Brucella abortus. Medical search

A species of the genus BRUCELLA whose natural hosts are cattle and other bovidae. Abortion and placentitis are frequently produced in the pregnant animal. Other mammals, including humans, may be infected.

A genus of gram-negative, aerobic bacteria that causes BRUCELLOSIS. Its cells are nonmotile coccobacilli and are animal parasites and pathogens. The bacterium is transmissible to humans through contact with infected dairy products or tissue.

Infection caused by bacteria of the genus BRUCELLA mainly involving the MONONUCLEAR PHAGOCYTE SYSTEM. This condition is characterized by fever, weakness, malaise, and weight loss.

A disease of cattle caused by bacteria of the genus BRUCELLA leading to abortion in late pregnancy. BRUCELLA ABORTUS is the primary infective agent.

A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.

A species of the genus BRUCELLA whose natural hosts are sheep and goats. Other mammals, including humans, may be infected. In general, these organisms tend to be more virulent for laboratory animals than BRUCELLA ABORTUS and may cause fatal infections.

A species of the genus BRUCELLA which are pathogenic to SHEEP.

A species of gram-negative bacteria infecting DOGS, the natural hosts, and causing canine BRUCELLOSIS. It can also cause a mild infection in humans.

Premature expulsion of the FETUS in animals.

Immunoglobulins produced in a response to BACTERIAL ANTIGENS.

Tests that are dependent on the clumping of cells, microorganisms, or particles when mixed with specific antiserum. (From Stedman, 26th ed)

Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.

A four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.

A genus of the family CHLAMYDIACEAE comprising gram-negative non CHLAMYDIA TRACHOMATIS-like species infecting vertebrates. Chlamydophila do not produce detectable quantities of glycogen. The type species is CHLAMYDOPHILA PSITTACI.

A genus of the family Bovidae having two species: B. bison and B. bonasus. This concept is differentiated from BUFFALOES, which refers to Bubalus arnee and Syncerus caffer.

Substances elaborated by bacteria that have antigenic activity.

A species of gram-negative bacteria, primarily infecting SWINE, but it can also infect humans, DOGS, and HARES.

Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1.

A species of gram-negative, obligately aerobic rods. Motility occurs by peritrichous flagella. (From Bergey's Manual of Determinative Bacteriology, 9th ed)

Suspensions of attenuated or killed bacteria administered for the prevention or treatment of infectious bacterial disease.

Proteins found in any species of bacterium.

The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.

An encapsulated lymphatic organ through which venous blood filters.

A bright bluish pink compound that has been used as a dye, biological stain, and diagnostic aid.

Deoxyribonucleic acid that makes up the genetic material of bacteria.

The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)

Ruminants of the family Bovidae consisting of Bubalus arnee and Syncerus caffer. This concept is differentiated from BISON, which refers to Bison bison and Bison bonasus.

Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)

Proteins isolated from the outer membrane of Gram-negative bacteria.

Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.

Diseases of domestic and mountain sheep of the genus Ovis.

Benzoate derivatives substituted by one or more hydroxy groups in any position on the benzene ring.

Any of numerous agile, hollow-horned RUMINANTS of the genus Capra, in the family Bovidae, closely related to the SHEEP.

Modulation of endocytosis in nuclear factor IL-6(-/-) macrophages is responsible for a high susceptibility to intracellular bacterial infection. (1/780)

Activated macrophages kill bacteria, a function known to depend on the expression of NF-IL-6. Here, it is demonstrated that the attenuated Brucella abortus vaccine strain 19 replicates much better in NF-IL-6-/- than in NF-IL-6(+/+) and NF-IL-6(+/+)-activated murine macrophages and at levels comparable to those observed in normal macrophages infected with the pathogenic strain 2308. The role of NF-IL-6 in the inhibition of intracellular bacterial replication is related to its control of endocytosis and membrane fusion between endosomes and Brucella-containing phagosomes. Addition of the granulocyte-CSF (G-CSF), whose induction is impaired in NF-IL-6(-/-) macrophages, restores both endocytosis and the morphology of endosomes, together with bactericidal activity. Regulation of membrane traffic in endocytosis by G-CSF whose expression is controlled by NF-IL-6 may explain how a host cell can control intracellular bacterial replication. (+info)

Immunity to Brucella in mice vaccinated with a fraction (F8) or a killed vaccine (H38) with or without adjuvant. Level and duration of immunity in relation to dose of vaccine, recall injection and age of mice. (2/780)

Immunity to Brucella in the mouse, assessed by bacterial spleen counts 15 days after intraperitoneal inoculation of a standard challenge of B. abortus 544, has been studied with two vaccines, one experimental, composed of a fraction of the bacterial cell-wall (F8) extracted from B. abortus 99, the other of killed whole bacteria, B. melitensis 53 H38, taken as reference (H38). The level of primary immunity depended on the dose of vaccine, the presence of oil adjuvant and the age of the mouse. The presence of adjuvant enabled the immunization to F8 to continue beyond the first month, to reach its maximum around the fourth month, and to remain stable for at least 7 months. A booster injection 3 or 6 months after the primary vaccination reinforced existing immunity but did not increase it beyond a certain level. The effect of the recall injection was clearly demonstrated with low doses which gave a lower level of primary immunity. (+info)

Murine macrophage-lymphocyte interactions: scanning electron microscopic study. (3/780)

Light and scanning electron microscopic observations revealed murine macrophage-lymphocyte interactions involving the initial contact of peritoneal, spleen, or thymus lymphocytes with peritoneal macrophage processes or microprocesses followed by clustering of lymphocytes over the central nuclear area of the macrophages. Lymphocyte-lymphocyte clustering was not observed in the absence of macrophages. Attachment and subsequent clustering appeared not to require the presence of serum or antigen; the attachment of allogeneic or xenogeneic lymphocytes was comparable to that seen in the syngeneic system, but central clustering of these lymphocytes failed to occur. No attachment or clustering was observed when thymic lymphocytes were cultured with thymus derived fibroblasts rather than with peritoneal macrophages. Lymphocyte attachment to immune, antigen-activated, syngeneic macrophages occurred more rapidly than that to normal unstimulated syngeneic macrophages; however, lymphocytes attached to the "activated" macrophages appeared to be killed by a nonphagocytic mechanism. A similar increase in the rate of lymphocyte attachment to macrophages occurred in the presence of migration inhibitory factor. Subsequent lymphocyte clustering on macrophages was observed in the migration inhibitory factor-stimulated cultures. In addition, lymphocyte-macrophage interactions similar to those in vitro were observed to occur in vivo on intraperitoneally implanted cover slips. (+info)

Plaque-forming cells in mice after experimental infection with Brucella abortus. (4/780)

Cells producing antibody to brucella lipopolysaccharide were detected in spleens of mice infected with Brucella abortus 19 by a hemolytic plaque assay. The appearance of immunoglobulin M-producing cells preceded humoral antibodies. The primary plaques were observed 5 days after inoculation, and they were still present by day 70. (+info)

Antibody response to antigens distinct from smooth lipopolysaccharide complex in Brucella infection. (5/780)

The smooth lipopolysaccharide complex of the outer surface of smooth Brucella abortus cells is believed to be the antigenic component involved in serological tests routinely used for the diagnosis of brucellosis. Sera from cattle vaccinated or infected with B. abortus generally contain antibody directed toward the smooth lipopolysaccharide complex. The brucella organism contains a large number of other antigenically distinct components. The biological significance of some of these antigens has been demonstrated by showing that sera from infected cattle have precipitins to these components. These sera revealed up to seven distinct lines in immunoelectrophoresis with a protein-rich antigen mixture prepared from rough strain B. abortus 45/20, whereas sera from strain 19-vaccinated cattle did not reveal these lines at 4 or more months after vaccination. Monospecific antisera were prepared against six antigens in this mixture, and the purification of two of them by antibody affinity chromatography is described. (+info)

The siderophore 2,3-dihydroxybenzoic acid is not required for virulence of Brucella abortus in BALB/c mice. (6/780)

2,3-Dihydroxybenzoic acid (DHBA) is the only siderophore described for Brucella, and previous studies suggested that DHBA might contribute to the capacity of these organisms to persist in host macrophages. Employing an isogenic siderophore mutant (DeltaentC) constructed from virulent Brucella abortus 2308, however, we found that production of DHBA is not required for replication in cultured murine macrophages or for the establishment and maintenance of chronic infection in the BALB/c mouse model. (+info)

Structure and function prediction of the Brucella abortus P39 protein by comparative modeling with marginal sequence similarities. (7/780)

A methodology is proposed to solve a difficult modeling problem related to the recently sequenced P39 protein. This sequence shares no similarity with any known 3D structure, but a fold is proposed by several threading tools. The difficulty in aligning the target sequence on one of the proposed template structures is overcome by combining the results of several available prediction methods and by refining a rational consensus between them. In silico validation of the obtained model and a preliminary cross-check with experimental features allow us to state that this borderline prediction is at least reasonable. This model raises relevant hypotheses on the main structural features of the protein and allows the design of site-directed mutations. Knowing the genetic context of the P39 reading frame, we are now able to suggest a function for the P39 protein: it would act as a periplasmic substrate-binding protein. (+info)

Comparison of sensitivity and specificity of purified lymphocyte and whole-blood in vitro lymphocyte stimulation assays in detection of Brucella abortus infection in cattle. (8/780)

A study was conducted to compare the sensitivity and specificity of purified lymphocyte and whole-blood in vitro lymphocyte stimulation assays in detection of Brucella abortus infection in cattle. Cattle used were infected with B. abortus field strains or strain 19. Peripheral blood was collected, and lymphocytes for the technique. The blood for the whole-blood lymphocyte stimulation assay was diluted 10-fold with RPMI 1640 medium (without additional serum supplement) and cultured. The two tests were run simultaneously, and B. abortus soluble antigen or concanavalin A was added to the cultures. The cultures were incubated for 6 days and assayed for [3H] thymidine incorporation into their DNA. Generally, cultures of the purified lymphocyte stimulation assay had higher counts per minute than those of the whole-blood lymphocyte stimulation assay, but the stimulation ratios for the two tests were comparable. The two assays were comparable in terms of their sensitivity and specificity as applied to detection of brucella infection in cattle. (+info)

There are several types of brucellosis, including:

1. Brucella abortus: This type is primarily found in cattle and is the most common form of the disease in humans.
2. Brucella suis: This type is found in pigs and is less common in humans.
3. Brucella melitensis: This type is found in sheep, goats, and other animals, and is more virulent than B. abortus.
4. Brucella canis: This type is found in dogs and is rare in humans.

The symptoms of brucellosis can vary depending on the severity of the infection and the individual's overall health. Common symptoms include:

1. Fever
2. Headache
3. Joint pain
4. Muscle pain
5. Swelling of the lymph nodes and spleen
6. Fatigue
7. Loss of appetite
8. Weight loss

In severe cases, brucellosis can cause complications such as:

1. Endocarditis (infection of the heart valves)
2. Meningitis (inflammation of the lining around the brain and spinal cord)
3. Osteomyelitis (infection of the bone)
4. Testicular inflammation in men
5. Epididymitis (inflammation of the epididymis, a tube that carries sperm from the testicle to the penis)
6. Inflammation of the heart muscle and valves
7. Pneumonia
8. Inflammation of the liver and spleen

Brucellosis is diagnosed through a combination of physical examination, laboratory tests, and imaging studies. Treatment typically involves antibiotics, and early treatment can help prevent complications. Prevention measures include avoiding contact with infected animals and ensuring proper hygiene practices when handling livestock or wild game.

Once infected, humans can experience a range of symptoms including fever, headache, muscle pain, and fatigue. In severe cases, the infection can spread to the bones and joints, causing swelling and pain. Brucellosis can also lead to complications such as endocarditis (inflammation of the heart valves) and meningitis (inflammation of the lining around the brain and spinal cord).

Brucellosis in cows is typically diagnosed through a combination of physical examination, laboratory tests, and blood samples. Treatment typically involves antibiotics, but it is important to detect and treat the infection early to prevent complications. Prevention measures include vaccination of animals, proper handling and disposal of animal products, and avoiding contact with infected animals or their products.

In addition to its medical significance, brucellosis has also been associated with significant economic losses in the livestock industry due to reduced milk production and fertility issues in infected animals.

Definition:

Veterinary abortion refers to the intentional termination of a pregnancy in an animal, typically a farm or domesticated animal such as a dog, cat, horse, cow, or pig. The procedure is performed by a veterinarian and is usually done for reasons such as unwanted breeding, disease or genetic disorders in the fetus, or to prevent overpopulation of certain species.

Types of Veterinary Abortion:

1. Spontaneous Abortion (Miscarriage): This occurs naturally when the pregnancy is terminated by natural causes such as infection or trauma.
2. Induced Abortion: This is performed by a veterinarian using various methods such as injection of drugs or surgical procedures to terminate the pregnancy.

Methods of Veterinary Abortion:

1. Drug-induced abortion: This method involves administering medication to the animal to cause uterine contractions and expulsion of the fetus.
2. Surgical abortion: This method involves surgical intervention to remove the fetus from the uterus, usually through a small incision in the abdomen.
3. Non-surgical abortion: This method uses a device to remove the fetus from the uterus without making an incision.

Complications and Risks of Veterinary Abortion:

1. Infection: As with any surgical procedure, there is a risk of infection.
2. Hemorrhage: Excessive bleeding can occur during or after the procedure.
3. Uterine rupture: In rare cases, the uterus may rupture during the procedure.
4. Incomplete abortion: In some cases, not all of the fetus may be removed, leading to complications later on.
5. Scarring: Scars may form in the uterus or abdomen after the procedure, which can lead to reproductive problems in the future.

Prevention of Unwanted Pregnancies in Animals:

1. Spaying/neutering: This is the most effective way to prevent unwanted pregnancies in animals.
2. Breeding management: Proper breeding management, including selecting healthy and fertile breeding animals, can help reduce the risk of unwanted pregnancies.
3. Use of contraceptives: Hormonal contraceptives, such as injection or implants, can be used in some species to prevent pregnancy.
4. Behavioral management: In some cases, behavioral management techniques, such as separation or rehoming of animals, may be necessary to prevent unwanted breeding.

Ethical Considerations of Veterinary Abortion:

1. Animal welfare: The procedure should only be performed when necessary and with the intention of improving the animal's welfare.
2. Owner consent: Owners must provide informed consent before the procedure can be performed.
3. Veterinarian expertise: The procedure should only be performed by a licensed veterinarian with experience in the procedure.
4. Alternative options: All alternative options, such as spaying/neutering or rehoming, should be considered before performing an abortion.

Conclusion:

Veterinary abortion is a complex issue that requires careful consideration of ethical and practical factors. While it may be necessary in some cases to prevent the suffering of unwanted litters, it is important to approach the procedure with caution and respect for animal welfare. Owners must provide informed consent, and the procedure should only be performed by a licensed veterinarian with experience in the procedure. Alternative options, such as spaying/neutering or rehoming, should also be considered before performing an abortion. Ultimately, the decision to perform a veterinary abortion should be made with the intention of improving the animal's welfare and quality of life.

Sheep diseases can be caused by a variety of factors, including bacteria, viruses, parasites, and environmental factors. Here are some common sheep diseases and their meanings:

1. Scrapie: A fatal neurological disorder that affects sheep and goats, caused by a prion.
2. Ovine Progressive Pneumonia (OPP): A contagious respiratory disease caused by Mycobacterium ovipneumoniae.
3. Maedi-Visna: A slow-progressing pneumonia caused by a retrovirus, which can lead to OPP.
4. Foot-and-Mouth Disease (FMD): A highly contagious viral disease that affects cloven-hoofed animals, including sheep and goats.
5. Bloat: A condition caused by gas accumulation in the rumen, which can lead to abdominal pain and death if not treated promptly.
6. Pneumonia: An inflammation of the lungs, often caused by bacteria or viruses.
7. Cryptosporidiosis: A diarrheal disease caused by Cryptosporidium parvum, which can be fatal in young lambs.
8. Babesiosis: A blood parasitic disease caused by Babesia oviparasites, which can lead to anemia and death if left untreated.
9. Fascioliasis: A liver fluke infection that can cause anemia, jaundice, and liver damage.
10. Anthrax: A serious bacterial disease caused by Bacillus anthracis, which can be fatal if left untreated.

Sheep diseases can have a significant impact on the health and productivity of flocks, as well as the economy of sheep farming. It is important for sheep farmers to be aware of these diseases and take appropriate measures to prevent and control them.

B. abortus also affects bison. Brucella has twelve different kinds of species, one being Brucella abortus. Some of the other ... The prokaryotic B. abortus is non-spore-forming, non-motile and aerobic. Brucella abortus enters phagocytes that invade human ... "Humans and Brucella Species". "Brucellosis: Brucella Abortus" (PDF). Kaden, R.; Ferrari, S.; Jinnerot, T.; Lindberg, M.; Wahab ... Brucella abortus is a Gram-negative bacterium in the family Brucellaceae and is one of the causative agents of brucellosis. The ...

https://en.wikipedia.org/wiki/Brucella_abortus

MARR AG, WILSON PW (1954). "The alanine racemase of Brucella abortus". Arch. Biochem. Biophys. 49 (2): 424-33. doi:10.1016/0003 ...

https://en.wikipedia.org/wiki/Alanine_racemase

Sinclair provided unpublished data on Brucella abortus. Wright, J. A.; Rook, John Allan Fynes; Panes, John Joseph (October 1969 ... "Infection of sheep in Yorkshire with Salmonella abortus ovis". Veterinary Record. London: John Wiley & Sons. 84 (13): 350. ISSN ...

https://en.wikipedia.org/wiki/Brian_Sinclair_(veterinary_surgeon)

"Studies, in the dissociation and immunity to Brucella abortus .. , WorldCat.org". www.worldcat.org. Retrieved 2022-11-10. " ... Her undergraduate research considered immunity to Brucella abortus. She remained in Washington for doctoral research, ...

https://en.wikipedia.org/wiki/Rose_Payne

ALTENBERN RA, HOUSEWRIGHT RD (1953). "Transaminases in smooth Brucella abortus, strain 19" (PDF). J. Biol. Chem. 204 (1): 159- ...

https://en.wikipedia.org/wiki/Alanine—oxo-acid_transaminase

Dong, Hao; Peng, Xiaowei; Wang, Ning; Wu, Qingmin (2014-05-01). "Identification of novel sRNAs in Brucella abortus 2308". FEMS ... "Identification of two small regulatory RNAs linked to virulence in Brucella abortus 2308". Molecular Microbiology. 85 (2): 345- ... sRNA BM-sr0117 from Brucella melitensis was identified and shown to be bound to and cleaved by Bm-RNase III. AbcR and AbcR2 ( ... In Brucella melitensis eight novel sRNA genes were identified using bioinformatic and experimental approach. One of them ...

https://en.wikipedia.org/wiki/Brucella_sRNA

... detection of antibody to Brucella abortus". Methods. 22 (1): 71-6. doi:10.1006/meth.2000.1038. PMID 11020320. Jameson D (2003 ...

https://en.wikipedia.org/wiki/Fluorescence_polarization_immunoassay

Gor D, Mayfield JE (February 1992). "Cloning and nucleotide sequence of the Brucella abortus groE operon". Biochimica et ...

https://en.wikipedia.org/wiki/Chaperonin

Pei J, Ficht TA (January 2004). "Brucella abortus rough mutants are cytopathic for macrophages in culture". Infection and ... Ugalde JE, Czibener C, Feldman MF, Ugalde RA (October 2000). "Identification and characterization of the Brucella abortus ... Ugalde JE, Comerci DJ, Leguizamón MS, Ugalde RA (November 2003). "Evaluation of Brucella abortus phosphoglucomutase (pgm) ... "Establishment of systemic Brucella melitensis infection through the digestive tract requires urease, the type IV secretion ...

https://en.wikipedia.org/wiki/Alpha-D-phosphohexomutase_superfamily

Groocock, C.M.; Staak, C. (1969). "The isolation of Brucella abortus from a waterbuck (Kobus ellipsiprymnus)". The Veterinary ...

https://en.wikipedia.org/wiki/Waterbuck

Brucellosis is caused by different biotypes of Brucella abortus and B. melitensis. Other internal parasites include Fasciola ...

https://en.wikipedia.org/wiki/Dromedary

Currently, all cattle of ages 3-8 months must receive the Brucella abortus strain 19 vaccine. Australia is free of cattle ... Brucella species survive well in aerosols and resist drying. Brucella and all other remaining biological weapons in the U.S. ... Four species infect humans: B. abortus, B. canis, B. melitensis, and B. suis. B. abortus is less virulent than B. melitensis ... "An ecological perspective on Brucella abortus in the western United States" (PDF). Revue Scientifique et Technique. 32 (1): 79- ...

https://en.wikipedia.org/wiki/Brucellosis

On the other hand, ALOX5 gene knockout mice demonstrate an enhanced resistance and lessened pathology to Brucella abortus ... "5-Lipoxygenase negatively regulates Th1 response during Brucella abortus infection in mice". Infection and Immunity. 83 (3): ...

https://en.wikipedia.org/wiki/Arachidonate_5-lipoxygenase

"Successful Medical Treatment of Prosthetic Mitral Valve Endocarditis Caused by Brucella abortus". Korean Circulation Journal. ...

https://en.wikipedia.org/wiki/Remittent_fever

Danish veterinarian Bernhard Bang isolates Brucella abortus as the agent of Brucellosis. L. Emmett Holt publishes the standard ...

https://en.wikipedia.org/wiki/1897_in_science

GINOZA HS, ALTENBERN RA (1955). "The pantothenate-synthesizing enzyme in cell-free extracts of Brucella abortus, strain 19". ...

https://en.wikipedia.org/wiki/Pantoate—beta-alanine_ligase

"Mur regulates the gene encoding the manganese transporter MntH in Brucella abortus 2308". Journal of Bacteriology. 194 (3): 561 ...

https://en.wikipedia.org/wiki/Ferric_uptake_regulator_family

He discovered Brucella abortus in 1897, which came to be known as Bang's bacillus. Bang's bacillus was the cause of the ... "Bacillus abortus" by the American microbiologist Alice Evans]", Zeitschrift für ärztliche Fortbildung, vol. 82, no. 8, pp. 381- ...

https://en.wikipedia.org/wiki/Bernhard_Bang

"The Brucella abortus CcrM DNA Methyltransferase Is Essential for Viability, and Its Overexpression Attenuates Intracellular ... the plant symbiont Sinorhizobium meliloti and in the human pathogen Brucella abortus. Also CcrM gene has proven to be essential ...

https://en.wikipedia.org/wiki/Cell_cycle_regulated_Methyltransferase

Aside from these bacteria, PPIB has been identified in Brucella abortus, Mycobacterium tuberculosis, Bacillus subtilis and ... "Intracellularly Induced Cyclophilins Play an Important Role in Stress Adaptation and Virulence of Brucella abortus". Infection ...

https://en.wikipedia.org/wiki/PPIB

He was chairman of the committee on Brucella abortus infection and on Johne's disease (Paratuberculosis). He also chaired the ...

https://en.wikipedia.org/wiki/Joseph_Arthur_Arkwright

... abortus, Brucella canis, Brucella neotomae, Brucella ovis, and Brucella suis are all synonyms of Brucella melitensis. ... Brucella abortus A13334, 3,401 ORFs Brucella canis ATCC 23365, 3,408 ORFs Brucella melitensis 16M, 3,279 ORFs Brucella microti ... 3,193 ORFs Brucella pinnipedialis B2/94, 3,505 ORFs Brucella suis 1330, 3,408 ORFs Genome data for these and other Brucella ... July 2014). "G1-arrested newborn cells are the predominant infectious form of the pathogen Brucella abortus". Nature ...

https://en.wikipedia.org/wiki/Brucella

"Immune Responses and Safety after Dart or Booster Vaccination of Bison with Brucella abortus Strain RB51". American Society for ...

https://en.wikipedia.org/wiki/Dart_gun

Beh KJ (1976). "Immunoglobulin class specificity of non-agglutinating antibody produced in cattle following Brucella abortus 45 ...

https://en.wikipedia.org/wiki/EEF1A2

"Brucella abortus Transits through the Autophagic Pathway and Replicates in the Endoplasmic Reticulum of Nonprofessional ...

https://en.wikipedia.org/wiki/Gisou_van_der_Goot

Pouvoir inhibiteur de ce produit vis-à-vis du bacille typhique, du colibacille, de Brucella abortus etc". Comptes Rendus de ... and Brucea abortus. Clitocine has also been shown to promote apoptosis (cell death) in human cervical cancer cells in vitro ( ...

https://en.wikipedia.org/wiki/Leucopaxillus_giganteus

"Molecular epidemiology of Brucella abortus isolates from cattle, elk, and bison in the United States, 1998 to 2011". Appl. ...

https://en.wikipedia.org/wiki/Bison_hunting

Brucella abortus (Q57B94), Brucella suis (Q8FYS0) and Brucella melitensis (Q8YJ29). The biochemical mechanism of proline ...

https://en.wikipedia.org/wiki/Proline_racemase

Liposomised recombinant ribosomal L7/L12 protein protects BALB/c mice against Brucella abortus 544 infection. Vaccine. 2007, 4; ... He had successfully expressed L7/L12 ribosomal protein, SOD-IL-18 fusion protein of Brucella spp. and trypanothione reductase ... entrapped DNA vaccine co-expressing Cu-Zn superoxide dismutase and IL-18 confers protection against Brucella abortus". Microbes ... the protective efficacy of liposomes encapsulated recombinant Cu-Zn superoxide dismutase protein against Brucella abortus. ...

https://en.wikipedia.org/wiki/Owais_Mohammad

Some bacteria like Brucella abortus, Moraxella catarrhalis and Streptococcus pneumoniae have developed resistance towards ...

https://en.wikipedia.org/wiki/Cefprozil

The Brucella abortus (rough LPS Brucella) vaccine, developed for bovine brucellosis and licensed by the USDA Animal Plant ... of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella ... Brucella suis and other Brucella species (B. melitensis, B. abortus, B. ovis, B. canis) are recognized as potential ... "Brucella abortus cyclic beta-1,2-glucan mutants have reduced virulence in mice and are defective in intracellular replication ...

https://en.wikipedia.org/wiki/Brucella_suis

Antitumor process using a Brucella abortus preparation, retrieved 2016-01-26 Selected Patents Dowling, Patricia W.; Youngner, ... antitumor processes of Brucella, and numerous contributions to cold adapted influenza virus. Youngner met and married his first ...

https://en.wikipedia.org/wiki/Julius_Youngner

1 Brucella abortus bv. 1 str. 9-941 Brucella abortus bv. 2 Brucella abortus bv. 3 Brucella abortus bv. 4 Brucella melitensis ... a synonym for Brucella abortus Brucella melitensis biovar Abortus 2308, a synonym for Brucella abortus 2308 Brucella abortus bv ... a synonym for Brucella canis Brucella melitensis biovar Melitensis Brucella melitensis bv. 1 Brucella melitensis bv. 2 Brucella ... 3 Brucella melitensis biovar Neotomae, synonym for Brucella neotomae Brucella melitensis biovar Ovis, synonym for Brucella ovis ...

https://en.wikipedia.org/wiki/Biovar

... of the deceased fetus causes necrosis of the placenta and placental lesions are not easily distinguished from Brucella abortus ... stomach contents or tissue of abortuses. Samples should be immediately transported to the lab and enrichment needs to be ...

https://en.wikipedia.org/wiki/Campylobacter_fetus

Negrón, María E.; Kharod, Grishma A.; Bower, William A.; Walke, Henry (2019). "Notes from the Field: Human Brucella abortus ...

https://en.wikipedia.org/wiki/List_of_vaccine_topics

Elimination of Brucella abortus from infected domestic (Bos taurus) and wild (Bos gaurus) cattle and buffalo (Syncerus caffer) ...

https://en.wikipedia.org/wiki/Morné_de_la_Rey

... as well as in a broad spectrum of Brucella species (B. ovis, B. canis, B. abortus and B. microtis, and several biovars of B. ... abortus, B. microtis, and several biobars of B. melitensis), Brucella anthropi, the Mesorhizobium species loti, M. ciceri and M ... viciae 3841 strain, and the Agrobacterium species A. vitis,A. tumefaciens, A. radiobacter and A. H13, Brucella species (B. ovis ... Partial synteny of the αr45 genomic regions was observed in the Mesorhizobium and Brucella species where instead of aLysR ...

https://en.wikipedia.org/wiki/Αr45_RNA

It can be caused by infection from Actinomyces bovis or Brucella abortus organisms, but may also occur due to parasite ... Because of modern efforts to reduce the incidence of brucellosis in livestock, horses are less exposed to the Brucella abortus ...

https://en.wikipedia.org/wiki/Poll_evil

... may refer to: Bang's bacillus, Brucella abortus, a bacterium that causes abortion in hoofed animals and undulant fever ...

https://en.wikipedia.org/wiki/Bang's

... as well as in a broad spectrum of Brucella species (B. ovis, B. canis, B. abortus and B. microtis, and several biovars of B. ... abortus, B. microtis, and several biobars of B. melitensis), Brucella anthropi and the Mesorhizobum species loti, M. ciceri and ... The second group is formed by the first copy in the Chromosome I in the Brucellas genomes that share the gene upstream coding ... The same context was found for the second copy in the chromosome II of Brucella anthropi (Oar14CII2) and the second copy in ...

https://en.wikipedia.org/wiki/Αr14_RNA

2005). "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella ... 2002). "The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts". Proc. Natl ... 2005). "The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies ... 2002). "The genome sequence of the facultative intracellular pathogen Brucella melitensis". Proc. Natl. Acad. Sci. U.S.A. 99 (1 ...

https://en.wikipedia.org/wiki/List_of_sequenced_bacterial_genomes

Danish veterinarian who discovered Brucella abortus Denis Barberet (1714-1770) - French bibliographer and author Harold William ...

https://en.wikipedia.org/wiki/List_of_veterinarians

Studies on the bactericidal action of bovine whole blood and serum towards Brucella abortus and Brucella suis. J. Infect. Dis. ...

https://en.wikipedia.org/wiki/Malcolm_Robert_Irwin

For example, Agrobacterium tumefaciens is a plant pathogen, Brucella abortus is an animal pathogen, and Sinorhizobium meliloti ...

https://en.wikipedia.org/wiki/Caulobacter_crescentus

A new type of vaccine Charles Pilet and Marc Bonneau are creating a new type of vaccine from a strain of Brucella abortus made ... Non specific stimulation by inactivated or ultrasonicated Brucella abortus », Cancer Res., 47, 1974, p. 294-301 T.Neway, F, ... vaccine control method The study of several mouse lines showed the sensitivity of some of these lines to Brucella abortus, ... This type of vaccine also confirmed the essentially cellular nature of brucella immunity and the passive role of antibodies. A ...

https://en.wikipedia.org/wiki/Charles_Pilet

Human Brucella abortus RB51 Infections Caused by Consumption of Unpasteurized Domestic Dairy Products - United States, 2017- ...

https://en.wikipedia.org/wiki/List_of_infectious_diseases

... as well as in a broad spectrum of Brucella species (B. ovis, B. canis, B. abortus and B. microtis, and several biovars of B. ... abortus, B. microtis, and several biobars of B. melitensis), Brucella anthropi and the Mesorhizobum species M. loti, M. ciceri ... A special case is the Brucella group, where primary automatic annotation over their genomes identified ORFs smaller than 30 aa ... but lower bit-scores and are encoded by Brucella species (B. ovis, B. canis, B. ...

https://en.wikipedia.org/wiki/Αr9_RNA

... On May 26-27, 1997, nine persons (a farmer, four veterinary ... Experimental infection of pregnant cattle with the vaccine candidate Brucella abortus strain RB51: pathologic, bacteriologic, ... and a necropsy on a stillborn calf that died because of Brucella abortus infection. The infection was confirmed by isolation of ... vaccinated with Brucella abortus strain RB51. J Vet Diagn Invest 1997;9:363-7. ...

https://www.cdc.gov/mmwR/preview/mmwrhtml/00051495.htm

... MMWR 47(09);172-175 Publication date: 03/13/1998. Table of ... Experimental infection of pregnant cattle with the vaccine candidate Brucella abortus strain RB51: pathologic, bacteriologic, ... and a necropsy on a stillborn calf that died because of Brucella abortus infection. The infection was confirmed by isolation of ... a stable rough strain of Brucella abortus. Vet Microbiol 1991;28:171-88. * Cheville NF, Jensen AE, Halling SM, et al. Bacterial ...

https://wonder.cdc.gov/wonder/prevguid/m0051495/m0051495.asp

... one in the core oligosaccharide from rough Brucella LPS (R), and one in lipid A (LA). From 46 different hybridomas secreting ... Sera from Brucella abortus-infected and -vaccinated bovines recognized four lipopolysaccharide (LPS) determinants: two in the O ... New Features in the Lipid A Structure of Brucella suis and Brucella abortus Lipopolysaccharide. Casabuono AC, Czibener C, Del ... Immunochemical identification of Brucella abortus lipopolysaccharide epitopes N Rojas 1 , E Freer, A Weintraub, M Ramirez, S ...

https://pubmed.ncbi.nlm.nih.gov/7496947

BRUCELLA ABORTUS (UNII: 492LCM0TUL) (BRUCELLA ABORTUS - UNII:492LCM0TUL) BRUCELLA ABORTUS. 16 [hp_X] in 1 mL. ... Aloe 6X, Hydrastis Canadensis 6X, Allium Sativum 12X, Anthracinum 16X, 30X, Bacillus Tetani 16X, 30X, Brucella Abortus 16X, 30X ... Label: BACTEX (aloe, hydrastis canadensis, allium sativum, anthracinum, bacillus tetani (clostridium tetani), brucella abortus ... BACTEX (aloe, hydrastis canadensis, allium sativum, anthracinum, bacillus tetani (clostridium tetani), brucella abortus, ...

https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c6055c02-a365-4adf-9d3a-47d717c4c93d&version=1

Brucellosis is a zoonotic infection caused by the bacterial genus Brucella. The bacteria are transmitted from animals to humans ... Of the 4 Brucella species known to cause disease in humans (B abortus, B melitensis, B canis, B suis), B melitensis is thought ... Celebi G, Külah C, Kiliç S, Ustündag G. Asymptomatic Brucella bacteraemia and isolation of Brucella melitensis biovar 3 from ... B abortus is more widely distributed throughout the world than B melitensis is, but it is less pathogenic for both animals and ...

https://www.medscape.com/answers/213430-36538/how-does-the-incidence-of-brucellosis-vary-by-age-in-different-geographic-locations

https://www.medscape.com/answers/213430-36518/what-percentage-of-brucellae-are-able-to-survive-after-ingestion

Brucella abortus. Influenza. Brugia malayi. Listeria monocytogenes. Dengue. Loa loa. Parvovirus. Onchocerca volvulus. ...

https://emedicine.medscape.com/article/240229-medication

Brucella abortus. *Brucella melitensis. *Botulinum neurotoxin-producing species of Clostridium. *Venezuelan equine encephalitis ...

https://www.niaid.nih.gov/research/rutgers-regional-biocontainment-lab

Notes from the Field: Brucella abortus RB51 Infections Associated with Consumption of Raw Milk from Pennsylvania - 2017 and ...

https://pesquisa.bvsalud.org/saudepublica/resource/pt/mdl-32298248

Notes from the Field: Brucella abortus vaccine strain RB51 infection and exposures associated with raw milk consumption - Wise ... a stable rough strain of Brucella abortus. Vet Microbiol. 1991 Jul;28(2):171-88. ... Brucella strain RB51 is a live-attenuated cattle vaccine strain, which can be shed in milk and can cause infections in humans. ... This investigation is associated with the third known case of brucellosis from Brucella RB51 due to raw milk acquired in the U. ...

https://emergency.cdc.gov/han/han00417.asp

Brucella abortus 2 * Burkholderia cepacia 4 * Burkholderia pseudomallei 5 * Cannabinoids 2 * Cannabis 1 ...

https://stacks.cdc.gov/cbrowse?pid=cdc%3A24915&parentId=cdc%3A24915&start=120

https://www.emergency.cdc.gov/han/HAN00417.asp

Shapouri, R and Rahnema, M. Evaluation of antimicrobial effect of hops extracts on intramacrophages Brucella abortus and B. ...

https://medlineplus.gov/spanish/druginfo/natural/856.html

Brucella abortus-activated microglia induce neuronal death through primary phagocytosis.. Rodríguez AM; Delpino MV; Miraglia MC ...

https://pubmedhh.nlm.nih.gov/biomarkers/search.php?id=25421817&mod=related&page=1&outid=&proj=

Vergleichende Untersuchungen über den Nachweis von Brucella abortus in Einzel- und Gruppenmilchproben [Giessen]. ... Vergleichende Untersuchungen zum Nachweis von Bakterium Abortus Bang in Milch [Giessen]. Subject(s):. Milk bacteria [ incl. ...

https://indexcat.nlm.nih.gov/vivisimo/cgi-bin/query-meta?&v:project=indexcat&v:sources=indexcat&sortby=Title&binning-state=pt%3d%3dDissertation%0aserieNumber%3d%3dSeries%204,%201936-1948,%201955%0aserieVolume%3d%3dVolume%20011%0aseriePage%3d%3dPage%201232&

abortus. Since Orpen did not give the data when he first obtained brucellae from a patient, it is questionable whether his ... Limited knowledge of brucellae at that time was responsible for Dr. Smiths confusion. In 1914 Traum reported that Br. abortus ... now designated Brucella abortus. For several years it had been known to exist in the udder of infected cows, having been ... abortus in cows milk, it would seem remarkable that we do not have a disease resembling Malta fever in this country." And I ...

https://history.nih.gov/x/woDi

Brucella B03.660.050.070.100.100 Brucella abortus B03.660.050.070.100.150 Brucella canis B03.660.050.070.100.500 Brucella ... Brucella B03.440.400.425.215.500.100 Brucella abortus B03.440.400.425.215.500.150 Brucella canis B03.440.400.425.215.500.500 ... Brucella melitensis B03.440.400.425.215.500.625 Brucella ovis B03.440.400.425.215.500.750 Brucella suis B03.440.400.425.251 ... melitensis B03.660.050.070.100.625 Brucella ovis B03.660.050.070.100.750 Brucella suis B03.660.050.070.700 Ochrobactrum B03.660 ...

https://www.nlm.nih.gov/mesh/2019/download/2019New_Mesh_Tree_Hierarchy.txt

Select Pseudomonas aeruginosa PAO1, Pseudomonas aeruginosa PA7, and Brucella abortus bv. 1 str. 9-941. Click on the OK button ...

https://nihlibrary.ors.nih.gov/bioinfo/MGA/Problem2.html

Brucella abortus (organism) Code System Concept Status. Published. Code System Preferred Concept Name. Brucella abortus ( ...

https://phinvads.cdc.gov/vads/ViewValueSetConcept.action?id=FBC12380-9DAB-4807-ADF4-ED2687024B8A

Brucella [B03.440.400.425.215.500] * Brucella abortus [B03.440.400.425.215.500.100] * Brucella canis [B03.440.400.425.215.500. ... Brucella abortus Preferred Concept UI. M0002987. Registry Number. txid235. Scope Note. A species of the genus BRUCELLA whose ... Bacterium abortus Brucella melitensis biovar abortus Registry Number. txid235. Date Established. 1966/01/01. Date of Entry. ... Brucella abortus Preferred Term Term UI T005699. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1966). ...

https://meshb-prev.nlm.nih.gov/record/ui?ui=D002003

https://meshb.nlm.nih.gov/record/ui?ui=D002003

... usually Brucella abortus (cattle), Brucella melitensis, Brucella ovis (sheep, goats), Brucella suis (pigs), or rarely Brucella ... Brucellosis is an infection with a bacterium of one of the Brucella species, ...

https://reference.medscape.com/article/1169489-overview

None of the exposed persons reported having previously had brucellosis or being unintentionally inoculated with Brucella vaccine. (cdc.gov)
Editorial Note: Brucellosis, also known as 'undulant fever' or 'Bangs disease,' is a systemic infection caused by Brucella sp. (cdc.gov)
During a severe outbreak of brucellosis in buffaloes, two animal attendants and one Veterinarian contracted Brucella abortus infection. (nih.gov)
An enzyme immunoassay for bovine brucellosis using a monoclonal antibody specific for field strains of Brucella abortus. (nih.gov)
Brucellosis is an endemic disease in Zimbabwe caused by the genus Brucella . (ojvr.org)
The aim of this study was to investigate Brucella species in brucellosis seropositive cattle in the Chiredzi district with access to GNP using isolation and identification. (ojvr.org)
The results showed that the bacterial ghost vaccine of Brucella represents a more safe and efficient vaccine for brucellosis . (bvsalud.org)
This investigation is associated with the third known case of brucellosis from Brucella RB51 due to raw milk acquired in the U.S., since August 2017. (cdc.gov)
When ordering blood cultures to diagnose brucellosis, please advise the laboratory that blood culture may grow Brucella and that appropriate laboratory containment and precautions should be observed. (cdc.gov)
Brucellosis ( Brucella spp. (nih.gov)
The bacterium is known as Brucella abortus , or brucellosis. (nathab.com)
Detection of antibodies to Brucella abortus and Brucella suis, the causative agents of brucellosis, using buffered acidified plate antigen (BAPA). (tamu.edu)
Detection of antibodies to Brucella abortus and Brucella suis, the causative agents of brucellosis, by card agglutination. (tamu.edu)

small Gram-negative coccobacilli that can infect cattle (infection with B. abortus), goats and sheep (B. melitensis), pigs (B. suis), and dogs (B. canis). (cdc.gov)
The Brucella species generally considered pathogenic for humans, in decreasing order of virulence, are Brucella melitensis , Brucella suis and B. abortus (Baldwin & Goenka 2006). (ojvr.org)
The six classical species are B. abortus in cattle, B. melitensis in goats, B. suis in pigs, B. canis in dogs, B. ovis in sheep, and B. neotomae in rat [ 3 - 5 ]. (hindawi.com)
Brucella abortus , B. melitensis , B. suis , and to some extent, B. canis , are responsible for the majority of infections in animals and humans [ 2 , 5 ]. (hindawi.com)

1996) identified B. abortus biovar 1 cultures from aborted foetuses. (ojvr.org)
Various polymerase chain reaction (PCR) assays are available for differentiating Brucella at the genus, species and/or biovar level. (ojvr.org)

The National Animal Disease Center, U.S. Department of Agriculture (USDA), identified the B. abortus isolate from the calf as the RB51 vaccine strain. (cdc.gov)
The vaccine had caused active B. abortus infection because the 14-month-old heifer delivering the calf was not known to be pregnant when she was vaccinated with RB51 at approximately 8 months of age, which was within the specified age range for vaccination. (cdc.gov)
Evidence that intrauterine infection was caused by the RB51 vaccine strain, and not by field strains of B. abortus or by S19, included immunohistochemical staining specific for RB51 (negative for S19), RB51-specific titer of greater than 1:10,000 on experimental dot-blot assay measuring antibody to RB51, and RB51-specific DNA sequences identified by polymerase chain reaction (PCR). (cdc.gov)
The New York State Department of Health and Pennsylvania Department of Health are investigating Brucella RB51 exposures that may be connected to consuming raw (unpasteurized) milk from Miller's Biodiversity Farm in Quarryville, Pennsylvania. (cdc.gov)
Milk samples from the dairy tested positive for Brucella strain RB51. (cdc.gov)
Brucella strain RB51 is a live-attenuated cattle vaccine strain, which can be shed in milk and can cause infections in humans. (cdc.gov)
Brucella abortus vaccine strain RB51 infection and exposures associated with raw milk consumption - Wise County, Texas, 2017. (cdc.gov)

Detection of Brucella spp. (tamu.edu)

Factors Responsible for the Differential Growth of Brucella Abortus in Bovine Trophoblasts. (lsu.edu)
The interactions of bovine chorionic membrane explants (CAMs) as well as three different bovine trophoblastic cell lines with Brucella abortus were evaluated. (lsu.edu)
Three trophoblastic cell lines derived from bovine placentas of differing gestational stages were used to study the differential replication of B. abortus. (lsu.edu)
Brucella abortus rapidly replicate within the trophoblastic cell lines derived from 5 and 8-month-old-bovine placentas but grew slowly within trophoblastic cells derived from embryonic bovine placenta. (lsu.edu)

Lorne Labs also manufacture and supply Rose Bengal staining tests which is a simple and popular way to detect anti-Brucella antibodies in human and animal serum. (lornelabs.com)
Rose Bengal is a slide agglutination test for the qualitative and semi-quantitative detection of anti-Brucella antibodies in human and animal serum. (lornelabs.com)

The conjugative transfer of plasmids between Gram-negative bacteria is mediated by type IV secretion system (T4SS) and many pathogens such as Helicobacter pylori , Bartonella and Brucella species use this strategy for the transfer of virulence factors into mammalian cells. (nature.com)
It is caused by different species of the genus brucella [ 2 ]. (hindawi.com)
Brucella species are facultative intracellular pathogens that can survive, multiply, and persist within phagocytic cells of the host resulting in lifetime carriage of the organism [ 6 ]. (hindawi.com)
A species of the genus BRUCELLA whose natural hosts are cattle and other bovidae. (nih.gov)

On May 26-27, 1997, nine persons (a farmer, four veterinary clinicians, and four veterinary students) in Manhattan, Kansas, participated in an attempted vaginal delivery, a cesarean delivery, and a necropsy on a stillborn calf that died because of Brucella abortus infection. (cdc.gov)
The infection was confirmed by isolation of B. abortus from placental and fetal lung tissue cultures. (cdc.gov)
Brucella abortus infection in indigenous Korean dogs. (nih.gov)
In addition, prostanoid and hormone production by the trophoblastic cells after infection with B. abortus was measured. (lsu.edu)

In the pathogen Brucella abortus, smooth lipopolysaccharide containing the O-antigen is required for virulence. (unamur.be)
Moreover, we identify the main O-antigen ligase of Brucella spp. (unamur.be)
The reagents of the kit are stained to enhance the reading of the agglutination tests, making the febrile antigen kits the most efficient test kit when dealing with Salmonellae, Brucellae or Richettsiae type infections. (lornelabs.com)

Serological evidence of Brucella abortus prevalence in Punjab province, Pakistan--a cross-sectional study. (nih.gov)

Brucella seroprevalence was recently reported to be high in the wildlife-livestock interface in the Chiredzi district and the neighbouring Gonarezhou National Park (GNP) in Zimbabwe, and higher amongst communal cattle with an abortion history and access to grazing in GNP than amongst communal cattle with no abortion history or access to grazing in GNP. (ojvr.org)
Our results confirmed that B. abortus is present in cattle on communal farms in the Chiredzi district in Zimbabwe and might cause cattle abortions. (ojvr.org)

In the second phase, Brucella toethanol (2-MET) in the assay disulfide spp. (who.int)

In pregnant patients, Brucella infections can be associated with miscarriage. (cdc.gov)

10. Persisting fever in a patient with brucella endocarditis: occult splenic abscess. (nih.gov)

Brucella abortus was cultured and identified from blood and milk collected from seropositive cows in both communal areas. (ojvr.org)
Most Brucella cultures have been isolated from aborted foetuses, milk, hygroma fluid, or lymph nodes from infected animals. (ojvr.org)
2009) isolated primarily B. abortus bv 1 and to a lesser extent B. abortus bv 2 from aborted foetuses and milk samples from infected herds in Zimbabwe. (ojvr.org)
Milk serology Agglutinin: Brucella [ Abbrev. (nih.gov)

The ability of B. abortus to infect and grow within the cells of these CAMs and within these cell lines was measured. (lsu.edu)

Proteomic and Antibody Profiles Reveal Antigenic Composition and Signatures of Bacterial Ghost Vaccine of Brucella abortus A19. (bvsalud.org)
We developed and evaluated a new bacterial ghost vaccine of Brucella abortus A19 by a new double inactivation method . (bvsalud.org)

abortus was demonstrated in the sera of these sick individuals. (nih.gov)

The Brucella- specific 16-23S intergenic spacer (ITS) PCR and multiplex AMOS-PCR assays verified the identification of the cultures. (ojvr.org)

Details for: Elaboraci'on y normalizaci'on de la vacuna brucella abortus, cepa 19. (who.int)

These hormones and prostanoids were individually added to the standard tissue culture media to determine the effects of these compounds on B. abortus growth. (lsu.edu)

Internalization of B. abortus within the cells of CAMs derived from placentas from both 3-month-gravid cows and 7-month-gravid cows was similar. (lsu.edu)

Progesterone during the first 8 hours of the culture increased the replication rate of B. abortus in the two cell lines. (lsu.edu)

small Gram-negative coccobacilli that can infect cattle (infection with B. abortus), goats and sheep (B. melitensis), pigs (B. suis), and dogs (B. canis). (cdc.gov)
B melitensis, B abortus, and B suis have been completely sequenced, and these sequencing data will help improve our understanding of the pathogenesis and the manifestations of this complex disease. (medscape.com)

The National Animal Disease Center, U.S. Department of Agriculture (USDA), identified the B. abortus isolate from the calf as the RB51 vaccine strain. (cdc.gov)
Evidence that intrauterine infection was caused by the RB51 vaccine strain, and not by field strains of B. abortus or by S19, included immunohistochemical staining specific for RB51 (negative for S19), RB51-specific titer of greater than 1:10,000 on experimental dot-blot assay measuring antibody to RB51, and RB51-specific DNA sequences identified by polymerase chain reaction (PCR). (cdc.gov)
Brucella strain RB51 is a live-attenuated cattle vaccine strain, which can be shed in milk and can cause infections in humans. (cdc.gov)
Brucella abortus vaccine strain RB51 infection and exposures associated with raw milk consumption - Wise County, Texas, 2017. (cdc.gov)

Select Pseudomonas aeruginosa PAO1, Pseudomonas aeruginosa PA7, and Brucella abortus bv. (nih.gov)

Brucella organisms, which are small aerobic intracellular coccobacilli, localize in the reproductive organs of host animals, causing abortions and sterility. (medscape.com)
Brucellae are aerobic gram-negative coccobacilli that possess a unique ability to invade both phagocytic and nonphagocytic cells and to survive in the intracellular environment by finding ways to avoid the immune system. (medscape.com)

Sera from Brucella abortus-infected and -vaccinated bovines recognized four lipopolysaccharide (LPS) determinants: two in the O-polysaccharide (A and C), one in the core oligosaccharide from rough Brucella LPS (R), and one in lipid A (LA). From 46 different hybridomas secreting monoclonal antibodies (MAbs) against various LPS moieties, 9 different specificities were identified. (nih.gov)
Two epitopes were found in the core oligosaccharide (R1 and R2) of rough Brucella LPS. (nih.gov)
LPS preparations from smooth brucellae had small amounts of rough-type LPS. (nih.gov)
Although LPS from rough brucellae did not show smooth-type LPS in western blots (immunoblots), two hybridomas generated from mice immunized with rough B. abortus produced antibodies against smooth B. abortus LPS. (nih.gov)
a stable rough strain of Brucella abortus . (cdc.gov)

Brucella can gain entry into the human body through breaks in the skin, mucous membranes, conjunctivae, and respiratory and gastrointestinal (GI) tracts. (medscape.com)

Anatomy2

Organisms13

Diseases4

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Phenomena and Processes1

Health Care1

Modulation of endocytosis in nuclear factor IL-6(-/-) macrophages is responsible for a high susceptibility to intracellular bacterial infection. (1/780)

Immunity to Brucella in mice vaccinated with a fraction (F8) or a killed vaccine (H38) with or without adjuvant. Level and duration of immunity in relation to dose of vaccine, recall injection and age of mice. (2/780)

Murine macrophage-lymphocyte interactions: scanning electron microscopic study. (3/780)

Plaque-forming cells in mice after experimental infection with Brucella abortus. (4/780)

Antibody response to antigens distinct from smooth lipopolysaccharide complex in Brucella infection. (5/780)

The siderophore 2,3-dihydroxybenzoic acid is not required for virulence of Brucella abortus in BALB/c mice. (6/780)

Structure and function prediction of the Brucella abortus P39 protein by comparative modeling with marginal sequence similarities. (7/780)

Comparison of sensitivity and specificity of purified lymphocyte and whole-blood in vitro lymphocyte stimulation assays in detection of Brucella abortus infection in cattle. (8/780)

Brucella abortus

Brucella

Brucellosis

Brucellosis, Bovine

Brucella Vaccine

Brucella melitensis

Brucella ovis

Brucella canis

Abortion, Veterinary

Antibodies, Bacterial

Agglutination Tests

Cattle

Erythritol

Chlamydophila

Bison

Antigens, Bacterial

Brucella suis

Complement Fixation Tests

Ochrobactrum anthropi

Bacterial Vaccines

Mice, Inbred BALB C

Bacterial Proteins

Virulence

Spleen

Rose Bengal

DNA, Bacterial

Macrophages

Buffaloes

Lipopolysaccharides

Bacterial Outer Membrane Proteins

Vaccination

Sheep Diseases

Hydroxybenzoates

Goats

Modulation of endocytosis in nuclear factor IL-6(-/-) macrophages is responsible for a high susceptibility to intracellular bacterial infection. (1/780)

Immunity to Brucella in mice vaccinated with a fraction (F8) or a killed vaccine (H38) with or without adjuvant. Level and duration of immunity in relation to dose of vaccine, recall injection and age of mice. (2/780)

Murine macrophage-lymphocyte interactions: scanning electron microscopic study. (3/780)

Plaque-forming cells in mice after experimental infection with Brucella abortus. (4/780)

Antibody response to antigens distinct from smooth lipopolysaccharide complex in Brucella infection. (5/780)

The siderophore 2,3-dihydroxybenzoic acid is not required for virulence of Brucella abortus in BALB/c mice. (6/780)

Structure and function prediction of the Brucella abortus P39 protein by comparative modeling with marginal sequence similarities. (7/780)

Comparison of sensitivity and specificity of purified lymphocyte and whole-blood in vitro lymphocyte stimulation assays in detection of Brucella abortus infection in cattle. (8/780)

Brucella abortus

Alanine racemase

Brian Sinclair (veterinary surgeon)

Rose Payne

Alanine-oxo-acid transaminase

Brucella sRNA

Fluorescence polarization immunoassay

Chaperonin

Alpha-D-phosphohexomutase superfamily

Waterbuck

Dromedary

Brucellosis

Arachidonate 5-lipoxygenase

Remittent fever

1897 in science

Pantoate-beta-alanine ligase

Ferric uptake regulator family

Bernhard Bang

Cell cycle regulated Methyltransferase

PPIB

Joseph Arthur Arkwright

Brucella

Dart gun

EEF1A2

Gisou van der Goot

Leucopaxillus giganteus

Bison hunting

Proline racemase

Owais Mohammad

Cefprozil

Brucella suis

Julius Youngner

Biovar

Campylobacter fetus

List of vaccine topics

Morné de la Rey

Αr45 RNA

Poll evil