Brugia pahangi: A species of parasitic nematode found in man and other mammals. It has been reported from Malaya and East Pakistan and may produce symptoms of tropical eosinophilia.Brugia: A filarial worm of Southeast Asia, producing filariasis and elephantiasis in various mammals including man. It was formerly included in the genus WUCHERERIA.Filariasis: Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.Brugia malayi: A species of parasitic nematode causing Malayan filariasis and having a distribution centering roughly on the Malay peninsula. The life cycle of B. malayi is similar to that of WUCHERERIA BANCROFTI, except that in most areas the principal mosquito vectors belong to the genus Mansonia.Filarioidea: A superfamily of nematodes of the suborder SPIRURINA. Its organisms possess a filiform body and a mouth surrounded by papillae.Microfilaria: The prelarval stage of Filarioidea in the blood and other tissues of mammals and birds. They are removed from these hosts by blood-sucking insects in which they metamorphose into mature larvae.Gerbillinae: A subfamily of the Muridae consisting of several genera including Gerbillus, Rhombomys, Tatera, Meriones, and Psammomys.Elephantiasis, Filarial: Parasitic infestation of the human lymphatic system by WUCHERERIA BANCROFTI or BRUGIA MALAYI. It is also called lymphatic filariasis.Trichlorfon: An organochlorophosphate cholinesterase inhibitor that is used as an insecticide for the control of flies and roaches. It is also used in anthelmintic compositions for animals. (From Merck, 11th ed)Antigens, Helminth: Any part or derivative of a helminth that elicits an immune reaction. The most commonly seen helminth antigens are those of the schistosomes.Larva: Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.Particle Size: Relating to the size of solids.Leukemia L1210Dirofilaria immitis: A filarial parasite primarily of dogs but occurring also in foxes, wolves, and humans. The parasite is transmitted by mosquitoes.Dirofilariasis: Infection with nematodes of the genus DIROFILARIA, usually in animals, especially dogs, but occasionally in man.Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)BooksBiological Therapy: Treatment of diseases with biological materials or biological response modifiers, such as the use of GENES; CELLS; TISSUES; organs; SERUM; VACCINES; and humoral agents.Animal Welfare: The protection of animals in laboratories or other specific environments by promoting their health through better nutrition, housing, and care.Legislation, Medical: Laws and regulations, pertaining to the field of medicine, proposed for enactment or enacted by a legislative body.Social Welfare: Organized institutions which provide services to ameliorate conditions of need or social pathology in the community.Government: The complex of political institutions, laws, and customs through which the function of governing is carried out in a specific political unit.Onchocerca: A genus of parasitic nematodes whose organisms live and breed in skin and subcutaneous tissues. Onchocercal microfilariae may also be found in the urine, blood, or sputum.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Simuliidae: Several species of the genus Simulium (family Simuliidae) that act as intermediate hosts (vectors) for the parasitic disease ONCHOCERCIASIS.Mansonelliasis: Infection with nematodes of the genus MANSONELLA. Symptoms include pruritus, headache, and articular swelling.Onchocerca volvulus: A species of parasitic nematodes widely distributed throughout central Africa and also found in northern South America, southern Mexico, and Guatemala. Its intermediate host and vector is the blackfly or buffalo gnat.Onchocerciasis: Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions.Mansonella: A genus of parasitic nematodes whose organisms are distributed in Central and South America. Characteristics include a smooth cuticle and an enlarged anterior end.Dipetalonema: A filarial nematode parasite of mammalian blood with the vector being a tick or small fly.Dipetalonema Infections: Infections with nematodes of the genus DIPETALONEMA.Acanthocheilonema: A common genus of tropical filarial worms parasitic in humans and monkeys.Alouatta: A genus of the subfamily ALOUATTINAE, family ATELIDAE, inhabiting the forests of Central and South America. Howlers travel in groups and define their territories by howling accompanied by vigorously shaking and breaking branches.Circadian Rhythm: The regular recurrence, in cycles of about 24 hours, of biological processes or activities, such as sensitivity to drugs and stimuli, hormone secretion, sleeping, and feeding.Tropical Climate: A climate which is typical of equatorial and tropical regions, i.e., one with continually high temperatures with considerable precipitation, at least during part of the year. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Trees: Woody, usually tall, perennial higher plants (Angiosperms, Gymnosperms, and some Pterophyta) having usually a main stem and numerous branches.Cebidae: A family of New World monkeys in the infraorder PLATYRRHINI, consisting of nine subfamilies: ALOUATTINAE; AOTINAE; Atelinae; Callicebinae; CALLIMICONINAE; CALLITRICHINAE; CEBINAE; Pithecinae; and SAIMIRINAE. They inhabit the forests of South and Central America, comprising the largest family of South American monkeys.Focal Epithelial Hyperplasia: Hyperplasia of the mucous membrane of the lips, tongue, and less commonly, the buccal mucosa, floor of the mouth, and palate, presenting soft, painless, round to oval sessile papules about 1 to 4 mm in diameter. The condition usually occurs in children and young adults and has familial predilection, lasting for several months, sometimes years, before running its course. A viral etiology is suspected, the isolated organism being usually the human papillomavirus. (Jablonski, Illustrated Dictionary of Dentistry; Belshe, Textbook of Human Virology, 2d ed, p954)Platyrrhini: An infraorder of New World monkeys, comprised of the families AOTIDAE; ATELIDAE; CEBIDAE; and PITHECIIDAE. They are found exclusively in the Americas.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.MEDLINE: The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).Serial Publications: Publications in any medium issued in successive parts bearing numerical or chronological designations and intended to be continued indefinitely. (ALA Glossary of Library and Information Science, 1983, p203)Biological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Quinestrol: The 3-cyclopentyl ether of ETHINYL ESTRADIOL. After gastrointestinal absorption, it is stored in ADIPOSE TISSUE, slowly released, and metabolized principally to the parent compound. It has been used in ESTROGEN REPLACEMENT THERAPY. (From AMA Drug Evaluations Annual, 1992, p1011)Karyometry: Microscopic study of the spacial distribution pattern of CHROMATIN in CELL NUCLEI and CELL NUCLEOLI.Strongyloides stercoralis: A species of parasitic nematode widely distributed in tropical and subtropical countries. The females and their larvae inhabit the mucosa of the intestinal tract, where they cause ulceration and diarrhea.ArchivesStrongyloidiasis: Infection with nematodes of the genus STRONGYLOIDES. The presence of larvae may produce pneumonitis and the presence of adult worms in the intestine could lead to moderate to severe diarrhea.Oligonucleotide Array Sequence Analysis: Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.

Granulomatous inflammatory response to recombinant filarial proteins of Brugia species. (1/45)

The lymphatic inflammatory response in Brugia-infected jirds peaks early during primary infections and then decreases in severity as judged by the numbers of lymph thrombi present within these vessels. Antigen-specific hypersensitivity reactions in these animals was measured by a pulmonary granulomatous inflammatory response (PGRN) induced by somatic adult worm antigen (SAWA)-coated beads, and by cellular proliferative responses of renal lymph node cells. The kinetics of these responses temporally correspond to lymphatic lesion formation. The importance of any single antigen to the induction of this inflammatory response has not been elucidated. In this study, the PGRN was used to measure the cellular immune response to four recombinant filarial proteins during the course of a primary B. pahangi infection. These proteins were BpL4, glycoprotein (glutathione peroxidase) gp29, heat shock protein (hsp) 70, and filarial chitinase. All were fusion proteins of maltose-binding protein (MBP). Control beads included those coated with diethanolamine (DEA), SAWA, or MBP. The measurements of PRGN were made at 14, 28, 56, and > 150 days postinfection (PI) in infected jirds, in jirds sensitized with SAWA, and in uninfected jirds. The secretory homolog of glutathione peroxidase gp29 was the only recombinant protein tested that induced a significantly greater PGRN (P < 0.05) than controls. This was seen at 28 days PI. These observations indicate that gp29 may be part of the worm antigen complex that induces an early inflammatory response, a response similar to that observed with SAWA. These studies indicate that this approach is useful in investigating the functional ability of specific proteins in the induction and down-regulation of immune-mediated inflammatory responses elicited by filarial parasites. Absence of a granulomatous response to the other recombinant proteins used may be related to the nature and sensitivity of the assay used or the character of recombinant proteins tested.  (+info)

Interleukin-10 and antigen-presenting cells actively suppress Th1 cells in BALB/c mice infected with the filarial parasite Brugia pahangi. (2/45)

Infection with the third-stage larvae (L3) of the filarial nematode Brugia results in a Th2-biased immune response in mice and humans. Previously we have shown that the production of interleukin 4 (IL-4) is critical for down-regulating polyclonal Th1 responses in L3-infected mice. However, the in vitro neutralization of IL-4 did not fully recover the defective polyclonal Th1 responses, nor did it result in the production of any antigen (Ag)-specific Th1 cytokines, suggesting that perhaps infection with L3 does not result in priming of Th1 cells in vivo. In this study, we analyzed the role of IL-10 and Ag-presenting cells (APCs) in the spleen as additional factors controlling the Th2 bias in infected mice. Our data show that IL-10 and APCs also contribute to the suppression of mitogen-driven Th1 responses of spleen cells from infected mice. In addition, the neutralization of IL-10 or the replacement of the resident APC population from spleen cell cultures resulted in the production of Ag-specific Th1 cytokines. Irradiated spleen cells from either L3-infected or uninfected mice were able to restore Ag-specific Th1 responses in vitro. Therefore, it appears that Brugia-reactive Th1 cells are primed following infection with L3, but are actively suppressed in vivo by a mechanism that involves IL-10 and the resident APC population, but not IL-4. These results indicate that a complex interplay of cytokines and cell populations underscores the Th2-polarized response in L3-infected mice.  (+info)

Cloning and characterization of two nuclear receptors from the filarial nematode Brugia pahangi. (3/45)

Nuclear receptors (NRs) encompass a superfamily of cytoplasmic/nuclear localized receptors that on ligand binding (or by phosphorylation) directly regulate the transcription of target genes. NRs are involved in many developmental processes, including moulting in insects and dauer larva formation in Caenorhabditis elegans. Here we report the isolation of two genes related to NRs from the filarial nematode Brugia pahangi. Bp-nhr-1 is a member of the NGF1-B subfamily of NRs and is expressed at very low levels in post-infective larval stage 3 (L3) after their transmission to the mammalian host. The second gene, Bp-nhr-2, is related to XR78E/F of Drosophila, a gene involved in the ecdysone response, over the region of its DNA-binding domain. cDNA and genomic clones have been isolated that correspond to Bp-nhr-2. The most striking feature of the encoded protein is that, although there is a DNA-binding domain similar to that of other NRs, the ligand-binding domain is absent. To investigate the pattern of transcription of Bp-nhr-2 in the filarial life cycle, semi-quantitative reverse-transcriptase-mediated PCR was performed; this analysis demonstrated that the gene is expressed in early stages after infection and in the adult and microfilariae, and is up-regulated just before the moult between L3 and L4 but is not expressed during the moult between L4 and adult. Antibodies raised against a peptide corresponding to the transactivation domain of Bp-nhr-2 demonstrate that the protein is expressed in microfilariae and adult samples and that another cross-reactive protein is expressed in these life-cycle stages.  (+info)

B1 B lymphocytes play a critical role in host protection against lymphatic filarial parasites. (4/45)

Host defense against multicellular, extracellular pathogens such as nematode parasites is believed to be mediated largely, if not exclusively, by T lymphocytes. During our investigations into the course of Brugia malayi and Brugia pahangi infections in immunodeficient mouse models, we found that mice lacking B lymphocytes were permissive for Brugian infections, whereas immunocompetent mice were uniformly resistant. Mice bearing the Btk(xid) mutation were as permissive as those lacking all B cells, suggesting that the B1 subset may be responsible for host protection. Reconstitution of immunodeficient recombination activating gene (Rag)-1(-/)- mice with B1 B cells conferred resistance, even in the absence of conventional B2 lymphocytes and most T cells. These results suggest that B1 B cells are necessary to mediate host resistance to Brugian infection. Our data are consistent with a model wherein early resistance to B. malayi is mediated by humoral immune response, with a significant attrition of the incoming infectious larval load. Sterile clearance of the remaining parasite burden appears to require cell-mediated immunity. These data raise the possibility that the identification of molecule(s) recognized by humoral immune mechanisms might help generate prophylactic vaccines.  (+info)

Pharmacokinetics of UMF-078, a candidate antifilarial drug, in infected dogs. (5/45)

The pharmacokinetics of the filaricidal benzimidazole compounds UMF-078 and UMF-289 were evaluated in beagle dogs experimentally infected with Brugia pahangi. Twenty-four infected microfilaremic beagles were selected and randomly allocated into 4 treatment groups of 6 dogs each: oral (PO) UMF-078, PO UMF-289 (the HCl salt form of UMF-078), intramuscular (IM) UMF-078, and untreated controls. Equivalent doses of 50 mg/kg of the free base were given twice a day for 3 days to the 3 groups of treated dogs. Oral absorption is rapid compared with IM dosing; the absorption half-life (K01-HL) for the IM treatment is approximately 14 hr compared with 1 and 2 hr for the PO regimen of salt and free base forms, respectively. The elimination half-lives (K10-HL) for the PO regimens are 13 and 15 hr for the salt and free base forms, respectively. Because of sustained absorption following IM dosing, the K10-HL is prolonged. In contrast to oral administration, IM dosing of UMF-078 provides sustained, relatively low plasma drug levels, with good tolerance and efficacy.  (+info)

Heat shock and developmental expression of hsp83 in the filarial nematode Brugia pahangi. (6/45)

hsp83 was cloned from the filarial nematode Brugia pahangi. The mRNA was constitutively expressed at 37 degrees C in life cycle stages that live in the mammalian host (microfilariae and adult worms). Heat shock resulted in only a minimal increase in levels of transcription. A genomic copy of hsp83 was isolated and was shown to contain 11 introns while sequencing of the 5' upstream region revealed several heat shock elements. Using a chloramphenicol acetyltransferase (CAT) reporter gene construct the expression of hsp83 from B. pahangi (Bp-hsp83) was studied by transfection of COS-7 cells. Similar to the expression pattern in the parasite, CAT activity was detected at 37 degrees C and was not influenced by heat shock. When the free-living nematode Caenorhabditis elegans was transfected with the same construct, CAT activity was not observed at normal growth temperatures (21 degrees C) or under moderate heat shock conditions (28 degrees C). However exposure to more severe heat shock (35 degrees C) resulted in an increase in CAT activity. These results suggest that Bp-hsp83 has a temperature threshold > or = 35 degrees C for expression.  (+info)

NK T cells are a source of early interleukin-4 following infection with third-stage larvae of the filarial nematode Brugia pahangi. (7/45)

Infection of C57BL/6 mice with the third-stage larvae of Brugia pahangi results in a rapid expansion of NK1.1(+) T cells in the spleen and draining lymph nodes. NK T cells produced interleukin-4 in the spleen within 24 h of infection, and these cells were CD4(-).  (+info)

Cloning and expression analysis of two mucin-like genes encoding microfilarial sheath surface proteins of the parasitic nematodes Brugia and Litomosoides. (8/45)

In several filarial genera the first stage larvae (microfilariae) are enclosed by an eggshell-derived sheath that provides a major interface between the parasite and the host immune system. Analysis of the polypeptide constituents of the microfilarial sheath from the cotton rat filaria Litomosoides sigmodontis identified two abundant surface glycoproteins: Shp3a and Shp3. The corresponding genes and the orthologues of the human parasite Brugia malayi and the rodent filaria Brugia pahangi were cloned and sequenced. They encode secreted, mucin-like proteins with N-terminal Ser/Thr-rich repeats and a C-terminal anchor domain rich in aromatic amino acids. About 75% of the protein molecular masses result from post-translational modifications. The Ser/Thr-rich motifs are supposed to serve as targets for dimethylaminoethanol-phosphate substitutions. These modifications were detected only on the sheaths of the late developmental stage of stretched microfilariae, corresponding with the expression of the proteins in the epithelium of the distal part of the uterus and the specific transcription of shp3 and shp3a in the anterior female worm segment. Genomic analysis of all three species demonstrated a conserved linkage of the two genes. Their transcripts undergo cis- and trans-splicing. The transcription start sites of the primary transcripts were determined for the L. sigmodontis genes. The core promoter regions are remarkably conserved between the paralogue genes Ls-shp3a and Ls-shp3 and their orthologues in Brugia, implicating conserved regulatory elements.  (+info)

*Brugia pahangi

... is a parasitic roundworm belonging to the genus Brugia. It is a filarial nematode known to infect the lymph ... Leoaquarius, Sreejith (January 11, 2014). "Brugia pahangi & brugia beaveri". Slideshare. Retrieved 2016-12-26. Kambris, Z; Cook ... Brugia pahangi have been found in cats in Malaysia, Thailand, and Indonesia. A large population of cats, more specifically ... Schacher, John F.. "Morphology of the Microfilaria of Brugia Pahangi and of the Larval Stages in the Mosquito". The Journal of ...

*Armigeres subalbatus

It is a natural vector for filarial worms such as zoonotic Brugia pahangi, and Wuchereria bancrofti, which cause filariasis to ... "Armigeres subalbatus incriminated as a vector of zoonotic Brugia pahangi filariasis in suburban Kuala Lumpur, Peninsular ...

*Brugia

... malayi and Brugia timori cause lymphatic filariasis in humans; and Brugia pahangi and Brugia patei infect domestic cats ... Vincent, Albert L.; Frommes, Stephen P.; Ash, Lawrence R. (1976). "Brugia malayi, Brugia pahangi, and Brugia patei: Pulmonary ... When a new species (now called Brugia pahangi) was discovered in 1956 from dog and cat, J. J. C. Buckley and J. F. B. Edeson ... Buckley, J. J. C. (1960). "On Brugia Gen. Nov. For Wuchereria Spp. of the Malayi Group i.e., W. Malayi (Brug, 1927), W. Pahangi ...

*L-dopachrome isomerase

Trichuris muris and Brugia pahangi". Biochem. J. 335 (3): 495-8. PMC 1219807 . PMID 9794786. Molecular and Cellular Biology ...

*Alae (nematode anatomy)

Brugia pahangi and Brugia malayi, and, as in other nematodes, code for components of the cuticle". Molecular and Biochemical ...

*List of MeSH codes (B01)

... brugia malayi MeSH B01.500.500.294.700.750.700.300.088.550 --- brugia pahangi MeSH B01.500.500.294.700.750.700.300.208 --- ... brugia MeSH B01.500.500.294.700.750.700.300.088.500 --- ...

*Onchocercidae

Brugia Brugia malayi (one cause of filariasis in humans) Brugia pahangi (parasite of domestic cats and wild animals) Brugia ...

*Brugia malayi

After the discovery of new species such as W. pahangi (now B. pahangi) in 1956, and W. patei (now B. patei) in 1958, the ... Plate 2 - Brugia malayi, Brugia timori". World Health Organization. 1997. Cross, John H. (1996), "Filarial Nematodes: Lymphatic ... Brugia Malayi". Fischer, P.; Erickson, S. M.; Fischer, K.; Fuchs, J. F.; Rao, R. U.; Christensen, B. M. & Weil, G. J. (2007), " ... Brugia malayi is a nematode (roundworm), one of the three causative agents of lymphatic filariasis in humans. Lymphatic ...
A role for altered endothelial cell function is emerging in the pathogenesis of disease. We have previously demonstrated that Dirofilaria immitis, the canine heartworm, depresses endothelium-dependent responses and alters the mechanism of relaxation in the in vivo femoral artery of infected dogs. Exposure of rat aorta to the parasite or parasite-conditioned medium selectively depresses endothelium-dependent relaxation. D. immitis is closely related to the major human filarial pathogens. This study was designed to examine the effect of chronic infection with the filarial nematode Brugia pahangi on endothelium-mediated responses of the rat aorta in vitro. We tested the hypothesis that endothelium-dependent responses are depressed in the aorta from rats infected with B. pahangi. Rings of thoracic and abdominal aorta were suspended in muscle baths for measurement of isometric tension. Dose-response relations to norepinephrine, endothelium-dependent dilators (acetylcholine, histamine, and A23187), ...
Abstract A small particle size formulation of 4-isothiocyanato-4′-nitrodiphenylamine has been found to have high chemotherapeutic activity when administered as a single dose to jirds infected with the filarial worm, Brugia pahangi.
The pharmacokinetics of the filaricidal benzimidazole compounds UMF-078 and UMF-289 were evaluated in beagle dogs experimentally infected with Brugia pahangi. Twenty-four infected microfilaremic beagles were selected and randomly allocated into 4 treatment groups of 6 dogs each: oral (PO) UMF-078, PO UMF-289 (the HCl salt form of UMF-078), intramuscular (IM) UMF-078, and untreated controls. Equivalent doses of 50 mg/kg of the free base were given twice a day for 3 days to the 3 groups of treated dogs. Oral absorption is rapid compared with IM dosing; the absorption half-life (K01-HL) for the IM treatment is approximately 14 hr compared with 1 and 2 hr for the PO regimen of salt and free base forms, respectively. The elimination half-lives (K10-HL) for the PO regimens are 13 and 15 hr for the salt and free base forms, respectively. Because of sustained absorption following IM dosing, the K10-HL is prolonged. In contrast to oral administration, IM dosing of UMF-078 provides sustained, relatively low
The survival in culture of adult female Brugia pahangi, Acanthocheilonema viteae, and Onchocerca volvulus and adult male Onchocerca gibsoni was assessed by measuring parasite motility. Survival of all species was maximal in a nutritionally complex me
Using murine peritoneal macrophages and lymphocytes, and human peripheral mononuclear cells (PBMCs), this study shows that saliva of the female Ar. subalbatus induces apoptosis via interaction with the Fas receptor within a few hours but without activating caspase-8. The process further activates downstream p38 MAPK signaling, a cascade that leads to the induction of apoptosis in capase-3 dependent manner. We further illustrate that Ar. subalbatus saliva suppresses proinflammatory cytokines without changing IL-10 levels, which might happen as a result of apoptosis ...
a Plot showing content and sequencing depth. The GC content for B. pahangi is high at the average depth of in between 10 to 180 with GC content value in range o
Cecropin is a cationic antibacterial peptide composed of 35-39 residues. This peptide has been identified as possessing strong antibacterial activity and low toxicity against eukaryotic cells, and it has been claimed that some types of the cecropin family of peptides are capable of killing cancer cells. In this study, the host effect of cloning antibacterial peptide cecropinB2 was investigated. Three different host expression systems were chosen, i.e., Escherichia coli, Bacillus subtilis and Pichia pastoris. Two gene constructs, cecropinB2 (cecB2) and intein-cecropinB2 (INT-cecB2), were applied. Signal peptide and propeptide from Armigeres subalbatus were also attached to the gene construct. The results showed that the best host for cloning cecropinB2 was P. pastoris SMD1168 harboring the gene of pGAPzαC-prepro-cecB2 via Western blot confirmation. The cecropinB2 that was purified using immobilized-metal affinity chromatography resin showed strong antibacterial activity against the Gram-negative strains
Disclaimer: The Animal Diversity Web is an educational resource written largely by and for college students. ADW doesnt cover all species in the world, nor does it include all the latest scientific information about organisms we describe. Though we edit our accounts for accuracy, we cannot guarantee all information in those accounts. While ADW staff and contributors provide references to books and websites that we believe are reputable, we cannot necessarily endorse the contents of references beyond our control. ...
Disclaimer: The Animal Diversity Web is an educational resource written largely by and for college students. ADW doesnt cover all species in the world, nor does it include all the latest scientific information about organisms we describe. Though we edit our accounts for accuracy, we cannot guarantee all information in those accounts. While ADW staff and contributors provide references to books and websites that we believe are reputable, we cannot necessarily endorse the contents of references beyond our control. ...
Brugia is genus for a group of small roundworms. They are among roundworms that cause the parasitic disease filariasis. Specifically, of the three species known, Brugia malayi and Brugia timori cause lymphatic filariasis in humans; and Brugia pahangi and Brugia patei infect domestic cats, dogs and other animals. They are transmitted by the bite of mosquitos. The first species discovered was B. malayi. It was reported by a Dutch parasitologist Steffen Lambert Brug in 1927 from Southeast Asia (Malaya, for which the name was given). It was originally believed to be similar or closely related to another filarial roundworm then named Microfilaria bancrofti (now Wuchereria bancrofti), described by an English naturalist Thomas Spencer Cobbold in 1877. It was for this reason that Brug gave the original name Microfilaria (Filaria) malayi. Brug was aware of the difference mainly on the basis of their occurrence. He found both the worms in Sumatra, Java, Borneo, and Celebes; but in New Guinea only W. ...
During an investigation of arboviruses in China, a novel dsRNA virus was isolated from adult female Armigeres subalbatus. Full genome sequence analysis showed the virus to be related to members of the family Totiviridae, and was therefore named Armigeres subalbatus totivirus (AsTV). Transmission electron microscopy identified icosahedral, non-enveloped virus particles with a mean diameter of 40 nm. The AsTV genome is 7510 bp in length, with two ORFs. ORF1 (4443 nt) encodes the coat-protein and a dsRNA-binding domain (which may be involved in the evasion of gene silencing), while ORF2 (2286 nt) encodes the viral RNA-dependent RNA polymerase (RdRp). The AsTV coat protein shows a higher level of amino acid identity with Drosophila totivirus (DTV, 52 %) than with infectious myonecrosis virus (IMNV, 29 %). Similarly, the RdRp shows higher identity levels with DTV (51 %) than with IMNV (44 %). Identity levels to other members of the family Totiviridae, in either the coat protein or the RdRp, ranged from 6
In the present study, we describe intraperitoneal development of the FR3 strain of Brugia malayi in Mongolian jirds (Meriones unguiculatus). The third molt for male worms occurred between 4 and 7 days
Espesye sa mangungutkut ang Meriones tristrami[2][3][4]. Una ning gihulagway ni Thomas ni adtong 1892. Ang Meriones tristrami sakop sa kahenera nga Meriones sa kabanay nga ilaga.[5][6] Giklaseklase sa IUCN ang espesye sa kinaminosang kalabotan.[1] Pagka karon wala pay siak nga nalista ubos niini niya.[5]. ...
Spencer, L., L. Shultz, and T. V. Rajan. "T Cells Are Required for Host Protection against Brugia malayi but Need Not Produce or Respond to Interleukin-4." Infection and Immunity 71.6 (2003): 3097-3106. Web. 29 Jan. 2020. ...
Definition of Aedes polynesiensis. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
Atrakcje w pobliżu lokalizacji Hotel Acacia (Brugia) w serwisie TripAdvisor: czytaj recenzje najlepszych miejsc wartych odwiedzenia i atrakcji, które trzeba zobaczyć, w pobliżu lokalizacji Hotel Acacia (Brugia, Flandria Zachodnia).
Animal Four Interior Mammalian Mouse Pup Shut Vertebrate: 1 assigned downloads, like Mongolian Jirds or Mongolian Gerbils (Meriones unguiculatus) young, 2 weeks from stock-photos
Abstract: The prostate is not an exclusive male organism, because it is also present in adults females of several rodents species and even in women. The female prostate has been considered homologous to the male ventral prostate, it is composed by sma1l clusters of glands and ducts intermixed to a musculofibrous matrix. It is known nowadays the fundamental importance of the better understanding of the physiological process that maintaÍfi this gland functiona1ly active in the female organism, once that it suffers the same diseases that compromises the male prostate during the climacteric. By this way, the goal of this study was to characterize histologica1ly, cytochemica1ly and ultrasttucturally the tissues components of normal and experimentally treated with testosterone female prostate of gerbil Meriones unguiculatus, during 21 days. In order to do this work, the collected prostates were fixed and embedded for light microscopy and transmission electron microscopy. Cytochemical tests were ...
Breeding Database for Gerbils (Meriones unguiculatus). Horse Data Base is a pedigree database for horse owners. comes from the most prestigious and trusted gaming pedigree online - InterCasino.
Ms Brugia referred to Cedefops long tradition of cooperating with the EESC, stressing that it was, in fact, this Committee that proposed the setting up of a European Centre dealing with vocational education and training (VET).
Rajan, T V.; Greiner, D L.; Yates, J A.; and Shultz, L D., " Growth of the human filarial parasite Brugia malayi in mice lacking major histocompatibility complex class II antigen expression." (1996). Faculty Research 1990 - 1999. 739 ...
This study was designed to investigate the activity of CGP 20376, a benzothiazole derivative, against Brugia malayi in jirds and to illustrate the utility of parasite antigen detection as a means of monitoring drug efficacy in filariasis. Drug treatment was 100% effective in jirds treated 3 or 24 days after infection. Microfilaria and adult worm counts were reduced (relative to counts in sham-treated control animals) by 96% and 95%, respectively, in animals treated 153 days after infection. Four of 6 animals in this treatment group cleared their microfilaremias and were free of adult worms 5 mo after treatment. Thus, CGP 20376 was effective against all life cycle stages of B. malayi in jirds. Parasite antigen levels in jird sera were consistent with parasitological results in all treatment groups, but antigen clearance was incomplete in some cases after apparently successful treatment of mature and immature infections.
Brugia malayi is a filarial nematode, which causes lymphatic filariasis in humans. In 1995, the disease has been identified by the World Health Organization (WHO) as one of the second leading causes of permanent and long-term disability and thus it is targeted for elimination by year 2020. Therefore, accurate filariasis diagnosis is important for management and elimination programs. A recombinant antigen (BmR1) from the Bm17DIII gene product was used for antibody-based filariasis diagnosis in
Aiyar, S.,Zaman, V.,Ha, C.S. (1982). Effect of immune serum on Brugia malayi microfilaria: Ultra structural observations. Southeast Asian Journal of Tropical Medicine and Public Health 13 (1) : 100-104. [email protected] Repository ...
AKL 20303111209 28/04/2011 FOKUS Malaria Pv/Pf Cassette CORE DIAGNOSTICS LTD., UK PT. FOKUS DIAGNOSTIC INDONESIA AKL 20303111329 01/07/2011 RESZON BRUGIA
Pill with imprint 475 is Yellow, Elliptical / Oval and has been identified as Imatinib mesylate 400 mg. It is supplied by Sun Pharma Global FZE.
TY - JOUR. T1 - Inhibitory action of the pineal gland on the nuclear volume of thyroid follicular cells in male gerbils (Meriones unguiculatus). AU - Lewinski, A.. AU - Vaughan, M. K.. AU - Champney, T. H.. AU - Reiter, Russel J. AU - Smith, N. K.. PY - 1984. Y1 - 1984. N2 - Karyometric investigations of thyroid follicular cells were performed in four groups of adult male gerbils [I. sham-operated (Sham PX) + short photoperiod (SPP)-exposed; II. Sham PX + long photoperiod (LPP)-exposed; III. pinealectomized (PX) + SPP-exposed; IV. PX + LPP-exposed]. The mean nuclear volume (MNV) of thyroid cells was significantly higher in both PX groups (III and IV) when compared to Sham PX controls (I and II). In Sham PX gerbils the maintenance of animals in SPP (10 h light : 14 h darkness) for 13 weeks resulted in significant decrease of MNV of thyroid follicular cells in comparison to that in Sham PX animals kept in LPP (14 h light : 10 h darkness). Lighting conditions did not significantly affect the MNV of ...
A gerbil is a small mammal of the order Rodentia. Once known as desert rats, the gerbil subfamily includes about 110 species of African, Indian, and Asian rodents, including sand rats and jirds, all of which are adapted to arid habitats. Most are primarily active during the day, making them diurnal (some species, including the common household pet, exhibit crepuscular behavior), and almost all are omnivorous. One Mongolian species, Meriones unguiculatus, also known as the clawed jird, is a gentle and hardy animal that has become a popular pet. It was first brought from China to Paris in the 19th century, and became a popular house pet. It was then brought to the United States in 1954 by Dr. Victor Schwentker for use in research. The gerbil got its name as a diminutive form of "jerboa", an unrelated group of rodents occupying a similar ecological niche. Gerbils are typically between six and twelve inches (150 and 300 mm) long, including the tail, which makes up about one-half of their total ...
During larval development, filarial nematodes adjust their lifelong reproductive strategy to the presence of anti-parasitic immune cells that determine host resistance and experimental vaccine efficacy.
There are no known conservation measures in place for this species. It may be present in protected areas. Further studies are needed into the abundance, natural history and threats to this species. In China, it has been regionally Red Listed as Least Concern (Wang and Xie 2004 ...
MATERIAL SAFETY DATA SHEET - INFECTIOUS SUBSTANCES SECTION I - INFECTIOUS AGENT NAME: Brugia spp. SYNONYM OR CROSS REFERENCE: Brugia malayi, B. timori, filariasis, Brugian filariasis, Malayan filariasis, Timorean filariasis CHARACTERISTICS: Filarial parasite (nematode), sheathed microfilariae are 200-300 µm in length and 4-7 µm in width SECTION II - HEALTH HAZARD PATHOGENICITY: Characterized by recurring lymphadenitis and lymphangitis accompanied with fever; lymphatic abscesses and consequent scarring are common features; lymphedema appears and progresses to elephantiasis usually confined to the distal extremities in a small proportion of cases EPIDEMIOLOGY: B. malayi endemic in Southeast Asia, rural southwest India, Sri Lanka, China and South Korea: B. timori found in Timor, Flores, Alor, Roti, and South East Indonesia HOST RANGE: Humans, cats, civet, nonhuman primates and mosquitoes INFECTIOUS DOSE: Not known MODE OF TRANSMISSION: By the bite of an infected mosquito; B. malayi transmitted by ...
Wolbachia, a gram negative bacterial endosymbiont belonging to the Rickettiales, has been described in the body of various species of filarial nematodes (Sironi et al. 1995; Bandi et al., 1998, Casiraghi et al., 2001). These bacteria are present in the lateral chords of both males and females, in the reproductive apparatus of females and also in the larvae present in the vector (Bandi et al., 2001). Wolbachia has also been shown to be transovarially transmitted from female worms to the offspring. In addition, a 100% prevalence of infection in the filarial species positive for Wolbachia is suggestive of an obligatory symbiosis between bacteria and its host (Bandi et al., 2001). Furthermore, drugs like tetracycline, known to be effective against Rickettsia-like bacteria, have been shown to cause detrimental effects on filarial nematodes which harbour Wolbachia, and no effects on filarial nematodes which do not harbour these bacteria (Bandi et al., 1999, Hoerauf et al., 1999; Langworthy et al., ...
Testua Creative Commons Aitortu-PartekatuBerdin 3.0 lizentziari jarraituz erabil daiteke; baliteke beste klausularen batzuk ere aplikatu behar izatea. Xehetasunen berri izateko, ikus erabilera-baldintzak ...
By using the combination of reverse-transcription PCR and rapid amplification of cDNA ends methods, a cDNA encoding mast cell tryptase was successfully cloned from the small intestine of Mongolian gerbil, Meriones unguiculatus, infected with Nippostrongylus brasiliensis. The cDNA was 1219 bp long including 810 bp of an open reading frame. Based on the deduced amino acid sequences of known mast cell tryptases of other species, the gerbil mast cell tryptase (gMCT) was highly similar to mouse mast cell protease (mMCP)-7, and seems to be translated as a prepro-enzyme with 25 amino acids of signal and activation peptides and 245 amino acids of mature enzyme. The gMCT mRNA was preferentially transcribed in the intestinal mucosa and to a far lesser extent in the connective tissue such as skin and tongue. Moreover, kinetic study after infection revealed that the amount of gMCT mRNA in the small intestine correlated well with the degree of intestinal mastocytosis. Throughout the course of infection, ...
Lymphatic filariasis (LF), a morbid disease caused by the tissue-invasive nematodes Wuchereria bancrofti, Brugia malayi, and Brugia timori, affects millions of people worldwide. Global eradication efforts have significantly reduced worldwide prevalence, but complete elimination has been hampered by limitations of current anti-filarial drugs and the lack of a vaccine. The goal of this study was to evaluate B. malayi intestinal UDP-glucuronosyltransferase (Bm-UGT) as a potential therapeutic target. To evaluate whether Bm-UGT is essential for adult filarial worms, we inhibited its expression using siRNA. This resulted in a 75% knockdown of Bm-ugt mRNA for 6 days and almost complete suppression of detectable Bm-UGT by immunoblot. Reduction in Bm-UGT expression resulted in decreased worm motility for 6 days, 70% reduction in microfilaria release from adult worms, and significant reduction in adult worm metabolism as detected by MTT assays. Because prior allergic-sensitization to a filarial antigen ...
Host cells respond to viral infections by activating immune response genes that are not only involved in inflammation, but may also predispose cells to cancerous transformation. One such gene is BST-2, a type II transmembrane protein with a unique topology that endows it tethering and signaling potential. Through this ability to tether and signal, BST-2 regulates host response to viral infection either by inhibiting release of nascent viral particles or in some models inhibiting viral dissemination. However, despite its antiviral functions, BST-2 is involved in disease manifestation, a function linked to the ability of BST-2 to promote cell-to-cell interaction. Therefore, modulating BST-2 expression and/or activity has the potential to influence course of disease.
Lymphatic filariasis is a mosquito-borne disease caused by filarioid nematodes. A comparative understanding of parasite biology and host-parasite interactions can provide information necessary for developing intervention programmes for vector control. Here, to understand such interactions, we choose highly susceptible filariasis vectors (Aedes togoi and Anopheles lesteri) as well as Anopheles paraliae, which has lower susceptibility, infected them with nocturnally subperiodic (NSP) Brugia malayi microfilariae (mf) and studied the exsheathment, migration and innate immune responses among them. Mosquito-parasite relationships were systematically investigated from the time mf entered the midgut until they reached their development site in the thoracic musculature (12 time points). Results showed that exsheathment of B. malayi mf occurred in the midgut of all mosquito species and was completed within 24 h post-blood meal. The migration of B. malayi mf from the midgut to thoracic muscles of the highly

Depression of endothelium-dependent relaxation in aorta from rats with Brugia pahangi lymphatic filariasis. | Circulation...Depression of endothelium-dependent relaxation in aorta from rats with Brugia pahangi lymphatic filariasis. | Circulation...

Depression of endothelium-dependent relaxation in aorta from rats with Brugia pahangi lymphatic filariasis.. L Kaiser, P K ... This study was designed to examine the effect of chronic infection with the filarial nematode Brugia pahangi on endothelium- ... Depression of endothelium-dependent relaxation in aorta from rats with Brugia pahangi lymphatic filariasis. ... Depression of endothelium-dependent relaxation in aorta from rats with Brugia pahangi lymphatic filariasis. ...
more infohttp://circres.ahajournals.org/content/68/6/1703

Brugia pahangi - WikipediaBrugia pahangi - Wikipedia

Brugia pahangi is a parasitic roundworm belonging to the genus Brugia. It is a filarial nematode known to infect the lymph ... Leoaquarius, Sreejith (January 11, 2014). "Brugia pahangi & brugia beaveri". Slideshare. Retrieved 2016-12-26. Kambris, Z; Cook ... Brugia pahangi have been found in cats in Malaysia, Thailand, and Indonesia. A large population of cats, more specifically ... Schacher, John F.. "Morphology of the Microfilaria of Brugia Pahangi and of the Larval Stages in the Mosquito". The Journal of ...
more infohttps://en.wikipedia.org/wiki/Brugia_pahangi

Oral Transmission of Brugia Pahangi to Dogs* | The American Journal of Tropical Medicine and HygieneOral Transmission of Brugia Pahangi to Dogs* | The American Journal of Tropical Medicine and Hygiene

Beagle puppies, four anesthetized and two unanesthetized, were exposed to B. pahangi by instilling third-stage larvae (L-3s) ... Abstract Oral transmission of Brugia pahangi, already demonstrated in jirds, has now been accomplished in dogs. ... Oral transmission of Brugia pahangi, already demonstrated in jirds, has now been accomplished in dogs. Beagle puppies, four ... anesthetized and two unanesthetized, were exposed to B. pahangi by instilling third-stage larvae (L-3s) into the mouth. ...
more infohttp://www.ajtmh.org/content/journals/10.4269/ajtmh.1976.25.762

The effect of irradiation on the third stage larvae of Brugia pahangi  - Enlighten: PublicationsThe effect of irradiation on the third stage larvae of Brugia pahangi - Enlighten: Publications

Devaney, E. , Bancroft, A. and Egan, A. (1993) The effect of irradiation on the third stage larvae of Brugia pahangi. Parasite ... The effect of irradiation on the third stage larvae of the filarial nematode Brugia pahangi was investigated. Labelling with ... The effect of irradiation on the third stage larvae of Brugia pahangi ...
more infohttp://eprints.gla.ac.uk/151355/

Chemotactic response of Brugia pahangi infective larvae to jird serum in vitro - Semantic ScholarChemotactic response of Brugia pahangi infective larvae to jird serum in vitro - Semantic Scholar

To our knowledge, this is the first report of a chemotactic response by B. pahangi larvae to host serum. We conclude that B. ... pahangi larvae show a chemotaxic response to host serum, and that cAMP and cAMP dependent protein kinase are involved in the ... The Brugia pahangi infective larval response to jird serum was studied using an agar plate assay. Larvae placed onto the agar ... In vitro chemotactic responses of Brugia pahangi infective larvae to sodium ions.. *Y Mitsui, M Miura, D A Bome, Y Aoki ...
more infohttps://www.semanticscholar.org/paper/Chemotactic-response-of-Brugia-pahangi-infective-to-Gunawardena-Fujimaki/491f202a9d6cd2db55ea8b0ee1bd82b40050e85f

Expression of small heat shock proteins by the third-stage larva of Brugia pahangi  - Enlighten: PublicationsExpression of small heat shock proteins by the third-stage larva of Brugia pahangi - Enlighten: Publications

Jecock, R. M. and Devaney, E. (1992) Expression of small heat shock proteins by the third-stage larva of Brugia pahangi. ... Changes in proteins synthesised by the infective third-stage larvae (L3) of the filarial nematode Brugia pahangi were examined ... Expression of small heat shock proteins by the third-stage larva of Brugia pahangi ...
more infohttp://eprints.gla.ac.uk/151359/

Draft genome of Brugia pahangi: high similarity between B. pahangi and B. malayi | Parasites & Vectors | Full TextDraft genome of Brugia pahangi: high similarity between B. pahangi and B. malayi | Parasites & Vectors | Full Text

Albeit with high similarity to B. malayi genome, the B. pahangi-unique genes found in this study may serve as new focus to ... Subsequently, adult B. pahangi were obtained from the infected gerbil for genomic DNA extraction. Sequencing and subsequently, ... Nevertheless, 166 genes were considered to be unique to B. pahangi, which may be responsible for the distinct properties of B. ... After blood meal on a B. pahangi-harbouring cat, the Aedes togoi mosquitoes were maintained to harvest infective third stage ...
more infohttps://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-015-1064-2

Stage specific gene expression in the post-infective L3 of the filarial nematode, Brugia pahangi<...Stage specific gene expression in the post-infective L3 of the filarial nematode, Brugia pahangi<...

Stage specific gene expression in the post-infective L3 of the filarial nematode, Brugia pahangi. Samuel Allen Moore Martin, S ... Stage specific gene expression in the post-infective L3 of the filarial nematode, Brugia pahangi. / Martin, Samuel Allen Moore ... keywords = "filarial nematode, Brugia pahangi, gene expression, differential screening, cytidine deaminase, spliced leader, ... title = "Stage specific gene expression in the post-infective L3 of the filarial nematode, Brugia pahangi", ...
more infohttps://abdn.pure.elsevier.com/en/publications/stage-specific-gene-expression-in-the-post-infective-l3-of-the-fi

ASTMH - Zaiman Slide LibraryASTMH - Zaiman Slide Library

Brugia pahangi Size: 98 kB. Description: Gross disection of rear canine limb showing dilated lymphatics which have been ...
more infohttps://www.astmh.org/education-resources/zaiman-slide-library?page=213&fileid=3854

SWISS-MODEL Repository | A0A091DTZ9SWISS-MODEL Repository | A0A091DTZ9

Brugia pahangi: A0A0N4TLS2 ; Brugia malayi: A0A4E9FFK1 ; A0A0K0JD75 ; Acanthocheilonema viteae: A0A498SFA0 ; Toxocara canis: ... Brugia timori: A0A0R3Q8V2 ; Camelus ferus: T0MJ22 ; Tropilaelaps mercedesae: A0A1V9X459 ; Seriola dumerili: A0A3B4U786 ; ...
more infohttps://swissmodel.expasy.org/repository/uniprot/A0A091DTZ9

S.I. No. 248/1998 - Safety, Health and Welfare At Work (Biological Agents) (Amendment) Regulations, 1998S.I. No. 248/1998 - Safety, Health and Welfare At Work (Biological Agents) (Amendment) Regulations, 1998

The electronic Irish Statute Book (eISB) comprises the Acts of the Oireachtas (Parliament), Statutory Instruments, Legislation Directory, Constitution and a limited number of pre-1922 Acts.
more infohttp://www.irishstatutebook.ie/eli/1998/si/248/made/en/print

Parasitic Infections | Springer for Research & DevelopmentParasitic Infections | Springer for Research & Development

Brugia malayi:, Brugia pahangi: and Brugia patei:: pulmonary pathology in jirds. Exp Parasitol 1976; 40: 330-354.PubMedCrossRef ... Experimental transmission of Brugia malayi: and Brugia pahangi: to man. Trans R Soc Trop Med Hyg 1960; 54: 229-234.PubMed ... On Brugia buckleyi: sp. n. from the heart and blood vessels of the Ceylon hare. J Helminthol 1961; 35: 209-220.PubMedCrossRef ... Pulmonary nodule caused by a living Brugia malayi-like: filaria in an artery. Am J Trop Med Hyg 1971; 23: 869-876.Google ...
more infohttps://rd.springer.com/chapter/10.1007/978-1-4757-3935-0_15

Onchocercidae - WikipediaOnchocercidae - Wikipedia

Brugia *Brugia malayi (one cause of filariasis in humans). *Brugia pahangi (parasite of domestic cats and wild animals) ...
more infohttps://en.wikipedia.org/wiki/Onchocercidae

Glutamine-supported motility of adult filarial parasites in vitro and the effect of glutamine antimetabolites.Glutamine-supported motility of adult filarial parasites in vitro and the effect of glutamine antimetabolites.

The survival in culture of adult female Brugia pahangi, Acanthocheilonema viteae, and Onchocerca volvulus and adult male ... Brugia pahangi / drug effects*, physiology. Culture Media. Dipetalonema / drug effects*, physiology. Female. Glucose / ... The survival in culture of adult female Brugia pahangi, Acanthocheilonema viteae, and Onchocerca volvulus and adult male ... Motility of B. pahangi incubated in 10 mM succinate was equivalent to that seen with 10 mM glutamine, but no other ...
more infohttp://www.biomedsearch.com/nih/Glutamine-supported-motility-adult-filarial/8459326.html

Do nového oknaDo nového okna

Brugia malayi. 2. Brugia pahangi. 2. Capillaria philippinensis. 2. Capillaria spp.. 2. ...
more infohttp://www.epi.sk/zz/2013-83

CDC - DPDx - Lymphatic FilariasisCDC - DPDx - Lymphatic Filariasis

Zoonotic Brugia pahangi filariasis in a suburbia of Kuala Lumpur City, Malaysia. Parasitology international, 60 (1), pp.111-113 ... Brugia malayi adults in tissue. Brugia spp. have typical features of filarial nematodes in cross-section. Females reach a ... Microfilariae of Brugia malayi. Microfilariae of Brugia malayi are sheathed and in stained blood smears measure 175-230 µm. In ... Microfilaria of Brugia timori are sheathed and measure on average 310 µm in stained blood smears and 340 µm in 2% formalin. ...
more infohttps://www.cdc.gov/dpdx/lymphaticfilariasis/index.html

BioInteractive Search Results | HHMI BioInteractiveBioInteractive Search Results | HHMI BioInteractive

Brugia pahangi. >Endosymbiotic Wolbachia bacteria inhabit the germline tissue of the parasitic nematode, Brugia pahangi. ...
more infohttp://www.hhmi.org/biointeractive/search?sort_by=created&redirect=1

Tetley L[au] - PubMed - NCBITetley L[au] - PubMed - NCBI

cut-1-like genes are present in the filarial nematodes, Brugia pahangi and Brugia malayi, and, as in other nematodes, code for ... Temperature is a cue for gene expression in the post-infective L3 of the parasitic nematode Brugia pahangi. ... The isolation of differentially expressed cDNA clones from the filarial nematode Brugia pahangi. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Tetley+L%5Bau%5D&dispmax=50

Identification and ultrastructural characterization of the Wolbachia symbiont in Litomosoides chagasfilhoi | Parasites &...Identification and ultrastructural characterization of the Wolbachia symbiont in Litomosoides chagasfilhoi | Parasites &...

A comparison of the body wall ultrastructure of Brugia pahangi with that of Brugia malayi. J Parasitol. 1975;63:567-70.View ... Brugia malayi and Brugia timori [6]. Furthermore, parasitism by filarial nematodes can persist for a long time because the ... Wolbachia endosymbiont of Brugia pahangi; AF069068, Endosymbiont of Litomosoides sigmodontis. ... Draft genome of the filarial nematode parasite Brugia malayi. Science. 2007;317:1756-60.View ArticlePubMed CentralPubMedGoogle ...
more infohttps://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-015-0668-x

Lees GM[au] - PubMed - NCBILees GM[au] - PubMed - NCBI

Improvement of in vitro culture conditions of Brugia pahangi four day old developing larvae for use in an antifilarial drug ... Dipetalonema viteae and Brugia pahangi transplant infections in gerbils for use in antifilarial screening. ... A comparison of the response of Dipetalonema viteae and Brugia pahangi adult worms to antifilarial agents in vitro. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Lees+GM%5Bau%5D&dispmax=50
  • Brugia pahangi have been found in cats in Malaysia, Thailand, and Indonesia. (wikipedia.org)
  • however, relaxation in Brugia-infected aorta was significantly greater than control. (ahajournals.org)
  • The mechanism of relaxation in the Brugia-infected abdominal aorta appears to be altered when compared with control, suggesting that parasites are capable of modulating vascular reactivity by inducing changes in endothelial cell behavior. (ahajournals.org)
  • All 9 positive DBS samples showed positive Brugia pahangi and similar nucleotide sequences. (apjtm.org)