Bupranolol: An adrenergic-beta-2 antagonist that has been used for cardiac arrhythmia, angina pectoris, hypertension, glaucoma, and as an antithrombotic.Receptors, Adrenergic, beta-3: A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The beta-3 adrenergic receptors are the predominant beta-adrenergic receptor type expressed in white and brown ADIPOCYTES and are involved in modulating ENERGY METABOLISM and THERMOGENESIS.Adrenergic beta-3 Receptor Antagonists: Drugs that bind to and block the activation of ADRENERGIC BETA-3 RECEPTORS.Adrenergic beta-1 Receptor Antagonists: Drugs that bind to and block the activation of ADRENERGIC BETA-1 RECEPTORS.Adrenergic beta-3 Receptor Agonists: Compounds that bind to and activate ADRENERGIC BETA-3 RECEPTORS.Adrenergic beta-1 Receptor Agonists: Compounds that bind to and activate ADRENERGIC BETA-1 RECEPTORS.Adrenergic beta-Antagonists: Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.Propanolamines: AMINO ALCOHOLS containing the propanolamine (NH2CH2CHOHCH2) group and its derivatives.Butoxamine: A beta-2 selective adrenergic antagonist. It is used primarily in animal and tissue experiments to characterize BETA-2 ANDRENERGIC RECEPTORS.Receptors, Adrenergic, beta: One of two major pharmacologically defined classes of adrenergic receptors. The beta adrenergic receptors play an important role in regulating CARDIAC MUSCLE contraction, SMOOTH MUSCLE relaxation, and GLYCOGENOLYSIS.Adrenergic beta-Agonists: Drugs that selectively bind to and activate beta-adrenergic receptors.Pindolol: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)Receptors, Adrenergic, beta-1: A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-1 receptors are equally sensitive to EPINEPHRINE and NOREPINEPHRINE and bind the agonist DOBUTAMINE and the antagonist METOPROLOL with high affinity. They are found in the HEART, juxtaglomerular cells, and in the central and peripheral nervous systems.Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.Stereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Myocardial Contraction: Contractile activity of the MYOCARDIUM.Stimulation, Chemical: The increase in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.Metabolomics: The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.Canada: The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.Alberta: A province of western Canada, lying between the provinces of British Columbia and Saskatchewan. Its capital is Edmonton. It was named in honor of Princess Louise Caroline Alberta, the fourth daughter of Queen Victoria. (From Webster's New Geographical Dictionary, 1988, p26 & Room, Brewer's Dictionary of Names, 1992, p12)British Columbia: A province of Canada on the Pacific coast. Its capital is Victoria. The name given in 1858 derives from the Columbia River which was named by the American captain Robert Gray for his ship Columbia which in turn was named for Columbus. (From Webster's New Geographical Dictionary, 1988, p178 & Room, Brewer's Dictionary of Names, 1992, p81-2)Genomics: The systematic study of the complete DNA sequences (GENOME) of organisms.Health Records, Personal: Longitudinal patient-maintained records of individual health history and tools that allow individual control of access.Xylans: Polysaccharides consisting of xylose units.Cellulose: A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.Chromatography, High Pressure Liquid: Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.Phenothiazines: Compounds containing dibenzo-1,4-thiazine. Some of them are neuroactive.Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.Athletic Performance: Carrying out of specific physical routines or procedures by one who is trained or skilled in physical activity. Performance is influenced by a combination of physiological, psychological, and socio-cultural factors.Great Lakes Region: The geographic area of the Great Lakes in general and when the specific state or states are not indicated. It usually includes Illinois, Indiana, Michigan, Minnesota, New York, Ohio, Pennsylvania, and Wisconsin.Eicosapentaenoic Acid: Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.Fishes: A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.Hindlimb Suspension: Technique for limiting use, activity, or movement by immobilizing or restraining animal by suspending from hindlimbs or tails. This immobilization is used to simulate some effects of reduced gravity and study weightlessness physiology.Doping in Sports: Illegitimate use of substances for a desired effect in competitive sports. It includes humans and animals.Sports Medicine: The field of medicine concerned with physical fitness and the diagnosis and treatment of injuries sustained in exercise and sports activities.Halogens: A family of nonmetallic, generally electronegative, elements that form group 17 (formerly group VIIa) of the periodic table.Immunosuppressive Agents: Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Tacrolimus: A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.Alcohol Drinking: Behaviors associated with the ingesting of alcoholic beverages, including social drinking.Cyclosporins: A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.Graft Rejection: An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient.Sezary Syndrome: A form of cutaneous T-cell lymphoma manifested by generalized exfoliative ERYTHRODERMA; PRURITUS; peripheral lymphadenopathy, and abnormal hyperchromatic mononuclear (cerebriform) cells in the skin, LYMPH NODES, and peripheral blood (Sezary cells).Aortic Valve Prolapse: The downward displacement of the cuspal or pointed end of the trileaflet AORTIC VALVE causing misalignment of the cusps. Severe valve distortion can cause leakage and allow the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to aortic regurgitation.Athletic Injuries: Injuries incurred during participation in competitive or non-competitive sports.Racquet Sports: Games in which players use a racquet to hit a ball or similar type object.Fetal Organ Maturity: Functional competence of specific organs or body systems of the FETUS in utero.

Beta 1-, beta 2- and atypical beta-adrenoceptor-mediated relaxation in rat isolated aorta. (1/31)

beta-adrenoceptor-mediated relaxation was investigated in ring preparations of rat isolated thoracic aorta. Rings were pre-constricted with a sub-maximal concentration of noradrenaline (1 microM) and relaxant responses to cumulative concentrations of beta-adrenoceptor agonists obtained. The concentration-response curve (CRC) to isoprenaline was shifted to the right by propranolol (0.3 microM) with a steepening of the slope. Estimation of the magnitude of the shift from EC(50) values gave a pA(2) of 7.6. Selective beta(1)- and beta(2)-adrenoceptor antagonists, CGP 20712A (0.1 microM) and ICI 118551 (0.1 microM), respectively, produced 4 and 14 fold shifts of the isoprenaline CRC. Atypical beta-adrenoceptor agonists also produced concentration-dependent relaxation of aortic rings. The order of potency of the beta-adrenoceptor agonists was (-log EC(50)): isoprenaline (6. 25)>cyanopindolol (5.59)>isoprenaline+propranolol (5.11)>CGP 12177A (4.40)>ZD 2079 (4.24)>ZM 215001 (4.07)>BRL 37344 (3.89). Relaxation to CGP 12177A and ZM 215001 was unaffected by propranolol (0.3 microM). SR 59230A (+info)

The beta3-adrenoceptor-mediated relaxation induced by epinephrine in guinea pig taenia caecum. (2/31)

The mechanisms of the beta-adrenoceptor mediated relaxation induced by epinephrine in guinea pig taenia caecum were examined. The relaxant response to epinephrine was unaffected by propranolol (approximately 10(-5) M) or phentolamine (approximately 10(-5) M). The response to epinephrine was antagonized in a concentration dependent manner by bupranolol, and Schild plot of the data revealed the pA2 value of 5.87. Epinephrine significantly increased cyclic AMP level in this preparation. Bupranolol (10(-4) M) significantly decreased the cyclic AMP level that was elicited by epinephrine, whereas propranolol (10(-5) M) produced no effect. These results suggest that the relaxant response to epinephrine in the guinea pig taenai caecum is mainly mediated by beta3-adrenoceptors.  (+info)

Partial agonistic effects of carteolol on atypical beta-adrenoceptors in the guinea pig gastric fundus. (3/31)

The properties of the beta1-/beta2-adrenoceptor partial agonist carteolol were investigated in atypical beta-adrenoceptors on the guinea pig gastric fundus. Carteolol induced concentration-dependent relaxation in this tissue (pD2 = 5.55, intrinsic activity = 0.94). However, a combination of the selective beta1-adrenoceptor antagonist atenolol (100 microM) and the selective beta2-adrenoceptor antagonist butoxamine (100 microM) produced only small rightward shifts in the concentration-response curves of carteolol in the gastric fundus (pD2 = 4.91, intrinsic activity = 0.94). In the presence of both atenolol (100 microM) and butoxamine (100 microM), the non-selective beta1-, beta2- and beta3-adrenoceptor antagonist (+/-)-bupranolol (10-100 microM) caused a concentration-dependent right-ward shift of the concentration-response curves for carteolol in the guinea pig gastric fundus. Schild plot analyses of the effects of (+/-)-bupranolol against carteolol gave the pA2 value of 5.29 and the Schild slope was not significantly different from unity. Furthermore, carteolol (10 microM) weakly but significantly antagonized the relaxant responses to catecholamines ((-)-isoprenaline, (-)-noradrenaline and (-)-adrenaline), a selective beta3-adrenoceptor agonist BRL37344 ((R*,R*)-(+/-)-4-[2-[(2-(3-chlorophenyl)-2-hydroxyethyl)amino]propyl]phenoxy-acet ic acid sodium salt) and a non-conventional partial beta3-adrenoceptor agonist (+/-)-CGP12177A ([4-[3-[(1,1dimethylethyl)amino]-2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2- one] hydrochloride) in the guinea pig gastric fundus. These results suggest that the partial agonistic effects of carteolol are mediated by atypical beta-adrenoceptors in the guinea pig gastric fundus.  (+info)

(+/-)-Pindolol acts as a partial agonist at atypical beta-adrenoceptors in the guinea pig duodenum. (4/31)

The agonistic and antagonistic effects of (+/-)-pindolol (1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol) were estimated to clarify whether (+/-)-pindolol acts as a partial agonist on atypical beta-adrenoceptors in the guinea pig duodenum. (+/-)-Pindolol induced concentration-dependent relaxation with a pD2 value of 5.10 +/- 0.03 and an intrinsic activity of 0.83 +/- 0.03. However, the relaxations to (+/-)-pindolol were not antagonized by the non-selective beta1- and beta2-adrenoceptor antagonist (+/-)-propranolol (1 microM). In the presence of (+/-)-propranolol (1 microM), the non-selective beta1-, beta2- and beta3-adrenoceptor antagonist (+/-)-bupranolol (30 microM) induced a rightward shift of the concentration-response curves for (+/-)-pindolol (apparent pA2 = 5.41 +/- 0.06). In the presence of (+/-)-propranolol, (+/-)-pindolol (10 microM) weakly but significantly antagonized the relaxant effects to catecholamines ((-)-isoprenaline, (-)-noradrenaline and (-)-adrenaline), a selective beta3-adrenoceptor agonist BRL37344 ((R*,R*)-(+/-)-4-[2-[(2-(3-chlorophenyl)-2-hydroxyethyl) amino]propyl]phenoxyacetic acid sodium salt) and a non-conventional partial beta3-adrenoceptor agonist (+/-)-CGP12177A([4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1,3-dihydro-2H -benzimidazol-2-one] hydrochloride). These results demonstrate that (+/-)-pindolol possesses both agonistic and antagonistic effects on atypical beta-adrenoceptors in the guinea pig duodenum.  (+info)

Further evidence that (+/-)-carteolol-induced relaxation is mediated by beta2-adrenoceptors but not by beta3-adrenoceptors in the guinea pig taenia caecum. (5/31)

The properties of the beta1- and beta2-adrenoceptor partial agonist (+/-)-carteolol were investigated against the beta2- and beta3-adrenoceptors of the taenia caecum of the guinea pig. (--)-Isoprenaline and (+/-)-carteolol induced concentration-dependent relaxation in this tissue. The non-selective beta1- and beta2-adrenoceptor antagonist (+/-)-propranolol (10-100 nM), the selective beta2-adrenoceptor antagonist ICI 118,551 (10-100 nM) and the non-selective beta1-, beta2- and beta3-adrenoceptor antagonist (+/-)-bupranolol (10-100nM), caused a concentration-dependent rightward shift of the concentration-response curves for (--)-isoprenaline and (+/-)-carteolol. Schild regression plot analyses carried out for (+/-)-propranolol against (--)-isoprenaline and (+/-)-carteolol gave pA2 values of 8.35 and 8.24, respectively. Schild plot analyses of ICI 118,551 against (--)-isoprenaline and (+/-)-carteolol gave pA2 values of 8.47 and 8.41, respectively. Schild plot analyses of (+/-)-bupranolol against (--)-isoprenaline and (+/-)-carteolol gave pA2 values of 8.47 and 8.53, respectively. Slopes of the Schild plots were not significantly different from unity. These results suggest that the relaxant effects of (+/-)-carteolol in the guinea pig taenia caecum are mediated by beta2-adrenoceptors but not by beta3-adrenoceptors.  (+info)

Transdermal absorption of bupranolol in rabbit skin in vitro and in vivo. (6/31)

This study was designed to clarify the percutaneous penetration of bupranolol (BP), a beta-adrenoceptor antagonist, through rabbit skin and to compare the in vitro penetration with the in vivo absorption. BP penetrated across the skin slowly in the absence of enhancers in vitro. Isopropyl myristate and N-methyl-2-pyrrolidone enhanced the in vitro penetration, with a 3.6 times higher flux compared with that without enhancers. However, in the in vivo percutaneous absorption, the maximal penetration was obtained with the formulation added dlimonene, with a 3.0 times higher area under the concentration-time curve (AUC) than that for the formulation without enhancers. The plasma levels of BP determined, however, were extremely lower than the theoretical plasma steady-state concentrations predicted. The plasma levels of BP after application of these formulations were maintained in the range of 7-22 ng/ml for 30 h, of which concentrations were above the therapeutically effective concentration (1.5-4 ng/ml). Therefore, the transdermal systems will offer an efficient drug delivery system for the treatment of angina pectoris and tachycardia.  (+info)

Structure-activity relationship studies of (+/-)-terbutaline and (+/-)-fenoterol on beta3-adrenoceptors in the guinea pig gastric fundus. (7/31)

(+/-)-Terbutaline and (+/-)-fenoterol are both arylethanolamine analogs that have tertbutyl and aryliso-propyl substituents respectively at the a position on the nitrogen of the ethanolamine side chain. In the present study, we have investigated the structure-activity relationships of (+/-)-terbutaline and (+/-)-fenoterol as beta3-adrenoceptor agonists in the guinea pig gastric fundus. (+/-)-Terbutaline and (+/-)-fenoterol induced concentration-dependent relaxation of the precontracted gastric fundus with pD2 values of 4.45+/-0.10 and 5.90+/-0.09, and intrinsic activities of 1.00+/-0.03 and 0.99+/-0.01 respectively. The combination of the selective beta1-adrenoceptor antagonist (+/-)-atenolol (100 microM), and the selective beta2-adrenoceptor antagonist (+/-)-butoxamine (100 microM), produced a 2 and 6 fold rightward shift of the concentration-response curves for (+/-)-terbutaline and (+/-)-fenoterol respectively, without depressing the maximal responses. The order of potency of these agonists was (pD2 value): (+/-)-fenoterol (5.09+/-0.10) > (+/-)-terbutaline (4.13+/-0.08). In the presence of (+/-)-atenolol and (+/-)-butoxamine, however, the non-selective beta1, beta2- and beta3-adrenoceptor antagonist (+/-)-bupranolol caused a concentration-dependent rightward shift of the concentration-response curves for (+/-)-terbutaline and (+/-)-fenoterol. Schild plot analyses of the effects of (+/-)-bupranolol against these agonists gave pA2 values of 6.21+/-0.07 ((+/-)-terbutaline) and 6.37+/-0.06 ((+/-)-fenoterol) respectively, and the slopes of the Schild plot were not significantly different from unity (p>0.05). These results suggest that the relaxant responses to (+/-)-terbutaline and (+/-)-fenoterol are mainly mediated through beta3-adrenoceptors in the guinea pig gastric fundus. The beta3-adrenoceptor agonist potencies of arylethanolamine analogs depend on the size of the end of the alkylamine side chain.  (+info)

Burst-like control of lipolysis by the sympathetic nervous system in vivo. (8/31)

Rapid oscillations of visceral lipolysis have been reported. To examine the putative role of the CNS in oscillatory lipolysis, we tested the effects of beta(3)-blockade on pulsatile release of FFAs. Arterial blood samples were drawn at 1-minute intervals for 120 minutes from fasted, conscious dogs (n = 7) during the infusion of saline or bupranolol (1.5 micro g/kg/min), a high-affinity beta(3)-blocker. FFA and glycerol time series were analyzed and deconvolution analysis was applied to estimate the rate of FFA release. During saline infusion FFAs and glycerol oscillated in phase at about eight pulses/hour. Deconvolution analysis showed bursts of lipolysis (nine pulses/hour) with time-dependent variation in burst frequency. Bupranolol completely removed rapid FFA and glycerol oscillations. Despite removal of lipolytic bursts, plasma FFAs (0.31 mM) and glycerol (0.06 mM) were not totally suppressed and deconvolution analysis revealed persistent non-oscillatory lipolysis (0.064 mM/min). These results show that lipolysis in the fasting state consists of an oscillatory component, which appears to be entirely dependent upon sympathetic innervation of the adipose tissue, and a non-oscillatory, constitutive component, which persists despite beta(3)-blockade. The extinction of lipid fuel bursts by beta(3)-blockade implies a role for the CNS in the maintenance of cyclic provision of lipid fuels.  (+info)

*Bupranolol

... eye drops (0.05%-0.5%) are used against glaucoma. Bupranolol is quickly and completely absorbed from the gut. Over ... Bupranolol has a plasma half life of about two to four hours, with levels never reaching 1 µg/l in therapeutic doses. The main ... Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane ... Like other beta blockers, oral bupranolol can be used to treat hypertension and tachycardia. The initial dose is 50 mg two ...

*SR 59230A

... bupranolol, and SR 59230A, on the contraction of rat intrapulmonary artery". J. Pharmacol. Exp. Ther. 309 (1): 137-45. doi: ...

*Synephrine

... bupranolol: 0.11 μM; CGP-20,712A (β1 antagonist): 6.09 μM; ICI-118,551 (β2 antagonist): 3.58 μM; SR-5923A (β3 antagonist): 17 ...

*Cresol

Derivatives of p-cresol include: Bupranolol, a non-selective beta blocker Butylated hydroxytoluene, a common antioxidant Indo-1 ...

*List of adrenergic drugs

Bevantolol Bisoprolol Bopindolol Bornaprolol Brefonalol Bucindolol Bucumolol Bufetolol Bufuralol Bunitrolol Bunolol Bupranolol ...

*List of MeSH codes (D02)

... bupranolol MeSH D02.092.063.624.698.207 --- carteolol MeSH D02.092.063.624.698.268 --- celiprolol MeSH D02.092.063.624.698.512 ... bupranolol MeSH D02.033.100.624.210 --- carteolol MeSH D02.033.100.624.240 --- celiprolol MeSH D02.033.100.624.302 --- ... bupranolol MeSH D02.033.755.624.210 --- carteolol MeSH D02.033.755.624.240 --- celiprolol MeSH D02.033.755.624.302 --- ...

*Phenylethanolamine

This lipolysis was inhibited completely by bupranolol (considered to be a non-selective β-blocker), CGP 20712A (considered to ...

*ATC code C07

C07AA07 Sotalol C07AA12 Nadolol C07AA14 Mepindolol C07AA15 Carteolol C07AA16 Tertatolol C07AA17 Bopindolol C07AA19 Bupranolol ...

*List of drugs: Bs-Bz

... bupranolol (INN) Buprenex buprenorphine (INN) bupropion (INN) buquineran (INN) buquinolate (INN) buquiterine (INN) buramate ( ...
HPLC Application #18956: b-Blockers (Bupranolol) on Lux 5 µm Cellulose-2 by Chiral SFC. Column used: Lux® 5 µm Cellulose-2, LC Column 250 x 4.6 mm, Ea Part#: 00G-4457-E0
Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity. Its potency is similar to propranolol:http://www.drugbank.ca/drugs/DB00571.
5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylic acid - chemical information, properties, structures, articles, patents and more chemical data.
You are viewing an interactive 3D depiction of the molecule 4-{(2r)-3-[4-(diphenylmethyl)-1-piperazinyl]-2-hydroxypropoxy}-1h-indole-2-carbonitrile (C29H29N4O2) from the PQR.
Learn about Carteolol Hydrochloride (Carteolol) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications.
Tan CK., Davies M.J, McCluskey DK., Munro IR., Nweke MC., Tracey MC., Szita N., Electromagnetic stirring in a microbioreactor with non-conventional chamber morphology and implementation of multiplexed mixing, Journal of Chemical Technology and Biotechnology (2015) 1927- ...
|.. ۞ Refactoring a double negative to make it a single positive conditional if ( !item.isNotFound() )item.is found as Double-Negative Regulatory T Cells: non-conventional regulators signaling pathways influencing SLF and c-Kit-mediated survival and proliferation. The Isolation Kit is developed for the isolation of CD4-CD8-CD56-CD3+TCRα/β+ T cells from PBMCs in peripheral blood lymphocytes. To examine the…
Absynth Biologics discovers and develops vaccines and antibodies to prevent and treat bacterial infections based on proprietary, non-conventional platform for identifying novel protein antigen that harness the immune system and that use a dual-action mechanism. ...
Professional guide for Carteolol (Ophthalmic). Includes: pharmacology, pharmacokinetics, contraindications, interactions, adverse reactions and more.
3. Invest to get the best quality human resources. Finding and retaining skilled workers is a major challenge for companies operating in Africa. "Securing a supply of the best local people, recruiting in the diaspora, transferring skills from other parts of your company and working hard to retain key staff will be an essential element of success," notes E&Y.. 4. Expand from strategic economic hubs and think about non-conventional market groupings. Some African countries are much more developed than others when it comes to infrastructure, financial services and the availability of skilled labour. Investors should consider setting up their base in these countries for expansion into the rest of the continent.. "Expansion plans should also look at non-conventional regional market groupings such as urban corridors, cultural affinities and regional economic communities in order to build critical mass and drive higher returns more quickly," says the report. ...
Among five strengths of Propranolol HCl manufactured and marketed by Pliva, Inc., PLIVA 469 is found right in the middle of the row. It is 40mg (Plivas propranolol pills range from 10mg to 80mg). Pliva 469 is is a non-selective beta blocker mainly used to treat hypertension and various heart problems. Pliva makes a generic version of the medication which can otherwise be available under brand names Inderal and InnoPran XL. Pliva 469 pill is easily distinguished by its light green color ...
Among five strengths of Propranolol HCl manufactured and marketed by Pliva, Inc., PLIVA 469 is found right in the middle of the row. It is 40mg (Plivas propranolol pills range from 10mg to 80mg). Pliva 469 is is a non-selective beta blocker mainly used to treat hypertension and various heart problems. Pliva makes a generic version of the medication which can otherwise be available under brand names Inderal and InnoPran XL. Pliva 469 pill is easily distinguished by its light green color ...
Inderal La 20 MG Tablet is a popular non-selective beta blocker medicine that is used for the lowering of high blood pressure and relieving chest pain caused due to reduced blood flow to the heart. It is also used for treating complications associated with heart, blood vessels, and other organs.Know Inderal La 20 MG Tablet uses, side-effects, composition, substitutes, drug interactions, precautions, dosage, warnings only on | Practo
Its unfair that you decided to single out for a reason Edwin Casimero. He is a staunch supporter of that school of thought according to which the causes of most of the ailments that befell us are linked with the defectuous way in which most of us nourish ourselves. Hence his plea for raw, fruitarianism etc. You could not have failed to notice that he is a staunch enemy of junk food. The truth is that most what Casimero claims makes sense... True, his is an intuitionist, non-conventional approach that spits in the face of the establishment. But sooner or later, most of his daring theories prove to be right. I am not sure that cancer is a fungus (as he claims), perhaps it is up to a certain point, yet according to a recent New Scientist article, Alzheimer is a form of diabetes caused by the flawed way we feed ourselves (well, at least most of us) too much sugar and carbs, gluten and bad quality highly processed saturated oils ...
There are many alternative views on cancer treatment. This category is dedicated to non-conventional treatment of cancer and information on alternative methods of dealing with chemotherapy and radiation.
While our ability to accurately diagnose and treat allergic disease has benefited from scientific understanding of what happens during an allergic reaction, a number of tests and treatments have been promoted in the absence of any scientific rationale. Some non-conventional approaches to disease also claim that various disorders unrelated to allergy have an immune basis.…
Harnessing AWRI s yeast and bacterial research to shape next-gen Chardonnay Part 1: Wild and non-conventional yeast - Christopher Curtin, Jennifer Bellon, Eveline Bartowsky, Paul Henschke, Paul Chambers, Markus Herderich and Isak Pretorius ...
Now some of you may be here because you wanted to see me attempt to fold pie. If there is enough of a request for it, Ill see what I can do later. But...
Connexin. 43 (Cx43) is the predominant gap junction (GJ) protein in the mammalian ventricular myocardium. The precise spatial order of Cx43 GJ channels in the heart is thought vital for maintaining cardiac synchrony. Disruption or remodelng of this order is a hallmark of arrhythmic disease and has been reported in ischemic and diabetic hearts. Protein-protein interactions and modifications of the Carboxyl-terminus (CT) of CX43 are major determinants of GJ function, size, distribution and organization during normal development and disease processes. The extreme CT domain of CS43 interacts directly with the second PDZ domain of the MAGUK protein Zonula Occludens 1 (ZO-1). It has been reported that this interaction regulates phosphorylation of Cx43 and directs Cx43 GJ localization at the intercalated disk. Additionally, levels of this interaction are increased in the ischemic and dilated heart suggesting a role of Cx43 ZO-1 association in disease. Recent work from the Gourdie laboratory has ...
Non Conventional Aquatint V:. Date: May 4, 2017. Temperature: 71 F. Humidity: moderate. Researchers: Claire Crews and Sam Guerin. How does Neutralizer sprayed onto aquatinted plate effect the aquatint medium?. For this experiment we sprayed aquatint medium to cover the entire plate (sprayed for 3 minutes at a distance of 18″ with the nozzle open 2 turns), then immediately sprayed an area with neutralizer at 6″ for 3 seconds. Neutralizer caused aquatint medium to move to edges of sprayed area and drip to bottom of plate, creating some stopped out areas and some stippled areas.. Even coverage of aquatint medium on plate:. ...
Nadolol is a non-selective beta blocker used in the treatment of high blood pressure and chest pain. Additionally, it is often prescribed in the treatment of atrial fibrillation, migraine headaches, and complications of cirrhosis.
Pronethalol (Alderlin, Nethalide) was an early non-selective beta blocker clinical candidate. It was never used clinically due to carcinogenicity in mice, which was thought to result from formation of a carcinogenic naphthalene epoxide metabolite.[1] ...
Carteolol - Get up-to-date information on Carteolol side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about Carteolol
It is no secret that over the past two months, Goldman has commenced a full endorsement of Nominal GDP targetting as a method to stimulate the economy, not to mention Wall Streets bonus pool, after Ben Bernanke completely ignored Hatzius advice to reduce the Interest on Overnight Excess Reserve rate as well as subsequent pleading for a start of MBS LSAP. Mathematics once again aside, and as we demonstrated, the math works out to an non-trivial incremental $10 trillion in debt through 2016 on top of what will be issued, to catch up with the GDP growth run rate and to eliminate the excess slack in the economy, the question is whether NGDP would achieve any tangible stimulus at all, or merely reduce the Feds ever smaller arsenal of non-conventional means to boost the economy by one more approach. The attached rhetorical Q&A just released by Goldman seeks to answer that and any other left over questions one may have on NGDP as a policy measure, and further puts out the inverse strawman argument that it
Mazes are usually two-dimensional. I wanted to create a three-dimensional one," said the always non-conventional Danish architect Bjarke Ingels at the launch of his new BIG Maze at the National Building Museum (NBM) in Washington, D.C.read more. ...
The point is that the practice of medicine, whether conventional or "non-conventional" is always dependent upon the context of the culture within which it is practiced. That means that each culture has criteria upon which it decides whether something is effective or not effective. And there are no 100 per cent reliable criteria to determine whether one particular treatment will benefit each individual who undertakes it. At the moment, the litmus test for medicine in the west, is a scientific trial. However these trials are unreliable. I have friend with MS who has been presribed a cocktail of drugs, all of which are useless. When researching the efficacy of these drugs I discovered none of them had been trialed by the drug companies on unhealthy frail individuals taking many other prescription drugs, the very people they would be presribed to. Instead, drug trials are aimed first of all, at very healthy people who take no drugs at all. The target population in these situations receives a drug ...
Carteolol, one that of the oldest selective for serotonin reuptaking inhibitors, is therefore commonly been prescribed to patients with major glaucoma, open facial angle. In addition to dors and ctags investigations, members news of Congress have recently written letters to each defendant, requesting information conceming their sales slip of Carteolol a
Easy to read patient leaflet for Carteolol (Ophthalmic). Includes indications, proper use, special instructions, precautions, and possible side effects.
Debugging through IE 8, I found that if you change your path from url(/pie/ie-css3.htc); to url(../css/PIE.htc); it worked fine for me. Try that ...
In the United States, several companies are venturing into the field of algal biofuels. Algae have indisputable advantages as a biofuel feedstock. Of all the green fuel options, algae alone seem to possess the potential to provide renewable oil in quantities adequately large to substantially displace petroleum-based fuels, say experts. Large-scale production of algal biofuels is still 5-10 years away, say officials from Exxon Mobil, which is in partnership with Synthetic Genomics to produce algae-based biofuels.. Microscopic algae yield up to 100 times more oil per acre than soybeans and other common biodiesel feedstock, according to Ms. Mary Rosenthal, Executive Director of Algal Biomass Organization. Microalgae can be up to 80 per cent oil by dry weight, although that number is for wild strains that are slow growers, according to Dr. Margaret McCormick of the technology company Targeted Growth. Genetically engineered microalgae, such as those created by Targeted Growth, approach 35-45 per cent ...
GE Wind Energy, the United States, has developed a 3.6 MW offshore turbine, the largest prototype ever erected. Installed in Spain, this wind unit represents the most advanced technology yet available. Patented power electronics, variable speed rotor and specially designed offshore enhancements make this system cost-effective and highly reliable. It is easy to install and maintain in the remote, offshore environments. Based on GEs proven 1.5 MW wind turbine series, the 3.6 MW model was specifically configured for high wind speed sites. With an increased generator size, a rotor diameter of 104 m and a swept area of 8,495 m2, this version is ideal for offshore markets worldwide. It also includes GEs patented voltage control technology that facilitates grid integration by improving grid voltage stability and overall system reliability. The land-based 3.6 MW prototype has a hub height of 100 m and rated power output of 3,600 kW. The offshore variant will have a 75 m hub height since there is less ...
Non Conventional Aquatint III:. Date: May 4, 2017. Temperature: 71 F. Humidity: moderate. Researchers: Claire Crews and Sam Guerin. How does a moving stencil effect line quality and texture when sprayed with a consistent distance and aperture of spray nozzle?. In this experiment, we were interested to see the effects of moving a stencil in front of the plate while applying the spray medium in an effort to create stencil ghosts overlapping on the plate. Our stencil was made from BFK and was held 1/2″ away from plate while spraying. As I held the stencil, I gradually moved its position every 30 seconds while spraying from 12-18″ away. Spray nozzle was open 2 turns.. Spraying copper plate through stencil.. ...
An electro-active spectacle lens is disclosed. The disclosed lens includes a first lens optic. The disclosed lens also includes a first electro-active zone positioned in a cooperative relationship with the first lens optic. In certain embodiments, the electro-active lens includes a range finder positioned in a cooperative relationship with the electro-active lens.
Hong Kong (PRWEB) February 27, 2014 -- Any start-up with a business plan based on innovation, ethical trading, green technology or non-conventional business
Ajman University was founded in 1988 as a non-conventional private institution of higher education in the UAE and in the Arab world.
kick in the pie hole - MedHelps kick in the pie hole Center for Information, Symptoms, Resources, Treatments and Tools for kick in the pie hole. Find kick in the pie hole information, treatments for kick in the pie hole and kick in the pie hole symptoms.
So you know how I mentioned Jamesons and my pie fail? Well, we turned that pie frown upside-down and created an overwhelming pie success. Jameson received
Read the So I have two cans of cherry pie filling . . . discussion from the Chowhound Home Cooking, Pies food community. Join the discussion today.
Are you interested in our DIY food gift sets for pie lovers foodie? With our make-your-own homemade Scotch pie kit you need look no further.
Enzyme-catalyzed synthesis has been widely studied with lipases (EC 3.1.1.3), but feruloyl esterases (FAEs; EC 3.1.1.73) may provide advantages such as higher substrate affinity and regioselectivity in the synthesis of hydroxycinnamate saccharide esters. These compounds are interesting because of their amphiphilicity and antioxidative potential. Synthetic reactions using mono- or disaccharides as one of the substrates may moreover direct new routes for biomass upgrading in the biorefinery. The paper reviews the available data for enzymatic hydroxycinnamate saccharide ester synthesis in organic solvent systems as well as other enzymatic hydroxycinnamate acylations in ionic liquid systems. The choice of solvent system is highly decisive for enzyme stability, selectivity, and reaction yields in these synthesis reactions. To increase the understanding of the reaction environment and to facilitate solvent screening as a crucial part of the reaction design, the review explores the use of activity ...
The general objective of our lab is to understand the functions of clathrin-coated structures (CCSs) during the different steps of cancer development. CCSs recruit specific cell surface receptors and progressively shape the plasma membrane in receptor-containing vesicles that are released in the cytosol. This endocytosis machinery allows for nutrient uptake but also for the fine-tuned control of signaling pathways triggered by cell surface receptors. As a consequence, deregulation of endocytosis has been linked to many pathological situations, including cancers.. Tumor development is accompanied by dramatic changes in the mechanical characteristics of tissues. Also, when cancer cells invade the stroma to establish distant metastases, they migrate in an environment with different topological features than the tumor mass. However, it is not known how the physical parameters of the environment impact on CCSs and what are the consequences for the cell.. Our team addresses this general question by ...
The concept of programmed cell death has evolved over the years to include both apoptotic and non-apoptotic death mechanisms. This study describes a novel form of non-apoptotic cell death induced as a result of dysregulated macropinocytosis. We have named this cell death "methuosis". Methuosis is observed when the activated form of Ras GTPase is over-expressed in glioblastoma cells. It is accompanied by the accumulation of large phase-lucent cytoplasmic vacuoles, followed by rounding up, detachment, and disintegration of the cells. The vacuoles quickly take up extracellular fluid-phase tracers, a hallmark of macropinosomes. Our studies also show that the Ras-induced vacuoles are not acidic and are negative for LC3-II (a marker for autophagosomes), transferrin and EEA1 (endosomal markers). These observations rule out the vacuoles originating from autophagosomal, endosomal or lysosomal compartments. Even though caspase activation is observed in dying cells, death is not prevented by zVAD-fmk, a ...
The power of full engagement is necessary when wanting to make huge changes in the market. Stay on top of your health and continue to experience tremendous energy with Dan Carlin and his telemedical clinic.. Dan Carlin is a Physician and founder of WorldClinic, a concierge telemedicine company providing 24/7 healthcare. This innovative online service is on the cutting edge of how the medical industry will change in the future.. As a proactive, non-conventional, health physician, Dan is for the proliferation in the new age of individuals and their families. With World Clinic, you get medical care when and where you need it.. ...
Infrared light activation as a non-conventional energy source has become an important method that can be used to carry out a wide range of reactions with short reaction times and high yields.
Incorporating performance ingredients in a formula does not guarantee they will penetrate the skin and deliver the claimed benefits. This review presents topical delivery approaches introduced in the past five years to improve the efficacy of benefit ingredients for skin care. Examples include molecular, carrier and Trojan horse delivery. Non-conventional delivery systems also are described.
When it comes to pie, my mantra is I must increase my crust. But even carbohydrate addicts find themselves with extra scraps of pie dough from time to time. And I now have the best solution for making use of them: Pie Fries.
Coincidentally, I really love lemon meringue pie. Ive never tried to make one, as one of my youth in Atlanta made (probably makes) the best ever lemon meringue. I have been known to invite myself over to her house for pie. Im sad to live so far away now ...
The Law N° 20,257 better known as Non-Conventional Renewable Energy Law (NCRE Law), enacted on 1 April 2008, aims to fulfill future energy requirements by developing non-conventional renewable energy sources, such as geothermal, wind, solar, tidal, biomass and small hydroelectric plants.. The law requires electricity providing companies, withdrawing electricity to supply their contract commitments, to demonstrate that a certain percentage of their total energy committed was injected in the system by non-conventional energy sources. The energy can be produced by their own plants, or by contracting from third-parties.. This quota came into force at the start of 2010, and until 2014 will require 5% of electricity to come from non-conventional renewable energy sources. Starting from 2015, the obligation will be increased by 0.5% annually, reaching 10% in 2024.. The law will apply to all agreements executed as of 31 May 2007 (new agreements, renewals, extensions, or similar arrangements). ...
The Law N° 20,257 better known as Non-Conventional Renewable Energy Law (NCRE Law), enacted on 1 April 2008, aims to fulfill future energy requirements by developing non-conventional renewable energy sources, such as geothermal, wind, solar, tidal, biomass and small hydroelectric plants.. The law requires electricity providing companies, withdrawing electricity to supply their contract commitments, to demonstrate that a certain percentage of their total energy committed was injected in the system by non-conventional energy sources. The energy can be produced by their own plants, or by contracting from third-parties.. This quota came into force at the start of 2010, and until 2014 will require 5% of electricity to come from non-conventional renewable energy sources. Starting from 2015, the obligation will be increased by 0.5% annually, reaching 10% in 2024.. The law will apply to all agreements executed as of 31 May 2007 (new agreements, renewals, extensions, or similar arrangements). ...
FEEDING careplan on knowledge deficit on wound care TUBE (G-TUBE) CONTINUOUS FEEDING Patient has a gastrostomy tube with continuous feedings. Is at risk for.Propranolol versus control: Aronow, 1997: Propranolol 30 mg 3 times daily versus no propranolol: patients ,=62 years of age with New York Heart Association.Nutrition & Santé finds a unique balance between nutrition and pleasure, research and naturalness.Propranolol is a sympatholytic non-selective beta blocker. Sympatholytics are used to treat hypertension, anxiety and panic. It was the first successful beta blocker.. session 2: diabetes education today in migrating populations session 3:. replay the desg sympo 2015. the patient education journey, past, present, future ...
Explores relationships between spectroscopic findings and physical properties of polymers. Thirty-five chapters are divided into six sections covering fundamental concepts in FT-IR, FT-Raman, fluorescence spectroscopy and FT-Mass Spectrometry of polymers; crystalline polymers and copolymers; surfaces and interfaces of polymers; spectroscopic approaches to polymers in solutions and polymer networks; spectroscopy combined with thermally induced processes in polymers; and polymer analysis and surface modifications using non-conventional energy sources. Includes tutorial chapters designed to assist newcomers to the field.Urban, Marek W. is the author of Structure-Property Relations in Polymers: Spectroscopy and Performance, Vol. 23 with ISBN 9780841225251 and ISBN 0841225257. [read more] ...
Any type of non-conventional mesothelioma treatment, which includes chemotherapy, radiation, and tumor-removing surgery, is commonly considered alternative.
Typically, alternative medicine differs from traditional medicine in that alternative medicine is older and what we might call non-conventional medicine or
MK Yuval Steinitz (Likud), chairman of the Knesset Foreign Affairs and Defense Committee, announced on Tuesday that the committee had approved a law proposed by the IDF in which it would collect, refurbish and redistribute gas masks to the population. The decision came in order to bring the masks up to par with new technological standards. Similar bills had come before the committee three times in the past, but the MKs had declined to pass it on because the procedure proposed in the bills would leave too much time between collection and redistribution leaving the population exposed to a potential non-conventional strike. According to the new bill, however, the IDF would stock up on new masks before beginning the collection process, thus significantly cu tting the time during which citizens would be without their masks. The IDF estimated that the actual collection and redistribution would take between 4 to 6 days. The army has promised to initiate the program within two years. ...
Rasd1 is becoming somewhat of avant-garde member of the Ras family of GTPases by performing many non-conventional signaling functions. Our identification of Rasd1 in Avp neurons starts a new chapter for this small GTPase. Here we show that Rasd1 is rapidly induced by stress in the PVN, and by elevated plasma osmolality in the PVN and SON of the hypothalamus. We propose that the abundance of RASD1 in MCN and PCNs, based on its inhibitory actions on CREB phosphorylation, is an important mechanism for controlling the transcriptional responses to stressors in both the PVN and SON. In MCN we show, by virally mediated overexpression of Rasd1, that Rasd1 inhibits HS induced stimulation of cAMP inducible genes. When a CAAX box deficient mutant form of Rasd1 is expressed in the SON cAMP inducible genes were further increased by SL. These effects likely occur through modulation of cAMP-PKA-CREB signaling pathway.. Our interest in Rasd1 began following identification increased expression of this gene in ...
How Digoxin (lanoxin) works: INCREASES CONTRACTILITY OF THE HEART: TECH Term, it creates a POSITIVE INOTROPIC EFFECT. The Positive INOTROPIC Effect occur
I like a good mincemeat pie, but not many people do, says Eleanor Froelich of Rochester, MI, so I cut the flavor of the mincemeat by adding apples and other fruits. Now, everyone loves her pie -- including us!
27 minutes - Compare public transit, taxi, biking, walking, driving, and ridesharing. Find the cheapest and quickest ways to get from The Halal Guys to Pies n Thighs.
A facile synthesis of some 4-hydroxychalcones (3a-3j) by the condensation of various substituted benzaldehydes and 4-hydroxyacetophenone has been described. It is prepared by Claisen-Schmidt condensation. This is a comparative study of synthesizing compounds by conventional as well as non-conventional microwave irradiation in a commercially modified microwave oven and thus confirms the possible intervention of specific (non-thermal) microwave effect. The research is focused on the remarkable reaction rate enhancement by the use of various non-conventional microwave irradiations which minimizes the time and solvents in reactions. The microwave method offers several advantages like simple procedure, fast reaction rate, mild reaction condition and improved yields as compared to conventional methods. Variety of functional groups such as nitro, chloro, dimethylamino, methoxy, methyl and hydroxy survived under the reaction conditions. The structures of newly synthesized compounds have been established ...
Background Portugal has a strong tradition of conventional western healthcare. So it provides a natural case study for the relationship between Complementary/Alternative Medicine (CAM) and Western Medicine (WM). This work aims to test the relationship between CAM and WM users in the diagnosis and treatment stages and to estimate the determinants of CAM choice. Methods The forth Portuguese National Health Survey is employed to estimate two single probit models and obtain the correlation between the consumption of CAM and WM medicines in the diagnosis and treatment stages. Results Firstly, both in the diagnosis and the treatment stage, CAM and WM are seen to be complementary choices for individuals. Secondly, self-medication also shows complementarity with the choice of CAM treatment. Thirdly, education has a non-linear relationship with the choice of CAM. Finally, working status, age, smoking and chronic disease are determinant factors in the decision to use CAM. Conclusion The results of this work
Mitchel Goldman M.D. is double-board certified dermatologist and cosmetic surgeon, recognized by the American Board of Dermatology and the American Board of Cosmetic Surgery.. He is a volunteer Clinical Professor in Medicine/Dermatology at the University of California, San Diego and the founder and Medical Director of Cosmetic Laser Dermatology in San Diego. His many areas of cosmetic surgical expertise include:. ...
Anticipatively some inputs in previous discussion threads addressed most of this financing aspect of the equation ahead… As most cant help pointing out the issue without proposing alternatives, solutions to the road forward; having this financing topic by itself will surely help in devising specific action items worth considering by the Bank. As central it is that it can be noticed, at the end of the day, despite all the potential here and there, bringing forth a Gender in the Transformation of Africas Agriculture work requires non-conventional financing, at least in the underwriting process. Specific to the areas covered herein, to my opinion, for substantial answers to the questions below, as outlined, and in a telegraphic sort of response:. Question: What are the main challenges to gender equality in agriculture finance?. Response: Among other structural and systemic disconnects, inadequate accounting systems, in sync with conventional solvency models to commercial financing, mostly ...
This paper presents a novel rotation estimation approach based on 3D mesh representation of spherical images. Indeed, unit sphere is becoming a natural space for projecting images captured from the central cameras (conventional and non-conventional cameras, as omnidirectional camera) and obtaining the spherical images. The proposed method relies on representing the spherical images into a 3D space based on image intensities. Spherical harmonic coefficients are then calculated for the 3D mesh surfaces and used to estimate an initial rotation between the underlying spherical images in spectral domain. The optimal rotation is then refined through the ICP algorithm. Experimental results, using synthetic and real image dataset, demonstrate the effectiveness of the proposed approach for rotation estimation, as well as its robustness against real conditions and images occlusion. A comparison between the proposed method and competitive ones, is performed.
Apple Pie Apple Pie Apple Pie Apple Pie Apple Pie Apple Pie Apple Pie Apple Pie Apple Pie Apple Pie Apple Pie Apple Pie Apple Pie Apple Pie ...
L zn Pie any Spa Hotel Grand Splendid. Pie any l zn Spa Hotel Grand Splendid. Spa Hotel Grand Splendid Winterova 29 ubytov n a l ze sk slu by L zn Pie any. L zn Pie any l ze sk a wellness pobyty.
Grasshopper pie is a type of chiffon pie with a cookie crust. Most grasshopper pies are dyed green, and are typically flavored...
and then I saw... the pies! 5 kinds, two apple, pecan pie, pumpkin pie and the best ever Banana Pudding Pie... it was exactly like banana pudding in the form of a pie- with a nilla wafer crust... I had a small slice of all except pumpkin. ...
At 1gram of fat per bar, these are the lowest fat and highest performing mince pies money can buy! As with last year, the TORQ Elves have committed to only one production run for 2018 and they are in stock now. We have had so many requests to keep this flavour rolling all year round, but its not going to happen - its a special bar for a special time of year. Thats not to say that it would be wrong for you to stock up with enough mince pie bars to keep you fuelled for the next 12 months if thats what you want to do - we know many of you will, because they have a 12-month best before date. Just make sure you do it soon, because when theyre gone, theyre gone!. Available at all good cycling, running and outdoor stores nationwide, or click HERE to purchase online. You can also build your own mixed flavour box if you want to combine our Mince Pie bars with some of our other fantastic flavours.. ...
Enjoy these chocolaty pies made using Pillsbury® cookies and pie crusts - a wonderful stuffed dessert thats ready in 25 minutes.
Lucky Leaf No Sugar Added Pie Filling is sweetened with Splenda no calorie sweetener, and has up to 65% fewer calories than regular pie filling.
Heres an apple pie that Liz and I made together. Shes quite the excellent helper. Oddly enough, she didnt really like it that much, but Brian thought it was one of the best pies hes eaten. Im not just saying that either. I only make 1 or 2 pies a year (if that) so I guess its possible that you can get lucky and make an excellent pie once in awhile. I told him if I made another one tomorrow, itd probably taste totally different ...

Bupranolol - WikipediaBupranolol - Wikipedia

Bupranolol eye drops (0.05%-0.5%) are used against glaucoma. Bupranolol is quickly and completely absorbed from the gut. Over ... Bupranolol has a plasma half life of about two to four hours, with levels never reaching 1 µg/l in therapeutic doses. The main ... Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane ... Like other beta blockers, oral bupranolol can be used to treat hypertension and tachycardia. The initial dose is 50 mg two ...
more infohttps://en.wikipedia.org/wiki/Bupranolol

Bupranolol - DrugBankBupranolol - DrugBank

Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane ... Bupranolol. Accession Number. DB08808. Type. Small Molecule. Groups. Experimental. Description. Bupranolol is a non-selective ... Bupranolol hydrochloride. DTC2G3GDPL. 15148-80-8. WJUUZHQWGKSLIJ-UHFFFAOYSA-N. International/Other Brands. Betadrenol (Desma) ... 1,10-Phenanthroline may increase the bradycardic activities of Bupranolol.. 3-isobutyl-1-methyl-7H-xanthine. The risk or ...
more infohttps://www.drugbank.ca/drugs/DB08808

Phenomenex HPLC Application #21072: Bupranolol on Lux 5µm Cellulose-1 by SFCPhenomenex HPLC Application #21072: Bupranolol on Lux 5µm Cellulose-1 by SFC

Bupranolol on Lux 5µm Cellulose-1 by SFC. Column used: Lux® 5 µm Cellulose-1, LC Column 250 x 4.6 mm, Ea Part#: 00G-4459-E0 ...
more infohttp://www.phenomenex.com/Application/Detail/21072

Phenomenex HPLC Application #18956: b-Blockers (Bupranolol) on Lux 5 µm Cellulose-2 by Chiral SFCPhenomenex HPLC Application #18956: b-Blockers (Bupranolol) on Lux 5 µm Cellulose-2 by Chiral SFC

Bupranolol) on Lux 5 µm Cellulose-2 by Chiral SFC. Column used: Lux® 5 µm Cellulose-2, LC Column 250 x 4.6 mm, Ea Part#: 00G- ... b-Blockers (Bupranolol) on Lux 5 µm Cellulose-2 by Chiral SFC. ...
more infohttp://www.phenomenex.com/Application/Detail/18956

Bupranolol | CTDBupranolol | CTD

Bupranolol 2-. ((1-. (2-. chloro-. 5-. methylphenoxy)-. 3-. tert-. butylamino-. 2-. propoxy)succinyl)-. 1,3- ... Bupranolol 2.. Chemicals ← Organic Chemicals ← Alcohols ← Propanols ← Propanolamines ← Phenoxypropanolamines ← Bupranolol 3.. ...
more infohttp://ctdbase.org/detail.go?type=chem&acc=D002046

Bupranolol IC50 | healthweblognews.infoBupranolol IC50 | healthweblognews.info

Posted in: Acyl-CoA cholesterol acyltransferase ⋅ Tagged: Bupranolol IC50, Rabbit Polyclonal to CARD11 ... Nevertheless, all current BCL-2 family members Bupranolol IC50 inhibitors cannot employ the greater divergent MCL1 molecule, ... Bupranolol IC50 and theme getting together with Ub-containing book DUB family members (MINDY). Lately, various key protein ... have already been revealed to end up being exquisitely governed by a number Bupranolol IC50 of deubiquitinating enzymes11C19. ...
more infohttp://healthweblognews.info/tag/bupranolol-ic50/

Phenomenex HPLC Application #18956: b-Blockers (Bupranolol) on Lux 5 µm Cellulose-2 by Chiral SFCPhenomenex HPLC Application #18956: b-Blockers (Bupranolol) on Lux 5 µm Cellulose-2 by Chiral SFC

Bupranolol) on Lux 5 µm Cellulose-2 by Chiral SFC. Column used: Lux® 5 µm Cellulose-2, LC Column 250 x 4.6 mm, Ea Part#: 00G- ... b-Blockers (Bupranolol) on Lux 5 µm Cellulose-2 by Chiral SFC. ...
more infohttps://www.phenpreview.com/Application/Detail/18956

Dronedarone (Oral Route) Description and Brand Names - Mayo ClinicDronedarone (Oral Route) Description and Brand Names - Mayo Clinic

Do not use this medicine if you are also using cyclosporine (Gengraf®, Neoral®, Sandimmune®), ritonavir (Norvir®), medicine for depression (such as amitriptyline, nefazodone, nortriptyline, Elavil®, Serzone®), medicine for heart rhythm problems (such as amiodarone, disopyramide, dofetilide, flecainide, propafenone, quinidine, sotalol, Cardioquin®, Cordarone®, Norpace®, Tikosyn®), medicine for infections (such as clarithromycin, erythromycin, itraconazole, ketoconazole, telithromycin, voriconazole, Ery-tab®, Nizoral®, Vfend®), or a phenothiazine medicine (such as chlorpromazine, prochlorperazine, promethazine, thioridazine, Compazine®, Mellaril®, Phenergan®, Thorazine®, Trilafon®). Using these medicines together may cause serious side effects. Check with your doctor right away if you develop any of the following: chest pain, shortness of breath, swelling of your hands, ankles, or feet, or weight gain. These may be symptoms of heart failure. This medicine can cause changes in ...
more infohttps://www.mayoclinic.org/drugs-supplements/dronedarone-oral-route/description/drg-20073151?p=1

Dronedarone (Oral Route) Side Effects - Mayo ClinicDronedarone (Oral Route) Side Effects - Mayo Clinic

Do not use this medicine if you are also using cyclosporine (Gengraf®, Neoral®, Sandimmune®), ritonavir (Norvir®), medicine for depression (such as amitriptyline, nefazodone, nortriptyline, Elavil®, Serzone®), medicine for heart rhythm problems (such as amiodarone, disopyramide, dofetilide, flecainide, propafenone, quinidine, sotalol, Cardioquin®, Cordarone®, Norpace®, Tikosyn®), medicine for infections (such as clarithromycin, erythromycin, itraconazole, ketoconazole, telithromycin, voriconazole, Ery-tab®, Nizoral®, Vfend®), or a phenothiazine medicine (such as chlorpromazine, prochlorperazine, promethazine, thioridazine, Compazine®, Mellaril®, Phenergan®, Thorazine®, Trilafon®). Using these medicines together may cause serious side effects. Check with your doctor right away if you develop any of the following: chest pain, shortness of breath, swelling of your hands, ankles, or feet, or weight gain. These may be symptoms of heart failure. This medicine can cause changes in ...
more infohttps://www.mayoclinic.org/drugs-supplements/dronedarone-oral-route/side-effects/DRG-20073151?p=1

Category:Beta blockers - Wikimedia CommonsCategory:Beta blockers - Wikimedia Commons

beta bloqueador (es); Béta receptor blokkolók (hu); betablokeatzaile (eu); Beta blocker (ms); Betablocker (de); Beta blocker (pam); بلوک کننده بتا (fa); Β受体阻断药 (zh); Dagirên bêta-wergirên adrênalînê (ku); Beta-blocant (ro); 交感神経β受容体遮断薬 (ja); betablockerare (sv); Бета-блокатор (uk); Dagirên bêta-wergirên adrênalînê (ku-latn); Beetasalpaaja (fi); Beta-blokátor (cs); Beta blokator (bs); Betabloccanti (it); বিটা ব্লকার (bn); bêta-bloquant (fr); Beetablokaatorid (et); 베타 차단제 (ko); חוסמי בטא (he); blocador dadrenoreceptors beta (ca); Бета блокатор (mk); Beta blokator (sr-el); Бета блокатор (sr-ec); Bēta adrenoblokatori (lv); bloqueador beta-adrenérgico (pt); бета блокатор (sr); Бета-адреноблокаторы (ru); Beta-blokker (da); Bètablokker (nl); Leki beta-adrenolityczne (pl); Beta blocker (id); betablokkar (nn); betablokker (nb); Beta ...
more infohttps://commons.wikimedia.org/wiki/Category:Beta_blockers

Fingolimod HydrochlorideFingolimod Hydrochloride

Bupranolol (major, theoretical). *. C*Carteolol (major, theoretical). *Carvedilol (major, theoretical). *Celiprolol (major, ...
more infohttps://www.medpagetoday.com/drugs/Fingolimod-Hydrochloride/929699

Dr. Sears Zone OmegaRx 2 Sport Fish Oil | High PurityDr. Sears' Zone OmegaRx 2 Sport Fish Oil | High Purity

Zone OmegaRx 2 Sport omega-3s have 25% more DHA potency than before, higher EPA content to boost athletic performance, and GLA to enhance muscle recovery.
more infohttps://www.zonediet.com/product/omega-3-fish-oil/dr-sears-omegarx2-sport-fish-oil-120-capsules/

Dr. Sears Zone OmegaRx 2 Liquid Fish Oil | High PurityDr. Sears' Zone OmegaRx 2 Liquid Fish Oil | High Purity

Zone OmegaRx 2 liquid fish oil are high purity omega-3s that help reduce cellular inflammation, improve heart health, brain function, & long-term wellness.
more infohttps://www.zonediet.com/product/omega-3-fish-oil/dr-sears-omegarx-2-fish-oil-10oz-liquid/

Synephrine - WikipediaSynephrine - Wikipedia

... bupranolol:[p] 0.11 μM; CGP-20,712A (β1 antagonist): 6.09 μM; ICI-118,551 (β2 antagonist): 3.58 μM; SR-5923A (β3 antagonist): ...
more infohttps://en.m.wikipedia.org/wiki/Synephrine

Beta-1 adrenergic receptor - DrugBankBeta-1 adrenergic receptor - DrugBank

Bupranolol. approved. yes. antagonist. Details. DB00852. Pseudoephedrine. approved. unknown. agonistpartial agonist. Details. ...
more infohttps://www.drugbank.ca/biodb/bio_entities/BE0000172

Nefazodone : Wikis (The Full Wiki)Nefazodone : Wikis (The Full Wiki)

Bupranolol • Burocrolol • Butaxamine • Butidrine • Butofilolol • Capsinolol • Carazolol • Carpindolol • Carteolol • Carvedilol ...
more infohttp://www.thefullwiki.org/Nefazodone

Amphetamine : Wikis (The Full Wiki)Amphetamine : Wikis (The Full Wiki)

Bupranolol • Burocrolol • Butaxamine • Butidrine • Butofilolol • Capsinolol • Carazolol • Carpindolol • Carteolol • Carvedilol ...
more infohttp://www.thefullwiki.org/Amphetamine

Lipid alcohols as new immunosuppressive and antiviral drugs - Patent # 6177469 - PatentGeniusLipid alcohols as new immunosuppressive and antiviral drugs - Patent # 6177469 - PatentGenius

... bupranolol; oxyphenbutazone; oestrogen; salicylic acid; propanolol; ascorbic acid; spongiadiol; Diclofenac, isospongiadiol; ... bupranolol; oxyphenbutazone; oestrogen; salicylic acid; propanolol; ascorbic acid: spongiadiol; Diclofenac, isospongiadiol; ...
more infohttp://www.patentgenius.com/patent/6177469.html

Controversial Ingredients - Reviews.comControversial Ingredients - Reviews.com

Advertisement Disclosure Reviews.com has an advertising relationship with some of the offers included on this page. However, the rankings and listings of our reviews, tools and all other content are based on objective analysis. For more information, please check out our full Advertiser Disclosure. Reviews.com strives to keep its information accurate and up to date. The information in our reviews could be different from what you find when visiting a financial institution, service provider or a specific products website. All products are presented without warranty.. ...
more infohttps://www.reviews.com/research/protein-powder-controversial-ingredients/

JCI -
Volume 111, Issue 2JCI - Volume 111, Issue 2

Bupranolol completely removed rapid FFA and glycerol oscillations. Despite removal of lipolytic bursts, plasma FFAs (0.31 mM) ... during the infusion of saline or bupranolol (1.5 μg/kg/min), a high-affinity β3-blocker. FFA and glycerol time series were ...
more infohttps://www.jci.org/111/2

Noradrenergic and specific serotonergic antidepressantNoradrenergic and specific serotonergic antidepressant

Bupranolol • Burocrolol • Butaxamine • Butidrine • Butofilolol • Capsinolol • Carazolol • Carpindolol • Carteolol • Carvedilol ...
more infohttps://en.academic.ru/dic.nsf/enwiki/649731

Dopping tiltólista - 2013 - Hatóanyag szerinti teljes listaDopping tiltólista - 2013 - Hatóanyag szerinti teljes lista

bupranolol) / (P.2) / (). *buprenorphine) / (S7) / (Bupren tbl.). *buprenorphine) / (S7) / (Buprenorphine Alkaloid nyelvalatti ...
more infohttp://sportorvos.hu/sportorvos/20130930/dopping_tiltolista__2013__hatoanyag_szerinti_teljes_lista/

Vaithiyalingam S[au] - PubMed - NCBIVaithiyalingam S[au] - PubMed - NCBI

Cardiovascular effects of transdermally delivered bupranolol in rabbits: effect of chemical penetration enhancers. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Vaithiyalingam+S%5Bau%5D&dispmax=50
  • A percutaneous method of correcting extensive metabolism of bupivacaine, comprising administering bupranolol to a human being cheapened in need thereof. (gonzoz.com)
  • Bupranolol has a plasma half life of about two to four hours, with levels never reaching 1 µg/l in therapeutic doses. (wikipedia.org)
  • The impact of salbutamol was neutralized by all administered antagonists, while a relaxing effect of BRL 37344 was completely inhibited by bupranolol and partially by propranolol. (animalsciencepublications.org)