Bufo bufo
Glycosides
Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)
Bufo marinus
Bufonidae
Cardiac Glycosides
Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
Digitalis Glycosides
Glycosides from plants of the genus DIGITALIS. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all CARDIAC GLYCOSIDES, but here is restricted to those related to Digitalis.
Iridoid Glycosides
Digitoxin
Iridoids
Spectrometry, Mass, Fast Atom Bombardment
A mass spectrometric technique that is used for the analysis of a wide range of biomolecules, such as glycoalkaloids, glycoproteins, polysaccharides, and peptides. Positive and negative fast atom bombardment spectra are recorded on a mass spectrometer fitted with an atom gun with xenon as the customary beam. The mass spectra obtained contain molecular weight recognition as well as sequence information.
Plant Extracts
Cardenolides
C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.
Anura
Ouabain
Iridoid Glucosides
Amphibian Venoms
Venoms produced by frogs, toads, salamanders, etc. The venom glands are usually on the skin of the back and contain cardiotoxic glycosides, cholinolytics, and a number of other bioactive materials, many of which have been characterized. The venoms have been used as arrow poisons and include bufogenin, bufotoxin, bufagin, bufotalin, histrionicotoxins, and pumiliotoxin.
Pregnanes
Digoxin
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
Cimicifuga
Magnetic Resonance Spectroscopy
Rutin
Ranidae
Rhizome
Ranunculaceae
Stevia
Saponins
beta-Glucosidase
Kaempferols
Molecular Structure
Sodium-Potassium-Exchanging ATPase
An enzyme that catalyzes the active transport system of sodium and potassium ions across the cell wall. Sodium and potassium ions are closely coupled with membrane ATPase which undergoes phosphorylation and dephosphorylation, thereby providing energy for transport of these ions against concentration gradients.
Spirostans
Quercetin
Carbohydrate Sequence
Photoreceptor Cells
Specialized cells that detect and transduce light. They are classified into two types based on their light reception structure, the ciliary photoreceptors and the rhabdomeric photoreceptors with MICROVILLI. Ciliary photoreceptor cells use OPSINS that activate a PHOSPHODIESTERASE phosphodiesterase cascade. Rhabdomeric photoreceptor cells use opsins that activate a PHOSPHOLIPASE C cascade.
Asclepias
Vasotocin
Amphibians
Sympatry
Urinary Bladder
Endo-1,4-beta Xylanases
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Plants, Medicinal
Scrophulariaceae
Sugar Alcohols
Cellvibrio
Norisoprenoids
Cellulase
Acid-Base Equilibrium
Sodium
Ranavirus
Chromatography, High Pressure Liquid
Rhodiola
Drugs, Chinese Herbal
Xylosidases
A group of enzymes that catalyze the hydrolysis of alpha- or beta-xylosidic linkages. EC 3.2.1.8 catalyzes the endo-hydrolysis of 1,4-beta-D-xylosidic linkages; EC 3.2.1.32 catalyzes the endo-hydrolysis of 1,3-beta-D-xylosidic linkages; EC 3.2.1.37 catalyzes the exo-hydrolysis of 1,4-beta-D-linkages from the non-reducing termini of xylans; and EC 3.2.1.72 catalyzes the exo-hydrolysis of 1,3-beta-D-linkages from the non-reducing termini of xylans. Other xylosidases have been identified that catalyze the hydrolysis of alpha-xylosidic bonds.
Pituitary Hormones, Posterior
Hormones released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). They include a number of peptides which are formed in the NEURONS in the HYPOTHALAMUS, bound to NEUROPHYSINS, and stored in the nerve terminals in the posterior pituitary. Upon stimulation, these peptides are released into the hypophysial portal vessel blood.
Lamiaceae
Plant Leaves
Substrate Specificity
Microspectrophotometry
Analytical technique for studying substances present at enzyme concentrations in single cells, in situ, by measuring light absorption. Light from a tungsten strip lamp or xenon arc dispersed by a grating monochromator illuminates the optical system of a microscope. The absorbance of light is measured (in nanometers) by comparing the difference between the image of the sample and a reference image.
Acanthaceae
A plant family of the order Lamiales. It is characterized by simple leaves in opposite pairs, cystoliths (enlarged cells containing crystals of calcium carbonate), and bilaterally symmetrical and bisexual flowers that are usually crowded together. The common name for Ruellia of wild petunia is easily confused with PETUNIA.
Potassium
An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
Plant Roots
Oviducts
Cellulases
A family of glycosidases that hydrolyse crystalline CELLULOSE into soluble sugar molecules. Within this family there are a variety of enzyme subtypes with differing substrate specificities that must work together to bring about complete cellulose hydrolysis. They are found in structures called CELLULOSOMES.
Convolvulaceae
Spectrophotometry, Infrared
Rubiaceae
Hydrogen-Ion Concentration
Resins, Plant
Flammable, amorphous, vegetable products of secretion or disintegration, usually formed in special cavities of plants. They are generally insoluble in water and soluble in alcohol, carbon tetrachloride, ether, or volatile oils. They are fusible and have a conchoidal fracture. They are the oxidation or polymerization products of the terpenes, and are mixtures of aromatic acids and esters. Most are soft and sticky, but harden after exposure to cold. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)
Gardenia
Psidium
Cynanchum
Naphthacenes
Methohexital
Amino Acid Sequence
Acari
Picrorhiza
Acanthopanax
Spectrometry, Mass, Electrospray Ionization
A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry.
Vitelline Duct
Vasopressins
Antidiuretic hormones released by the NEUROHYPOPHYSIS of all vertebrates (structure varies with species) to regulate water balance and OSMOLARITY. In general, vasopressin is a nonapeptide consisting of a six-amino-acid ring with a cysteine 1 to cysteine 6 disulfide bridge or an octapeptide containing a CYSTINE. All mammals have arginine vasopressin except the pig with a lysine at position 8. Vasopressin, a vasoconstrictor, acts on the KIDNEY COLLECTING DUCTS to increase water reabsorption, increase blood volume and blood pressure.
Sambucus nigra
Campa C, Schmitt-Kopplin P, Cataldi TR, Bufo SA, Freitag D, Kettrup A (2000). "Analysis of cyanogenic glycosides by micellar ... The seeds and all green parts of the plant contain cyanogenic glycosides. Consumption of berries, leaves, bark or stems, if not ... containing the cyanogenic glycoside sambunigrin (C14H17NO6, CAS number 99-19-4). The bark contains calcium oxalate crystals. It ... and cyanogenic glycosides, which may be toxic if consumed raw. ...
HuaChanSu
... (bufo bufo gargarizans) is a traditional Chinese medicine extracted from the skin of toads from the genus Bufo that ... The molecules in HuaChanSu include the cardiac glycosides bufalin, cinobufagin, cinobufotalin and resibufogenin. These ... Bufo is a group of over 150 species of toads. Nearly all of these species contain a venom in their skin called bufotoxin which ... Bufo toads can live under very adverse conditions resulting in its inhabitance in nearly every continent; its ability to ...
Bufanolide
Its derivatives was found in Bufo and Scilla, as an aglycone of cardiac glycosides and is usually toxic. Tao Song, Yuanyuan ...
Bufotenin
Bufo venoms also contain digoxin-like cardiac glycosides, and ingestion of the venom can be fatal. Ingestion of Bufo toad venom ... Takeda N (February 1994). "Serotonin-degradative pathways in the toad (Bufo bufo japonicus) brain: clues to the pharmacological ... by smoking or orally ingesting Bufo toad venom or dried Bufo skins. The use of chan'su and love stone (a related toad venom ... Bufotenin is found in the poison and eggs of several species of toads belonging to the genus Bufo, but is most concentrated in ...
Bufotalin
Rhinella marina (Cane toad), Rhaebo guttatus (Smooth-sided toad), Bufo melanostictus (Asian toad), and Bufo bufo (common ... Bufotalin is a cardiotoxic bufanolide steroid, cardiac glycoside analogue, secreted by a number of toad species. Bufotalin can ... Bufo bufo gargarizans Canto) venom in guinea-pigs in vivo and in vitro". Toxicology Mechanisms and Methods. 22 (1): 1-8. doi: ...
Bufadienolide
The term derives from the toad genus Bufo that contains bufadienolide glycosides, the suffix -adien- that refers to the two ... These are a type of cardiac glycoside, the other being the cardenolide glycosides. Both bufadienolides and their glycosides are ... Its derivatives are collectively known as bufadienolides, including many in the form of bufadienolide glycosides ( ... Polycyclic compounds Steroids Cardanolides Cardiac glycosides Bufanolides (includes bufenolides, bufadienolides, ...
Bufotoxin
Bufo alvarius Bufo americanus Bufo arenarum Bufo asper Bufo blombergi Bufo boreas Bufo bufo Bufo bufo gargarizans Sclerophrys ... which are cardiac glycosides (e.g., bufotalin, bufogenin) tryptamine-related substances (e.g., bufotenin) Toads known to ... formerly Bufo marinus) Bufo melanostictus Bufo peltocephalus Bufo quercicus Bufo regularis Bufo valliceps Bufo viridis Bufo ... Bufo gutturalis) Bufo formosus Bufo fowleri Rhinella marina ( ... such as Bufo bufo gargarizans and Bufo melanostictus, is often ...
Colorado River toad
Bufo secretions also contain digoxin-like cardiac glycosides, and ingestion of the poison can be fatal. Ingestion of Bufo toad ... by smoking or orally ingesting Bufo toad secretion or dried Bufo skins. The use of chan'su and love stone (a related toad toxin ... Bufo) punctatus and Incilius (Bufo) alvarius". Zoological Science. 28 (9): 664-670. doi:10.2108/zsj.28.664. PMID 21882955. ... Bufo woodhousii) in Central Arizona". Copeia. 1999 (2): 281-286. doi:10.2307/1447473. JSTOR 1447473. "COLORADO RIVER TOAD (Bufo ...
Cardiac glycoside
... "bufo" portion of their name. Below is a list of organisms from which cardiac glycosides can be derived. Convallaria majalis ( ... "Cardiac Glycosides". www.people.vcu.edu. Retrieved 2017-05-25. Cheeke PR (1989-07-31). Toxicants of Plant Origin: Glycosides. ... The general structure of a cardiac glycoside consists of a steroid molecule attached to a sugar (glycoside) and an R group. The ... as done by cardiac glycosides. Nevertheless, due to questions of toxicity and dosage, cardiac glycosides have been replaced ...
Aphrodisiac
Bufotenin is found in the skin and glands of Bufo toads. It is commonly used in West Indian and Chinese cultures. West Indian ... Horny goat weed contains icariin, a flavanol glycoside. Alcohol has been associated as an aphrodisiac due to its effect as a ... Ginseng's active ingredients are ginsenosides and saponin glycosides. There are three different ways to process ginseng. Fresh ... Bufo toad, yohimbine, horny goat weed, ginseng, alcohol, and food are recorded throughout these texts as containing aphrodisiac ...
Arenobufagin
There is a rather large homology in structure between arenobufagin and cardiac glycosides. Cardiac glycosides are natural ... such as the Bufo gargarizans or the Bufo melanostictus Suhneider. Arenobufagin is specifically secreted by the Rhinella ... Structure of Arenobufagin Structure of a Cardiac Glycoside Although a low dosis of arenobufagin can be used as a medicine of ... Arenobufagin is a cardiotoxic bufanolide steroid secreted by the Argentine toad Bufo arenarum. It has effects similar to ...
Duttaphrynus melanostictus
Black-spined Toad (Bufo melanostictus) Risk Assessments for Australia; Department of Agriculture and Food: Western Australia. ... the possibility that some Malagasy animals do possess resistance to bufotenin because almost identical cardiac glycosides are ... Covacevich, Jeanette, and Archer, Mike; 'The distribution of the cane toad, Bufo marinus in Australia and its effects on ... Berry, P. Y.; Bullock, J. A. (1962). "The Food of the Common Malayan Toad, Bufo melanostictus Schneider". Copeia. 1962 (4): 736 ...
Batesian mimicry
5. The Reactions of Toads (Bufo terrestris) to Bumblebees (Bombus americanorum) and Their Robberfly Mimics (Mallophora ... with one being completely potent with regard to cardiac glycoside toxicity, the second not. The first will fit all of the ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Cardiac Glycoside Plant Poisoning: Practice Essentials, Pathophysiology, Etiology
Cardiac glycosides are found in a diverse group of plants including Digitalis purpurea and Digitalis lanata (foxgloves), Nerium ... In addition, the venom gland of cane toad (Bufo marinus) contains large quantities of a purported aphrodisiac substance that ... encoded search term (Cardiac Glycoside Plant Poisoning) and Cardiac Glycoside Plant Poisoning What to Read Next on Medscape ... Cardiac glycosides are found in a diverse group of plants including the following [1] :. * Digitalis purpurea and Digitalis ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Toad venom is prepared from dried secretions, typically from the Asiatic toad (Bufo gargarizans). In addition being an ... contains cardiac glycosides whose structure and biochemical activity are similar to those of digitalis. These cause ...
Sambucus nigra - Wikipedia
Campa C, Schmitt-Kopplin P, Cataldi TR, Bufo SA, Freitag D, Kettrup A (2000). "Analysis of cyanogenic glycosides by micellar ... The seeds and all green parts of the plant contain cyanogenic glycosides. Consumption of berries, leaves, bark or stems, if not ... containing the cyanogenic glycoside sambunigrin (C14H17NO6, CAS number 99-19-4). The bark contains calcium oxalate crystals. It ... and cyanogenic glycosides, which may be toxic if consumed raw. ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Hyperkalemia: Practice Essentials, Background, Pathophysiology
Hyperkalemia: Practice Essentials, Background, Pathophysiology
smoking toad venom youtube
1 The venom gland of cane toad (Bufo marinus) contains large quantities of cardiac glycosides. 1 Dried toad venom is used in ... Bufo alvarius medicine made its way mainstream(ish) out of secrecy in 2011. Using Bufo helps you put ego aside to enable ... BUFO CEREMONY . Science has changed the name Bufo to Ollotis Alvaria but it is still the Colorado toad (inchillius alvarius ). ... Bufo Alvarius, which produces a venom known as 5-MeO-DMT: an extremely. . The Colorado River Toad (Bufo alvarius), also known ...
Cardiac Glycoside Plant Poisoning: Practice Essentials, Pathophysiology, Etiology
Cardiac glycosides are found in a diverse group of plants including Digitalis purpurea and Digitalis lanata (foxgloves), Nerium ... In addition, the venom gland of cane toad (Bufo marinus) contains large quantities of a purported aphrodisiac substance that ... encoded search term (Cardiac Glycoside Plant Poisoning) and Cardiac Glycoside Plant Poisoning What to Read Next on Medscape ... Cardiac glycosides are found in a diverse group of plants including the following [1] :. * Digitalis purpurea and Digitalis ...
Is Kalanchoe Poisonous? (To Humans and Pets) - The Practical Planter
Theyre cardiac glycosides and are present in the plants entire body.. From stem to leaves, this concentrated amount of ... Its interesting to learn that the same poison found in the Kalanchoe family can also be noted in the skin of the Bufo or the ... Not only that, but bufadienolide glycosides attach themselves to units of the myocardium, skeletal muscle, kidney, and red ... How do these various cardiac glycosides affect you once theyre ingested, however? ...
Hyperkalemia: Practice Essentials, Background, Pathophysiology
UMEM Educational Pearls - University of Maryland School of Medicine, Department of Emergency Medicine
Search | Global Index Medicus
Journal name: Journal of ethnopharmacology / Publication Year: 2014 - PubAg Search Results
Antiproliferative activity and new argininyl bufadienolide esters from the "cururú" toad Rhinella (Bufo) schneideri ... Sambucus ebulus; abscess; anti-ulcer activity; bioassays; butanol; chromatography; flavonols; fractionation; glycosides; in ... Bufo; pressing; leukemia; erysipelas; neoplasm cells; spectral analysis; lungs; epithelium; inhibitory concentration 50; ... and two isolated kaempferol glycosides of Carthamus tinctorius L. to provide experimental evidence for its traditional use.An ...
Oznaczanie witaminy B2 i jej pochodnych wybranymi technikami chromatograficznymi - Zeszyty Naukowe / Uniwersytet Ekonomiczny w...
Phyto-factories of anti-cancer compounds: a tissue culture perspective | Beni-Suef University Journal of Basic and Applied...
Benefits of Digoxin | Interstellar Blends | Activate Your Super Powers!
Purpurea Glycoside-A and Purpurea Glycoside-B from Digitalis Seeds.. *Studies on the constituents of DIGITALIS PURPUREA LV On ... Digitalis-like and vasoconstrictor effects of endogenous Digoxin-like factor (s) from the venom of Bufo marinus toad ... Digitalis glycosides. IV. Influence of drying temperature on glycoside composition in Digitalis leaves (D. purpurea and D. ... New Cardiotonic Glycosides, Acetyl-digitoxin-γ and Acetyl-gitoxin-γ.. *Studies on the Constituents of DIGITALIS PURPUREA L. XXI ...
Hinokiflavone | CAS:19202-36-9 | Chengdu Herbpurify CO.,LTD
PHAR204-0315: Common Toxicants by Body System 2015 - Continual Education - VIN
Plasma potassium may protect sodium pumps of toad hearts from an endogenous inhibitor
It is present in the skin of the cane toad (Bufo marinus) at a concentration equivalent to ouabain of ~1 mM. Because toads, ... Resibufogenin (3-hydroxy-14,15-epoxy-20,22-dienolide glycoside) is a potent sodium pump inhibitor present in toad toxin. It is ... Resibufogenin (3-hydroxy-14,15-epoxy-20,22-dienolide glycoside) is a potent sodium pump inhibitor present in toad toxin. ... present in the skin of the cane toad (Bufo marinus) at a concentration equivalent to ouabain of ~1 mM. Because toads, like ...
Erowid.org: References Database
Cyanogenic Glycosides in Plants Brazilian Archives o.... 2000. van Dyck CH, Malison RT, .... Age-related decline in central ... Bufo toads and bufotenine: fact and fiction surrounding an alleged psy... J Psychoactive Drugs. 1996. ... Bufo toads and bufotenine: fact and fiction surrounding an alleged psy... J Psychoactive Drugs. 1996. ...
Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding...
In addition, while some cardiac steroid glycosides (e.g., digoxin), but not the aglycones, display a higher binding affinity ... releases and oxygen consumption rates were also determined in cancer cells treated with these various cardiac glycosides. ... steroid aglycones usually display weaker binding affinity and in vitro anticancer activity than the corresponding glycoside, ... The in vitro growth inhibitory effects of seven cardiac glycosides including five cardenolides (ouabain, digoxin, digitoxin, ...
High purity phytochemicals: Schisandrin, Fraxinellone and Securinine | Chengdu Herbpurify CO.,LTD
cardenolides
cardiac glycosides*nerium*asclepias*ouabain*digitalis*apocynaceae*calotropis*digitoxigenin*antiaris*natriuresis*digitoxin* ... Isolation and characterization of novel endogenous digitalis-like factors in the ovary of the giant toad, Bufo marinus. J Nat ... digitalis glycosides*adonis*dolichol*inbred dahl rats*periploca*celastraceae*hydroxymethylglutaryl coa reductases*aphrodisiacs* ... In this review, we focus on two compound classes, iridoid glycosides and cardenolides, which can be found in the food plants of ...
The Beat | Environmental Health Perspectives | Vol. 116, No. 3
Cardiac glycosides in the venom are thought to inhibit proteins that promote cancer cell growth, thereby causing cancer cell ... Bufo gargarizans). Chinas use of the venom in the treatment of a number of illnesses can be traced back to the tenth century. ... Although potentially toxic at high doses, these glycosides are used to treat congestive heart failure. Currently, the venom- ...
UMEM Educational Pearls - University of Maryland School of Medicine, Department of Emergency Medicine
Keywords: cardioactive steroids, cardioactive glycoside (PubMed Search) Posted: 11/9/2017 by Hong Kim, MD, MPH (Updated: 1/16/ ... Bufo toad (Bufo species) Non-digoxin cardioactive steroid exposure can result in a positive digoxin level due to cross ... There are other sources of cardioactive steroids (aka cardiac glycosides) that have similar effect as digoxin. ...
Amphibian proteins. Medical search
BiologicalBufo arenarumRana pipiensXenopusBufo marinusLarvaMycosesRana catesbeianaPondsAnimal DiseasesNotophthalmus viridescens ... The venom glands are usually on the skin of the back and contain cardiotoxic glycosides, cholinolytics, and a number of other ... The SBPs in Bufo consist exclusively of two protamines (Pl, P2), and those in Xenopus consist of 6 proteins (SPl-6) in addition ... Bufo marinus. A species of the true toads, Bufonidae, becoming fairly common in the southern United States and almost ...
MESH TREE NUMBER CHANGES - 2004 MeSH
D27.720.150 Bufo arenarum B2.90.180.210.80 B1.150.900.90.180.210.80 Bufo bufo B2.90.180.210.108 B1.150.900.90.180.210.108 Bufo ... Digitalis Glycosides D4.808.155.580.261 Digitonin D4.808.155.580.261.236 Digitoxin D4.808.155.580.261.336 Diglycerides D10.516. ... D10.390 Glycoside Hydrolases D8.586.277.450 D8.811.277.450 Glycosphingolipids D10.516.390.470 D10.390.470 D10.516.570.877.360 ... A3.556.875.875.163 Cardiac Glycosides D4.808.155.580 Cardiac Myosins D8.586.277.40.25.525.750.124 D8.811.277.40.25.525.750.124 ...
Search | Global Index Medicus
PMID- 5428627
PMID- 5435508 TI - On the early appearance of arginase activity in the liver of Bufo bufo larvae after prolactin treatment. ... The glycosides of Marsdenia erecta R. Br. I. Isolation, glycoside and aglycone. 325]. PMID- 5435977 TI - [Protonation of amino ... PMID- 5436407 TI - Specific nuclear DNA amounts in toads of the genus Bufo. PMID- 5436409 TI - The "20-minute hour" revisited: ... Leukocyte DNA-synthesis and cell reaction to phytohemagglutinin in cell culture]. PMID- 5436667 TI - [Cardiac glycoside therapy ...
Toad skin disease - the term phrynoderma means toad sk
Bufo alvarius. CARE SHEET. Bufo alvarius toads can live for surprisingly long times. In general, toads will live from about 5 ... Toad secretions contain traces of cardiac glycosides, which is a toxic substance that can lead to deadly consequences. Blister ... Medicinal toad venom is the dried white secretion of the auricular glands and the skin glands of Bufo bufo gargarizans Cantor ... The dried secretion from the auricular and skin glands of Chinese toad ( Bufo bufo gargarizans ) is named Chansu, which has ...
Vitex negundo L. | Chengdu Herbpurify CO.,LTD
Newly made Reference Standards: Gomisin N CAS:69176-52-9 | Chengdu Herbpurify CO.,LTD
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... bufo Bufo Bufo alvarius Bufo americanus Bufo andersonii Bufo arenarum Bufo boreas Bufo boreas halophilus Bufo bufo Bufo bufo ... acrylaldehydes acrylamide acrylamides acrylamido acrylamidoethyl acrylamidoethyl glycoside acrylamidoethyl glycosides acrylate ... Bufo bufo japonicus Bufo bufo spinosus Bufo calamita Bufo canorus Bufo cognatus Bufo danatensis Bufo dhufarensis Bufo exsul ... Bufo galeatus Bufo gargarizans bufogenin Bufo granulosus Bufo japonica Bufo japonicus Bufo japonicus formosus bufokinin Bufo ...
May | 2013 | Naturally Curious with Mary Holland
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... bufo Bufo Bufo alvarius Bufo americanus Bufo andersonii Bufo arenarum Bufo boreas Bufo boreas halophilus Bufo bufo Bufo bufo ... acrylaldehydes acrylamide acrylamides acrylamido acrylamidoethyl acrylamidoethyl glycoside acrylamidoethyl glycosides acrylate ... Bufo bufo japonicus Bufo bufo spinosus Bufo calamita Bufo canorus Bufo cognatus Bufo danatensis Bufo dhufarensis Bufo exsul ... Bufo galeatus Bufo gargarizans bufogenin Bufo granulosus Bufo japonica Bufo japonicus Bufo japonicus formosus bufokinin Bufo ...
DAMNATORY
EDNA DILL CPAR BUDD BUBO COIF DING BUBS COHO CPFA COIL FEE ANASTOMOSES FADO BUFF SPECTRUM COIR BUDS DINT COMA COMB COLI BUFO ... INTERRUPTION COLLEGIAL WISENT SACCHARATE VOMITS FORWARDEST EXTOLED MAGICIAN COCAINIZE VOIDED BUSTLE YS WISHED GLYCOSIDE HISPANO ... DEPUTED ADOWN AGATE WHIMSICALITIES AGARS ADOZE AGAVE BREECHCLOTH HAULER ABSTAINING ROUNDEL EXPEDIENCIES ANGLOPHOBES GLYCOSIDES ...
Berries2
- Exposure to plants containing glycosides can occur through ingestion of sap, berries, leaves, blossoms, or seeds, or of teas brewed from plant parts. (medscape.com)
- Except for the flowers and ripe berries (but including the ripe seeds), all parts of the plant are poisonous to mammals, containing the cyanogenic glycoside sambunigrin (C14H17NO6, CAS number 99-19-4). (wikipedia.org)
Seeds2
- Toxicity may occur after consuming teas brewed from plant parts or after consuming leaves, flowers, or seeds from plants containing cardiac glycosides. (medscape.com)
- The seeds and all green parts of the plant contain cyanogenic glycosides. (wikipedia.org)
Toxic2
- The following cultivars have gained the Royal Horticultural Society's Award of Garden Merit: S. nigra f. laciniata (cut-leaved alder) S. nigra f. porphyrophylla 'Eva' S. nigra f. porphyrophylla 'Gerda' Components of the elderberry plant, including its fruit, contain diverse phytochemicals, such as alkaloids, lectins, and cyanogenic glycosides, which may be toxic if consumed raw. (wikipedia.org)
- Bufonis Venenum,the dried secretion of Bufo bufo gargarizans or B. melanostictus,is toxic and hard with the efficacy of removing toxicity for detumescence and relieving pain. (bvsalud.org)
Ouabain2
- It is present in the skin of the cane toad (Bufo marinus) at a concentration equivalent to ouabain of ~1 mM. (edu.au)
- The in vitro growth inhibitory effects of seven cardiac glycosides including five cardenolides (ouabain, digoxin, digitoxin, gitoxin, uzarigenin-rhamnoside, and their respective aglycone forms) and two bufadienolides (gamabufotalin-rhamnoside and hellebrin, and their respective aglycone forms) were determined by means of the MTT colorimetric assay and hellebrigenin-induced cytotoxic effects were visualized by means of quantitative videomicroscopy. (biomedcentral.com)
Cardiac glycosides11
- Ancient Egyptians and Romans first used plants containing cardiac glycosides medicinally as emetics and for heart ailments. (medscape.com)
- Toxicity from herbal cardiac glycosides was well recognized by 1785, when William Withering published his classic work describing therapeutic uses and toxicity of foxglove, D purpurea. (medscape.com)
- Therapeutic use of herbal cardiac glycosides continues to be a source of toxicity today. (medscape.com)
- Cardiac glycosides have been also found in Asian herbal products and have been a source of human toxicity. (medscape.com)
- Toxicity may occur after consuming teas brewed from plant parts or after consuming leaves, flowers, or seeds from plants containing cardiac glycosides. (medscape.com)
- More than 200 naturally occurring cardiac glycosides have been identified. (medscape.com)
- Cardiac glycosides also have vagotonic effects, resulting in bradycardia and heart block. (medscape.com)
- Cardiac glycosides primarily affect cardiovascular, neurologic, and gastrointestinal systems. (medscape.com)
- At therapeutic doses, cardiac glycosides also may increase inotropy. (medscape.com)
- They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. (labome.org)
- Milkweeds in the genus Asclepias are a classic chemically defended clade of plants with toxic cardenolides (cardiac glycosides) and pressurized latex employed as anti-herbivore weapons. (labome.org)
Marinus1
- In addition, the venom gland of cane toad (Bufo marinus) contains large quantities of a purported aphrodisiac substance that has resulted in cardiac glycoside poisoning. (medscape.com)
Plants2
- Exposure to plants containing glycosides can occur through ingestion of sap, berries, leaves, blossoms, or seeds, or of teas brewed from plant parts. (medscape.com)
- Previously, only several spirostanol glycosides with 25S configuration were isolated from Paris plants. (bvsalud.org)
Skin2
- The venom glands are usually on the skin of the back and contain cardiotoxic glycosides, cholinolytics, and a number of other bioactive materials, many of which have been characterized. (lookformedical.com)
- The dried secretion from the auricular and skin glands of Chinese toad ( Bufo bufo gargarizans ) is named Chansu, which has been used in Traditional Chinese Medicine (TCM) for treating infection and inflammation for hundreds of years Dysecdysis in a juvenile Puerto Rican crested toad (Peltophryne lemur) with an early case of brown skin disease showing dark adherent unshed skin. (chodte-intresserad.com)
Plant1
- Dobler S, Petschenka G, Pankoke H. Coping with toxic plant compounds--the insect's perspective on iridoid glycosides and cardenolides. (labome.org)