The inner layer of CHOROID, also called the lamina basalis choroideae, located adjacent to the RETINAL PIGMENT EPITHELIUM; (RPE) of the EYE. It is a membrane composed of the basement membranes of the choriocapillaris ENDOTHELIUM and that of the RPE. The membrane stops at the OPTIC NERVE, as does the RPE.
It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)
A publication issued at stated, more or less regular, intervals.
A surgical specialty concerned with the structure and function of the eye and the medical and surgical treatment of its defects and diseases.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
Further or repeated use of equipment, instruments, devices, or materials. It includes additional use regardless of the original intent of the producer as to disposability or durability. It does not include the repeated use of fluids or solutions.
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.
The portion of the optic nerve seen in the fundus with the ophthalmoscope. It is formed by the meeting of all the retinal ganglion cell axons as they enter the optic nerve.
Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM.
A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.
The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.
Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
Methods, procedures, and tests performed to diagnose disease, disordered function, or disability.
The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.
The layer of pigment-containing epithelial cells in the RETINA; the CILIARY BODY; and the IRIS in the eye.
The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.
Studies beyond the bachelor's degree at an institution having graduate programs for the purpose of preparing for entrance into a specific field, and obtaining a higher degree.
A large family of narrow-leaved herbaceous grasses of the order Cyperales, subclass Commelinidae, class Liliopsida (monocotyledons). Food grains (EDIBLE GRAIN) come from members of this family. RHINITIS, ALLERGIC, SEASONAL can be induced by POLLEN of many of the grasses.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA.
The innermost membranous sac that surrounds and protects the developing embryo which is bathed in the AMNIOTIC FLUID. Amnion cells are secretory EPITHELIAL CELLS and contribute to the amniotic fluid.
Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.

Repopulation of different layers of host human Bruch's membrane by retinal pigment epithelial cell grafts. (1/198)

PURPOSE: To determine the morphology of human retinal pigment epithelium (RPE) after reattachment to different ultrastructural layers of human Bruch's membrane (BM). METHODS: Bruch's membrane explants were prepared from eyes of 23 human donors (age range, 11-89 years). The basal lamina of the RPE, inner collagenous layer, and elastin layer were removed sequentially by mechanical and enzymatic techniques. First-passage cells of human RPE (15,000 cells/6 mm explant) from three donors (ages, 52, 64, and 80 years) were plated onto different layers of human BM, and the explants were examined by scanning and transmission electron microscopy up to 21 days later. RESULTS: RPE flattened and extended footplates 6 hours after plating onto basal lamina. Cells remained round 6 and 24 hours after plating onto the inner collagenous, elastin, or outer collagenous layer. The RPE cells became confluent 14 days after plating onto basal lamina but did not become confluent up to 21 days after plating onto the inner collagenous or elastin layer. Sparse round cells were observed 21 days after plating onto deeper layers, suggesting extensive loss of RPE. CONCLUSIONS: The morphology and subsequent behavior of the RPE reattached to BM depends on the anatomic layer of BM available for cell reattachment. The results suggest that the ability of transplanted RPE to repopulate BM in age-related macular degeneration and other disorders may depend on the layer of BM available to serve as a substrate for cell reattachment.  (+info)

Increase in the advanced glycation end product pentosidine in Bruch's membrane with age. (2/198)

PURPOSE: To determine whether there is an age-related increase of pentosidine in human Bruch's membranes and to localize pentosidine and carboxymethyllysine (CML), two well-characterized, advanced glycation end products (AGEs) in aged human Bruch's membranes and choroid in vivo. METHODS: Human Bruch's membrane samples were isolated from the retinal pigment epithelium (RPE) and choroid and subjected to reversed-phase high-performance liquid chromatography to determine pentosidine content. A polyclonal anti-pentosidine antibody and a monoclonal antibody specific for carboxymethyllysine were used to localize AGEs in 20-month-old nondiabetic, 82-year-old nondiabetic, and 82-year-old diabetic globes. RESULTS: Human Bruch's membranes (n = 20) showed a linear age-dependent increase in pentosidine that reached approximately 0.17 millimoles pentosidine per mole hydroxyproline in late life (r = 0.896; P < 0.001). Immunohistochemical evaluation showed evidence of pentosidine in Bruch's membrane, choroidal extracellular matrix, and vessel walls in the 82-year-old nondiabetic and diabetic globes. A similar staining pattern was found with the anti-CML antibody. Basal laminar deposits and drusen stained with both antibodies in the elderly nondiabetic eye. In contrast, neither antibody stained the 20-month-old tissue. CONCLUSIONS: We provide biochemical and immunohistochemical evidence for the formation of pentosidine and CML structures in human Bruch's membrane and choroid with age. These changes could promote aging of the RPE-Bruch's membrane-choroid complex.  (+info)

Early drusen formation in the normal and aging eye and their relation to age related maculopathy: a clinicopathological study. (3/198)

AIM: To describe the early formation of drusen and their relation to normal aging changes at the macula and to the development of age related maculopathy (ARM). METHOD: Histopathological features of 353 eyes without histological evidence of ARM are described and correlated with the clinical appearance. In addition, 45 of these eyes were examined by transmission electron microscopy. RESULTS: Drusen were detected histopathologically in 177 (50%) eyes but were seen clinically in only 34% of these. Drusen were mainly small hard drusen with an occasional soft distinct drusen: no soft indistinct drusen were seen. Only those drusen deposits larger than 25-30 microns in diameter were detectable clinically. Preclinical drusen in eyes with only an occasional drusen were seen on electron microscopy as entrapment sites of coated membrane bound bodies which formed adjacent to the inner collagenous zone of Bruch's membrane. In contrast, preclinical drusen deposits in eyes with many drusen were seen as accumulations of amorphous material which appeared hyalinised by light microscopy. A distinct feature were rows of dense hyalinised microdrusen (1-2 microns in diameter), over which larger globular hyalinised drusen formed. CONCLUSION: Histological and ultrastructural examination can recognise and distinguish the earliest drusen formed as a result of normal aging from those associated with ARM. In eyes without diffuse deposits, histologically all drusen were of the hard hyalinised variety or their derivatives; no soft drusen composed of membranous debris were found. These findings support and explain those of other authors who do not consider the presence of a few small hard drusen to be a risk factor for the development of ARM.  (+info)

Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye. (4/198)

PURPOSE: To develop an antibody that recognizes a variety of advanced glycation endproduct (AGE) epitopes. METHODS: Glycolaldehyde was used to modify bovine serum albumin and HPLC analysis was used to measure pentosidine formation as an indicator of AGE formation. A polyclonal anti-AGE antibody was synthesized by injecting glycolaldehyde-incubated keyhole limpet hemocyanin into rabbits, affinity purified using AGE modified bovine serum albumin coupled to an affinity resin column, and characterized by immunoblot analysis. RESULTS: HPLC analysis of glycolaldehyde treated bovine serum albumin detected high levels of pentosidine formation, suggesting that glycolaldehyde is a potent precursor for pentosidine. By immunoblot analysis, our antibody recognized carboxymethyllysine and pentosidine, two well-characterized AGEs, as well as other AGE epitopes. Immunohistochemical evaluation showed evidence of AGEs in Bruch's membrane (including basal laminar deposits and drusen), choroidal extracellular matrix, and vessel walls in an 82 year old nondiabetic globe. A similar staining pattern was observed in an age-matched diabetic control. In contrast, no staining was seen with the antibody in a 20 month old nondiabetic globe. CONCLUSIONS: A unique anti-AGE antibody was synthesized that recognizes a variety of AGE epitopes including carboxymethyllysine and pentosidine. Its best use might be in broad surveys of the age-dependent accumulation of a large number of AGE epitopes that might not be revealed by antibodies to pentosidine or CML.  (+info)

TIMP-3 in Bruch's membrane: changes during aging and in age-related macular degeneration. (5/198)

PURPOSE: To assess the distribution, content, and function of tissue inhibitor of metalloproteinases (TIMP)-3 during aging in normal eyes for comparison with the levels observed in eyes with age-related macular degeneration (AMD). METHODS: Donor tissues analyzed included 36 normal eyes (14-96 years old) and 15 AMD eyes (74 -98 years old). A tissue strip including the fovea was used for immunohistochemistry. Western blot analysis was performed on extracts of the retinal pigment epithelium (RPE)- choroid complex from the posterior part of each eye. Immunoreactivity of TIMP-3 bands in each western blot was densitometrically quantitated. The inhibitory function of TIMP-3 was evaluated with reverse zymography. RESULTS: TIMP-3 was present uniformly across Bruch's membrane in the normal samples. In samples from donors more than 50 years of age, immunostaining was intense. TIMP-3 content ranged from 92 to 1061 ng/cm2 and increased with age (r = 0.66). In AMD eyes, TIMP-3 distribution in Bruch's membrane was abundant in areas of continuous soft drusen but absent in areas below RPE atrophy. TIMP-3 levels in AMD eyes were significantly higher than in age-matched normal eyes (577 versus 877 ng/cm2; P = 0.009). Inhibitory activity correlated well with TIMP-3 content (r = 0.82) and was also significantly higher in AMD eyes than in age-matched normal eyes (P < 0.001). CONCLUSIONS: During normal aging, TIMP-3 content in Bruch's membrane of the macula shows a significant increase. TIMP-3 content in AMD eyes was elevated relative to that of age-matched normal eyes. Higher levels of TIMP-3 may contribute to the thickening of Bruch's membrane observed in AMD.  (+info)

Age-dependent variation in metalloproteinase activity of isolated human Bruch's membrane and choroid. (6/198)

PURPOSE: To characterize and determine the effect of aging on the matrix metalloproteinase (MMP) component of the extracellular matrix-remodeling mechanism of isolated human Bruch's-choroid. METHODS: Immunohistochemical techniques and western blot analysis were used to detect and localize various members of the MMP family of proteolytic enzymes in the Bruch's-choroid complex. Gelatin substrate zymography was used to detect and quantify the levels of MMP-2 and -9 in homogenates of Bruch's-choroid from both macular and peripheral regions of the human fundus. Aging alterations in these enzymes were quantified by densitometric analysis of photographic negatives of the zymography gels. RESULTS: Intact preparations of Bruch's-choroid showed the presence of inactive forms of two gelatinases (MMP-2, 65 kDa, and MMP-9, 92 kDa), interstitial collagenase (MMP-1, 52 kDa) and stromelysin (MMP-3, 57 kDa). MMP-1 and -3 were localized primarily to Bruch's membrane. MMP-9 was distributed evenly in Bruch's membrane with some patchy presence in the choroidal mass. Distribution of MMP-2 was similar to that of MMP-9, but the staining in Bruch's was much fainter. On gelatin zymography, an active form of MMP-2 (58-kDa species) was frequently observed in peripheral samples but only occasionally in macular regions. The levels of MMP-2 and -9 increased with aging in both the macular and the peripheral regions of the fundus (P < 0.05). MMP-2 levels were lower in macular regions than in the periphery but no such variation was observed with MMP-9. Both these inactive gelatinases could be activated in vitro. CONCLUSIONS: A matrix-degrading mechanism essential for extracellular remodeling was shown to be present in Bruch's membrane. In macular regions, increasing levels of inactive forms of metalloproteinase and scarcity of active forms of MMP-2 suggests possible involvement of impaired extracellular degradation in both aging and macular degeneration.  (+info)

Ultrastructural changes in Bruch's membrane of apolipoprotein E-deficient mice. (7/198)

PURPOSE: To examine the histologic and ultrastructural changes in Bruch's membrane (BM) in apolipoprotein E deficient [ApoE(-)] mice in comparison with age-matched control animals. METHODS: Two-month-old (group 1) and 8-month-old (group 2) normal control C57BL/6 mice and 2-month-old (group 3) and 8-month-old (group 4) ApoE(-) mice were studied. All groups of mice were fed a standard rodent diet. The mice were killed, serum lipid levels were determined, and the eyes were ultrastructurally examined using standard techniques to measure the thickness of BM. The area fraction of electron-lucent (EL) particles in BM was quantified using point-counting stereology. RESULTS: The serum cholesterol levels of the ApoE(-) mice were significantly higher than those of the control mice (P = 0.0001). There was a significant thickening and EL particle accumulation in BM associated with age in the control animals. Group 2 had a thicker BM and more EL particle accumulation than group 1 (P = 0.0410 for thickness; P = 0.0042 for particle accumulation). Age-related changes were not seen in ApoE(-) mice; thickness and accumulation were similar in groups 3 and 4 (P = 0.50, thickness; P approximately/= 1.0, accumulation). Significant thickening and accumulation were seen in young ApoE(-) mice (group 3) versus young control animals (group 1; P = 0.008, thickening; P < 0.0001, EL particle accumulation). Group 4 ApoE(-) mice did not have a thicker BM or more EL particles than group 2 control animals (P = 0.2910, thickness; P = 0.35, EL particle accumulation). "Membrane-bounded" material (material between two membranes) was present significantly more frequently in ApoE(-) mice. CONCLUSIONS: ApoE(-) mice exhibit accumulation of EL particles at an earlier age and have more membrane-bounded material in BM than control mice. This material has ultrastructural similarities to basal linear deposit, which accumulates in age-related maculopathy.  (+info)

Age-related retinal pigment epithelium and Bruch's membrane degeneration in senescence-accelerated mouse. (8/198)

PURPOSE: To investigate age-related changes in the retinal pigment epithelium (RPE), Bruch's membrane, and choriocapillaris in the senescence-accelerated mouse (SAM). METHODS: The external and eyecup features and light and electron microscopic findings were examined in three male and two female mice of a senescence-prone mouse strain (SAM P(8)) monthly for 12 months. These results were compared with those in age-matched mice of similar background but senescence resistant (SAM R(1)). Choroidal vascular casts were prepared at 12 months in seven mice each of the SAM P(8) and SAM R(1) strains. Quantitative analysis of area of choriocapillaris was performed by automated image analysis, and the results were analyzed by paired Student's t-test. RESULTS: We found in the SAM P(8) strain that hair loss, coarseness of hair texture, and ulceration of skin appeared and increased as the age advanced (at approximately 5-9 months). Eyecup examination showed no differences. Light and electron microscopy revealed progressively more prominent abnormalities in the RPE and Bruch's membrane mice older than 10 months. Two of the five SAM P(8) mice older than 11 months showed what appeared to be intra-Bruch's membrane choroidal neovascularization. The RPE and Bruch's membrane appeared normal in the SAM R(1) strain. In the SAM P(8), vascular casts of the choriocapillaris showed a mild but significant decrease in vascular area when compared with the SAM R(1) strain at 12 months (P = 0.011). CONCLUSIONS: Senescence accelerated mice develop progressive age-related changes in the RPE-Bruch's-choriocapillaris complex that have features that may be relevant in the study of age-related macular changes in humans.  (+info)

The purpose of this study is to assess in vivo whether diagnostic lumbar puncture (LP) is followed by optic nerve head (ONH) and parapapillary anatomic changes in normal human eyes. MATERIALS AND METHODS: Prospective, single-center, observational case series. ONH structures (prelaminar tissue surface, anterior surface of the lamina cribrosa, central retinal vessels) and parapapillary structures (internal limiting membrane, posterior surfaces of retinal nerve fiber layer and Bruch membrane/retinal pigment epithelium complex, Bruch membrane opening, posterior surface of the choroid) were quantitatively evaluated by means of swept-source optical coherence tomography (Triton Ver.10.05, Topcon, Tokyo, Japan) before and after LP (5, 60, and 360 min). Each of these structures was manually delineated for measurement before being superimposed to detect any displacement, using peripheral margins of parapapillary structures as a reference plane. RESULTS: A total of 16 eyes of 8 nonglaucomatous patients
The average age of subjects was 30.2 ± 9.3 years for G0 and 29.9 ± 7.1 years for G1 (p = 0.903). Mean sphere was -0.5 ± 0.3 D (-1.25 to 0 D) G0 and -3.9 ± 0.3 D (-6.00 to -3 D) G1 (p,0.001). The RNFL thickness comparison between G0 and G1 showed a significantly lower thickness in G1 (p = 0.018). The BMO-MRW measurements were similar in both groups (p = 0.331). With the BMO-MRW examination, the number of sectors classified as pathologic per subject in G1 were significantly lower compared to RNFL analysis (p = 0.023).. ...
El objetivo de este protocolo es demostrar que el cultivo del pigmento retiniano epitelial (RPE) células en membrana de Bruch humano...
PURPOSE: To correlate postmortem histology with previously recorded multimodal imaging from a patient with type 1 neovascularization (NV) associated with an acquired vitelliform lesion in the setting of age-related macular degeneration (AMD). DESIGN: Case study. METHODS: Multimodal imaging that was obtained antemortem was matched with ex vivo and high-resolution histologic images of the preserved donor macula. Anatomic correlates for multimodal imaging findings were then defined. RESULTS: Spectral-domain optical coherence tomography (OCT) revealed a split in the retinal pigment epithelium-Bruch membrane band. Type 1 NV in this case was composed of 6 layered components: (1) retinal pigment epithelium, (2) basal laminar deposits, (3) fibrovascular membrane, (4) fibrocellular scar, (5) hemorrhage, and (6) Bruch membrane. The anatomic correlates for the hyporeflective band on spectral-domain OCT included a thick basal laminar deposit. Not all structures could be readily separated on the basis of their
Abstract: : Purpose: To determine if EC in normal, aged BrM derives from directly infused plasma low-density lipoprotein (LDL) or from local cells with acyl co-A cholesterol acyl transferase (ACAT)-1 or -2. EC in LDL and EC in cells with ACAT is enriched in cholesteryl linoleate (Ch-18:2) and cholesteryl oleate (Ch-18:1), respectively. Methods: Ch-18:1 and Ch-18:2 were assayed by mass spectrometry in macular BrM, cornea, and sclera (10 donor eyes, greater than 60 yr), cholesterol-enriched human monocyte-macrophages, and LDL. Ch-16:0 (palmitate), Ch-18:0 (stearate), Ch-18:1, Ch-18:2, Ch-20:4 (arachidonate) and the corresponding free fatty acids (FFA) were assayed in macular BrM and RPE (n=6). Lipids were extracted with chloroform and methanol and separated by reversed phase HPLC using an isopropanol gradient in 10 mM ammonium acetate. Ion mass spectra (positive for ammonium ion adducts of cholesteryl esters and negative for FFA) were compared to standards. Protein extracts from human retinal ...
Two principal border tissue configurations, their relationship to a pigmented or unpigmented extension of Bruchs membrane, and the resultant clinical disc margin anatomy. (A) Internally oblique. The diagram shows the clinical optic disc appearance (top) and a cross-section of the optic nerve head (b ottom). Labeling is as follows: 1, sclera; 2, choriocapillaris; 3, retinal pigment epithelium with Bruchs membrane; 4, border tissue; 5, neural canal boundary; 6, pigment on the surface of Bruchs membrane; 7, Bruchs membrane. L eft i nset: pigmented Bruchs membrane corresponds to the halo of pigment on the left side of the disc margin. R ight i nset: region of unpigmented Bruchs membrane is shown; this corresponds to a white crescent internal to the pigment halo at the disc margin, which corresponds to a portion of pigmented Bruchs membrane. (B) Externally oblique. Labeling is according to the schematic in (A). L eft i nset: Bruchs membrane is pigmented to its end and does not extend beyond ...
Richard Bruch is the author of this article in the Journal of Visualized Experiments: Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
Read the Emeryville - Manzanita - Vegan Macrobiotic all-you-can-eat weekend bruch buffet discussion from the Chowhound Restaurants, San Francisco food community. Join the discussion today.
During the lifetime of an internal combustion engine, deposits are formed at various locations. In diesel engines, deposits in the combustion chamber and at the injection nozzles lead to an increase in the emissions, especially the particulate emissions, and the exhaust gas odor. Additionally, durability problems can also arise. Deposits in the combustion chamber of SI engines can increase the octane requirement, deposits at intake valves can reduce engine efficiency and driveability and increase emissions. A detailed theory on the mechanism of deposit formation, considering the physical effects, is presented. This theory contains a deposit transport mechanism, a mechanism of deposit attachment including an induction phase, a deposit growth phase and a deposit removal mechanism. This complex theory is based on fundamental investigations at different locations in and around internal combustion engines. From these investigations, the effects of surface temperature, gas temperature, turbulent gas ...
Definition of ora serrata retinae in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is ora serrata retinae? Meaning of ora serrata retinae as a legal term. What does ora serrata retinae mean in law?
Plantas pequeñas hasta medianas, hasta 3 cm de alto, formando manojos densos, generalmente verde oscuras hasta pardas. Tallos erectos, simples o poco ramificados; cordón central presente o ausente; radiculosos abajo. Hojas escasamente crispas y curvadas o rizadas y contortas en seco, erecto-extendidas hasta patentes en húmedo, oblongo- hasta ligulado-lanceoladas o angostamente lanceoladas hasta lineo-lanceoladas, hasta 4 mm de largo, hasta 0.5 mm de ancho, ápices agudos (y apiculados) o corto-acuminados, bases escasamente envainadoras y ± cóncavas o no; márgenes planos hasta erectos, lisos o undulados, crenulado-papilosos, ocasionalmente dentados abajo; costa simple, fuerte, corto-excurrente, ápices ocasionalmente robustos, en corte transversal bandas de estereidas encima y debajo de las células guía, superficie epidérmica papilosa; células mediales y distales de la lámina subcuadradas, con paredes gruesas, pluripapilosas, papilas sobre el lumen celular de ambas superficies; ...
The Port Angeles city council tonight could formally establish an ad hoc committee to deal with fluoride and the fallout surrounding the councils decision to continue adding it to the water supply.. Last month, the council agreed to form the committee and tasked council members Brad Collins and Sissi Bruch to work with staff on a proposed structure.. Bruch and Collins met last week with city manager Dan McKeen. They determined the goal of the committee was to bridge the divide that exists in the community related to the issue of fluoridation and look for viable alternatives that recognize the importance of oral health in the community.. They also agreed on a proposed list of members with two who are against fluoridation, two for continuing fluoridation, two neutral members and a representatives from the Utility Advisory Committee.. Port Angeles business owner Jake Oppelt and resident Janet Kailin were tabbed as against fluoridation; Dr. Chris Frank and Dr. Alan Peet were cast in the for ...
Plantas pequeñas, delgadas, formando manojos laxos, de color verde oscuro hasta verde-amarillento o pardo-dorado. Tallos erectos, delgados, juláceos, poco ramificados; con cordón central. Hojas amplectantes y profundamente cóncavas, brevemente obloide-obtusas o -truncadas, o abruptamente subuladas desde una base obovada envainadora; márgenes incurvados, enteros o marcadamente erosionado-dentados distalmente; costa simple, subpercurrente o largo excurrente; células de la lámina lisas, células mediales lineales o lineo-vermiculares, con paredes gruesas; células inferiores o basales corto- a largo-rectangulares. Dioicas. Perigonios aparentemente laterales sobre tallos distales, inflorescencias en forma de yemas. Periquecios terminales o de apariencia lateral por innovaciones, hojas mayores y marcadamente convolutas. Setas alargadas, lisas. Cápsulas erectas, urna obloide u ovoide-cilíndrica; opérculo largo-rostrado, oblicuo; gimnostóma o peristoma presente, simple, con 16 dientes, ...
Journal of Clinical and Diagnostic Research aims to publish findings of doctors at grass root level and post graduate students, so that all unique medical experiences are recorded in literature.
Try the bruch formula and one of the Cocotte! An happy evening with friends and its immediately hangover of the day after. So one Saturday morning we were looking for a cozy but quiet, nice and well-stocked place, familiar and cheap. And it is immediately COCOTTE in Milan! All white, looks like a soft cloud similar to the bar of a romantic and lost city of Côte Azur adorned in the walls with decoupage of colorful flowers, hanging bicycles and welcoming… Read More »Cocotte - Milan. ...
Im August 1981 führte IBM den Personalcomputer 5150 ein. Er war eigentlich nicht der erste Personalcomputer, aber er erwies sich als der Personalcomputer schlechthin und revolutionierte nicht nur das Geschäftsleben, sondern auch die Art und Weise, wie die Menschen über die Welt dachten. Der PC des Jahres 1981 stellte einen Bruch gegenüber dem bisherigen Geschäftsmodell von IBM dar, wonach das Unternehmen Computer nicht verkaufte, sondern verleaste. Mit dem 5150 stieg IBM in die Massenproduktion eines standardisierten Gebrauchsgutes ein, bei dem von anderen Unternehmen gefertigte Komponenten zum Einsatz kamen. „Big Blue (wie IBM auch genannt wird) erlaubte es anderen Gesellschaften (namentlich der noch in den Kinderschuhen steckenden Firma Microsoft), seine Software zu entwickeln. Keine gute Tat bleibt unbestraft: Indem es den PC herausbrachte, zerstörte IBM sich als Unternehmen praktisch selbst. Seine Innovation brachte eine enorme Zahl neuer, dynamischer Unternehmen hervor, und um mit ...
Assessment of preoperative topography is important to outcome. ппMICROBIOLOGY HIGH-YIELD PRINCIPLES Page 153 пппппппппппппппппппппппппппппппппппппппппPicornavirus Rhinovirus Rotavirus Paramyxoviruses Mumps virus Measles virus Influenza 28 Genetic shift (pandemic) Genetic drift (epidemic) Treatment Includes Poliovirus, Echovirus, Rhinovirus, Coxsackievirus, HAV. 9 Progredienz des glaukomatoМsen Gesichtsfeldausfalls eines difference between alesse 28 and 21 Auges parazentrale und periphere GesichtsfeldausfaМlle Parazentralkotom a Bjerrum-Skotom (bogenfoМrmiges Skotom um den Fixierpunkt) b RoМnne-Sprung (nasaler Gesichtsfeldein- bruch unter Einbeziehung des blinden Fleckes bei intaktem zentralen Sehen) c zentraler Gesichtsfeldverfall, einzelne parazentrale oder periphere Reste Amaurose (Erblindung) Parazentralskotom oben.
The Colombian conductor leads the London Philharmonic in an evening of Weber, Bruch and Beethoven where classical discipline comes out on top.
This program present a selection of classic works from the LIMA (formerly Montevideo/NIMK) archive. The videos of this program were produced between 1979 and 1988 by five Dutch and international video artists, including works by pioneers of European video art such as Klaus vom Bruch, Reinier Kurpershoek and Ron Sluik. The selection focuses on the aesthetics of video art produced in the 80s, when the practise of remixing or manipulating film and video footage became popular among artists to create new narrative pieces. The program is presented in collaboration with LIMA ...
When structural forms are of weak morphological intensity (5-10m), there exist two difficulities in indentification and outlining of hydrocarbon deposits: complexity in mapping of tectonic elements and a significant effect of lithological and tectonic factors on a possibility of the deposit formation. Complex analysis of geological and geophysical data was performed in the surveyed area for the outlining of oil deposits. The work resulted in identification of Devorian graben-shape troughs (linear structures of tectonic origin weakly defined in the modern structural plan) probably are the shielding elements. seismic record analysis in the pay formation interval bedding enabled to forecast a change in the section, lateral distribution of deposits with improved porosity and permeability propeties.
Labocon Double Beam UV Seen Spectrophotometer LUVSD-200 Series presents the measurement range of a hundred ninety-1100nm at bandwidth of 0.5, 1.0, 2.0, 4.0nm; these systemsprovidethe excessive accuracy, reproducibility and high throughput at every run. Numerical examples are demonstrated and mentioned in details to verify the Quality pp spunbonded nonwoven machine specially adjusted effectivity of the proposed methodology, which might further help characterize the dynamic responses and design work for double-beam buildings. Thus the Rayleigh beam-kind dynamic absorber with Pasternak layer in-between may be applied to suppress the excessive vibrations of corresponding beam methods and be more effective than the double-beam system with a Winkler elastic layer. The previous single beam sort spectrophotometer has a weak point of error occurrence in measuring a pattern, due to the motion of a light source by time lag in measuring the energy of between a reference light and a light-weight from sample. ...
SOLDATOS, K P and Ye, Jianqiao (1995) Axisymmetrical static and dynamic analysis of laminated hollow cylinders composed of monoclinic elastic layers. Journal of Sound and Vibration, 184 (2). pp. 245-259. ISSN 0022-460X. SOLDATOS, K P and Ye, Jianqiao (1995) Stationary thermoelastic analysis of thick cross-ply laminated cylinders and cylindrical panels. Acta Mechanica, 110 (1-4). pp. 1-18. ISSN 0001-5970. Scott, Jason and Bradley, D. A. and Adelson, Ronald and Pengelly, M. and Seward, D. W. (1995) Issues in the development of data flow simulation of construction sites: the pursuit of quality. International Journal of Project Management, 13 (5). pp. 335-339.. Seward, D. W. and Margrave, F. W. and Sommerville, I. and Kotonyam, G. (1995) Safe systems for mobile robots: the safe-SAM project. In: Proceedings of the 3rd safety-critical systems symposium published as directions in safety-critical systems. Springer-Verlag, Brighton, pp. 153-170.. Soldatos, K P and Ye, Jianqiao (1995) On three-dimensional ...
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Choroidal neovascularization describes the growth of new blood vessels that originate from the choroid through a break in the Bruch membrane into the sub-retinal pigment epithelium (sub-RPE) or subretinal space. Choroidal neovascularization (CNV) is a major cause of visual loss.
Transplanted retinal pigment epithelium (RPE) cells hold promise for treatment of age-related macular degeneration (AMD) and Stargardt disease (SD), but it is conceivable that the degenerated host Bruchs membrane (BM) as a natural substrate for RPE might not optimally support transplanted cell survival with correct cellular organization. We fabricated novel ultrathin three-dimensional (3-D) nanofibrous membranes from collagen type I and poly(lactic-co-glycolic acid) (PLGA) by an advanced clinical-grade needle-free electrospinning process. The nanofibrillar 3-D networks closely mimicked the fibrillar architecture of the native inner collagenous layer of human BM. Human RPE cells grown on our nanofibrous membranes bore a striking resemblance to native human RPE. They exhibited a correctly orientated monolayer with a polygonal cell shape and abundant sheet-like microvilli on their apical surfaces. RPE cells built tight junctions and expressed RPE65 protein. Flat 2-D PLGA film and cover glass as ...
Choroidal ruptures are breaks in the choroid, the Bruch membrane, and the retinal pigment epithelium (RPE) that result from blunt ocular trauma (the most common eye injury). Choroidal rupture can be secondary to indirect or direct trauma.
Skin lesions appear during the second decade of life, with a progressive increase in number and severity during adolescence. The disease is clinically heterogeneous, being limited to only one organ in some patients but affecting all three organs in others. The skin lesions consist of yellow papules that may merge to form plaques. They appear mainly in the flexural areas of the neck and elbows, popliteal spaces and umbilical region, and are accompanied by loosening of the skin around the inguinal folds and armpits. Ophthalmological findings include retinal pigment epithelium anomalies, drusen, angioid streaks (fissuring of the Bruch membrane of the retina), and neovascularization and bleeding leading to retinal hemorrhage and, in many patients, loss of visual acuity. Involvement of the macula may lead to patients being declared as legally blind. Cardiovascular manifestations lead to intermittent claudication of the lower and/or upper limbs due to arteriosclerosis of medium-sized arteries with ...
Age-related macular degeneration (AMD) is a leading cause of vision loss in patients ,50 years old. The hallmark of the disease is represented by the accumulation of extracellular material between retinal pigment epithelium and the inner collagenous layer of Bruchs membrane, called drusen. Although identified almost 30 years ago, reticular pseudodrusen (RPD) have been recently recognized as a distinctive phenotype. Unlike drusen, they are located in the subretinal space. RPD are strongly associated with late AMD, especially geographic atrophy, type 2 and 3 choroidal neovascularization, which, in turn, are less common in typical AMD ...
In this paper, we have sought to address a number of the questions outlined above, to review current information pertaining to drusen classification, and to present new data related to drusen structure, composition, pathobiology, and association with AMD.. Natural History of Drusen. Drusen are extracellular deposits that accumulate between the basal lamina of the retinal pigmented epithelium (RPE) and the inner collagenous layer of Bruchs membrane in the human eye. They are typically associated with advancing age and are commonly observed in a variety of chorioretinal pathologies, including age-related macular degeneration (AMD), the leading cause of irreversible blindness in many countries. Although the presence of large, soft, and/or numerous macular drusen has been shown to be a significant risk factor for the development of AMD, precise information about their origin and composition is lacking.. Drusen were named after the German word for node or geode, and were first described by F.C. ...
Transmission of Light to the Young Primate Retina: Possible Implications for the Formation of Lipofuscin. Gaillard, E.R.; Merriam, J.; Zheng, L.; Dillon, J. (2011) Photochem. Photobiol., 87: 18-21.. Compositional Studies of Human RPE Lipofuscin: mechanisms of molecular modifications. Murdaugh, L.S.; Mandal, S.; Dillon, J.; Simon, J.D.; Gaillard, E.R. (2011) J. Mass Spectrom., 46: 90-95.. Compositional Studies of Human RPE Lipofuscin. Murdaugh, L.S.; Avalle, L.B.; Mandal, S.; Dillon, J.; Simon, J.D.; Gaillard, E.R. (2010) J. Mass Spectrom., 45: 1139-1147.. Carborane‐Appended C3‐Symmetrical Extended π‐Systems: Synthesis and Properties. Hosmane, N.; Dash, B.; Satapathy, R.; Gaillard, E.R.; Maguire, J. (2010) J. Am. Chem. Soc., 132: 6578-6587.. Age‐Related Accumulation of 3‐nitrotyrosine and nitro‐A2E in Human Bruchs Membrane. Murdaugh, L.S.; Wang, Z.; Del Priore, L.V.; Dillon, J.; Gaillard, E.R. (2010) Exp. Eye Res., 90: 564-571.. Physical Properties of the Lipid Bilayer Membrane made ...
Fingerprint Dive into the research topics of Transplanted and repopulated retinal pigment epithelial cells on damaged Bruchs membrane in rabbits. Together they form a unique fingerprint. ...
The apparatus includes an elastic layer for supporting a person. A plurality of rows of expandable and retractable tubes are embedded in the elastic layer. A source of compressed air and a control system are provided for sequentially injecting and releasing air into and from a first set of alternate tubes and then into and from a second set of alternate tubes for imparting continuous motion to the elastic layer.
A method for manufacturing a sensing device, such as a bolometer device or other devices. The method includes providing a substrate, e.g., silicon wafer. The method includes forming a first reflection layer overlying the substrate and forming a first electrode layer overlying the substrate. The method includes forming a sacrificial layer overlying a portion of the first reflection layer and a portion of the first electrode layer. The sacrificial layer is patterned using photolithography techniques. The patterned sacrificial layer corresponds to a cavity region. The method also forms a second electrode layer overlying the sacrificial layer and forms an elastic layer overlying the patterned sacrificial layer. The elastic layer encloses the cavity region corresponding to the patterned sacrificial layer. The method releases the sacrificial layer to form an opening in the cavity region.
0184] TABLE 1 Filler Present Region (Longitudinal Direction Present Region (Thickness Evaluation Filler Present Elasticity of Filler of Foamed Elastic Direction of Foamed Elastic Cleaning Charging Roll or Absent Present or Absent Layer) Layer) Peeling Performance Damage Example 1 Present Elasticity Present Entire Surface 0 to 7% (0 to 0.2 mm) A A A Example 2 Present Elasticity Present Entire Surface 0 to 50% (0 to 1.5 mm) A A A Example 3 Present Elasticity Present Both Ends 0 to 7% (0 to 0.2 mm) A A A Example 4 Present Elasticity Present Both Ends 0 to 50% (0 to 1.5 mm) A A A Example 5 Present Elasticity Present Both Ends 0 to 100% (0 to 3.0 mm) A A A Example 6 Present Elasticity Absent Entire Surface 0 to 7% (0 to 0.2 mm) A B B Comparative Absent -- -- -- C C A Example 1 In the present region (thickness direction), for example, 0 to 7% indicates a region from the lower surface of the foamed elastic layer up to 7% of total thickness of the foamed elastic layer. In the present region (thickness ...
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Lal DR, Gadepalli SK, Downard CD, Minneci PC, Knezevich M, Chelius TH, Rapp CT, Billmire D, Bruch S, Carland Burns R, Deans KJ, Fallat ME, Fraser JD, Grabowski J, Hebel F, Helmrath MA, Hirschl RB, Kabre R, Kohler J, Landman MP, Leys CM, Mak GZ, Ostlie DJ, Raque J, Rymeski B, Saito JM, St Peter SD, von Allmen D, Warner BW, Sato TT. Infants with esophageal atresia and right aortic arch: Characteristics and outcomes from the Midwest Pediatric Surgery Consortium. J Pediatr Surg. 2019 Apr; 54(4):688-692 ...
Lal DR Gadepalli SK Downard CD Minneci PC Knezevich M Chelius TH Rapp CT Billmire D Bruch S Carland Burns R Deans KJ Fallat ME Fraser JD Grabowski J Hebel F Helmrath MA Hirschl RB Kabre R Kohler J Landman MP Leys CM Mak GZ Ostlie DJ Raque J Rymeski B Saito JM St Peter SD von Allmen D Warner BW Sato TT Midwest Pediatric Surgery Consortium. Infants with esophageal atresia and right aortic arch: Characteristics and outcomes from the Midwest Pediatric Surgery Consortium. J Pediatr Surg . 2019 Apr;54(4):688-692 ...
Hello, Thanks to a kind soul ive received a copy of this document! Sarah Enw/Name: Sarah Bruch BSc(Hons), MSc(Merit) Teitl/ Title:Rheolwr Gwasanaethau Gwybodaeth Ysbyty Tywysog Philip/Prince Philip Hospital Knowledge Services Manager Llyfyrgell/Library Ysbyty Tywysog Philip/Prince Philip Hospital Dafen Llanelli Sir Gaerfyrddin/Carmarthenshire SA14 8QF Ffon/Tel: 01554 783467 Facs/Fax: 01554 749301 Did you know there is a book club in the Library at PPH on the last Thursday of every month? See our blog at http://princephiliphospitallibrarybookc.blogspot.com/ and get in touch with Library staff if you would like to join. Gwasanaeth Chwilio ar gyfer Llenyddiaeth Os nad ydych yn gallu dod o hyd ir gwybodaeth yr ydych yn chwilio am, beth am ddefnyddior Llyfyrgell? Rydum yn gallu chwilio am unrhyw llenyddiaeth ar gyfer gweithwyr Bwrdd Iechyd Hywel Dda am ddim. Danfonwch e-bost a gofynwch am ymchwiliad llenyddiaeth. Literature Search Service If you cant find the information youre looking for why ...
Penalva, German; Högberg, Liselotte Diaz; Weist, Klaus; Vlahović-Palčevski, Vera; Heuer, Ole; Monnet, Dominique L; Blix, Hege Salvesen; Simonsen, Gunnar Skov; Wilson, Julie; Vandael, Eline; Ivanov, Ivan; Payerl-Pal, Marina; Pedersen, Karoline Skjold Selle; Linask, Elviira; Schweickert, Birgitta; Kontopidou, Flora; Matuz, Maria; Sarvikivi, Emmi; Cavalié, Philippe; Oza, Ajay; Sigmundsdóttir, Guðrún; Fortinguerra, Filomena; Valinteliene, Rolanda; Bruch, Marcel; Zarb, Peter; Natsch, Stephanie; Olczak-Pienkowska, Anna; Iosif, Ionel; Alonso Herreras, Maria Teresa; Wiener, Vendela; Cizman, Milan; Tesar, Tomas; Muller-Pebody, Berit; Catteau, Lucy; Doneva, Stefana; Tambic Andrasevic, Arjana; Maikanti-Charalampous, Panagiota; Zemlicova, Helena; Sönksen, Ute; Ivanova, Marina; Maugat, Sylvie; Jalava, Jari; Noll, Ines; Polemis, Michalis; Vegh, Zsolt; Kristinsson, Karl G.; Burns, Karen; DAncona, Fortunato; Vulane, Kate; Miciuleviciene, Jolanta. ...
When writing software, developers frequently find themselves in a situation where they are absolutely certain that someone else must have faced (and solved!) the same problem before, but they just cannot find that piece of code. This is where the proposed code search feature can help: Based on the context the developer currently is in (e.g., the current method and the available objects), code search will search through the entire workspace and present pieces of code that match the current context. For this proposal to work well, the search engine must be (1) fast and (2) present its results in a condensed snippet form, so that the developer can quickly decide which results are worth a closer look. A prototype of a code search engine has already been developed as a Masters thesis at Technische Universität Darmstadt. This project could either build upon that prototype or, taking into account the lessons learned there, start from scratch. Possible Mentors: Marcel Bruch, Andreas Sewe (contact us ...
Pieretti-Vanmarcke, Rafael; Velmahos, George C.; Nance, Michael L.; Islam, Saleem; Falcone, Richard A. Jr; Wales, Paul W.; Brown, Rebeccah L.; Gaines, Barbara A.; McKenna, Christine; Moore, Forrest O.; Goslar, Pamela W.; Inaba, Kenji; Barmparas, Galinos; Scaife, Eric R.; Metzger, Ryan R.; Brockmeyer, Douglas L.; Upperman, Jeffrey S.; Estrada, Joaquin; Lanning, David A.; Rasmussen, Sara K.; Danielson, Paul D.; Hirsh, Michael P.; Consani, Heitor F. X.; Stylianos, Steven; Pineda, Candace; Norwood, Scott H.; Bruch, Steven W.; Drongowski, Robert; Barraco, Robert D.; Pasquale, Michael D.; Hussain, Farheen; Hirsch, Erwin F.; McNeely, P Daniel; Fallat, Mary E.; Foley, David S.; Iocono, Joseph A.; Bennett, Heather M.; Waxman, Kenneth; Kam, Kelly; Bakhos, Lisa; Petrovick, Laurie; Chang, Yuchiao; Masiakos, Peter T. Less ...
Advances in the Subcritical, Gas-Cooled, Fast Transmutation Reactor Concept. W. M. Stacey, K. A. Boakye, S. K. Brashear, A. C. Bryson, K. A. Burns, E. J. Bruch, S. A. Chandler, O. M. Chen, S. S. Chiu, J.-P. Floyd, C. J. Fong, S. P. Hamilton, P. B. Johnson, S. M. Jones, M. Kato, B. A. MacLaren, R. P. Manger, B. L. Meriwether, C. Mitra, K. R. Riggs, B. H. Shrader, J. C. Schulz, C. M. Sommer, T. S. Sumner, J. S. Wagner, J. B. Weathers, C. P. Wells, F. H. Willis, Z. W. Friis, J. I. Marquez-Danian, R. W. Johnson, C. de Oliveira, H. K. Park, D. W. Tedder. ...
Posted by Fossil on October 20, 2004 at 06:29:06:. We are currently operating a B&W El Paso style RB boiler fired on number 6 fuel oil as a peaking unit. The water chemistry on the unit is ok, but as you can imagine is cyclic due to the boiler cycling. We have had a continuous problem of hydrogen damage in the lower hopper slope, in which we have completed in kind replacements (SA-210 A1). The angle of the lower slope is very low, which is susceptible to deposit formation. Has any tried upgrading material to T-11 (or similar) to help prolong the life of their water wall tubing due to hydrogen damage? EPRI lists this to help minimize hydrgoen damage ...
Usually, pseudoxanthoma elasticum affects the skin first, often in childhood but frequently later. Small, yellowish papular lesions form and cutaneous laxity mainly affects the neck, axillae (armpits), groin, and flexural creases (the inside parts of the elbows and knees). Skin may become lax and redundant. Many individuals have oblique mental creases (diagonal grooves of the chin).[2]. PXE first affects the retina through a dimpling of the Bruch membrane (a thin membrane separating the blood vessel-rich layer from the pigmented layer of the retina), that is only visible during ophthalmologic examinations. This is called peau dorange (a French term meaning that the retina resembles the skin of an orange). Eventually the mineralization of the elastic fibers in the Bruch membrane create cracks (angioid streaks) that radiate out from the optic nerve. Angioid streaks themselves do not cause distortion of vision, even if they cross into the foveal area. This symptom is present in almost all PXE ...
Pseudoxanthoma elasticum is a hereditary connective tissue disease related to a mutation in the ABCC6 gene located on chromosome 16p13.1, that encodes the multidrug resistance protein 6 (MRP6), which is one of the family of adenosine triphosphate-dependent membrane transport proteins, which are mostly expressed in the liver and kidneys. Two types of inheritance have been described: autosomal recessive in 90% of the cases and autosomal dominant, much rarer. Mutation in the ABCC6 gene provokes an absence of MRP6, which leads to an accumulation of substances with a high affinity for elastic tissues, resulting in the distortion of calcium deposits and fragmentation of elastic fibers.. Cutaneous manifestations include asymptomatic yellowish papules distributed symmetrically from the start of the neck that can extend to the flexure area. Although not pathognomonic, a characteristic ocular finding is the presence of angioid streaks that represent calcium deposits on the Bruch membrane. They can cause ...
The Starved Self from the February 22, 1979 issue To the Editors:. I am writing to you on suggestion of Mr. Arthur Rosenthal (Harvard University Press) with whom I discussed my concern about the review of my book The Golden Cage: The Enigma of Anorexia Nervosa (together with three other books) in the February 22, 1979 issue of The New York Review of Books.. Let me first express my satisfaction that this topic was reviewed in such a prominent way. This tragic illness befalls the daughters of intellectual and sophisticated families, such as the readership of the Review, in ever-increasing numbers. It is therefore important that they receive accurate information about this illness.. The review was done by Rosemary Dinnage. She gives a vivid and on the whole accurate description of the clinical picture of anorexia nervosa, with several quotations from The Golden Cage and also from my earlier book, Eating Disorders. She points out correctly that Selvini, the author of Self-Starvation, and I hold ...
In VKH disease, detection of choroiditis is still a challenge. Thus, newer parameters to detect posterior segment inflammation and to assist the treatment process are needed. Herein, we describe the choroidal bulging, a transient finding identified on EDI-OCT in patients with VKH disease in the non-acute uveitic stage. The choroidal bulging is characterized by a localized thickening of the choroidal compartment with consequent bulging of the RPE/Bruch reflective complex anteriorly, without an associated retinal thickening or any obvious nearby retinal lesion to justify this finding. Signs of well-known ongoing disease-related inflammation/activity were concomitantly observed in all four eyes presenting choroidal bulging, and fluctuation of this inflammatory signs was followed by changes in the choroidal bulging.. Diffuse thickening of the choroid has already been described in the early and convalescent/chronic stages of VKH [3, 4], and it was suggested to represent a sign of disease activity [3, ...
Obtaining tribal back tattoo is an effective idea UGG Boots Sale, but as you fully understand prada shoes sale, there are many things you need to think about before getting the new ink. Artwork tory bruch outlet, what tattoo parlor UGG Boots, health concerns UGG Sale, all of these are a natural part of your decision. You are about to drop adequate your hard-earned cash on this new tattoo so please take some time because it can make the difference between a fantastic tattoo and a basically OK tattoo. One of the hugest mistakes you can also make when researching your cutting edge ink is heading onto Google Images. Google Images has some great ideas canada goose, but these pieces of artwork have been completely on someones body in order that you run the risk for duplicating art. And I have feeling youd like to have something unique jerseys wholesale, right? One of the best decisions that you could make is to invest in a pay tattoo site. The benefits that these sites offer are perfect. One of the ...
Obtaining tribal back tattoo is an effective idea UGG Boots Sale, but as you fully understand prada shoes sale, there are many things you need to think about before getting the new ink. Artwork tory bruch outlet, what tattoo parlor UGG Boots, health concerns UGG Sale, all of these are a natural part of your decision. You are about to drop adequate your hard-earned cash on this new tattoo so please take some time because it can make the difference between a fantastic tattoo and a basically OK tattoo. One of the hugest mistakes you can also make when researching your cutting edge ink is heading onto Google Images. Google Images has some great ideas canada goose, but these pieces of artwork have been completely on someones body in order that you run the risk for duplicating art. And I have feeling youd like to have something unique jerseys wholesale, right? One of the best decisions that you could make is to invest in a pay tattoo site. The benefits that these sites offer are perfect. One of the ...
In the study of [Improvement in the healing of colonic anastomoses by vitamin B5 and C supplements. Experimental study in the rabbit] [Article in French], by Vaxman F, Chalkiadakis G, Olender S, Maldonado H, Aprahamian M, Bruch JF, Wittmann T, Volkmar P, Grenier JF., posted in US National Library of Medicine National Institutes of Health, researchers found that Vitamins B5 and C enhance the colonic wound healing process in the rabbit, acting together in synergy in vivo as well as in vitro, as previously demonstrated ...
Lal DR, Gadepalli SK, Downard CD, Ostlie DJ, Minneci PC, Swedler RM, Chelius TH, Cassidy L, Rapp CT, Billmire D, Bruch S, Burns RC, Deans KJ, Fallat ME, Fraser JD, Grabowski J, Hebel F, Helmrath MA, Hirschl RB, Kabre R, Kohler J, Landman MP, Leys CM, Mak GZ, Raque J, Rymeski B, Saito JM, St Peter SD, von Allmen D, Warner BW, Sato TT. Challenging surgical dogma in the management of proximal esophageal atresia with distal tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium. J Pediatr Surg. 2018 Jul; 53(7):1267-1272 ...
Englum, B. R., Rothman, J., Leonard, S., Reiter, A., Thornburg, C., Brindle, M., Wright, N., Heeney, M. M., Jason Smithers, C., Brown, R. L., Kalfa, T., Langer, J. C., Cada, M., Oldham, K. T., Scott, J. P., Peter, S. D. S., Sharma, M., Davidoff, A. M., Nottage, K., Bernabe, K. & 15 others, Wilson, D. B., Dutta, S., Glader, B., Crary, S. E., Dassinger, M. S., Dunbar, L., Islam, S., Kumar, M., Rescorla, F., Bruch, S., Campbell, A., Austin, M., Sidonio, R., Blakely, M. L. & Rice, H. E., Jan 1 2016, In : Journal of pediatric surgery. 51, 1, p. 122-127 6 p.. Research output: Contribution to journal › Article ...
The LDL receptor knockout model serves as an established model for atherosclerotic pathomechanisms because of the opportunity to induce elevated pTC levels.. In our study pTC was significantly increased by LDL receptor deficiency as well as HF diet. LDL receptor deficient mice after HF diet showed the highest average pTC, which was 6.0 times more than in C57Bl/6J control mice consuming standard chow diet.. Furthermore, we demonstrated a structural degeneration of BrM with thickening and accumulation of membrane and non-membrane bound translucent particles in LDL receptor deficient mice correlating with significantly elevated pTC levels. The layer arrangement was affected as well. These degenerations were most prominent in LDL receptor deficient mice after HF diet. Hypercholesterolaemia as an atherosclerotic risk factor seems to predispose to these structural alterations in BrM.. The observed changes in murine BrM resemble those seen in human eyes of aged donors and donors with ARM.11-13 Electron ...
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Drusen in the retina is a common finding in aging retina, forming deposits in the retina between Bruchs membrane and the retinal pigment epithelium. Most people over 40 start to accumulate some drusen, but increasing amounts of drusen formation can indicate pathological developments associated with age related macular degeneration, (AMD). Cristine Curcio has been chasing […]. ...
Particulates end up being caught on filter surfaces, storage tank wall surfaces, as well as fuel lines. The outcome is a minimized fuel filter life, dirty fuel storage tanks, clogged lines, as well as connected displays. Just recently, numerous fleets have viewed gas filters connected with black goo, which can be induced by the particulates, which are usually the outcome of thermally unsteady fuel. The gas filter could not catch better particulates that may trigger fuel system wear, plunger damage, boosted deposit formation and also premature fuel pump wear. The Diesel fuel polishing services website website addresses all of these issues and more. For even more information;. Surfactants. Surfactants are materials that decrease the surface strain of fuel/water and consequently promote fuel/water emulsions. The surface-active substances originate from different sources, including refinery therapy chemicals, naturally taking place products not gotten rid of from the petroleum, selected from other ...
Castrol Tection DD Monograde 40 is a high performance trunk piston diesel engine lubricant, especially formulated to meet the latest performance requirements for General Motors Detroit Diesel 2-stroke engines operating with distillate fuels of up to 0.5% sulphur content. Castrol Tection DD Monograde 40 is a blend of high quality paraffinic base oils inhibited against oxidation and corrosion and combined with detergent, dispersant and anti-wear additives. This combination ensures minimum deposit formation on pistons, combustion chambers and exhaust valves, reduces mechanical and corrosive wear and provides protection against high and low temperature sludge formation, oxidation and rusting. Castrol Tection DD Monograde 40 conforms to the API CF-2 performance specification. The low ash additive technology utilised in the formulation of Castrol DD 40 comfortably meets the Detroit Diesel level of 0.8% maximum required for the 149 series engine.. ...
The need for improved emissions control in lean exhaust to meet tightening, world-wide NOx emissions standards has led to the development of selective catalytic reduction of NOx with ammonia as a major technology for emissions control. Current systems are being designed to use a solution of urea (32.5 wt %) dissolved in water or Diesel Exhaust Fluid (DEF) as the ammonia source. While DEF or AdBlue® is widely used as a source of ammonia, it has a number of issues at low temperatures, including freezing below −12 °C, solid deposit formation in the exhaust, and difficulties in dosing at exhaust temperatures below 200 °C. Additionally creating a uniform ammonia concentration can be problematic, complicating exhaust packaging and usually requiring a discrete mixer ...
A method for electrically connecting a thin film electrode to a connecting terminal on an active matrix in the manufacture of a thin film actuated mirror is disclosed. The method includes the steps of: forming a thin film sacrificial layer having an empty cavity on top of the active matrix; forming an elastic, a second thin film and a thin film electrodisplacive layers, successively, on top of the thin film sacrificial layer including the empty cavity; forming a contact hole extending from top of the thin film electrodisplacive layer to top of the connecting terminal; forming a first thin film layer on top of the thin film electrodisplacive layer including the contact hole; patterning the first thin film, the thin film electrodisplacive, the second thin film and the elastic layers, respectively; and removing the thin film sacrificial layer, thereby forming the thin film actuated mirror.
Perhaps these findings mean. The physician should watch for signs of trauma, an emergent operative delivery, which will resolve completely by age in weeks. Preganglionic sympathetic innervation of the patient. The methodology was abstracted from a kerion of the trauma patient, part ii a ii b figure. For this reason, somatic dysfunction enhances and supports high-fidelity representation of the hand to flex the shoulder girdle motion, observe the coronal plane, approximately to of exposures are benign in nature, a multidisciplinary approach that assesses the triad are present in patients with appropriate dosing. Specically, creatinine does not match the facets of the patients input and consensus. World j surg , randolph gr, hagler dj, khandheria bk, et al direct versus indirect signs of suffering, such as chest pain must be provided by five different nerve supplies the index nger make an o with the elastic layers present in a minority of cases. The incidence of somatic dysfunction offer orthopedic ...
VP: We tend to look at law like medicine, in the way of the applicability of taxonomies, etiologies, and cures, though the latter is far more singular in the law. That is to say, law is only (may only be) proscriptive, not pre-. As negation is its base, negation is its remedy. Negation of time in a sentence, negation of life in a capital (US) offense. Long sentences being death, as Ive said before, on the installment plan. That said, like medicine, or, for that matter, like any narration, or meta-narrative, law is a louche beast. The entire job of the law (as noted) is to stuff ooze into prefabricated forms, to take unwieldy facts and act as if they are, like fiction, calculable, disposable in the sense of consumed by its functional use. The weak link is the case that exposes the inutility of the legal process qua processing plant, where ontology meets the dérive. I.e., that this disposability is not a question of utility or perfect consumption (facts in, law out) but rather of immateriality, ...
It is characterized by a breakdown of the RPE/Bruch's membrane complex in the retina, leading to an accumulation of cholesterol ... Measurement of a patient's dark adaptation function is essentially a bioassay of the health of their Bruch's membrane. As such ... Curcio, CA (2013). Structure, function, and pathology of Bruch's membrane. In: Ryan SJ, et al, eds. Retina, Vol 1, Part 2: ... the RPE/Bruch's function continues to deteriorate, hampering nutrient and oxygen transport to the rod and cone photoreceptors. ...
R Guymer, P Luthert, A Bird (1999) Changes in Bruch's membrane and related structures with age. Progress in retinal and eye ... Guymer, R.; Luthert, P.; Bird, A. (1999). "Changes in Bruch's membrane and related structures with age". Progress in Retinal ...
Henle's membrane: Bruch's layer forming inner boundary of the choroid of the eye. Henle's sheath: Connective tissue which ... Hassall-Henle bodies: Transparent growths in the periphery of the Descemet membrane of the eye. Henle's fissure: Fibrous tissue ... serous membranes, kidney, eye, nails, central nervous system, etc. He discovered the loop of Henle and Henle's tubules, two ...
... and Bruch's membrane (synonyms: Lamina basalis, Complexus basalis, Lamina vitra) - innermost layer of the choroid. There are ...
CNV can occur rapidly in individuals with defects in Bruch's membrane, the innermost layer of the choroid. It is also ...
It is situated between the Bruch's membrane, choriocapillaris and Haller's layer below, and the suprachoroidea above, ...
The lesion may occur within the choroid, between Bruch's membrane and RPE, or between the RPE and photoreceptors. Despite the ...
"Carbon nanotube bucky paper as an artificial support membrane and Bruch's membrane patch in subretinal RPE and IPE ...
... also called Knapp streaks or Knapp striae are small breaks in Bruch's membrane, an elastic tissue containing membrane of the ... From histopathological research in the 1930s, they were discovered to be caused by changes at the level of Bruch's membrane. ... Presently, it is believed that its pathology may be a combination of elastic degeneration of Bruch's membrane, iron deposition ...
Dry (non-exudative, > 80%)-deposition of yellowish extracellular material in and between Bruch's membrane and retinal pigment ... For people who have conditions such as Epiretinal membrane (ERM), Macular Holes and Retinal Detachment, decreased ... Some of these conditions include the following: Age-related macular degeneration Epiretinal membrane and vitreomacular traction ...
... are not related to Bruch membrane drusen of the retina which have been associated with age-related macular ... Rarely choroidal neovascular membranes may develop adjacent to the optic disc threatening bleeding and retinal scarring. Laser ... Chaudhry NA, Lavaque AJ, Shah A, Liggett PE (2005). "Photodynamic therapy for choroidal neovascular membrane secondary to optic ... Central vision loss is a rare complication of bleeding from peripapillar choroidal neovascular membranes. Anterior ischemic ...
The inherited disorder pseudoxanthoma elasticum may lead to angioid streaks with calcification of Bruch's membrane, the elastic ... occurring in areas of cell necrosis when activated phosphatases bind calcium ions to phospholipids in the membrane. Caseous ...
The capillary lamina of choroid or choriocapillaris is a layer of capillaries that is immediately adjacent to Bruch's membrane ... The cell membrane is reduced to a single layer at the fenestrations, facilitating the movement of material through the vessel ...
In 1899 Doyne discovered colloid bodies lying on Bruch's membrane that appeared to merge, forming a mosaic pattern that ... a disorder that affects Bruch's membrane, the innermost layer of the choroid. Two years after his death in 1916, a prized ...
If further damage to Bruch's membrane and the pigment epithelium causes fluid to accumulate under the retina, central serous ... and a continuous leakage of fluid in the direction of the adjacent Bruch's membrane and retinal pigment epithelium, the ...
In many cases, people with MPGN II can develop drusen caused by deposits within Bruch's membrane beneath the retinal pigment ... It should not be confused with membranous glomerulonephritis, a condition in which the basement membrane is thickened, but the ... Over time, vision can deteriorate, and subretinal neovascular membranes, macular detachment, and central serous retinopathy can ... is a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (GBM) thickening, ...
... are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment ... "An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface ...
Examples include the skin of the breast in inflammatory breast cancer, in the eye due to breaks in Bruch's Membrane called ...
Bruch's membrane (lamina basalis choroideae) This disambiguation page lists articles associated with the title Lamina basalis. ...
... bruch membrane MeSH A09.371.894.280 - ciliary body MeSH A09.371.894.513 - iris MeSH A09.371.894.513.780 - pupil MeSH A09.531. ... bowman membrane MeSH A09.371.060.217.228 - corneal stroma MeSH A09.371.060.217.271 - descemet membrane MeSH A09.371.060.217.318 ... MeSH A09.246.272.396 - ear canal MeSH A09.246.272.405 - ear cartilages MeSH A09.246.272.702 - tympanic membrane MeSH A09.246. ... tectorial membrane MeSH A09.246.631.246.577 - organ of corti MeSH A09.246.631.246.577.325 - hair cells MeSH A09.246.631.246. ...
... basement membrane MeSH A10.615.179.124 - basilar membrane MeSH A10.615.179.250 - bruch membrane MeSH A10.615.179.437 - descemet ... basement membrane MeSH A10.272.220.250 - bruch membrane MeSH A10.272.491 - endothelium MeSH A10.272.491.318 - endothelium, ... membrane MeSH A10.615.179.625 - glomerular basement membrane MeSH A10.615.284 - extraembryonic membranes MeSH A10.615.284.147 ... mucous membrane MeSH A10.615.550.291 - gastric mucosa MeSH A10.615.550.291.150 - chief cells, gastric MeSH A10.615.550.291.162 ...
Bruch's membrane Drusen Fovea centralis Fundus (eye) Macula of retina This article incorporates text in the public domain from ... Phagocytosis of photoreceptor outer segment (POS) membranes: POS are exposed to constant photo-oxidative stress, and they go ...
... which is across the retinal pigment epithelium and Bruch's membrane. The high spatial density of cones along with the absence ...
Examples of basement membranes include: Basilar membrane Bruch's membrane Descemet's membrane Glomerular basement membrane The ... The basement membrane is visible under light microscopy. Electron microscopy shows that the basement membrane consists of three ... It is often incorrectly referred to as the basement membrane, though it does constitute a portion of the basement membrane. The ... Alveolar-capillary barrier Basolateral membrane Collagen Glomerular basement membrane Lamina propria Reticular lamina Histology ...
... and Lom u Mostu in the Czech Republic Bruch's membrane, the innermost layer of the choroid in the eye 5004 Bruch, an asteroid ... Bruch may refer to the following Bruch, Lot-et-Garonne, a commune in the Lot-et-Garonne département, France Bruch, Rhineland- ... German ornithologist Carlos Bruch born Franz Karl Bruch (1869-1943), German-born Argentinian entomologist Ernst Brüche (1900- ... German composer Ricky Bruch (1946-2011), Swedish athlete Volker Bruch (born 1980), German actor Walter Bruch (1908-1990), ...
... thickening and breaks in Bruch's membrane. Bruch's membrane was named after the German anatomist Karl Wilhelm Ludwig Bruch. Lee ... Bruch's membrane is present by midterm in fetal development as an elastic sheet. Bruch's membrane thickens with age, slowing ... Bruch's membrane is the innermost layer of the choroid. It is also called the vitreous lamina or Membrane vitriae, because of ... Bruch's membrane consists of five layers (from inside to outside): the basement membrane of the retinal pigment epithelium the ...
"Bruch's membrane": Innermost layer of the choroid. Bibliotheca zoologica Verzeichnis der Schriften über Zoologie ..., Volume 1 ... Karl Wilhelm Ludwig Bruch (May 1, 1819 - January 4, 1884) was a German anatomist born in Mainz. In 1842 he earned his medical ... "). "Bruch's glands": Lymph nodes located in the palpebral conjunctiva. Sometimes referred to as trachoma glands. " ...
PXE first affects the retina through a dimpling of the Bruch membrane (a thin membrane separating the blood vessel-rich layer ... These cracks may allow small blood vessels that were originally held back by Bruch's membrane to penetrate the retina. These ... Bruch's membrane and the midsized arteries.[12] Recent studies hypothesize that PXE is a metabolic disease, and that its ... Eventually the mineralization of the elastic fibers in the Bruch membrane create cracks (angioid streaks) that radiate out from ...
Bruch's membrane. *Sattler's layer. Ciliary body. *Ciliary processes. *Ciliary muscle. *Pars plicata ...
RPE mitochondria zone + Junction between the RPE & Bruch's membrane Very Hyper-reflective ... Inner limiting membrane - basement membrane elaborated by Müller cells.. *Nerve fibre layer - axons of the ganglion cell bodies ... Internal limiting membrane (ILM). Formed by Müller cell endfeet (unclear if it can be observed on OCT) ... RPE/Bruch's complex RPE phagosome zone Very Hyper-reflective No [22][23] ...
Treister NS, Bruch JM (2010). Clinical oral medicine and pathology. New York: Humana Press. pp. 19, 21, 92, 93. ISBN 978-1- ... That is, oral candidiasis is a mycosis (yeast/fungal infection) of Candida species on the mucous membranes of the mouth. ... It may precede the formation of a pseudomembrane, be left when the membrane is removed, or arise without prior pseudomembranes ... the organisms must be capable of adhering to the epithelial surface of the mucous membrane lining the mouth. This adhesion ...
Treister NS, Bruch JM (2010). Clinical oral medicine and pathology. New York: Humana Press. pp. 59-62. ISBN 978-1-60327-519-4. ... Lichen planus is a chronic inflammatory and immune mediated disease that affects the skin, nails, hair, and mucous membranes.[1 ... Mucous membrane pemphigoid and other autoimmune blistering diseases may present with oral erosions and desquamative gingivitis ... upregulation of matrix metalloproteinases that disrupt the epithelial basement membrane zone and allow entry of immune cells ...
Treister JM, Bruch NS (2010). Clinical oral medicine and pathology. New York: Humana Press. pp. 53-56. ISBN 978-1-60327-519-4. ... which develop into ulcers that are covered with a yellow-grey fibrinous membrane that can be scraped away. A reddish "halo" ... Bruch JM, Treister N (2009). Clinical Oral Medicine and Pathology. Springer Science & Business Media. p. 53. ISBN 9781603275200 ... Early lesions have a central zone of ulceration covered by a fibrinous membrane. In the connective tissue deep to the ulcer ...
... a membrane potential. The three primary types of photoreceptors are: Cones are photoreceptors which respond significantly to ...
Bruch's membrane. *Sattler's layer. Ciliary body. *Ciliary processes. *Ciliary muscle. *Pars plicata ...
Bruch's membrane. *Sattler's layer. Ciliary body. *Ciliary processes. *Ciliary muscle. *Pars plicata ...
Bruch's membrane. *Sattler's layer. Ciliary body. *Ciliary processes. *Ciliary muscle. *Pars plicata ...
Bruch's membrane. *Sattler's layer. Ciliary body. *Ciliary processes. *Ciliary muscle. *Pars plicata ...
布鲁赫膜(英语:Bruch's membrane). *Sattler's layer(英语:Sattler's layer) ...
Bruch's membrane. *Sattler's layer. Ciliary body. *Ciliary processes. *Ciliary muscle. *Pars plicata ...
Treister NS, Bruch JM (2010). Clinical oral medicine and pathology. New York: Humana Press. pp. 92-93, 144. ISBN 978-1-60327- ... Vitamin B2 deficiency (ariboflavinosis) may also cause AC, and other conditions such as redness of mucous membranes, magenta ...
It is a clear, membrane-like structure that is quite elastic, a quality that keeps it under constant tension. As a result, the ...
Treister, Jean M. Bruch, Nathaniel S. (2010). Clinical oral medicine and pathology. New York: Humana Press. pp. 137-138. ISBN ... "burning pain in the tongue or other oral mucous membranes",[7] and the International Headache Society defines it as "an intra- ...
Bruch's membrane. *Sattler's layer. جسم مژگانی. *Ciliary processes. *ماهیچه مژگانی. *Pars plicata ...
The inherited disorder pseudoxanthoma elasticum may lead to angioid streaks with calcification of Bruch's membrane, the elastic ... It occurs in areas of cell necrosis in which activated phosphatases bind calcium ions to phospholipids in the membrane. ...
Bruch's membrane. *Sattler's layer. Ciliary body. *Ciliary processes. *Ciliary muscle. *Pars plicata ...
Mucous membrane pemphigoid and other autoimmune blistering diseases may present with oral erosions and desquamative gingivitis ... ISBN 978-1-4051-6911-0. Treister NS, Bruch JM (2010). Clinical oral medicine and pathology. New York: Humana Press. pp. 59-62. ... and mucous membranes. It is not an actual lichen, and is only named that because it looks like one. It is characterized by ... An amorphous band of eosinophilic material at the basement membrane composed of fibrin or fibrinogen. A lichenoid (band-like) ...
Brüche made a sketch of his photoelectron emission microscope in his 1933 paper (Figure 1). This is evidently the first ... In such a configuration, the vacuum side of the second membrane was coated with the photoemitting material and PEEM was used to ... Brüche, E. (1933-07-01). "Elektronenmikroskopische Abbildung mit lichtelektrischen Elektronen". Zeitschrift für Physik (in ... True PEEM imaging of liquid interfaces in photoelectrons has been realized through ultrathin electron transparent membranes ...
Dincer C, Bruch R, Kling A, Dittrich PS, Urban GA (August 2017). "Multiplexed Point-of-Care Testing - xPOCT". Trends in ... Many point-of-care test systems are realized as easy-to-use membrane-based test strips, often enclosed by a plastic test ... has been reported which employs free-standing enzyme-modified responsive polymer membrane-based biosensors and a newly devised ...
ISBN 978-81-7482-180-5. Dincer, Can; Bruch, Richard; Costa‐Rama, Estefanía; Fernández‐Abedul, Maria Teresa; Merkoçi, Arben; ... and where the metal gate is replaced by an ion-sensitive membrane, electrolyte solution and reference electrode. The ISFET is ... such as a dialysis membrane or a hydrogel, or a 3D polymer matrix, which either physically constrains the sensing macromolecule ...
... thickening and breaks in Bruchs membrane. Bruchs membrane was named after the German anatomist Karl Wilhelm Ludwig Bruch. Lee ... Bruchs membrane is present by midterm in fetal development as an elastic sheet. Bruchs membrane thickens with age, slowing ... Bruchs membrane is the innermost layer of the choroid. It is also called the vitreous lamina or Membrane vitriae, because of ... Bruchs membrane consists of five layers (from inside to outside): the basement membrane of the retinal pigment epithelium the ...
The Bruchs membrane is the blood-retina barrier that separates the RPE cells of the retina from the choroid. This membrane is ... The Bruchs membrane is the blood-retina barrier that separates the RPE cells of the retina from the choroid. This membrane is ... Bruchs membrane. The blood-retina barrier that separates the retina from the rest of the body, that is often broken in ...
Bruchs Membrane. Bruchs membrane is a highly specialized and multi-laminar structure in our retinas that forms the basis for ... this image from mouse would be a good addition showing the relationship of the basal surface of the RPE with Bruchs membrane. ... Tag: Bruchs membrane. Posted on September 5, 2015. January 3, 2016. ...
... bruch membrane include Culturing of Retinal Pigment Epithelial Cells on an Ex Vivo Model of Aged Human Bruchs Membrane. ... It is a membrane composed of the basement membranes of the choriocapillaris Endothelium and that of the Rpe. The membrane stops ... Culturing of Retinal Pigment Epithelial Cells on an Ex Vivo Model of Aged Human Bruchs Membrane. Hui Cai1, Jie Gong1, Lucian V ... Bruch Membrane: The inner layer of Choroid, also called the lamina basalis choroideae, located adjacent to the Retinal pigment ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
Semi-automated 2D Bruchs membrane shape analysis in papilledema using spectral-domain optical coherence tomography Author(s): ... In the approach, after the manual placement of the two Bruchs membrane opening (BMO) points, the remaining 18 landmarks are ... Recent studies have shown that the Bruchs membrane (BM) and retinal pigment epithelium (RPE), visualized on spectral-domain ...
Mice With Cholesterol in Bruchs Membrane: Have We Arrived? You will receive an email whenever this article is corrected, ... Christine A. Curcio; Mice With Cholesterol in Bruchs Membrane: Have We Arrived?. Invest. Ophthalmol. Vis. Sci. 2014;55(11): ... Rudolf M Mohi A Dettbarn MC Detection of esterified cholesterol in murine Bruchs membrane wholemounts with a perfringolysin O- ... features a marked lipidization of human Bruchs membrane (BrM). Both phenomena are attributed to esterified cholesterol (EC)- ...
Purpose.: To determine the effect of Stokes radius (R S) on the diffusion of molecules through Bruchs membrane (BM), and to ... The Relationship Between Bruchs Membrane Opening-Minimum Rim Width and Retinal Nerve Fiber Layer Thickness and a New Index ... Huang JD Presley JB Chimento MF Curcio CA Johnson M . Age-related changes in human macular Bruchs membrane as seen by quick- ... Marshall J Hussain AA Starita C Moore DJ Patmore AL . Aging and Bruchs membrane. In: Marmor MF Wolfensberger eds. The Retinal ...
Some patients with age-related changes at the level of Bruchs membrane and good visual acuity report poor vision in dim light ... Symptomatic abnormalities of dark adaptation in patients with age-related Bruchs membrane change. ... Symptomatic abnormalities of dark adaptation in patients with age-related Bruchs membrane change. ... abnormality of both scotopic sensitivity and the time course of dark adaptation in patients with age-related Bruchs membrane ...
Utility of Bruch membrane opening-based optic nerve head parameters in myopic subjects *article ... With GPME, we analyzed the neuroretinal rim (Bruch membrane opening-minimum rim width [BMO-MRW]) and RNFL. ...
Bruchs membrane explanation free. What is Bruchs membrane? Meaning of Bruchs membrane medical term. What does Bruchs ... Looking for online definition of Bruchs membrane in the Medical Dictionary? ... Bruchs membrane. Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.. Related to Bruchs membrane: Drusen, ... However, in eyes where the RPE has separated from Bruchs membrane (as in PED due to AMD or CSR), Bruchs membrane appears as a ...
Bruchs membrane breakage with a choroidal neovascular membrane, subretinal fluid and retinal hemorrhage in wet AMD. , Download ... Bruchs membrane breakage with a choroidal neovascular membrane, subretinal fluid and retinal hemorrhage in wet AMD. ...
Bruch, Karl explanation free. What is Bruch, Karl? Meaning of Bruch, Karl medical term. What does Bruch, Karl mean? ... Looking for online definition of Bruch, Karl in the Medical Dictionary? ... Bruch membrane. A glassy membrane of the uvea of the eye, lying between the choroid membrane and the pigmented epithelium of ... Bruch, Karl. Bruch, Karl. (brook, brookh) Karl Wilhelm Ludwig Bruch, Ger. anatomist, 1819-1884. ...
bruchs membrane - ˈbru̇]ks , ü], ]ḵs noun Usage: usually capitalized B Etymology: after Carl W. L. Bruch died 1884 German ... Bruch glands layer (membrane) - (brook) [Karl Wilhelm Ludwig Bruch, German anatomist, 1819â€"1884] see under gland, and see ... Bruch - Bruch, the German word for fraction , may refer to the following* Bruch, Lot et Garonne, a commune in the Lot et ... Bruchs membrane - the transparent innermost layer of the choroid, which is in contact with the retinal pigment epithelium (see ...
Journal of Clinical and Diagnostic Research aims to publish findings of doctors at grass root level and post graduate students, so that all unique medical experiences are recorded in literature.
Curcio, C. A., Johnson, M., Rudolf, M., & Huang, J. D. (2011). The oil spill in ageing Bruch membrane. British Journal of ... Curcio, CA, Johnson, M, Rudolf, M & Huang, JD 2011, The oil spill in ageing Bruch membrane, British Journal of Ophthalmology ... The oil spill in ageing Bruch membrane. / Curcio, Christine A.; Johnson, Mark; Rudolf, Martin; Huang, Jiahn Dar. ... Oil red O binding neutral lipid represents a major age-related deposition in the Bruch membrane (BrM) and the first identified ...
RESULTS The rupture rate of Bruchs membrane was 0% at 0.5 W, 5% at 1.0 W, 20% at 1.5 W, 70% at 2.0 W, and 100% for all powers ... The aim of this study was to determine the lowest argon laser power at which Bruchs membrane and the retinal vein are ruptured ... CONCLUSION Argon green laser powers of at least 2.5 and 3.0 W were necessary to rupture Bruchs membrane and the retinal vein, ... Light microscopy was used to determine the frequency of rupture of Bruchs membrane and the retinal vein for each power. ...
We observe reduced expression of major components of Bruchs membrane in the eyes of two BCS patients with a PRDM5 Δ9-14 ... particularly the extracellular matrix composition of Bruchs membrane. Immunohistochemistry using antibodies against PRDM5, ... Bruchs membrane abnormalities in PRDM5-related brittle cornea syndrome. Access & Citations. * 2040 Article Accesses. ...
"Bruchs membrane": Innermost layer of the choroid. Bibliotheca zoologica Verzeichnis der Schriften über Zoologie ..., Volume 1 ... Karl Wilhelm Ludwig Bruch (May 1, 1819 - January 4, 1884) was a German anatomist born in Mainz. In 1842 he earned his medical ... "). "Bruchs glands": Lymph nodes located in the palpebral conjunctiva. Sometimes referred to as trachoma glands. " ...
Bereczki, A. ; Toth, J. ; Süveges, I. / Histological examination of the pigment epithelium-Bruch membrane-choriocapillaris ... Bereczki, A., Toth, J., & Süveges, I. (2000). Histological examination of the pigment epithelium-Bruch membrane- ... Bereczki, A, Toth, J & Süveges, I 2000, Histological examination of the pigment epithelium-Bruch membrane-choriocapillaris ... Histological examination of the pigment epithelium-Bruch membrane-choriocapillaris complex after macular translocation. British ...
... including the retinal pigment epithelium and the Bruchs membrane. Find out what happens in an eye with AMD. ... Think of the Bruchs membrane as the store as well as the garbage transfer station. The healthy RPEs go to the Bruchs membrane ... What does the Bruchs membrane do?. Drusen create a nasty working environment for the cells in your eye but this is not all ... Now imagine there is a big pile of eye poop that has gotten between the RPEs and the Bruchs membrane. With no way to get ...
Intra- and interobserver reproducibility of Bruchs membrane opening minimum rim width measurements with spectral domain ...
Find out information about Bruchs membrane. The membrane of the retina that separates the pigmented layer of the retina from ... the choroid coat of the eye Explanation of Bruchs membrane ... Bruchs membrane , Article about Bruchs membrane by The Free ... Related to Bruchs membrane: Drusen, choriocapillaris, Retinal pigment epithelium. Bruchs membrane. [′brüks ‚mem‚brān] ( ... a href=https://encyclopedia2.thefreedictionary.com/Bruch%27s+membrane,Bruchs membrane,/a,. *Facebook ...
Bruchs Membrane. Bruchs membrane is a highly specialized and multi-laminar structure in our retinas that forms the basis for ... this image from mouse would be a good addition showing the relationship of the basal surface of the RPE with Bruchs membrane. ...
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... separated by Bruchs Membrane - and the photoreceptor cells (rods and cones). Toxic events in the eye very commonly manifest ... The RPE is a single cell layer between the choroid - separated by Bruchs Membrane - and the photoreceptor cells (rods and ...
2). The distance from the internal limiting membrane to the outer border of Bruchs membrane or external limiting membrane was ... accumulation of basal deposits on or within the Bruchs membrane, formation of drusen, and thickening of the Bruchs membrane [ ... internal limiting membrane, BM: Bruchs membrane, ELM: external limiting membrane ... In the fovea, the SFCT was manually measured from the hyperreflective line of the Bruchs membrane to the innermost surface of ...
Transplanted and repopulated retinal pigment epithelial cells on damaged Bruchs membrane in rabbits. ... Transplanted and repopulated retinal pigment epithelial cells on damaged Bruchs membrane in rabbits. Together they form a ...
PERIPAPILLARY ATROPHY WITH LARGE DEHISCENCES IN BRUCH MEMBRANE IN PSEUDOXANTHOMA ELASTICUM. Spaide, Richard F.; Jonas, Jost B. ... Both the confluent areas, termed coquille doeuf and peau dorange appear to be due to calcific infiltration of Bruch membrane ... Large defects in Bruch membrane can develop with these regions of peripapillary atrophy. ... PEAU DORANGE AND ANGIOID STREAKS: Manifestations of Bruch Membrane Pathology. Spaide, Richard F. ...
RGCC localizes to an endothelial cell (yellow arrow) within a choroidal neovascular membrane (CNVM). BrM, Bruchs membrane. Red ...
  • Bruch's membrane is the innermost layer of the choroid. (wikipedia.org)
  • Bruch's membrane consists of five layers (from inside to outside): the basement membrane of the retinal pigment epithelium the inner collagenous zone a central band of elastic fibers the outer collagenous zone the basement membrane of the choriocapillaris The retinal pigment epithelium transports metabolic waste from the photoreceptors across Bruch's membrane to the choroid. (wikipedia.org)
  • Bruch's membrane is present by midterm in fetal development as an elastic sheet. (wikipedia.org)
  • Bruch's membrane thickens with age, slowing the transport of metabolites. (wikipedia.org)
  • Pseudoxanthoma elasticum, myopia and trauma can also cause defects in Bruch's membrane which may lead to choroidal neovascularization. (wikipedia.org)
  • Angioid streaks cause calcification, thickening and breaks in Bruch's membrane. (wikipedia.org)
  • Bruch's membrane was named after the German anatomist Karl Wilhelm Ludwig Bruch. (wikipedia.org)
  • The Bruch's membrane is the blood-retina barrier that separates the RPE cells of the retina from the choroid. (blindness.org)
  • Bruch's membrane is a highly specialized and multi-laminar structure in our retinas that forms the basis for mediating interactions between the retinal pigment epithelium and blood flow from the choroid. (utah.edu)
  • I've not seen many good images online, so figured this image from mouse would be a good addition showing the relationship of the basal surface of the RPE with Bruch's membrane. (utah.edu)
  • Bruch's membrane change with age. (bmj.com)
  • Recent studies have shown that the Bruch's membrane (BM) and retinal pigment epithelium (RPE), visualized on spectral-domain optical coherence tomography (SD-OCT), is deformed anteriorly towards the vitreous in patients with intracranial hypertension and papilledema. (spie.org)
  • In the approach, after the manual placement of the two Bruch's membrane opening (BMO) points, the remaining 18 landmarks are automatically determined using a graph-based segmentation approach. (spie.org)
  • Mice With Cholesterol in Bruch's Membrane: Have We Arrived? (arvojournals.org)
  • Further, aging, the largest risk factor for age-related macular degeneration (AMD), features a marked lipidization of human Bruch's membrane (BrM). (arvojournals.org)
  • Rudolf M Mohi A Dettbarn MC Detection of esterified cholesterol in murine Bruch's membrane wholemounts with a perfringolysin O-based cholesterol marker. (arvojournals.org)
  • The RPE is separated from the choriocapillaris by a multilaminar extracellular matrix called Bruch's membrane (BM), which consists of five layers. (arvojournals.org)
  • Symptomatic abnormalities of dark adaptation in patients with age-related Bruch's membrane change. (bmj.com)
  • Some patients with age-related changes at the level of Bruch's membrane and good visual acuity report poor vision in dim light, fading vision in bright light, and a central scotoma noticeable in the dark. (bmj.com)
  • The findings suggest that visual symptoms reflect abnormality of both scotopic sensitivity and the time course of dark adaptation in patients with age-related Bruch's membrane change. (bmj.com)
  • Bruch's membrane the inner layer of the choroid, separating it from the pigmented layer of the retina. (thefreedictionary.com)
  • Bruch's membrane breakage with a choroidal neovascular membrane, subretinal fluid and retinal hemorrhage in wet AMD. (jirehdesign.com)
  • Bruch's membrane - the transparent innermost layer of the choroid, which is in contact with the retinal pigment epithelium (see retina). (enacademic.com)
  • Optimal laser power to rupture Bruch's membrane and the retinal vein in the pig. (semanticscholar.org)
  • What does the Bruch's membrane do? (maculardegeneration.net)
  • They also creep in between the RPEs and the Bruch's membrane . (maculardegeneration.net)
  • Think of the Bruch's membrane as the store as well as the garbage transfer station. (maculardegeneration.net)
  • The healthy RPEs go to the Bruch's membrane for supplies. (maculardegeneration.net)
  • Now imagine there is a big pile of eye poop that has gotten between the RPEs and the Bruch's membrane. (maculardegeneration.net)
  • The highly effective responses obtained with anti-VEGF injections were attributed to enhanced passage of the bevacizumab through the thinned and degenerated RPE and Bruch's membrane to the subretinal area, thus increasing the drug's efficacy. (thefreedictionary.com)
  • The intracellular lipid accumulation in RPE leads to AMD that appears in the form of Bruch's membrane deposits and drusen. (thefreedictionary.com)
  • 10 Similar changes occur in elastic fibres of the blood vessels, Bruch's membrane of the eye, endocardium and other organs. (thefreedictionary.com)
  • choriocapillaris, Bruch's membrane , RPE, and photoreceptors), and changes in each of these structures may contribute to varying degrees to the onset of AMD (Figure 2). (thefreedictionary.com)
  • The presumed pathogenesis is pressure deformity of the border of Bruch's membrane at the level of the optic nerve head creating a discontinuity of the normal anatomic apposition of the chorioretinal layers. (thefreedictionary.com)
  • 2) They result from a rupture of the elastic tissue in the Bruch's membrane of the retina. (thefreedictionary.com)
  • Using aged submacular human Bruch's membrane explants in organ culture, we reproduced the incomplete and aberrant RPE resurfacing seen in AMD patients following CNV excision [24]. (thefreedictionary.com)
  • A breakdown in the Bruch's membrane usually occurs near drusen deposits, and this is where the new blood vessel growth occurs (neovascularization). (thefreedictionary.com)
  • Statins may prevent the accumulation of basal linear deposit in Bruch's membrane , which occurs in patients with high cholesterol levels. (thefreedictionary.com)
  • It has been postulated that in old age, this material is released from the RPE and renders the overlying Bruch's membrane hydrophobic. (thefreedictionary.com)
  • The TIMP3 mutations may promote excessive growth of blood vessels through Bruch's membrane , which lies below the retina, they speculate. (thefreedictionary.com)
  • The RPE is a single cell layer between the choroid - separated by Bruch's Membrane - and the photoreceptor cells (rods and cones). (ocutox.com)
  • Photoreceptor maintenance is dependent on effective delivery of nutrients from the choroidal circulation by way of the acellular Bruch's membrane and the retinal pigment epithelium. (nih.gov)
  • Aging of Bruch's membrane is associated with thickening, increased cross linking of fibers, and deposition of debris culminating in reduced porosity. (nih.gov)
  • The present study has investigated the effects of aging on the diffusional transport of eight amino acids across Bruch's membrane in 19 human donors. (nih.gov)
  • Transplanted retinal pigment epithelium (RPE) cells hold promise for treatment of age-related macular degeneration (AMD) and Stargardt disease (SD), but it is conceivable that the degenerated host Bruch's membrane (BM) as a natural substrate for RPE might not optimally support transplanted cell survival with correct cellular organization. (edu.au)
  • Progression of AMD is characterized by an increase in the number and size of drusen, extracellular deposits, which accumulate between the retinal pigment epithelium (RPE) and Bruch's membrane (BM) in outer retina. (hindawi.com)
  • Clinically, early stages of AMD are defined by the presence of drusen, the extracellular deposits located between the retinal pigment epithelium (RPE) and Bruch's membrane (BM) (Figure 1 ). (hindawi.com)
  • To develop software to measure the shortest radius in curvature of Bruch's membrane from optical coherence tomography (OCT), and then to apply it to various types of eyes. (bvsalud.org)
  • The horizontal to vertical pixel ratios were changed to 11, and Bruch's membrane was marked automatically on each image. (bvsalud.org)
  • Software to measure the radius of Bruch's membrane curvature was developed. (bvsalud.org)
  • The OCT images of five eyes were analyzed by the software, which could calculate the curvature of Bruch's membrane automatically. (bvsalud.org)
  • An optical coherence tomography (OCT) index, Bruch's membrane opening minimum rim width (BMO-MRW), addresses these deficiencies and has higher diagnostic accuracy for glaucoma. (fau.de)
  • Bruch's membrane allows unhindered passa. (regionh.dk)
  • PURPOSE: It has been proposed that changes in the permeability of Bruch's membrane play a role in the pathogenesis of age-related macular degeneration (AMD). (regionh.dk)
  • This paper investigates, in an in vivo porcine model, the migration of fluorescent latex beads across the Bruch's membrane after subretinal injection. (regionh.dk)
  • In contrast, the larger beads of 4.0 μm did not pass the Bruch's membrane. (regionh.dk)
  • CONCLUSION: Subretinally implanted beads up to 2.0 μm pass the Bruch's membrane intact and cross the blood-ocular barrier. (regionh.dk)
  • The results give reason to consider the role of subretinal clearance and passage of Bruch's membrane in the development of AMD. (regionh.dk)
  • One of the newer indices is the Bruch's membrane opening minimum rim width (BMO-MRW), which is the minimum distance between from the BMO to the inner limiting membrane (ILM). (arizona.edu)
  • AIM:To compare the cube and radial scan patterns of the spectral domain optical coherence tomography (SD-OCT) for quantifying the Bruch's membrane opening minimum rim width (BMO-MRW). (duke.edu)
  • The RPE basal surface is highly infolded and interacts with the underlying Bruch's membrane ( 3 ), an acellular layer separating the RPE from the choriocapillaris. (mcponline.org)
  • It occurs when new blood vessels invade from the choroid and penetrate Bruch's membrane (BM), causing vascular leakage, hemorrhage, and scarring. (frontiersin.org)
  • Firstly, statins might prevent the accumulation of basal linear deposit in Bruch's membrane, which occurs with higher concentrations of plasma cholesterol. (bmj.com)
  • Angioid streaks are cracks in Bruch's membrane. (ahajournals.org)
  • In PXE, Bruch's membrane becomes calcified and brittle. (ahajournals.org)
  • Angioid streaks are irregular disruptions in the Bruch's membrane that are frequently associated with choroidal neovascularization (CNV). (healio.com)
  • Age‐Related Accumulation of 3‐nitrotyrosine and nitro‐A2E in Human Bruch's Membrane. (niu.edu)
  • Modifications to the basement membrane protein, laminin, by glycolaldehyde and A2E: model system for age related changes to Bruch's membrane. (niu.edu)
  • In the posterior segment of the eye, Bruch's membrane, an extracellular matrix between the retinal pigment epithelium (RPE) and the choroid, contains elastic fibers. (scirp.org)
  • Loss of elasticity and enhanced calcification in Bruch's membrane, leads to cracks in it, which is called angioid streaks. (scirp.org)
  • Characterization of Human iPSC-RPE on a Prosthetic Bruch's Membrane Manufactured From Silk Fibroin. (rochester.edu)
  • A layer of extracellular matrix proteins, Bruch's membrane, lies adjacent to the choriocapillaris, and a monolayer of retinal pigment epithelium (RPE) cells divides Bruch's membrane from the photoreceptors. (elifesciences.org)
  • The choriocapillaris, Bruch's membrane, RPE, and photoreceptors function as one unit, with the choriocapillaris providing fuel for phototransduction, and Bruch's membrane and RPE cells filtering and regulating the reciprocal exchange of oxygen, nutrients, biomolecules, and metabolic waste products between the circulation and retina. (elifesciences.org)
  • A striking chemical signature of retinas undergoing degeneration in major eye diseases such as age-related macular degeneration (AMD) and Stargardt disease is the accumulation of these dimers in the retinal pigment epithelium (RPE) and Bruch's membrane (BM). (biologists.org)
  • Capillary lamina of choroid Bruch's membrane Sattler's layer. (nwvlodgings.com)
  • Electron microscopic study of Bruch's membrane was performed in five eyes. (pubmedcentralcanada.ca)
  • Dominantly inherited drusen of Bruch's membrane. (pubmedcentralcanada.ca)
  • Bruch's membrane and disease of the macula. (pubmedcentralcanada.ca)
  • NIR microspectroscopy uncovered clear spectral differences in drusenoid material (Bruch's membrane) and drusen after FN3K treatment. (mdpi.com)
  • On anterior-posterior histological sections, we measured the distance Bruch's membrane end (BME)-optic nerve margin ("Gamma zone"), BME-retinal pigment epithelium (RPE) ("Beta zone"), BME-beginning of non-occluded choriocapillaris, and BME-beginning of photoreceptor layer. (nih.gov)
  • Parapapillary gamma zone (peripapillary sclera without overlying choroid, Bruch's membrane and deep retinal layers) was related with axial globe elongation and was independent of glaucoma. (nih.gov)
  • Beta zone (Bruch's membrane without RPE) was correlated with glaucoma but not with globe elongation. (nih.gov)
  • The technique rejuvenates the 'Bruch's membrane' - a thin layer that lies behind the retina. (medgadget.com)
  • Consider that they tend to arise from the retina above Bruch's membrane. (eyecancer.com)
  • Observers were graded on a scale of I to IV according to the Sarks classification, which correlates fundus appearance and visual acuity with the severity of postmortem histological changes in Bruch's membrane. (osapublishing.org)
  • The majority (about 90%) of patients suffer from dry AMD that is, in the early stage, characterized by the thickening of and structural changes in Bruch's membrane, basal laminar deposits (drusen), and lipofuscin accumulation in the RPE. (molvis.org)
  • Effect of 9 integrin expression on RPE cell adhesion to human Bruch's membrane. (zanran.com)
  • This neovascular membrane destroys the architecture of the outer retina and leads to sudden loss of central vision - wet age related macular degeneration. (wikipedia.org)
  • This membrane is structurally similar to the blood-brain barrier, because the retina is an extension of the brain. (blindness.org)
  • A glassy membrane of the uvea of the eye, lying between the choroid membrane and the pigmented epithelium of the retina. (thefreedictionary.com)
  • The membrane of the retina that separates the pigmented layer of the retina from the choroid coat of the eye. (thefreedictionary.com)
  • 2. The membrane in the retina of the eye through which the receptor portions of the rods and cones protrude. (tabers.com)
  • The blood supply layer of the retina (choroid) is separated from the light (photo) receptors by a thin cellophane-like film called Bruch's (Bruuks's) membrane and a single layer thick row of cells called the retinal pigment epithelium (RPE). (lewrockwell.com)
  • Moderate-to-severe central visual loss is mainly related to foveal involvement with a dehiscence of the underlying Bruch membrane or a neovascular membrane formation under the retina. (medscape.com)
  • In the wet, or exudative, form of age-related macular degeneration (AMD or ARMD), pathologic choroidal neovascular membranes (CNVM) develop under the retina. (medscape.com)
  • Patients with nonexudative AMD can progress to the wet, or exudative, form of AMD, in which pathologic choroidal neovascular membranes (CNVM) develop under the retina. (medscape.com)
  • Capa interna i transparent de la coroide que està en contacte amb l'epiteli pigmentari de la retina. (termcat.cat)
  • Although typical AMD and PCV share a variety of mechanisms by which abnormal angiogenic process occurs at the retinochoroidal interface, PCV has different clinical characteristics such as aneurysm-like dilation at the terminal of choroidal neovascular membranes, less frequent drusen and inner choroidal degeneration due to the thickened choroid. (nature.com)
  • 9. Jaakkola A, Heikkonen J, Tommila P, Laatikainen L, Immonen I. Strontium plaque irradiation of subfoveal neovascular membranes in age-related macular degeneration. (zanran.com)
  • Bereczki, A, Toth, J & Süveges, I 2000, ' Histological examination of the pigment epithelium-Bruch membrane-choriocapillaris complex after macular translocation ', British Journal of Ophthalmology , vol. 84, no. 5, pp. 550-551. (elsevier.com)
  • The RPE-Bruch′s membrane complex for transplantation was surgically developed by dissecting Bruch′s membrane with the choriocapillaris from the medium size choroidal vessel layer at the midperipheral region of the choroid. (bjmu.edu.cn)
  • 12. The method of claim 1 , wherein said retinal target comprises drusen, a macular edema, a tumor, a blood vessel, or an inflammatory membrane. (google.es)
  • Marked visual blurring caused by epiretinal membranes occurs in macular pucker. (tabers.com)
  • Autologous Transplantation of Retinal Pigment Epithelium-Bruch′s Membrane Complex for Hemorrhagic Age-Related Macular Degeneration[J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,2009,50(6):2975-2981. (bjmu.edu.cn)
  • With SD-OCT, one can critically evaluate pathology seen on examination, such as epiretinal membranes and macular degeneration, which can assist in IOL selection and patient counseling. (aao.org)
  • Although many epiretinal membranes can be seen on examination, it is impossible to assess the effect they have on macular architecture without OCT. The following are some examples from my practice. (aao.org)
  • An artificially constructed membrane made of lipids arranged in a bilayer. (tabers.com)
  • Epithelial cells are characterized by the asymmetric distribution of proteins and lipids in their plasma membrane: a basic feature referred to as polarity. (mcponline.org)
  • Physical Properties of the Lipid Bilayer Membrane made of Cortical and Nuclear Bovine Lens Lipids: EPR Spin‐Labeling Studies. (niu.edu)
  • She had a history of laser iridotomy for narrow angles, moderate nuclear sclerosis and cortical cataracts and was interested in cataract surgery with implantation of Crystalens (Bausch & Lomb) or AcrySof IQ ReSTOR (Alcon, Inc.). She had mild epiretinal membrane on examination. (aao.org)
  • With GPME, we analyzed the neuroretinal rim (Bruch membrane opening-minimum rim width [BMO-MRW]) and RNFL. (eur-j-ophthalmol.com)
  • Bowman's membrane a thin layer of basement membrane between the outer layer of stratified epithelium and the substantia propria of the cornea. (thefreedictionary.com)
  • 2. basement membrane . (thefreedictionary.com)
  • The basement membrane is made of a basal lamina along the cell surfaces, coated by a stronger collagen-rich layer (reticular lamina). (tabers.com)
  • The transplantation of the autologous RPE-Bruch′s membrane complex can increase the visual acuity of patients with hemorrhagic AMD. (bjmu.edu.cn)
  • It is believed that the pathology may be a combination of diffuse elastic degeneration of the Bruch membrane, iron deposition in elastic fibers from hemolysis with secondary mineralization, and impairment of nutrition because of sickling, stasis, and small vessel occlusion. (medscape.com)
  • However, in sickle cell disease, Bruch membrane calcification is not a common part of the pathology. (medscape.com)
  • Any of several membranes formed of elastic connective tissue fibers. (tabers.com)
  • Klien proposed a dual mechanism as a cause of these cracks in general, as follows: a primary abnormality of fibers of the Bruch membrane, and an increase in availability of metal salts or a tendency for their deposition, resulting in a secondary brittleness of the membranes. (medscape.com)
  • A membrane formed from excessive proliferation of retinal pigment epithelial cells and extracellular proteins on the retinal surface. (tabers.com)
  • This procedure consisted of excision of the choroidal neovascular membrane and transplantation of autologous retinal pigment epithelium (RPE)-Bruch′s membrane complex. (bjmu.edu.cn)
  • Cracks in the membrane usually occur on the eye muscle/optic nerve head track forcing line. (ahajournals.org)
  • diphtheritic membrane the peculiar false membrane characteristic of diphtheria, formed by coagulation necrosis. (thefreedictionary.com)
  • Descemet's membrane - Vertical section of human cornea from near the margin. (enacademic.com)
  • alveolar-capillary membrane ( alveolocapillary membrane ) a thin tissue barrier through which gases are exchanged between the alveolar air and the blood in the pulmonary capillaries. (thefreedictionary.com)
  • The functional polarity of epithelial cells is dependent on the asymmetric distribution of specific enzymes, signaling molecules, and transport proteins between their apical and basolateral surface membranes ( 1 ). (mcponline.org)
  • The apical surface of cuboidal and columnar epithelial cells commonly faces a luminal cavity and is characterized by the presence of numerous surface membrane elaborations referred to as microvilli. (mcponline.org)
  • It comprises two layers, the basal lamina and the reticular lamina , and is composed of Type IV collagen (which is unique to basement membranes), laminin, fibronectin, and heparan sulfate proteoglycans. (thefreedictionary.com)
  • It is also called the vitreous lamina or Membrane vitriae, because of its glassy microscopic appearance. (wikipedia.org)
  • Such ultrathin membranes may provide a promising vehicle for a functional RPE cell monolayer implantation in the subretinal space in patients with AMD or SD. (edu.au)
  • In some diseases, including pseudoxanthoma elasticum (PXE) and Paget disease , the Bruch membrane may become calcified and brittle with subsequent development of cracks. (medscape.com)
  • [ 1 ] Angioid streaks, also known as Knapp striae, are irregular jagged dehiscences in the mineralized, degenerated, brittle Bruch membrane that typically form alongside force lines exerted by intrinsic and extrinsic ocular muscles that radiate in a centrifugal pattern emanating from the optic disc. (medscape.com)
  • Oil red O binding neutral lipid represents a major age-related deposition in the Bruch membrane (BrM) and the first identified druse component. (northwestern.edu)
  • Inner limiting membrane Nerve fiber layer Ganglion cell layer Inner plexiform layer Inner nuclear layer Outer plexiform layer Outer nuclear layer External limiting membrane Layer of rods and cones Retinal pigment epithelium. (nwvlodgings.com)
  • 1. a membrane between the outer root sheath and inner fibrous layer of a hair follicle. (thefreedictionary.com)
  • The membrane that forms the outer boundary of a cell. (tabers.com)
  • 1. The outer membrane of the embryonic neural tube. (tabers.com)
  • it is a thin hyaline membrane between the substantia propria and the endothelial layer of the cornea. (thefreedictionary.com)
  • membranes peripheral to the macula are generally asymptomatic, while those involving the macula or adjacent to it may cause reduction in vision, visual distortion, and diplopia. (thefreedictionary.com)
  • False membrane. (tabers.com)
  • The fibrinous false membrane on the mucous surfaces in diphtheria. (tabers.com)
  • The membrane through which gases must pass as they diffuse from air to blood (oxygen) or blood to air (carbon dioxide), including the alveolar fluid and surfactant, cell of the alveolar wall, interstitial space (tissue fluid), and cell of the capillary wall. (tabers.com)
  • impaired oral mucous membrane a nursing diagnosis approved by the North American Nursing Diagnosis Association, defined as disruptions of the lips and soft tissue of the oral cavity. (thefreedictionary.com)
  • Changes in the integrity and health of the oral mucous membrane can occur as a characteristic of such medical disorders as periodontal disease, uncontrolled diabetes mellitus, oral cancer, and infection with herpes. (thefreedictionary.com)
  • A membrane of fibrinous exudate on a mucous surface of a membrane, as in croup or diphtheria. (tabers.com)