Brucella canis

Brucella

Brucellosis

Dog Diseases

Brucella abortus

Brucella melitensis

Toxocara canis

Agglutination Tests

Dogs

Ehrlichia canis

Brucella Vaccine

Antibodies, Bacterial

Brucella ovis

Brucella canis

Dog health

Brucella

Αr7 RNA

List of MeSH codes (B03)

Αr45 RNA

Αr14 RNA

Αr9 RNA

Αr15 RNA

Brucella abortus

Brucella suis

Brucellosis

Biovar

Parasites and pathogens of wolves

List of infectious diseases

Wolf hunting

List of vaccine topics

United States biological weapons program

Brucellosis12

• The less mucoid strain of Brucella canis or M- strain is used for the serologic diagnosis of canine brucellosis. (cdc.gov)
• Brucella canis is the causative agent of canine brucellosis, which causes contagious abortion, orchiepididymitis, and uveitis. (cdc.gov)
• Taking into account the unprotected exposure to B. canis M-, brucellosis was suspected, and blood samples were drawn for culture and serologic studies. (cdc.gov)
• Three types of the bacteria that cause brucellosis - Brucella abortus , Brucella melitensis and Brucella suis - are designated as select agents. (cdc.gov)
• Interest in brucellosis has been increasing because of the growing phenomena of international tourism and migration, in addition to the potential use of Brucella as a biological weapon. (medscape.com)
• Brucellosis is a contagious disease caused by the bacterium brucellosis, specifically Brucella canis in dogs, which can result in infertility, abortions, and stillbirths. (akc.org)
• None of the exposed persons reported having previously had brucellosis or being unintentionally inoculated with Brucella vaccine. (cdc.gov)
• Editorial Note: Brucellosis, also known as 'undulant fever' or 'Bangs disease,' is a systemic infection caused by Brucella sp. (cdc.gov)
• Although brucellosis is mainly a bacterial disease of animals, several species of Brucella bacteria are known to cause disease in humans. (medscape.com)
• Bacteria of the genus Brucella are the causative agents of brucellosis, a worldwide zoonosis that affects a broad range of mammals, including livestock and humans. (mgc.ac.cn)
• Secara medis, bisa jadi induk anjing tadi menderita brucellosis yang merupakan penyakit infeksi yang disebabkan oleh bakteri brucella canis. (enigmablogger.com)
• Brucellosis is caused by Brucella species, which are gram-negative bacteria. (msdmanuals.com)

Abortus10

• In contrast to other Brucella species, which are pathogenic for humans ( B. abortus, B. melitensis, B. suis ) and yield smooth colonies, B. canis colonies are naturally rough. (cdc.gov)
• Brucella is a genus of Gram-negative coccobacilli, and it groups together several species including Brucella abortus , Brucella melitensis, Brucella canis and Brucella suis. (osmosis.org)
• So, B. abortus is transmitted by cattle, B. melitensis is transmitted by small ruminants such as goats and sheep, B. canis is transmitted by dogs and B. suis is transmitted by swine and rodents. (osmosis.org)
• On May 26-27, 1997, nine persons (a farmer, four veterinary clinicians, and four veterinary students) in Manhattan, Kansas, participated in an attempted vaginal delivery, a cesarean delivery, and a necropsy on a stillborn calf that died because of Brucella abortus infection. (cdc.gov)
• small Gram-negative coccobacilli that can infect cattle (infection with B. abortus), goats and sheep (B. melitensis), pigs (B. suis), and dogs (B. canis). (cdc.gov)
• Brucella abortus biovar 1 str. (up.ac.za)
• Finally, people can become infected with Brucella RB51, a strain of B abortus that is used to vaccinate cattle in the United States and other parts of the world. (medscape.com)
• The genus Brucella consists of six classic species, designated on the basis of host preference, antigenic and biochemical characteristics as Brucella melitensis (goats and sheep), Brucella abortus (cattle), Brucella suis (pigs), Brucella canis (dogs), Brucella ovis (sheep) and Brucella neotomae (wood rats). (mgc.ac.cn)
• 2005. Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis . (mgc.ac.cn)
• 2008. Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes. (mgc.ac.cn)

Suis2

• 2002. The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts. (mgc.ac.cn)
• Generally, B. melitensis and B. suis are more pathogenic than other Brucella species. (msdmanuals.com)

Bacteria6

• A new government risk assessment updated on Monday (18 September) found 97 dogs had tested positive for the Brucella canis bacteria in the year to June, largely linked to pets brought in from overseas. (scotsman.com)
• How is the Brucella canis bacteria affecting dogs in the UK? (scotsman.com)
• The number of dogs who have tested positive for the Brucella canis bacteria has been steadily rising since 2020 - largely linked to pets being brought in from overseas. (scotsman.com)
• Now, Brucella it's a non-motile bacteria that doesn't form spores. (osmosis.org)
• Now, Brucella is a very slow growing bacteria, so colonies usually grow in the solid medium after 6 to 8 weeks of incubation. (osmosis.org)
• Canine brucellose is caused by the brucella canis bacteria. (monvet.com)

Infection7

• We report a clinical and immunologic study of a human infection by the B. canis M- strain that shows that this strain can produce human disease similar to that produced by wild-type B. canis . (cdc.gov)
• Exposure to most species of Brucella , such as those associated with certain types of animals, could potentially lead to infection. (cdc.gov)
• The epidemiological investigation did not identify the source of the infection , given the time elapsed from the onset of abortions to the definitive diagnosis of B. canis infection in the kennel. (bvsalud.org)
• The lack of updated data on B. canis genome sequences in the public databases, together with the limited information retrieved from the epidemiological investigations on the outbreak, hampered identification of the source of B. canis infection . (bvsalud.org)
• A Brucella infection in dogs is considered very difficult to treat, and may never be fully cured. (scotsman.com)
• Young dogs presenting with recurring lameness or back pain should be screened for B canis infection. (avma.org)
• However, B canis and Brucella RB51 won't show up on serology, so culture is needed to confirm the infection. (medscape.com)

Zoonotic3

• This project evaluated the prevalence and distribution of the zoonotic bacterium Brucella canis in breeding dogs in Ontario. (oahn.ca)
• Brucella canis can devastate a kennel, and it is zoonotic, meaning it can infect humans too. (akc.org)
• Brucella canis is a zoonotic bacterial pathogen of dogs that is notoriously difficult to diagnose and treat. (avma.org)

20222

• The UK Health Security Agency (UKHSA) says there have been three cases of humans becoming infected with Brucella canis since 2022. (scotsman.com)
• Diagnostic records from the Animal Health Diagnostic Center at Cornell University were retrospectively reviewed (2017-2022) for dogs that underwent repeat B canis serologic testing. (avma.org)

Species7

• Two weeks later blood cultures indicated a Brucella species that was later typed as B. canis . (cdc.gov)
• First, there may be direct contact with infected animals - and the host is different for each Brucella species. (osmosis.org)
• Because the diagnostic test and treatment vary, it is important to identify whether a patient is infected with Brucella , and if so, which [species of] Brucella is causing disease. (medscape.com)
• Each species of Brucella has distinct risk factors. (medscape.com)
• Most clinical diagnostic laboratories are able to run serologic tests, which detect an antibody response to most of the Brucella species. (medscape.com)
• Two new brucella species, provisionally called B. pinnipediae and B. cetaceae , have been isolated from marine hosts within the past few years. (mgc.ac.cn)
• 2011. Interactions of the human pathogenic Brucella species with their hosts. (mgc.ac.cn)

Bacterium1

• While B. canis has typically been considered to be a rare bacterium in Ontario, mainly associated with imported dogs, this investigation was started in response to identification of a potential problem with B. canis in commercial dog breeding kennels in southwestern Ontario. (oahn.ca)

Gram-negative coccobacilli2

• Brucellae are aerobic gram-negative coccobacilli that possess a unique ability to invade both phagocytic and nonphagocytic cells and to survive in the intracellular environment by finding ways to avoid the immune system. (medscape.com)
• Brucella is a gram-negative coccobacilli that can infect humans and animals. (osmosis.org)

Humans2

• Humans can become infected with B canis when an infected pet dog is brought into their home. (avma.org)
• Although less common in humans, B canis is found in dogs all over the world, including the United States, and generally causes mild illness in people. (medscape.com)

Virulence factors1

• However, Brucella has a few virulence factors that it uses to avoid destruction. (osmosis.org)

Infections2

• Therefore, serologic tests that use suspensions of smooth brucellae are not useful in diagnosing B. canis infections ( 2 ) . (cdc.gov)
• B. canis (from dogs) has caused sporadic infections. (msdmanuals.com)

Canine1

• Our objectives were to describe the clinical presentation and outcomes in dogs treated for B canis and evaluate the performance of the quantitative serologic canine Brucella multiplex (CBM) assay for monitoring treatment response. (avma.org)

Genome2

• 2002. The genome sequence of the facultative intracellular pathogen Brucella melitensis . (mgc.ac.cn)
• 2005. Whole-genome analyses of speciation events in pathogenic Brucellae . (mgc.ac.cn)

Serologic1

• Since suspensions of wild-type B. canis tend to aggregate even in the absence of specific antibodies, a less mucoid variant termed M-, which does not produce autoagglutination is used for serologic diagnosis ( 3 ) . (cdc.gov)

Abortions1

• Brucella organisms, which are small aerobic intracellular coccobacilli, localize in the reproductive organs of host animals, causing abortions and sterility. (medscape.com)

Multiplex1

• The isolates were identified as B. canis by standard microbiological methods and a Bruce-ladder multiplex PCR . (bvsalud.org)

Kennel2

• First Isolation of Brucella canis from a breeding kennel in Italy. (bvsalud.org)
• Brucella canis has been isolated for the first time in Italy in a commercial breeding kennel. (bvsalud.org)

Blood cultures2

• Blood cultures performed 2 weeks after antimicrobial therapy ended were negative for B. canis . (cdc.gov)
• Brucella is usually isolated on blood cultures, with biphasic methods like the Ruiz-Castaneda methods. (osmosis.org)

Biological1

• While he continues to handle B. canis M-, cultures are now performed under strict biological safety measures (biological safety cabinet, personal protection including goggles, gloves and mask, and autoclaving of contaminated material). (cdc.gov)

Risks3

• The UK's chief veterinary officer, Dr Christine Middlemiss, said: "We take the risks posed by Brucella canis very seriously and require all cases to be reported to the Animal Plant Health Agency. (scotsman.com)
• We continue to work closely with our colleagues at [the UK Health Security Agency], dog welfare groups and vets to minimise the risks posed and recommend prospective owners make sure any dog imported from regions where Brucella canis is present is tested before arrival. (scotsman.com)
• Further prospective studies are needed to determine the ideal B canis treatment regimen and the magnitude of public health risks associated with maintaining neutered B canis- infected animals as pets. (avma.org)

Agglutination2

• Conventional tests for antibodies to smooth brucellae (agglutination, complement fixation) yielded negative results. (cdc.gov)
• In contrast, slide agglutination for B. canis was strongly positive with undiluted serum and was also positive at 1:10 dilution. (cdc.gov)

Prospective1

• If considering importing a dog into the UK (or rescuing a dog that has been imported) we recommend prospective owners ensure testing for other diseases including Brucella canis is carried out before the movement takes place. (scotsman.com)

Cases1

• Although acquired outside the United States, these cases are not diagnosed until after the patient has returned home, due to the long incubation period for Brucella . (medscape.com)

Person1

• But what is the risk of a person picking up Brucella canis, and how safe are dogs at home? (scotsman.com)

Spread1

• The spread of B. canis beyond the tested region will also hopefully be explored. (oahn.ca)

Human1

• Brucella can gain entry into the human body through breaks in the skin, mucous membranes, conjunctivae, and respiratory and gastrointestinal (GI) tracts. (medscape.com)