia infection creating an opportunity for manufacturers. (coherentmarketinsights.com)
  • Burkholderia infections also cause complications such as soft tissue infections, urinary tract infection and surgical wound infections. (coherentmarketinsights.com)
  • The increasing outbreaks of burkholderia infection has created focus towards the need for proper treatment procedure. (coherentmarketinsights.com)
  • Many organization and government policies have included burkholderia infection as one of the severe infections spread from healthcare facilities. (coherentmarketinsights.com)
  • In October, 2016, Nurse Assist Inc, recalled its normal saline flush IV syringes due to Burkholderia Cepacia bloodstream infection. (coherentmarketinsights.com)
  • In 2004, Burkholderia Cepacia was linked to nosocomial infection among Intensive Care Unit patient and was associated with exposure to sublingual probes. (coherentmarketinsights.com)
  • North America is expected to account for maximum share of the global burkholderia infections market, owing to the better diagnostic facilities, increasing awareness and government initiative for early diagnosis and treatment of burkholderia infection. (coherentmarketinsights.com)
  • Which antibiotics are best to treat worsening symptoms in people with cystic fibrosis with persistent Burkholderia cepacia complex lung infection? (cochrane.org)
  • Burkholderia arboris is a Gram-negative, aerobic, non-spore-forming bacterium of the genus Burkholderia and the family Burkholderiaceae. (wikipedia.org)
  • The phylogenetic analysis revealed, with high supporting values, distinct lineages within the genus Burkholderia . (springer.com)
  • The distinct lineages present in Burkholderia suggest that each group might represent a different genus. (springer.com)
  • This order includes the genus Burkholderia and the newly defined genera Caballeronia and Paraburkholderia . (asm.org)
  • Members of the genus Burkholderia are known to be adept at biofilm formation, which presumably assists in the survival of these organisms in the environment and the host. (ku.edu)
  • Members of the genus Burkholderia outcompete other bacteria and are preferentially selected in the mycosphere. (rug.nl)
  • Burkholderia pseudomallei is a gram-negative bacterium with dimensions 2-5μm in length and .4-.8μm in diameter in the shape of a rod. (kenyon.edu)
  • Burkholderia cepacia is a catalase-producing, non-lactose-fermenting, aerobic Gram-negative bacterium found in various aquatic environments. (thefreedictionary.com)
  • Burkholderia pseudomallei are a gram negative, bipolar, aerobic, motile rod-shaped soil dwelling bacterium. (reportbuyer.com)
  • Burkholderia pseudomallei is a gram-negative soil bacterium that is able to infect both humans and animals. (omicsonline.org)
  • Her research group focuses on understanding the host-pathogen interaction of the tropical bacterium Burkholderia pseudomallei. (omicsonline.org)
  • Sfeir MM . Burkholderia cepacia complex infections: more complex than the bacterium name suggest. (eurosurveillance.org)
  • Use sentinel laboratory protocols to Rule Out or Refer isolates for the identification of Burkholderia spp. (cdc.gov)
  • Environmental Burkholderia cepacia complex isolates in human infections. (thefreelibrary.com)
  • The overall goal of this project is to forensically characterize 100 unknown Burkholderia isolates in the US-Australia collaboration. (osti.gov)
  • We will design microarray probes to detect these SNP markers and analyze 100 Burkholderia genomic DNAs extracted from environmental, clinical and near neighbor isolates from Australian collaborators on the Burkholderia SNP microarray. (osti.gov)
  • Multilocus sequence typing of seven isolates of Burkholderia pseudomallei from India showed considerable diversity, with six different sequence types. (ajtmh.org)
  • Sixty-one Burkholderia cepacia isolates from patients with cystic fibrosis (CF) and four plant isolates were screened for production of the siderophores salicylic acid (SA), pyochelin, cepabactin, and ornibactins and fingerprinted by a PCR-based randomly amplified polymorphic DNA (RAPD) method. (asm.org)
  • B. arboris belongs to the Burkholderia cepacia complex. (wikipedia.org)
  • Burkholderia cepacia [burk-hōld-er-ee-uh si-pay-shee-uh] (also called B. cepacia) is the name for a group or "complex" of bacteria that can be found in soil and water. (cdc.gov)
  • For more information see the Notice to Readers: Manufacturer's Recall of Nasal Spray Contaminated with Burkholderia cepacia Complex . (cdc.gov)
  • The multifarious, multireplicon Burkholderia cepacia complex. (nih.gov)
  • The variable severity of Burkholderia cepacia complex infections in cystic fibrosis (CF) has recently been ascribed to differences in the virulence between genomovars. (hindawi.com)
  • Burkholderia contaminans , like other members of the Burkholderia cepacia complex, are considered to be opportunistic pathogens with generally low virulence, but a large range of virulence factors. (kenyon.edu)
  • Members of the Burkholderia cepacia complex (Bcc), found in many environments, are associated with clinical infections. (thefreelibrary.com)
  • Ball R, Brownlee KG, Duff AJ, Denton M, Conway SP, Lee TW (2010) Can Burkholderia cepacia complex be eradicated with nebulised Amiloride and TOBI? (springer.com)
  • Caraher E, Reynolds G, Murphy P, McClean S, Callaghan M (2007) Comparison of antibiotic susceptibility of Burkholderia cepacia complex organisms when grown planktonically or as biofilm in vitro. (springer.com)
  • Cardona ST, Wopperer J, Eberl L, Valvano MA (2005) Diverse pathogenicity of Burkholderia cepacia complex strains in the Caenorhabditis elegans host model. (springer.com)
  • At the beginning of this review it is essential to clarify the terminology that will be used to refer to the members of the Burkholderia cepacia complex and their relatives. (asm.org)
  • Burkholderia cepacia complex (Bcc) lung infections in cystic fibrosis (CF) patients are often associated with a steady decline in lung function and death. (asm.org)
  • Colonização por Burkholderia cepacia complex em pacientes com doença pulmonar supurativa. (usp.br)
  • INTRODUÇÃO: Em contraste aos bons resultados do transplante pulmonar no tratamento de pacientes com doença supurativa pulmonar avançada, a colonização por Burkholderia cepacia complex (BCC), sobretudo o genomovar III, vem sendo relacionada a pior prognóstico e, por conseguinte, uma contraindicação ao procedimento em alguns centros transplantadores. (usp.br)
  • INTRODUCTION: Notwithstanding the good results of lung transplantation for treatment of patients with advanced lung suppurative disease, colonization by Burkholderia cepacia complex (BCC), especially genomovar III has been related to a worse prognosis in these patients and therefore contraindication to the procedure certain centers. (usp.br)
  • Burkholderia cepacia complex (Bcc) is an opportunistic pathogen in cystic fibrosis patients which is inherently resistant to antimicrobial agents. (mdpi.com)
  • Multiple sequence alignment & phylogram with closely related sequence accessions using MEGA Software revealed this naturally occurring biocontrol bacteria belongs to Burkholderia cepacia complex genomovar I based on the Biolog identification system with 16S rDNA gene sequence analysis. (scirp.org)
  • Of onions and men: Report of cavitary community acquired pneumonia due to Burkholderia cepacia complex in an immunocompetent patient and review of the literature. (medworm.com)
  • We describe a case of an otherwise healthy, community-dwelling man who presented with subacute cavitary lung disease, the causative organism of which turned out to be Burkholderia cepacia complex. (medworm.com)
  • Without further comprehensive studies, it is difficult to draw conclusions about a safe and effective management strategy for Burkholderia cepacia complex eradication in cystic fibrosis. (cochrane.org)
  • There remain no objective guidelines for strategies to eradicate Burkholderia cepacia complex in cystic fibrosis lung disease, as these are inherently resistant to the majority of antibiotics and there has been very little research in this area. (cochrane.org)
  • Randomised or quasi-randomised studies in people with cystic fibrosis of antibiotics or alternative therapeutic agents used alone or in combination, using any method of delivery and any treatment duration, to eradicate Burkholderia cepacia complex infections compared to another antibiotic, placebo or no treatment. (cochrane.org)
  • Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. (eurosurveillance.org)
  • An outbreak of Burkholderia cepacia complex associated with intrinsically contaminated nasal spray. (eurosurveillance.org)
  • Jacobson M , Wray R , Kovach D , Henry D , Speert D , Matlow A . Sustained endemicity of Burkholderia cepacia complex in a pediatric institution, associated with contaminated ultrasound gel. (eurosurveillance.org)
  • An outbreak of Burkholderia cepacia complex infections associated with contaminated liquid docusate. (eurosurveillance.org)
  • A multistate investigation of health care-associated Burkholderia cepacia complex infections related to liquid docusate sodium contamination, January-October 2016. (eurosurveillance.org)
  • One group of bacteria that can infect the lungs of people with cystic fibrosis is called the Burkholderia cepacia complex. (cochrane.org)
  • We did not find any trials which compared groups of volunteers with exacerbations who were also infected with Burkholderia cepacia complex bacteria, who were given different treatments at random. (cochrane.org)
  • More research is needed to find out which treatments are best for improving lung function and survival and for reducing side effects and length of time spent in hospital for people infected with Burkholderia cepacia complex bacteria experiencing an exacerbation. (cochrane.org)
  • Burkholderia cepacia complex infections present a significant challenge for people with cystic fibrosis and their clinicians. (cochrane.org)
  • Multicentre randomised clinical trials are needed to assess the effectiveness of different antibiotic regimens in people with cystic fibrosis infected with organisms of the Burkholderia cepacia complex. (cochrane.org)
  • Burkholderia cepacia complex bacteria are resistant to many common antibiotics and able to acquire resistance against many more. (cochrane.org)
  • To assess the effectiveness and safety of different antibiotic regimens in people with cystic fibrosis experiencing an exacerbation and chronically infected with organisms of the Burkholderia cepacia complex. (cochrane.org)
  • Randomised and quasi-randomised controlled trials of treatments for exacerbations of pulmonary symptoms in people with cystic fibrosis chronically infected with organisms of the Burkholderia cepacia complex. (cochrane.org)
  • We will also assess the relative performance and compatibilities of existing antibodies to bind Burkholderia pathogens, in order to create optimized formulations, which will be assessed for therapeutic benefit in future challenge studies. (sbir.gov)
  • In this study, we undertook a multilocus sequence analysis of 77 type and reference strains of Burkholderia using atpD , gltB , lepA , and recA genes in combination with the 16S rRNA gene sequence and employed maximum likelihood and neighbor-joining criteria to test this further. (springer.com)
  • As a first step, we will isolate carbohydrate antigens from non-pathogenic strains of Burkholderia in forms that will generate appropriate immune responses. (sbir.gov)
  • CP000869 Burkholderia multivorans ATCC 17616 chromosome 2, complete sequence. (atcc.org)
  • Pivotal role of anthranilate dioxygenase genes in the adaptation of Burkholderia multivorans ATCC 17616 in soil. (sigmaaldrich.com)
  • In our recent screen for soil-induced genes, the expression of andA operon (andAcAdAbAa) for anthranilate catabolism in Burkholderia multivorans ATCC 17616 was found to increase dramatically in a soil sample (Nishiyama et al. (sigmaaldrich.com)
  • Other glucose nonfermenters, like Stenotrophomonas maltophilia , Alcaligenes xylosoxidans , R. pickettii , and Burkholderia gladioli , can frequently be found as well, but their role in the decline of pulmonary function is unclear ( 14 , 19 , 30 ). (asm.org)
  • In Vitro Antifungal Activity of Burkholderia gladioli pv. (mdpi.com)
  • Burkholderia gladioli pv. (mdpi.com)
  • Among these novel natural biocides are the bioactive secondary metabolites of Burkholderia gladioli pv. (mdpi.com)
  • Background and Aim Burkholderia gladioli is a rare cause of bacteraemia and sepsis in patients without predisposing factors like chronic granulomatous disease, cystic fibrosis or immunsupressive disorders. (bmj.com)
  • Burkholderia contaminans: unusual cause of biliary sepsis. (biomedsearch.com)
  • Automated bacterial identification systems identified the organism as Burkholderia cepacia, whereas DNA sequence analysis revealed that the recA gene isolate was identical to that of B. contaminans. (biomedsearch.com)
  • Comparative genome-wide analysis reveals that Burkholderia contaminans MS14 possesses multiple antimicrobial biosynthesis genes but not major genetic loci required for pathogenesis. (kegg.jp)
  • Ait-Tayeb L, Lefevre M, Passet V, Diancourt L, Brisse S, Grimont PAD (2008) Comparative phylogenies of Burkholderia , Ralstonia , Comamonas , Brevundimonas and related organism derived from rpoB , gyrB and rrs gene sequences. (springer.com)
  • Through computer simulation, 312 essential genes are identified as possible drug targets for Burkholderia pseudomallei. (kenyon.edu)
  • Hubner A, Hendrickson W. A fusion promoter created by a new insertion sequence, IS1490, aciivates transcription of 2,4,5-trichlorophenoxyacetic acid catabolic genes in Burkholderia cepacia AC1100. (atcc.org)
  • To identify host genes that are required by Burkholderia spp. (osti.gov)
  • Identificação e caracterização de genes provenientes de Burkholderia seminalis TC3.4.2R3. (usp.br)
  • AF148556 Burkholderia cepacia genomovar III 16S ribosomal RNA gene, partial sequence. (atcc.org)
  • Bernier SP, Silo-Suh L, Woods DE, Ohman DE, Sokol PA (2003) Comparative analysis of plant and animal models for characterization of Burkholderia cepacia virulence. (springer.com)
  • Liver abscess caused by Burkholderia pseudomallei in a young man: A case report and review of literature. (biomedsearch.com)
  • We report a case of isolated liver abscess caused by Burkholderia pseudomallei (B. pseudomallei) in a 29-year-old recently diagnosed diabetic, immunocompetent male. (biomedsearch.com)
  • One of these bugs, Burkholderia cepacia , causes a lot of problems for people with cystic fibrosis because it is very difficult to treat and makes their lung disease deteriorate faster than it otherwise would. (cochrane.org)
  • We looked for studies of treatments which could eliminate Burkholderia cepacia from the lungs of people with cystic fibrosis. (cochrane.org)
  • This course provides clinical laboratory scientists with information about the laboratory identification of Burkholderia spp. (cdc.gov)
  • Wright C, Leyden R, Murphy PV, Callaghan M, Velasco-Torrijos T, McClean S. Inhibition of Burkholderia multivorans Adhesion to Lung Epithelial Cells by Bivalent Lactosides. (mdpi.com)
  • Burkholderia cepacia has emerged as an important pathogen in patients with cystic fibrosis. (asm.org)
  • Burkholderia pseudomallei is thought to have biological warfare potential and its virulence is made evident by being listed as a "Category B agent" by the US centers for Disease Control. (kenyon.edu)
  • BpsIR, a LuxIR quorum-sensing homolog, is required for optimal expression of virulence and secretion of exoproducts in Burkholderia pseudomallei . (asm.org)
  • Burkholderia cepacia is a well recognised pathogen in patients with cystic fibrosis, immunocompromised patients, and those undergoing mechanical ventilation. (bmj.com)
  • The purpose of this research study was to determine if an experimental drug called Aztreonam for Inhalation Solution (AZLI) was safe and effective to treat Burkholderia lung infections in patients with cystic fibrosis (CF). (clinicaltrials.gov)
  • In the early 1980s Burkholderia cepaciabecame associated with epidemics of severe lung infections ('cepacia syndrome') traced, in many cases, to CF treatment centers and social gatherings where CF patients apparently acquired the disease from other B. cepacia-infected individuals (19). (apsnet.org)
  • Increasing prevalence of lung diseases is expected to fuel growth of the Burkholderia infections market. (coherentmarketinsights.com)
  • Misidentification of Burkholderia pseudomallei as Burkholderia cepacia by the VITEK 2 system. (thefreedictionary.com)
  • Burkholderia pseudomallei is an important cause of acute fulminant pneumonia and septicaemia in tropical regions of northern Australia and south east Asia. (bmj.com)
  • For more information see the Notice to Readers: Nosocomial Burkholderia cepacia Infections Associated with Exposure to Sublingual Probes - Texas, 2004 . (cdc.gov)
  • Outbreak of Burkholderia cepacia pseudobacteraemia caused by intrinsically contaminated commercial 0.5% chlorhexidine solution in neonatal intensive care units. (eurosurveillance.org)
  • Three-year outbreak of pseudobacteremia with Burkholderia cepacia traced to a contaminated blood gas analyzer. (eurosurveillance.org)