A species of parasitic nematode causing Malayan filariasis and having a distribution centering roughly on the Malay peninsula. The life cycle of B. malayi is similar to that of WUCHERERIA BANCROFTI, except that in most areas the principal mosquito vectors belong to the genus Mansonia.
A filarial worm of Southeast Asia, producing filariasis and elephantiasis in various mammals including man. It was formerly included in the genus WUCHERERIA.
A species of parasitic nematode found in man and other mammals. It has been reported from Malaya and East Pakistan and may produce symptoms of tropical eosinophilia.
Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.
The prelarval stage of Filarioidea in the blood and other tissues of mammals and birds. They are removed from these hosts by blood-sucking insects in which they metamorphose into mature larvae.
A superfamily of nematodes of the suborder SPIRURINA. Its organisms possess a filiform body and a mouth surrounded by papillae.
Parasitic infestation of the human lymphatic system by WUCHERERIA BANCROFTI or BRUGIA MALAYI. It is also called lymphatic filariasis.
A subfamily of the Muridae consisting of several genera including Gerbillus, Rhombomys, Tatera, Meriones, and Psammomys.
A genus of bacteria comprised of a heterogenous group of gram-negative small rods and coccoid forms associated with arthropods. (From Bergey's Manual of Systematic Bacteriology, vol 1, 1984)
Any part or derivative of a helminth that elicits an immune reaction. The most commonly seen helminth antigens are those of the schistosomes.
Proteins found in any species of helminth.
Immunoglobulins produced in a response to HELMINTH ANTIGENS.
A filarial parasite primarily of dogs but occurring also in foxes, wolves, and humans. The parasite is transmitted by mosquitoes.
A white threadlike worm which causes elephantiasis, lymphangitis, and chyluria by interfering with the lymphatic circulation. The microfilaria are found in the circulating blood and are carried by mosquitoes.
Deoxyribonucleic acid that makes up the genetic material of helminths.
Pharmacological agents destructive to nematodes in the superfamily Filarioidea.
An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
A filarial nematode parasite of mammalian blood with the vector being a tick or small fly.
Ribonucleic acid in helminths having regulatory and catalytic roles as well as involvement in protein synthesis.
A genus of parasitic nematodes whose organisms live and breed in skin and subcutaneous tissues. Onchocercal microfilariae may also be found in the urine, blood, or sputum.
The genetic complement of a helminth (HELMINTHS) as represented in its DNA.
An enzyme that activates aspartic acid with its specific transfer RNA. EC 6.1.1.12.
A subfamily in the family MURIDAE, comprising the Old World MICE and RATS.
Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.
The functional hereditary units of HELMINTHS.
A class of unsegmented helminths with fundamental bilateral symmetry and secondary triradiate symmetry of the oral and esophageal structures. Many species are parasites.
A family of the order DIPTERA that comprises the mosquitoes. The larval stages are aquatic, and the adults can be recognized by the characteristic WINGS, ANIMAL venation, the scales along the wing veins, and the long proboscis. Many species are of particular medical importance.
The joining of RNA from two different genes. One type of trans-splicing is the "spliced leader" type (primarily found in protozoans such as trypanosomes and in lower invertebrates such as nematodes) which results in the addition of a capped, noncoding, spliced leader sequence to the 5' end of mRNAs. Another type of trans-splicing is the "discontinuous group II introns" type (found in plant/algal chloroplasts and plant mitochondria) which results in the joining of two independently transcribed coding sequences. Both are mechanistically similar to conventional nuclear pre-mRNA cis-splicing. Mammalian cells are also capable of trans-splicing.
The relationship between an invertebrate and another organism (the host), one of which lives at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.
A genus of small free-living nematodes. Two species, CAENORHABDITIS ELEGANS and C. briggsae are much used in studies of genetics, development, aging, muscle chemistry, and neuroanatomy.
A republic stretching from the Indian Ocean east to New Guinea, comprising six main islands: Java, Sumatra, Bali, Kalimantan (the Indonesian portion of the island of Borneo), Sulawesi (formerly known as the Celebes) and Irian Jaya (the western part of New Guinea). Its capital is Djakarta. The ethnic groups living there are largely Chinese, Arab, Eurasian, Indian, and Pakistani; 85% of the peoples are of the Islamic faith.
The small RNAs which provide spliced leader sequences, SL1, SL2, SL3, SL4 and SL5 (short sequences which are joined to the 5' ends of pre-mRNAs by TRANS-SPLICING). They are found primarily in primitive eukaryotes (protozoans and nematodes).
An organochlorophosphate cholinesterase inhibitor that is used as an insecticide for the control of flies and roaches. It is also used in anthelmintic compositions for animals. (From Merck, 11th ed)
The relationship between two different species of organisms that are interdependent; each gains benefits from the other or a relationship between different species where both of the organisms in question benefit from the presence of the other.

Breast filariasis--a case report. (1/64)

An unusual presentation of filariasis as a breast lump simulating breast carcinoma, in a 50 year old woman residing in Pokhara, Nepal. The case was reported on Fine Needle Aspiration Cytology and also evaluated by histopathology. Morphology of the nematode is that of Brugia species which is unusual in Nepal.  (+info)

Pulmonary inflammation induced by a recombinant Brugia malayi gamma-glutamyl transpeptidase homolog: involvement of humoral autoimmune responses. (2/64)

BACKGROUND: A major allergen from the lymphatic filarial parasite Brugia malayi implicated in the pathogenesis of tropical pulmonary eosinophilia (TPE) has recently been cloned and identified as the homolog of the membrane-bound mammalian enzyme gamma-glutamyl transpeptidase (gamma-GT). Patients with acute TPE show autoreactive antibodies against endogenous gamma-GT from the pulmonary epithelium. MATERIALS AND METHODS: Recombinant B. malayi gamma-GT, alone or adsorbed to aluminium hydroxide (AL), was used in a BALB/c mouse model to analyze its antigenic/allergenic potential, its potential to induce pulmonary inflammation, and its capacity to induce autoreacting antibodies. RESULTS: Mice immunized with B. malayi gamma-GT showed significant levels of gamma-GT-specific IgG1, IgG2a, IgG3, IgA, IgE antibodies, and mild blood eosinophilia, even in the absence of adjuvant. Intranasal challenge with B. malayi gamma-GT induced peribronchial and perivascular inflammation characterized by a mixed infiltrate of lymphocytes, neutrophils, eosinophils, and macrophages. Both IL-4 and IFN-gamma were detected in the peripheral blood and in the bronchoalveolar lavage fluid of immunized and intranasally challenged mice. Histological analysis of murine lungs using affinity-purified antibodies from mice immunized with the parasite's gamma-GT revealed the presence of autoimmune antibodies against pulmonary epithelium. Western blot analysis identified the 55 kDa heavy chain subunit of the murine gamma-GT as the target of autoreactive/crossreacting antibodies. CONCLUSION: Our data from the in vivo mouse model demonstrate the potent allergenicity/antigenicity of B. malayi gamma-GT, and its capacity to induce pulmonary inflammation upon intranasal challenge. This leads to breakdown of tolerance against endogenous murine gamma-GT. Thus, humoral autoimmunity against the airways epithelium may contribute to the pathogenesis of TPE.  (+info)

High prevalence of Brugia timori infection in the highland of Alor Island, Indonesia. (3/64)

To identify areas endemic for Brugia timori infection, a field survey was carried out in 2001 on Alor, East Nusa Tenggara Timor, Indonesia. Elephantiasis was reported on this island by villagers as a major health problem. Bancroftian filariasis was detected in four villages in the coastal area, whereas B. timori was identified in four rice-farming villages. No mixed infections with both species were found. In the highland village Mainang (elevation = 880 m), 586 individuals were examined for B. timori infection and 157 (27%) microfilaria carriers were detected. The prevalence of microfilaremic individuals standardized by sex and age was 25%. The geometric mean microfilarial density of microfilaremic individuals was 138 microfilariae/ml. Among teenagers and adults, males tended to have a higher microfilarial prevalence than females. Microfilaria prevalence increased with age and a maximum was observed in the fifth decade of life. In infected individuals, the microfilarial density increased rapidly and high levels were observed in those individuals 11-20 years old. The highest microfilaria density was found in a 27-year-old woman (6,028 microfilariae/ml). Brugia timori on Alor was nocturnally periodic, but in patients with high parasite loads, a small number of microfilariae was also detected in the day blood. The disease rate was high and many persons reported a history of acute filarial attacks. Seventy-seven (13%) individuals showed lymphedema of the leg that occasionally presented severe elephantiasis. No hydrocele or genital lymphedema were observed. This study showed that B. timori infection is not restricted to the lowland and indicated that it might have a wider distribution in the lesser Sunda archipelago than previously assumed.  (+info)

Efficacy and sustainability of a footcare programme in preventing acute attacks of adenolymphangitis in Brugian filariasis. (4/64)

Lymphatic filariasis is associated with considerable disability related to the intensity and frequency of acute adenolymphangitis (ADL) attacks. The global programme for elimination of lymphatic filariasis emphasizes the need to combine transmission control with alleviation of disability. Footcare aimed at the prevention of secondary bacterial infections is the mainstay of disability alleviation programmes. We evaluated the efficacy and sustainability of an unsupervised, personal footcare programme by examining and interviewing 127 patients who had previously participated in a trial that assessed the efficacy of diethylcarbamazine, penicillin and footcare in the prevention of ADL. During the trial period these patients had been educated in footcare and were supervised. During the unsupervised period, which lasted 1 year or longer, 47 patients developed no ADL, and ADL occurred less frequently in 72.5%. Most patients were practising footcare as originally advised, unsupervised and without cost, which proves that such a programme is sustainable and effective.  (+info)

Treatment of Brugia timori and Wuchereria bancrofti infections in Indonesia using DEC or a combination of DEC and albendazole: adverse reactions and short-term effects on microfilariae. (5/64)

Filariasis caused by Brugia timori and Wuchereria bancrofti is an important public health problem on Alor island, East Nusa Tenggara, Indonesia. To implement a control programme, adverse reactions and short-term effects on the microfilaria (mf) density were studied following a divided dose of diethylcarbamazine (DEC, 6 mg/kg body weight - 100 mg on day 1 and the rest on day 3) or a single dose of DEC (6 mg/kg body weight on day 3) and albendazole (Alb, 400 mg). In order to define the most appropriate regimen, 30 persons infected with B. timori were treated in the hospital and results were compared with those obtained from the treatment of 27 persons infected with W. bancrofti. Adverse reactions consisted of systemic reactions such as fever, headache, myalgia, itching and local reactions such as adenolymphangitis. Fever experienced by a number of patients in both treatment groups generally occurred 12-24 h after drug administration and lasted up to 2 days. Adenolymphangitis tended to occur later and was resolved within 4 days. The number of W. bancrofti patients suffering from adverse reactions was lower and the reactions were milder than those of the B. timori patients. There was no difference in adverse reactions between DEC alone and DEC-Alb treatment for either infection. The geometric mean mf count decreased on day 7 in the B. timori infected patients from 234 mf/ml in the DEC group and from 257 mf/ml in the DEC-Alb group to 7 and 8 mf/ml, respectively. The mf densities of the W. bancrofti infected patients decreased on day 7 from 214 mf/ml in the DEC group and from 559 mf/ml in the DEC-Alb group to 15 and 14 mf/ml, respectively. Our data indicate that the microfilaricidal effect of the drugs is achieved more rapidly for B. timori, which is associated with more adverse reactions than W. bancrofti. In addition, 111 B. timori infected persons were treated in the community with DEC-Alb in one selected village. The adverse reactions and the reduction of mf density was similar to the findings of the hospital-based study. In this group, there was a strong correlation of mf density with the frequency and severity of adverse reactions. The addition of Alb resulted in no additional adverse reactions compared with DEC treatment alone and can also be used for the treatment of B. timori infection. In Indonesia, where the prevalence of intestinal helminths is high, the use of a combination of DEC and Alb to control lymphatic filariasis may also have impact on the control of intestinal helminths.  (+info)

Intravascular filarial parasites inhibit platelet aggregation. Role of parasite-derived prostanoids. (6/64)

The nematode parasites that cause human lymphatic filariasis survive for long periods in their vascular habitats despite continual exposure to host cells. Platelets do not adhere to blood-borne microfilariae, and thrombo-occlusive phenomena are not observed in patients with circulating microfilariae. We studied the ability of microfilariae to inhibit human platelet aggregation in vitro. Brugia malayi microfilariae incubated with human platelets caused dose-dependent inhibition of agonist-induced platelet aggregation, thromboxane generation, and serotonin release. As few as one microfilaria per 10(4) platelets completely inhibited aggregation of platelets induced by thrombin, collagen, arachidonic acid, or ionophore A23187. Microfilariae also inhibited aggregation of platelets in platelet-rich plasma stimulated by ADP, compound U46619, or platelet-activating factor. The inhibition required intimate proximity but not direct contact between parasites and platelets, and was mediated by parasite-derived soluble factors of low (less than 1,000 Mr) molecular weight that were labile in aqueous media and caused an elevation of platelet cAMP. Prior treatment of microfilariae with pharmacologic inhibitors of cyclooxygenase decreased both parasite release of prostacyclin and PGE2 and microfilarial inhibition of platelet aggregation. These results indicate that microfilariae inhibit platelet aggregation, via mechanisms that may include the elaboration of anti-aggregatory eicosanoids.  (+info)

Transmission-blocking antibodies recognize microfilarial chitinase in brugian lymphatic filariasis. (7/64)

Brugia malayi is a parasitic nematode that causes lymphatic filariasis in humans. The monoclonal antibody MF1, which mediates clearance of peripheral microfilaremia in a gerbil infection model, recognizes two stage-specific proteins, p70 and p75, in B. malayi microfilariae. cDNA coding for the MF1 antigen was sequenced, and the predicted protein sequence shows significant similarities to chitinases from bacteria and yeast. When microfilarial extracts and purified preparations of the MF1 antigen were tested for chitinase activity, strong bands of chitin-degrading activity comigrated in SDS/PAGE with p70 and p75 and showed a reduction-dependent mobility shift characteristic of the MF1 antigen. Thus, the MF1 antigen is microfilarial chitinase, which may function to degrade chitin-containing structures in the microfilaria or in its mosquito vector during parasite development and transmission.  (+info)

Immunologic tolerance in lymphatic filariasis. Diminished parasite-specific T and B lymphocyte precursor frequency in the microfilaremic state. (8/64)

To explore the mechanisms of antigen-specific immune unresponsiveness seen in microfilaremic patients with bancroftian filariasis, T and B cell precursor frequency analysis was performed using PBMC from individuals with either asymptomatic microfilaremia (MF, n = 7) or chronic lymphatic obstruction (CP, n = 20). Highly purified CD3+ cells were partially reconstituted with adherent cells and their proliferative response to parasite antigens determined in cultures of T cells by limiting dilution analysis. A filter immunoplaque assay also assessed the frequency of both total and parasite-specific Ig-producing B cells. While the lymphocyte proliferation to mitogens and to a nonparasite antigen (Streptolysin-O, [SLO]) were similar in all groups of patients, the frequency of parasite-specific CD3+ T cells was significantly lower (geometric mean [GM], 1/3,757) in MF patients when compared to that in CP patients (GM 1/1,513; P less than 0.001). Similarly, the proportion of lymphocytes producing parasite-specific IgE or IgG was significantly lower in MF patients (IgE mean, 0.2%; IgG mean, 0.33%) compared with CP patients (IgE mean, 3.2%; IgG mean, 1.76%; P less than 0.05 for both comparisons). These observations imply that low numbers of parasite-specific T and B lymphocytes may be partially responsible for the severely diminished capacity of lymphocytes from patients with MF to produce parasite-specific antibody and to proliferate to parasite antigen in vitro. Such differences in parasite-specific lymphocyte responses suggest that tolerance by clonal anergy may be a critical mechanism for maintaining the microfilaremic state.  (+info)

'Brugia malayi' is a species of parasitic nematode (roundworm) that can infect humans and cause the tropical disease known as lymphatic filariasis. The adult worms typically reside in the lymphatic vessels, where they can cause inflammation, obstruction, and damage to the lymphatic system.

The life cycle of 'Brugia malayi' involves several stages, including microfilariae (immature worms) that are transmitted to a human host through the bite of an infected mosquito vector. Once inside the human body, the microfilariae migrate to the lymphatic vessels and mature into adult worms over a period of several months.

The symptoms of lymphatic filariasis can range from mild to severe, depending on the extent of the infection and the individual's immune response. In some cases, the disease can lead to chronic swelling and deformity of the affected limbs or genitalia, a condition known as elephantiasis.

Preventive measures for lymphatic filariasis include avoiding mosquito bites through the use of insect repellent, long-sleeved clothing, and bed nets, as well as mass drug administration programs to eliminate the parasite from affected communities.

'Brugia' is a genus of parasitic nematode worms that are known to cause lymphatic filariasis, a tropical disease affecting the lymphatic system. There are three main species of Brugia that infect humans: Brugia malayi, Brugia timori, and Brugia garinii. These parasites are transmitted to humans through the bite of infected mosquitoes.

Brugia malayi is found primarily in Southeast Asia, while Brugia timori is restricted to the island of Timor in Indonesia. Brugia garinii, on the other hand, is more widely distributed and can be found in parts of Africa and Asia.

The infection caused by these parasites can lead to a range of symptoms, including fever, swelling of the lymph nodes, and elephantiasis, a condition characterized by severe swelling of the limbs or genitals. Preventive measures such as avoiding mosquito bites and mass drug administration programs are in place to control the spread of lymphatic filariasis caused by Brugia species.

'Brugia pahangi' is a species of parasitic nematode (roundworm) that can cause lymphatic filariasis in humans. It is primarily found in Southeast Asia and is transmitted through the bite of infected mosquitoes. The adult worms reside in the lymphatic system, where they can cause inflammation, swelling, and damage to the lymph vessels and nodes. This can lead to a range of symptoms, including fever, chills, headache, and lymphadenopathy (swollen lymph nodes). In advanced cases, it can result in elephantiasis, a severe and disfiguring condition characterized by the thickening and hardening of the skin and underlying tissues.

It's important to note that 'Brugia pahangi' is primarily a veterinary parasite, infecting animals such as cats and dogs, but it can also cause human infections under certain circumstances. Preventive measures include avoiding mosquito bites through the use of insect repellent, wearing long sleeves and pants, and staying indoors during peak mosquito hours. In areas where the parasite is common, public health programs may provide mass drug administration to control the spread of the infection.

Filariasis is a parasitic disease caused by infection with roundworms of the Filarioidea type. The infection is spread through the bite of infected mosquitoes and can lead to various symptoms depending on the type of filarial worm, including lymphatic dysfunction (elephantiasis), eye damage (onchocerciasis or river blindness), and tropical pulmonary eosinophilia. The disease is prevalent in tropical areas with poor sanitation and lack of access to clean water. Preventive measures include wearing protective clothing, using insect repellents, and sleeping under mosquito nets. Treatment typically involves the use of antiparasitic drugs such as diethylcarbamazine or ivermectin.

Microfilaria is the larval form of certain parasitic roundworms (nematodes) belonging to the family Onchocercidae. These worms include species that cause filariasis, which are diseases transmitted through the bite of infected mosquitoes or blackflies. The microfilariae are found in the blood or tissue fluids of the host and can measure from 200 to 300 microns in length. They have a distinct sheath and a characteristic tail taper, which helps in their identification under a microscope. Different filarial species have specific microfilariae characteristics, such as size, shape, and lifestyle patterns (nocturnal or diurnal periodicity). The presence of microfilariae in the host's blood or tissue fluids is indicative of an ongoing infection with the respective filarial parasite.

Filarioidea is a superfamily of parasitic nematode (roundworm) worms, many of which are important pathogens in humans and animals. They are transmitted to their hosts through the bite of insect vectors, such as mosquitoes or flies. The filarioid worms can cause a range of diseases known as filariases. Some examples include Wuchereria bancrofti, Brugia malayi, and Onchocerca volvulus, which cause lymphatic filariasis (elephantiasis) and river blindness, respectively. The adult worms live in the lymphatic system or subcutaneous tissues of their hosts, where they produce microfilariae, the infective stage for the insect vector.

The medical definition of Filarioidea is: A superfamily of parasitic nematode worms that includes several important human pathogens and causes various filariases. The adult worms live in the lymphatic system or subcutaneous tissues, while the microfilariae are taken up by insect vectors during a blood meal and develop into infective larvae inside the vector. These larvae are then transmitted to a new host through the bite of the infected vector.

Elephantiasis, filarial is a medical condition characterized by the severe swelling of limbs or other parts of the body due to the blockage of lymphatic vessels by parasitic worms. It is caused by infection with threadlike nematode filarial worms, such as Wuchereria bancrofti and Brugia timori. These worms are transmitted to humans through mosquito bites.

The blockage of lymphatic vessels leads to the accumulation of lymph fluid in the affected area, causing progressive swelling, thickening, and hardening of the skin and underlying tissues. In advanced cases, the skin may become rough, nodular, and fissured, resembling the hide of an elephant, hence the name "elephantiasis."

The condition is usually chronic and can cause significant disability and social stigma. While there is no cure for filarial elephantiasis, various treatments are available to alleviate symptoms, prevent transmission, and halt the progression of the disease. These include antibiotics to kill the worms, surgery to remove the lymphatic obstruction, and various supportive measures to manage the swelling and prevent secondary infections.

Gerbillinae is a subfamily of rodents that includes gerbils, jirds, and sand rats. These small mammals are primarily found in arid regions of Africa and Asia. They are characterized by their long hind legs, which they use for hopping, and their long, thin tails. Some species have adapted to desert environments by developing specialized kidneys that allow them to survive on minimal water intake.

Wolbachia is a genus of intracellular bacteria that naturally infects a wide variety of arthropods (insects, spiders, mites) and filarial nematodes (roundworms). These bacteria are transmitted vertically from mother to offspring, often through the cytoplasm of eggs. Wolbachia can manipulate the reproductive biology of their hosts in various ways, such as feminization, parthenogenesis, male killing, and cytoplasmic incompatibility, which favor the spread and maintenance of the bacteria within host populations. The interactions between Wolbachia and their hosts have implications for insect pest management, disease transmission, and evolutionary biology.

Helminth antigens refer to the proteins or other molecules found on the surface or within helminth parasites that can stimulate an immune response in a host organism. Helminths are large, multicellular parasitic worms that can infect various tissues and organs in humans and animals, causing diseases such as schistosomiasis, lymphatic filariasis, and soil-transmitted helminthiases.

Helminth antigens can be recognized by the host's immune system as foreign invaders, leading to the activation of various immune cells and the production of antibodies. However, many helminths have evolved mechanisms to evade or suppress the host's immune response, allowing them to establish long-term infections.

Studying helminth antigens is important for understanding the immunology of helminth infections and developing new strategies for diagnosis, treatment, and prevention. Some researchers have also explored the potential therapeutic use of helminth antigens or whole helminths as a way to modulate the immune system and treat autoimmune diseases or allergies. However, more research is needed to determine the safety and efficacy of these approaches.

Helminth proteins refer to the proteins that are produced and expressed by helminths, which are parasitic worms that cause diseases in humans and animals. These proteins can be found on the surface or inside the helminths and play various roles in their biology, such as in development, reproduction, and immune evasion. Some helminth proteins have been identified as potential targets for vaccines or drug development, as blocking their function may help to control or eliminate helminth infections. Examples of helminth proteins that have been studied include the antigen Bm86 from the cattle tick Boophilus microplus, and the tetraspanin protein Sm22.6 from the blood fluke Schistosoma mansoni.

Antibodies are proteins produced by the immune system in response to the presence of a foreign substance, known as an antigen. They are capable of recognizing and binding to specific antigens, neutralizing or marking them for destruction by other immune cells.

Helminths are parasitic worms that can infect humans and animals. They include roundworms, tapeworms, and flukes, among others. Helminth infections can cause a range of symptoms, depending on the type of worm and the location of the infection.

Antibodies to helminths are produced by the immune system in response to an infection with one of these parasitic worms. These antibodies can be detected in the blood and serve as evidence of a current or past infection. They may also play a role in protecting against future infections with the same type of worm.

There are several different classes of antibodies, including IgA, IgD, IgE, IgG, and IgM. Antibodies to helminths are typically of the IgE class, which are associated with allergic reactions and the defense against parasites. IgE antibodies can bind to mast cells and basophils, triggering the release of histamine and other inflammatory mediators that help to protect against the worm.

In addition to IgE, other classes of antibodies may also be produced in response to a helminth infection. For example, IgG antibodies may be produced later in the course of the infection and can provide long-term immunity to reinfection. IgA antibodies may also be produced and can help to prevent the attachment and entry of the worm into the body.

Overall, the production of antibodies to helminths is an important part of the immune response to these parasitic worms. However, in some cases, the presence of these antibodies may also be associated with allergic reactions or other immunological disorders.

"Dirofilaria immitis" is a species of parasitic roundworm that can infect dogs, cats, and other animals, including humans. It is the causative agent of heartworm disease in these animals. The adult worms typically reside in the pulmonary arteries and hearts of infected animals, where they can cause serious damage to the cardiovascular system.

The life cycle of Dirofilaria immitis involves mosquitoes as intermediate hosts. Infected animals produce microfilariae, which are taken up by mosquitoes during blood meals. These larvae then develop into infective stages within the mosquito and can be transmitted to other animals through the mosquito's bite.

In dogs, heartworm disease is often asymptomatic in the early stages but can progress to cause coughing, exercise intolerance, heart failure, and even death if left untreated. In cats, heartworm disease is more difficult to diagnose and often causes respiratory symptoms such as coughing and wheezing.

Preventive measures, such as regular administration of heartworm preventatives, are essential for protecting animals from this parasitic infection.

Wuchereria bancrofti is a parasitic roundworm that causes lymphatic filariasis, also known as elephantiasis. It is transmitted to humans through the bite of infected mosquitoes. The worms infect the lymphatic system and can lead to chronic swelling of body parts such as the limbs, breasts, and genitals, as well as other symptoms including fever, chills, and skin rashes. Wuchereria bancrofti is a significant public health problem in many tropical and subtropical regions around the world.

Helminth DNA refers to the genetic material found in parasitic worms that belong to the phylum Platyhelminthes (flatworms) and Nematoda (roundworms). These parasites can infect various organs and tissues of humans and animals, causing a range of diseases.

Helminths have complex life cycles involving multiple developmental stages and hosts. The study of their DNA has provided valuable insights into their evolutionary history, genetic diversity, and mechanisms of pathogenesis. It has also facilitated the development of molecular diagnostic tools for identifying and monitoring helminth infections.

Understanding the genetic makeup of these parasites is crucial for developing effective control strategies, including drug discovery, vaccine development, and disease management.

Filaricides are a type of medication used to treat infections caused by filarial worms, which are parasitic roundworms that can infect humans and animals. These medications work by killing or inhibiting the development of the larval stages of the worms, thereby helping to eliminate the infection and prevent further transmission.

Filaricides are often used to treat diseases such as onchocerciasis (river blindness), lymphatic filariasis (elephantiasis), and loiasis (African eye worm). Examples of filaricides include ivermectin, diethylcarbamazine, and albendazole. It is important to note that these medications should only be used under the guidance of a healthcare professional, as they can have serious side effects if not used properly.

Diethylcarbamazine (DECT or DEC) is an anti-parasitic medication used to treat infections caused by roundworms, including lymphatic filariasis (elephantiasis) and river blindness (onchocerciasis). It works by killing the parasitic worms, thus helping to prevent the progression of these diseases.

Diethylcarbamazine is typically available as a prescription oral medication in the form of tablets or capsules. The dosage and duration of treatment will depend on the type and severity of the infection being treated. It's important to note that DEC should only be taken under the supervision of a healthcare professional, as it may have side effects and potential drug interactions.

Medical Citation:
"Diethylcarbamazine." National Center for Biotechnology Information. PubChem Compound Database. U.S. National Library of Medicine. . Accessed on April 18, 2023.

Dipetalonema is a genus of parasitic nematodes (roundworms) that can infect various mammals, including humans. Two species within this genus, Dipetalonema perstans and Dipetalonema streptocerca, are known to cause human filariasis, a group of tropical diseases characterized by the presence of parasitic worms in the lymphatic system.

Dipetalonema perstans is also known as "persistent strongyloides" and can cause a condition called "tropical pulmonary eosinophilia." This species has a complex life cycle involving mosquitoes as intermediate hosts. The adult worms reside in the abdominal cavity of the human host, where they produce microfilariae that circulate in the bloodstream. When an infected mosquito takes a blood meal, it ingests the microfilariae, which then develop into infective larvae inside the mosquito. Upon subsequent bites by the mosquito, these infective larvae enter the human host and migrate to the abdominal cavity, where they mature into adults and continue the life cycle.

Dipetalonema streptocerca is primarily found in West Africa and causes a condition known as "cutaneous filariasis" or "subcutaneous filariasis." This species has a similar life cycle to D. perstans, but it involves biting midges (culicoides) instead of mosquitoes as intermediate hosts. The adult worms reside in the subcutaneous tissue, where they produce microfilariae that circulate in the skin. Infective larvae develop inside the biting midge and are transmitted to humans during blood feeding.

The symptoms of Dipetalonema infections can vary widely depending on the species and the severity of the infection. Some people may not experience any symptoms, while others may have fever, cough, wheezing, skin rashes, or lymphatic swelling (lymphedema). Treatment typically involves administration of anti-parasitic drugs such as diethylcarbamazine or ivermectin.

RNA (Ribonucleic acid) is a single-stranded molecule that plays a crucial role in the process of gene expression. It acts as a messenger carrying genetic information copied from DNA to the ribosomes, where proteins are synthesized. RNA is also involved in catalyzing chemical reactions and regulating gene expression.

Helminths, on the other hand, refer to parasitic worms that infect humans and animals. They belong to various phyla, including Nematoda (roundworms), Platyhelminthes (flatworms), and Acanthocephala (spiny-headed worms). Helminth infections can cause a range of diseases and conditions, such as intestinal inflammation, anemia, stunted growth, and cognitive impairment.

There is no medical definition for "RNA, Helminth" since RNA is a type of molecule found in all living organisms, including helminths. However, researchers have studied the genetic material of various helminth species to better understand their biology, evolution, and pathogenesis. This includes sequencing and analyzing the RNA transcriptome of these parasites, which can provide insights into their gene expression patterns and help identify potential drug targets for developing new treatments.

Onchocerca is a genus of filarial nematode worms that are the causative agents of onchocerciasis, also known as river blindness. The most common species to infect humans is Onchocerca volvulus. These parasites are transmitted through the bite of infected blackflies (Simulium spp.) that breed in fast-flowing rivers and streams.

The adult female worms live in nodules beneath the skin, while the microfilariae, which are released by the females, migrate throughout various tissues, including the eyes, where they can cause inflammation and scarring, potentially leading to blindness if left untreated. The infection is primarily found in Africa, with some foci in Central and South America. Onchocerciasis is considered a neglected tropical disease by the World Health Organization (WHO).

A helminth genome refers to the complete set of genetic information present in the DNA of a helminth organism. Helminths are parasitic worms that include nematodes (roundworms), cestodes (tapeworms), and trematodes (flukes). The genome of a helminth includes all of the genes that code for proteins, as well as non-coding DNA sequences that regulate gene expression and other functions.

The study of helminth genomics has provided important insights into the biology and evolution of these parasites, as well as their interactions with their hosts. For example, genomic studies have identified potential drug targets and vaccine candidates, and have helped to elucidate the mechanisms of host-parasite coevolution.

It's worth noting that the size and complexity of helminth genomes can vary widely depending on the species. Some helminth genomes are relatively small and compact, while others are large and complex, with a high degree of genetic diversity. The human whipworm (Trichuris trichiura), for example, has a genome size of approximately 120 megabases, while the tapeworm Schistosoma mansoni has a genome size of over 360 megabases.

Overall, the study of helminth genomics is an important area of research that has the potential to inform the development of new strategies for preventing and treating helminth infections, which affect millions of people worldwide.

Aspartate-tRNA ligase is an enzyme that plays a crucial role in protein synthesis. Its specific function is to join the amino acid aspartic acid to its corresponding transfer RNA (tRNA) molecule, forming an aspartyl-tRNA complex. This complex is essential for the accurate translation of genetic information encoded in messenger RNA (mRNA) into a polypeptide chain during protein synthesis.

The systematic name for this enzyme is L-aspartate:tRNA(Asn) ligase (AMP-forming), which reflects its role in catalyzing the reaction between aspartic acid and tRNA(Asn). The enzyme can also activate aspartic acid by forming an aspartyl-AMP intermediate before transferring the activated aspartate to the appropriate tRNA molecule.

Deficiencies or mutations in aspartate-tRNA ligase can lead to various genetic disorders and impairments in protein synthesis, which may have severe consequences for cellular function and overall health.

'Murinae' is not a medical term. It is a taxonomic classification used in biology, specifically for a subfamily of rodents that includes mice, rats, and several related species. The term 'Murinae' comes from the family Muridae, which is the largest family of mammals, containing over 700 species.

The misconception might arise because medical professionals sometimes use common names for various animals or organisms in their diagnoses, treatments, or research. However, it is essential to clarify that 'Murinae' is a scientific classification and not a medical term.

A larva is a distinct stage in the life cycle of various insects, mites, and other arthropods during which they undergo significant metamorphosis before becoming adults. In a medical context, larvae are known for their role in certain parasitic infections. Specifically, some helminth (parasitic worm) species use larval forms to infect human hosts. These invasions may lead to conditions such as cutaneous larva migrans, visceral larva migrans, or gnathostomiasis, depending on the specific parasite involved and the location of the infection within the body.

The larval stage is characterized by its markedly different morphology and behavior compared to the adult form. Larvae often have a distinct appearance, featuring unsegmented bodies, simple sense organs, and undeveloped digestive systems. They are typically adapted for a specific mode of life, such as free-living or parasitic existence, and rely on external sources of nutrition for their development.

In the context of helminth infections, larvae may be transmitted to humans through various routes, including ingestion of contaminated food or water, direct skin contact with infective stages, or transmission via an intermediate host (such as a vector). Once inside the human body, these parasitic larvae can cause tissue damage and provoke immune responses, leading to the clinical manifestations of disease.

It is essential to distinguish between the medical definition of 'larva' and its broader usage in biology and zoology. In those fields, 'larva' refers to any juvenile form that undergoes metamorphosis before reaching adulthood, regardless of whether it is parasitic or not.

Genes are the fundamental units of heredity in living organisms. They are made up of DNA (deoxyribonucleic acid) and are located on chromosomes. Genes carry the instructions for the development and function of an organism, including its physical and behavioral traits.

Helminths, also known as parasitic worms, are a type of parasite that can infect various organs and tissues in humans and animals. They have complex life cycles that involve multiple hosts and stages of development. Examples of helminths include roundworms, tapeworms, and flukes.

In the context of genetics, genes from helminths are studied to understand their role in the biology and evolution of these parasites, as well as to identify potential targets for the development of new drugs or vaccines to control or eliminate helminth infections. This involves studying the genetic makeup of helminths, including their DNA, RNA, and proteins, and how they interact with their hosts and the environment.

Nematoda is a phylum of pseudocoelomate, unsegmented worms with a round or filiform body shape. They are commonly known as roundworms or threadworms. Nematodes are among the most diverse and numerous animals on earth, with estimates of over 1 million species, of which only about 25,000 have been described.

Nematodes are found in a wide range of habitats, including marine, freshwater, and terrestrial environments. Some nematode species are free-living, while others are parasitic, infecting a variety of hosts, including plants, animals, and humans. Parasitic nematodes can cause significant disease and economic losses in agriculture, livestock production, and human health.

The medical importance of nematodes lies primarily in their role as parasites that infect humans and animals. Some common examples of medically important nematodes include:

* Ascaris lumbricoides (human roundworm)
* Trichuris trichiura (whipworm)
* Ancylostoma duodenale and Necator americanus (hookworms)
* Enterobius vermicularis (pinworm or threadworm)
* Wuchereria bancrofti, Brugia malayi, and Loa loa (filarial nematodes that cause lymphatic filariasis, onchocerciasis, and loiasis, respectively)

Nematode infections can cause a range of clinical symptoms, depending on the species and the location of the parasite in the body. Common symptoms include gastrointestinal disturbances, anemia, skin rashes, and lymphatic swelling. In some cases, nematode infections can lead to serious complications or even death if left untreated.

Medical management of nematode infections typically involves the use of anthelmintic drugs, which are medications that kill or expel parasitic worms from the body. The choice of drug depends on the species of nematode and the severity of the infection. In some cases, preventive measures such as improved sanitation and hygiene can help reduce the risk of nematode infections.

'Culicidae' is the biological family that includes all species of mosquitoes. It consists of three subfamilies: Anophelinae, Culicinae, and Toxorhynchitinae. Mosquitoes are small, midge-like flies that are known for their ability to transmit various diseases to humans and other animals, such as malaria, yellow fever, dengue fever, and Zika virus. The medical importance of Culicidae comes from the fact that only female mosquitoes require blood meals to lay eggs, and during this process, they can transmit pathogens between hosts.

Trans-splicing is a process in which two different RNA molecules are spliced together to form a single, chimeric RNA molecule. This process involves the removal of introns (non-coding sequences) from both RNA molecules and the ligation of the remaining exons (coding sequences) to create a new RNA molecule that contains genetic information from both original RNAs.

In cis-splicing, which is the more common form of splicing, introns are removed and exons are ligated within the same RNA molecule. However, in trans-splicing, the exons to be ligated come from two separate RNA molecules that have been transcribed from different genes or different regions of the same gene.

Trans-splicing is found in a variety of organisms, including some higher eukaryotes such as humans, where it plays a role in generating genetic diversity and regulating gene expression. It can also occur in certain viruses, where it is used to generate new mRNA molecules that encode for essential viral proteins.

Host-parasite interactions refer to the relationship between a parasitic organism (the parasite) and its host, which can be an animal, plant, or human body. The parasite lives on or inside the host and derives nutrients from it, often causing harm in the process. This interaction can range from relatively benign to severe, depending on various factors such as the species of the parasite, the immune response of the host, and the duration of infection.

The host-parasite relationship is often categorized based on the degree of harm caused to the host. Parasites that cause little to no harm are called commensals, while those that cause significant damage or disease are called parasitic pathogens. Some parasites can even manipulate their hosts' behavior and physiology to enhance their own survival and reproduction, leading to complex interactions between the two organisms.

Understanding host-parasite interactions is crucial for developing effective strategies to prevent and treat parasitic infections, as well as for understanding the ecological relationships between different species in natural ecosystems.

"Caenorhabditis" is a genus of nematode (roundworm) animals, which are commonly used as model organisms in scientific research. The most widely studied species within this genus is "Caenorhabditis elegans," which has been extensively researched due to its simple anatomy, short lifespan, and fully sequenced genome. These nematodes are found in various environments, including soil and decaying organic matter, and play a crucial role in the decomposition process. The term "Caenorhabditis" itself is derived from Greek roots, with "caeno" meaning "recent" or "new," and "rhabditis" referring to the shape of their tails.

I'm sorry for any confusion, but "Indonesia" is not a medical term. It is a country located in Southeast Asia and Oceania, between the Indian and Pacific oceans. It is the world's largest island country, with more than thirteen thousand islands. If you have any questions about medical terms or concepts, I would be happy to help with those!

"Spliced leader RNA (SL-RNA)" is a type of RNA molecule that is present in some single-celled eukaryotic organisms, such as trypanosomes and nematodes. In these organisms, spliced leader RNAs play a critical role in the process of gene expression by providing a "leader" sequence that is added to the beginning of messenger RNA (mRNA) molecules during the process of RNA splicing.

SL-RNAs are typically composed of two regions: a conserved 5' " leader" sequence, which is added to the beginning of mRNAs, and a variable 3' " trailer" sequence, which contains the sequences required for recognition and cleavage by the splicing machinery. During RNA splicing, the spliced leader RNA is joined to the target mRNA through a process called trans-splicing, in which the leader sequence of the SL-RNA is ligated to the 5' end of the target mRNA, replacing the original 5' exon.

The addition of the spliced leader sequence to mRNAs can have several important consequences for gene expression. For example, it can help ensure that all mRNAs produced from a given gene contain the same 5' end, even if the gene is transcribed from multiple promoters or undergoes alternative splicing. Additionally, the presence of the conserved leader sequence can serve as a recognition site for RNA-binding proteins, which can regulate mRNA stability, localization, and translation.

Overall, spliced leader RNAs are an important component of the gene expression machinery in many eukaryotic organisms, and their study has provided valuable insights into the mechanisms of RNA processing and regulation.

Trichlorfon is an organophosphate insecticide and acaricide. It is used to control a wide variety of pests, including flies, ticks, and mites in agriculture, livestock production, and public health. Trichlorfon works by inhibiting the enzyme acetylcholinesterase, which leads to an accumulation of the neurotransmitter acetylcholine and results in paralysis and death of the pest. It is important to note that trichlorfon can also have harmful effects on non-target organisms, including humans, and its use is regulated by various governmental agencies to minimize potential risks.

In the context of medicine and biology, symbiosis is a type of close and long-term biological interaction between two different biological organisms. Generally, one organism, called the symbiont, lives inside or on another organism, called the host. This interaction can be mutually beneficial (mutualistic), harmful to the host organism (parasitic), or have no effect on either organism (commensal).

Examples of mutualistic symbiotic relationships in humans include the bacteria that live in our gut and help us digest food, as well as the algae that live inside corals and provide them with nutrients. Parasitic symbioses, on the other hand, involve organisms like viruses or parasitic worms that live inside a host and cause harm to it.

It's worth noting that while the term "symbiosis" is often used in popular culture to refer to any close relationship between two organisms, in scientific contexts it has a more specific meaning related to long-term biological interactions.

... malayi and Brugia timori cause lymphatic filariasis in humans; and Brugia pahangi and Brugia patei infect domestic cats ... Vincent, Albert L.; Frommes, Stephen P.; Ash, Lawrence R. (1976). "Brugia malayi, Brugia pahangi, and Brugia patei: Pulmonary ... Brugia roundworms are small, measuring less than a centimetre. The longest female is 60 mm long and 0.19 mm wide, and male is ... Brugia is a genus for a group of small roundworms. They are among roundworms that cause the parasitic disease filariasis. ...
The microfilariae of Brugia timori are longer and morphologically distinct from those of Brugia malayi and Wuchereria bancrofti ... The life cycle of Brugia timori is very similar to that of Wuchereria bancrofti and Brugia malayi, leading to nocturnal ... Aside from vectoring Brugia species, mosquitoes also maintain Wolbachia spp. which has been found to be an obligate ... Brugia timori is a filarial (arthropod-borne) nematode (roundworm) which causes the disease "Timor filariasis", or "Timorian ...
... ". Edeson, J. F. B. & Wilson, T. (1964), "The epidemiology of filariasis due to Wuchereria Bancrofti and Brugia ... "Brugia malayi". Web Atlas of Medical Parasitology. "Bench aids for the diagnosis of filarial infections. Plate 2 - Brugia ... "Brugia malayi". American Association of Veterinary Parasitologists. 2010-01-01. Retrieved 2022-01-16. "Life cycle of Brugia ... Brugia malayi is a filarial (arthropod-borne) nematode (roundworm), one of the three causative agents of lymphatic filariasis ...
... is a parasitic roundworm belonging to the genus Brugia. It is a filarial nematode known to infect the lymph ... Leoaquarius, Sreejith (January 11, 2014). "Brugia pahangi & brugia beaveri". Slideshare. Retrieved 2016-12-26. Kambris, Z; Cook ... In the Brugia genus, there are two spicules, they are the shortest in length, the left one being 200-215 μm and the right one ... This genus of Brugia is most commonly recognized by the spicules in males, which are needle like mating structures that open ...
"Brugia (1062227)". Miramar Ship Index. Retrieved 10 February 2020. "ABANDON BURNING VESSEL IN MIDST OF HOWLING GALE Captain ...
2016 Global Alitalia video campaign directed by Federico Brugia; Michael Haussman's video for Galbani France; video clip ...
Brugia malayi causes most of the remainder of the cases, while Brugia timori is a rare cause. W. bancrofti largely affects ... Three types of worms are known to cause the disease: Wuchereria bancrofti, Brugia malayi, and Brugia timori, with Wuchereria ... Brugia malayi, and Brugia timori. The filarial roundworms are transmitted by the bite of an infected mosquito of genera Aedes, ... On 20 September 2007, geneticists published the first draft of the complete genome (genetic content) of Brugia malayi, one of ...
September 2007). "Draft genome of the filarial nematode parasite Brugia malayi". Science. 317 (5845): 1756-60. Bibcode:2007Sci ... Brugia malayi (Strain:TRS), human-infecting filarial parasite (2007) Bursaphelenchus xylophilus, infects pine trees (2011) ...
It is a vector of nocturnally subperiodic Brugia malayi. Females are known to be strongly anthropophilic (human biters). Larvae ... to nocturnally subperiodic Brugia malayi (Spirurida: Filariodea)". J Med Entomol. 39: 215-7. PMID 11931259. "Bionomics". ENVIS ...
"Mining predicted essential genes of Brugia malayi for nematode drug targets". PLOS ONE. 2 (11): e1189. Bibcode:2007PLoSO... ...
Nandi NC (1982). "Brugia-type microfilariae in the Madras tree shrew Anathana ellioti (Waterhouse)". J. Helminthol. 56 (2): 93- ...
Roundworms such as Brugia, Wuchereria and Onchocerca are directly transmitted by mosquitoes. In the developing world, the use ... Brugia malayi infection) Onchocerciasis (Onchocerca volvulus infection) Soil-transmitted helminthiasis - this includes ...
The second Wolbachia genome to be determined was of strain wBm, which infects Brugia malayi nematodes. Genome sequencing ... April 2005). "The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode". PLOS Biology. ... April 2005). "The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode". PLOS Biology. ... In the parasitic filarial nematode species responsible for elephantiasis, such as Brugia malayi and Wuchereria bancrofti, ...
2005). "The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode". PLOS Biol. 3 (4): ...
Brugia malayi: Proteomic profile of adult excretory-secretory products". Molecular and Biochemical Parasitology. 160 (1): 8-21 ...
In the Domesday Book the town is listed as Brugie, while Brugia was also used. After the Norman invasion the land was given to ...
While posted in Hanoi, he made major advances in the study of Brugia malayi and strongyloidiasis. He also noted how ...
A 2019 report identified dogs in Kerala who have another worm which can cause filariasis, Brugia malayi. This worm is not known ... Sadarama, PV; Chirayath, D; Pillai, UN; Unny, NM; Lakshmanan, B; Sunanda, C (December 2019). "Canine Brugia malayi ...
"Field and laboratory observations on Coquillettidia crassipes in relation to transmission of Brugia malayi in Peninsular ...
His current research focuses on enteric fever and on a rapid antigen detection test for brugia malayi. Honorary Member of ...
It is a natural vector for filarial worms such as zoonotic Brugia pahangi, and Wuchereria bancrofti, which cause filariasis to ... "Armigeres subalbatus incriminated as a vector of zoonotic Brugia pahangi filariasis in suburban Kuala Lumpur, Peninsular ...
Brugia malayi, and Brugia timori. Tropical pulmonary eosinophilia is a rare syndrome characterised by pulmonary interstitial ... The syndrome is caused by a distinct hypersensitive immunological reaction to microfilariae of W. bancrofti and Brugia malayi. ...
Compared to infections with other filarial parasites such as Wuchereria bancrofti, Brugia malayi, and Loa loa, Mansonella ... and Brugia malayi. The dependence of these parasites on their endosymbionts has led to the use of antibiotics directed against ...
... other species are secondary or suspected vectors of Brugia malayi the cause of lymphatic filariasis, and Rift Valley fever. ...
There is evidence it is a vector for Japanese encephalitis, as well as the roundworm Brugia malayi in Thailand. Norbert Becker ...
"Immunization of Mastomys coucha with Brugia malayi Recombinant Trehalose-6-Phosphate Phosphatase Results in Significant ...
It shows a high affinity for human biting and is a potent vector of Brugia malayi to cause Malayan filariasis. In 1980, The ... Natural Mortality of Mansonia annulifera with Special Reference to Mortality due to Brugia malayi Infection and Distribution of ...
In 2013 Italian director Federico Brugia cast Northover as the villain in his feature debut Tutti i rumori del mare. Set in the ...
The video, shot in black and white, was directed by Federico Brugia and produced by Nick Verden for Stark Naked Films. It was ...
Brugia malayi, and Brugia timori. These worms occupy the lymphatic system, including the lymph nodes; in chronic cases, these ... while Brugia timori rarely affects the genitals.[citation needed] Those who develop the chronic stages of elephantiasis are ...
Brugia malayi and Brugia timori cause lymphatic filariasis in humans; and Brugia pahangi and Brugia patei infect domestic cats ... Vincent, Albert L.; Frommes, Stephen P.; Ash, Lawrence R. (1976). "Brugia malayi, Brugia pahangi, and Brugia patei: Pulmonary ... Brugia roundworms are small, measuring less than a centimetre. The longest female is 60 mm long and 0.19 mm wide, and male is ... Brugia is a genus for a group of small roundworms. They are among roundworms that cause the parasitic disease filariasis. ...
Record suppressed. This record was removed as a result of standard genome annotation processing. Please see www.ncbi.nlm.nih.gov/genome/annotation_euk/process/ for more information. ...
World Health Organization. Regional Office for the Western Pacific (‎WHO Regional Office for the Western Pacific, 1985)‎ ...
Zoonotic Brugia infection in western Michigan M L Eberhard 1 , L J DeMeester, B W Martin, P J Lammie ... Zoonotic Brugia infection in western Michigan M L Eberhard et al. Am J Surg Pathol. 1993 Oct. ... Zoonotic Brugia infections in North and South America. Orihel TC, Beaver PC. Orihel TC, et al. Am J Trop Med Hyg. 1989 Jun;40(6 ... Molecular Characterization of a Reemergent Brugia malayi Parasite in Sri Lanka, Suggestive of a Novel Strain. Mallawarachchi CH ...
BRUGIA MALAYI (UNII: V1NN02KTF0) (BRUGIA MALAYI - UNII:V1NN02KTF0) BRUGIA MALAYI. 39 [hp_C] in 1 mL. ... Artemisia Vulgaris 2X, Ascaris Lumbricoides 15X, 30X, 60X, 200X, Brugia Malayi 39C, 60C, 200C, Calcarea Carbonica 12X, Cina 8X ... Label: VER (artemisia vulgaris, ascaris lumbricoides, brugia malayi, calcarea carbonica, cina, cryptosporidium parvum, ... VER (artemisia vulgaris, ascaris lumbricoides, brugia malayi, calcarea carbonica, cina, cryptosporidium parvum, enterobius ...
Stage specific gene expression in the post-infective L3 of the filarial nematode, Brugia pahangi ... Brugia pahangi. Molecular and Biochemical Parasitology, 79(1), pp. 109-112. (doi: 10.1016/0166-6851(96)02637-0) (PMID:8844678) ...
... we first reported the lipid profile of adult Brugia malayi using ultra-performance liquid chromatography electrospray ... Lipid biomarker profiling of adult Brugia malayi using mass spectrometry detection. Niyomploy P., Mangmee S., Tipthara P., ... In this article, we first reported the lipid profile of adult Brugia malayi using ultra-performance liquid chromatography ...
... for Bm1770k from Brugia malayi WS250. Plus protein sequence and external database links. ...
Brugia malayi adults in tissue. Brugia spp. have typical features of filarial nematodes in cross-section. Females reach a ... Microfilariae of Brugia malayi. Microfilariae of Brugia malayi are sheathed and in stained blood smears measure 175-230 µm. In ... Microfilaria of Brugia timori are sheathed and measure on average 310 µm in stained blood smears and 340 µm in 2% formalin. ... Brugia timori is restricted to the Lesser Sunda Islands of Indonesia.. Clinical Features. While severe manifestations do not ...
Lonely Planet Pocket Bruges & Brussels is your passport to the most relevant, up-to-date advice on what to see and skip, and what hidden discoveries await you in Bruges and Brussels.
Cultivation of Sexually Mature Brugia malayi In Vitro Riberu WA., Bangs MJ., Tirtokusumo S., Atmosoedjono S., Baird JK., ...
Ile muszę mieć lat, aby wynająć samochód w Brugia. Aby wynająć samochód w Brugia, musisz mieć co najmniej 21 lat, a w przypadku ... Jaki typ samochodu najlepiej nadaje się na wakacje w Brugia?. Wybierając samochód do wynajęcia w Brugia, ważne jest, aby wziąć ... Czy odbiorę samochód na lotnisku w Brugia?. Większość naszych Brugia wypożyczalni samochodów zapewnia odbiór i dowóz na ... Copyright 2002 - 2023 Brugia Car Rental Guide Bruges-car-rental.com jest częścią , której właścicielem jest Ecommerce Group LTD ...
... for Bm3988b from Brugia malayi WS250. Plus protein sequence and external database links. ...
Brugia spp. adults.Adults are allowed to recover in complete media after extraction and (if applicable) shipment in order ... phenotypic drug screens against Brugia spp. adults. ...
The Domestic Dog as a Laboratory Host for Brugia malayi Donna Huber on September 21, 2022 ... Of the three nematodes responsible for lymphatic filariasis in humans, only Brugia malayi is actively maintained in research ... Recognition and killing of Brugia malayi microfilariae by human immune cells is dependent on the parasite sample and is not ... Attachment of human neutrophils and monocytes to Brugia malayi microfilaria precedes parasite killing. ...
The epidemiology and treatment of infection due to Brugia malayi*  Edeson, J. F. B. (‎1962)‎ ...
Brugia spp. Rodents, carnivores. Vectorborne (mosquitoes). Lymphatic tissue. Histopathology. Gnathostoma spinigerum Cats. ...
Brugia malayi. Listeria monocytogenes. Dengue. Loa loa. Parvovirus. Onchocerca volvulus. Syphilis. Trichinella spiralis. ...
A modern day thriller set in the bleak underworld of the Hungarian and Italian human trafficking business.
Brugia timori. The worms affect the lymphatic system in the body. The lymphatic system is responsible for removing waste and ...
Brugia malayi,/i,, its ,i,Wolbachia,/i, endosymbiont ,i,w,/i,Bm, and its laboratory vector ,i,Aedes aegypti,/i, … ... Keywords: 6S RNA; Aedes aegypti; Brugia; Brugia malayi; RNA-Seq; Wolbachia; bromodomain; bromodomain inhibitor; drug ... Brugia malayi, its Wolbachia endosymbiont wBm, and its vector host Aedes aegypti at 16 distinct B. malayi life stages. B. ... on the filarial nematode Brugia malayi, its Wolbachia endosymbiont wBm, and its laboratory vector Aedes aegypti across the ...
Paul R, Ilamaran M, Khatri V, Amdare N, Reddy MVR, Kaliraj P. Immunological evaluation of fusion protein of Brugia malayi ... Paul, R, Ilamaran, M, Khatri, V, Amdare, N, Reddy, MVR & Kaliraj, P 2019, Immunological evaluation of fusion protein of Brugia ... T1 - Immunological evaluation of fusion protein of Brugia malayi abundant larval protein transcript-2 (BmALT-2) and Tuftsin in ... Immunological evaluation of fusion protein of Brugia malayi abundant larval protein transcript-2 (BmALT-2) and Tuftsin in ...
Brugia malayi nematode.. Technique gallery. Polarized Light Microscopy. Metamorphic rock.. Technique gallery. ...
... introduction Mara Brugia, Cedefop 4. Session 3 - Expanding the network to include the New Member States - Review of the process ... and main issues Mara Brugia, TTnet Coordinator, Cedefop ... Introduction to the TTnet thematic projects Mara Brugia, ... Mara Brugia, Cedefop 4. Session 3 - Expanding the network to include the New Member States - Review of the process and main ... Mara Brugia, Cedefop 2. Session 1 - Professionalisation of VET teachers for the future - outline of the PROFF project Kristiina ...
Wuchereria bancrofti and Brugia malayi are the causative agents of lymphatic filariasis and Onchocerca volvulus causes ... Voronin D*, Schnall E, Grote A, Jawahar S, Ali W, Unnasch TR, Ghedin E, Lustigman S. Pyruvate produced by Brugia spp. via ... Grote A, Voronin D, Ding T, Twaddle A, Unnasch TR, Lustigman S, Ghedin E. Defining Brugia malayi and Wolbachia symbiosis by ... Taylor, he obtained a Bill and Melinda Gates Foundation Grand Challenges Explorations grant to use Brugia malayis own ...
Dear Brugia:. 1- About 15 years. 2- That I was going into an ocean of troubles and an enormous amount of work. I was right.. 3 ...
Effects of diethylcarbamazine and ivermectin treatment on Brugia malayi gene expression in infected gerbils (Meriones ...

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