Brucea: A plant genus of the family SIMAROUBACEAE. Members contain bruceosides and bruceanols (quassinoids). The astringent seeds have been used to treat dysentery in southeastern Asia.Quassins: A group of degraded TRITERPENES which have lost ten carbons (8 from the side chain, C17, and one from C4) so have C20 skeletons which could be misinterpreted as DITERPENES. They especially occur in plants of the SIMAROUBACEAE family.Glaucarubin: (1 beta,2 alpha,11 beta,12 alpha,15 beta(S))-11,20-Epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)picras-3-en-16-one. A quassinoid (Simaroubolide) from Simaruba glauca, a tropical shrub. It has been used as an antiamebic agent and is found to be cytotoxic. It may be of use in cancer chemotherapy.Amebicides: Agents which are destructive to amebae, especially the parasitic species causing AMEBIASIS in man and animal.Flavonolignans: Heterodimers of FLAVONOIDS bound to LIGNANS.Coix: A plant genus of the family POACEAE. The seed is used in folk medicine (DRUGS, CHINESE HERBAL).Societies, Pharmaceutical: Societies whose membership is limited to pharmacists.Education, Pharmacy, Graduate: Educational programs for pharmacists who have a bachelor's degree or a Doctor of Pharmacy degree entering a specific field of pharmacy. They may lead to an advanced degree.Drug Industry: That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.Education, Pharmacy: Formal instruction, learning, or training in the preparation, dispensing, and proper utilization of drugs in the field of medicine.Technology, Pharmaceutical: The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.Students, Pharmacy: Individuals enrolled in a school of pharmacy or a formal educational program leading to a degree in pharmacy.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Tropical Climate: A climate which is typical of equatorial and tropical regions, i.e., one with continually high temperatures with considerable precipitation, at least during part of the year. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Ethnobotany: The study of plant lore and agricultural customs of a people. In the fields of ETHNOMEDICINE and ETHNOPHARMACOLOGY, the emphasis is on traditional medicine and the existence and medicinal uses of PLANTS and PLANT EXTRACTS and their constituents, both historically and in modern times.Plants, Genetically Modified: PLANTS, or their progeny, whose GENOME has been altered by GENETIC ENGINEERING.Search Engine: Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.Plant Leaves: Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)Plant Proteins: Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.Information Storage and Retrieval: Organized activities related to the storage, location, search, and retrieval of information.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.BooksPublishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.MEDLINE: The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).Serial Publications: Publications in any medium issued in successive parts bearing numerical or chronological designations and intended to be continued indefinitely. (ALA Glossary of Library and Information Science, 1983, p203)Biological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Chiropractic: An occupational discipline founded by D.D. Palmer in the 1890's based on the relationship of the spine to health and disease.Cellular Phone: Analog or digital communications device in which the user has a wireless connection from a telephone to a nearby transmitter. It is termed cellular because the service area is divided into multiple "cells." As the user moves from one cell area to another, the call is transferred to the local transmitter.Manipulation, Chiropractic: Procedures used by chiropractors to treat neuromusculoskeletal complaints.Physical Therapists: Persons trained in PHYSICAL THERAPY SPECIALTY to make use of PHYSICAL THERAPY MODALITIES to prevent, correct, and alleviate movement dysfunction.Naturopathy: A drugless system of therapy, making use of physical forces such as air, light, water, heat, massage. Treatments are often diet- and nutrition-oriented with attention given to the patient's personal history and lifestyle. (From Cassileth, Alternative Medicine Handbook, 1998, p329)American Medical Association: Professional society representing the field of medicine.Earache: Pain in the ear.Hospital Shared Services: Cooperation among hospitals for the purpose of sharing various departmental services, e.g., pharmacy, laundry, data processing, etc.Manipulation, Spinal: Adjustment and manipulation of the vertebral column.Vitamin A: Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Vitamin D: A vitamin that includes both CHOLECALCIFEROLS and ERGOCALCIFEROLS, which have the common effect of preventing or curing RICKETS in animals. It can also be viewed as a hormone since it can be formed in SKIN by action of ULTRAVIOLET RAYS upon the precursors, 7-dehydrocholesterol and ERGOSTEROL, and acts on VITAMIN D RECEPTORS to regulate CALCIUM in opposition to PARATHYROID HORMONE.Plastics: Polymeric materials (usually organic) of large molecular weight which can be shaped by flow. Plastic usually refers to the final product with fillers, plasticizers, pigments, and stabilizers included (versus the resin, the homogeneous polymeric starting material). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Williams Syndrome: A disorder caused by hemizygous microdeletion of about 28 genes on chromosome 7q11.23, including the ELASTIN gene. Clinical manifestations include SUPRAVALVULAR AORTIC STENOSIS; MENTAL RETARDATION; elfin facies; impaired visuospatial constructive abilities; and transient HYPERCALCEMIA in infancy. The condition affects both sexes, with onset at birth or in early infancy.Equipment Reuse: Further or repeated use of equipment, instruments, devices, or materials. It includes additional use regardless of the original intent of the producer as to disposability or durability. It does not include the repeated use of fluids or solutions.Surgery, Plastic: The branch of surgery concerned with restoration, reconstruction, or improvement of defective, damaged, or missing structures.Specimen Handling: Procedures for collecting, preserving, and transporting of specimens sufficiently stable to provide accurate and precise results suitable for clinical interpretation.Blood Specimen Collection: The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.Disposable Equipment: Apparatus, devices, or supplies intended for one-time or temporary use.Roman World: A historical and cultural entity dispersed across a wide geographical area under the political domination and influence of ancient Rome, bringing to the conquered people the Roman civilization and culture from 753 B.C. to the beginning of the imperial rule under Augustus in 27 B.C. The early city built on seven hills grew to conquer Sicily, Sardinia, Carthage, Gaul, Spain, Britain, Greece, Asia Minor, etc., and extended ultimately from Mesopotamia to the Atlantic. Roman medicine was almost entirely in Greek hands, but Rome, with its superior water system, remains a model of sanitation and hygiene. (From A. Castiglioni, A History of Medicine, 2d ed pp196-99; from F. H. Garrison, An Introduction to the History of Medicine, 4th ed, pp107-120)Eucommiaceae: A plant family of the order Eucommiales, subclass Hamamelidae, class Magnoliopsida (some botanists have classified this in the order Hamamelidales or Urticales). Eucomia is an elmlike tree of central and eastern China. Leaves are alternate; deciduous flowers are solitary and unisexual and lack petals and sepals. The male flowers have 6 to 10 stamens and female flowers have one ovary of two carpels, one of which aborts during development so the fruit (a dry, winged structure) contains only one seed. The latex is a source of RUBBER. Tochu tea is an aqueous extract of Eucommia ulmoides leaves and a popular beverage in Japan. (Mutat Res 1997 Jan 15;388(1):7-20).Christianity: The religion stemming from the life, teachings, and death of Jesus Christ: the religion that believes in God as the Father Almighty who works redemptively through the Holy Spirit for men's salvation and that affirms Jesus Christ as Lord and Savior who proclaimed to man the gospel of salvation. (From Webster, 3d ed)Encephalitis, Japanese: A mosquito-borne encephalitis caused by the Japanese B encephalitis virus (ENCEPHALITIS VIRUS, JAPANESE) occurring throughout Eastern Asia and Australia. The majority of infections occur in children and are subclinical or have features limited to transient fever and gastrointestinal symptoms. Inflammation of the brain, spinal cord, and meninges may occur and lead to transient or permanent neurologic deficits (including a POLIOMYELITIS-like presentation); SEIZURES; COMA; and death. (From Adams et al., Principles of Neurology, 6th ed, p751; Lancet 1998 Apr 11;351(9109):1094-7)Literature, ModernMedicine in ArtEncephalitis Virus, Japanese: A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE), which is the etiological agent of Japanese encephalitis found in Asia, southeast Asia, and the Indian subcontinent.

Brusatol-mediated induction of leukemic cell differentiation and G(1) arrest is associated with down-regulation of c-myc. (1/11)

Employing the natural product quassinoid brusatol, we currently report cellular and molecular events leading to cell death or terminal differentiation in a panel of leukemic cells. Brusatol and bruceantin exerted significant cytotoxic effects with several leukemic cell lines, but not with K562 or normal lymphocytic cells. Cell lines that were less sensitive to the cytotoxic effects of brusatol responded primarily through induction of terminal differentiation. The differentiated phenotype in cell lines derived from acute or chronic myeloid leukemias (HL-60, K562, Kasumi-1, NB4, U937, BV173) was characterized for producing superoxide and non-specific esterase, and some with up-regulation of CD13 (cluster of differentiation) and down-regulation of CD15. Chronic myeloid leukemic cell lines, K562 and BV173, and acute lymphoblastic cell lines, SUPB13 and RS4;11, were induced to differentiate along the erythrocytic pathway. Withdrawal studies showed that brusatol treatment for 48 h was sufficient to induce commitment towards terminal differentiation in HL-60, K562 and SUPB13. Reh cells did not undergo maturation. Analysis of c-MYC protein expression revealed that brusatol or bruceantin down-regulated expression to undetectable levels in cell lines that were most sensitive, based on cell death or terminal differentiation. Generally, c-myc RNA was reduced, but to a lower extent than c-MYC protein levels, indicating c-myc expression was regulated by quassinoids at the post-transcriptional level. Thus, regulation of c-myc expression may represent a critical event that leads to terminal differentiation. Since these responses are facilitated at clinically achievable concentrations, quassinoids may be of value for the management of hematological malignancies.  (+info)

Formulation, preparation and evaluation of an intravenous emulsion containing Brucea javanica oil and Coix Seed oil for anti-tumor application. (2/11)

The purpose of this study was to prepare and evaluate the intravenous emulsion (BCOE) containing Brucea javanica oil (BJO) and Coix seed oil (CSO), which is used in anti-tumor treatment. The formulation and preparation of BCOE were systematically investigated. High-pressure homogenization, particle size distribution, zeta-potential and HPLC were carried out. The pharmacokinetics of the main component, oleic acid, and anti-tumor activity studies about the tumor growth inhibitory ratios (TGIR) and the mortality experiments were also employed to evaluate BCOE in vivo compared with BJO emulsion (BJOE) and CSO emulsion (CSOE) using S180 sarcoma-bearing mice. The final BCOE formulation was 10% (w/v) oils with BJO and CSO 3 : 1, 0.6% (w/v) Lipid E 80, 0.3% (w/v) Pluronic F-68 (F-68), 0.1% (w/v) sodium oleate and 2.5% (w/v) glycerin in water. The preparation conditions involved 70 degrees C for preparing the crude emulsion, 6 cycles for high-pressure homogenization at 500 bar, pH value was adjusted to 8.5 after high-pressure homogenization and 115 degrees C for 30 min in a rotating water bath for sterilization. The pharmacokinetics parameters showed the combination of BJO and CSO may not influence the elimination of BCOE and have no significant difference between BCOE and BJOE or CSOE. The data of TGIR and mortality indicated that BCOE could increase the anti-tumor activity of CSOE and reduced the toxicity of BJOE. The mortality study (BCOE 0, BJOE 63.3%, CSOE 13.3%) showed that BCOE greatly reduced the toxicity of BJOE and CSOE. Therefore, the development and application of BCOE will make an important contribution to anti-tumor therapy.  (+info)

Bioactivity-guided isolation of cytotoxic constituents of Brucea javanica collected in Vietnam. (3/11)

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Evaluation of efficacy of bruceine A, a natural quassinoid compound extracted from a medicinal plant, Brucea javanica, for canine babesiosis. (4/11)

Bruceine A, a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.) Merr., was evaluated for its antibabesial activity in vitro and in vivo. Bruceine A inhibited the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration compared with the standard antibabesial drug diminazene aceturate and killed the parasites within 24 hr at a concentration of 25 nM. Oral administration of bruceine A at a dosage of 6.4 mg/kg/day for 5 days resulted in no clinical findings in a dog with normal ranges of hematological and biochemical values in the blood. Three dogs were infected with B. gibsoni and two of them were treated with bruceine A at a dosage of 6.4 mg/kg/day for 6 days from day 5 post-infection. An untreated dog developed typical acute babesiosis symptoms including severe anemia, high fever, and complete loss of appetite and movement. However, the two bruceine A-treated dogs maintained their healthy conditions throughout the experimental period of 4 weeks although complete elimination of parasites from the peripheral blood was not achieved and decreases in the packed cell volume and the erythrocyte and platelet counts were observed. Since natural quassinoid compounds have been used as traditional medicines for the treatment of various ailments including cancer and malaria, the present results suggest that bruceine A or other related compounds are potential candidates for the treatment of canine babesiosis.  (+info)

Isolation of antibabesial compounds from Brucea javanica, Curcuma xanthorrhiza, and Excoecaria cochinchinensis. (5/11)

One new curcuminoid, 3'-demethoxycyclocurcumin (1), was isolated from Curcuma xanthorrhiza as an antibabesial compound, together with p-hydroxybenzaldehyde (2) and cleomiscosin A (3) from Brucea javanica and (+)-epiloliolide (4) from Excoecaria cochinchinensis. The antibabesial activities were examined in vitro, and compounds 1-4, and diminazene aceturate were studied with IC(50) values of 16.6, 7.6, 15.6, 10.0, and 0.6 microg/ml, respectively.  (+info)

Preparation, safety, pharmacokinetics, and pharmacodynamics of liposomes containing Brucea javanica oil. (6/11)

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NF-kappaB inhibitors from Brucea javanica exhibiting intracellular effects on reactive oxygen species. (7/11)

AIM: Brucea javanica was studied to identify nuclear factor kappaB (NF-kappaB) inhibitors exhibiting reactive oxygen species (ROS) intracellular amplification. MATERIAL AND METHODS: Eight compounds were evaluated for selective cytotoxicity using HT-29, HeLa, and HL-60 cells, and in a NF-kappaB assay. Active compounds were then tested using ROS and mitochondria transmembrane potential (MTP) assays. NF-kappaB and nuclear factor activated T-cell (NFAT) translocation were also assessed using their respective whole cell assays. RESULTS: Bruceajavanone B, bruceantin, bruceine A, (-)-hydnocarpin, and chrysoeriol exhibited cytotoxic potential and NF-kappaB p65 inhibition. Chrysoeriol exhibited selective cytotoxicity against leukemia cells with greater potency and also showed an ability to up-regulate NFAT transcriptional pathways through the amplification of intracellular ROS, in the presence of H2O2, to a greater degree than bruceantin and bruceine. CONCLUSION: Chrysoeriol selectively kills leukemic cells and potentiates the amplification of ROS levels. Therefore, chrysoeriol could serve as a potential chemotherapeutic modifier for leukemia chemotherapy since leukemia cells have a higher susceptibility to elevated ROS levels.  (+info)

Chemical components, pharmacological properties, and nanoparticulate delivery systems of Brucea javanica. (8/11)

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Background: The use of neo-adjuvant chemotherapy in treating osteosarcoma has improved patients average 5 year survival rate from 20% to 70% in the past 30 years. However, for patients who progress after chemotherapy, its effectiveness diminishes due to the emergence of multi-drug resistance (MDR) after prolonged therapy. Methodology/Principal Findings: In order to overcome both the dose-limiting side effects of conventional chemotherapeutic agents and the therapeutic failure resulting from MDR, we designed and evaluated a novel drug delivery system for MDR1 siRNA delivery. Novel biocompatible, lipid-modified dextran-based polymeric nanoparticles were used as the platform for MDR1 siRNA delivery; and the efficacy of combination therapy with this system was evaluated. In this study, multi-drug resistant osteosarcoma cell lines (KHOSR2 and U-2OSR2) were treated with the MDR1 siRNA nanocarriers and MDR1 protein (P-gp) expression, drug retention, and immunofluoresence were analyzed. Combination therapy of
We evaluated the safety and efficacy of induction chemotherapy with bevacizumab followed by maintenance chemotherapy with bevacizumab for advanced non-small cell lung cancer (NSCLC) in this multicenter phase II study. Chemotherapy-naïve patient with stage IIIB-IV or recurrent nonsquamous NSCLC were eligible. We planned approximately four cycles of induction cisplatin (75 mg/m2), pemetrexed (500 mg/m2), and bevacizumab (15 mg/kg) followed by maintenance with pemetrexed (500 mg/m2) and bevacizumab (15 mg/kg) until disease progression. Progression-free survival (PFS) was the primary endpoint. Forty patients received a median of four induction chemotherapy cycles. Of them, 35 (87.5%) patients received a median of nine maintenance chemotherapy cycles. The objective response was 70.6%, and the disease control rate was 97.1%. The median PFS was 10.8 (95% CI, 9.0-12.6), and overall survival was 48.0 (95% CI, 32.9-63.1) months. Median PFS of 23 patients with epidermal growth factor receptor (EGFR) mutations and
Image: preventdisease.com. Beyond limited empirical observations, not all medicinal plants have established scientific studies to support their effectiveness. However, in the case of Brucea javanica, it is one of those plants in which scientific investigations have provided enough evidence to prove that it has an impressive efficacy for the treatment of cervical, bladder and pancreatic cancers. Its selective toxicity has also been found to kill 70% of breast cancer cells.. Oncologists are still at a loss to find methods of selectively killing cancer cells through the standard protocols of treatment in chemotherapy and radiation. While damaging healthy cells is an inevitable process through most cytotoxic drugs, chemotherapy also triggers them to secrete a protein that sustains tumour growth and resistance to further treatment.. The Rest Of The Story… ...
Dear Histonetters, I am looking for stains that will identify the basic contents of cultured, mammary alveoli (mammospheres) of Kangaroo. Broad lipid ( ANY FAT STAIN THAT CAN BE DONE ON PARAFFIN EMBEDDED TISSUE???POSSIBLE??), carbohydrate (PAS?? ANY OTHER SUGGESTIONS) and protein stains (???) are required to determine what - IF any, different hormone combinations have/ effect on milk production. Any suggestions would be wonderful......our Histologist has made several good suggestions for me to try & we are both interested to see WHAT POSSIBILITIES/suggestions the scientific minds in Histo-land come up with. Thankyou in advance & Cheers, Sonia -- BRUCE ABALOZ PH:61383446282 HISTOLOGIST FAX:61383447909 DEPT.of ZOOLOGY EMAIL: [email protected] THE UNIVERSITY Of MELBOURNE. VICTORIA. AUSTRALIA 3010 Nobody Can Make You Feel Inferior Without YOUR Permission - Eleanor Roosevelt DANCE LIKE NO-ONES WATCHING Q: Whats a specimen? A: An Italian astronaut. ...
NanoBio Corporation, a Michigan based biotech, just announced that they have received a $1.5 million grant (1) from the National Institute of Allergy and Infectious Diseases (NIAID) to run Phase II studies on its vaccine candidate for prevention (2) of herpes simplex virus-2 (HSV-2) infection (3). The company developed a nanoemulsion oil-in-water (NE) technology (4)- a mixture of very small beads of oil and water-to help deliver vaccines both intranasally and intramuscularly.. During pre-clinical studies, which were conducted by researchers at the Cincinnati Childrens Hospital Medical Center, a nasallly administered version of NanoBios NE vaccine has been studied in guinea pigs-a model that is known to be predictive of efficacy in humans. The results were impressive.. Dr. David I. Bernstein, Professor of Pediatrics the Medical Center said, "NanoBios intranasal vaccine is one of the only vaccine candidates weve studied that has shown efficacy in both the prophylactic and the therapeutic ...
Auxilium Pharmaceuticals recently dosed its first patient for the phase II study on Xiaflex for the treatment of frozen shoulder syndrome (adhesive capsulitis).
PhyCox HA Soft Chews is a hypoallergenic joint support formula with a combination of natural compounds and synergistic ingredients to reduce inflammation and provide a joint support matrix for healthy synovial maintenance as well as bone & muscle support.
... is a special blend of Amino Acids, herbs and synergistic ingredients designed to support mental alertness, focus and memory. Stimulant free this powerful FOCUS formula can be used before any activity which requires increased focus, drive and determination. The amino acids that have been used in this formula have shown in studies to reduce environmental stress, and to increase the availability of neurotransmitters to the brain. The adaptogenic herbs are used traditionally to help reduce the physical and mental effects of stress on the body.. The support from nitrates rounds the formula off nicely providing an effective clinical dose that stimulates blood flow and increases oxygen delivery. The absence of stimulants means FOCUS formula can assist with preventing burnout and fatigue-based conditions, most often caused by the overuse of stimulant based pre-workout supplement regimes. Gram for gram FOCUS formula is one of the strongest and most comprehensive formulas of its kind.. ...
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Intravenous lipid constituents have different effects on various biological processes. Some of these effects are protective, while others are potentially adverse. Phytosterols, in particular, seem to
LAssociazione ha lo scopo di promuovere il progresso oncologico nel campo clinico, sperimentale e socio-assistenziale, la prevenzione primaria e secondaria, la qualità delle cure oncologiche, la continuità terapeutica del paziente oncologico, Home - AIOM - Associazione Italiana di Oncologia Medica
As the cost of drug development is always many times more than that of drug discovery, predictive methods aiding in the screening of bioavailable drug candidates are of profound significance. In this paper, a novel method for screening bioactive compounds from traditional Chinese medicines (TCMs) was developed by using living cell extract and gas chromatography (GC)-mass spectrometer (MS). The method was validated by using elemene emulsion injection (EEI), a typical TCM with known active compound, to interact with murine ascites hepatocarcinoma cell strain with high metastatic potential (HCa-F). Finally, the method was applied to screen the bioactive compounds from multi-component zedoary turmeric oil and glucose injection (ZTOGI). After HCa-F cells was incubated in ZTOGI, ethyl acetate (EtOAc) was used to extract the compounds in the cells for GC-MS analysis. Fourteen compounds were detected in the desorption eluate of HCa-F cell extract of ZTOGI, and further identified by MS. Curzerene and ...
Dear Histonetters, Am wondering whether any of you, know of/recommend a good staining technique for the detection of lipopolysaccharide (LPS). Silver staining is often done to detect H. pylori in situ, I think because it does stain LPS, but I am wondering whether I could use it to visualize an enriched flagella prep (the flagella are about 1-2 um long). Appreciate any response, Cheers - Bruce in OZ -- BRUCE ABALOZ PH:61383446282 HISTOLOGIST FAX:61383447909 DEPT.of ZOOLOGY EMAIL: [email protected] THE UNIVERSITY Of MELBOURNE. VICTORIA.AUSTRALIA 3010 http://www.zoology.unimelb.edu.au/ Nobody can make you feel inferior without your permission. - Eleanor Roosevelt DANCE LIKE NO-ONES WATCHING ******************************************************************************** This email and any attachments may contain personal information or information that is otherwise privileged, confidential or otherwise protected from disclosure/subject of copyright. Any use, disclosure or copying of any part ...
A suitable management of the pharmaceutical property is needed and helpful to design a desired nanoparticulate delivery system, which includes the carrier nature, particle size and size distribution, morphology, surfactant stabiliser according to the technique applied, drug-loading ratio and encapsulation efficiency, surface property, etc. All will influence the in vitro release, in vivo behaviour and tissue distribution of administered particulate drug loaded nanoparticles. The main purpose of the present work was to determine the effect of drug loading ratio when employing TPGS as surfactant stabiliser and/or matrix material to improve the nanoparticulate formulation. The model drug employed was paclitaxel ...
ESMO is a Swiss-registered not-for-profit organisation. All funding for this site is provided directly by ESMO or via grants from the sponsors and supporters.. Via L. Taddei 4, 6962 Viganello - Lugano - CH © Copyright 2017 European Society for Medical Oncology All rights reserved worldwide.. ...
NO CRASH THERMOGENIC. A science-backed, cutting-edge formula that contains patented ingredients for rapid and sustained release thermogenesis, RESULTS SCULPTIFY™ begins working immediately, increasing thermogenesis, lipolysis (fat burning) and overall mental focus and clarity. Unlike traditional fat burners that can spike energy and crash energy quickly, leaving you with little else, RESULTS SCULPTIFY™ is formulated with specific ingredients that will deliver rapid and sustained energy levels. A primary stimulant in the RESULTS SCULPTIFY™ formula was clinically proven to last 6 times longer than traditional caffeine alone! Each serving also contains the patented Advantra Z®, which is structurally similar to ephedrine but works by activating different beta receptors to trigger fat release and metabolism. This thermogenic compound promotes fat oxidation, without the jittery effects associated with ephedrine. RESULTS SCULPTIFY™ delivers a blend of synergistic ingredients that stimulate ...
Experiments on the orientation of Meloidogyne javanica larvae relative to roots are described which support the root-attraction hypothesis in contrast to the random-movement hypothesis. Further experiments on the nature of this attraction to roots suggest that it is probably due to several stimuli which may vary in importance.
Primalan Finest Almond Oil Emulsion can be used best in conjunction with Dolerma. Recommended use is to apply Dolerma first and follow up with Primalan. Primala
B. javanica seeds exhibit intermediate storage behaviour characterized as being tolerant to desiccation but sensitive to freezing temperatures. Freshly mature seeds survive when they are desiccated to 5.3-12.5% MCs. Viability of seeds with 3.7-12.5% MCs drop significantly at -20oC after 24 months of hermetic storage. The optimum seed moisture contents of B. javanica are 8, 5-13, and 5-8% for -20, 4, and 15oC storage, respectively. Longevity of seeds stored at 4oC is better than those at -20 and 15oC (Yang-JengChuann et al., 2006 ...
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ST-Phile was a media science fiction fanzine devoted to Star Trek published by Juanita Coulson, and edited by Juanita Coulson and Kay Anderson. ST-Phile was published in Indiana, U.S.A., and was first released in January 1968, during the broadcast of the original Star Trek television series. It was a mimeographed publication of 29 pages, and was entirely non-fiction, featuring articles, essays, verse and art work. Art work for the first issue was by John D. Berry (Egoboo), Juanita Coulson, Margaret Dominick, Devra Langsam (Spockanalia), Charles Rein, and Bjo Trimble (Melange, Shangri LAffaires), with a front cover by Doug Lovenstein. Contributors of writing included articles by Kay Anderson, Ruth Berman (Despatch, Inside Star Trek, T-Negative), Juanita Coulson, S.M. Hereford, Shirley Meech (Plak-Tow), Gene Roddenberry, Bjo Trimble, John Trimble (Pas-Tell, Melange, Shangri LAffaires), and Bob Vardeman (Sandworm). The second issue was released in November 1968, and is 44 pages. The art work for ...
1BJO: Crystal structure of phosphoserine aminotransferase from Escherichia coli at 2.3 A resolution: comparison of the unligated enzyme and a complex with alpha-methyl-l-glutamate.
In the present study, we demonstrated PCV and EGFR mutation status as independent prognostic factors in untreated advanced lung adenocarcinoma patients. We also showed that PCV , 2.2 ng/ml was a predictor of a favorable outcome in both advanced lung adenocarcinoma patients with wild-type and mutant EGFR.. Serum CYFRA 21-1 has been reported as a prognostic factor in patients with a variety of cancer types, including resectable NSCLC [39, 40], biliary tract cancer [41], urothelial cancer [42], head and neck cancer [43], esophageal cancer [44], and cervical cancer [45].. A meta-analysis of CYFRA 21-1 as a prognostic indicator in advanced NSCLC patients showed that the PCV may be a reliable prognostic factor [29], however, since non-adenocarcinoma accounted for 65% of the cases and squamous cell carcinoma for 50%, the role of serum CYFRA 21-1 as a prognostic indicator in the lung adenocarcinoma population remained unclear. Moreover, in a study of PCV as a prognostic indicator in advanced NSCLC ...
RESULTS AND DISCUSSION. All of the treatments had significantly lower aboveground weights compared to the control treatment without fungus and nematode. It was found that the weight of aboveground parts of to mato plants cultivated in pots without nematodes was lower than those infested with M. javanica (Table 1). The application of fungal isolates Pc-3, Pc-10, and Pc-28 of P. chlamydosporia var. chlam-ydosporia to the soil, individually or combined did not reduce the number of galls of M. javanica when compared to the nematode alone treatment (Table 1). There was a significant difference in the number of M. javanica eggs per root when the fungal isolate Pc-10 was incorporated individual ly into the soil compared to the nematode alone (307.7 and 597.2 eggs per root, respectively).. Previous experiments (Lopes et al., 2007; Dallemole-Giaretta et al., 2012) with the same fungal isolates used in this experiment demonstrated that they are able to control the root-knot nematode. However, the results ...
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The first generation EGFR TKIs gefitinib and erlotinib provide significant clinical benefit in patients with advanced lung adenocarcinoma harbouring activating EGFR mutants (EGFRm+), but patients will ultimately develop disease progression due to acquired resistance. Acquisition of the EGFR T790M mutation is the most common mechanism of drug resistance, detected in more than 50% of gefitinib/erlotinib resistant patients. Current therapeutic strategies are limited for advanced lung adenocarcinoma patients with EGFR T790M (EGFRm+/T790M), so this remains a key area of unmet need. AZD9291 (structure to be disclosed at meeting) is an oral, irreversible, third generation, selective inhibitor of both EGFR activating (EGFRm+) and resistance (EGFRm+/T790M) mutations. The mechanistic and functional activity of AZD9291 was characterised in vitro and in vivo across a number of cell lines harbouring various EGFR-mutations or wild type EGFR. Presented data shows AZD9291 potently inhibits EGFR phosphorylation ...
In situ effective separation of oil pollutants including oil spills and oil emulsions from water is an emerging technology yet remains challenging. Hydrophobic micro- or nano-materials with ferromagnetism have been explored for oil removal, yet the separation efficiency of an oil emulsion was compromised due to the
This made me to think about invasive cover crops like - Pueraria Javanica (Tropical Kudzu) and Mucuna Bracteta. Mucuna was seen in rubber plantations in Kerala and they keep a ground cover green even during peak summer. I searched to check if anyone is using in orchards and found two farmers in Kerala. One was a farmer from Kannur, Kerala named Francis and he used Mucuna as cover crop in his pepper crop - www.nif.org.in/upload/pdf_file/francis_pa.pdf. Talked to him and he was recommending Mucuna and even though it is invasive, it can be easily controlled. Another farmer was Jayadevan, Alanellur, Kerala and he was not completely for it, since it just takes over and spreads to different places and it can not be used as fodder. He had used it in one area of coconut farm and that area didnt require any watering, he was planning to replace it. Since there were plenty of red ants, there was no threat of snakes. I talked to Kailashamurthy of Mysore and he suggested to use Pueraria. Pueraria also is ...
Varieties javanica: with the name O. sativa var. javanica are broad-grained and thrives under tropical conditions, was identified based on morphology and initially called javanica, but is now known as tropical japonica with the name O. sativa var. tropical japonica. Examples of these varieties include the medium grain Tinawon and Unoy cultivars, which are grown in the high-elevation rice terraces of the ...
Meskipun cuma satu foto tapi ini satu bukti yang harus tetap dipertahankan. Jenis ini ternyata jenis endemik Jawa. Capung dengan ukuran besar ini menarik sekali untuk diabadikan. Hari ini (26/04/13) bersama sesepuh Indonesia Dragonfly Society capung besar ini terlihat sedang berjemur dekat rumpun bambu yang tidak jauh dari sumber air, Sungai. Memang beda kalau kalau…
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An objective postprocessing technique for detecting SLS in radiographic images of BSCC heart valves has been developed. The results of this study indicate that two of the quantitative variables developed for detecting SLS (namely, DIPI ratio and gap half-width) are diagnostic and that the accuracy in detection of SLS with either of these two variables was equal to that of the expert subjective reviewers. Although offset appears to be a strong visual cue for the expert reviewers, the confounding factor of image magnification in this study made it difficult to adequately assess its utility as a discriminating variable. However, on the basis of the results before magnification, maximum offset deviation may also be significant in discriminating SLS legs. Due to the small sample size before magnification, it was not possible to develop a classification model based on both offset and gap measures. Yet this type of model could be the most accurate predictor of SLS and surpass the predictive ...
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Discussion In general, the onset of responses governing pest resistance in plants depends on the genotype/species, magnitude and rapidity in which the genes are expressed during the infection. Recently modulated transcript abundance was demonstrated in resistant and susceptible soybean roots during SCN interactions (Mazarei et al., 2011) and also during susceptible soybean-RKN interaction (Ibrahim et al., 2011). The goal of this work was to describe transcriptional changes in PI 595099 resistant soybean line roots during the early stages (6, 12, 24, 48, 96, 144 and 192 h) of infection with M. javanica. The in silico functional characterization of the transcribed reads from both libraries revealed a number of genes related either to biotic or abiotic stresses. Here, among the defense responses of PI 595099 towards M. javanica are included up-regulated genes encoding for zinc finger, AN1-type; A20-type; Nuclear transport factor 2 (NTF-2); Auxin-repressed protein; SLAH4 (SLAC1 Homologue 4); SLAH1 ...
LifeSource Vitamins Candida Cleanse is a combination of herbal ingredients (Pau DArco, Black Walnut, and Oregano Oil), Biotin (a B-complex vitamin) and Caprylic Acid (a naturally occurring fatty acid derived from plant oils). These synergistic ingredients help to support a healthy balance of intestinal bacteria.
Save 39% Solaray - Calcium Citrate Supreme 180 Capsules Calcium Citrate Supreme™ Advanced Bone Building Supplement The mineral citrates in this product are bonded with natural citric acid and are specially formulated for people with insufficient stomach acid. Important synergistic ingredients have been added to provide superior utilization of calcium for healthy bones.
Teng and coworkers (in an earlier issue of BJO) suggested that a tight neck tie might increase intraocular pressure. Theelen and coworkers challenge this point of view. In a study of 23 right eyes of 23 healthy subjects, both male and female, intraocular pressure was measured by applanation tonometry with a TonoPen in four different conditions: (1) open collar upright; (2) head in the headrest of a slit lamp, (3) tight neck tie upright, (4) in a slit lamp position. In this study tight neck ties did not significantly affect intraocular pressure measurements in healthy subjects. However, retroflexion of the neck significantly increased intraocular pressure measurements and the authors suggest that the slit lamp position may not be the ideal position to measure intraocular pressure accurately. See p 1510. ...
Sprawdź ile zapłacisz za lek mineral oil emulsion w aptece, znajdź tańsze zamienniki leku. Określ swoje uprawnienia i sprawdź jakie zniżki Ci przysługują.
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The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details ...
See, this could have developed into the cloud we see here, after being initially released. Its hard to say without any firm idea of the chemical components of the fog itself. Incidentally, I fail to see how it is that no one has discovered what those chemical components are yet. There must be trace evidence all over the bloody place, given the size of that cloud ...
Animals grow by ingesting a variety of nutrients, including carbohydrates, lipids, sugars, fats and proteins, then digesting them into their chemical components. These components are distributed...
THE EFFECT OF CURCUMA XANTHORRHIZA ETHANOL EXTRACT ON THE VIABILITY OF STREPTOCOCCUS MUTANS AND AGGREGATIBACTER ACTINOMYCETEMCOMITANS (DENTAL BIOFILM RESEARCH: IN VITRO STUDY)
Saputri, F. C., Astari, C., Janatry, D. A., ., A., & Kusmana, D. (2018). HEPATOPROTECTIVE EFFECT OF BELLAMYA JAVANICA: ASPARTATE TRANSAMINASE, ALANINE AMINOTRANSFERASE, AND ALKALINE PHOSPHATASE ACTIVITY, AND LIVER HISTOPATHOLOGY IN MICE INDUCED WITH CARBON TETRACHLORIDE. International Journal of Applied Pharmaceutics, 10(1), 203-207. https://doi.org/10.22159/ijap.2018. ...
CALGARY - The Alberta Energy Regulator says a pipeline owned by Calgary-based Mount Bastion Oil & Gas Corp. has leaked about 560 barrels of an oil and water mixture at a northern Alberta wellsite.. AER spokesman Jordan Fitzgerald says the regulator has staff supervising cleanup by the company at the site about 65 kilometres northwest of Red Earth Creek, which is about 420 kilometres north of Edmonton.. He says the company reports the oil emulsion spill affected about 5,000 square metres of swampy muskeg, adding there have been no reports of injury to wildlife or damage to nearby creeks.. Data on the AER website indicates the spill is the largest of three pipeline leaks the company has reported in the past 16 months.. In July 2016, it reported a pipeline leaked about 315 barrels of oil and 125 barrels of produced saltwater at a site 75 kilometres northwest of Red Earth Creek, and in December 2016 it reported a leak of three barrels of oil and 120 barrels of saltwater at a site 30 kilometres ...
English F.P., McDermott N.D. and Siu S.K. (1973) Cilia graft. British Journal of Ophthalmology, 57 10: 763-765. doi:10.1136/bjo.57.10.763 ...
Page contains details about nanoparticulate tantalum oxide with positively charged trioxysilane ligand . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
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Chemicals and biomolecules are common in every lab as many techniques rely on reagents such as buffers (biochemical reagents) and enzymes (biomolecules). Such research also requires the use of chemical components like acids, bases, salts and solvents.
Two (2) capsules supply: Proprietary Blend. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 950 mgDill (Anethum graveolens) (seed), Stemona sessilifolia (powder and extract), Artemisia absinthium (extract) (shoots, leaves), Brucea javanica (powder and extract), Pulsatilla chinensis (powder and extract) (rhizome), Picrasma excelsa (extract) (bark), Acacia catechu (extract) (stem), Hedyotis diffusa (powder and extract), Yarrow (Achillea millefolium) (extract) (leaf, flower). RECOMMENDATION: Two (2) capsules taken two (2) times each day as a dietary supplement or as otherwise directed by a healthcare professional. Contains: 120 Capsules Dysbiocide - supplies a proprietary blend of herbs and herbal extracts to support normal gut health.Caution: Not recommended for pregnant or lactating women.
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Result of KLT and LCMS (Liquid Chromatography Mass Spectroscopy) showed that the water extract and ethanol extract of the parasite from species D. pentandra that grow on various host have the same major compounds suspected is a compound flavonol glycosides quersitrin which is a marker taxonomy from the family Loranthaceae. Quersitrin also been isolated from parasite duku (M. cochinchinensis) (Jamilah, 2003). Test results with cancer cells (in vitro), 3 new extract showed excellent activity in cancer cells, one of them is a parasite carambola leaf extract water (YI) (M. cochinchinensis). Test results of in vitro anticancer (Artanti et al., 2003), showed that the water extract of the parasite starfruit (YI) (M. cochinchinensis) have IC50 = 0,63 ppm against breast cancer cells MCF7; In vitro anticancer trials have also been conducted on cancer cells L1210 (IC50 = 41,0 ppm), HCT116 (IC50 , 20 ppm), and A431 (IC50 , 20 ppm). Cancer cell B16 viability assay results that this extract at a concentration ...
Canine babesiosis is a life threatening condition for dogs and experts are warning dog owners about the deadly tick borne disease which has entered the UK…
Learn more about Canine Babesiosis, symptoms range from mild to severe and include lethargy, fever, anaemia, an enlarged abdomen, weight loss and jaundice.
Definition: one of three metabolic pathways for carbon fixation in photosynthesis, along with C4 and CAM. This process converts carbon dioxide and ribulose bisphosphate (RuBP, a 5-carbon sugar) into 3-phosphoglycerate through the following reaction: CO2 + H2O + RuBP → (2) 3-phosphoglycerate This reaction occurs in all plants as the first step of the Calvin-Benson cycle ...
The pathophysiology of non-arteritic ischaemic optic neuropathy (NAION) is only incompletely understood. Abu-Amero and Bosley investigated 19 patients with NAION and, compared to a control group of 32, they found increased relative mitochondria DNA content in leucocytes in patients with NAION. They suggest that this may possibly be a response to oxidative stress. A relative increase in mitochondrial DNA content in leucocytes may be a relative risk factor in the development of NAION. See p 823. ...
Detail záznamu - The Production of Nanoparticulate Ceria Using Reverse Micelle Sol-Gel Techniques - Detail záznamu - Knihovna Akademie věd České republiky
The major chemical components of cells include the nucleic acids RNA and DNA, polysaccharides (carbohydrates), fatty materials (lipids), and many thousands of different proteins. Proteins catalyze most of the metabolism, the network of chemical reactions by which cells construct their […]
A large team of scientists used a combination of complex, cutting-edge-science testing methods to expand the understanding of the chemical components present in weathered oil.
Abaxially anthocyanic leaves of deeply-shaded understorey plants play important ecological significance for the environmental adaption. In contrast to the transient pigmentation in other plants, anthocyanins are permanently presented in these abaxially red leaves, however, the mechanism for the pigment maintenance remains unclear. In the present study, we investigated phenolic metabolites that may affect pigment stability and degradation in Excoecaria cochinchinensis (a bush of permanently abaxial-red leaves), via a comparison with Osmanthus fragrans (a bush of transiently red leaves). High levels of galloylated anthocyanins were identified in the Excoecaria but not in the Osmanthus plants. The galloylated anthocyanin showed slightly higher stability than two non-galloylated anthocyanins, while all the 3 pigments were rapidly degraded by peroxidase (POD) in vitro. High levels of hydrolysable tannins [mainly galloylglucoses/ellagitannins (GGs/ETs)] were identified in Excoecaria but none in Osmanthus. GGs
The effect of grasses on the reaction of Desmodium ovalifolium (accession CIAT 350) to Meloidogyne javanica was measured. The nematode was less pathogenic to the legume in association with 22 of 49 grasses, including accessions of the promising pasture grasses Andropogon gayanus, Brachiaria humidicola, B. mutica, B. ruziziensis, Panicum maximum, and Hemarthria altissima. Roots of these grasses may produce substances that are toxic to M. javanica. ...
The present invention provides a composition comprising a cefditoren, or a salt, derivative, prodrug, or other form thereof, for example, cefditoren pivoxil, useful in the treatment and prevention of infections and related conditions. The invention provides a composition which comprises nanoparticulate particles comprising the cefditoren, or a salt, derivative, prodrug, or other form thereof and at least one surface stabilizer. The nanoparticulate particles have an effective average particle size of less than about 2000 nm. The invention provides also a composition that delivers a cefditoren, or a salt, derivative, prodrug, or other form thereof, or nanoparticles comprising the same, in a pulsatile or continuous manner.
A localized pleurodesis for lung devices created utilizing a combination of a mechanical component and a chemical component. The chemical component is utilized to create an acute adhesion between the
The T.A.P. proposal document is from 2001. It does not provide evidence that chemtrails are currently underway. What it does, however, is outline plans for the T.A.P. program that include activities very similar to those many of us are witnessing at the present time. The T.A.P. proposal clearly states there are health risks that exist, the extent of which (at least at the time) were unknown and needed to be researched further. Coincidentally, many citizens in the regions who report ongoing chemtrails in their skies have also been stricken with health problems since the alleged chemtrails began. Some of their symptoms coincide with exposure to certain chemical components of the proposed aerosols ...
Background Malignant pleural effusion (MPE) is associated with advanced stages of lung cancer and is mainly dependent on invasion of the pleura and expression of vascular endothelial growth factor (VEGF) by cancer cells. As MPE indicates an incurable disease with limited palliative treatment options and poor outcome, there is an urgent need for new and efficient treatment options. Methods In this study, we used subcutaneously generated PC14PE6 lung adenocarcinoma xenografts in athymic mice that developed subcutaneous malignant effusions (ME) which mimic pleural effusions of the orthotopic model. Using this approach monitoring of therapeutic intervention was facilitated by direct observation of subcutaneous ME formation without the need of sacrificing mice or special imaging equipment as in case of MPE. Further, we tested oncolytic virotherapy using Vaccinia virus as a novel treatment modality against ME in this subcutaneous PC14PE6 xenograft model of advanced lung adenocarcinoma. Results We ...
Veternarians expressed grave concern when the regulations governing the import of dogs into the UK were relaxed in 2005 in compliance with EU regulations concerning the free movement of animals. Sadly it appears that their predictions have come true and this relaxation has led to the import of a tick borne disease new to the UK, along with the dogs. Coupled to this the recent mild, wet winters in Britain have led to an increase in tick populations. Vets who initially treated the infected dogs have pointed out that the thousands of eggs laid by an infected female tick will all carry the parasite so canine babesiosis could rapidly spread to other areas of the UK.. At the risk of "shutting the stable door after the horse has bolted" perhaps it is time to rethink the relaxation of regulations regarding the free movement of dogs between the UK and mainland Europe.. ...
Passiflora cochinchinensis - Species Dictionary - Global : iSpot Nature - Your place to share nature. iSpot is a website aimed at helping anyone identify anything in nature. Once youve registered, you can add an observation to the website and suggest an identification yourself or see if anyone else can identify it for you.
A.H.M. Shafiqul Islam, A.H.M. Shafiqul Islam (2009) Demonstration of antigenic and specific outer membrane protein(s) of acinetobacter baumann II[R5-130.5]. Masters thesis, Universiti Sains Malaysia.. Ab Halim, Mohd Rohaimi (2014) Validation Of GC-MS Method For Standardization Of Curcuma Xanthorrhiza Extracts Using Biochemical Markers, AR-Curcumene And Xanthorrhizol. Masters thesis, Universiti Sains Malaysia.. Ab. Latip, Laili Suriani (2002) Predictors of important CT findings and neurosurgical intervention in minor head injury. Masters thesis, Universiti Sains Malaysia.. Ab. Rahman, Rahiza (2002) A study of knowledge, attitude and practice towards contraception among nursing staff in district Kota Bharu. Masters thesis, Universiti Sains Malaysia.. Abbood Al-Dulaimi, Saif Hasan (2013) Classroom acoustic measurements and audiological screening of year 1 school children. Masters thesis, Universiti Sains Malaysia.. Abd Rahman, Ariza (2001) A study of neurobehavioural effects of long-term exposure ...
Through IFTs focus on food chemistry, youll keep abreast of the study and analysis of food chemical components and their chemical reactions and interactions, individually or in food systems. Well examine reactions and interactions as chemical components undergo processing, packaging, storage, and digestion; explore new analytical techniques; and understand advances in bioactive research.
Carbon soccer balls can form into gels all by themselves, say chemists, overturning the long-held belief that gels must consist of at least two chemical components.
Two root-knot nematode species, Me/oidogyne incognita and M.javanica, were studied with regard to their seasonal population fluctuations on grapevines growing in two vastly different climatic areas. Regular observations on reproduction and numbers of larvae in the soil were compared with patterns of root growth, soil temperature and moisture. Population fluctuations of the two species showed similar trends in spite of the climatic differences in the two areas, but M. incognita in the northern Cape reached higher populations. Larvae populations in the soil declined in summer in both areas and increased during autumn to reach peaks in winter. With the onset of root growth in spring, larvae numbers decreased in the soil, as a result of large scale root penetration.. ...
TY - JOUR. T1 - Late-onset proptosis with Baerveldt glaucoma implants. AU - Patterson, E.. AU - Ng, J.. AU - Jamil, A.. AU - Cioffi, G. A.. AU - Mansberger, S. L.. PY - 2008/4/1. Y1 - 2008/4/1. UR - http://www.scopus.com/inward/record.url?scp=41849125999&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=41849125999&partnerID=8YFLogxK. U2 - 10.1136/bjo.2007.121194. DO - 10.1136/bjo.2007.121194. M3 - Letter. C2 - 18055571. AN - SCOPUS:41849125999. VL - 92. SP - 580. EP - 582. JO - British Journal of Ophthalmology. JF - British Journal of Ophthalmology. SN - 0007-1161. IS - 4. ER - ...
The present invention is directed to nanoparticulate compositions comprising a poorly soluble drug and at least one copolymer of vinyl pyrrolidone and vinyl acetate as a surface stabilizer adsorbed to the surface of the drug. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate composition of the invention, methods of making and using such nanoparticulate and pharmaceutical compositions.
Systems and methods for providing in situ, controllably variable concentrations of one, two or more chemical components on a substrate to produce an integrated materials chip. The component concentrations can vary linearly, quadratically or according to any other reasonable power law with one or two location coordinates. In one embodiment, a source and a mask with fixed or varying aperture widths and fixed or varying aperture spacings are used to produce the desired concentration envelope. In another embodiment, a mask with one or more movable apertures or openings provides a chemical component flux that varies with location on the substrate, in one or two dimensions. In another embodiment, flow of the chemical components through nuzzle slits provides the desired concentrations. An ion beam source, a sputtering source, a laser ablation source, a molecular beam source, a chemical vapor deposition source and/or an evaporative source can provide the chemical component(s) to be deposited on the substrate.
Volunteers in the Phase I study, patients with advanced lung cancer that had failed to respond to all conventional therapies, took several Celebrex pills and one Tarceva pill each day. After eight weeks, researchers looked at response rates. Patients were able to stay on the study as long as they didnt experience tumor growth. The longest duration of response was 93 weeks, Reckamp said, about three to four times longer than the average duration of response for a patient with advanced lung cancer ...
Brouqui, P., Bacellar, F., Baranton, G., Birtles, R. J., Bjoërsdorff, A., Blanco, J. R., Caruso, G., Cinco, M., Fournier, P. E., Francavilla, E., Jensenius, M., Kazar, J., Laferl, H., Lakos, A., Lotric Furlan, S., Maurin, M., Oteo, J. A., Parola, P., Perez-Eid, C., Peter, O., Postic, D., Raoult, D., Tellez, A., Tselentis, Y. and Wilske, B. (2004), Guidelines for the diagnosis of tick-borne bacterial diseases in Europe. Clinical Microbiology and Infection, 10: 1108-1132. doi: 10.1111/j.1469-0691.2004.01019.x ...
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The present invention is directed to nanoparticulate compositions comprising statin such as lovastatin or simvastatin. The statin particles of the composition have an effective average particle size o
Lancerin, isolated from the root bark of Cudraniu cochinchinensis, possesses anti-lipid peroxidation. - Mechanism of Action & Protocol.
Home Use of Omegaven®:. In order for a subject to receive the Omegaven® at home through a home health care agency, subjects will first be required to be admitted to Texas Childrens Hospital for 72 hours in initiate the administration of the Omegaven®. This will allow time for observation of any unexpected side effects and for parents to be provided education on home TPN and Omegaven®.. If a subject has already received Omegaven® either at TCH or at another hospital, they will not be required to be admitted for the 72 hour inpatient admission prior to starting Omegaven® at home. Parent training will occur during the previous hospital admission and will continue through the TCH Pediatric Intestinal Rehabilitation Clinic.. Outpatient Monitoring:. After the initial evaluation by the TCH Pediatric Intestinal Rehabilitation Clinic physicians, subjects will return to the clinic for routine follow-up. Subjects will be asked to return to the clinic every 2 weeks for the first 2 months of ...
Entropy was a science fiction fanzine by Terry Carr. The first, and only issue of Entropy appeared in November 1964, published in Brooklyn, New York, U.S.A. It was an 8 1/2 by 11 inch fanzine of 26 pages. This issue was distributed with the November 1964 FAPA mailing, the December 1964 OMPA mailing, and the January 1965 SAPS mailing. Entropy was dedicated to reprinting work by fanzine writers that had appeared as contributions in older fanzines (not their own fanzines), and combining them with newer illustrations. Reprints included Mal Ashworth, from Brennschluss; Jack Darrow, from The Fourteen Leaflet; Dave English, from Fiendetta; Dean Grennell, from Contour; Walt Liebscher, from A Bas; Bob Tucker, from Oopsla!; and Sam Youd, from Fission. Art work was contributed by Mervyn Barrett, Lee Hoffman (Science Fiction Five Yearly), Steve Stiles, ATom (The ATom Anthology), and Bjo Trimble (Melange). At the same time as the fanzine, Terry Carr also released Entropy Booklets, which were comprised of ...
Egg / linseed oil emulsion Ground for canvas and panels I Egg Raw linseed oil Water Titanium white (or other) pigment Rabbit skin glue solution (1:30, glue to water) Sized panel (1:15 solution) or sized linen (1:30 solution) Break the egg into a glass jar and shake. Mark the level on the side of the jar and double the existing level with the oil. Again mark the level and double the quantity with water and shake to form an emulsion. This will store for 1 week in the fridge. Put some Titanium white pigment onto a glass slab and Read more. ...
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Sigma-Aldrich offers abstracts and full-text articles by [Hank Cheng, David A Davis, Sina Hasheminassab, Constantinos Sioutas, Todd E Morgan, Caleb E Finch].
Jaundice can cause both the skin and the whites of your eyes to turn yellow due to bilirubin -- a chemical component of hemoglobin. During the breakdown of...
ISBN 978-1-899468-67-6. "Daniel Bruce - A Squad". Scottish Football Association. Archived from the original on 16 June 2011. " ...
... s are quassinoids isolated from Brucea antidysenterica. Imamura, K; Fukamiya, N; Nakamura, M; Okano, M; Tagahara, K; ... Bruceanol-A and -B, two new antileukemic quassinoids from Brucea antidysenterica". Journal of Natural Products. 48 (6): 972-5. ... Lee, KH (1995). "Bruceanols G and H cytotoxic quassinoids from Brucea antidysenterica". Journal of Natural Products. 58 (12): ...
... brucea (wd , gwp gwe g , in it p) MeSH B06.388.100.898.333 --- eurycoma (wd , gwp gwe g , in it p) MeSH B06.388.100.898.555 ...
Brucea javanica oil, extracted from the seeds of the Brucea javanica. The oil has been shown to be effective in treating ... Zhang, Hong; Yang, Jing Yu; Zhou, Fan; Wang, Li Hui; Zhang, Wen; Sha, Sha; Wu, Chun Fu (2011). "Seed Oil of Brucea javanica ... Lou, Guo-Guang; Yao, Hang-Ping; Xie, Li-Ping (2010). "Brucea javanica Oil Induces Apoptosis in T24 Bladder Cancer Cells via ...
Brucea is the original name of Bruceomyces, published by Finnish mycologist Jouko Rikkinen in 2003. Rikkinen and colleagues ... renamed the genus in 2012 after it was discovered that Brucea was a junior homonym of a plant genus. The generic name honors ...
"Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruits, Simarouba amara stem, and a number of ...
Rekao je: "Batman je skrivena, demonska strana Brucea Waynea. Batman je u potpunosti iskreno biće koje se mora kontrolirati. On ... Glumačka postava je hvaljena zbog dojmljivih izvedbi, a Bale je pokupio najviše pohvala zbog svojeg portreta Brucea Waynea i ... željena uloga Brucea Waynea / Batmana u filmu Christophera Nolana, Batman: Početak. Bila je to obnova serijala bez poveznica s ...
pedicellata Species Bersama swynnertonii Bretschneidera sinensis Brucea macrocarpa Bulnesia carrapo Dipteronia dyeriana ...
Their collection includes a 13-metre-long mosasaur, approximately 80 million years old named Bruce - a Guinness Record holder ...
This is partly explained by the loyalty of Sir Neil Campbell (Niall mac Caile), (d.1315), to the cause of Robert the Bruce - a ...
2009 Atteva brucea - Moore, 1859 (synonym of Atteva fabriciella) Atteva niviguttella - Walker, 1863 (synonym of Atteva ...
A Tale of the Golden West Guy Boothby A Brighton Tragedy In Spite of the Czar The Stolen Peer Mary Grant Bruce - A Little Bush ...
... erythraeae Chiov. Brucea guineensis G.Don Brucea javanica (L.) Merr. Brucea macrocarpa Stannard Brucea mollis Wall. ex ... Brucea tonkinensis (Lecomte) Gagnep. Brucea trichotoma Spreng. "Genus: Brucea J.F.Mill". Germplasm Resources Information ... It contains the following species (this list may be incomplete): Brucea antidysenterica J.F.Mill. Brucea bruceadelpha (Noot.) ... Brucea is a genus of plant in the family Simaroubaceae. It is named for the Scottish scholar and explorer James Bruce. ...
Uz pomoć svoje bivše vjerenice, njenog muža Walta i fizio-terapeuta Brucea, Johnny počinje koristiti svoje moći pri rješavanju ...
... is a species of plant in the Simaroubaceae family. It is endemic to Kenya, and is being threatened by habitat ... Brucea macrocarpa. 2006 IUCN Red List of Threatened Species. Downloaded on 20 August 2007.. ...
"Brucea javanica (L.) Merr". The Plant List. Retrieved 20 March 2015. "Brucea javanica". Germplasm Resources Information Network ... Brucea javanica grows up as a shrub or small tree to 5 metres (20 ft) tall. The tiny flowers (1.5--2 mm in diameter) are ... Brucea javanica (also known as Macassar kernels) is a shrub in the family Simaroubaceae. The specific epithet javanica is from ... The fruit Brucea javanica was first written about as medicine in the Chinese medical monograph Omissions from the Grand Materia ...
... operné vokály Roba Halforda z Judas Priest a Brucea Dickinsona z Iron Maiden, chrapľavé hlasy Lemmyho z Motörhead a Jamesa ...
... i gitarist E Street Banda Brucea Springsteena.[1] Glazba je obično birana kad bi produkcija i montaža epizode bili dovršeni, ...
Brucea erythraeae Chiov. Brucea guineensis G.Don Brucea javanica (L.) Merr. Brucea macrocarpa Stannard Brucea mollis Wall. ex ... Brucea tonkinensis (Lecomte) Gagnep. Brucea trichotoma Spreng. "Genus: Brucea J.F.Mill". Germplasm Resources Information ... It contains the following species (this list may be incomplete): Brucea antidysenterica J.F.Mill. Brucea bruceadelpha (Noot.) ... Brucea is a genus of plant in the family Simaroubaceae. It is named for the Scottish scholar and explorer James Bruce. ...
Brucea macrocarpa is a species of plant in the Simaroubaceae family. It is endemic to Kenya, and is being threatened by habitat ... Brucea macrocarpa. 2006 IUCN Red List of Threatened Species. Downloaded on 20 August 2007.. ...
Seed oil of Brucea javanica (BJO) is extracted from the seeds of herb medicine Brucea javanica (L.), and its emulsion ... Seed Oil of Brucea javanica Induces Apoptotic Death of Acute Myeloid Leukemia Cells via Both the Death Receptors and the ...
BruceA is a member of Creative Writing Forums - Writing Help, Writing Workshops, & Writing Community. Active Member, Male, from ... BruceA. Active Member, Male, from France Ive been away doing creative things with wool (http://facebook.com/Felt.Buzz) but SS ...
... the Brucea Javanica oil extracted with supercritical CO2 agreed with the quality standard of refined Brucea Javanica oil for ... The technics of supercritical carbon dioxide extraction of Brucea Javanica for injection oil was studied. The effects of the ... Study on the supercritical carbon dioxide extraction of Brucea Javanica oil].. *. Fa-huan Ge, Hua-Ping Lei ... The technics of supercritical carbon dioxide extraction of Brucea Javanica for injection oil was studied. The effects of the ...
Nutrients in Brucea Antidysenterica. List of various diseases cured by Brucea Antidysenterica. How Brucea Antidysenterica is ... Names of Brucea Antidysenterica in various languages of the world are also given. ... Brucea Antidysenterica is a tree.. It is perennial.. It grows in a tropical climate.. It grows up to 9 M.. Best used for ... Side Effects, Risk Factors of, and Cautions for Brucea Antidysenterica. Avoid use during Pregnancy, Breast Feeding. ...
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Brucea javanica (Linn.)Merr. : a potent anticancer and antimalarial plant : a review. Highly accessed article. SC Sharma, VK ...
Ailanthus, Amaroria, Brucea, Castela, Eurycoma, Gymnostemon, Hannoa, Laumoniera, Leitneria, Nothospondias, Odyendea, Perriera, ... Ailanthus, Amaroria, Brucea, Castela, Eurycoma, Gymnostemon, Hannoa, Iridosma, Laumoniera, Leitneria, Nothospondias, Odyendea, ... Aeschrion, Ailanthus, Ailantus, Amaroria, Aruba (Simaroubaceae), Aylanthus, Biporeia, Brasiliastrum, Brucea, Cardiocarpus ( ... Ailanthus, Amaroria, Brucea, Castela, Eurycoma, Gymnostemon, Hannoa, Harrisonia, Holacantha, Leitneria, Nothospondias, ...
Brucea amarissima Desv. ex Gomes, B. sumatrana Roxb., Gonus amarissimus Lour., Lussa amarissima O. Ktze (2, 3). ... Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruit, Simarouba amara stem, and a number of ... In vitro antimalarial activity of Brucea javanica against multi-drug resistant Plasmodium falciparum. Planta medica, 1986, 2: ... A report on three cases of anaphylaxis caused by external application of the fruit of Brucea javanica. Bulletin of the Chinese ...
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The alginate-carrageenan-Brucea javanica oil beads had a porous structure and exhibited up to 24 h of in vitro floatability ... Formulation development and evaluation of gastroretentive floating beads with Brucea javan Formulation development and ... In the present study, a gastric retention floating system for Brucea javanica oil, composed of alginate and carrageenan, was ... Alginates , Chemistry , Animals , Biological Availability , Brucea , Chemistry , Carrageenan , Chemistry , Delayed-Action ...
Brucea javanica oil emulsion group and a Brucea javanica oil emulsion group in the presence or absence of 3-methyl adenine (3- ... Effect of Brucea javanica oil emulsion on proliferation, migration and autophagy of non-small cell lung cancer A549 cells and ... Brucea javanica oil emulsion can promote the autophagy of non-small cell lung cancer A549 cells and inhibit the cell ... A549 Cells , Autophagy , Brucea , Chemistry , Carcinoma, Non-Small-Cell Lung , Cell Movement , Cell Proliferation , Humans , ...
Brucea antidysenterica. Waginos. Simaroubaceae. Brucea abyssinica Spreng. Brucea ferruginea LH?r. Brucea salutaris A.Chev.. 1 ...
I Anchusa officinalis: Production of Rosmarinic Acid in Perfusion Cell Cultures.- II Brucea spp.: In Vitro Culture and the ... Brucea, Catharanthus, Chrysanthemum, Coleus, Corydalis, Coreopsis, Emilia, Ginkgo, Gloriosa, Hypericum, Inonotus, Leucosceptrum ...
Compare: Nux Vomica Nux; Ruta Graveolens Ruta; Merc Viv Mercur.; Brucea. - Bark of Nux Vomica Nux Vomica or angustura falsa ( ...
μg/mL, respectively (Table 1). Brucea sp. also exhibited strong potency against ORL-48 cells at μg/mL. The other two extracts ... Based on the IC50 value, the extract of Brucea sp. exhibited antiproliferative activity on KB cells at μg/mL while some ... Figure 1: Responses of KB cells to 100 μg/mL extract of (a) Brucea sp., (b) Azadirachta sp., and (c) Typhonium sp. monitored ... As anticipated with the strong antiproliferative activity of Brucea sp., the population of green spots in images of Brucea- ...
Bruce A. Burns Profile by Martindale-Hubbell. Find Bruce A. Burns contact information, experience and credentials, peer review ratings etc.
The clinical and research interests of Bruce A. Levy, M.D., focus on complex knee and hip trauma with a particular emphasis on knee dislocation, multiple ligament knee reconstruction, primary and revision ACL reconstruction, meniscal repair and transplantation as well as hip arthroscopy for labral tears and femoro-acetabular impingement (FAI).. Dr. Levy helps patients of all activity levels from professional to recreational with knee and hip injuries return to activities they enjoy through open and arthroscopic surgery using minimally invasive techniques, education and physical rehabilitation.. He has served on the AAOS Clinical Practice Guidelines Committee and is a principal investigator for several multicenter trials funded by the National Institutes of Health and Department of Defense. Dr. Levy is on the editorial board for several journals, served on the Board of Trustees for the Journal Arthroscopy and is the Sports Medicine Deputy Editor for Clinical Orthopaedics and Related Research. He ...
Wang-K; Bruce-A; Mezan-R; Kadiyala-A; Wang-L; Dawson-J; Rojanasakul-Y; Yang-Y ...
Sharp Centre Pictureby BruceA1/320. Sharp cheddar cheese with slices Picturesby BWFolsom4/71. Sharp pointed agave plant leaves ...
Choi, Y. W., Hodgkiss, I. J., & Hyde, K. D. (2005). Enzyme production by endophytes of Brucea javanica. Journal of Agricultural ...
Dr. Shapiro directs research on computational and experimental RNA structure prediction and analysis and has pioneered research in the emerging field of RNA nanobiology. His work has led to several novel RNA folding and analysis algorithms, experimental techniques and discoveries in RNA biology. His interests include RNA nanobiology, nucleic acid structure prediction and
Bruce A Kaufman, MD is a specialist in Neurosurgery, Pediatric who can be reached at (414) 266-6435, (877) 607-5280 (appointment) and whose practice locations include: Milwaukee
Quassinoids in Brucea javanica are potent stimulators of lipolysis in adipocytes.. Lahrita L, Moriai K, Iwata R, Itoh K, Kato E ...
  • DNA fragments harvested from Brucea -treated cells produced bands in a ladder pattern suggesting the apoptotic effect of the extract. (hindawi.com)
  • Ponovna uprizoritev video performansa Brucea Naumana z naslovom Walking in an exaggerated manner in the parameters of a square (Hoja z izrazitimi gibi po stranicah kvadrata), iz leta 1968, je poskus Hoffnerjeve da reartikulira odnos med telesom in prostorom v sedanjem času. (cityofwomen.org)
  • Brucea javanica, Azadirachta indica, and Typhonium flagelliforme are medicinal plants commonly used to treat conditions associated with tumour formation. (hindawi.com)