The abundant submucosal mucous glands in the DUODENUM. These glands secrete BICARBONATE IONS; GLYCOPROTEINS; and PEPSINOGEN II.

Presence of sorbin in human digestive tract and endocrine digestive tumours. (1/55)

BACKGROUND: Sorbin, a 153 amino acid peptide isolated from porcine intestine, was localised by immunohistochemistry in endocrine cells of the intestinal mucosa and pancreas and in the enteric nervous system in the pig. AIMS: To identify sorbin cells in normal human digestive tissues and to explore the expression of sorbin in 37 digestive endocrine tumours: 14 intestinal carcinoid tumours and 23 endocrine pancreatic tumours including six insulinomas. METHODS: Two polyclonal antibodies against the C-terminal and the N-terminal sequences of porcine sorbin raised in rabbit were used to evaluate sorbin expression by immunohistochemistry. RESULTS: In the human digestive tract, sorbin, characterised by both C-terminal and N-terminal immunoreactivity, was found in enterochromaffin cells of the gastric and intestinal epithelium from the pyloric junction to the descending colon. C-Terminal sorbin immunoreactivity alone was found in plexii from the enteric nervous system and in some insulin-containing cells of normal pancreas. C-Terminal and N-terminal antibodies disclosed sorbin in five of 14 intestinal carcinoid tumours; C-terminal antibody alone disclosed a C-terminal sorbin peptide in two of six insulinomas and three of 17 endocrine pancreatic tumours. The presence of sorbin was not associated with a specific clinical syndrome. CONCLUSIONS: Sorbin is present in the digestive tract in several forms. It is expressed in some intestinal and pancreatic endocrine tumours.  (+info)

A novel in vitro model of Brunner's gland secretion in the guinea pig duodenum. (2/55)

A novel in vitro model that combined functional and morphological techniques was employed to directly examine pathways regulating Brunner's gland secretion in isolation from epithelium. In vitro submucosal preparations were dissected from guinea pig duodenum. A videomicroscopy technique was used to measure changes in luminal diameter of glandular acini as an index of activation of secretion. Carbachol elicited concentration-dependent dilations of the lumen (EC(50) = 2 microM) by activating muscarinic receptors on acinar cells. Ultrastructural and histological analyses demonstrated that dilation was accompanied by single and compound exocytosis of mucin-containing granules and the accumulation of mucoid material within the lumen. Inflammatory mediators (histamine, PGE(1), PGE(2)) and intestinal hormones (CCK, gastrin, vasoactive intestinal polypeptide, secretin) also stimulated glandular secretion, whereas activation of submucosal secretomotor neurons by 5-hydroxytryptamine did not. This study directly demonstrates that multiple hormonal, inflammatory, and neurocrine agents activate Brunner's glands, whereas many have dissimilar effects on the epithelium. This suggests that Brunner's glands are regulated by pathways that act both in parallel to and in isolation from those controlling epithelial secretion.  (+info)

A histochemical study of the camel (Camelus bactrianus) duodenal glands. (3/55)

The complex carbohydrates in the camel duodenal glands were examined histochemically at light and electron microscopic levels. The duodenal glands of the camel were distributed in the submucosa 2 m caudal from the pylorus. These were branched tubuloalveolar glands. The terminal portion of each lobule was formed by only one type of mucous cell. The duodenal gland cells contained acidic and neutral carbohydrates. The mucous cells mainly contained sulfate and carboxyl carbohydrate with sialic acid, and they also contained a few neutral carbohydrates with different saccharide residues such as mannose, glucose, galactose, N-acetyl glucosamine and N-acetyl galactosamine. The results showed that the secretary granules of the duodenal glands in the camel contain mainly acidic carbohydrates. These findings seem to be the morphological characteristics of the duodenal glands in the camel.  (+info)

Dynamic regulation of mucus gel thickness in rat duodenum. (4/55)

We examined the dynamic regulation of mucus gel thickness (MGT) in vivo in rat duodenum in response to luminal acid, cyclooxygenase (COX) inhibition, and exogenous PGE(2). An in vivo microscopic technique was used to measure MGT with fluorescent microspheres in urethan-anesthetized rats. Duodenal mucosa was topically superfused with pH 7.0 or pH 2.2 solutions with or without PGE(2) and indomethacin treatments. Glycoprotein concentration of duodenal loop perfusates was measured with periodic acid/Schiff (PAS) or Alcian blue (AB) staining. MGT and perfusate glycoprotein concentration were stable during a 35-min perfusion with pH 7.0 solution. Acid exposure increased MGT and PAS- and AB-positive perfusate glycoprotein concentrations. Indomethacin pretreatment increased both PAS- and AB-positive perfusate glycoprotein at baseline; subsequent acid superfusion decreased perfusate glycoproteins and gel thickness. PGE(2) (1 mg/kg iv) simultaneously increased MGT and PAS-positive perfusate glycoprotein concentrations followed by a transient increase in AB-positive glycoprotein concentration, suggesting contributions from goblet cells and Brunner's glands. Parallel changes in MGT and perfusate glycoprotein concentration in response to luminal acid and PGE(2) suggest that rapid MGT variations reflect alterations in the balance between mucus secretion and exudation, which in turn are regulated by a COX-related pathway. Luminal acid and PGE(2) augment mucus secretion from goblet cells and Brunner's glands.  (+info)

Neural pathways regulating Brunner's gland secretion in guinea pig duodenum in vitro. (5/55)

This study examined the neural pathways innervating Brunner's glands using a novel in vitro model of acinar secretion from Brunner's glands in submucosal preparations from the guinea pig duodenum. Neural pathways were activated by focal electrical stimulation and excitatory agonists, and videomicroscopy was used to monitor dilation of acinar lumen. Electrical stimulation of perivascular nerves evoked large dilations that were blocked by TTX (1 microM) or the muscarinic receptor antagonist 4-diphenylacetoxy-N-(2-chloroethyl)-piperidine hydrochloride (1 microM). The nicotinic agonist 1,1-dimethyl-4-phenylpiperazinium iodide (100 microM) had no effect, and the nerve-evoked responses were not inhibited by hexamethonium (200 microM). Dilations were abolished in preparations from chronically vagotomized animals. Activation of submucosal ganglia significantly dilated submucosal arterioles but not Brunner's glands. Effects of electrical stimulation of perivascular and submucosal nerves were not altered by guanethidine. Capsaicin and substance P also dilated arterioles but had no effect on Brunner's glands. Cholinergic (choline acetyltransferase-immunoreactive) nerve fibers were found in Brunner's glands. These findings demonstrate that Brunner's glands are innervated by cholinergic vagal fibers but not by capsaicin-sensitive or intrinsic enteric nerves.  (+info)

Endoscopic resection of a large Brunner's gland adenoma. (6/55)

Brunner's gland adenoma is a rare benign tumour of the duodenum. Less than 150 cases have been reported in English literature. We report a 73-year-old woman presenting with upper gastrointestinal obstructive symptoms and melena. Duodenoscopy revealed a large pedunculated tumour in the bulbus duodeni. Endoscopic snare polypectomy was successfully performed. Histological examination revealed a Brunner's gland adenoma. The literature on Brunner's gland adenoma is reviewed.  (+info)

Malignant potential in a Brunner's gland hamartoma. (7/55)

Brunner's gland hamartomas are rare tumours of the duodenum. These lesions have previously been described as being benign, with no malignant potential. A case report is presented of a Brunner's gland hamartoma, whose histology revealed a focus of well marked epithelial dysplasia. This case suggests a dysplastic stage in the natural history of Brunner's gland hamartoma, and questions the malignant potential of these lesions.  (+info)

Potassium currents regulating secretion from Brunner's glands in guinea pig duodenum. (8/55)

This study examined the role of outward K(+) currents in the acinar cells underlying secretion from Brunner's glands in guinea pig duodenum. Intracellular recordings were made from single acinar cells in intact acini in in vitro submucosal preparations, and videomicroscopy was employed in the same preparation to correlate these measures with secretion. Mean resting membrane potential was -74 mV and was depolarized by high external K(+) (20 mM) and the K(+) channel blockers 4-aminopyridine (4-AP), quinine, and clotrimazole. The cholinergic agonist carbachol (60-2,000 nM; EC(50) = 200 nM) caused a concentration-dependent initial hyperpolarization of the membrane and an associated decrease in input resistance. This hyperpolarization was significantly decreased by 20 mM external K(+) or membrane hyperpolarization and increased by 1 mM external K(+) or membrane depolarization. It was blocked by the K(+) channel blockers tetraethylammonium (TEA), 4-AP, quinine, and clotrimazole but not iberiotoxin. When videomicroscopy was employed to measure dilation of acinar lumen in the same preparation, carbachol-evoked dilations were altered in a parallel fashion when external K(+) was altered. The dilations were also blocked by the K(+) channel blockers TEA, 4-AP, quinine, and clotrimazole but not iberiotoxin. These findings suggest that activation of outward K(+) currents is fundamental to the initiation of secretion from these glands, consistent with the model of K(+) efflux from the basolateral membrane providing the driving force for secretion. The pharmacological profile suggests that these K(+) channels belong to the intermediate conductance group.  (+info)

Brunner glands, also known as submucosal glands of Brunner, are tubulo-acinar exocrine glands located in the submucosa of the duodenum, which is the first part of the small intestine. These glands secrete alkaline mucus that helps neutralize the acidic chyme (partially digested food) entering from the stomach, providing a more favorable environment for the enzymes involved in nutrient absorption and protecting the duodenal mucosa from acid-induced damage.

... (or duodenal glands) are compound tubuloalveolar submucosal glands found in that portion of the duodenum which ... Hyperplasia of Brunner glands with a lesion greater than 1 cm was initially described as a Brunner gland adenoma. Several ... The Brunner glands, which empty into the intestinal glands, secrete an alkaline fluid composed of mucin, which exerts a ... Johann Conrad Brunner. The duodenum can be distinguished from the jejunum and ileum by the presence of Brunner's glands in the ...
Stokes, J. F.; Turnberg, L. A.; Hawksley, J. C. (1964). "Hyperplasia of Brunner's glands". Gut. 5 (5): 459-462. doi:10.1136/gut ...
"Brunner's gland hyperplasia": Hypertrophy of Brunner's glands in the submucosal layer of the duodenum. "Brunner's gland adenoma ... in 1687 he described tubuloalveolar glands in the submucous layer of the duodenum, which were later named Brunner's glands. Two ... Polyp-like tumours arising from Brunner's glands. Poetum monstrosum et bicipitem, Diss. med. Strassburg 1672 De glandulis in ... In 1716, Brunner was appointed personal physician to Charles III Philip the new Elector of the Palatinate. He received many ...
Glands line the duodenum, known as Brunner's glands, which secrete mucus and bicarbonate in order to neutralise stomach acids. ... Brunner's glands, which secrete mucus, are only found in the duodenum. The duodenum wall consists of a very thin layer of cells ... These are distinct glands not found in the ileum or jejunum, the other parts of the small intestine.: 274-275 Dog Duodenum 100X ...
... the submucosal glands of the esophagus. For the intestine there are Brunner's glands, the submucosal glands of the duodenum. ... Submucosal glands can refer to various racemose exocrine glands of the mucous type. These glands secrete mucus to facilitate ... The glands themselves are quite complex. The mucus factory is at the bottom, in the submucosa, it is composed of many little ... The submucosal glands are a companion to goblet cells which also produce mucus, and are found lining the same tubes. In the ...
The Brunner's glands secrete large amounts of alkaline mucus in response to (1) tactile or irritating stimuli on the duodenal ... In histology, an intestinal gland (also crypt of Lieberkühn and intestinal crypt) is a gland found in between villi in the ... which increases Brunner's glands secretion concurrently with increase in stomach secretion; and (3) gastrointestinal hormones, ... and at the base of the gland, Paneth cells (secreting anti-microbial peptides) and stem cells. Intestinal glands are found in ...
The duodenum contains Brunner's glands, which produce a mucus-rich alkaline secretion containing bicarbonate. These secretions ...
The duodenum contains Brunner's glands which produce a mucus-rich alkaline secretion containing bicarbonate. These secretions, ... salivary glands, pancreas, liver and gallbladder). The tract may also be divided into foregut, midgut, and hindgut, reflecting ...
Brunner's glands are found in the duodenum but not in other parts of the small intestine. In the colon, epithelium is simple ... Numerous intestinal glands as pocket-like invaginations are present in the underlying tissue. In the large intestines, villi ... In the stomach, the epithelium is simple columnar, and is organised into gastric pits and glands to deal with secretion. In the ... are absent and a flat surface with thousands of glands is observed. Underlying the epithelium is the lamina propria, which ...
Brunner's glands are not found in the ileum, but are a distinctive feature of the duodenum. Goblet cells in the wall of an ... are only found at the bottom of the intestinal glands and release antimicrobial substances such as alpha defensins and lysozyme ...
The jejunum contains very few Brunner's glands (found in the duodenum) or Peyer's patches (found in the ileum). However, there ...
Duodenal enterocytes, Brunner's glands and entero-endocrine cells (including those in the gastric antrum) are dependent on Pdx1 ...
Examples include Brunner's glands, esophageal glands, and pyloric glands Seromucous glands (mixed) secrete both protein and ... mainly serous gland. Sebaceous glands secrete sebum, a lipid product. These glands are also known as oil glands, e.g. Fordyce ... maximum sweat glands of humans, salivary glands, goblet cells, intestinal glands, tear glands, etc. Apocrine - the apical ... Exocrine glands are glands that secrete substances on to an epithelial surface by way of a duct. Examples of exocrine glands ...
... either simple tubular with short ducts or compound racemose resembling the duodenal Brunner's glands. The fundic glands (or ... There are two types of gland in the stomach, the oxyntic gland, and the pyloric gland. The major type of gastric gland is the ... The pyloric gland secretes gastrin from its G cells. Pyloric glands are similar in structure to the oxyntic glands but are ... The other type of gastric gland is the pyloric gland which is an endocrine gland that secretes the hormone gastrin produced by ...
There is a large glandular sac attached to the duodenum, which is lined by Brunner's glands, and secretes alkaline mucus into ...
... lunar crater Brunner (surname) Brunner the Bounty Hunter, a character from the Warhammer setting Brunner's glands, part of the ... Brunner may refer to: Brunner, New Zealand Lake Brunner, New Zealand Brunner Mine, New Zealand Brunner, Houston, United States ... This disambiguation page lists articles associated with the title Brunner. If an internal link led you here, you may wish to ...
Brunner Glands MeSH A03.556.124.684.249 - ileum MeSH A03.556.124.684.249.400 - ileocecal valve MeSH A03.556.124.684.249.612 - ... minor salivary glands MeSH A03.556.500.760.687 - sublingual gland MeSH A03.556.500.760.812 - submandibular gland MeSH A03.556. ... Brunner Glands MeSH A03.556.875.500 - esophagus MeSH A03.556.875.500.180 - esophageal mucosa MeSH A03.556.875.500.360 - upper ... salivary glands MeSH A03.556.500.760.464 - parotid gland MeSH A03.556.500.760.640 - salivary ducts MeSH A03.556.500.760.650 - ...
The secretion of HCO− 3 (bicarbonate anion) from Brunner's glands of the duodenum serves to neutralize the highly acidified ...
... also increases water and bicarbonate secretion from duodenal Brunner's glands to buffer the incoming protons of the ... It is a peptide hormone produced in the S cells of the duodenum, which are located in the intestinal glands. In humans, the ... In 2007, secretin was discovered to play a role in osmoregulation by acting on the hypothalamus, pituitary gland, and kidney. ...
... from the pancreatic duct and also from secretions of bicarbonate-rich mucus from duodenal glands known as Brunner's glands. The ... The main glands are all exocrine glands, secreting via ducts. All of these glands terminate in the mouth. The largest of these ... There are three pairs of main salivary glands and between 800 and 1,000 minor salivary glands, all of which mainly serve the ... It is both an endocrine gland and an exocrine gland. The endocrine part secretes insulin when the blood sugar becomes high; ...
German neurologist Brunner's glands - Johann Conrad Brunner (1653-1727), Swiss anatomist Buck's fascia - Gurdon Buck (1807-1877 ... Pouch of Douglas, Douglas' line - James Douglas (1675-1742), Scottish anatomist Von Ebner's glands - Victor von Ebner (1842- ... Alexander Monro Glands of Montgomery - William Fetherstone Montgomery Hydatids of Morgagni, and Lacunae of Morgagni - Giovanni ... Italian microanatomist Cowper's glands - William Cowper (1666-1709), English surgeon-anatomist Cuvier ducts - Georges Cuvier ( ...
... bronchus Broner Brunner's gland buccal fatpad buccal membrane buccal nerve buccinator bulbospongiosus bulbourethral gland ... pilar cell pillar of fauces pilomotor pilus pineal body pineal gland pinna piriformis piriform sinus pisiform pituitary gland ... fossa sublingual region sublingual salivary gland subluxation submandibular duct submandibular ganglion submandibular gland ... axis axon axon collateral axon hillock azygos Babinski sign baculum ball and socket joint band of Baillarger Bartholin's gland ...
There are two kinds - either simple tubular with short ducts or compound racemose resembling the duodenal Brunner's glands.[ ... an anterior portion lined by fundic glands and a posterior portion lined with pyloric glands. Cardiac glands are unique to ... The glands contains a number of cells, with the function of the glands changing depending on their position within the stomach ... citation needed] Within the body and fundus of the stomach lie the fundic glands. In general, these glands are lined by column- ...
The gland only produces the chemical defence in adult cockroaches. Research has shown that predators including weka, pūkeko and ... "Maoriblatta novaeseelandiae (Brunner von Wattenwyl, 1865)". Catalogue of Life: 2019 Annual Checklist. Retrieved 1 July 2021. ... This species of cockroach has a defensive behaviour of releasing an opaque yellow-coloured liquid from a scent gland that is ...
doi:10.1016/0300-9629(95)02017-9. D. D. Spadacci-Morena; C. Jared; M. M. Antoniazzi; O. Brunner; P. Morena; A. Brunner Jr (1998 ... Epidermal glands are located in the cloacal region of A. alba and are most likely used for reproduction and marking territory. ... The openings of the glands are plugged with a solid, holocrine secretion that is removed when it moves through tunnels and ... C. Jared; M. M. Antoniazzi; I. S. Sano-Martins; A. Brunner Jr. (1995). "Ultrastructural cytology of maturing erythroid cells in ...
Smeltzer, Suzanne C. O'Connell; Bare, Brenda G.; Hinkle, Janice L.; Cheever, Kerry H. (2010). Brunner & Suddarth's Textbook of ... Lavini, Corrado; Moran, Cesar A.; Uliano, Morandi; Schoenhuber, Rudolf (2009). Thymus Gland Pathology: Clinical, Diagnostic and ... Lavini, Corrado; Moran, Cesar A.; Uliano, Morandi; Schoenhuber, Rudolf (2009-05-08). Thymus Gland Pathology: Clinical, ...
Eggs are typically deposited in a froth mass-produced by glands in the abdomen. This froth hardens, creating a protective ... An unusual reproductive strategy is adopted by Brunner's stick mantis from the southern United States; no males have ever been ... ISBN 978-1-118-84616-2. Edmunds, Malcolm; Brunner, Dani (1999). "Ethology of Defenses against Predators". In Prete, Fredrick R ...
... cavity proper Glands of mouth Major salivary glands Parotid gland Sublingual gland Submandibular gland Minor salivary glands ... Patricia Bergquist Vincent Bochdalek James Dixon Boyd Philipp Bozzini Geoffrey Bourne John Browne Charaka Johann Conrad Brunner ... Skin glands Sweat gland Sebaceous gland Nail Lunule Breast Nipple Mammary gland Lactiferous duct Lactiferous sinus Areola ... see genital systems Endocrine system Pituitary gland Pineal gland Thyroid gland Suprarenal gland Pancreatic islets - see ...
Brunner-Routledge. p. 261. ISBN 0-87630-988-0 Old Age Due To Bad Diet. Popular Science (May, 1931). p. 64 Stark, James F. (2018 ... He argued that old age resulted from the "degeneration of the ductless (endocrine) glands)". The book went through four ...
Brunner, H G; Hamel, B C J; van Bokhoven, H (2002). "The p63 gene in EEC and other syndromes". Journal of Medical Genetics. 39 ... Most noted are the abnormal development of hair, teeth, glands, and nails. In HWS, the hair is coarse and sparse, eyelashes are ... van Bokhoven, Hans; Brunner, Han G. (2002). "Splitting p63". The American Journal of Human Genetics. 71 (1): 1-13. doi:10.1086/ ... There may be fewer than normal sweat glands and they may produce little sweat, a condition known generally as hypohidrosis. ...
"Brunners gland hyperplasia": Hypertrophy of Brunners glands in the submucosal layer of the duodenum. "Brunners gland adenoma ... in 1687 he described tubuloalveolar glands in the submucous layer of the duodenum, which were later named Brunners glands. Two ... Polyp-like tumours arising from Brunners glands. Poetum monstrosum et bicipitem, Diss. med. Strassburg 1672 De glandulis in ... In 1716, Brunner was appointed personal physician to Charles III Philip the new Elector of the Palatinate. He received many ...
Hyperplasia of Brunner glands: the spectrum of its radiographic manifestations. Gastrointest Radiol. 1991 Spring. 16 (2):104-8 ... Sorleto M, Timmer-Stranghöner A, Wuttig H, Engelhard O, Gartung C. Brunners Gland Adenoma - A Rare Cause of Gastrointestinal ...
... vacuolar and hydropic degeneration of brunners glands epithelial cells as well as subepithelial blood vessels congestion and ... showed vacuolar and hydropic degeneration of the epithelial cells for the duodenal Brunners glands. H & E. ×160. ... of lymphocytic infiltrations and vascular and hydropic degeneration of epithelial cells lining the duodenal Brunners glands. ...
Brunners glands. Mucus-secreting glands in the duodenum. Glands in the duodenum and jejunum [Described 1687. After Johann ... Konrad Brunner (1653-1727), Swiss anatomist at Heidelberg, then at Strasbourg.] Compound glands of the small intestine, found ...
Features are suggestive of Mild Brunners gland hyperplasia.. No evidence of organisms, increased IELs, atypia or malignancy. ... There is mild submucosal brunners gland hyperplasia. No evidence of parasites, dysplasia or malignancy.. IMPRESSION:. (Method ...
Brunner glands could also be present 2059, serotonin and substance P, are arranged these tumours generally measure only 2 790 [ ...
Secretory cells in Brunners duodenal gland of the mouse have an extensive Golgi complex, with secretory granu... ... Electron micrograph of Maize mosaic virus (MMV, Rhabdoviridae) in secretory cells from the principal salivary gland of the ... Type-d cell from acinus type III of the salivary gland of the tick Rhipicephalus appendiculatus. The... ... Type-e cell from acinus type III of the salivary gland of the tick Rhipiceph... ...
Brunners gland hamartoma presenting as a large duodenal polyp. Shemesh, E., Ben Horin, S., Barshack, I. & Bar-Meir, S., 2000, ...
Brunners Glands. Brunner Glands. Meckels Diverticulum. Meckel Diverticulum. Oddis Sphincter. Sphincter of Oddi. ...
Brunners Glands. Brunner Glands. Meckels Diverticulum. Meckel Diverticulum. Oddis Sphincter. Sphincter of Oddi. ...
Brunners Glands. Brunner Glands. Meckels Diverticulum. Meckel Diverticulum. Oddis Sphincter. Sphincter of Oddi. ...
Brunners glands Brunner, Adolf Brunner, Alois° Brunner, Arnold Brunner, Constantin Brunner, Emil (1899-1966) ...
... with Brunners glands), jejunum, and ileum (with Peyers patches). ... Brunners Glands. - only region of the gastrointestinal tract (along with the esophagus) with glands in the submucosa. ... Digestion requires a neutral pH that is achieved by secretions from Brunners glands and the exocrine pancreas. ...
Appear histologically abnormal and produce excessive secretions (tracheobronchial and Brunner glands). *. Appear histologically ... Nearly all exocrine glands are affected in varying distribution and degree of severity. Glands may ... The FEV1 Respiratory assessment Cystic fibrosis is an inherited disease of the exocrine glands affecting primarily the ... Cystic fibrosis is an inherited disease of the exocrine glands affecting primarily the gastrointestinal and respiratory systems ...
Brunner glands ~2%. *gastric and duodenal ~2%. Development. It is considered a remnant of the omphalomesenteric-vitelline duct ...
Brunners Gland releases a final intestinal secretion. A mucous secretion protects the intestinal lining from the acid chyme. ...
Research Project: Machine Learning Detection of Abnormal Brunners Glands in Duodenal Gastrinoma ...
Brunners glands are present in the submucosa of stomach and secrete pepsinogen ...
Histological analysis showed hyperplasia of Brunners glands correspondent to a Brunners gland hamartoma. BGH was undiagnosed ... Brunners gland hamartoma (BGH) is an infrequently encountered, benign, polypoid proliferation of Brunners glands. Usually ... Brunners gland hamartoma: Case report on a rare duodenal lesion and exhaustive literature review. ... Gastritis cystica profunda (GCP) has been defined as a rare submucosal benign gastric lesion with cystic gland growth. Due to ...
Article: Are giant Brunners gland hyperplasia and gastric heterotopia unknown complications of... ... Article: Gel immersion endoscopic mucosal resection for pedunculated Brunners gland hyperplasia in... ...
The duodenal mucosa is characterized by the presence of Brunners glands, which secrete mucus. ...
The duodenal mucosa is characterized by the presence of Brunners glands, which secrete mucus. ...
Brunners glands. *Burping. C. *Canaliculus (parietal cell). *Cardia. *Catastalsis. *Cecum. *Cephalic phase ...
It is secreted by gastric antral and pyloric glands and by Brunners glands of the duodenum. TFF2 is found in high ...
Brunner gland. *duodenojejunal flexure. *jejunum. * ileum *Meckel diverticulum. *ileocecal valve. *jejunum vs ileum ...
"Johann Conrad Brunner of Diessenhofen, Switzerland, discovered Brunners glands in the duodenum of dogs and man in 1672, ... The duodenal glands had been previously described by Brunners father-in-law, Johann Jacob Wepfer, in 1679, but it was ... BRUNN VON HAMMERSTEIN [BRUNNER], Johann Conrad (1653-1727), preses, FRANK, Georg Friederich, resp.. Exercitatio anatomico- ... Johann Conrad Brunner and His Experiments on the Pancreas in Annals of Medical History, 3rd Ser. vol III, (1941), pp 91-100. ...
Brunners glands) and mixed echo (venous hemangioma) respectively.Conclusions GI-NETs,which possess certain characteristics ... and 5 cases of hyperplasia of Brunners glands, colorectal hyperplastic polyps, colorectal venous hemangioma, colorectal ...
... from the pancreatic duct and also from secretions of bicarbonate-rich mucus from duodenal glands known as Brunners glands. ...
Brunner Glands * Doppler effect * Cross-certification * Candidiasis * Algae * Lysosome * Carcinogenesis * Horsepower * ...
  • Brunner's glands (or duodenal glands) are compound tubuloalveolar submucosal glands found in that portion of the duodenum which is above the hepatopancreatic sphincter (i.e sphincter of Oddi). (wikipedia.org)
  • They are the distinguishing feature of the duodenum, and are named for the Swiss physician who first described them, Johann Conrad Brunner. (wikipedia.org)
  • The duodenum can be distinguished from the jejunum and ileum by the presence of Brunner's glands in the submucosa. (wikipedia.org)
  • Furthermore, in response to the presence of acid in the duodenum, these glands secrete pepsinogen and urogastrone, which inhibit gastric acid secretion. (wikipedia.org)
  • D) In the duodenum, inflammatory cell infiltrates (*) in the submucosa of the duodenum are present between and around Brunner's glands (BG). (cdc.gov)
  • The duodenum showed sub-epithelial congested blood vessels, numerous areas of lymphocytic infiltrations and vascular and hydropic degeneration of epithelial cells lining the duodenal Brunner's glands. (scirp.org)
  • Mucus-secreting glands in the duodenum. (healthbenefitstimes.com)
  • Glands in the duodenum and jejunum [Described 1687. (healthbenefitstimes.com)
  • Compound glands of the small intestine, found in the duodenum and the upper part of the jejunum. (healthbenefitstimes.com)
  • Both Brunner's glands, and the goblet cells in the duodenum secrete mucus. (leeds.ac.uk)
  • CONCLUSIONS: This a rare case of an adenocarcinoma arising from Brunner's gland of the duodenum that was resected by duodenectomy. (bvsalud.org)
  • It is secreted by gastric antral and pyloric glands and by Brunner's glands of the duodenum. (ncl.ac.uk)
  • Johann Conrad Brunner of Diessenhofen, Switzerland, discovered Brunner's glands in the duodenum of dogs and man in 1672, publishing his results in 1687. (ki.se)
  • It also contains submucosa which creates special glands. (wikipedia.org)
  • only region of the gastrointestinal tract (along with the esophagus) with glands in the submucosa. (histologyguide.com)
  • Digestion requires a neutral pH that is achieved by secretions from Brunner's glands and the exocrine pancreas. (histologyguide.com)
  • Major, Ralph 'Johann Conrad Brunner and His Experiments on the Pancreas' in Annals of Medical History, 3rd Ser. (ki.se)
  • c] Whartson's duct is associated with sub-maxillary salivary gland. (studyadda.com)
  • Electron micrograph of Maize mosaic virus (MMV, Rhabdoviridae) in secretory cells from the principal salivary gland of the insect vector Peregrinus maidis (planthopper, Hemiptera, Delphacidae). (cellimagelibrary.org)
  • Figure 381 from Chapter 15 (Cytoplasmic Inclusions) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Type-d cell from acinus type III of the salivary gland of the tick Rhipicephalus appendiculatus. (cellimagelibrary.org)
  • Figures 382 (upper) and 383 (lower) from Chapter 15 (Cytoplasmic Inclusions) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Type-e cell from acinus type III of the salivary gland of the tick Rhipiceph. (cellimagelibrary.org)
  • Although tick salivary gland components have been shown to potentiate virus infection in vertebrate non-reservoirs (i.e. incidental hosts or small animal models of disease), there is a lack of information on the effect of tick salivary gland components on viral infection and shedding in vertebrate reservoirs. (cdc.gov)
  • METHODS: To determine the impact of tick salivary gland components on KASV infection and shedding in ERBs, KASV loads were quantified in blood, oral swab, rectal swab, and urine specimens collected daily through 18days post inoculation from groups of ERBs intradermally inoculated with KASV or KASV+O. (R.) faini tick salivary gland extract (SGE). (cdc.gov)
  • CONCLUSIONS: We report for the first time to our knowledge that tick salivary gland components dampen arbovirus infection and shedding in a vertebrate reservoir. (cdc.gov)
  • After Johann Konrad Brunner (1653-1727), Swiss anatomist at Heidelberg, then at Strasbourg. (healthbenefitstimes.com)
  • The duodenal glands had been previously described by Brunner's father-in-law, Johann Jacob Wepfer, in 1679, but it was Brunner's inaugural dissertation at Heidelberg in 1687 that received popular attention, and his name has been attached to the duodenal glands ever since. (ki.se)
  • Cystic fibrosis is an inherited disease of the exocrine glands affecting primarily the gastrointestinal and respiratory systems. (msdmanuals.com)
  • Nearly all exocrine glands are affected in varying distribution and degree of severity. (msdmanuals.com)
  • Sorleto M, Timmer-Stranghöner A, Wuttig H, Engelhard O, Gartung C. Brunner's Gland Adenoma - A Rare Cause of Gastrointestinal Bleeding: Case Report and Systematic Review. (medscape.com)
  • There is mild submucosal brunner's gland hyperplasia. (mayoclinic.org)
  • Features are suggestive of Mild Brunner's gland hyperplasia. (mayoclinic.org)
  • Brunner's Gland releases a final intestinal secretion. (wellness-studio.co.uk)
  • BACKGROUND: Duodenal carcinoma originating in Brunner's gland is rare. (bvsalud.org)
  • Herein, we report a case of duodenal carcinoma arising from Brunner's gland in a 63-year-old man. (bvsalud.org)
  • Pathological examination revealed that the tumor consisted of tissue from Brunner's gland. (bvsalud.org)
  • Additionally, the carcinoma cells were strongly positive for Mucin-6 protein, which is an epithelial marker of Brunner's gland. (bvsalud.org)
  • Figures 379 (upper) and 380 (lower) from Chapter 15 (Cytoplasmic Inclusions) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Freeze substitution preparations of gerbil parotid gland show condensing vac. (cellimagelibrary.org)
  • citation needed] Hyperplasia of Brunner glands with a lesion greater than 1 cm was initially described as a Brunner gland adenoma. (wikipedia.org)
  • The Brunner glands, which empty into the intestinal glands, secrete an alkaline fluid composed of mucin, which exerts a physiologic anti-acid function by coating the duodenal epithelium, therefore protecting it from the acid chyme of the stomach. (wikipedia.org)
  • the small intestine secretes enzymes and has mucous producing glands . (leeds.ac.uk)
  • Increasingly, successful endoscopic resection has been reported and is primarily used for pedunculated Brunner gland hamartomas. (wikipedia.org)
  • The tissues primarily involved are the skin and its appendages (hair follicles, eccrine glands, sebaceous glands, and, nails) and teeth. (medscape.com)
  • Figure 212 from Chapter 6 (Golgi Apparatus) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Secretory cells in Brunner's duodenal gland of the mouse have an extensive Golgi complex, with secretory granu. (cellimagelibrary.org)
  • Brunner's glands , which are found in the sub-mucosa. (leeds.ac.uk)
  • Glands contributing digestive juices include the salivary glands ( salivary gland ), the gastric glands ( gastric gland ) in the stomach lining, the pancreas , and the liver and its adjuncts-the gallbladder and bile ducts. (en-academic.com)
  • Chewing does aid digestion, however, by reducing food to small particles and mixing it with the saliva secreted by the salivary glands. (en-academic.com)
  • It is postulated that Brunner gland hyperplasia and gastric metaplasia may occur secondary to duodenal mucosal injury. (medscape.com)
  • A recent study from Japan looked at the occurrence of dysplasia and invasive carcinoma in Brunner gland hyperplasia. (medscape.com)
  • [ 8 ] The investigators noted dysplastic changes in 2.1% of cases of Brunner gland hyperplasia, with only 0.3% of those being invasive carcinoma. (medscape.com)
  • In this blog post, we will delve into the various aspects of Brunner's gland hyperplasia, from understanding the condition to exploring the treatment options available. (onhealthfit.com)
  • Additionally, we will explore minimally invasive procedures and surgical interventions that could be considered for managing more severe cases of Brunner's gland hyperplasia. (onhealthfit.com)
  • Understanding the symptoms of Brunner's gland hyperplasia is important for early diagnosis and treatment. (onhealthfit.com)
  • Treatment options for Brunner's gland hyperplasia depend on the severity of the condition and the presence of complications. (onhealthfit.com)
  • Diagnosing Brunner's gland hyperplasia can be challenging, as the condition is relatively rare and often presents with vague symptoms. (onhealthfit.com)
  • Because these symptoms are non-specific, it can be difficult to pinpoint Brunner's gland hyperplasia as the cause. (onhealthfit.com)
  • One of the primary diagnostic tools for Brunner's gland hyperplasia is an upper endoscopy. (onhealthfit.com)
  • During an endoscopy, the doctor may be able to visualize the characteristic nodular hyperplastic lesions that are indicative of Brunner's gland hyperplasia . (onhealthfit.com)
  • Biopsy is another crucial step in diagnosing Brunner's gland hyperplasia . (onhealthfit.com)
  • Fortunately, there are conservative treatment options available for individuals with Brunner's gland hyperplasia. (onhealthfit.com)
  • In some cases, lifestyle modifications, such as stress management techniques and regular exercise, can also play a significant role in managing the symptoms of Brunner's gland hyperplasia. (onhealthfit.com)
  • 12. Brunner's gland hyperplasia. (nih.gov)
  • 13. Gastric-type adenocarcinoma of the duodenal second portion histogenetically associated with hyperplasia and gastric-foveolar metaplasia of Brunner's glands. (nih.gov)
  • Although he was most revered for his contributions to pancreatic physiology, he discovered the duodenal submucosal structures known today as Brunner glands. (medscape.com)
  • Few scattered reports of duodenal adenocarcinoma arising from Brunner glands are found in the literature. (medscape.com)
  • 1. Loss of Lrig1 leads to expansion of Brunner glands followed by duodenal adenomas with gastric metaplasia. (nih.gov)
  • 9. [Adenoma of duodenal Brunner glands combined with aberrant pancreas and chronic gastric ulcer]. (nih.gov)
  • On the walls of the large intestine mucosa are the Brunner glands (which secrete mucus) and Lieberkühn (secreting intestinal juice). (biomanantial.com)
  • Cystic fibrosis is an inherited disease of the exocrine glands affecting primarily the gastrointestinal and respiratory systems. (msdmanuals.com)
  • Nearly all exocrine glands are affected in varying distribution and degree of severity. (msdmanuals.com)
  • Brunner gland adenoma, also known as brunneroma, accounts for approximately 5%-10% of these benign lesions and presents most commonly in the fifth or sixth decade of life. (medscape.com)
  • In a study by Kovacevic and colleagues, [ 7 ] 5 out of 7 patients who were diagnosed with Brunner gland adenoma had concurrent H pylori infections. (medscape.com)
  • 10. Brunner Gland Adenoma. (nih.gov)
  • 14. [Adenoma of Brunner's glands]. (nih.gov)
  • 16. KRAS G12D mutation in Brunner gland adenoma. (nih.gov)
  • The mucosa is rich in mucus-secreting glands, which together with saliva ensure adequate lubrication for the purposes of speech and mastication. (en-academic.com)
  • On the inner surface of each cheek, opposite the second upper molar tooth, is a slight elevation that marks the opening of the parotid duct, leading from the parotid salivary gland, which is located in front of the ear. (en-academic.com)
  • From these three cell types, we generated human antral and fundic gastric tissue containing differentiated glands surrounded by layers of smooth muscle containing functional enteric neurons that controlled contractions of the engineered antral tissue. (nih.gov)
  • All of these organs and glands contribute to the physical and chemical breaking down of ingested food and to the eventual elimination of nondigestible wastes. (en-academic.com)
  • In this case series, we examined 2 Brunner gland tumors. (medscape.com)
  • In addition, Brunner glands secrete enterogastrone, a hormone that inhibits gastric acid secretion. (medscape.com)