Brucellosis
Brucellosis, Bovine
Brucella
Brucella melitensis
Brucella abortus
Brucella suis
Brucella Vaccine
Rose Bengal
Agglutination Tests
Brucella canis
Zoonoses
Coombs Test
Cattle Diseases
Macedonia (Republic)
Orchitis
Goats
Epididymitis
Serum Albumin, Bovine
Herpesvirus 1, Bovine
Streptomycin
Rifampin
Livestock
Milk
Seroepidemiologic Studies
Veterinarians
Cattle
Animals, Wild
Leukemia Virus, Bovine
Enzyme-Linked Immunosorbent Assay
Complement Fixation Tests
Central Nervous System Bacterial Infections
Veterinary Medicine
Arthritis, Infectious
Diarrhea Viruses, Bovine Viral
Panuveitis
Bison
Tuberculosis, Bovine
Cetacea
Immunoproteins
Sensitivity and Specificity
Cheese
Pancytopenia
Dairy Products
Antibody response to antigens distinct from smooth lipopolysaccharide complex in Brucella infection. (1/168)
The smooth lipopolysaccharide complex of the outer surface of smooth Brucella abortus cells is believed to be the antigenic component involved in serological tests routinely used for the diagnosis of brucellosis. Sera from cattle vaccinated or infected with B. abortus generally contain antibody directed toward the smooth lipopolysaccharide complex. The brucella organism contains a large number of other antigenically distinct components. The biological significance of some of these antigens has been demonstrated by showing that sera from infected cattle have precipitins to these components. These sera revealed up to seven distinct lines in immunoelectrophoresis with a protein-rich antigen mixture prepared from rough strain B. abortus 45/20, whereas sera from strain 19-vaccinated cattle did not reveal these lines at 4 or more months after vaccination. Monospecific antisera were prepared against six antigens in this mixture, and the purification of two of them by antibody affinity chromatography is described. (+info)Comparison of sensitivity and specificity of purified lymphocyte and whole-blood in vitro lymphocyte stimulation assays in detection of Brucella abortus infection in cattle. (2/168)
A study was conducted to compare the sensitivity and specificity of purified lymphocyte and whole-blood in vitro lymphocyte stimulation assays in detection of Brucella abortus infection in cattle. Cattle used were infected with B. abortus field strains or strain 19. Peripheral blood was collected, and lymphocytes for the technique. The blood for the whole-blood lymphocyte stimulation assay was diluted 10-fold with RPMI 1640 medium (without additional serum supplement) and cultured. The two tests were run simultaneously, and B. abortus soluble antigen or concanavalin A was added to the cultures. The cultures were incubated for 6 days and assayed for [3H] thymidine incorporation into their DNA. Generally, cultures of the purified lymphocyte stimulation assay had higher counts per minute than those of the whole-blood lymphocyte stimulation assay, but the stimulation ratios for the two tests were comparable. The two assays were comparable in terms of their sensitivity and specificity as applied to detection of brucella infection in cattle. (+info)Brucella antigen preparations for in vitro lymphocyte immunostimulation assays in bovine brucellosis. (3/168)
Three Brucella antigen preparations, Brucella abortus soluble antigen, B. abortus strain 45/20 enriched protein antigen, and B. melitensis enriched protein antigen, were compared in terms of their ability to induce specific in vitro lymphocyte immunostimulation responses. Lymphocytes were prepared from peripheral blood of cattle with different exposure experiences to B. abortus organisms. Lymphocytes were processed by the Ficoll-diatrizoate technique, and results were assayed for [3H]tymidine incorporation into DNA by liquid scintillation spectrometry. The three Brucella antigen preparations were compared both at the optimal concentrations of protein and on an equal-dry-weight basis. The results were evaluated in terms of specific lymphocyte immunostimulation responses induced by each preparation and the degree of correlation with infection. B. abortus soluble antigen-induced lymphocyte immunostimulation response correlated best with infection status followed by B. abortus 45/20 and B. melitensis enriched protein antigens. The implications of these findings are discussed and a hypothesis is proposed. (+info)Utilization of a specific in vitro lymphocyte immunostimulation assay as an aid in detection of brucella-infected cattle not detected by serological tests. (4/168)
Studies using the in vitro lymphocyte stimulation test (LST) were conducted with cattle in a dairy herd with a high percentage of reactors to several serological tests for brucellosis. Lymphocytes were prepared from peripheral bovine blood by the Ficoll-diatrizoate technique. Lymphocytes were cultured using microtitration culture plates. Brucella abortus soluble antigen, at a concentration of 4.4 microgram/culture, was added to the appropriate wells of microtitration culture plates and incubated for 6 days. The lymphocyte stimulation responses were measured by assaying for [3H]thymidine incorporation into DNA. Seroagglutination tests were conducted simultaneously with the LST, and tissues were collected after slaughter of the cattle for bacteriological culture to isolate B. abortus. All 21 animals studied were serologically negative for anti-brucella antibodies. Two of the 21 animals were classified as infected with Brucella by the LST, and B. abortus biotype 1 was isolated from tissues of these same two animals. The LST exhibited significant sensitivity and specificity in this study, and more observations of this nature might strengthen the application of this assay as an aid in the diagnosis of brucellosis. (+info)Identification of an IS711 element interrupting the wboA gene of Brucella abortus vaccine strain RB51 and a PCR assay to distinguish strain RB51 from other Brucella species and strains. (5/168)
Brucella abortus vaccine strain RB51 is a natural stable attenuated rough mutant derived from the virulent strain 2308. The genetic mutations that are responsible for the roughness and the attenuation of strain RB51 have not been identified until now. Also, except for an assay based on pulsed-field gel electrophoresis, no other simple method to differentiate strain RB51 from its parent strain 2308 is available. In the present study, we demonstrate that the wboA gene encoding a glycosyltransferase, an enzyme essential for the synthesis of O antigen, is disrupted by an IS711 element in B. abortus vaccine strain RB51. Exploiting this feature, we developed a PCR assay that distinguishes strain RB51 from all other Brucella species and strains tested. (+info)Human and animal epidemic of Yersinia enterocolitica O:9, 1989-1997, Auvergne, France. (6/168)
Yersinia enterocolitica O:9 infections were reported in Auvergne in 1988 to 1989, while brucellosis due to Brucella abortus was almost eliminated. The serologic cross-reactions between the two bacteria complicated the diagnosis of brucellosis cases. In 1996, human cases of Yersinia enterocolitica O:9 infection were detected, with a peak incidence of 12 cases. Veterinary surveillance could have predicted the emergence of this disease in humans. (+info)The adjuvant effect of a single dose of interleukin-12 on murine immune responses to live or killed Brucella abortus strain RB51. (7/168)
This study was designed to determine if a single 0.5 microg administration of recombinant murine interleukin-12 (IL-12) would influence immune responses of mice vaccinated with live or killed Brucella abortus strain RB51 (SRB51). Mice were vaccinated intraperitoneally with 5 x 10(8) cfu of live or gamma-irradiated SRB51 bacteria alone, or in combination with 0.5 microg of IL-12. Control mice received saline or 0.5 microg of IL-12. Serologic responses and spleen weights after vaccination were greater in mice vaccinated with live SRB51 when compared to mice receiving killed SRB51 or control treatments. Administration of a single dose of IL-12 as a vaccine adjuvant did not influence immune responses, clearance of live SRB51, or resistance against B. abortus strain 2308 (S2308) challenge. The results of this study suggest that a single administration of 0.5 microg of IL-12 at the time of vaccination does not have significant adjuvant effects on vaccine-induced immune responses against live or killed Brucella. (+info)Complement fixation test to assess humoral immunity in cattle and sheep vaccinated with Brucella abortus RB51. (8/168)
The live attenuated Brucella abortus strain RB51 is a rifampin-resistant, lipopolysaccharide (LPS) O-chain-deficient mutant of virulent B. abortus 2308. The reduced O-chain content in RB51 prevents this bacterium from inducing antibodies detectable by the conventional serologic tests for bovine brucellosis diagnosis that mainly identify antibodies to LPS. The absence of available serologic tests for RB51 also complicates the diagnosis of possible RB51 infections in humans exposed to this strain. The purpose of this study was to evaluate the suitability of a complement fixation (CF) test performed with the rough strain B. abortus RB51, previously deprived of anticomplementary activity, in detecting anti-B. abortus RB51 antibodies in cattle and sheep experimentally vaccinated with this strain. The results of this study showed that a CF test with RB51 as the antigen is able to specifically detect antibodies following RB51 vaccination in cattle and sheep. In addition, this method could be a useful tool for detecting B. abortus RB51 infection in humans. (+info)There are several types of brucellosis, including:
1. Brucella abortus: This type is primarily found in cattle and is the most common form of the disease in humans.
2. Brucella suis: This type is found in pigs and is less common in humans.
3. Brucella melitensis: This type is found in sheep, goats, and other animals, and is more virulent than B. abortus.
4. Brucella canis: This type is found in dogs and is rare in humans.
The symptoms of brucellosis can vary depending on the severity of the infection and the individual's overall health. Common symptoms include:
1. Fever
2. Headache
3. Joint pain
4. Muscle pain
5. Swelling of the lymph nodes and spleen
6. Fatigue
7. Loss of appetite
8. Weight loss
In severe cases, brucellosis can cause complications such as:
1. Endocarditis (infection of the heart valves)
2. Meningitis (inflammation of the lining around the brain and spinal cord)
3. Osteomyelitis (infection of the bone)
4. Testicular inflammation in men
5. Epididymitis (inflammation of the epididymis, a tube that carries sperm from the testicle to the penis)
6. Inflammation of the heart muscle and valves
7. Pneumonia
8. Inflammation of the liver and spleen
Brucellosis is diagnosed through a combination of physical examination, laboratory tests, and imaging studies. Treatment typically involves antibiotics, and early treatment can help prevent complications. Prevention measures include avoiding contact with infected animals and ensuring proper hygiene practices when handling livestock or wild game.
Once infected, humans can experience a range of symptoms including fever, headache, muscle pain, and fatigue. In severe cases, the infection can spread to the bones and joints, causing swelling and pain. Brucellosis can also lead to complications such as endocarditis (inflammation of the heart valves) and meningitis (inflammation of the lining around the brain and spinal cord).
Brucellosis in cows is typically diagnosed through a combination of physical examination, laboratory tests, and blood samples. Treatment typically involves antibiotics, but it is important to detect and treat the infection early to prevent complications. Prevention measures include vaccination of animals, proper handling and disposal of animal products, and avoiding contact with infected animals or their products.
In addition to its medical significance, brucellosis has also been associated with significant economic losses in the livestock industry due to reduced milk production and fertility issues in infected animals.
Zoonoses (zoonosis) refers to infectious diseases that can be transmitted between animals and humans. These diseases are caused by a variety of pathogens, including bacteria, viruses, parasites, and fungi, and can be spread through contact with infected animals or contaminated animal products.
Examples of Zoonoses
Some common examples of zoonoses include:
1. Rabies: a viral infection that can be transmitted to humans through the bite of an infected animal, typically dogs, bats, or raccoons.
2. Lyme disease: a bacterial infection caused by Borrelia burgdorferi, which is spread to humans through the bite of an infected blacklegged tick (Ixodes scapularis).
3. Toxoplasmosis: a parasitic infection caused by Toxoplasma gondii, which can be transmitted to humans through contact with contaminated cat feces or undercooked meat.
4. Leptospirosis: a bacterial infection caused by Leptospira interrogans, which is spread to humans through contact with contaminated water or soil.
5. Avian influenza (bird flu): a viral infection that can be transmitted to humans through contact with infected birds or contaminated surfaces.
Transmission of Zoonoses
Zoonoses can be transmitted to humans in a variety of ways, including:
1. Direct contact with infected animals or contaminated animal products.
2. Contact with contaminated soil, water, or other environmental sources.
3. Through vectors such as ticks, mosquitoes, and fleas.
4. By consuming contaminated food or water.
5. Through close contact with an infected person or animal.
Prevention of Zoonoses
Preventing the transmission of zoonoses requires a combination of personal protective measures, good hygiene practices, and careful handling of animals and animal products. Some strategies for preventing zoonoses include:
1. Washing hands frequently, especially after contact with animals or their waste.
2. Avoiding direct contact with wild animals and avoiding touching or feeding stray animals.
3. Cooking meat and eggs thoroughly to kill harmful bacteria.
4. Keeping pets up to date on vaccinations and preventative care.
5. Avoiding consumption of raw or undercooked meat, particularly poultry and pork.
6. Using insect repellents and wearing protective clothing when outdoors in areas where vectors are prevalent.
7. Implementing proper sanitation and hygiene practices in animal housing and husbandry.
8. Implementing strict biosecurity measures on farms and in animal facilities to prevent the spread of disease.
9. Providing education and training to individuals working with animals or in areas where zoonoses are prevalent.
10. Monitoring for and reporting cases of zoonotic disease to help track and control outbreaks.
Conclusion
Zoonoses are diseases that can be transmitted between animals and humans, posing a significant risk to human health and animal welfare. Understanding the causes, transmission, and prevention of zoonoses is essential for protecting both humans and animals from these diseases. By implementing appropriate measures such as avoiding contact with wild animals, cooking meat thoroughly, keeping pets up to date on vaccinations, and implementing proper sanitation and biosecurity practices, we can reduce the risk of zoonotic disease transmission and protect public health and animal welfare.
There are several types of spondylitis, including:
1. Ankylosing spondylitis (AS): This is the most common form of spondylitis and primarily affects the lower back. It can cause stiffness, pain, and reduced mobility in the spine.
2. Psoriatic arthritis (PsA): This type of spondylitis affects both the joints and the spine, causing inflammation and pain. It often occurs in people with psoriasis, a skin condition that causes red, scaly patches.
3. Enteropathic spondylitis: This is a rare form of spondylitis that occurs in people with inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis.
4. Undifferentiated spondylitis: This type of spondylitis does not fit into any other category and may be caused by a variety of factors.
The symptoms of spondylitis can vary depending on the specific type and severity of the condition, but may include:
1. Back pain that is worse with activity and improves with rest
2. Stiffness in the back, particularly in the morning or after periods of inactivity
3. Redness and warmth in the affected area
4. Swelling in the affected joints
5. Limited range of motion in the spine
6. Fatigue
7. Loss of appetite
8. Low-grade fever
Spondylitis can be diagnosed through a combination of physical examination, medical history, and imaging tests such as X-rays or MRIs. Treatment typically involves a combination of medication and lifestyle modifications, such as exercise, physical therapy, and stress management techniques. In severe cases, surgery may be necessary to repair or replace damaged joints or tissue.
It's important to note that spondylitis is a chronic condition, meaning it cannot be cured but can be managed with ongoing treatment and lifestyle modifications. With proper management, many people with spondylitis are able to lead active and fulfilling lives.
Cattle diseases refer to any health issues that affect cattle, including bacterial, viral, and parasitic infections, as well as genetic disorders and environmental factors. These diseases can have a significant impact on the health and productivity of cattle, as well as the livelihoods of farmers and ranchers who rely on them for their livelihood.
Types of Cattle Diseases
There are many different types of cattle diseases, including:
1. Bacterial diseases, such as brucellosis, anthrax, and botulism.
2. Viral diseases, such as bovine viral diarrhea (BVD) and bluetongue.
3. Parasitic diseases, such as heartwater and gapeworm.
4. Genetic disorders, such as polledness and cleft palate.
5. Environmental factors, such as heat stress and nutritional deficiencies.
Symptoms of Cattle Diseases
The symptoms of cattle diseases can vary depending on the specific disease, but may include:
1. Fever and respiratory problems
2. Diarrhea and vomiting
3. Weight loss and depression
4. Swelling and pain in joints or limbs
5. Discharge from the eyes or nose
6. Coughing or difficulty breathing
7. Lameness or reluctance to move
8. Changes in behavior, such as aggression or lethargy
Diagnosis and Treatment of Cattle Diseases
Diagnosing cattle diseases can be challenging, as the symptoms may be similar for different conditions. However, veterinarians use a combination of physical examination, laboratory tests, and medical history to make a diagnosis. Treatment options vary depending on the specific disease and may include antibiotics, vaccines, anti-inflammatory drugs, and supportive care such as fluids and nutritional supplements.
Prevention of Cattle Diseases
Preventing cattle diseases is essential for maintaining the health and productivity of your herd. Some preventative measures include:
1. Proper nutrition and hydration
2. Regular vaccinations and parasite control
3. Sanitary living conditions and frequent cleaning
4. Monitoring for signs of illness and seeking prompt veterinary care if symptoms arise
5. Implementing biosecurity measures such as isolating sick animals and quarantining new animals before introduction to the herd.
It is important to work closely with a veterinarian to develop a comprehensive health plan for your cattle herd, as they can provide guidance on vaccination schedules, parasite control methods, and disease prevention strategies tailored to your specific needs.
Conclusion
Cattle diseases can have a significant impact on the productivity and profitability of your herd, as well as the overall health of your animals. It is essential to be aware of the common cattle diseases, their symptoms, diagnosis, treatment, and prevention methods to ensure the health and well-being of your herd.
By working closely with a veterinarian and implementing preventative measures such as proper nutrition and sanitary living conditions, you can help protect your cattle from disease and maintain a productive and profitable herd. Remember, prevention is key when it comes to managing cattle diseases.
Symptoms of orchitis may include:
* Scrotal pain
* Swelling of the scrotum
* Redness and tenderness of the scrotum
* Fever
* Chills
* Abdominal pain
* Nausea and vomiting
Treatment for orchitis typically involves antibiotics to clear up any bacterial infections, as well as supportive care such as rest, ice packs, and over-the-counter pain medication. In severe cases, hospitalization may be necessary to monitor and treat the condition.
Prevention of orchitis includes avoiding close contact with people who have the infection, practicing safe sex, and maintaining good hygiene. Vaccination against certain types of bacteria that can cause orchitis, such as the H. influenzae type b (Hib) vaccine, can also help prevent the condition.
It is important to seek medical attention if symptoms of orchitis are present, as early treatment can help prevent complications and improve outcomes.
Reference:
American Urological Association. (2019). Epididymitis. Retrieved from
Sheep diseases can be caused by a variety of factors, including bacteria, viruses, parasites, and environmental factors. Here are some common sheep diseases and their meanings:
1. Scrapie: A fatal neurological disorder that affects sheep and goats, caused by a prion.
2. Ovine Progressive Pneumonia (OPP): A contagious respiratory disease caused by Mycobacterium ovipneumoniae.
3. Maedi-Visna: A slow-progressing pneumonia caused by a retrovirus, which can lead to OPP.
4. Foot-and-Mouth Disease (FMD): A highly contagious viral disease that affects cloven-hoofed animals, including sheep and goats.
5. Bloat: A condition caused by gas accumulation in the rumen, which can lead to abdominal pain and death if not treated promptly.
6. Pneumonia: An inflammation of the lungs, often caused by bacteria or viruses.
7. Cryptosporidiosis: A diarrheal disease caused by Cryptosporidium parvum, which can be fatal in young lambs.
8. Babesiosis: A blood parasitic disease caused by Babesia oviparasites, which can lead to anemia and death if left untreated.
9. Fascioliasis: A liver fluke infection that can cause anemia, jaundice, and liver damage.
10. Anthrax: A serious bacterial disease caused by Bacillus anthracis, which can be fatal if left untreated.
Sheep diseases can have a significant impact on the health and productivity of flocks, as well as the economy of sheep farming. It is important for sheep farmers to be aware of these diseases and take appropriate measures to prevent and control them.
1. Caprine arthritis-encephalitis (CAE): A viral disease that affects the joints and central nervous system of goats.
2. Caseous lymphadenitis (CLA): A bacterial infection that causes abscesses in the lymph nodes and other organs.
3. Contagious ecthyma (Orf): A viral disease that causes skin lesions and scarring.
4. Goat pox: A viral disease that causes fever, weakness, and skin lesions.
5. Pneumonia: A bacterial or viral infection of the lungs that can be caused by a variety of pathogens.
6. Scabies: A parasitic infestation that causes skin irritation and hair loss.
7. Tetanus: A neurological disorder caused by a bacterial toxin that affects muscle contractions.
8. Toxoplasmosis: A parasitic infection that can cause fever, anemia, and other symptoms in goats.
9. Urinary tract infections (UTIs): Bacterial infections of the urinary system that can affect both male and female goats.
10. Vitamin deficiencies: Deficiencies in vitamins such as vitamin A, D, or E can cause a range of health problems in goats, including skin conditions, poor appetite, and weakness.
Goat diseases can be diagnosed through physical examination, laboratory tests, and imaging studies. Treatment depends on the specific disease and may involve antibiotics, antiviral medications, or supportive care such as fluid therapy and nutritional supplements. Prevention is key in managing goat diseases, and this includes maintaining good hygiene, providing clean water and a balanced diet, and vaccinating goats against common diseases.
Definition:
Veterinary abortion refers to the intentional termination of a pregnancy in an animal, typically a farm or domesticated animal such as a dog, cat, horse, cow, or pig. The procedure is performed by a veterinarian and is usually done for reasons such as unwanted breeding, disease or genetic disorders in the fetus, or to prevent overpopulation of certain species.
Types of Veterinary Abortion:
1. Spontaneous Abortion (Miscarriage): This occurs naturally when the pregnancy is terminated by natural causes such as infection or trauma.
2. Induced Abortion: This is performed by a veterinarian using various methods such as injection of drugs or surgical procedures to terminate the pregnancy.
Methods of Veterinary Abortion:
1. Drug-induced abortion: This method involves administering medication to the animal to cause uterine contractions and expulsion of the fetus.
2. Surgical abortion: This method involves surgical intervention to remove the fetus from the uterus, usually through a small incision in the abdomen.
3. Non-surgical abortion: This method uses a device to remove the fetus from the uterus without making an incision.
Complications and Risks of Veterinary Abortion:
1. Infection: As with any surgical procedure, there is a risk of infection.
2. Hemorrhage: Excessive bleeding can occur during or after the procedure.
3. Uterine rupture: In rare cases, the uterus may rupture during the procedure.
4. Incomplete abortion: In some cases, not all of the fetus may be removed, leading to complications later on.
5. Scarring: Scars may form in the uterus or abdomen after the procedure, which can lead to reproductive problems in the future.
Prevention of Unwanted Pregnancies in Animals:
1. Spaying/neutering: This is the most effective way to prevent unwanted pregnancies in animals.
2. Breeding management: Proper breeding management, including selecting healthy and fertile breeding animals, can help reduce the risk of unwanted pregnancies.
3. Use of contraceptives: Hormonal contraceptives, such as injection or implants, can be used in some species to prevent pregnancy.
4. Behavioral management: In some cases, behavioral management techniques, such as separation or rehoming of animals, may be necessary to prevent unwanted breeding.
Ethical Considerations of Veterinary Abortion:
1. Animal welfare: The procedure should only be performed when necessary and with the intention of improving the animal's welfare.
2. Owner consent: Owners must provide informed consent before the procedure can be performed.
3. Veterinarian expertise: The procedure should only be performed by a licensed veterinarian with experience in the procedure.
4. Alternative options: All alternative options, such as spaying/neutering or rehoming, should be considered before performing an abortion.
Conclusion:
Veterinary abortion is a complex issue that requires careful consideration of ethical and practical factors. While it may be necessary in some cases to prevent the suffering of unwanted litters, it is important to approach the procedure with caution and respect for animal welfare. Owners must provide informed consent, and the procedure should only be performed by a licensed veterinarian with experience in the procedure. Alternative options, such as spaying/neutering or rehoming, should also be considered before performing an abortion. Ultimately, the decision to perform a veterinary abortion should be made with the intention of improving the animal's welfare and quality of life.
CNS bacterial infections can cause a wide range of symptoms, including fever, headache, confusion, seizures, and loss of consciousness. In severe cases, these infections can lead to meningitis, encephalitis, or abscesses in the brain or spinal cord.
The diagnosis of CNS bacterial infections is based on a combination of clinical findings, laboratory tests, and imaging studies. Laboratory tests may include blood cultures, cerebrospinal fluid (CSF) cultures, and polymerase chain reaction (PCR) tests to identify the causative bacteria. Imaging studies, such as computed tomography (CT) or magnetic resonance imaging (MRI), may be used to visualize the extent of the infection.
Treatment of CNS bacterial infections typically involves the use of antibiotics, which can help to clear the infection and prevent further complications. In some cases, surgical intervention may be necessary to drain abscesses or relieve pressure on the brain or spinal cord.
Preventive measures for CNS bacterial infections include vaccination against certain types of bacteria, such as Streptococcus pneumoniae and Haemophilus influenzae, good hygiene practices, and appropriate use of antibiotics. Early diagnosis and treatment are critical to preventing long-term neurological damage or death.
In conclusion, CNS bacterial infections can be serious and potentially life-threatening conditions that require prompt diagnosis and treatment. Understanding the causes, symptoms, diagnosis, treatment, and prevention of these infections is essential for effective management and optimal outcomes for patients affected by them.
A type of arthritis that is caused by an infection in the joint, typically bacterial or viral. The most common form of infectious arthritis is Lyme disease, which is caused by the bacterium Borrelia burgdorferi and is transmitted through the bite of an infected blacklegged tick. Other types of infectious arthritis include septic arthritis (caused by bacterial infection) and reactive arthritis (caused by a bacterial or viral infection in another part of the body).
Symptoms: Pain, swelling, redness, warmth, and limited range of motion in the affected joint. Fever may also be present.
Diagnosis: A diagnosis is made based on symptoms, physical examination, blood tests (such as a complete blood count or a polymerase chain reaction test to detect the presence of bacteria or viruses), and imaging studies (such as X-rays or ultrasound).
Treatment: Treatment typically involves antibiotics to eradicate the infection, as well as medication to manage symptoms such as pain and inflammation. In severe cases, surgery may be necessary to repair damaged tissue or joints.
The most common symptoms of bovine mastitis include:
1. Swelling and redness of the udder
2. Increased temperature of the affected quarter
3. Pain or discomfort in the udder
4. Decreased milk production
5. Abnormal milk appearance (e.g., clots, pus, or blood)
If left untreated, mastitis can lead to more severe complications such as abscesses, septicemia, or even death of the animal. Therefore, early detection and proper treatment are crucial to prevent the spread of infection and reduce the severity of clinical signs.
Diagnosis of bovine mastitis is typically based on a combination of clinical examination, milk culture, and laboratory tests (e.g., blood counts, serum biochemistry). Treatment involves antibiotics, supportive care (e.g., fluids, pain management), and identification of the underlying cause to prevent future occurrences.
Prevention of bovine mastitis is key to maintaining a healthy and productive dairy herd. This includes proper sanitation and hygiene practices, regular milking techniques, and effective dry cow therapy. Vaccination against common mastitis-causing pathogens may also be considered in some cases.
Overall, bovine mastitis is a significant health issue in dairy cattle that can have significant economic and welfare implications for farmers and the industry as a whole. Proper diagnosis, treatment, and prevention strategies are essential to maintain a healthy and productive herd.
The symptoms of bovine tuberculosis can vary depending on the severity of the infection and the organs affected. Common symptoms include:
* Coughing or difficulty breathing
* Weight loss and loss of condition
* Fever
* Swollen lymph nodes
* Enlarged liver or spleen
* Poor milk production in lactating cows
* Intestinal problems, such as diarrhea or constipation
If left untreated, bovine tuberculosis can lead to serious complications, such as pneumonia, pleurisy, and peritonitis. It can also spread to other animals in the herd, making it important to identify and isolate infected animals promptly.
Diagnosis of bovine tuberculosis typically involves a combination of physical examination, laboratory tests, and imaging studies. Skin tests, such as the Mantoux test or the single-dose intradermal test, can detect exposure to the bacteria, but they may not always provide accurate results in animals with low levels of antibodies. Blood tests, such as the interferon gamma (IFN-γ) test or the QuantiFERON® test, can detect the presence of TB antigens in the blood, but these tests may also have limitations.
Treatment of bovine tuberculosis typically involves a combination of antibiotics and supportive care to manage symptoms and prevent complications. The most commonly used antibiotics include isoniazid, streptomycin, and pyrazinamide. In severe cases, surgical intervention may be necessary to remove infected tissue or repair damaged organs.
Prevention of bovine tuberculosis primarily involves controlling the spread of the disease through control of the mycobacteria that cause it. Measures such as testing and removal of infected animals, use of clean needles and equipment, and proper disposal of animal carcasses can help prevent the spread of the disease. Additionally, vaccination of animals with a live bacille Calmette-Guérin (BCG) vaccine has been shown to be effective in preventing TB infections.
In conclusion, bovine tuberculosis is a significant health concern for cattle and other animals, as well as humans who may be exposed to infected animals or contaminated products. Early diagnosis and treatment are essential to prevent the spread of the disease and manage symptoms in affected animals. Prevention measures such as testing and removal of infected animals, use of clean needles and equipment, and proper disposal of animal carcasses can help control the spread of the disease.
Symptoms of pancytopenia may include fatigue, weakness, shortness of breath, and increased risk of bleeding or infection. Treatment depends on the underlying cause, but may include blood transfusions, antibiotics, or immunosuppressive medications. In severe cases, pancytopenia can lead to anemia, infections, or bleeding complications that can be life-threatening.
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Tuberculosis5
- Many diseases are endemic in the studied species (brucellosis, foot and mouth disease, tuberculosis, rabies) and the main clinical signs of several diseases are diarrhoea, abortion, lameness and respiratory problems. (who.int)
- Letter from the Chief Veterinary Officer, Sheila Voas, to cattle keepers in Scotland regarding changes to the Tuberculosis (Scotland) Order 2023 and a reminder about reporting abortions in cattle for Brucellosis surveillance. (gov.scot)
- I am writing to make you aware that tighter controls to reduce the risk of spreading Bovine Tuberculosis (TB) will come into force on 18 May under the Tuberculosis (Scotland) Order 2023. (gov.scot)
- If you would like more information on bovine tuberculosis in Scotland, please visit our web page on bovine TB . (gov.scot)
- In Texas, for instance, since the beginning of the year, TAHC has investigated 30 brucellosis reactors, more than 300 bulls affected by bovine trichomoniasis , and 22 bovine tuberculosis cases. (beefmagazine.com)
Brucella11
- Three isolates were identified from 105 blood samples from humans with brucellosis and 50 samples of milk and tissues from infected cows and they were all Brucella melitensis biovar 3. (who.int)
- A cross-sectional study was conducted from July to November 2017 in Lindi District to estimate the seroprevalence of brucellosis in cattle, assess farmers' knowledge and to identify risk factors for Brucella infection in animals. (ac.tz)
- Brucellosis is a worldwide zoonosis caused by Brucella spp. (cdc.gov)
- The Brucella RB51 strain is resistant to some antibiotics that would normally be used to prevent or treat brucellosis. (cdc.gov)
- Enfermedad del ganado bovino, producida por bacterias del género BRUCELLA, que causa abortos en las etapas finales de la gestación. (bvsalud.org)
- Isolation of a field strain of Brucella abortus from RB51-vaccinated- and brucellosis-seronegative bovine yearlings that calved normally. (bvsalud.org)
- SVANOVIR ® Brucella -Ab C-ELISA is a multispecies assay ideal for use in situations of low and high prevalence of brucellosis, and for confirming results from herd screening tests. (svanova.com)
- Human Brucella seroprevalence in Ugandan communities is not well known since most of the health centers are not able to screen for brucellosis. (peertechzpublications.com)
- Brucellosis is caused by gram-negative facultative intracellular coccobacilli of Brucella genus [2,5]. (peertechzpublications.com)
- The bacterium swine brucellosis ( Brucella suis ) is transmitted by breeding (semen, reproductive fluids) and ingestion of the bacteria (placenta and aborted fetuses, milk and urine). (extension.org)
- Swine brucellosis can cause a false positive test for bovine brucellosis ( Brucella abortus ) in cattle. (extension.org)
Caprine1
- France has been free of bovine, ovine, and caprine brucellosis (caused by B . abortus or B . melitensis ) since 2003 ( 1 ). (cdc.gov)
Treat brucellosis1
- While there are ways to treat brucellosis if it is caught early enough, the cost-prohibitive nature of antibiotics means it is not practical to treat livestock and wildlife. (wylr.net)
Bacterial2
- Brucellosis is a contagious bacterial zoonotic disease of public health importance worldwide. (ac.tz)
- Bacterial diseases (e.g., swine brucellosis and tularemia) are not generally spread this way, but other diseases such as salmonellosis, foot rot, intestinal bacteria, viruses, and parasites are commonly transmitted by this route. (extension.org)
Prevalence3
- Data about the prevalence of brucellosis in animals are incomplete and cover only a small proportion of the national livestock. (who.int)
- For example, bovine leukemia virus (BLV) commonly infects and causes lymphosarcoma in cattle and sheep, and the prevalence of infection in herds can be as high as over 40% (Burny and Mammerickx, 1987). (cdc.gov)
- In this review, we summarised human and animal brucellosis, prevalence of infections in Nigeria, and economic impacts on production. (who.int)
Humans2
- All bovine sera were needed in order to establish the most useful subjected initially to the rose Bengal plate tests for use in Algeria, both in humans and test (RBT) and the buffer acidified plate animals. (who.int)
- Swine brucellosis is often called undulant fever when humans contract it because body temperature rises and falls along with flu-like symptoms. (extension.org)
Tularemia1
- Three diseases that cause the most concern are swine brucellosis, psuedorabies, and tularemia, although, feral hogs harbor other diseases as well. (extension.org)
Disease8
- Although steady progress is being made in brucellosis control in this region, serious difficulties remain due the complexity of the epidemiology of the disease. (who.int)
- Brucellosis : a history of the disease and its eradication from cattle in Great Britain / written by E. Madden. (who.int)
- Ellis explains suspension of the state's brucellosis testing program in August 2011 was the impetus behind the Texas Animal Disease Traceability (TADT) program. (beefmagazine.com)
- As in other states, Texas had utilized the requisite ID tags for disease eradication programs such as brucellosis testing as a provisional ID system that could be used to trace beef cows for other disease concerns. (beefmagazine.com)
- The breeding in brucellosis control in this region, serious system is traditional without application of difficulties remain due the complexity of the any standard in hygiene, food rationing or epidemiology of the disease. (who.int)
- Prion agents cause the subacute severe neurologic disease known as bovine spongiform encephalopathy (BSE) or 'mad cow' disease in cattle, and scrapie in sheep. (cdc.gov)
- There is historical and current evidence that some of these agents are transmissible to workers and subjects in the general population, and cause zoonotic acute infection and disease in them such as leptospirosis, Q-fever, brucellosis, vesicular stomatitis, etc., as reviewed in Johnson (1984). (cdc.gov)
- It is believed that this review will guide researchers on the state of brucellosis in developing countries where the disease is still endemic, using Nigeria as a case study. (who.int)
Reactors1
- Proportions of positive reactors to brucellosis were 6.0% and 5.2% based on RBPT and c-ELISA respectively. (ac.tz)
Goat1
- Domestic animals (cattle, sheep and goat, pigs, dogs etc) are highly susceptible to brucellosis. (who.int)
Melitensis biovar1
- In early 2012, an outbreak of bovine and human brucellosis caused by B . melitensis biovar 3 ( Bmel 3) occurred in a French Alp massif (mountainous region), where the last reported outbreak occurred in 1999 ( Technical Appendix Figure) ( 2 ). (cdc.gov)
Brucellose1
- En utilisant l'épreuve de fixation du complément comme méthode de référence pour les tests de confirmation, on a constaté que le test au Rivanol était plus sensible mais moins spécifique que l'épreuve d'agglutination en tube pour le dépistage de la brucellose. (who.int)
Vaccine1
- The bovine vaccine reduces the risk of people contracting brucellosis from infected cows. (cdc.gov)
Zoonosis1
- Brucellosis is a highly contagious zoonosis of major public health and veterinary concern globally [1]. (peertechzpublications.com)
Diseases1
- Brucellosis is notifiable in Sweden and is governed by the epizootic diseases act. (slu.se)
Herd2
- Brucellosis was eradicated from the U.S. cattle herd a number of years ago, with the exceptions of Idaho, Montana, Texas and Idaho," he continued. (wylr.net)
- A positive test for bovine brucellosis results in a quarantine of the cattle herd, ultimately leaving the cattle rancher with a financial loss. (extension.org)
Arthritis1
- French Authorities authorized the killing of 12 seropositive or diseased alpine ibex with clinical signs of brucellosis (i.e., arthritis or orchitis) among 30 captured animals. (cdc.gov)
Livestock1
- Questionnaires were administered to 60 livestock keepers and blood samples collected from 300 cattle for brucellosis analysis using Rose Bengal Plate Test and competitive-enzyme linked immune-sorbent (cELISA) assay tests. (ac.tz)
Milk3
- Because health officials have no direct way to let people know they may have drunk contaminated milk, everyone who consumed milk from Udder Milk in the past 6 months should receive antibiotics now to avoid having long-term health effects from the bacteria," said William Bower, M.D., team lead for the CDC group that investigates brucellosis, the illness caused by RB51. (cdc.gov)
- Doctors can learn more about testing patients for RB51 and which antibiotics to prevent or cure infection at https://www.cdc.gov/brucellosis/clinicians/rb51-raw-milk.html . (cdc.gov)
- People who have consumed the milk and other products made from Udder Milk raw milk should check themselves daily for fever for one month after they last drank the milk and watch for other brucellosis symptoms for six months. (cdc.gov)
Concern1
- Worland - As cattle producers interact with wildlife on grazing permits in northwest Wyoming, brucellosis continues to create concern outside of the Designated Surveillance Area (DSA). (wylr.net)
Human1
- Brucellosis is worldwide and affects human, cattle health and international trade. (peertechzpublications.com)
Occur1
- Brucellosis can occur in any age group, but mainly found in young men between the ages of 20 and 40 years because of occupational hazards. (who.int)
Placenta1
- Generally, brucellosis manifest in female animals as abortion, retained placenta, stillbirth and death of young ones soon after birth. (who.int)
Seropositive1
- On the feedgrounds, brucellosis rates run between 15 and 30 percent seropositive. (wylr.net)
Bacteria2
Animals1
- Concentration of animals contributes to transmission of brucellosis. (wylr.net)
Positive2
History2
- History of abortion (p=0.00) and improper disposal of aborted materials (p=0.04) were found to be significantly associated with occurrence of bovine brucellosis in cattle. (ac.tz)
- In Wyoming, Galey noted that the recent history of brucellosis in cattle began in 2004, when a case was found near an elk feedground near Pinedale. (wylr.net)
Study1
- This study reports for the first time on occurrence of brucellosis in Lindi District and highlights on the possible risk factors for its transmission in cattle. (ac.tz)
Spread2
Found2
- Using the complement fixation test as the gold standard for confirmatory tests, the Rivanol test was found to be more sensitive but less specific than tube agglutination in detecting brucellosis infection. (who.int)
- This is the first time we have found brucellosis in elk outside the DSA," he comments. (wylr.net)
Free1
- This is to support Scotland's Brucellosis surveillance and to ensure we continue to have confidence in our officially Brucellosis free status. (gov.scot)
Public health1
- The endemicity of brucellosis has remained a threat in low- income countries of sub-Saharan Africa and South Asia and has multiple economic implications across agriculture and public health sectors, and broader implications on economic and social development sectors. (who.int)
Test1
- The complement fixation test evaluate a number of serological tests and was (CFT) used as the gold standard for to discuss some epidemiological aspects of measuring the sensitivity and specificity of brucellosis. (who.int)
Countries2
- An intensive government effort has been made in Algeria as well as in other North African countries to eradicate brucellosis or at least to keep the infection at a manageable level [4]. (who.int)
- Vaccination against brucellosis in African countries to eradicate brucellosis or cattle is still forbidden in Algeria. (who.int)
Reports1
- Google and Google Scholar were used to retrieve articles used for this review, which included published research articles and local, national and international reports on brucellosis. (who.int)
Important1
- Brucellosis is considered the most important of the zoonoses in the Mediterranean region and its economic impact is great [1-3]. (who.int)