Bronchopulmonary Dysplasia
A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
Aspergillosis, Allergic Bronchopulmonary
Infant, Very Low Birth Weight
Respiratory Distress Syndrome, Newborn
A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause.
Infant, Extremely Low Birth Weight
Gestational Age
Bronchopulmonary Sequestration
A developmental anomaly in which a mass of nonfunctioning lung tissue lacks normal connection with the tracheobroncheal tree and receives an anomalous blood supply originating from the descending thoracic or abdominal aorta. The mass may be extralobar, i.e., completely separated from normally connected lung, or intralobar, i.e., partly surrounded by normal lung.
Lung
Respiration, Artificial
Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have RESPIRATORY INSUFFICIENCY to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2).
Intensive Care Units, Neonatal
Oxygen Inhalation Therapy
Fibrous Dysplasia of Bone
Ureaplasma urealyticum
Chorioamnionitis
Pulmonary Surfactants
Respiratory Aspiration
Pulmonary Alveoli
Intensive Care, Neonatal
Ectodermal Dysplasia
A group of hereditary disorders involving tissues and structures derived from the embryonic ectoderm. They are characterized by the presence of abnormalities at birth and involvement of both the epidermis and skin appendages. They are generally nonprogressive and diffuse. Various forms exist, including anhidrotic and hidrotic dysplasias, FOCAL DERMAL HYPOPLASIA, and aplasia cutis congenita.
Papio
A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of five named species: PAPIO URSINUS (chacma baboon), PAPIO CYNOCEPHALUS (yellow baboon), PAPIO PAPIO (western baboon), PAPIO ANUBIS (or olive baboon), and PAPIO HAMADRYAS (hamadryas baboon). Members of the Papio genus inhabit open woodland, savannahs, grassland, and rocky hill country. Some authors consider MANDRILLUS a subgenus of Papio.
Lung Injury
Ureaplasma
Leukomalacia, Periventricular
Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)
Infant, Low Birth Weight
Developmental Disabilities
Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)
Ambroxol
Trachea
Retinopathy of Prematurity
A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)
Aspergillus fumigatus
Sucking Behavior
Consensus Development Conferences, NIH as Topic
Articles on conferences sponsored by NIH presenting summary statements representing the majority agreement of physicians, scientists, and other professionals convening for the purpose of reaching a consensus on a subject of interest. This heading is used for NIH consensus conferences as a means of scientific communication. In indexing it is viewed as a type of review article and as a tag for any article appearing in any publication of the NIH Office of Medical Applications of Research (OMAR).
Ductus Arteriosus, Patent
Apgar Score
A method, developed by Dr. Virginia Apgar, to evaluate a newborn's adjustment to extrauterine life. Five items - heart rate, respiratory effort, muscle tone, reflex irritability, and color - are evaluated 60 seconds after birth and again five minutes later on a scale from 0-2, 0 being the lowest, 2 being normal. The five numbers are added for the Apgar score. A score of 0-3 represents severe distress, 4-7 indicates moderate distress, and a score of 7-10 predicts an absence of difficulty in adjusting to extrauterine life.
Premature Birth
Hyaline Membrane Disease
A respiratory distress syndrome in newborn infants, usually premature infants with insufficient PULMONARY SURFACTANTS. The disease is characterized by the formation of a HYALINE-like membrane lining the terminal respiratory airspaces (PULMONARY ALVEOLI) and subsequent collapse of the lung (PULMONARY ATELECTASIS).
Birth Weight
Maximal Expiratory Flow Rate
Pregnancy
Functional Residual Capacity
Uterine Cervical Dysplasia
Fibromuscular Dysplasia
An idiopathic, segmental, nonatheromatous disease of the musculature of arterial walls, leading to STENOSIS of small and medium-sized arteries. There is true proliferation of SMOOTH MUSCLE CELLS and fibrous tissue. Fibromuscular dysplasia lesions are smooth stenosis and occur most often in the renal and carotid arteries. They may also occur in other peripheral arteries of the extremity.
Intermittent Positive-Pressure Ventilation
Continuous Positive Airway Pressure
A technique of respiratory therapy, in either spontaneously breathing or mechanically ventilated patients, in which airway pressure is maintained above atmospheric pressure throughout the respiratory cycle by pressurization of the ventilatory circuit. (On-Line Medical Dictionary [Internet]. Newcastle upon Tyne(UK): The University Dept. of Medical Oncology: The CancerWEB Project; c1997-2003 [cited 2003 Apr 17]. Available from: http://cancerweb.ncl.ac.uk/omd/)
Suction
Psychomotor Disorders
Administration, Inhalation
Bronchoalveolar Lavage Fluid
Ventilator Weaning
Techniques for effecting the transition of the respiratory-failure patient from mechanical ventilation to spontaneous ventilation, while meeting the criteria that tidal volume be above a given threshold (greater than 5 ml/kg), respiratory frequency be below a given count (less than 30 breaths/min), and oxygen partial pressure be above a given threshold (PaO2 greater than 50mm Hg). Weaning studies focus on finding methods to monitor and predict the outcome of mechanical ventilator weaning as well as finding ventilatory support techniques which will facilitate successful weaning. Present methods include intermittent mandatory ventilation, intermittent positive pressure ventilation, and mandatory minute volume ventilation.
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Disease Models, Animal
Fatty Alcohols
Usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4 carbons, derived from natural fats and oils, including lauryl, stearyl, oleyl, and linoleyl alcohols. They are used in pharmaceuticals, cosmetics, detergents, plastics, and lube oils and in textile manufacture. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Respiratory Function Tests
Fibrous Dysplasia, Polyostotic
Fetus
Lung Diseases, Fungal
Oxygen
Enterocolitis, Necrotizing
Prospective Studies
Hip Dysplasia, Canine
Cleidocranial Dysplasia
Retinal Dysplasia
Infant, Newborn, Diseases
Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.
Cerebral Palsy
A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
Risk Factors
Follow-Up Studies
Hip Dislocation, Congenital
Early inhaled glucocorticoid therapy to prevent bronchopulmonary dysplasia. (1/452)
BACKGROUND: The safety and efficacy of inhaled glucocorticoid therapy for asthma stimulated its use in infants to prevent bronchopulmonary dysplasia. We tested the hypothesis that early therapy with inhaled glucocorticoids would decrease the frequency of bronchopulmonary dysplasia in premature infants. METHODS: We conducted a randomized, multicenter trial of inhaled beclomethasone or placebo in 253 infants, 3 to 14 days old, born before 33 weeks of gestation and weighing 1250 g or less at birth, who required ventilation therapy. Beclomethasone was delivered in a decreasing dosage, from 40 to 5 microg per kilogram of body weight per day, for four weeks. The primary outcome measure was bronchopulmonary dysplasia at 28 days of age. Secondary outcomes included bronchopulmonary dysplasia at 36 weeks of postmenstrual age, the need for systemic glucocorticoid therapy, the need for bronchodilator therapy, the duration of respiratory support, and death. RESULTS: One hundred twenty-three infants received beclomethasone, and 130 received placebo. The frequency of bronchopulmonary dysplasia was similar in the two groups: 43 percent in the beclomethasone group and 45 percent in the placebo group at 28 days of age, and 18 percent in the beclomethasone group and 20 percent in the placebo group at 36 weeks of postmenstrual age. At 28 days of age, fewer infants in the beclomethasone group than in the placebo group were receiving systemic glucocorticoid therapy (relative risk, 0.6; 95 percent confidence interval, 0.4 to 1.0) and mechanical ventilation (relative risk, 0.8; 95 percent confidence interval, 0.6 to 1.0). CONCLUSIONS: Early beclomethasone therapy did not prevent bronchopulmonary dysplasia but was associated with lower rates of use of systemic glucocorticoid therapy and mechanical ventilation. (+info)Effect of early ambroxol treatment on lung functions in mechanically ventilated preterm newborns who subsequently developed a bronchopulmonary dysplasia (BPD). (2/452)
In a randomized trial in 102 preterm newborns with respiratory distress syndrome (RDS) it has been shown that early Ambroxol treatment (30 mg kg(-1) over the first 5 days) significantly reduces the incidence of RDS-associated complications [bronchopulmonary dysplasia (BPD), intraventricular haemorrhage, post-natal acquired pneumonia]. The aim of the present analysis was to investigate the effect of Ambroxol treatment on lung function in newborns who developed BPD. Respiratory function testing (RFT) was performed immediately after extubation and at day 28. Tidal volume (VT) and respiratory frequency (f) were measured during tidal breathing using the deadspace free flow-through technique. The lung mechanic parameter VT/maxPes was determined by measuring the maximal oesophageal pressure changes, maxPes, with a catheter tip pressure transducer. In the placebo group 36/50 infants were extubated within the first 28 days of life and 13/36 (36%) developed BPD. In the Ambroxol group 44/52 were extubated and 9/44 (20%) developed BPD. After extubation, RFT showed (i) no statistically significant difference in the ventilatory parameters of either treatment group, (ii) improved (P<0.05) lung mechanics (VT/maxPes) in Ambroxol group compared to controls (94+/-27 ml kPa(-1) vs. 8.1+/-2.6 ml kPa(-1)) and (iii) no statistically significant difference in lung function between infants with and without BPD. At day 28 we found (i) no effect of early Ambroxol treatment on lung functions, (ii) significantly (P < 0.05) higher f (58.5+/-11.7 min(-1) vs. 49.7+/-10.1 min(-1)) and significantly (P<0.01) lower V(T) (9.6+/-1.9 ml vs. 12.3+/-2.7 ml) and V(T)/maxPes (8.9+/-2.6 ml kPa(-1)] vs. 12.0+/-2.9 ml kPa(-1)) in infants with BPD compared to infants without and (iii) these differences are not influenced by early Ambroxol treatment. If the process of BPD development is induced, early Ambroxol treatment has no influence on impaired lung function at day 28. (+info)Use of corticosteroids and the outcome of infants with bronchopulmonary dysplasia. (3/452)
Ventilator-dependent premature infants are often treated with dexamethasone. Several trials showed that steroids while improve pulmonary compliance and facilitate extubation, some treated infants may have adverse effects, such as alterations of growth curves. We conducted this retrospective study to evaluate the effects of steroids on mechanical ventilation, oxygen therapy, hospital length stay and mortality, in ventilator-dependent infants with bronchopulmonary dysplasia (BPD) (defined as the need of oxygen supplementation at 28 days of life). Twenty-six newborns with BPD were evaluated during 9 - 42 days postpartum (mean = 31 days) and were divided into two groups: Group I - 14 newborns that did not receive dexamethasone, and Group II - 12 newborns that received dexamethasone at 14 - 21 days of life. Dexamethasone was given at a dose of 0.25 mg per kilogram of body weight twice daily intravenously for 3 days, after which the dose was tapered. RESULTS: There were no statistically significant differences in the mean length of mechanical ventilation (Group I - 37 days, Group II - 35 days); oxygen supplementation (Group I - 16 days, Group II - 29 days); hospital stay (Group I - 72 days, Group II - 113 days); mortality (Group I - 35.7%, Group II - 41.6%). At birth, Group II was lighter (BW: Group I - 1154 grams +/- 302, Group II - 791 grams +/- 165; p < 0.05) and smaller (height: Group I - 37.22 cm +/- 3.3, Group II - 33.5 +/- 2.4; p< 0.05) than Group I. At 40 weeks, there were no statistically significant differences between groups in relation to anthropometric measurements. CONCLUSIONS: The use of corticosteroids in bronchopulmonary dysplasic infants may influence the somatic growth during its use. However, after its suspension, a recovery seems to occur, suggesting that its influence could be transitory. (+info)Cytokine response during hyperoxia: sequential production of pulmonary tumor necrosis factor and interleukin-6 in neonatal rats. (4/452)
BACKGROUND: Exposure of newborn animals to high concentrations of oxygen leads to diffuse alveolar damage similar to that seen in bronchopulmonary dysplasia in human infants. Therefore, neonatal rats are a suitable practical model of hyperoxic lung damage in human infants. OBJECTIVE: To determine the involvement of tumor necrosis factor-alpha and interleukin-6 in lung injury in neonatal rats exposed to 100% O2 concentration. METHODS: A randomized controlled study was designed in which litters of term Sprague-Dawley rat pups were assigned to experimental or control groups. The pups in the experimental group were placed in 100% O2 from birth for 9 days, while the control pups were placed in room air. Twelve to 15 pups from each group were sacrificed on day 1, 3, 6, 9 and 13 after birth for bronchoalveolar lavage collection and lung histologic study. The bronchoalveolar lavage fluid was assayed for TNF alpha and IL-6. RESULTS: Newborn rats exposed to 100% O2 for the first 9 days of life showed severe pulmonary edema and hypercellularity on days 1 and 3, which then improved to nearly complete resolution on days 6 and 9. Pulmonary TNF alpha was produced early on O2 exposure (day 3) and pulmonary IL-6 later (days 6 and 9). CONCLUSIONS: Hyperoxia induces sequential production of pulmonary TNF alpha and IL-6, which corresponds to the severity of the pathological findings and the known inflammatory and anti-inflammatory role of these cytokines. (+info)Birth weight <1501 g and respiratory health at age 14. (5/452)
AIMS: To determine the respiratory health in adolescence of children of birth weight <1501 g, and to compare the results with normal birthweight controls. METHODS: Prospective cohort study of children born in the Royal Women's Hospital, Melbourne. Two cohorts of preterm children (86 consecutive survivors 500-999 g birth weight, and 124 consecutive survivors 1000-1500 g birth weight) and a control group of 60 randomly selected children >2499 g birth weight were studied. Children were assessed at 14 years of age. A paediatrician determined the clinical respiratory status. Lung function was measured according to standard guidelines. RESULTS: Of 180 preterm children seen at age 14, 42 (23%) had bronchopulmonary dysplasia (BPD) in the newborn period. Readmission to hospital for respiratory ill health was infrequent in all groups and the rates of asthma were similar (15% in the 500-999 g birth weight group, 21% in the 1000-1500 g birth weight group, 21% in controls; 19% BPD, 18% no BPD). Overall, lung function was mostly within the normal range for all cohorts; few children had lung function abnormalities in clinically significant ranges. However, the preterm children had significantly lower values for variables reflecting flow. Lung function in children of 500-999 g birth weight was similar to children of 1000-1500 g birth weight. Preterm children with BPD had significantly lower values for variables reflecting flow than children without BPD. CONCLUSIONS: The respiratory health of children of birth weight <1501 g at 14 years of age is comparable to that of term controls. (+info)Chronic pulmonary insufficiency in children and its effects on growth and development. (6/452)
Conditions leading to chronic pulmonary insufficiency can affect infants and children. These can lead to growth failure and delayed development. Among the most common and severe of these are bronchopulmonary dysplasia (BPD) and cystic fibrosis. In addition to the respiratory consequences of these diseases, there is ample evidence that they lead to decreased growth as a result of decreased energy intake and increased energy expenditure. Furthermore, there is evidence that infants with BPD may also have delayed development, independent of the effects of their prematurity. Enhancing the long-term outlook for these conditions may therefore require consideration of both improved pulmonary management and aggressive nutritional management to limit growth failure and potentially enhance developmental outcome. Specific micronutrient supplementation, such as antioxidant therapy, may also enhance pulmonary and nutritional status. (+info)Special nutritional needs of infants for prevention of and recovery from bronchopulmonary dysplasia. (7/452)
Extremely low birth weight infants who develop severe respiratory disease may have special nutrient requirements imposed by a combination of enhanced utilization of nutrients or the need for epithelial cell repair resulting from the disease process, as well as to support catch-up growth. Inositol, free fatty acids, vitamin E and vitamin A are proposed as nutrients for which infants at risk of chronic pulmonary insufficiency may have special requirements. Of these nutrients, only for vitamin A does suggestive evidence exist that high doses when given intramuscularly may reduce the incidence of death or chronic lung disease. Exogenous steroid therapy (dexamethasone), which is often used to improve pulmonary compliance in ventilated premature infants, may compromise vitamin A status and induce restricted somatic and bone mineral growth. Supplemental nutrition by means of enriched infant formulas has provided benefits in growth and bone mass accretion to infants recovering from bronchopulmonary dysplasia up to 3-mo corrected age. This growth advantage was not sustained over the subsequent 9 mo, suggesting that prolonged nutritional support is required until catch-up growth is complete. Further studies are required to delineate the needs for specific nutrients such as antioxidant vitamins and minerals or vitamin A that may play a role in preventing severe chronic lung disease in premature infants. As well, the role of supplemental nutrition (beyond the requirements of term infants) to support catch-up growth and maintenance during the critical stages of early development requires further investigation before evidence-based nutrient recommendations can be developed for this special population of infants. (+info)Is there a role for antioxidant therapy in bronchopulmonary dysplasia? (8/452)
Bronchopulmonary dysplasia (BPD) is a chronic lung disease first described in 1967 as a complication of therapy for premature infants with hyaline membrane disease, and treatment with high concentrations of oxygen was thought to be a major contributor to its development. Thus, interventions to enhance lung antioxidants to prevent the development of BPD were considered appropriate therapeutic strategies. In the last decades, advances in the acute care of premature infants has reduced the reliance on therapy with high concentrations of supplemental oxygen. However, the incidence of BPD has not changed significantly. The changing clinical context in which BPD develops begs the question of whether oxidation is important in the development of BPD and, therefore, whether designing interventions enhancing lung antioxidants is still warranted. This review presents evidence that premature infants that will develop BPD have qualitative and quantitative differences in oxidation of lipids and proteins when compared to infants that do not develop BPD. Such differences in oxidation patterns are the most obvious in the first few days of life. The emerging evidence thus supports the concept that the lung injury process leading to the development of BPD occurs within hours to days of delivery and that oxidation is a major contributor to this pathological process. Unfortunately, early attempts at delivery of antioxidants to the lung have not been successful, perhaps because of an inability to deliver antioxidants in a timely manner to the areas in the lung in which deleterious oxidations are occurring. Further research is necessary to determine both the nature and the location of the oxidative events that lead to the development of early lung injury, so that more appropriate and specific antioxidant interventions can be designed. (+info)
Erratum: Serial Changes of Serum Endostatin and Angiopoietin-1 Levels in Preterm Infants with Severe Bronchopulmonary Dysplasia...
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Home oxygen promotes weight gain in infants with bronchopulmonary dysplasia
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Bronchopulmonary dysplasia
... "Bronchopulmonary Dysplasia". American Lung Association. Retrieved 2020-03-12. Northway Jr, WH; ... "Bronchopulmonary Dysplasia". Patient.info. Retrieved 2 February 2014. Jobe, AH; Bancalari, E (June 2001). "Bronchopulmonary ... Bronchopulmonary dysplasia (BPD; part of the spectrum of chronic lung disease of infancy) is a chronic lung disease in which ... Infants with bronchopulmonary dysplasia are often treated with diuretics that decrease fluid in the alveoli where gas exchange ...
Oxygen toxicity
Bronchopulmonary dysplasia is reversible in the early stages by use of break periods on lower pressures of oxygen, but it may ... Bronchopulmonary dysplasia is among the most common complications of prematurely born infants and its incidence has grown as ... Bronchopulmonary dysplasia was first described by Northway in 1967, who outlined the conditions that would lead to the ... Diagnosis of bronchopulmonary dysplasia in newborn infants with breathing difficulties is difficult in the first few weeks. ...
Infant respiratory distress syndrome
Bronchopulmonary dysplasia". The New England Journal of Medicine. 276 (7): 357-68. doi:10.1056/NEJM196702162760701. PMID ... Chronic lung disease, including bronchopulmonary dysplasia, is common in severe RDS. The etiology of BPD is problematic and may ... Bubble CPAP Bronchopulmonary dysplasia Pulmonary hypoplasia Surfactant metabolism dysfunction Surfactant therapy Wilson-Mikity ... to successfully decrease the use of mechanical ventilation and lower the incidence of bronchopulmonary dysplasia (BPD). Since ...
Respiratory disease
Bronchopulmonary Dysplasia is a condition that occurs after birth usually from mechanical ventilation and oxygen use. It ... "Bronchopulmonary Dysplasia". www.lung.org. Retrieved 2022-05-07. "Meconium aspiration syndrome: MedlinePlus Medical ...
Pulmonary hygiene
Goodman G (2007). "Chronic pulmonary disease: Bronchopulmonary dysplasia". In Perkin RM, Swift JD, Dale AN, Anas NG (eds.). ...
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PAMR1 has been associated with bronchopulmonary dysplasia. It is thought to play an important role in respiratory physiology. ...
Christian P. Speer
Inflammatory Mechanisms in Bronchopulmonary Dysplasia. In: Bronchopulmonary Dysplasia, Abman SH (Ed.) Informa Healthcare, New ... the bronchopulmonary dysplasia (BPD). These findings have opened the way for various anti-inflammatory therapeutic strategies. ... of pulmonary inflammation and increased microvascular permeability during the development of bronchopulmonary dysplasia: a ...
Prohibition of drugs
Caffeine is used to treat bronchopulmonary dysplasia. In most cultures, caffeine in the form of coffee or tea is unregulated. ...
Low birth weight
Kalikkot Thekkeveedu, Renjithkumar; Guaman, Milenka Cuevas; Shivanna, Binoy (November 2017). "Bronchopulmonary dysplasia: A ... while comorbidities such as bronchopulmonary dysplasia may increase them. Daily weight gain can reveal whether a VLBW newborn ...
Václav Vojta
"Improved lung function by Vojta-therapy in bronchopulmonary dysplasia". ResearchGate. "Recipients of Medal of Merit" (PDF). ... Vojta Therapy has been used to treat cerebral palsy, peripheral paralysis of the arms and legs, hip dysplasia, and problems in ...
Caffeine
... is used in: Bronchopulmonary dysplasia in premature infants for both prevention and treatment. It may improve weight ... It can treat and prevent the premature infant breathing disorders bronchopulmonary dysplasia of prematurity and apnea of ... Kugelman A, Durand M (December 2011). "A comprehensive approach to the prevention of bronchopulmonary dysplasia". Pediatric ...
Pulmonary interstitial emphysema
Bronchopulmonary dysplasia Chalak LF, Kaiser JR, Arrington RW (2007). "Resolution of pulmonary interstitial emphysema following ... of PIE the length of time of mechanical ventilation needed may increase and the incidence of bronchopulmonary dysplasia becomes ...
Wilson-Mikity syndrome
It is closely related to bronchopulmonary dysplasia (BPD), differing mainly in the lack of prior ventilatory support. All the ... Hodgman JE (Dec 2003). "Relationship between Wilson-Mikity syndrome and the new bronchopulmonary dysplasia". Pediatrics. 112 (6 ... Infant respiratory distress syndrome Bronchopulmonary dysplasia Chronic obstructive pulmonary disease Retrolental Fibroplasia ...
Analeptic
Bronchopulmonary dysplasia is common in infants with low birth weight (. ... Ample research also suggests that caffeine significantly reduces the occurrence of bronchopulmonary dysplasia, which is a ... and bronchopulmonary dysplasia in newborn infants. Caffeine is a weak bronchodilator, which explains the relief of the effects ...
Endothelial colony forming cell
A low number of ECFCs has been identified as a risk factor for infant diseases such as bronchopulmonary dysplasia. ECFCs can ... "Cord blood angiogenic progenitor cells are decreased in bronchopulmonary dysplasia". Eur. Respir. J. 40 (6): 1516-22. doi: ...
Lysozyme
Reduced lysozyme levels have been associated with bronchopulmonary dysplasia in newborns. Piglets fed with human lysozyme milk ... association with the development of bronchopulmonary dysplasia". The Journal of Pediatrics. 121 (2): 262-270. doi:10.1016/S0022 ...
Yoon Bo-hyun
... cerebral palsy and bronchopulmonary dysplasia, seem to be initiated before birth in some, and can be prevented and treated from ... and the risk for the development of bronchopulmonary dysplasia". American Journal of Obstetrics and Gynecology. 177 (4): 825-30 ... "A systemic fetal inflammatory response and the development of bronchopulmonary dysplasia". American Journal of Obstetrics and ... that intrauterine infection/inflammation is an important risk factor for the development of bronchopulmonary dysplasia which is ...
Continuous positive airway pressure
It is associated with a decrease in the incidence of bronchopulmonary dysplasia. In some preterm infants whose lungs have not ...
Preterm birth
Babies born before 32 weeks probably have a lower risk of death from bronchopulmonary dysplasia if they have CPAP immediately ... previously called bronchopulmonary dysplasia or BPD). Gastrointestinal and metabolic issues can arise from neonatal ...
Exhaled nitric oxide
Low levels have been found in primary ciliary dyskinesia, bronchopulmonary dysplasia, and pulmonary arterial hypertension. In ...
Bubble CPAP
It is also associated with a decreased incidence of bronchopulmonary dysplasia (BPD) compared to mechanical ventilation. Not ...
Ureaplasma urealyticum
Some patients have given birth to children subjected to bronchopulmonary dysplasia, Intraventricular hemorrhage, and ...
Mycoplasma
... species are associated with infant respiratory distress syndrome, bronchopulmonary dysplasia, and intraventricular ...
Palivizumab
... children less than two years of age and requiring treatment for bronchopulmonary dysplasia within the last six months; children ...
Rowan Crothers
Crothers' prematurity resulted in him developing cerebral palsy due to IVH, and bronchopulmonary dysplasia causing permanent ...
Chorioamnionitis
Long-term infant complications like bronchopulmonary dysplasia, cerebral palsy, and Wilson-Mikity syndrome have been associated ...
Lucinactant
05-23-2006 Prevention of bronchopulmonary dysplasia in premature infants 10-21-2005 Treatment of bronchopulmonary dysplasia in ... October 1999). "Bronchopulmonary segmental lavage with Surfaxin (KL(4)-surfactant) for acute respiratory distress syndrome". ...
Neonatal intensive care unit
Common diagnoses and pathologies in the NICU include: Anemia Apnea Bradycardia Bronchopulmonary dysplasia (BPD) Hydrocephalus ... Complications of extreme prematurity may include intracranial hemorrhage, chronic bronchopulmonary dysplasia (see Infant ...
Henrik Verder
... has been shown to successfully decrease the use of mechanical ventilation and lower the incidence of bronchopulmonary dysplasia ...
Piclamilast
... bronchopulmonary dysplasia and asthma. It is a second generation compound that exhibits structural functionalities of the PDE4 ...
BPD
Borderline personality disorder Bipolar disorder Brief psychotic disorder Biliopancreatic diversion Bronchopulmonary dysplasia ...
Plasmalogen
There is some evidence in humans that low plasmalogens are involved in the pathology of bronchopulmonary dysplasia, which is an ...
List of enzymes
Lysozyme's have also been associated with Bronchopulmonary dysplasia (BPD) in newborns and is a key factor in providing the ...
Chronic lung disease
... may refer to: Asthma Bronchopulmonary dysplasia Chronic obstructive pulmonary disease, including chronic ...
Siberian Husky
Hip dysplasia is not often found in this breed; however, as with many medium or larger-sized canines, it can occur. The ... bronchitis or bronchopulmonary ailments ("ski asthma"), and gastric erosions or ulcerations. Modern Siberian Huskies registered ... "OFA: Hip Dysplasia Statistics". Offa.org. Archived from the original on August 22, 2008. Retrieved February 2, 2009. Davis, M. ... with only two percent of tested Siberian Huskies showing dysplasia. Siberian Huskies used for sled racing may also be prone to ...
Bronchiolitis obliterans
... bronchopulmonary dysplasia), and exposure to toxic fumes. Toxins implicated in the condition include diacetyl, sulfur dioxide, ...
Ureaplasma urealyticum infection
... bronchopulmonary dysplasia and meningitis. U. urealyticum has been found to be present in amniotic fluid in women who have had ...
High-frequency ventilation
Pulmonary interstitial emphysema Intraventricular hemorrhage Necrotizing tracheobronchitis Bronchopulmonary dysplasia High- ... Pulmonary interstitial emphysema Intraventricular hemorrhage Necrotizing tracheobronchitis Bronchopulmonary dysplasia ...
Neonatology
... septal defect Atrioventricular septal defect Benign neonatal hemangiomatosis Brachial plexus injury Bronchopulmonary dysplasia ...
List of MeSH codes (C16)
... septo-optic dysplasia MeSH C16.131.740.195 - bronchogenic cyst MeSH C16.131.740.214 - bronchopulmonary sequestration MeSH ... bronchopulmonary dysplasia MeSH C16.614.521.450 - leukomalacia, periventricular MeSH C16.614.521.563 - respiratory distress ... ectodermal dysplasia MeSH C16.131.260.800.240.350 - focal dermal hypoplasia MeSH C16.131.260.800.300 - fragile X syndrome MeSH ... ectodermal dysplasia MeSH C16.320.180.800.240.350 - focal dermal hypoplasia MeSH C16.320.180.800.300 - fragile X syndrome MeSH ...
List of diseases (B)
Chronic Bronchogenic cyst Bronchopulmonary amyloidosis Bronchopulmonary dysplasia Brown syndrome Brown-Séquard syndrome ... disorder Bone dysplasia Azouz type Bone dysplasia corpus callosum agenesis Bone dysplasia lethal Holmgren type Bone dysplasia ... tibial hypoplasia Brachydactyly type A1 Brachydactyly type A2 Brachydactyly type A3 Brachydactyly type A5 nail dysplasia ... Bonneman-Meinecke-Reich syndrome Bonnemann-Meinecke syndrome Bonnevie-Ullrich-Turner syndrome Book syndrome Boomerang dysplasia ...
Bronchopulmonary dysplasia: MedlinePlus Medical Encyclopedia
Bronchopulmonary dysplasia (BPD) is a long-term (chronic) lung condition that affects newborn babies who were either put on a ... Bronchopulmonary dysplasia (BPD) is a long-term (chronic) lung condition that affects newborn babies who were either put on a ... Bronchopulmonary dysplasia. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of ...
Nasal CPAP and surfactant for treatment of respiratory distress syndrome and prevention of bronchopulmonary dysplasia
Altered relaxation times in MRI indicate bronchopulmonary dysplasia | Thorax
Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia - Full Text View - ClinicalTrials.gov
Bronchopulmonary (BPD) dysplasia (yes/no) [ Time Frame: 36 weeks post menstrual age ]. Incidence of bronchopulmonary dysplasia ... Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia. The safety and scientific validity of this ... Pulmonary Hypertension Bronchopulmonary Dysplasia Drug: inhaled nitric oxide Drug: Placebo Phase 1 Phase 2 ... Prediction of bronchopulmonary dysplasia by postnatal age in extremely premature infants. Am J Respir Crit Care Med. 2011 Jun ...
Bronchopulmonary Dysplasia (BPD) | Dayton Children's Hospital
Bronchopulmonary Dysplasia (BPD). What Is Bronchopulmonary Dysplasia?. Bronchopulmonary dysplasia (BPD), sometimes called ... How Is Bronchopulmonary Dysplasia Treated?. No medical treatment can cure bronchopulmonary dysplasia right away. Treatment ... What Happens in Bronchopulmonary Dysplasia?. Babies arent born with the condition. It happens when a baby has been on oxygen ... Babies who are born very early or who have breathing problems after birth are at risk for bronchopulmonary dysplasia (brahn-ko- ...
L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia | Clinical Research Trial Listing ( Infant |...
L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia ... Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects up to 35% of very low birth weight infants (VLBW , 1500 ... oral L-citrulline clinically for the treatment of pediatric pulmonary hypertension associated with bronchopulmonary dysplasia ( ...
Pericardial effusion and pulmonary vein stenosis in severe bronchopulmonary dysplasia | ADC Fetal & Neonatal Edition
A female infant with antenatally diagnosed trisomy 21 was delivered at 27 weeks. She was intubated at birth and given surfactant. A day 3 echocardiogram three showed a structurally normal heart, but severe pulmonary hypertension (PH). She required oscillation, nitric oxide and inotropes. At 1 week, she developed necrotising enterocolitis (NEC) and a perforation requiring resection and ileostomy formation. A subsequent echocardiogram showed resolved PH. She was … ...
Bronchopulmonary Dysplasia | Riley Children's Health
Bronchopulmonary dysplasia (BPD), or preterm lung disease, is inflammation in the lungs of newborns, which the Riley pediatric ... Bronchopulmonary dysplasia (BPD) is also known as preterm lung disease. It is a condition that babies may be born with or ... Discover more information about bronchopulmonary dysplasia, including its causes, symptoms, and treatments and what it is like ... Visit the links below to learn more about Bronchopulmonary Dysplasia and find support services. ...
Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia. | California Perinatal...
Bronchopulmonary Dysplasia, Child, Preschool, Cognition, Female, Humans, Infant Behavior, Infant, Extremely Premature, Infant, ... OBJECTIVE: To characterize behavior of 2-year-old children based on the severity of bronchopulmonary dysplasia (BPD). ... Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia. ... Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia.. ...
Circulating endothelial progenitor cells in preterm infants with bronchopulmonary dysplasia<...
Circulating endothelial progenitor cells in preterm infants with bronchopulmonary dysplasia. Alessandro Borghesi, Margherita ... Circulating endothelial progenitor cells in preterm infants with bronchopulmonary dysplasia. / Borghesi, Alessandro; Massa, ... Rationale: The new form of bronchopulmonary dysplasia (BPD) is characterized by lung immaturity with disrupted alveolar and ... N2 - Rationale: The new form of bronchopulmonary dysplasia (BPD) is characterized by lung immaturity with disrupted alveolar ...
Vitamin E and bronchopulmonary dysplasia - McMaster Experts
Postnatal Cytomegalovirus Infection and the Risk of Bronchopulmonary Dysplasia
Bronchopulmonary Dysplasia Cohort Studies Cytomegalovirus Cytomegalovirus Infections Female Humans Infant Infant, Newborn ... To investigate the relationship between postnatal CMV infection and bronchopulmonary dysplasia (BPD) and mortality in a large, ... Title : Postnatal Cytomegalovirus Infection and the Risk of Bronchopulmonary Dysplasia Personal Author(s) : Kelly, Matthew S.; ...
IL-18R1 and IL-18RAP SNPs may be associated with bronchopulmonary dysplasia in African-American infants<...
IL-18R1 and IL-18RAP SNPs may be associated with bronchopulmonary dysplasia in African-American infants. In: Pediatric Research ... IL-18R1 and IL-18RAP SNPs may be associated with bronchopulmonary dysplasia in African-American infants. / Floros, Joanna; ... IL-18R1 and IL-18RAP SNPs may be associated with bronchopulmonary dysplasia in African-American infants. Pediatric Research. ... Dive into the research topics of IL-18R1 and IL-18RAP SNPs may be associated with bronchopulmonary dysplasia in African- ...
Metabolic rate and energy balance in infants with bronchopulmonary dysplasia - Fingerprint - Taipei Medical University
Respiratory Distress Syndrome: Background, Etiology, Epidemiology
Bronchopulmonary dysplasia. BPD is a chronic lung disease defined as a requirement for oxygen at a corrected gestational age of ... Effects of early treatment of preterm infants with low-dose inhaled nitric oxide (iNO) on bronchopulmonary dysplasia (BPD) ... Effects of inhaled nitric oxide (iNO) survival without bronchopulmonary dysplasia (BPD) for infants aged 7-21 days. iNO ... resulting in bronchopulmonary dysplasia (BPD). FiO2 = fraction of inspired oxygen; HMD = hyaline membrane disease; V/Q = ...
Bronchopulmonary Dysplasia: Practice Essentials, Background, Pathophysiology
Bronchopulmonary dysplasia (BPD) is a form of chronic lung disease that develops in preterm neonates treated with oxygen and ... encoded search term (Bronchopulmonary Dysplasia) and Bronchopulmonary Dysplasia What to Read Next on Medscape ... The pathogenesis of bronchopulmonary dysplasia remains complex and poorly understood. Bronchopulmonary dysplasia results from ... 7] The physiologic definition of bronchopulmonary dysplasia reduced the overall rate of bronchopulmonary dysplasia and reduced ...
Bronchopulmonary Dysplasia: Practice Essentials, Background, Pathophysiology
Bronchopulmonary dysplasia (BPD) is a form of chronic lung disease that develops in preterm neonates treated with oxygen and ... encoded search term (Bronchopulmonary Dysplasia) and Bronchopulmonary Dysplasia What to Read Next on Medscape ... The pathogenesis of bronchopulmonary dysplasia remains complex and poorly understood. Bronchopulmonary dysplasia results from ... 7] The physiologic definition of bronchopulmonary dysplasia reduced the overall rate of bronchopulmonary dysplasia and reduced ...
Montana Medical Home Portal - Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) is a form of chronic respiratory disease manifested by the persistent need for supplemental ... and vascular phenotypes associated with bronchopulmonary dysplasia, as well as non-bronchopulmonary dysplasia respiratory ... The Diagnosis of Bronchopulmonary Dysplasia in Very Preterm Infants. An Evidence-based Approach.. Am J Respir Crit Care Med. ... Bronchopulmonary dysplasia.. Am J Respir Crit Care Med. 2001;163(7):1723-9. PubMed abstract. This article summarizes a workshop ...
Infant Respiratory Distress Syndrome: What to know
Preeclampsia and risk of developing bronchopulmonary dysplasia in very preterm neonates</em>...
Preeclampsia and risk of developing bronchopulmonary dysplasia in very preterm neonates. F A Wilmink, J Reijnierse, I Reiss, E ... N2 - Introduction: Bronchopulmonary dysplasia (BPD) is still a serious and common complication of prematurity and significantly ... AB - Introduction: Bronchopulmonary dysplasia (BPD) is still a serious and common complication of prematurity and significantly ... Introduction: Bronchopulmonary dysplasia (BPD) is still a serious and common complication of prematurity and significantly ...
Impact of bronchopulmonary dysplasia on pulmonary function during childhood: a systematic review
Palavras-chave : bronchopulmonary dysplasia; lung diseases; infant; respiratory function testing; child. · resumo em Português ... Impact of bronchopulmonary dysplasia on pulmonary function during childhood: a systematic review. J. Hum. Growth Dev. [online ... INTRODUCTION: Bronchopulmonary dysplasia (BPD) is a multifactorial chronic lung disease that contributes to disruption of ...
The NLRP3 inflammasome is critically involved in the development of bronchopulmonary dysplasia<...
The pathogenesis of bronchopulmonary dysplasia (BPD), a devastating lung disease in preterm infants, includes inflammation, the ... The NLRP3 inflammasome is critically involved in the development of bronchopulmonary dysplasia. / Liao, Jie; Kapadia, Vishal S ... The NLRP3 inflammasome is critically involved in the development of bronchopulmonary dysplasia. Nature communications. 2015 Nov ... The NLRP3 inflammasome is critically involved in the development of bronchopulmonary dysplasia. In: Nature communications. 2015 ...
Modulations in breathing patterns during intermittent feeding in term infants and preterm infants with bronchopulmonary...
As infants with bronchopulmonary dysplasia (BPD) have difficulty maintaining adequate levels of oxygenation during rest, it was ... N2 - As infants with bronchopulmonary dysplasia (BPD) have difficulty maintaining adequate levels of oxygenation during rest, ... AB - As infants with bronchopulmonary dysplasia (BPD) have difficulty maintaining adequate levels of oxygenation during rest, ... abstract = "As infants with bronchopulmonary dysplasia (BPD) have difficulty maintaining adequate levels of oxygenation during ...
Underlying Medical Conditions Associated with Higher Risk for Severe COVID-19: Information for Healthcare Professionals | CDC
Treatment for bronchopulmonary dysplasia in premature infants shows promising results. | Cells4Life
Treatment for bronchopulmonary dysplasia in premature infants shows promising results.. Apr 28, 2021 , Blog, Other, Stem Cell ... Bronchopulmonary dysplasia is a form of lung disease, sometimes chronic, which affects newborn babies, it is most common in ... severe bronchopulmonary dysplasia, in infants born at 23 to 24 weeks who received the MSC transplant. In order to increase the ... to treat bronchopulmonary dysplasia (BPD) in premature infants has shown promising initial results, giving way to a larger ...
Intestine Transplantation
Airway administration of corticosteroids for prevention of bronchopulmonary dysplasia in premature infants: a meta-analysis...
... of corticosteroids for preventing bronchopulmonary dysplasia (BPD) in premature infants. We searched MEDLINE, EMBASE, CINAHL, ... Uncertainly prevails with regard to the use of inhalation or instillation steroids to prevent bronchopulmonary dysplasia in ... Funnel plot of bronchopulmonary dysplasia, death, and requirement for systemic steroids with the use of AACs or placebo, AACs: ... Bronchopulmonary dysplasia (BPD), defined as oxygen dependence at 36 weeks of postmenstrual age (PMA), is a severe ...
Genetic predisposing factors to bronchopulmonary dysplasia: preliminary data from a multicentre study
Bronchopulmonary dysplasia (BPD) is the most frequent chronic lung disease in preterm newborn infants. It is a multifactorial ... Bronchopulmonary dysplasia (BPD) is the most frequent chronic lung disease in preterm newborn infants. It is a multifactorial ... Genetic predisposing factors to bronchopulmonary dysplasia: preliminary data from a multicentre study. Somaschini M;Castiglioni ...
Neonatal Intensive Care Drug Therapy Update: A Bibliography | Article | NursingCenter
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants ... Corticosteroids in the prevention and management of bronchopulmonary dysplasia. Semin Neonatol. 2003 Feb;8(1):83-91. ... Nebulized pentoxifylline in successful treatment of five premature neonates with broncho-pulmonary dysplasia. Eur J Pediatr. ...
Infants with bronchopulmonary dysplasiaDevelopment of bronchopulmonary dysplasiaIncidence of bronchopulmonary dysplasiaPrevention of bronchopulmonary dysplasiaImprove survival without bronchopulmonary dysplasiaPrematurePrevent bronchopulmonary dysplasiaPathogenesis of bronchopulmonaryExtremely pretermPulmonarySeveritySevereCysticChronicPediatricsBirth WeightComplicationPneumoniaTreatmentRiskDiagnosisChestBabiesChildrenAnalysis
Infants with bronchopulmonary dysplasia4
- In addition, routinely monitor blood pressure, as infants with bronchopulmonary dysplasia can also develop systemic hypertension. (medscape.com)
- Infants with bronchopulmonary dysplasia have increased energy requirements. (medscape.com)
- As infants with bronchopulmonary dysplasia (BPD) have difficulty maintaining adequate levels of oxygenation during rest, it was decided to investigate how the additional respiratory demands associated with nutritive feeding disrupt their breathing rates. (ulster.ac.uk)
- Infants with bronchopulmonary dysplasia (BPD) who were born to Black mothers were significantly more likely to die or to have a longer hospital stay than infants of other ethnicities, based on data from more than 800 infants. (medscape.com)
Development of bronchopulmonary dysplasia3
- Introduction: The genetic contribution to the development of bronchopulmonary dysplasia (BPD) in prematurely born infants is substantial, but information related to the specific genes involved is lacking. (elsevier.com)
- The primary outcome was survival without development of bronchopulmonary dysplasia at postmenstrual age 36 weeks. (unicatt.it)
- The prolonged use of high concentrations of oxygen and mechanical ventilation are associated with the development of bronchopulmonary dysplasia and retinopathy of prematurity. (drugs.com)
Incidence of bronchopulmonary dysplasia3
- This is a single center, blinded, randomized control clinical trial to evaluate the effects of inhaled nitric oxide on the outcome of survival and incidence of bronchopulmonary dysplasia. (clinicaltrials.gov)
- We therefore tested the hypothesis that inhaled nitric oxide at a low concentration, started early and maintained for an extended period in babies with mild respiratory failure, might reduce the incidence of bronchopulmonary dysplasia. (unicatt.it)
- Despite the improvements in prevention of acute respiratory disease in preterm infants, the incidence of bronchopulmonary dysplasia (BPD) remains largely unchanged. (who.int)
Prevention of bronchopulmonary dysplasia3
- The Scandinavian approach is an effective combined treatment for respiratory distress syndrome (RDS) and prevention of bronchopulmonary dysplasia (BPD). (nih.gov)
- Cochrane Abstracts , Evidence Central , evidence.unboundmedicine.com/evidence/view/Cochrane/431687/all/Pentoxifylline_for_the_prevention_of_bronchopulmonary_dysplasia_in_preterm_infants:_Cochrane_systematic_review. (unboundmedicine.com)
- Inhaled nitric oxide for prevention of bronchopulmonary dysplasia in premature babies (EUNO): a randomised controlled trial. (unicatt.it)
Improve survival without bronchopulmonary dysplasia3
- Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia. (childrensmercy.org)
- Whether hydrocortisone treatment after the second postnatal week can improve survival without bronchopulmonary dysplasia and without adverse neurodevelopmental effects is unknown. (childrensmercy.org)
- INTERPRETATION: Early use of low-dose inhaled nitric oxide in very premature babies did not improve survival without bronchopulmonary dysplasia or brain injury, suggesting that such a preventive treatment strategy is unsuccessful. (unicatt.it)
Premature10
- Premature babies who need oxygen therapy for more than 28 days are considered to have bronchopulmonary dysplasia. (childrensdayton.org)
- Rationale: The new form of bronchopulmonary dysplasia (BPD) is characterized by lung immaturity with disrupted alveolar and capillary development after extremely premature birth, but the mechanism of impaired lung vascular formation is still not completely understood. (elsevier.com)
- Treatment for bronchopulmonary dysplasia in premature infants shows promising results. (cells4life.com)
- A Phase II trial investigating the use of umbilical cord blood mesenchymal stem cells (MSCs) to treat bronchopulmonary dysplasia (BPD) in premature infants has shown promising initial results, giving way to a larger Phase II study, focusing on a subset of babies who looked to have benefitted most from the therapy. (cells4life.com)
- Bronchopulmonary dysplasia is a form of lung disease, sometimes chronic, which affects newborn babies, it is most common in premature infants or those with a low birth weight the condition is though to be exacerbated or possibly brought on by prolonged mechanical ventilation to treat other respiratory symptoms 2 . (cells4life.com)
- The meta-analysis with sequential analysis was designed to evaluate the efficacy and safety of airway administration (inhalation or instillation) of corticosteroids for preventing bronchopulmonary dysplasia (BPD) in premature infants. (biomedcentral.com)
- Bronchopulmonary dysplasia (BPD), defined as oxygen dependence at 36 weeks of postmenstrual age (PMA), is a severe complications of extremely premature infants. (biomedcentral.com)
- BACKGROUND: In animal models, inhaled nitric oxide improved gas exchange and lung structural development, but its use in premature infants at risk of developing bronchopulmonary dysplasia remains controversial. (unicatt.it)
- Hyperoxic injury is also a cause of retinopathy of prematurity and considered an important trigger in bronchopulmonary dysplasia of premature infants (4,5). (cdc.gov)
- Noninvasive Inhaled Nitric Oxide Does Not Prevent Bronchopulmonary Dysplasia in Premature Newborns. (neonatalresearch.org)
Prevent bronchopulmonary dysplasia1
- Uncertainly prevails with regard to the use of inhalation or instillation steroids to prevent bronchopulmonary dysplasia in preterm infants. (biomedcentral.com)
Pathogenesis of bronchopulmonary1
- The pathogenesis of bronchopulmonary dysplasia (BPD), a devastating lung disease in preterm infants, includes inflammation, the mechanisms of which are not fully characterized. (uthscsa.edu)
Extremely preterm2
- Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia. (cpqcc.org)
- BACKGROUND: Bronchopulmonary dysplasia is a prevalent complication after extremely preterm birth. (childrensmercy.org)
Pulmonary4
- Bronchopulmonary dysplasia (BPD) is a multifactorial chronic lung disease that contributes to disruption of pulmonary development. (bvsalud.org)
- Dr. Abushahin has a particular interest in the area of Bronchopulmonary Dysplasia (BPD), Pulmonary Arterial Hypertension (PAH), Severe asthma and Cardiopulmonary Exercise Test in children (CPET). (sidra.org)
- He is the medical director of the pulmonary function laboratory, the leader of the flexible bronchoscopy service, the director of the Bronchopulmonary Dysplasia respiratory care program, and the director of the Palivizumab passive immunization program. (sidra.org)
- Additionally, the baby was given inhaled steroids, along with diuretic and Vitamin A, E supplements to prevent broncho-pulmonary dysplasia. (thereportingtoday.com)
Severity3
- To characterize behavior of 2-year-old children based on the severity of bronchopulmonary dysplasia (BPD). (cpqcc.org)
- MSCs have a potent paracrine effect that reduces inflammation which may prevent or reduce the severity of bronchopulmonary dysplasia. (cells4life.com)
- Study investigated the relationship between the severity-based definition of bronchopulmonary dysplasia (BPD), choice of treatment, and neurocognitive outcomes at age 3 and 8 years. (utah.edu)
Severe4
- Whilst there was no statistically meaningful difference between the placebo and treatment group on the primary outcomes of mortality or severe/ moderate BPD, subgroup analysis showed significant improvement from 53% to just 19% severe bronchopulmonary dysplasia, in infants born at 23 to 24 weeks who received the MSC transplant. (cells4life.com)
- Bronchopulmonary dysplasia (BPD) is a severe complication of prematurity that impacts survival and neurodevelopment. (siftdesk.org)
- The primary efficacy outcome was survival without moderate or severe bronchopulmonary dysplasia at 36 weeks of postmenstrual age, and the primary safety outcome was survival without moderate or severe neurodevelopmental impairment at 22 to 26 months of corrected age. (childrensmercy.org)
- CONCLUSIONS: In this trial involving preterm infants, hydrocortisone treatment starting on postnatal day 14 to 28 did not result in substantially higher survival without moderate or severe bronchopulmonary dysplasia than placebo. (childrensmercy.org)
Cystic1
- Scratch below the surface of commonly seen conditions plus bronchopulmonary dysplasia, cystic fibrosis, juvenile idiopathic arthritis, psoriasis, and multiple sclerosis. (pncb.org)
Chronic5
- Bronchopulmonary dysplasia (BPD) is a long-term ( chronic ) lung condition that affects newborn babies who were either put on a breathing machine after birth or were born very early (prematurely). (medlineplus.gov)
- Bronchopulmonary dysplasia (BPD), sometimes called chronic lung disease, is a problem with how a baby's lung tissue develops. (childrensdayton.org)
- Infants may recover completely or develop chronic lung damage, resulting in bronchopulmonary dysplasia (BPD). (medscape.com)
- Bronchopulmonary dysplasia (see the image below) is a form of chronic lung disease that develops in preterm neonates treated with oxygen and positive-pressure ventilation. (medscape.com)
- Bronchopulmonary dysplasia (BPD) is the most frequent chronic lung disease in preterm newborn infants. (unisr.it)
Pediatrics1
- In a study published in JAMA Pediatrics , the researchers, on behalf of the Bronchopulmonary Dysplasia Collaborative, reviewed data from 834 preterm infants enrolled in the BPD Collaborative registry from Jan. 1, 2015, to July 19, 2021, at eight centers in the United States. (medscape.com)
Birth Weight1
- NTproBNP is a useful early biomarker of bronchopulmonary dysplasia in very low birth weight infants. (siftdesk.org)
Complication1
- Introduction: Bronchopulmonary dysplasia (BPD) is still a serious and common complication of prematurity and significantly associated with respiratory morbidity in later life. (vumc.nl)
Pneumonia1
- Sometimes, bronchopulmonary dysplasia can happen if another problem affects a newborn's lungs, such as birth defects, heart disease, pneumonia, and other infections. (childrensdayton.org)
Treatment2
- No medical treatment can cure bronchopulmonary dysplasia right away. (childrensdayton.org)
- This document provides recommendations for monitoring and treatment of children in whom bronchopulmonary dysplasia (BPD) has been established and were discharged from the hospital, or who were older than 36 weeks of postmenstrual age. (bvsalud.org)
Risk3
- Preterm infants are at risk for early PH that is associated with high risk for bronchopulmonary dysplasia or death. (clinicaltrials.gov)
- Babies who are born very early or who have breathing problems after birth are at risk for bronchopulmonary dysplasia (brahn-ko-PUL-moh-nair-ee dis-PLAY-zhee-uh). (childrensdayton.org)
- The study found that transplanting umbilical cord blood MSCs into the tracheas of preterm infants at risk of bronchopulmonary dysplasia was feasible and safe. (cells4life.com)
Diagnosis1
- The role of systemic inflammatory indices in the diagnosis of bronchopulmonary dysplasia (BPD) is unknown. (bvsalud.org)
Chest1
- Chest radiograph of infant with bronchopulmonary dysplasia. (medscape.com)
Babies1
- Babies who need care in a hospital for bronchopulmonary dysplasia may need feedings of high-calorie formulas through a gastrostomy tube (G-tube) . (childrensdayton.org)
Children1
- Nine children had bronchopulmonary dysplasia (BPD). (europeanlung.org)
Analysis1
- Prolonged Tracheal Intubation and the Association Between Patent Ductus Arteriosus and Bronchopulmonary Dysplasia: A Secondary Analysis of the PDA-TOLERATE trial. (amedeo.com)