Bunyamwera virus
Bunyaviridae
Orthobunyavirus
A genus of the family BUNYAVIRIDAE containing over 150 viruses, most of which are transmitted by mosquitoes or flies. They are arranged in groups defined by serological criteria, each now named for the original reference species (previously called serogroups). Many species have multiple serotypes or strains.
Nucleocapsid Proteins
Hemorrhagic Fevers, Viral
A group of viral diseases of diverse etiology but having many similar clinical characteristics; increased capillary permeability, leukopenia, and thrombocytopenia are common to all. Hemorrhagic fevers are characterized by sudden onset, fever, headache, generalized myalgia, backache, conjunctivitis, and severe prostration, followed by various hemorrhagic symptoms. Hemorrhagic fever with kidney involvement is HEMORRHAGIC FEVER WITH RENAL SYNDROME.
Virus Replication
Cercopithecus aethiops
Arboviruses
Arthropod-borne viruses. A non-taxonomic designation for viruses that can replicate in both vertebrate hosts and arthropod vectors. Included are some members of the following families: ARENAVIRIDAE; BUNYAVIRIDAE; REOVIRIDAE; TOGAVIRIDAE; and FLAVIVIRIDAE. (From Dictionary of Microbiology and Molecular Biology, 2nd ed)
Viral Nonstructural Proteins
Cricetinae
Seroepidemiology of California and Bunyamwera serogroup (Bunyaviridae) virus infections in native populations of Alaska. (1/101)
This study investigated the geographic distribution and prevalence of antibodies to California and Bunyamwera serogroup viruses in Native populations of Alaska, and demographic and ecologic risk factors associated with exposure. Sera (n = 1,635) from 18 communities were screened using an ELISA. All age groups were tested for antibodies to Jamestown Canyon (JC), Inkoo (INK), snowshoe hare (SSH), and Northway (NOR) viruses; persons > or = 45 years old (n = 90) from six communities were additionally tested for antibodies to Tahyna (TAH), Batai (BAT), Cache Valley (CV), and Sindbis (SIN) viruses. Thirty free-ranging mammals were tested by a plaque reduction neutralization test (PRNT) for antibodies to all eight viruses and to Getah (GET) virus. In Natives, overall antibody prevalence was 24.9% (JC = 17.6%, monotypic JC = 6.5%, INK = 11.1%, monotypic INK = 0.6%, SSH = 6.8%, monotypic SSH = 3.5%, and NOR = 6.2%). Five TAH, CV, and BAT virus exposures may be serologic cross-reactions, and no SIN virus antibodies were detected. Sindbis-like virus antibodies were found in 30% of the mammals. Most mammals had antibodies to NOR (83.3%) and California serogroup (70.0%) viruses; no GET virus exposures were found. Significant risk factors for human bunyavirus exposures were age group, ethnic-linguistic group, biotic province, climate zone, terrestrial vegetation, and presence of some ungulates and small mammals in communities. Sex was not a significant risk factor. (+info)RNA binding properties of bunyamwera virus nucleocapsid protein and selective binding to an element in the 5' terminus of the negative-sense S segment. (2/101)
The genome of Bunyamwera virus (BUN) (family Bunyaviridae, genus Bunyavirus) comprises three negative-sense RNA segments which act as transcriptional templates for the viral polymerase only when encapsidated by the nucleocapsid protein (N). Previous studies have suggested that the encapsidation signal may reside within the 5' terminus of each segment. The BUN N protein was expressed as a 6-histidine-tagged fusion protein in Escherichia coli and purified by metal chelate chromatography. An RNA probe containing the 5'-terminal 32 and 3'-terminal 33 bases of the BUN S (small) genome segment was used to investigate binding by the N protein in vitro using gel mobility shift and filter binding assays. On acrylamide gels a number of discrete RNA-N complexes were resolved, and analysis of filter binding data indicated a degree of cooperativity in N protein binding. RNA-N complexes were resistant to digestion with up to 1 microg of RNase A per ml. Competition assays with a variety of viral and nonviral RNAs identified a region within the 5' terminus of the BUN S segment for which N had a high preference for binding. This site may constitute the signal for initiation of encapsidation by N. (+info)Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis. (3/101)
Bunyamwera virus (family Bunyaviridae, genus Bunyavirus) contains a tripartite negative-sense RNA genome. The smallest RNA segment, S, encodes the nucleocapsid protein N and a nonstructural protein, NSs, in overlapping reading frames. We have generated a mutant virus lacking NSs, called BUNdelNSs, by reverse genetics. Compared with the wild-type (wt) virus, BUNdelNSs exhibited a smaller plaque size and generated titers of virus approximately 1 log lower. In mammalian cells, the mutant expressed greatly increased levels of N protein; significantly, the marked inhibition of host cell protein synthesis shown by wt virus was considerably impaired by BUNdelNSs. When inoculated by the intracerebral route BUNdelNSs killed BALB/c mice with a slower time course than wt and exhibited a reduced cell-to-cell spread, and titers of virus in the brain were lower. In addition, the abrogation of NSs expression changed Bunyamwera virus from a noninducer to an inducer of an interferon-beta promoter. These results suggest that, although not essential for growth in tissue culture or in mice, the bunyavirus NSs protein has several functions in the virus life cycle and contributes to viral pathogenesis. (+info)The Bunyamwera virus nonstructural protein NSs inhibits viral RNA synthesis in a minireplicon system. (4/101)
The small (S) genomic segment of Bunyamwera virus (family Bunyaviridae, genus Bunyavirus) encodes the nucleocapsid protein, N, and a nonstructural protein, NSs, in overlapping reading frames. In order to elucidate the function of NSs, we established a plasmid-based minireplicon system using mammalian cells that express large amounts of T7 RNA polymerase. Expression of N, the viral polymerase protein (L), and a minireplicon containing a reporter gene was sufficient to reconstitute functional virus nucleocapsids. Coexpression of NSs, however, led to a dose-dependent decrease in reporter activity without affecting expression of controls. The inhibition could not be reversed by overexpression of N, L or the minireplicon, indicating that the NSs effect was not caused by a reduction in virus gene expression. The NSs proteins of two other members of the Bunyavirus genus, Guaroa virus and Lumbo virus, were also inhibitory in our system. The intracellular localisation of Bunyamwera virus NSs was investigated and found to be predominantly cytoplasmic, but intranuclear inclusion was also detected. Taken together, these data suggest that, in mammalian cells, the bunyavirus NSs protein controls the activity of the viral polymerase by a highly conserved mechanism. (+info)Protein synthesis in Bunyamwera virus-infected cells. (5/101)
In Vero cells infected with Bunyamwera virus there is a rapid inhibition of cell RNA and protein synthesis to levels of 30 and 3% respectively of the control rate, both the rate of inhibition and the time lag before its initiation being multiplicity dependent. Using u.v.-irradiated virus, investigation of the mechanism of inhibition of host cell protein synthesis indicates that synthesis of new virus components is required for inhibition to occur. Quantitative comparison of the proteins synthesized in infected cells shows that at higher m.o.i. synthesis of virus, as well as cellular proteins, is inhibited. Bunyamwera virus-infected Vero cells synthesized three virus-specific proteins identified as the structural virion proteins. Nucleoprotein is synthesized predominantly early in infection while the major envelope glycoprotein and the minor glycoprotein are synthesized predominantly late in the infection cycle. (+info)A reassortant bunyavirus isolated from acute hemorrhagic fever cases in Kenya and Somalia. (6/101)
In late 1997 and early 1998, a large outbreak of hemorrhagic fever occurred in East Africa. Clinical samples were collected in Kenya and southern Somalia, and 27 of 115 (23%) hemorrhagic fever patients tested showed evidence of acute infection with Rift Valley fever (RVF) virus as determined by IgM detection, virus isolation, detection of virus RNA by reverse transcription-polymerase chain reaction (RT-PCR), or immunohistochemistry. However, two patients (one from Kenya and the other from Somalia) whose illness met the hemorrhagic fever case definition yielded virus isolates that were not RVF. Electron microscopy suggested these two virus isolates were members of the family Bunyaviridae. RT-PCR primers were designed to detect bunyavirus RNA in these samples. Regions of the S and L segments of the two isolates were successfully amplified, and their nucleotide sequences exhibited nearly complete identity with Bunyamwera virus, a mosquito-borne virus not previously associated with severe human disease. Unexpectedly, the virus M segment appeared to be reassorted, as the sequences detected exhibited 32-33% nucleotide and 28% amino acid differences relative to the corresponding M segment sequence of Bunyamwera virus. The association of this reassortant bunyavirus, proposed name Garissa virus, with severe disease is supported by the detection of the virus RNA in acute-phase sera taken from 12 additional hemorrhagic fever cases in the region. (+info)Bunyamwera bunyavirus nonstructural protein NSs counteracts the induction of alpha/beta interferon. (7/101)
Production of alpha/beta interferons (IFN-alpha/beta) in response to viral infection is one of the main defense mechanisms of the innate immune system. Many viruses therefore encode factors that subvert the IFN system to enhance their virulence. Bunyamwera virus (BUN) is the prototype of the Bunyaviridae family. By using reverse genetics, we previously produced a recombinant virus lacking the nonstructural protein NSs (BUNdelNSs) and showed that NSs is a nonessential gene product that contributes to viral pathogenesis. Here we demonstrate that BUNdelNSs is a strong inducer of IFN-alpha/beta, whereas in cells infected with the wild-type counterpart expressing NSs (wild-type BUN), neither IFN nor IFN mRNA could be detected. IFN induction by BUNdelNSs correlated with activation of NF-kappaB and was dependent on virally produced double-stranded RNA and on the IFN transcription factor IRF-3. Furthermore, both in cultured cells and in mice lacking a functional IFN-alpha/beta system, BUNdelNSs replicated to wild-type BUN levels, whereas in IFN-competent systems, wild-type BUN grew more efficiently. These results suggest that BUN NSs is an IFN induction antagonist that blocks the transcriptional activation of IFN-alpha/beta in order to increase the virulence of Bunyamwera virus. (+info)Polymorphism and structural maturation of bunyamwera virus in Golgi and post-Golgi compartments. (8/101)
The Golgi apparatus is the assembly site for a number of complex enveloped viruses. Using high-preservation methods for electron microscopy, we have detected two previously unknown maturation steps in the morphogenesis of Bunyamwera virus in BHK-21 cells. The first maturation takes place inside the Golgi stack, where annular immature particles transform into dense, compact structures. Megalomicin, a drug that disrupts the trans side of the Golgi complex, reversibly blocks transformation, showing that a functional trans-Golgi is needed for maturation. The second structural change seems to take place during the egress of viral particles from cells, when a coat of round-shaped spikes becomes evident. A fourth viral assembly was detected in infected cells: rigid tubular structures assemble in the Golgi region early in infection and frequently connect with mitochondria. In Vero cells, the virus induces an early and spectacular fragmentation of intracellular membranes while productive infection progresses. Assembly occurs in fragmented Golgi stacks and generates tubular structures, as well as the three spherical viral forms. These results, together with our previous studies with nonrelated viruses, show that the Golgi complex contains key factors for the structural transformation of a number of enveloped viruses that assemble intracellularly. (+info)
The transient nature of bunyamwera orthobunyavirus NSs protein expression : effects of increased stability of NSs protein on...
Expression of functional Bunyamwera virus L protein by recombinant vaccinia viruses. | Journal of Virology
Proteins and Glycoproteins Specified by Bunyamwera Virus and by Belmont Virus, a Possible Bunyavirus, in Mammalian Cells |...
British Library EThOS: Impact of interferon β and interferon stimulated gene induction on Bunyamwera virus replication
L - RNA-directed RNA polymerase L - Bunyamwera virus (BUNV) - L gene & protein
Cache Valley virus - Wikipedia
Elongin C Contributes to RNA Polymerase II Degradation by the Interferon Antagonist NSs of La Crosse Orthobunyavirus | Journal...
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Bunyamwera orthobunyavirus
"Bunyamwera virus (BUNV)". Gerrard SR, Li L, Barrett AD, Nichol ST (2004). "Ngari virus is a Bunyamwera virus reassortant that ... Reassortant viruses derived from Bunyamwera orthobunyavirus, such as Ngari virus, have been associated with large outbreaks of ... Bunya: from Bunyamwera, place in Uganda, where type virus was isolated. "ICTV Taxonomy history: Bunyamwera orthobunyavirus" ( ... Bunyamwera orthobunyavirus (BUNV) is a negative-sense, single-stranded enveloped RNA virus. It is assigned to the ...
Bunyamwera
... is where Bunyamwera orthobunyavirus was first isolated, and it also lends its name to that virus' genus ... Bunya: from Bunyamwera, place in Uganda, where type virus was isolated. (CS1: long volume value, Articles with short ... Bunyamwera is a town in Bundibugyo District, Uganda. It lies just outside of Rwenzori Mountains National Park, which is to the ... In the 1950s, Bunyamwera was considered a Konzo spur village, and children there went to primary school in the parish of ...
Orthobunyavirus
Genbank: Bunyamwera virus segment S, complete sequence Genbank: Bunyamwera virus L segment, complete sequence Sakkas H, Bozidis ... the La Crosse virus and the Jamestown Canyon virus are North American species that cause encephalitis in humans. The virus is ... Kascsak RJ, Lyons MJ (October 1977). "Bunyamwera virus. I. The molecular complexity of the virion RNA". Virology. 82 (1): 37-47 ... The name Orthobunyavirus derives from Bunyamwera, Uganda, where the original type species Bunyamwera orthobunyavirus was first ...
Tensaw orthobunyavirus
Evidence that Bunyamwera serogroup viruses in North America are associated with congenital defects such as macrocephaly and ... Coleman PH (1969). "Tensaw virus, a new member of the Bunyamwera arbovirus group from the Southern United States". Am. J. Trop ... Tensaw orthobunyavirus is a virus in the genus Orthobunyavirus of the Bunyamwera arbovirus group, order Bunyavirales. It is ... Chamberlain RW, Sudia WD, Coleman PH (1969). "Isolations of an arbovirus of the Bunyamwera group (Tensaw virus) from mosquitoes ...
Peribunyaviridae
... where the type virus of the genus, Bunyamwera virus, was first isolated. ICTV Report: Peribunyaviridae (Articles with short ... Fulton virus, Khurdun virus, Lakamha virus, largemouth bass bunyavirus, and Eriocheir sinensis bunya-like virus. "Virus ... Its name partially derives from Bunyamwera, Uganda, where the founding species was first isolated. A number of viruses that ... Peribunyaviridae is a family of viruses in the order Bunyavirales. ...
Ngari virus
... (NRIV) is a single-stranded, negative sense, tri-segmented RNA virus. It is a subtype of the Bunyamwera virus (BUNV ... Gerrard, Sonja R.; Li, Li; Barrett, Alan D.; Nichol, Stuart T. (August 2004). "Ngari virus is a Bunyamwera virus reassortant ... Furthermore, the virus has previously been found within goats and sheep in Mauritania. The virus has been reported primarily in ... Humans that are infected by the virus typically develop severe or fatal hemorrhagic fever. Ngari virus was first isolated in ...
Bunyavirales
Bunya: from Bunyamwera, place in Uganda, where type virus was isolated. Smithburn, K. C.; Haddow, A. J.; Mahaffy, A. F. (March ... "Bunyaviridae - Negative Sense RNA Viruses - Negative Sense RNA Viruses (2011)". International Committee on Taxonomy of Viruses ... Jamestown Canyon virus, La Crosse encephalitis virus, Oropouche orthobunyavirus, and Snowshoe hare virus (vector: mosquitoes; ... As precautions Cache Valley virus and Hantavirus research are conducted in BSL-2 (or higher), Rift Valley Fever virus research ...
Batai orthobunyavirus
A closely associated disease is the Bunyamwera virus, which is of the same family and genus as the Batai virus (BATV); it is ... Batai virus is part of a diverse group of arthropod-borne viruses. Classified via the Baltimore scheme, Batai virus is a ... Associated viruses include Crimean-Congo hemorrhagic fever, Bunyamwera orthobunyavirus, and severe fever with thrombocytopenia ... Batai virus is geographically spread throughout Asia and Europe. It has been shown that batai viruses from Japan, Malaysia and ...
Nucleoprotein
Virus genomes (either DNA or RNA) are extremely tightly packed into the viral capsid. Many viruses are therefore little more ... Structurally characterised viral nucleoproteins include influenza, rabies, Ebola, Bunyamwera, Schmallenberg, Hazara, Crimean- ... Baudin, F; Bach, C; Cusack, S; Ruigrok, R W (1994-07-01). "Structure of influenza virus RNP. I. Influenza virus nucleoprotein ... Some viruses are simple ribonucleoproteins, containing only one molecule of RNA and a number of identical protein molecules. ...
Anhembi orthobunyavirus
... is a species of virus. It was initially considered a strain of Wyeomyia virus, belonging serologically to the Bunyamwera ... Until 2001 this virus has not been reported to cause disease in humans. Lambert, Amy J.; et al. (6 June 2018). "Thirty-eight ... new species within the genus Orthobunyavirus". International Committee on Taxonomy of Viruses (ICTV). Retrieved 3 March 2020. ... Anhembi orthobunyavirus, also called Anhembi virus (AMBV), ...
Fort Sherman virus
... tri-segmented RNA virus. The virus is an isolate of Bunyamwera virus (BUNV) and closely related to Cache Valley virus (CVV). ... Countries containing the virus include Panama, Brazil, and Argentina. Fort Sherman virus was first isolated in 1985 by Joseph A ... Fort Sherman virus is found in a geographic range of more than 7,000 km, solely in South America. ... This was found while analyzing the M segment of the virus in which the Brazil and Argentina strains closely matched while the ...
Lokern virus
... (LOKV) is a single-stranded, negative sense, tri-segmented RNA virus. It is a subtype of the Bunyamwera virus ( ... The virus has been poorly studied and the effects of the virus on humans is currently unknown. Antibodies have been found ... "ArboCat Virus: Lokern (LOKV)". wwwn.cdc.gov. Retrieved 2022-01-09. "ArboCat Virus: Lokern (LOKV)". wwwn.cdc.gov. Retrieved 2022 ... "ArboCat Virus: Lokern (LOKV)". wwwn.cdc.gov. Retrieved 2022-01-09. "ArboCat Virus: Lokern (LOKV)". wwwn.cdc.gov. Retrieved 2022 ...
Aedes furcifer
Yellow fever, chikungunya, Zika, Bouboui and Bunyamwera viruses have been isolated from members of the furcifer group. Ae. ... Diallo, D; Sall, AA; Diagne, CT; Faye, O; Faye, O; Ba, Y; Hanley, KA; Buenemann, M; Weaver, SC; Diallo, M (2014). "Zika virus ... furcifer is involved in monkey-to-man and man-to-man transmission of yellow fever, is a potential vector of dengue virus ... Jupp, PG; McIntosh, BM (1990). "Aedes furcifer and other mosquitoes as vectors of chikungunya virus at Mica, northeastern ...
Cache Valley orthobunyavirus
However, CVVs Bunyamwera serogroup's two non-structural proteins play an important role in infection. Bunyamwera virus (BUNV) ... and Hawaii for antibodies to Cache Valley and antigenically related viruses (Bunyamwera serogroup virus)". Am J Trop Med Hyg. ... a teratogenic virus of the genus Orthobunyavirus closely related to Cache Valley virus, the virus was shown to replicate in the ... Bunyamwera virus NSs protein is a nonessential gene that contributes to viral pathogenesis. It has been shown that in mammalian ...
Alexander John Haddow
In 1942, Haddow joined the Virus Research Institute at Entebbe, Uganda (now known as the Uganda Virus Research Institute) as a ... Bunyamwera and West Nile. In 1961, a steel tower was erected in the Zika forest to allow mosquitoes to be caught simultaneously ... including the discovery of the Zika virus, and research into the insect vectors of the yellow fever virus. Other notable work ... The Zika virus has since emerged as an important human disease, but it was not considered so until very recently. Haddow was ...
Eretmapodites
... and Bunyamwera viruses and an undefined viral agent, MTMP 131. Species listed by the Walter Reed Biosystematics Unit: ... Viruses isolated from wild-caught Eretmapodites include Rift Valley fever, Semliki forest, Spondweni, Nyando, Okola, Middleburg ...
Maguari orthobunyavirus
Bunyamwera serogroup virus may exist in south Florida. U.S. Centers for Disease Control and Prevention: "Virus Name: Maguari" ... MAGV is related to Cache Valley virus and Tensaw virus. In addition to humans, MAGV has been isolated from mosquitoes, horses, ... Human infections with Tensaw virus in south Florida: evidence that Tensaw virus subtypes stimulate the production of antibodies ... The presence of antibodies to Maguari virus in human residents of south Florida can be attributed to either cross-reactivity ...
Aedes aegypti
Aino virus (AINOV), African horse sickness virus (AHSV), Bozo virus (BOZOV), Bussuquara virus (BSQV), Bunyamwera virus (BUNV), ... Kunjin virus (KUNV), La Crosse virus (LACV), Mayaro virus (MAYV), Marburg virus (MBGV), Marco virus (MCOV), Melao virus (MELV) ... Nola virus (NOLV), Ntaya virus (NTAV), Oriboca virus (ORIV), Orungo virus (ORUV), Restan virus (RESV), Rift Valley fever virus ... West Nile virus (WNV), Wesselsbron virus (WSLV), Yaounde virus (YAOV) Yellow fever virus (YFV), Zegla virus (ZEGV), Zika virus ...
Index of Uganda-related articles
Uganda Bunamwaya SC Bundibugyo Bundibugyo Airport Bundibugyo District Bundibugyo ebolavirus Bundibugyo virus Bunyamwera virus ... Kichwamba Uganda-United States relations Uganda Virus Research Institute Uganda Wildlife Authority Uganda women's national ... Acii Oliver Wonekha Olwiyo Omara Atubo Omubanda Omukama of Bunyoro Omukama of Toro Omukuli Onegi Obel O'nyong'nyong virus ... Yasser Mugerwa Youth in Uganda Yoweri Museveni Yumbe Yumbe District Yunus Sentamu Yusuf Lule Zerubabel Nyiira Zika virus ...
Arbovirus
Genus Orthobunyavirus Bunyamwera virus California encephalitis virus Jamestown Canyon virus La Crosse encephalitis virus Genus ... Louis encephalitis virus West Nile virus Spondweni virus group Spondweni virus Zika virus Yellow fever virus group Yellow fever ... virus Tick-borne viruses Mammalian tick-borne virus group Kyasanur forest disease virus Tick-borne encephalitis virus Family ... Dengue virus group Dengue virus Japanese encephalitis virus group Japanese encephalitis virus Murray Valley encephalitis virus ...
Abras orthobunyavirus
"Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 25 May 2021. Mahy, ... Bunyamwera, Patois, and Minatitlan". The American Journal of Tropical Medicine and Hygiene. 32 (4): 877-85. doi:10.4269/ajtmh. ... Abras orthobunyavirus, also called Abras virus (ABRV), is a species of virus in the genus Orthobunyavirus. Isolated from Culex ...
List of MeSH codes (B04)
... bunyamwera virus MeSH B04.820.087.640.300 - encephalitis virus, california MeSH B04.820.087.640.300.500 - la crosse virus MeSH ... yellow fever virus MeSH B04.820.250.400 - gb virus a MeSH B04.820.250.405 - gb virus b MeSH B04.820.250.410 - GB virus C MeSH ... nairobi sheep disease virus MeSH B04.909.777.147.640 - orthobunyavirus MeSH B04.909.777.147.640.147 - bunyamwera virus MeSH ... yellow fever virus MeSH B04.909.777.310.400 - gb virus a MeSH B04.909.777.310.405 - gb virus b MeSH B04.909.777.310.410 - GB ...
List of Aedes species
... carries Bunyamwera virus, California encephalitis virus, Eastern equine encephalitis, Jamestown Canyon virus, Sindbis virus, ... carries California encephalitis virus, Keystone virus, trivittatus virus, West Nile virus, Western equine encephalitis Aedes ... Ross River virus, West Nile virus, Yellow Fever, Zika virus Aedes africanus Aedes albolineatus Aedes alboniveus Aedes ... Louis encephalitis Aedes esoensis Aedes fulvus Bites humans, carries Venezuelan equine encephalitis virus, West Nile virus ...
Emerging infectious disease
Gerrard, Sonja R.; Li, Li; Barrett, Alan D.; Nichol, Stuart T. (2004-08-15). "Ngari Virus Is a Bunyamwera Virus Reassortant ... Omsk Hemorrhagic Fever virus, Alkhurma virus, Kyasanur Forest virus (reclassified from B to C) Powassan virus (Deer Tick virus ... Nipah virus Rabies SARS coronavirus Tick-borne encephalitis virus Tick-borne hemorrhagic fever viruses Other hantaviruses Other ... Junin virus, Machupo virus, Guanarito virus, Lassa fever Bunyaviruses: Hantaviruses, Rift Valley Fever, Crimean-Congo ...
ArboCat Virus: Bunyamwera (BUNV)
Virus Sections. Virus Name/Prototype. Original Source. Method of Isolation. Virus Properties. Antigenic Relationship. Biologic ... Arthropod species & virus source(a) Method of Infection log10/ml (b) Incubation period (c) Transmision by bite (d) Assay of ... Click on the PDF icon to the left to view a copy of this virus entry in PDF format. You can get a copy of the PDF viewer by ... transmission to mice by virus-fed Ae aegypti (33). ... Virus Name: Bunyamwera Abbreviation: BUNV Status. Arbovirus ...
Bunyamwera virus | Harvard Catalyst Profiles | Harvard Catalyst
"Bunyamwera virus" by people in Harvard Catalyst Profiles by year, and whether "Bunyamwera virus" was a major or minor topic of ... "Bunyamwera virus" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Below are the most recent publications written about "Bunyamwera virus" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Bunyamwera virus". ...
ArboCat Virus: Cache Valley (CVV)
Bunyamwera. #section tr td {vertical-align:text-top; height:28px;} #isolation tr td {text-align:center;} Section VII - Natural ... Virus Sections. Virus Name/Prototype. Original Source. Method of Isolation. Virus Properties. Antigenic Relationship. Biologic ... Click on the PDF icon to the left to view a copy of this virus entry in PDF format. You can get a copy of the PDF viewer by ...
ArboCat Virus: Calovo (CVOV)
Bunyamwera. #section tr td {vertical-align:text-top; height:28px;} #isolation tr td {text-align:center;} Section IX - ... Virus Sections. Virus Name/Prototype. Original Source. Method of Isolation. Virus Properties. Antigenic Relationship. Biologic ... Arthropod species & virus source(a) Method of Infection log10/ml (b) Incubation period (c) Transmision by bite (d) Assay of ... Click on the PDF icon to the left to view a copy of this virus entry in PDF format. You can get a copy of the PDF viewer by ...
Table 2 - Lack of Evidence for Zoonotic Transmission of Schmallenberg Virus - Volume 18, Number 11-November 2012 - Emerging...
Ngari virus is a Bunyamwera virus reassortant that can be associated with large outbreaks of hemorrhagic fever in Africa. J ... Snowshoe hare virus. North America, Far-Eastern Europe. Lagomorphs, rodents. Yes. Serology, case reports. Febrile illness. NR. ... California encephalitis virus. North America. Rodents, lagomorphs. Yes. Endemic, common. Febrile illness, encephalitis. NR. (31 ... Iquitos virus. South America. Humans, unknown. Yes. Unexplained fever surveillance. Febrile illness, arthralgia, diarrhea. NR. ...
Are North American Bunyamwera serogroup viruses etiologic agents of human congenital defects of the central nervous system?
Bunyamwera Virus Bunyaviridae Infections Disease Outbreaks Female Head Humans Infant, Newborn Microcephaly Neutralization Tests ... Are North American Bunyamwera serogroup viruses etiologic agents of human congenital defects of the central nervous system?. ... Are North American Bunyamwera serogroup viruses etiologic agents of human congenital defects of the central nervous system? ... Title : Are North American Bunyamwera serogroup viruses etiologic agents of human congenital defects of the central nervous ...
Digoxin is a potent inhibitor of Bunyamwera virus infection in cell culture. | J Gen Virol;104(4)2023 04. | MEDLINE
In this work, we have tested the antiviral capacity of four repurposed drugs to treat Bunyamwera virus (BUNV) infection in cell ... Bunyamwera virus; Bunyavirus; Na+/K+ATPase; antiviral; cell cycle; digoxin; drug repurposing; mitochondria ... Vírus Bunyamwera; Humanos; Animais; Chlorocebus aethiops; Vírus Bunyamwera/genética; Células Vero; Digoxina/farmacologia; ... Digoxin is a potent inhibitor of Bunyamwera virus infection in cell culture. ...
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Links and References | Cache Valley virus | CDC
Information on Cache Valley virus. Provided by Centers for Disease Control and Prevention ... Isolation of Bunyamwera serogroup viruses (Bunyaviridae, Orthobunyavirus) in New York state. J Med Entomol 2006;43:1004-9. ... Reassortant Cache Valley virus associated with acute febrile, non-neurologic illness, Missouri. Clin Infect Dis. 2021; In press ... Fatal Cache Valley virus meningoencephalitis associated with rituximab maintenance therapy. Am J Hematol 2018;93:590-4. ...
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Zika Virus Guidelines: Guidelines Summary, Zika Virus Testing, Preconception and Pregnancy
Bunyamwera, Ntaya, Uganda S and Zika viruses. Trans R Soc Trop Med Hyg. 1953 Jan. 47 (1):13-48. [QxMD MEDLINE Link]. ... Zika Virus Testing. The CDC offers the following recommendations for Zika virus testing in non-pregnant patients [32] :. * Zika ... Testing for evidence of Zika virus infection should be performed in persons with possible exposure to Zika virus who have 1 or ... Evasion of Innate and Intrinsic Antiviral Pathways by the Zika Virus. Viruses. 2019 Oct 22. 11(10):970. [QxMD MEDLINE Link]. ...
First Documentation of Human Crimean-Congo Hemorrhagic Fever, Kenya - Volume 8, Number 9-September 2002 - Emerging Infectious...
... and Bunyamwera serogroup bunyaviruses were also negative. RT-PCR for Crimean-Congo hemorrhagic fever virus (C-CHFV) was ... Johnson BK, Ocheng D, Gichogo A, Okiro M, Libondo D, Tukei PM, Antibodies against haemorrhagic fever viruses in Kenya ... C-CHFV is a tick-borne virus of the genus Nairovirus, family Bunyaviridae, and is widely distributed throughout eastern Europe ... Virus isolation attempts were then terminated because the cultivation of C-CHFV (the presumptive cause) requires biosafety ...
Inkoo and Sindbis viruses in blood sucking insects, and a serological study for Inkoo virus in semi-domesticated Eurasian...
... and Snowshoe hare virus (SSHV). The occurrence and prevalence of INKV in BSI and the high seroprevalence against the virus ... virus circulating in Norway, Sweden, Finland, and some parts of Russia. These viruses are associated with morbidity in humans. ... There has been an upsurge in the number of mosquito-borne viruses in Europe, mostly belonging to the families Togaviridae, ... It is therefore essential to monitor both viruses in the human population. Our findings are important to raise awareness ...
MH DELETED MN ADDED MN
Bunyamwera virus B4.909.777.147.640.147 Bunyaviridae B4.909.777.147 Burkitt Lymphoma C4.557.386.480.100 C4.619.935.313.165 ... GB virus A B4.909.777.310.400 GB virus B B4.909.777.310.475.405 GB virus C B4.909.777.310.410 Gemella B3.353.500.310 Gene ... Hepatitis A virus B4.909.777.618.400.410 Hepatitis A Virus, Human B4.909.777.618.400.410.500 Hepatitis B virus B4.909.204.340. ... Influenza A virus B4.909.777.545.405.400 Influenza A Virus, H10N7 Subtype B4.909.777.545.405.400.920 Influenza A Virus, H10N8 ...
Find Research outputs
- UTMB Health Research Expert Profiles
Morphologic and morphogenetic similarities of Bunyamwera serologic supergroup viruses and several other arthropod-borne viruses ... Herpes simplex virus latency in SV40 hamster tumour cells. Boldogh, I., Geder, L. & Vaczi, L., Dec 1 1973, In: Acta ... Effects of actinomycin D and ultraviolet and ionizing radiation on Pichinde virus. Carter, M. F., Murphy, F. A., Brunschwig, J ... I. Serological identification of Saint Louis encephalitis virus soluble antigens.. Qureshi, A. A. & Trent, D. W., Feb 1 1973, ...
Molecular epidemiology of mosquito-borne viruses at the China-Myanmar border: discovery of a potential epidemic focus of...
Fifteen Japanese encephalitis virus (JEV) strains from Cx. tritaeniorhynchus pools were detected. Seven strains of insect- ... and infection rates of virus and parasite, and further analyze their genotypes, phylogenetic relationships, infection rate, and ... Mosquito-based arbovirus surveillance can serve as an early warning in evaluating the status of mosquito-borne virus prevalence ... Detecting bunyaviruses of the Bunyamwera and California serogroups by a PCR technique. J Clin Microbiol. 1996;34:1184-8. ...
DeCS 2002 - Changed terms
AKR VIRUS. AKR MURINE LEUKEMIA VIRUS. BUNYAMWERA GROUP VIRUSES. BUNYAMWERA VIRUS. CALIFORNIA GROUP VIRUSES. ENCEPHALITIS VIRUS ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... GASTROENTERITIS VIRUS, PORCINE TRANSMISSIBLE. TRANSMISSIBLE GASTROENTERITIS VIRUS. HARVEY SARCOMA VIRUS. HARVEY MURINE SARCOMA ...
DeCS 2002 - Changed terms
AKR VIRUS. AKR MURINE LEUKEMIA VIRUS. BUNYAMWERA GROUP VIRUSES. BUNYAMWERA VIRUS. CALIFORNIA GROUP VIRUSES. ENCEPHALITIS VIRUS ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... GASTROENTERITIS VIRUS, PORCINE TRANSMISSIBLE. TRANSMISSIBLE GASTROENTERITIS VIRUS. HARVEY SARCOMA VIRUS. HARVEY MURINE SARCOMA ...
DeCS 2002 - Changed terms
AKR VIRUS. AKR MURINE LEUKEMIA VIRUS. BUNYAMWERA GROUP VIRUSES. BUNYAMWERA VIRUS. CALIFORNIA GROUP VIRUSES. ENCEPHALITIS VIRUS ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... GASTROENTERITIS VIRUS, PORCINE TRANSMISSIBLE. TRANSMISSIBLE GASTROENTERITIS VIRUS. HARVEY SARCOMA VIRUS. HARVEY MURINE SARCOMA ...
Code System Concept
DeCS 2002 - Changed terms
AKR VIRUS. AKR MURINE LEUKEMIA VIRUS. BUNYAMWERA GROUP VIRUSES. BUNYAMWERA VIRUS. CALIFORNIA GROUP VIRUSES. ENCEPHALITIS VIRUS ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... GASTROENTERITIS VIRUS, PORCINE TRANSMISSIBLE. TRANSMISSIBLE GASTROENTERITIS VIRUS. HARVEY SARCOMA VIRUS. HARVEY MURINE SARCOMA ...
DeCS 2002 - Changed terms
AKR VIRUS. AKR MURINE LEUKEMIA VIRUS. BUNYAMWERA GROUP VIRUSES. BUNYAMWERA VIRUS. CALIFORNIA GROUP VIRUSES. ENCEPHALITIS VIRUS ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... GASTROENTERITIS VIRUS, PORCINE TRANSMISSIBLE. TRANSMISSIBLE GASTROENTERITIS VIRUS. HARVEY SARCOMA VIRUS. HARVEY MURINE SARCOMA ...
DeCS
Batai virus. Bunyamwera Group Viruses. Cache Valley virus. Calovo virus. Chittoor virus. ... virus Batai virus Chittoor virus calovo virus de Cache Valley Scope note:. Especie del género BUNYAVIRUS de la familia ... Bunyamwera virus - Preferred Concept UI. M0003037. Scope note. A species in the ORTHOBUNYAVIRUS genus of the family ... 2002; see BUNYAMWERA VIRUS GROUP 1991-2001, see BUNYAVIRIDAE 1981-1990, see ARBOVIRUSES 1975-80. ...
DeCS 2002 - Changed terms
AKR VIRUS. AKR MURINE LEUKEMIA VIRUS. BUNYAMWERA GROUP VIRUSES. BUNYAMWERA VIRUS. CALIFORNIA GROUP VIRUSES. ENCEPHALITIS VIRUS ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... GASTROENTERITIS VIRUS, PORCINE TRANSMISSIBLE. TRANSMISSIBLE GASTROENTERITIS VIRUS. HARVEY SARCOMA VIRUS. HARVEY MURINE SARCOMA ...
DeCS 2002 - Changed terms
AKR VIRUS. AKR MURINE LEUKEMIA VIRUS. BUNYAMWERA GROUP VIRUSES. BUNYAMWERA VIRUS. CALIFORNIA GROUP VIRUSES. ENCEPHALITIS VIRUS ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... GASTROENTERITIS VIRUS, PORCINE TRANSMISSIBLE. TRANSMISSIBLE GASTROENTERITIS VIRUS. HARVEY SARCOMA VIRUS. HARVEY MURINE SARCOMA ...
DeCS 2002 - Changed terms
AKR VIRUS. AKR MURINE LEUKEMIA VIRUS. BUNYAMWERA GROUP VIRUSES. BUNYAMWERA VIRUS. CALIFORNIA GROUP VIRUSES. ENCEPHALITIS VIRUS ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... SIMBU GROUP VIRUSES. SIMBU VIRUS. SWINE INFERTILITY AND RESPIRATORY SYNDROME VIRUS. PORCINE RESPIRATORY AND REPRODUCTIVE ... GASTROENTERITIS VIRUS, PORCINE TRANSMISSIBLE. TRANSMISSIBLE GASTROENTERITIS VIRUS. HARVEY SARCOMA VIRUS. HARVEY MURINE SARCOMA ...
SerogroupBunyaviridaeOrthobunyavirusInfectionSerologicBUNVViralDescriptorIsolationHumanosCache ValleyClosely relatedMosquito-borne virusesOutbreaksSingle-stranded RNA virusReplicationHumansPrevalenceMosquitoesSpeciesAfricaFebrileFeverMarburgInkooSchmallenbergInfectionsBirdsZIKVAedesMycoplasmaCORONAVIRUSGenomeTransmissionHumanHostsLack of EvidenceSerumGenotypesBarriers
Serogroup5
- Human infections with Tensaw virus in south Florida: evidence that Tensaw virus subtypes stimulate the production of antibodies reactive with closely related Bunyamwera serogroup viruses. (harvard.edu)
- Are North American Bunyamwera serogroup viruses etiologic agents of human congenital defects of the central nervous system? (cdc.gov)
- Isolation of Bunyamwera serogroup viruses (Bunyaviridae, Orthobunyavirus) in New York state. (cdc.gov)
- Serologic tests in Nairobi were negative for yellow fever, dengue, West Nile, Chikungunya, and Rift Valley fever (immunoglobulin [Ig] M-capture enzyme-linked immunosorbent assay) and reverse transcriptase-polymerase chain reaction (RT-PCR) tests for flaviviruses, alphaviruses, and Bunyamwera serogroup bunyaviruses were also negative. (cdc.gov)
- INKV, a member of the California serogroup together with TAHV and Snowshoe hare virus (SSHV), is an enveloped virus belonging to the genus Orthobunyavirus in the Peribunyaviridae family with a tri-segmented, negative-sense, single-stranded (ss) 12.4-kb (kilo-base pair) RNA genome [ 12 ]. (biomedcentral.com)
Bunyaviridae2
- C-CHFV is a tick-borne virus of the genus Nairovirus , family Bunyaviridae, and is widely distributed throughout eastern Europe and the Crimea, to the Middle East and western China, Pakistan, and Africa. (cdc.gov)
- A genus of the family BUNYAVIRIDAE containing over 150 viruses, most of which are transmitted by mosquitoes or flies. (ucdenver.edu)
Orthobunyavirus3
- Viperin, MTAP44, and protein kinase R contribute to the interferon-induced inhibition of Bunyamwera Orthobunyavirus replication. (harvard.edu)
- The N-terminus of Bunyamwera orthobunyavirus NSs protein is essential for interferon antagonism. (harvard.edu)
- The virus, named novel orthobunyavirus, in ruminants in Europe triggered a Schmallenberg virus (SBV), was isolated from blood of joint veterinary and public health response to address the affected cattle, and similar clinical manifestations were possible consequences to human health. (cdc.gov)
Infection13
- van den Brom R , Luttikholt SJ , Lievaart-Peterson K , Peperkamp NH , Mars MH , van der Poel WH , Epizootic of ovine congenital malformations associated with Schmallenberg virus infection. (cdc.gov)
- Digoxin is a potent inhibitor of Bunyamwera virus infection in cell culture. (bvsalud.org)
- In this work , we have tested the antiviral capacity of four repurposed drugs to treat Bunyamwera virus (BUNV) infection in cell cultures . (bvsalud.org)
- Life-threatening Cache Valley virus infection. (cdc.gov)
- Pregnant women with male sex partners who live in or have traveled to an area with active Zika virus transmission should use barriers against infection during sex or abstain from sex for the duration of the pregnancy. (medscape.com)
- For specimens collected from 7 days to 12 weeks after onset of symptoms, a negative IgM antibody result to Zika virus rules out recent infection with either virus, and testing for other etiologies should be considered. (medscape.com)
- If Zika virus IgM antibody testing is positive without a positive NAAT,a plaque reduction neutralization test (PRNT) titer ≥10 against Zika virus with negative PRNTs against dengue and other flaviviruses is evidence of recent Zika virus infection. (medscape.com)
- In most cases, Zika virus infection causes a mild, self-limited illness. (medscape.com)
- 5] Since 2017, Zika cases have declined, and as of January 2021, no countries in the world report active Zika virus infection outbreaks. (medscape.com)
- Zika virus infection is among the nationally notifiable diseases in the United States since 2016. (medscape.com)
- It is speculated that Zika virus Asian lineage is associated with serious outbreaks and congenital malformations and that African lineage is intrinsically more virulent and is associated with acute infection and adverse pregnancy outcomes. (medscape.com)
- 6 ). The teratogenic effects in ruminants are hypothesized to In November 2011, scientists in Germany identifi ed novel refl ect virus circulation in late summer/early autumn 2011, viral sequences in serum from cattle affected by a febrile leading to intrauterine infection with SBV during a specifi c syndrome that was reported during August-September 2011 period of gestation ( 4 ). (cdc.gov)
- Samples collected from 342 pools were tested using reverse-transcription PCR to determine the species, distribution, and infection rates of virus and parasite, and further analyze their genotypes, phylogenetic relationships, infection rate, and potential pathogenicity. (biomedcentral.com)
Serologic1
- A newly recognized vesiculovirus, Calchaqui virus, and subtypes of Melao and Maguari viruses from Argentina, with serologic evidence for infections of humans and horses. (harvard.edu)
BUNV1
- BUNV is the prototype of the Bunyavirales order, a large group of RNA viruses that includes important pathogens for humans , animals and plants . (bvsalud.org)
Viral3
- A novel cause of chronic viral meningoencephalitis: Cache Valley virus. (cdc.gov)
- 10] Studies have demonstrated inhibition of stress granule formation and modulation of nonsense-mediated mRNA decay machinery by Zika virus, enhancing its viral replication. (medscape.com)
- This historical isolate, Ukauwa virus is preserved under Viral Storage Medium -80C. (european-virus-archive.com)
Descriptor1
- Bunyamwera virus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
Isolation2
- Virus isolation attempts were then terminated because the cultivation of C-CHFV (the presumptive cause) requires biosafety level 4 facilities. (cdc.gov)
- No isolation of the virus could be made from the serum sample, possibly because it was received by the Johannesburg laboratory 8 days after initial collection and following freeze-thaw conditions. (cdc.gov)
Humanos1
- Se transmiten por mosquitos e infectan a los humanos en algunas áreas. (bvsalud.org)
Cache Valley10
- Cross-neutralization tests among Cache Valley virus isolates revealing the existence of multiple subtypes. (harvard.edu)
- Reassortant Cache Valley virus associated with acute febrile, non-neurologic illness, Missouri. (cdc.gov)
- Fatal Cache Valley virus meningoencephalitis associated with rituximab maintenance therapy. (cdc.gov)
- Cache valley virus in a patient diagnosed with aseptic meningitis. (cdc.gov)
- Second human case of Cache Valley virus disease. (cdc.gov)
- Cache Valley virus is spread to people by the bite of an infected mosquito. (cdc.gov)
- Cache Valley virus has been found in many types of mosquitoes, but it is not known which species are the main ones that spread the virus to humans. (cdc.gov)
- As a result, people are considered "dead-end" hosts for Cache Valley virus. (cdc.gov)
- Cache Valley virus is not spread by coughing, sneezing, touching, or other contact with someone who is infected. (cdc.gov)
- Prevent getting infected with Cache Valley virus by preventing mosquito bites . (cdc.gov)
Closely related1
- Of the 60 reindeer sera- analysed by PRNT for INKV, 80% were confirmed positive, and there was no cross-reactivity with the closely related Tahyna virus (TAHV) and Snowshoe hare virus (SSHV). (biomedcentral.com)
Mosquito-borne viruses4
- Mosquito-borne viruses pose a serious threat to humans worldwide. (biomedcentral.com)
- Our findings are important to raise awareness regarding the geographical distribution of these mosquito-borne viruses in Northern Europe. (biomedcentral.com)
- Surveillance of mosquito-borne viruses and their prevalence in the human and animal populations is highly required, since INKV, SINV, Chikungunya virus and West Nile virus infections often are not reported and remain undiagnosed [ 2 ]. (biomedcentral.com)
- The prevalence of mosquito-borne viruses is rising steeply with increasing frequency of international trade and travel. (biomedcentral.com)
Outbreaks2
- Mosquito-based arbovirus surveillance can serve as an early warning in evaluating the status of mosquito-borne virus prevalence and thus prevent local outbreaks. (biomedcentral.com)
- Two strains of the virus have caused outbreaks of severe respiratory diseases in humans: severe acute respiratory syndrome coronavirus 1 (SARS-CoV or SARS-CoV-1), which caused the 2002-2004 outbreak of severe acute respiratory syndrome (SARS), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is causing the ongoing pandemic of COVID-19 . (wikizero.com)
Single-stranded RNA virus1
- The SARS-related coronavirus is an enveloped, positive-sense, single-stranded RNA virus . (wikizero.com)
Replication1
- 10] Activation of type I interferon (IFN) and IFN-stimulated genes (ISG) inhibits Zika virus replication. (medscape.com)
Humans3
- These viruses are associated with morbidity in humans. (biomedcentral.com)
- Argentinean hemorrhagic f. a form of hemorrhagic f. observed in South America, seemingly transmitted by contact from rodents to humans and caused by the Junin virus , a member of the family Arenaviridae. (en-academic.com)
- Severe acute respiratory syndrome-related coronavirus ( SARSr-CoV or SARS-CoV ) [note 1] is a species of virus consisting of many known strains phylogenetically related to severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1) that have been shown to possess the capability to infect humans , bats , and certain other mammals . (wikizero.com)
Prevalence1
- The occurrence and prevalence of INKV in BSI and the high seroprevalence against the virus among semi-domesticated reindeer in Norway indicate that further studies are required for monitoring this virus. (biomedcentral.com)
Mosquitoes5
- Mosquitoes that spread Zika virus usually do not live at elevations above 6,500 feet (2,000 meters). (medscape.com)
- Mosquitoes which transmit clinically relevant viruses in China include Aedes albopictus , Culex tritaeniorhynchus , and Anopheles sinensis as the dominant species in several areas, mainly transmitting dengue virus (DENV), Japanese encephalitis virus (JEV), and Plasmodium spp. (biomedcentral.com)
- Mosquitoes become infected when they feed on mammals that have the virus in their blood. (cdc.gov)
- Infected mosquitoes can then spread the virus to people and other animals by biting them. (cdc.gov)
- People do not develop high enough levels of the virus in their blood to infect mosquitoes and further spread the disease. (cdc.gov)
Species2
- 9 ). The orthobunyaviruses comprise 170 virus isolates, cohorts were not available because SBV is a novel emerging assigned to 48 distinct species, arranged in 18 serogroups, virus with unknown zoonotic potential. (cdc.gov)
- [4] The SARSr-CoV species is a member of the genus Betacoronavirus and of the subgenus Sarbecovirus ( SAR S Be ta co rona virus ). (wikizero.com)
Africa1
- 1, 2] Zika virus is widely distributed outside Africa. (medscape.com)
Febrile1
- Zika virus was first described in a captive sentinel febrile rhesus monkey in the Zika forest of Entebbe, Uganda in 1947. (medscape.com)
Fever1
- RT-PCR for Crimean-Congo hemorrhagic fever virus (C-CHFV) was positive. (cdc.gov)
Marburg1
- African hemorrhagic f. hemorrhagic f. associated with the morphologically similar but antigenically distinct Marburg and Ebola viruses as well as numerous other viruses that cause similar diseases. (en-academic.com)
Inkoo1
- The principal focus of this study was Inkoo (INKV) and Sindbis (SINV) virus circulating in Norway, Sweden, Finland, and some parts of Russia. (biomedcentral.com)
Schmallenberg5
- Schmallenberg" virus: analysis of the epidemiological data and assessment of impact. (cdc.gov)
- Gariglinay MM , Hoffmann B , Dive M , Sartelet A , Bayrou C , Cassart D , Schmallenberg virus in calf born at term with porencephaly, Belgium. (cdc.gov)
- Bilk S , Schulze C , Fischer M , Beer M , Hlinak A , Hoffmann B , Organ distribution of Schmallenberg virus RNA in malformed newborns. (cdc.gov)
- Schmallenberg virus-Europe (45): Denmark, serological evidence. (cdc.gov)
- The emergence of Schmallenberg virus (SBV), a decreased milk production and diarrhea. (cdc.gov)
Infections2
- 1] The spectrum of Zika virus disease overlaps with other arboviral infections, but rash (maculopapular and likely immune-mediated) typically predominates. (medscape.com)
- 1] Unlike other arboviral infections, Zika virus has potential for sexual transmission[1] and has been associated with congenital brain abnormalities in pregnant women infected during the first trimester. (medscape.com)
Birds1
- Natural hosts for this virus are varied (including wild and domestic animals and birds) and may reflect the feeding preferences of the host tick (1) . (cdc.gov)
ZIKV1
- On May 12, 2021, the US Food and Drug Administration (FDA) stopped recommending that blood establishments test donated blood for Zika virus (ZIKV). (medscape.com)
Aedes1
- In 1948, the virus was recovered from the mosquito Aedes africanus in the Zika forest. (medscape.com)
Mycoplasma1
- The virus is mycoplasma free. (european-virus-archive.com)
CORONAVIRUS1
- The SARS-related coronavirus was one of several viruses identified by the World Health Organization (WHO) in 2016 as a likely cause of a future epidemic in a new plan developed after the Ebola epidemic for urgent research and development before and during an epidemic towards diagnostic tests , vaccines and medicines . (wikizero.com)
Genome2
- The genome of the Zika virus has a length of 10.7 kb, divided into structural and non-structural segments. (medscape.com)
- Its genome is about 30 kb , which is one of the largest among RNA viruses. (wikizero.com)
Transmission2
- Multiplies in Ae canadensis and Ae triseriatus after intrathoracic inoculation, transmission to mice by virus-fed Ae aegypti (33). (cdc.gov)
- Updates on areas with ongoing Zika virus transmission are available online . (medscape.com)
Human2
- Zika virus has tropism for various tissues in the human body such as skin, blood, placenta cells, testes, retinal cells, neural stem cells and neuroprogenitor cells. (medscape.com)
- It is therefore essential to monitor both viruses in the human population. (biomedcentral.com)
Hosts1
- Zika virus is well-adapted to grow in various hosts, ranging from arthropods to vertebrates. (medscape.com)
Lack of Evidence1
- Lack of Evidence for Zoonotic SBV virus segments show the highest sequence identity. (cdc.gov)
Serum1
- Zika virus nucleic acid amplification test (NAAT) should be performed on serum collected ≤7 days after symptom onset. (medscape.com)
Genotypes1
- Zika virus has 2 Zika virus lineages (Asian and African) and 3 genotypes (West African, East African, and Asian) based on phylogenetic analysis. (medscape.com)
Barriers1
- Zika virus also infects monocytes, facilitating passage across blood-brain and placental barriers. (medscape.com)