Syndrome: A characteristic symptom complex.Adipose Tissue, Brown: A thermogenic form of adipose tissue composed of BROWN ADIPOCYTES. It is found in newborns of many species including humans, and in hibernating mammals. Brown fat is richly vascularized, innervated, and densely packed with MITOCHONDRIA which can generate heat directly from the stored lipids.Adipocytes, Brown: Fat cells with dark coloration due to the densely packed MITOCHONDRIA. They contain numerous small lipid droplets or vacuoles. Their stored lipids can be converted directly to energy as heat by the mitochondria.Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)Metabolic Syndrome X: A cluster of metabolic risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome X include excess ABDOMINAL FAT; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. (from AHA/NHLBI/ADA Conference Proceedings, Circulation 2004; 109:551-556)Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.Sjogren's Syndrome: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.Phaeophyta: A division of predominantly marine EUKARYOTA, commonly known as brown algae, having CHROMATOPHORES containing carotenoid PIGMENTS, BIOLOGICAL. ALGINATES and phlorotannins occur widely in all major orders. They are considered the most highly evolved algae because of their well-developed multicellular organization and structural complexity.Turner Syndrome: A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.Rats, Inbred BNAbnormalities, MultipleThermogenesis: The generation of heat in order to maintain body temperature. The uncoupled oxidation of fatty acids contained within brown adipose tissue and SHIVERING are examples of thermogenesis in MAMMALS.Myelodysplastic Syndromes: Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA.Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.Polycystic Ovary Syndrome: A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.Williams Syndrome: A disorder caused by hemizygous microdeletion of about 28 genes on chromosome 7q11.23, including the ELASTIN gene. Clinical manifestations include SUPRAVALVULAR AORTIC STENOSIS; MENTAL RETARDATION; elfin facies; impaired visuospatial constructive abilities; and transient HYPERCALCEMIA in infancy. The condition affects both sexes, with onset at birth or in early infancy.DiGeorge Syndrome: Congenital syndrome characterized by a wide spectrum of characteristics including the absence of the THYMUS and PARATHYROID GLANDS resulting in T-cell immunodeficiency, HYPOCALCEMIA, defects in the outflow tract of the heart, and craniofacial anomalies.Horner Syndrome: A syndrome associated with defective sympathetic innervation to one side of the face, including the eye. Clinical features include MIOSIS; mild BLEPHAROPTOSIS; and hemifacial ANHIDROSIS (decreased sweating)(see HYPOHIDROSIS). Lesions of the BRAIN STEM; cervical SPINAL CORD; first thoracic nerve root; apex of the LUNG; CAROTID ARTERY; CAVERNOUS SINUS; and apex of the ORBIT may cause this condition. (From Miller et al., Clinical Neuro-Ophthalmology, 4th ed, pp500-11)Prader-Willi Syndrome: An autosomal dominant disorder caused by deletion of the proximal long arm of the paternal chromosome 15 (15q11-q13) or by inheritance of both of the pair of chromosomes 15 from the mother (UNIPARENTAL DISOMY) which are imprinted (GENETIC IMPRINTING) and hence silenced. Clinical manifestations include MENTAL RETARDATION; MUSCULAR HYPOTONIA; HYPERPHAGIA; OBESITY; short stature; HYPOGONADISM; STRABISMUS; and HYPERSOMNOLENCE. (Menkes, Textbook of Child Neurology, 5th ed, p229)Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.Guillain-Barre Syndrome: An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)Hemolytic-Uremic Syndrome: A syndrome that is associated with microvascular diseases of the KIDNEY, such as RENAL CORTICAL NECROSIS. It is characterized by hemolytic anemia (ANEMIA, HEMOLYTIC); THROMBOCYTOPENIA; and ACUTE RENAL FAILURE.Compartment Syndromes: Conditions in which increased pressure within a limited space compromises the BLOOD CIRCULATION and function of tissue within that space. Some of the causes of increased pressure are TRAUMA, tight dressings, HEMORRHAGE, and exercise. Sequelae include nerve compression (NERVE COMPRESSION SYNDROMES); PARALYSIS; and ISCHEMIC CONTRACTURE.Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or a another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)Antiphospholipid Syndrome: The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).Mitochondrial Proteins: Proteins encoded by the mitochondrial genome or proteins encoded by the nuclear genome that are imported to and resident in the MITOCHONDRIA.Porcine Reproductive and Respiratory Syndrome: A syndrome characterized by outbreaks of late term abortions, high numbers of stillbirths and mummified or weak newborn piglets, and respiratory disease in young unweaned and weaned pigs. It is caused by PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS. (Radostits et al., Veterinary Medicine, 8th ed, p1048)Klinefelter Syndrome: A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.).Carpal Tunnel Syndrome: Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)Werner Syndrome: An autosomal recessive disorder that causes premature aging in adults, characterized by sclerodermal skin changes, cataracts, subcutaneous calcification, muscular atrophy, a tendency to diabetes mellitus, aged appearance of the face, baldness, and a high incidence of neoplastic disease.Reye Syndrome: A form of encephalopathy with fatty infiltration of the LIVER, characterized by brain EDEMA and VOMITING that may rapidly progress to SEIZURES; COMA; and DEATH. It is caused by a generalized loss of mitochondrial function leading to disturbances in fatty acid and CARNITINE metabolism.Cold Temperature: An absence of warmth or heat or a temperature notably below an accustomed norm.Bartter Syndrome: A group of disorders caused by defective salt reabsorption in the ascending LOOP OF HENLE. It is characterized by severe salt-wasting, HYPOKALEMIA; HYPERCALCIURIA; metabolic ALKALOSIS, and hyper-reninemic HYPERALDOSTERONISM without HYPERTENSION. There are several subtypes including ones due to mutations in the renal specific SODIUM-POTASSIUM-CHLORIDE SYMPORTERS.Porcine respiratory and reproductive syndrome virus: A species of ARTERIVIRUS causing reproductive and respiratory disease in pigs. The European strain is called Lelystad virus. Airborne transmission is common.HELLP Syndrome: A syndrome of HEMOLYSIS, elevated liver ENZYMES, and low blood platelets count (THROMBOCYTOPENIA). HELLP syndrome is observed in pregnant women with PRE-ECLAMPSIA or ECLAMPSIA who also exhibit LIVER damage and abnormalities in BLOOD COAGULATION.Bloom Syndrome: An autosomal recessive disorder characterized by telangiectatic ERYTHEMA of the face, photosensitivity, DWARFISM and other abnormalities, and a predisposition toward developing cancer. The Bloom syndrome gene (BLM) encodes a RecQ-like DNA helicase.Brugada Syndrome: An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.Ehlers-Danlos Syndrome: A heterogeneous group of autosomally inherited COLLAGEN DISEASES caused by defects in the synthesis or structure of FIBRILLAR COLLAGEN. There are numerous subtypes: classical, hypermobility, vascular, and others. Common clinical features include hyperextensible skin and joints, skin fragility and reduced wound healing capability.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Respiratory Distress Syndrome, Adult: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Angelman Syndrome: A syndrome characterized by multiple abnormalities, MENTAL RETARDATION, and movement disorders. Present usually are skull and other abnormalities, frequent infantile spasms (SPASMS, INFANTILE); easily provoked and prolonged paroxysms of laughter (hence "happy"); jerky puppetlike movements (hence "puppet"); continuous tongue protrusion; motor retardation; ATAXIA; MUSCLE HYPOTONIA; and a peculiar facies. It is associated with maternal deletions of chromosome 15q11-13 and other genetic abnormalities. (From Am J Med Genet 1998 Dec 4;80(4):385-90; Hum Mol Genet 1999 Jan;8(1):129-35)Pedigree: The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.Severe Acute Respiratory Syndrome: A viral disorder characterized by high FEVER, dry COUGH, shortness of breath (DYSPNEA) or breathing difficulties, and atypical PNEUMONIA. A virus in the genus CORONAVIRUS is the suspected agent.Restless Legs Syndrome: A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep.Job Syndrome: Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.Wiskott-Aldrich Syndrome: A rare, X-linked immunodeficiency syndrome characterized by ECZEMA; LYMPHOPENIA; and, recurrent pyogenic infection. It is seen exclusively in young boys. Typically, IMMUNOGLOBULIN M levels are low and IMMUNOGLOBULIN A and IMMUNOGLOBULIN E levels are elevated. Lymphoreticular malignancies are common.Paraneoplastic Syndromes: In patients with neoplastic diseases a wide variety of clinical pictures which are indirect and usually remote effects produced by tumor cell metabolites or other products.Brown Recluse Spider: A spider of the genus Loxosceles, found in the midwestern and other parts of the United States, which carries a hemolytic venom that produces local necrosis or ulceration.Sweet Syndrome: Condition characterized by large, rapidly extending, erythematous, tender plaques on the upper body usually accompanied by fever and dermal infiltration of neutrophilic leukocytes. It occurs mostly in middle-aged women, is often preceded by an upper respiratory infection, and clinically resembles ERYTHEMA MULTIFORME. Sweet syndrome is associated with LEUKEMIA.Adipose Tissue, White: Fatty tissue composed of WHITE ADIPOCYTES and generally found directly under the skin (SUBCUTANEOUS FAT) and around the internal organs (ABDOMINAL FAT). It has less vascularization and less coloration than the BROWN FAT. White fat provides heat insulation, mechanical cushion, and source of energy.Body Temperature Regulation: The processes of heating and cooling that an organism uses to control its temperature.Ion Channels: Gated, ion-selective glycoproteins that traverse membranes. The stimulus for ION CHANNEL GATING can be due to a variety of stimuli such as LIGANDS, a TRANSMEMBRANE POTENTIAL DIFFERENCE, mechanical deformation or through INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)Churg-Strauss Syndrome: Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA.Trout: Various fish of the family SALMONIDAE, usually smaller than salmon. They are mostly restricted to cool clear freshwater. Some are anadromous. They are highly regarded for their handsome colors, rich well-flavored flesh, and gameness as an angling fish. The genera Salvelinus, Salmo, and ONCORHYNCHUS have been introduced virtually throughout the world.Sturge-Weber Syndrome: A non-inherited congenital condition with vascular and neurological abnormalities. It is characterized by facial vascular nevi (PORT-WINE STAIN), and capillary angiomatosis of intracranial membranes (MENINGES; CHOROID). Neurological features include EPILEPSY; cognitive deficits; GLAUCOMA; and visual defects.Adipocytes, White: Fat cells with light coloration and few MITOCHONDRIA. They contain a scant ring of CYTOPLASM surrounding a single large lipid droplet or vacuole.Budd-Chiari Syndrome: A condition in which the hepatic venous outflow is obstructed anywhere from the small HEPATIC VEINS to the junction of the INFERIOR VENA CAVA and the RIGHT ATRIUM. Usually the blockage is extrahepatic and caused by blood clots (THROMBUS) or fibrous webs. Parenchymal FIBROSIS is uncommon.Chediak-Higashi Syndrome: A form of phagocyte bactericidal dysfunction characterized by unusual oculocutaneous albinism, high incidence of lymphoreticular neoplasms, and recurrent pyogenic infections. In many cell types, abnormal lysosomes are present leading to defective pigment distribution and abnormal neutrophil functions. The disease is transmitted by autosomal recessive inheritance and a similar disorder occurs in the beige mouse, the Aleutian mink, and albino Hereford cattle.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Wolff-Parkinson-White Syndrome: A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.Facies: The appearance of the face that is often characteristic of a disease or pathological condition, as the elfin facies of WILLIAMS SYNDROME or the mongoloid facies of DOWN SYNDROME. (Random House Unabridged Dictionary, 2d ed)Kallmann Syndrome: A genetically heterogeneous disorder caused by hypothalamic GNRH deficiency and OLFACTORY NERVE defects. It is characterized by congenital HYPOGONADOTROPIC HYPOGONADISM and ANOSMIA, possibly with additional midline defects. It can be transmitted as an X-linked (GENETIC DISEASES, X-LINKED), an autosomal dominant, or an autosomal recessive trait.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Sick Sinus Syndrome: A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.Sezary Syndrome: A form of cutaneous T-cell lymphoma manifested by generalized exfoliative ERYTHRODERMA; PRURITUS; peripheral lymphadenopathy, and abnormal hyperchromatic mononuclear (cerebriform) cells in the skin, LYMPH NODES, and peripheral blood (Sezary cells).Felty Syndrome: A rare complication of rheumatoid arthritis with autoimmune NEUTROPENIA; and SPLENOMEGALY.Usher Syndromes: Autosomal recessive hereditary disorders characterized by congenital SENSORINEURAL HEARING LOSS and RETINITIS PIGMENTOSA. Genetically and symptomatically heterogeneous, clinical classes include type I, type II, and type III. Their severity, age of onset of retinitis pigmentosa and the degree of vestibular dysfunction are variable.Sargassum: One of the largest genera of BROWN ALGAE, comprised of more than 150 species found in tropical, subtropical, and temperate zones of both hemispheres. Some species are attached (benthic) but most float in the open sea (pelagic). Sargassum provides a critical habitat for hundreds of species of FISHES; TURTLES; and INVERTEBRATES.Beckwith-Wiedemann Syndrome: A syndrome of multiple defects characterized primarily by umbilical hernia (HERNIA, UMBILICAL); MACROGLOSSIA; and GIGANTISM; and secondarily by visceromegaly; HYPOGLYCEMIA; and ear abnormalities.Seaweed: Multicellular marine macroalgae including some members of red (RHODOPHYTA), green (CHLOROPHYTA), and brown (PHAEOPHYTA) algae. They are widely distributed in the ocean, occurring from the tide level to considerable depths, free-floating (planktonic) or anchored to the substratum (benthic). They lack a specialized vascular system but take up fluids, nutrients, and gases directly from the water. They contain CHLOROPHYLL and are photosynthetic, but some also contain other light-absorbing pigments. Many are of economic importance as FOOD, fertilizer, AGAR, potash, or source of IODINE.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Hares: The genus Lepus, in the family Leporidae, order LAGOMORPHA. Hares are born above ground, fully furred, and with their eyes and ears open. In contrast with RABBITS, hares have 24 chromosome pairs.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Alagille Syndrome: A multisystem disorder that is characterized by aplasia of intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC), and malformations in the cardiovascular system, the eyes, the vertebral column, and the facies. Major clinical features include JAUNDICE, and congenital heart disease with peripheral PULMONARY STENOSIS. Alagille syndrome may result from heterogeneous gene mutations, including mutations in JAG1 on CHROMOSOME 20 (Type 1) and NOTCH2 on CHROMOSOME 1 (Type 2).Fucus: A genus of BROWN ALGAE in the family Fucaceae. It is found in temperate, marine intertidal areas along rocky coasts and is a source of ALGINATES. Some species of Fucus are referred to as KELP.Bardet-Biedl Syndrome: An autosomal recessive disorder characterized by RETINITIS PIGMENTOSA; POLYDACTYLY; OBESITY; MENTAL RETARDATION; hypogenitalism; renal dysplasia; and short stature. This syndrome has been distinguished as a separate entity from LAURENCE-MOON SYNDROME. (From J Med Genet 1997 Feb;34(2):92-8)Peutz-Jeghers Syndrome: A hereditary disease caused by autosomal dominant mutations involving CHROMOSOME 19. It is characterized by the presence of INTESTINAL POLYPS, consistently in the JEJUNUM, and mucocutaneous pigmentation with MELANIN spots of the lips, buccal MUCOSA, and digits.Hemorrhagic Fever with Renal Syndrome: An acute febrile disease occurring predominately in Asia. It is characterized by fever, prostration, vomiting, hemorrhagic phenonema, shock, and renal failure. It is caused by any one of several closely related species of the genus Hantavirus. The most severe form is caused by HANTAAN VIRUS whose natural host is the rodent Apodemus agrarius. Milder forms are caused by SEOUL VIRUS and transmitted by the rodents Rattus rattus and R. norvegicus, and the PUUMALA VIRUS with transmission by Clethrionomys galreolus.Oculocerebrorenal Syndrome: A sex-linked recessive disorder affecting multiple systems including the EYE, the NERVOUS SYSTEM, and the KIDNEY. Clinical features include congenital CATARACT; MENTAL RETARDATION; and renal tubular dysfunction (FANCONI SYNDROME; RENAL TUBULAR ACIDOSIS; X-LINKED HYPOPHOSPHATEMIA or vitamin-D-resistant rickets) and SCOLIOSIS. This condition is due to a deficiency of phosphatidylinositol 4,5-bisphosphate-5-phosphatase leading to defects in PHOSPHATIDYLINOSITOL metabolism and INOSITOL signaling pathway. (from Menkes, Textbook of Child Neurology, 5th ed, p60; Am J Hum Genet 1997 Jun;60(6):1384-8)Obesity: A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).Cockayne Syndrome: A syndrome characterized by multiple system abnormalities including DWARFISM; PHOTOSENSITIVITY DISORDERS; PREMATURE AGING; and HEARING LOSS. It is caused by mutations of a number of autosomal recessive genes encoding proteins that involve transcriptional-coupled DNA REPAIR processes. Cockayne syndrome is classified by the severity and age of onset. Type I (classical; CSA) is early childhood onset in the second year of life; type II (congenital; CSB) is early onset at birth with severe symptoms; type III (xeroderma pigmentosum; XP) is late childhood onset with mild symptoms.Smith-Lemli-Opitz Syndrome: An autosomal recessive disorder of CHOLESTEROL metabolism. It is caused by a deficiency of 7-dehydrocholesterol reductase, the enzyme that converts 7-dehydrocholesterol to cholesterol, leading to an abnormally low plasma cholesterol. This syndrome is characterized by multiple CONGENITAL ABNORMALITIES, growth deficiency, and INTELLECTUAL DISABILITY.Adipocytes: Cells in the body that store FATS, usually in the form of TRIGLYCERIDES. WHITE ADIPOCYTES are the predominant type and found mostly in the abdominal cavity and subcutaneous tissue. BROWN ADIPOCYTES are thermogenic cells that can be found in newborns of some species and hibernating mammals.Infant, Newborn: An infant during the first month after birth.Wiskott-Aldrich Syndrome Protein: WASP protein is mutated in WISKOTT-ALDRICH SYNDROME and is expressed primarily in hematopoietic cells. It is the founding member of the WASP protein family and interacts with CDC42 PROTEIN to help regulate ACTIN polymerization.Stiff-Person Syndrome: A condition characterized by persistent spasms (SPASM) involving multiple muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as noise and light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. Respiration may become impaired in advanced cases. (Adams et al., Principles of Neurology, 6th ed, p1492; Neurology 1998 Jul;51(1):85-93)Short Bowel Syndrome: A malabsorption syndrome resulting from extensive operative resection of the SMALL INTESTINE, the absorptive region of the GASTROINTESTINAL TRACT.Behcet Syndrome: Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.Zollinger-Ellison Syndrome: A syndrome that is characterized by the triad of severe PEPTIC ULCER, hypersecretion of GASTRIC ACID, and GASTRIN-producing tumors of the PANCREAS or other tissue (GASTRINOMA). This syndrome may be sporadic or be associated with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1.Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Hepatopulmonary Syndrome: A syndrome characterized by the clinical triad of advanced chronic liver disease, pulmonary vascular dilatations, and reduced arterial oxygenation (HYPOXEMIA) in the absence of intrinsic cardiopulmonary disease. This syndrome is common in the patients with LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL).Orofaciodigital Syndromes: Two syndromes of oral, facial, and digital malformations. Type I (Papillon-Leage and Psaume syndrome, Gorlin-Psaume syndrome) is inherited as an X-linked dominant trait and is found only in females and XXY males. Type II (Mohr syndrome) is inherited as an autosomal recessive trait.Receptors, Adrenergic, beta-3: A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The beta-3 adrenergic receptors are the predominant beta-adrenergic receptor type expressed in white and brown ADIPOCYTES and are involved in modulating ENERGY METABOLISM and THERMOGENESIS.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Proteus Syndrome: Hamartoneoplastic malformation syndrome of uncertain etiology characterized by partial GIGANTISM of the hands and/or feet, asymmetry of the limbs, plantar hyperplasia, hemangiomas (HEMANGIOMA), lipomas (LIPOMA), lymphangiomas (LYMPHANGIOMA), epidermal NEVI; MACROCEPHALY; cranial HYPEROSTOSIS, and long-bone overgrowth. Joseph Merrick, the so-called "elephant man", apparently suffered from Proteus syndrome and not NEUROFIBROMATOSIS, a disorder with similar characteristics.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Duane Retraction Syndrome: A syndrome characterized by marked limitation of abduction of the eye, variable limitation of adduction and retraction of the globe, and narrowing of the palpebral fissure on attempted adduction. The condition is caused by aberrant innervation of the lateral rectus by fibers of the OCULOMOTOR NERVE.Immunologic Deficiency Syndromes: Syndromes in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Adipose Tissue: Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white.DNA Mutational Analysis: Biochemical identification of mutational changes in a nucleotide sequence.Carrier Proteins: Transport proteins that carry specific substances in the blood or across cell membranes.Complex Regional Pain Syndromes: Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)Goldenhar Syndrome: Mandibulofacial dysostosis with congenital eyelid dermoids.Respiratory Distress Syndrome, Newborn: A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause.Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)Costello Syndrome: Rare congenital disorder with multiple anomalies including: characteristic dysmorphic craniofacial features, musculoskeletal abnormalities, neurocognitive delay, and high prevalence of cancer. Germline mutations in H-Ras protein can cause Costello syndrome. Costello syndrome shows early phenotypic overlap with other disorders that involve MAP KINASE SIGNALING SYSTEM (e.g., NOONAN SYNDROME and cardiofaciocutaneous syndrome).Klippel-Feil Syndrome: A syndrome characterised by a low hairline and a shortened neck resulting from a reduced number of vertebrae or the fusion of multiple hemivertebrae into one osseous mass.Subclavian Steal Syndrome: A clinically significant reduction in blood supply to the BRAIN STEM and CEREBELLUM (i.e., VERTEBROBASILAR INSUFFICIENCY) resulting from reversal of blood flow through the VERTEBRAL ARTERY from occlusion or stenosis of the proximal subclavian or brachiocephalic artery. Common symptoms include VERTIGO; SYNCOPE; and INTERMITTENT CLAUDICATION of the involved upper extremity. Subclavian steal may also occur in asymptomatic individuals. (From J Cardiovasc Surg 1994;35(1):11-4; Acta Neurol Scand 1994;90(3):174-8)Hantavirus Pulmonary Syndrome: Acute respiratory illness in humans caused by the Muerto Canyon virus whose primary rodent reservoir is the deer mouse Peromyscus maniculatus. First identified in the southwestern United States, this syndrome is characterized most commonly by fever, myalgias, headache, cough, and rapid respiratory failure.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Neoplastic Syndromes, Hereditary: The condition of a pattern of malignancies within a family, but not every individual's necessarily having the same neoplasm. Characteristically the tumor tends to occur at an earlier than average age, individuals may have more than one primary tumor, the tumors may be multicentric, usually more than 25 percent of the individuals in direct lineal descent from the proband are affected, and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance.Thoracic Outlet Syndrome: A neurovascular syndrome associated with compression of the BRACHIAL PLEXUS; SUBCLAVIAN ARTERY; and SUBCLAVIAN VEIN at the superior thoracic outlet. This may result from a variety of anomalies such as a CERVICAL RIB, anomalous fascial bands, and abnormalities of the origin or insertion of the anterior or medial scalene muscles. Clinical features may include pain in the shoulder and neck region which radiates into the arm, PARESIS or PARALYSIS of brachial plexus innervated muscles, PARESTHESIA, loss of sensation, reduction of arterial pulses in the affected extremity, ISCHEMIA, and EDEMA. (Adams et al., Principles of Neurology, 6th ed, pp214-5).Hermanski-Pudlak Syndrome: Syndrome characterized by the triad of oculocutaneous albinism (ALBINISM, OCULOCUTANEOUS); PLATELET STORAGE POOL DEFICIENCY; and lysosomal accumulation of ceroid lipofuscin.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.White spot syndrome virus 1: A species of DNA virus, in the genus WHISPOVIRUS, infecting PENAEID SHRIMP.LEOPARD Syndrome: An autosomal dominant disorder with an acronym of its seven features (LENTIGO; ELECTROCARDIOGRAM abnormalities; ocular HYPERTELORISM; PULMONARY STENOSIS; abnormal genitalia; retardation of growth; and DEAFNESS or SENSORINEURAL HEARING LOSS). This syndrome is caused by mutations of PTPN11 gene encoding the non-receptor PROTEIN TYROSINE PHOSPHATASE, type 11, and is an allelic to NOONAN SYNDROME. Features of LEOPARD syndrome overlap with those of NEUROFIBROMATOSIS 1 which is caused by mutations in the NEUROFIBROMATOSIS 1 GENES.Hand Deformities, Congenital: Alterations or deviations from normal shape or size which result in a disfigurement of the hand occurring at or before birth.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Eye Abnormalities: Congenital absence of or defects in structures of the eye; may also be hereditary.Li-Fraumeni Syndrome: Rare autosomal dominant syndrome characterized by mesenchymal and epithelial neoplasms at multiple sites. MUTATION of the p53 tumor suppressor gene, a component of the DNA DAMAGE response pathway, apparently predisposes family members who inherit it to develop certain cancers. The spectrum of cancers in the syndrome was shown to include, in addition to BREAST CANCER and soft tissue sarcomas (SARCOMA); BRAIN TUMORS; OSTEOSARCOMA; LEUKEMIA; and ADRENOCORTICAL CARCINOMA.Hamartoma Syndrome, Multiple: A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE.Asperger Syndrome: A disorder beginning in childhood whose essential features are persistent impairment in reciprocal social communication and social interaction, and restricted, repetitive patterns of behavior, interests, or activities. These symptoms may limit or impair everyday functioning. (From DSM-5)Chiroptera: Order of mammals whose members are adapted for flight. It includes bats, flying foxes, and fruit bats.Mobius Syndrome: A syndrome of congenital facial paralysis, frequently associated with abducens palsy and other congenital abnormalities including lingual palsy, clubfeet, brachial disorders, cognitive deficits, and pectoral muscle defects. Pathologic findings are variable and include brain stem nuclear aplasia, facial nerve aplasia, and facial muscle aplasia, consistent with a multifactorial etiology. (Adams et al., Principles of Neurology, 6th ed, p1020)Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Hepatorenal Syndrome: Functional KIDNEY FAILURE in patients with liver disease, usually LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL), and in the absence of intrinsic renal disease or kidney abnormality. It is characterized by intense renal vasculature constriction, reduced renal blood flow, OLIGURIA, and sodium retention.Waardenburg Syndrome: Rare, autosomal dominant disease with variable penetrance and several known clinical types. Characteristics may include depigmentation of the hair and skin, congenital deafness, heterochromia iridis, medial eyebrow hyperplasia, hypertrophy of the nasal root, and especially dystopia canthorum. The underlying cause may be defective development of the neural crest (neurocristopathy). Waardenburg's syndrome may be closely related to piebaldism. Klein-Waardenburg Syndrome refers to a disorder that also includes upper limb abnormalities.Systemic Inflammatory Response Syndrome: A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA 90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.Laminaria: A genus of BROWN ALGAE in the family Laminariaceae. Dried pencil-like pieces may be inserted in the cervix where they swell as they absorb moisture, serving as osmotic dilators.Sleep Apnea Syndromes: Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Adie Syndrome: A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Polyradiculoneuropathy: Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (GUILLAIN-BARRE SYNDROME) and POLYRADICULONEUROPATHY, CHRONIC INFLAMMATORY DEMYELINATING. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots.Ovarian Hyperstimulation Syndrome: A complication of OVULATION INDUCTION in infertility treatment. It is graded by the severity of symptoms which include OVARY enlargement, multiple OVARIAN FOLLICLES; OVARIAN CYSTS; ASCITES; and generalized EDEMA. The full-blown syndrome may lead to RENAL FAILURE, respiratory distress, and even DEATH. Increased capillary permeability is caused by the vasoactive substances, such as VASCULAR ENDOTHELIAL GROWTH FACTORS, secreted by the overly-stimulated OVARIES.Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.Premenstrual Syndrome: A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses.Miller Fisher Syndrome: A variant of the GUILLAIN-BARRE SYNDROME characterized by the acute onset of oculomotor dysfunction, ataxia, and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk. The ataxia is produced by peripheral sensory nerve dysfunction and not by cerebellar injury. Facial weakness and sensory loss may also occur. The process is mediated by autoantibodies directed against a component of myelin found in peripheral nerves. (Adams et al., Principles of Neurology, 6th ed, p1313; Neurology 1987 Sep;37(9):1493-8)Capillary Leak Syndrome: A condition characterized by recurring episodes of fluid leaking from capillaries into extra-vascular compartments causing hematocrit to rise precipitously. If not treated, generalized vascular leak can lead to generalized EDEMA; SHOCK; cardiovascular collapse; and MULTIPLE ORGAN FAILURE.Acclimatization: Adaptation to a new environment or to a change in the old.Eye Color: Color of the iris.Korsakoff Syndrome: An acquired cognitive disorder characterized by inattentiveness and the inability to form short term memories. This disorder is frequently associated with chronic ALCOHOLISM; but it may also result from dietary deficiencies; CRANIOCEREBRAL TRAUMA; NEOPLASMS; CEREBROVASCULAR DISORDERS; ENCEPHALITIS; EPILEPSY; and other conditions. (Adams et al., Principles of Neurology, 6th ed, p1139)Neurocutaneous Syndromes: A group of disorders characterized by ectodermal-based malformations and neoplastic growths in the skin, nervous system, and other organs.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Gitelman Syndrome: An inherited renal disorder characterized by defective NaCl reabsorption in the convoluted DISTAL KIDNEY TUBULE leading to HYPOKALEMIA. In contrast with BARTTER SYNDROME, Gitelman syndrome includes hypomagnesemia and normocalcemic hypocalciuria, and is caused by mutations in the thiazide-sensitive SODIUM-POTASSIUM-CHLORIDE SYMPORTERS.Energy Metabolism: The chemical reactions involved in the production and utilization of various forms of energy in cells.Wolfram Syndrome: A hereditary condition characterized by multiple symptoms including those of DIABETES INSIPIDUS; DIABETES MELLITUS; OPTIC ATROPHY; and DEAFNESS. This syndrome is also known as DIDMOAD (first letter of each word) and is usually associated with VASOPRESSIN deficiency. It is caused by mutations in gene WFS1 encoding wolframin, a 100-kDa transmembrane protein.Mutation, Missense: A mutation in which a codon is mutated to one directing the incorporation of a different amino acid. This substitution may result in an inactive or unstable product. (From A Dictionary of Genetics, King & Stansfield, 5th ed)Pigmentation DisordersAcquired Hyperostosis Syndrome: Syndrome consisting of SYNOVITIS; ACNE CONGLOBATA; PALMOPLANTAR PUSTULOSIS; HYPEROSTOSIS; and OSTEITIS. The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.Mitochondria: Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.CREST Syndrome: A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. When the defect in esophageal function is not prominent, it is known as CRST syndrome.Wasting Syndrome: A condition of involuntary weight loss of greater then 10% of baseline body weight. It is characterized by atrophy of muscles and depletion of lean body mass. Wasting is a sign of MALNUTRITION as a result of inadequate dietary intake, malabsorption, or hypermetabolism.Superior Vena Cava Syndrome: A condition that occurs when the obstruction of the thin-walled SUPERIOR VENA CAVA interrupts blood flow from the head, upper extremities, and thorax to the RIGHT ATRIUM. Obstruction can be caused by NEOPLASMS; THROMBOSIS; ANEURYSM; or external compression. The syndrome is characterized by swelling and/or CYANOSIS of the face, neck, and upper arms.SARS Virus: A species of CORONAVIRUS causing atypical respiratory disease (SEVERE ACUTE RESPIRATORY SYNDROME) in humans. The organism is believed to have first emerged in Guangdong Province, China, in 2002. The natural host is the Chinese horseshoe bat, RHINOLOPHUS sinicus.Chromosomes, Human, Pair 22: A specific pair of GROUP G CHROMOSOMES of the human chromosome classification.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Munchausen Syndrome: A factitious disorder characterized by habitual presentation for hospital treatment of an apparent acute illness, the patient giving a plausible and dramatic history, all of which is false.Myasthenic Syndromes, Congenital: A heterogeneous group of disorders characterized by a congenital defect in neuromuscular transmission at the NEUROMUSCULAR JUNCTION. This includes presynaptic, synaptic, and postsynaptic disorders (that are not of autoimmune origin). The majority of these diseases are caused by mutations of various subunits of the nicotinic acetylcholine receptor (RECEPTORS, NICOTINIC) on the postsynaptic surface of the junction. (From Arch Neurol 1999 Feb;56(2):163-7)Norepinephrine: Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.Poland Syndrome: A syndrome which is characterized by symbrachydactyly and aplasia of the sternal head of pectoralis major.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Insulin: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Hemiptera: A large order of insects characterized by having the mouth parts adapted to piercing or sucking. It is comprised of four suborders: HETEROPTERA, Auchenorrhyncha, Sternorrhyncha, and Coleorrhyncha.Mice, Inbred C57BLAlstrom Syndrome: Rare autosomal recessive disease characterized by multiple organ dysfunction. The key clinical features include retinal degeneration (NYSTAGMUS, PATHOLOGIC; RETINITIS PIGMENTOSA; and eventual blindness), childhood obesity, sensorineural hearing loss, and normal mental development. Endocrinologic complications include TYPE 2 DIABETES MELLITUS; HYPERINSULINEMIA; ACANTHOSIS NIGRICANS; HYPOTHYROIDISM; and progressive renal and hepatic failures. The disease is caused by mutations in the ALMS1 gene.Rubinstein-Taybi Syndrome: A chromosomal disorder characterized by MENTAL RETARDATION, broad thumbs, webbing of fingers and toes, beaked nose, short upper lip, pouting lower lip, agenesis of corpus callosum, large foramen magnum, keloid formation, pulmonary stenosis, vertebral anomalies, chest wall anomalies, sleep apnea, and megacolon. The disease has an autosomal dominant pattern of inheritance and is associated with deletions of the short arm of chromosome 16 (16p13.3).Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Heterozygote: An individual having different alleles at one or more loci regarding a specific character.Ocular Motility Disorders: Disorders that feature impairment of eye movements as a primary manifestation of disease. These conditions may be divided into infranuclear, nuclear, and supranuclear disorders. Diseases of the eye muscles or oculomotor cranial nerves (III, IV, and VI) are considered infranuclear. Nuclear disorders are caused by disease of the oculomotor, trochlear, or abducens nuclei in the BRAIN STEM. Supranuclear disorders are produced by dysfunction of higher order sensory and motor systems that control eye movements, including neural networks in the CEREBRAL CORTEX; BASAL GANGLIA; CEREBELLUM; and BRAIN STEM. Ocular torticollis refers to a head tilt that is caused by an ocular misalignment. Opsoclonus refers to rapid, conjugate oscillations of the eyes in multiple directions, which may occur as a parainfectious or paraneoplastic condition (e.g., OPSOCLONUS-MYOCLONUS SYNDROME). (Adams et al., Principles of Neurology, 6th ed, p240)Sudden Infant Death: The abrupt and unexplained death of an apparently healthy infant under one year of age, remaining unexplained after a thorough case investigation, including performance of a complete autopsy, examination of the death scene, and review of the clinical history. (Pediatr Pathol 1991 Sep-Oct;11(5):677-84)Genes, Recessive: Genes that influence the PHENOTYPE only in the homozygous state.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Hypoplastic Left Heart Syndrome: A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Romano-Ward Syndrome: A form of long QT syndrome that is without congenital deafness. It is caused by mutation of the KCNQ1 gene which encodes a protein in the VOLTAGE-GATED POTASSIUM CHANNEL.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Acute Disease: Disease having a short and relatively severe course.Syndactyly: A congenital anomaly of the hand or foot, marked by the webbing between adjacent fingers or toes. Syndactylies are classified as complete or incomplete by the degree of joining. Syndactylies can also be simple or complex. Simple syndactyly indicates joining of only skin or soft tissue; complex syndactyly marks joining of bony elements.Microcephaly: A congenital abnormality in which the CEREBRUM is underdeveloped, the fontanels close prematurely, and, as a result, the head is small. (Desk Reference for Neuroscience, 2nd ed.)Rothmund-Thomson Syndrome: An autosomal recessive syndrome occurring principally in females, characterized by the presence of reticulated, atrophic, hyperpigmented, telangiectatic cutaneous plaques, often accompanied by juvenile cataracts, saddle nose, congenital bone defects, disturbances in the growth of HAIR; NAILS; and TEETH; and HYPOGONADISM.Adipogenesis: The differentiation of pre-adipocytes into mature ADIPOCYTES.Dwarfism: A genetic or pathological condition that is characterized by short stature and undersize. Abnormal skeletal growth usually results in an adult who is significantly below the average height.Blood Glucose: Glucose in blood.Burning Mouth Syndrome: A group of painful oral symptoms associated with a burning or similar sensation. There is usually a significant organic component with a degree of functional overlay; it is not limited to the psychophysiologic group of disorders.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Chromosome Mapping: Any method used for determining the location of and relative distances between genes on a chromosome.Chromosome Deletion: Actual loss of portion of a chromosome.Hypertelorism: Abnormal increase in the interorbital distance due to overdevelopment of the lesser wings of the sphenoid.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Idiopathic spinal cord herniation: value of MR phase-contrast imaging. (1/30)We report two patients with an idiopathic transdural spinal cord herniation at the thoracic level. Phase-contrast MR imaging was helpful in showing an absence of CSF flow ventral to the herniated cord and a normal CSF flow pattern dorsal to the cord, which excluded a compressive posterior arachnoid cyst. (+info)
High cervical disc herniation and Brown-Sequard syndrome. A case report and review of the literature. (2/30)We describe a rare herniation of the disc at the C2/C3 level in a 73-year-old woman. It caused hemicompression of the spinal cord and led to the Brown-Sequard syndrome. The condition was diagnosed clinically and by MRI six months after onset. Discectomy and fusion gave complete neurological resolution. (+info)
Cardiovascular responses to static exercise in patients with Brown-Sequard syndrome. (3/30)1. The purpose of this study was to determine the contributions of central command and the exercise pressor reflex in regulating the cardiovascular response to static exercise in patients with Brown-Sequard syndrome. In this rare condition, a hemisection of the spinal cord typically leaves one side of the body with diminished sensation and normal motor function and the other side with diminished motor function and normal sensation. 2. Four, otherwise healthy, patients with Brown-Sequard syndrome and varying degrees of motor and sensory dysfunction were studied during four isometric knee extension protocols involving both voluntary contraction and electrically stimulated contractions of each leg. Heart rate, blood pressure, force production and ratings of perceived exertion were measured during all conditions. Measurements were also made during post-contraction thigh cuff occlusion and during a cold pressor test. 3. With the exception of electrical stimulation of the leg with a sensory deficit, protocols yielded increases in heart rate and blood pressure. Cuff occlusion sustained blood pressure above resting levels only when the leg had intact sensation. 4. While voluntary contraction (or attempted contraction) of the leg with a motor deficit produced the lowest force, it produced the highest ratings of perceived exertion coupled with the greatest elevations in heart rate and blood pressure. 5. These data show that the magnitude of the heart rate and blood pressure responses in these patients was greatly affected by an increased central command; however, there were marked cardiovascular responses due to activation of the exercise pressor reflex in the absence of central command. (+info)
Traumatic invagination of the fourth and fifth cervical laminae with acute hemiparesis. (4/30)We describe a patient with traumatic right-sided invagination of two consecutive laminae into the spinal canal. The injury resembled a greenstick fracture and resulted in an acute Brown-Sequard syndrome. There was also an undisplaced hangman's fracture of the axis vertebra. These injuries were caused by an acute hyperextension and axial compression of the cervical spine. Open reduction and internal fixation of the laminar fractures without fusion was followed by full neurological recovery within six weeks. (+info)
A case of Brown-Sequard syndrome with associated Horner's syndrome after blunt injury to the cervical spine. (5/30)A 26 year old motorcyclist was received by the trauma team in our accident and emergency department after a head on collision with a motor vehicle. He had been correctly immobilised and his primary survey was essentially normal. He was alert and orientated with a Glasgow Coma score of 15 and had no symptoms or signs of spinal injury. His cervical spine radiography was also normal. Neurological examination however, revealed anisocoria, his left pupil being smaller than his right, and a Brown-Sequard syndrome, with a sensory level at C6. Immobilisation was maintained and he was transferred to the regional neurosurgical centre where magnetic resonance imaging revealed a contusion of the left half of the spinal cord adjacent to the 6th cervical vertebrae. Computed tomography revealed no bony injury but spinal column instability was demonstrated after flexion-extension spinal views and he underwent surgery to fuse his spine at the C5-C6 level. This report highlights the necessity to observe strict ATLS guidelines. This must include a thorough examination of the central and peripheral nervous system where spinal injury is suspected, even in the absence of radiographic abnormality and neck pain. This article also presents the unusual phenomena of Brown-Sequard syndrome and unilateral Horner's syndrome after blunt traumatic injury to the cervical spine. (+info)
Idiopathic spinal cord herniation associated with calcified thoracic disc extrusion--case report. (6/30)A 48-year-old man presented with idiopathic spinal cord herniation associated with calcified thoracic disc extrusion at the T7-8 intervertebral level, manifesting as Brown-Sequard syndrome at the thoracic level persisting for 20 years. Preoperative magnetic resonance imaging and computed tomography myelography revealed ventral displacement of the spinal cord and extrusion of a calcified disc at the T7-8 intervertebral level. At surgery, the spinal cord herniation at this level was released from the dura mater and carefully returned to the dural sac. An extruded calcified thoracic disc was found just below the dural defect at the same level. The development of idiopathic spinal cord herniation is associated closely with a defect in the ventral dura mater of unknown etiology. In our case, the etiology of the ventral dural defect was probably associated with the calcified thoracic disc extrusion. (+info)
Brown-Sequard syndrome after blunt cervical spine trauma: clinical and radiological correlations. (7/30)The objective of this study was to describe clinical and radiological features of a series of patients presenting with Brown-Sequard syndrome after blunt spinal trauma and to determine whether a correlation exists between cervical plain films, CT, MRI and the clinical presentation and neurological outcome. A retrospective review was done of the medical records and analysis of clinical and radiological features of patients diagnosed of BSS after blunt cervical spine trauma and admitted to our hospital between 1995 and 2005. Ten patients were collected for study, three with upper- and seven with lower-cervical spine fracture. ASIA impairment scale and motor score were determined on admission and at last follow-up (6 months-9 years, mean 30 months). Patients with lower cervical spine fracture presented with laminar fracture ipsilateral to the side of cord injury in five out of six cases. T2-weighted hyperintensity was present in seven patients showing a close correlation with neurological deficit in terms of side and level but not with the severity of motor deficit. Patients with Brown-Sequard syndrome secondary to blunt cervical spine injury commonly presented T2-weighted hyperintensity in the clinically affected hemicord. A close correlation was observed between these signal changes in the MR studies and the neurologic level. Effacement of the anterior cervical subarachnoid space was present in all patients, standing as a highly sensitive but very nonspecific finding. In the present study, craniocaudal extent of T2-weighted hyperintensity of the cord failed to demonstrate a positive correlation with neurological impairment. (+info)
Focal akinetic seizures as the only clinical manifestation of partial epilepsy. (8/30)Episodic hemipareis is usually thought to have a vascular etiology. Ictal paresis during seizures usually occurs with other clinical signs. The exact mechanism by which weakness occurs during seizures is difficult to determine as positive and negative motor phenomenona occur in rapid succession. This case describes a girl with episodic ictal hemiparesis since infancy as the only clinical seizure manifestation with VEEG suggesting mesial frontal ictal onset. (+info)
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Saxon, M; Snyder, HA; Washington, HA (1982). "Atypical Brown-Sequard syndrome following gunshot wound to the face". Journal of ...
Hancock JB, Field EM, Gadam R (1997). "Spinal epidural hematoma progressing to Brown-Sequard syndrome: report of a case". J ... Brown-Séquard syndrome (also known as Brown-Séquard's hemiplegia, Brown-Séquard's paralysis, hemiparaplegic syndrome, ... can be called a partial Brown-Séquard or incomplete Brown-Séquard syndrome. Brown-Séquard syndrome is characterized by loss of ... Lim E, Wong YS, Lo YL, Lim SH (April 2003). "Traumatic atypical Brown-Sequard syndrome: case report and literature review". ...
The New England Journal of Medicine
The neurologist would go on to describe what is now known as the Brown-Sequard syndrome. In June 1948, Sidney Farber reported ... Brown-Sequard, C.E.; Webber, S.G. (1872). "The origin and signification of the symptoms of brain disease". The Boston Medical ... In October 1872, a lecture by C.E. Brown-Sequard was published that proposed the then-revolutionary idea that one cerebral ...
This can be caused by brown sequard syndrome and hematomas in the fronto-parietal cortex near the middle that could produce a ... Brown Sequard Syndrome, mono neuritis multiplex. Treatments of Monoplegia typically includes physical therapy and counseling to ...
List of MeSH codes (C23)
... brown-sequard syndrome MeSH C23.888.592.636.711 --- pseudobulbar palsy MeSH C23.888.592.636.786 --- quadriplegia MeSH C23.888. ... postcholecystectomy syndrome MeSH C23.550.767.812 --- postgastrectomy syndromes MeSH C23.550.767.812.500 --- dumping syndrome ... adams-stokes syndrome MeSH C23.550.073.425.100 --- bundle-branch block MeSH C23.550.073.425.780 --- sinoatrial block MeSH ... short bowel syndrome MeSH C23.550.767.887 --- surgical wound dehiscence MeSH C23.550.767.925 --- surgical wound infection MeSH ...
Central cord syndrome
Spinal cord injury Anterior cord syndrome Posterior cord syndrome Brown-Sequard syndrome Rich V, McCaslin E (2006). "Central ... Central cord syndrome (CCS) is the most common form of cervical spinal cord injury. It is characterized by loss of motion and ... The syndrome is more common in people over the age of 50 because osteoarthritis in the neck region causes weakening of the ... This syndrome differs from that of a complete lesion, which is characterized by total loss of all sensation and movement below ...
List of MeSH codes (C10)
... brown-sequard syndrome MeSH C10.597.622.714 --- pseudobulbar palsy MeSH C10.597.622.760 --- quadriplegia MeSH C10.597.622.812 ... cri-du-chat syndrome MeSH C10.597.606.643.210 --- de lange syndrome MeSH C10.597.606.643.220 --- down syndrome MeSH C10.597. ... melas syndrome MeSH C10.228.140.163.100.540 --- menkes kinky hair syndrome MeSH C10.228.140.163.100.545 --- merrf syndrome MeSH ... rett syndrome MeSH C10.597.606.643.690 --- prader-willi syndrome MeSH C10.597.606.643.700 --- rubinstein-taybi syndrome MeSH ...
Brown-Séquard syndrome Hormone therapy C.-É. Brown-Séquard: De la transmission croisée des impressions sensitives par la moelle ... "Brown-Sequard, Charles Edouard (1817-1894) and Family". Retrieved 30 May 2009. The Practice of Neuroscience, pp. 199-200, John ... became the first to describe what is now called Brown-Séquard syndrome. Brown-Séquard was born at Port Louis, Mauritius, to an ... His name was immortalised in the history of medicine with the description of a syndrome which bears his name (Brown-Séquard ...
AIM25 text-only browsing: Royal College of Physicians: BROWN-SEQUARD, Charles Edouard (1817-1894) and Family. Aim25.ac.uk (1967 ... Da Costa's Syndrome 1942 Max Leonard Rosenheim, Baron Rosenheim of Camden, The Treatment of Urinary Infections (not given) 1943 ... Fever and Inflammation 1860 Charles Bland Radcliffe 1861 Charles Edouard Brown-Sequard 1862 Frederick William Pavy 1863 ... Pearce, J. M. S. (2003). "Derek Ernest Denny-Brown (1901-1981)". Journal of Neurology. 250 (7): 889-90. doi:10.1007/s00415-003- ...
Charles-Edouard Brown-Sequard, French physiologist and neurologist (1817-1894). Brown-Sequard studied medicine in Paris. He was professor of physiology and pathology at Harvard and subsequently taught in New York, London and Paris. He is best known for his work on the adrenal gland. In his experiments on hormonal secretions, he demon- strated the connection between excision of the adrenal glands and Addisons disease. He worked on the spinal cord and discovered the Brown- Sequard syndrome (crossed hemiplegia). He worked with various hormones, but his claim to have reversed his own ageing by injecting himself with dog testicular extracts is no longer accepted. - Stock Image H402/0163
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In a recent study, patients with Parkinson disease who engaged in body weight support treadmill training saw significant improvement in gait parameters and in clinical scales.
This page includes the following topics and synonyms: Spinal Cord Hemisection, Brown-Sequard Syndrome, Hemicord Syndrome, Hemiparaplegic Syndrome.
Buy Modalert Without Prescription - FDA Checked Pharmacy » Blog Archive » Acute Paraplegia Secondary to Hemorrhage of a...
Conclusion For most symptomatic spinal CM lesions, microsurgical resection is the treatment of choice when feasible. Microsurgical resection controls further bleeding and can prevent further neurological deterioration. Surgical resection is usually performed six weeks after hemorrhage to allow for resolution of cord edema, and for the development of a gliotic plane between the CM and surface of the cord via which resection may be performed. References 1. Brown-Sequard syndrome secondary to spontaneous bleed from postradiation cavernous angiomas. Mathews et al. AJNR 29:1989-1990 Nov 2008 2. De novo development of a lesion with the appearance of a cavernous malformation adjacent to an existing developmental venous anomaly. Campeau et al AJNR 26:156-159, Jan 2005 3. Management and prognosis of symptomatic patients with intramedullary spinal cord cavernoma. Liang et al. J Neurosurg Spine 15: 447-456, 2011 4. Practical Surgical Neuropathology: A Diagnostic Approach. Decker, Perry et al. 2010:527-550 ...
Hopeless at home in New Mexico, Dilon finds help at Shriners Hospitals for Children - Philadelphia | News and Events | Shriners...
In 2015, 2-year-old Dilon had a spinal cord stroke due to complications from surgery, causing paralysis from the waist down. "Life completed turned upside down," said Valarie, Dilons mother. Hospitals in Dilons native New Mexico had no experience with pediatric spinal cord injuries, according to his mother, who even searched for resources in Colorado and all over the U.S. "They just told me this is your new life, get used to it. I would ask questions and all they could say was we dont know. I had lost all hope until I saw a commercial for Shriners Hospitals for Children on television." Valarie called the number she saw in the advertisement on television which was a donation hotline. The operator was able to redirect her to a patient services line and they connected her to our Philadelphia Shriners Hospital. Since Dilons first visit with us in May 2016, his appointments include bouts of therapy that feature our TheraStride, a body-weight support treadmill system that helps the nervous ...
Finden Sie alle Bücher von Brown-Sequard, Edouard - Experimental Researches Applied to Physiology and Pathology (1853). Bei der Büchersuchmaschine eurobuch.com können Sie antiquarische und Neubücher VERGLEICHEN UND SOFORT zum Bestpreis bestellen. 1436896223
Looking for online definition of Brown-Sequard paralysis in the Medical Dictionary? Brown-Sequard paralysis explanation free. What is Brown-Sequard paralysis? Meaning of Brown-Sequard paralysis medical term. What does Brown-Sequard paralysis mean?
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press release Goetz, C. G. (2000). Battle of the titans - Charcot and Brown-Sequard on cerebral localization. Neurology, 54(9), 1840-1847. Objective: To examine the differing views of Jean-Martin Charcot and Charles Edouard Brown-Sequard-two celebrated neuroscientists of the nineteenth century-on cerebral localization as exemplified in their controversial debate of 1875 at the Societe de Biologie in Paris. Background: As clinicopathologic correlations were developed in the mid and late nineteenth century, cerebral localization was a primary topic of debate at scientific, social, and religious levels. Charcot, representing an anatomic approach to research, and Brown-Sequard, representing a physiologic perspective, disagreed fundamentally on the importance of cerebral localization to normal behavior and neurologic illness. Methods: The minutes of the Societe de Biologie meetings of 1875 and 1876, as well as primary archive documents from the Archives Nationales de 1Academie des Sciences and the ...
Professor Brown-Sequard recently read a most remarkable paper before the Biological Society of Paris. The aged professor believes he has discovered the secret of perpetual youth. The source is in young animals, guinea pigs, dogs, etc. - from which, while under the influence of anaesthetics, he abstracts organic matter, reduces it to a pulp in a mortar, dissolves all that is soluble in water, then subjects this solution to further chemical action, and finally injects it under the skin of the arm in doses of 1 c.c. at a time. The professor injected the matter into his own arm, and he reports that on the day after he had taken two injections, he felt completely transformed. He could work better, sleep better, and digest his food more perfectly. His appetite improved, and he gained 14 1bs. in weight. It true, these results may well be called extraordinary ...
Do you know why Sigmund Freud, esteemed psychoanalyst, had a vasectomy when he was 67 years old? How about William Butler Yeats, the famed writer, having his vasectomy at 69 years of age. Were they that sexually active and worried about conceiving? God bless them if this is true!. Hardly. Believe it or not, vasectomies were done in the roaring twenties and thirties in Austria by an endocrinologist named Steinach for physical and mental rejuvenation. "It revived my creative power," wrote Yeats in 1937. This may be true as Yeats wrote a crop of poems during this period that rank with his best work. At that time, a vasectomy was considered the "holy grail" of perpetual youth. Steinach felt that by blocking sperm flow, male hormone production in the testis would improve.. The idea of hormonal rejuvenation really started in earnest with an acclaimed endocrinologist named Brown-Sequard who in 1889 injected himself with testicular extracts from rats and dogs. This led to the trend of "organotherapy" in ...
Professor Brown-Sequard recently read a most remarkable paper before the Biological Society of Paris. The aged professor believes he has discovered the secret of perpetual youth. The source is in young animals, guinea pigs, dogs, etc. - from which, while under the influence of anaesthetics, he abstracts organic matter, reduces it to a pulp in a mortar, dissolves all that is soluble in water, then subjects this solution to further chemical action, and finally injects it under the skin of the arm in doses of 1 c.c. at a time. The professor injected the matter into his own arm, and he reports that on the day after he had taken two injections, he felt completely transformed. He could work better, sleep better, and digest his food more perfectly. His appetite improved, and he gained 14 1bs. in weight. It true, these results may well be called extraordinary ...
I wanna switch up my workout routine after using the same routine for about 3 months. I read somewhere that body-weight excersises (dips, chin ups
The spinal cord is surrounded by cerebrospinal fluid (spinal fluid) throughout its course in the spinal canal. The spinal fluid serves as a buffer of fluid that surrounds the spinal cord providing protection and insulation from movements and trauma to the body. The spinal fluid is kept in place by two thin membranes- the arachnoid and dura. The arachnoid is a very thin see through membrane that is suspended in the spinal fluid while the dura is a slightly thicker and stronger membrane that surrounds the spinal fluid space.. A ventral spinal cord herniation may occur if a breach or weakness of the dura occurs. Spinal fluid can leak through this opening causing headaches as part of a condition called spontaneous intracranial hypotension. In rare circumstances, the spinal cord may be pushed forward and protrude through the breach in the dura to produce a ventral spinal cord herniation. This condition usually occurs in the thoracic spine and can cause numbness and weakness in the legs with walking ...
May 4, 2016. Information on early-onset peripheral neuropathy, a disease VA. evidence to suggest that neuropathy of acute or subacute onset may be.. Clinical Professor, Department of Medical Oncology, Prince of Wales Hospital, Australia and Prince of Wales Clinical School, University of New South Wales.. Small Fiber Sensory Peripheral Neuropathy View FAQs and learn more from Cleveland Clinic about diagnosing small fiber sensory neuropathy with skin biopsies. Find additional resources and staff. Feb 27, 2015. In the last few years weve seen. Mar 19, 2014. Peripheral myelin protein 22 (PMP22)Charcot-Marie-Tooth disease type 1A. Neuropathy type III) is a hereditary neuropathy with early onset and severe presentation. Typically, CIDP shows a subacute or fluctuating course, multi- focal. Although not being a typical transient nerve palsy, sensorineural.. Disorders. All Disorders. NINDS Binswangers Disease Information Page; NINDS Brachial Plexus Injuries Information Page; NINDS Brown-Sequard ...
A 44-year-old woman was examined for progressive left lower extremity weakness and spasticity. Thoracic spine MR imaging and CT myelography showed a ventral dural defect at T7-T8 with an extradural subarachnoid fluid collection and extradural herniation of the spinal cord. Intraoperative sonography confirmed the appropriate level for dural entry and the finding of spinal cord herniation. After reduction of the herniated spinal cord, the patient experienced gradual improvement in neurologic function. ...
A workout using body weight can improve your bodys form and function with minimal equipment and a small time commitment. But the fact that you skipped the gym doesnt mean you can bend the rules for recovery. To avoid injury, make sure you give your body time to restore its equilibrium.
e.g. Fondaparinux- body-weight ,50 kg= 5 mg every 24 hours; body-weight 50-100 kg= 7.5 mg every 24 hours. NOT RECOMMENDED FOR CHILDREN ,17yrs ...
I like to devote at least one workout a week to strictly body-weight exercises. I posted the weight and time parameters that I use however you may want to do more or less based on your own fitness level. Note that any of the exercises can be done with or without weights. Complex 1 30 (s) …
Cervical Disc Herniation: Pain in the backside of the neck is referred to as posterior neck pain. There are many things that can cause neck pain - either acute or chronic.
Optimal treatment for Spinal Cord Injury associated with cervical canal Stenosis (OSCIS): A study protocol for a randomized...
TY - JOUR. T1 - Optimal treatment for Spinal Cord Injury associated with cervical canal Stenosis (OSCIS). T2 - A study protocol for a randomized controlled trial comparing early versus delayed surgery. AU - Chikuda, Hirotaka. AU - Ohtsu, Hiroshi. AU - Ogata, Toru. AU - Sugita, Shurei. AU - Sumitani, Masahiko. AU - Koyama, Yurie. AU - Matsumoto, Morio. AU - Toyama, Yoshiaki. PY - 2013/8/7. Y1 - 2013/8/7. N2 - Background: The optimal management of acute cervical spinal cord injury (SCI) associated with preexisting canal stenosis remains to be established. The objective of this study is to examine whether early surgical decompression (within 24 hours after admission) would result in greater improvement in motor function compared with delayed surgery (later than two weeks) in cervical SCI patients presenting with canal stenosis, but without bony injury.Methods/design: OSCIS is a randomized, controlled, parallel-group, assessor-blinded, multicenter trial. We will recruit 100 cervical SCI patients who ...
We have now now documented a tissue culture model method in which managed NC differentiation to SNPCs can be induced. Even further characterization of how the
SETS 3 TIME 2MIN TEMPO N/A REST 2MIN. Stand in front of a bench or box. Place one foot onto it, drive through the heel of your raised foot to step up with the other foot. Step back down with your lead-ing leg first. Switch legs ev-ery five reps.. ...
Radiographic and MRI characteristics of lumbar disseminated idiopathic spinal hyperostosis and spondylosis deformans in dogs -...
All dogs were found to be affected with both disseminated idiopathic spinal hyperostosis and spondylosis deformans. Neurological signs due to foraminal stenosis associated with disseminated idiopathic spinal hyperostosis were found in two dogs. Spondylosis deformans was associated with foraminal stenosis and/or disc protrusion in 15 cases.. The Pfirrmann score on magnetic resonance imaging was significantly higher in spondylosis deformans compared with disseminated idiopathic spinal hyperostosis and signal intensity of new bone due to disseminated idiopathic spinal hyperostosis was significantly higher compared to spondylosis deformans. ...
Manahawkin Chiropractic Center offers pain relieving Manahawkin chiropractic care for neck pain with radiculopathy from a cervical disc herniation.
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Few people with a thoracic disc herniation feel any symptoms or have any problems as a result of this condition. In rare cases when symptoms do arise, the main concern is whether the herniated disc is affecting the spinal cord.
Uterine cancer pathophysiology - ENDOMETRIAL - Definiția și sinonimele endometrial în dicționarul Engleză
The excision procedures - with electric loop LEEP, conization - increase the risk of complications, affecting the reproductive capacity: cervical canal stenosis, cervico-ischemic incompetence, premature birth, premature rupture of membranes 2.
Being on holiday is not that good for consistent training. Apart from the 7 hour car trip yesterday the bed I slept on last night is way too soft - this all translates into a pretty tight and uncomfortable body today. I decided to keep things relatively easy today and only did the BWER moderate day program with some joint mobility. Hopefully tomorrow I will grab the bells again. Today I did ...
Stand with your feet slightly beyond shoulder-width apart, toes forward, hands next to your sides (a). Simultaneously push your hips back and swing your arms backward, lowering your body until your thighs are almost parallel to the floor (b). Pause, then quickly push yourself back to the starting position, swinging your arms above your head and ending the movement on your toes (c).. MAKE IT EASIER: Put a box or chair behind you and squat to the surface each time (without resting your butt on the chair). Pause momentarily, then push yourself up.. MAKE IT HARDER: Jump up from the down position of the squat instead of just standing up.. ...
Rare Diseases (Some may not be rare in India) Acrocephalosyndactylia, Acrodermatitis, Addison Disease, Adie Syndrome, Alagille Syndrome, Amylose, Amyotrophic Lateral Sclerosis, Angelman Syndrome, Angiolymphoid Hyperplasia with Eosinophilia, Arnold-Chiari Malformation, Arthritis, Juvenile Rheumatoid, Asperger Syndrome, Bardet-Biedl Syndrome, Barrett Esophagus, Beckwith-Wiedemann Syndrome, Behcet Syndrome, Bloom Syndrome, Bowens Disease, Brachial Plexus Neuropathies, Brown-Sequard Syndrome, Budd-Chiari Syndrome, Burkitt Lymphoma, Carcinoma 256, Walker, Caroli Disease, Charcot-Marie-Tooth Disease, Chediak-Higashi Syndrome, Chiari-Frommel Syndrome, Chondrodysplasia Punctata, Colonic Pseudo-Obstruction, Colorectal Neoplasms, Hereditary Nonpolyposis, Craniofacial Dysostosis, Creutzfeldt-Jakob Syndrome, Crohn Disease, Cushing Syndrome, Cystic Fibrosis, Dandy-Walker Syndrome, De Lange Syndrome, Dementia, Vascular Dermatitis Herpetiformis, DiGeorge Syndrome, Diffuse Cerebral Sclerosis of Schilder, Duane ...
Looking for online definition of cervical canal in the Medical Dictionary? cervical canal explanation free. What is cervical canal? Meaning of cervical canal medical term. What does cervical canal mean?
Dear Readers, In 2012 it was found that I had a thoracic disc herniation at T7/T8. I was told that the herniation was severe and without surgery ASAP I would become paralyzed from the waist down. That is a scary thing to hear. But you know what else was scary? Finding out that this is…
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There is a common misperception in the fitness world that clients must have access to free weights, dumbbells and machines in order to experience significant strength-training results. Personal trainers recognize that body-weight training can be a powerful tool in any training arsenal. Suspension training is simply one more tool to add to that arsenal. This video will focus on creating an assortment of training programs that not only enhance overall strength, but have a profound effect on flexibility, balance, reaction and SAQ (speed, agility, quickness).
There is a common misperception in the fitness world that clients must have access to free weights, dumbbells and machines in order to experience significant strength-training results. Personal trainers recognize that body-weight training can be a powerful tool in any training arsenal. Suspension training is simply one more tool to add to that arsenal. This course will focus on creating an assortment of training programs that not only enhance overall strength, but have a profound effect on flexibility, balance, reaction and SAQ (speed, agility, quickness).
Brown-sequard Syndrome | Encyclopedia.com
... or partial spinal sensory syndrome, is a rare condition caused by an incomplete lesion of the spinal cord . ... Brown-Séquard syndrome Definition Brown-Séquard syndrome (BSS), also known as hemisection of the spinal cord  ... Brown-Séquard syndrome. Definition. Brown-Séquard syndrome (BSS), also known as hemisection of the spinal cord or partial ... Brown-Séquard syndrome (brown say-kar) n. the neurological condition resulting when the spinal cord has been damaged. Below the ...https://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/brown-sequard-syndrome
Create healthcare diagrams like this example called Brown-Sequard Syndrome in minutes with SmartDraw. SmartDraw includes 1000s ... Brown-Sequard Syndrome. Create healthcare diagrams like this example called Brown-Sequard Syndrome in minutes with SmartDraw. ... Brown-Sequard Syndrome. Posterior view of male figure with locations of symptomatology in Brown-Sequard syndrome indicated by ...https://www.smartdraw.com/neurology/examples/brownsequard-syndrome/
Case Study Part 2 - Patient with Brown-Sequard Syndrome | Odstock Medical Ltd (OML)
This article continues the story of a patient with Brown-Sequard Syndrome secondary to spinal stenosis. He uses a two-channel ... Case Study Part 2 - Patient with Brown-Sequard Syndrome. Tue 7th Jun, 2011 ... case_study_part_2_-_patient_with_brown-sequard_syndrome.pdf. 529.04 KB. ... You Are Here: Home \ Knowledge base \ APPLICATIONS \ Other gait related problems \ Case Study Part 2 - Patient with Brown- ...http://www.odstockmedical.com/knowledgebase/case-study-part-2-patient-brown-sequard-syndrome
Brown-sequard's syndrome: Definition with Brown-sequard's syndrome Pictures and Photos
Definition of Brown-sequards syndrome with photos and pictures, translations, sample usage, and additional links for more ... Brown-Sequards syndrome. Brown Bess. Brown Besses. Brown Betties. Brown Betty. Brown HT. Brown Swiss. Brown University. Brown ... Brown-sequards Syndrome Images Lexicographical Neighbors of Brown-sequards Syndrome. Broon. Broonale. Broonite. Brose. Brosme ... Brown. Brown-Adson forceps. Brown-Brenn stain. Brown-Sequards paralysis. ...http://lexic.us/definition-of/brown-sequard
Brown Sequard Syndrome Article - StatPearls
Brown Sequard Syndrome. Introduction. Famous Victorian scientist, Charles-Édouard Brown-Séquard, explained a rare spinal cord ... With Brown-Sequard syndrome, a clean-cut hemisection is usually not visible. However, partial hemisection is evident, and it ... Zeng Y,Ren H,Wan J,Lu J,Zhong F,Deng S, Cervical disc herniation causing Brown-Sequard syndrome: Case report and review of ... Wirz M,Zörner B,Rupp R,Dietz V, Outcome after incomplete spinal cord injury: central cord versus Brown-Sequard syndrome. Spinal ...https://statpearls.com/kb/viewarticle/18668/
Spontaneous thoracic extradural haematoma presenting as the Brown-Sequard syndrome  | [email protected]
Spontaneous thoracic extradural haematoma presenting as the Brown-Sequard syndrome . Authors: Seet, R.C.S. Wilder-Smith, E.P ... Spontaneous thoracic extradural haematoma presenting as the Brown-Sequard syndrome . Journal of Neurology 252 (6) : 731-733 ...http://scholarbank.nus.edu.sg/handle/10635/130497
Brown Sequard Syndrome - Causes, Symptoms, Diagnosis and Complications
Picture 2 - Brown Sequard Syndrome Image. Brown Sequard Syndrome is a paralyzing condition. Early treatment of the condition is ... www.patient.co.uk/doctor/Brown-Sequard-Syndrome.htm. http://www.apparelyzed.com/spinal-cord-injury/brown-sequard-syndrome.html ... Brown Sequard Syndrome Prognosis. Prognosis for this syndrome is commonly poor, although it is better than in the case of other ... Brown Sequard Syndrome Epidemiology. This syndrome is rare as a traumatic injury usually damages the nerve fibers around just ...https://www.primehealthchannel.com/brown-sequard-syndrome.html
New York Brown-Sequard Syndrome | NY Spinal Cord Injury Lawyer
New York Brown-Sequard Syndrome - NY Spinal Cord Injury Lawyer ... Common Causes of Brown-Sequard Syndrome. While Brown-Sequard ... New York Brown-Sequard Syndrome Lawyer. If you were injured in an accident that resulted in a Brown-Sequard syndrome injury or ... There are many different types of spinal cord injuries including Brown-Sequard syndrome. Brown-Sequard syndrome involves an ... the victim may end up with Brown-Sequard syndrome.. Other causes of Brown-Sequard are construction accidents and slip and fall ...https://spinalinjury.1800nynylaw.com/new-york-brown-sequard-syndrome.html
Brown-Sequard Syndrome (Brown Sequard Syndrome): Symptoms, Diagnosis and Treatment - Symptoma®
Brown-Sequard Syndrome (Brown Sequard Syndrome): Read more… ... Brown-Séquard syndrome (BSS) is a type of incomplete spinal ... Brown-Sequard Syndrome. Brown Sequard Syndrome. Brown-Séquard syndrome (BSS) is a type of incomplete spinal cord lesion with a ... Brown-Séquard syndrome (BSS) is also known as Brown-Séquards hemiplegia, Brown-Séquards paralysis, hemiparaplegic syndrome, ... Brown Sequard syndrome and a lesion of the left thoracic spinal cord were suspected initially.[ncbi.nlm.nih.gov] ...https://www.symptoma.com/en/info/brown-sequard-syndrome
Brown-Sequard syndrome | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program
... resources and questions answered by our Genetic and Rare Diseases Information Specialists for Brown-Sequard syndrome ... Brown-Sequard syndrome. is a rare neurological condition that results from an injury or damage to one side of the spinal cord. ... ClinicalTrials.gov lists trials that are related to Brown-Sequard syndrome. Click on the link to go to ClinicalTrials.gov to ... PubMed is a searchable database of medical literature and lists journal articles that discuss Brown-Sequard syndrome. Click on ...https://phgkb.cdc.gov/PHGKB/phgHome.action?action=forward&dbsource=cluster&id=26601
Welcome to the Acute SCI Forum - Page 5
Brown Sequard Syndrome Dear SCI Nurse,. Do you have any information about Brown Sequard Syndrome?? Prognosis? Forums? Success ...http://sci.rutgers.edu/forum/showthread.php?37268-Welcome-to-the-Acute-SCI-Forum&s=88a12181bdfb6946a9296cf63bcf2f3c&p=1298748
What Is Spinal Cord Injury / Disorder (SCI/D)
Brown-Sequard Syndrome. Brown-Sequard syndrome (BSS) is a rare neurological condition that creates a lesion in the spinal cord ... Brown-Sequard syndrome results in weakness or paralysis (hemiparaplegia) on one side of the body and a loss of sensation ( ... Brown-Sequard may be caused by a spinal cord tumor, trauma or puncture wound ot the back or neck, obstruction of a blood ... Cauda Equina Syndrome. Cauda equina syndrome is a serious debilitating condition caused by compression of the nerves in the ...http://www.unitedspinal.org/about/what-is-spinal-cord-injury-disorder-scid/
Functional Outcomes per Level of Spinal Cord Injury: Overview, Neurologic Level and Completeness of Injury, C1-C4 Tetraplegia ...
Brown-Sequard syndrome. Often attributed to spinal cord hemisection, Brown-Séquard syndrome is characterized by relative ... Posterior cord syndrome. The least common of the SCI clinical syndromes, posterior cord syndrome results from a selective ... Cauda equina syndrome. Because cauda equina syndrome is characterized by injury to the lumbosacral nerve root, it is not truly ... Anterior cord syndrome. Anterior cord syndrome, which is characterized by a variable loss of motor and pinprick sensation, has ...https://emedicine.medscape.com/article/322604-overview
Neurology Flashcards by 🌈 Languages | Brainscape
Brown-Sequard syndrome is characterised by loss of ipsilateral motor function and contralateral loss of pain and temperature ... Central cord syndrome usually occurs in patients over the age of 50 years as a result of extension injuries.. Upper limbs are ... Horners syndrome can also occur if the T1 nerve root is affected.. Lesions affecting the upper brachial plexus would lead to ... Compartment syndrome can occur in the absence of a fracture, for example, crush injuries.. Passive stretch of the muscles ...https://www.brainscape.com/flashcards/neurology-5315747/packs/7936498
Spinal Injury from Car Accident - Spinal Injury Lawyer
Brown-Sequard-Syndrome (BSS) is also referred to as partial spinal sensory syndrome, hemisection of the spinal cord, spastic ... Brown-Sequard Syndrome. If blood flow to either the left or the right side of the spinal cord gets affected, a victim is likely ... suffering Brown-Sequard Syndrome. Only one side of the body (left or right) experiences loss of movement, while the other side ... Anterior Cord Syndrome. This type of injury occurs when the blood flow to the front of the spinal cord gets interrupted. Also ...https://www.hoffmannpersonalinjury.com/spinal-injury-from-car-accident/
Comp Exam Flashcards by Molly Victorine | Brainscape
Brown-Sequard Syndrome UMN. hemisection of spinal cord. Ipsilateral loss of tactile discrimination, pressure, vibration and ...https://www.brainscape.com/flashcards/comp-exam-5995101/packs/7716964
Search Results - CareCure Forums
I am also C2-C5 Brown-Sequard syndrome. The... I am also C2-C5 Brown-Sequard syndrome. The burning feeling started about 1-2 ...http://sci.rutgers.edu/forum/search.php?searchid=6762968
Paralysis | Hemiplegia | MedlinePlus
Brown-Sequard Syndrome (National Institute of Neurological Disorders and Stroke) * Familial Periodic Paralyses (National ... Locked-In Syndrome (National Institute of Neurological Disorders and Stroke) * Todds Paralysis (National Institute of ...https://medlineplus.gov/paralysis.html
Spinal Cord Diseases | MedlinePlus
Brown-Sequard Syndrome (National Institute of Neurological Disorders and Stroke) * Central Pain Syndrome (National Institute of ... Stiff-Person Syndrome (National Institute of Neurological Disorders and Stroke) * Tabes Dorsalis (National Institute of ... Tethered Spinal Cord Syndrome (National Institute of Neurological Disorders and Stroke) * Transverse Myelitis (National ...https://medlineplus.gov/spinalcorddiseases.html
Neurology and Neurosurgery/Incomplete Spinal Cord Injuries/Brown-Séquard syndrome - Wikibooks, open books for an open world
It was concluded Brown Sequard Myelopathy patients can expect almost the same functional outcome as non-Brown Sequard ... Nine patients had true Brown-Séquard syndrome and nine others had pseudo-Brown-Séquard syndrome. Median duration of symptoms at ... Brown-Sequard syndrome is a rare yet classic type of spinal cord injury. Due to its rare occurrence most of the discriptions ... It illustrates that a Brown-Sequard syndrome can progress to a complete paraplegia, despite adequate treatment.    ...https://en.wikibooks.org/wiki/Neurology_and_Neurosurgery/Incomplete_Spinal_Cord_Injuries/Brown-S%C3%A9quard_syndrome
Walking Adaptability Post-Spinal Cord Injury - Full Text View - ClinicalTrials.gov
Brown-Sequard Syndrome. Spinal Cord Diseases. Central Nervous System Diseases. Nervous System Diseases. Trauma, Nervous System ... Incomplete Spinal Cord Injury Brown Sequard Syndrome Behavioral: Locomotor Training Other: Cross-Sectional Testing (No ...https://clinicaltrials.gov/show/NCT01851629
Syndrome Practice Test
Which of the following syndromes corresponds to: A failure of neutrophils to generate an immune response and lab values ... Which of the following syndromes corresponds to: maternal genetic phenotype syndrome?. *Brown-Sequard syndrome ... Which of the following syndromes corresponds to: C8/T1 nerve involvement and weakness in hand muscles?. *Brown-Sequard syndrome ... 8. Which of the following syndromes corresponds to: hematuria, glomerulonephritis and pulmonary dysfunction?. *Brown-Sequard ...https://www.testprepreview.com/modules/syndromes.htm
Neurology - Conditions treated - Mayo Clinic
Brown-Sequard syndrome. *Bulbar palsy (progressive). *Bulging disk. *CADASIL. *Carnitine deficiency. *Carnitine ...https://www.mayoclinic.org/departments-centers/neurology/sections/conditions-treated/orc-20117075?filterLetter=V
Walking Adaptability Post-Spinal Cord Injury - Full Text View - ClinicalTrials.gov
Brown-Sequard Syndrome. Spinal Cord Diseases. Central Nervous System Diseases. Nervous System Diseases. Trauma, Nervous System ... Incomplete Spinal Cord Injury Brown Sequard Syndrome Behavioral: Locomotor Training Other: Cross-Sectional Testing (No ...https://clinicaltrials.gov/ct2/show/NCT01851629?recr=Open&cond=%22Paraplegia%22&rank=18
Babinski's reflex and Clonus and Incomprehensible speech - Symptom Checker - check medical symptoms at RightDiagnosis
4. Battaglia Neri syndrome. 5. Brain cancer. 6. Brown-Sequard Syndrome. 7. Cerebral Palsy. 8. Chemical poisoning -- Helium. 9. ...http://wrongdiagnosis.com/cosymptoms/babinskis-reflex/clonus/incomprehensible-speech.htm
- Brown-S é quard syndrome (BSS), also known as hemisection of the spinal cord or partial spinal sensory syndrome, is a rare condition caused by an incomplete lesion of the spinal cord . (encyclopedia.com)
- Horner's syndrome: if the lesion is at or above T1, this will cause ipsilateral loss of sympathetic fibers resulting in ptosis, miosis, and anhydrosis. (statpearls.com)
- Careful examination of the wound site is necessary because it may reveal an injury to the dorsal column systems, spinothalamic tracts, dorsal and ventral spinocerebellar tracts, corticospinal tracts and Horner's syndrome (if the lesion is above or at the level of T1). (statpearls.com)
- Brown-Séquard syndrome (BSS) is a type of incomplete spinal cord lesion with a particular clinical pattern, which is characterized by the paralysis and loss of proprioception on the body side of the injury (ipsilateral) and loss of pain and temperature sensation on the opposite one. (symptoma.com)
- Brown Sequard syndrome and a lesion of the left thoracic spinal cord were suspected initially. (symptoma.com)
- Brown-Sequard syndrome (BSS) is a rare neurological disorder characterized by a lesion on the spinal cord which results in weakness or paralysis (hemiparaplegia) on one side of the body and a loss of sensation ( hemianesthesia ) on the opposite side. (symptoma.com)
- Brown-Séquard syndrome is an incomplete spinal cord lesion characterized by findings on clinical examination which reflect hemisection of the spinal cord (cutting the spinal cord in half on one or the other side). (wikipedia.org)
- Any presentation of spinal injury that is an incomplete lesion (hemisection) can be called a partial Brown-Séquard or incomplete Brown-Séquard syndrome. (wikipedia.org)
- This depends on the site of injury which can also involve the cervical or sympathetic thoracic trunk resulting in Horner's syndrome. (statpearls.com)
- Brown-Séquard Syndrome is a rare form of incomplete spinal cord injury which results after damage to one side of the spinal cord only (hemisection), typically in the neck (cervical spinal cord), or thoracic spinal cord, however, it could be anywhere along the length of the spinal cord. (statpearls.com)
- Brown-Sequard syndrome most commonly occurs in the the thoracic spine (upper and middle back). (cdc.gov)
- Brown-Séquard syndrome may be caused by a spinal cord tumour, trauma [such as a gunshot wound or puncture wound to the cervical (neck) or thoracic spine (back)], ischemia (obstruction of a blood vessel), or infectious or inflammatory diseases such as tuberculosis, or multiple sclerosis. (wikipedia.org)
- Brown Se'quard syndrome is an incomplete pattern of injury showing a hemisection of the spinal cord which results in weakness and paralysis on one side of the damage and loss of pain and temperature sensations on the opposite side. (statpearls.com)
- With Brown-Sequard syndrome, a clean-cut hemisection is usually not visible. (statpearls.com)
- Hemisection syndrome, having additional signs and symptoms, can also be seen. (primehealthchannel.com)
- Brown-Sequard-Syndrome (BSS) is also referred to as partial spinal sensory syndrome, hemisection of the spinal cord, spastic spinal monoplegia syndrome, and hemiparaplegic syndrome. (hoffmannpersonalinjury.com)
- Posterior view of male figure with locations of symptomatology in Brown-Sequard syndrome indicated by different colors. (smartdraw.com)
- A relatively rare syndrome that is caused by compression of the posterior spinal artery and is characterized by loss of pain perception, proprioception, two-point discrimination, and stereognosis. (studystack.com)
- Brown-Séquard syndrome (also known as Brown-Séquard's hemiplegia, Brown-Séquard's paralysis, hemiparaplegic syndrome, hemiplegia et hemiparaplegia spinalis, or spinal hemiparaplegia) is caused by damage to one half of the spinal cord, resulting in paralysis and loss of proprioception on the same (or ipsilateral) side as the injury or lesion, and loss of pain and temperature sensation on the opposite (or contralateral) side as the lesion. (wikipedia.org)
- Brown-Sequard syndrome is characterised by loss of ipsilateral motor function and contralateral loss of pain and temperature sensation. (brainscape.com)
- 9. Which of the following syndromes corresponds to: presence of ipsilateral motor loss and contralateral spinothalmic tract damage? (testprepreview.com)
- Brown-Séquard syndrome is characterized by loss of motor function (i.e. hemiparaplegia), loss of vibration sense and fine touch, loss of proprioception (position sense), loss of two-point discrimination, and signs of weakness on the ipsilateral (same side) of the spinal injury. (wikipedia.org)
- We report the first case of a chronic cervical stenosis presenting with an acute Brown-Séquard syndrome after a severe coughing episode. (symptoma.com)
- In a related case, the authors described the history of a patient who was stabbed in the back of his neck with a knife and who later presented with a Brown-Séquard syndrome attributable to cervical spinal cord damage. (wikibooks.org)
- While Brown-Sequard syndrome can be caused by a tumor on the spine of diseases such as tuberculosis or multiple sclerosis, it is also commonly caused by spinal cord trauma that occurs in accidents. (1800nynylaw.com)
- Other conditions and syndromes which show similar clinical signs to those of BSS include spinal cord compression, stroke, multiple sclerosis, and spinal tumors . (symptoma.com)
- There are several causes of Brown-Sequard syndrome, including: a spinal cord tumor , trauma (such as a puncture wound to the neck or back), infectious or inflammatory diseases ( tuberculosis or multiple sclerosis ), and disk herniation . (cdc.gov)
- Depending on what part of the spine is damaged, the victim may end up with Brown-Sequard syndrome. (1800nynylaw.com)
- Anterior cord syndrome is not completely curable, but with the right treatment, the victim can experience some improvement. (hoffmannpersonalinjury.com)
- If blood flow to either the left or the right side of the spinal cord gets affected, a victim is likely suffering Brown-Sequard Syndrome. (hoffmannpersonalinjury.com)
- This syndrome is rare as a traumatic injury usually damages the nerve fibers around just one end of the spinal cord. (primehealthchannel.com)
- Brown-Sequard syndrome is a rare neurological condition that results from an injury or damage to one side of the spinal cord . (cdc.gov)
- Brown-Sequard syndrome is a rare yet classic type of spinal cord injury. (wikibooks.org)
- There are many different types of spinal cord injuries including Brown-Sequard syndrome. (1800nynylaw.com)
- Like many other types of spinal cord injuries, Brown-Sequard syndrome is an injury that is often suffered as a result of negligence. (1800nynylaw.com)
- If you sustained a Brown-Sequard syndrome injury due to the negligence or intentional act of another person, contact an experienced New York Brown-Sequard Syndrome Lawyer who will review the facts of your case and explain to you the process for filing a personal injury lawsuit in order to demand compensation from those responsible for your injuries. (1800nynylaw.com)
- Victims who suffer from spinal cord injuries including Brown-Sequard, typically have significant medical bills. (1800nynylaw.com)
- If you were injured in an accident that resulted in a Brown-Sequard syndrome injury or another serious spinal cord injury, contact an experienced attorney who understands both the legal issues associated with personal injury cases as well as the medical issues associated with injuries to the spine. (1800nynylaw.com)
- Information on the prevalence of Brown-S é quard syndrome is collected from 16 spinal cord injury centers in the United States . (encyclopedia.com)
- If the syndrome develops due to some knife injury or a gunshot, other serious conditions such as organ damage or bleeding may crop up. (primehealthchannel.com)
- Brown-Sequard syndrome involves an injury to one side of the spinal cord. (1800nynylaw.com)
- If you are now suffering from Brown-Sequard syndrome follow an accidental or intentional act of another person, under New York law you have the right to pursue compensation through a personal injury claim. (1800nynylaw.com)