Bronchiolitis Obliterans
Cryptogenic Organizing Pneumonia
An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a "pneumonia-like" illness with cough, fever, malaise, fatigue, and weight loss. Pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. There is excessive proliferation of granulation tissue within small airways and alveolar ducts.
Lung Transplantation
Arteriosclerosis Obliterans
Bronchiolitis, Viral
Thromboangiitis Obliterans
A non-atherosclerotic, inflammatory thrombotic disease that commonly involves small and medium-sized arteries or veins in the extremities. It is characterized by occlusive THROMBOSIS and FIBROSIS in the vascular wall leading to digital and limb ISCHEMIA and ulcerations. Thromboangiitis obliterans is highly associated with tobacco smoking.
Collagen Type V
A fibrillar collagen found widely distributed as a minor component in tissues that contain COLLAGEN TYPE I and COLLAGEN TYPE III. It is a heterotrimeric molecule composed of alpha1(V), alpha2(V) and alpha3(V) subunits. Several forms of collagen type V exist depending upon the composition of the subunits that form the trimer.
Graft Rejection
Bronchoalveolar Lavage Fluid
Mediastinal Emphysema
Heart-Lung Transplantation
Lung
Respiratory Aspiration
Respiratory Function Tests
Prednisolone
Balanitis Xerotica Obliterans
Respiratory Syncytial Virus Infections
Transplantation, Homologous
Azithromycin
Biopsy
Nasal Lavage
Instillation, Drug
Radiation Pneumonitis
Radiography, Thoracic
Tomography, X-Ray Computed
Bronchi
Leukocyte Disorders
Forced Expiratory Volume
Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.
Postoperative Complications
Bronchoalveolar Lavage
Trachea
Costimulatory and Inhibitory T-Cell Receptors
A family of receptors that modulate the activation of T-LYMPHOCYTES by the T-CELL ANTIGEN RECEPTOR. The receptors are responsive to one or more B7 ANTIGENS found on ANTIGEN-PRESENTING CELLS and, depending upon the specific ligand-receptor combination, modulate a variety of T-cell functions such as the rate of clonal expansion, CELL SURVIVAL and cytokine production. Although commonly referred to as costimulatory receptors, some of the receptors have inhibitory effects such as inducing PERIPHERAL TOLERANCE.
Mustard Gas
Severe irritant and vesicant of skin, eyes, and lungs. It may cause blindness and lethal lung edema and was formerly used as a war gas. The substance has been proposed as a cytostatic and for treatment of psoriasis. It has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP-85-002, 1985) (Merck, 11th ed).
Primary Graft Dysfunction
Respiratory Syncytial Viruses
Pulmonary Fibrosis
Follow-Up Studies
Lung Diseases, Interstitial
A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Graft vs Host Disease
Oxygen Inhalation Therapy
Glucocorticoids
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
Treatment Outcome
Bone Marrow Transplantation
Risk Factors
Immunosuppressive Agents
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
Hematopoietic Stem Cell Transplantation
Transfer of HEMATOPOIETIC STEM CELLS from BONE MARROW or BLOOD between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). Hematopoietic stem cell transplantation has been used as an alternative to BONE MARROW TRANSPLANTATION in the treatment of a variety of neoplasms.
Increased risk of chronic graft-versus-host disease, obstructive bronchiolitis, and alopecia with busulfan versus total body irradiation: long-term results of a randomized trial in allogeneic marrow recipients with leukemia. Nordic Bone Marrow Transplantation Group. (1/382)
Leukemic patients receiving marrow from HLA-identical sibling donors were randomized to treatment with either busulfan 16 mg/kg (n = 88) or total body irradiation ([TBI] n = 79) in addition to cyclophosphamide 120 mg/kg. The patients were observed for a period of 5 to 9 years. Busulfan-treated patients had an increased risk of veno-occlusive disease (VOD) of the liver (12% v 1%, P =.01) and hemorrhagic cystitis (32% v 10%, P =.003). Acute graft-versus-host disease (GVHD) was similar in the two groups, but the 7-year cumulative incidence of chronic GVHD was 59% in the busulfan-treated group versus 47% in the TBI group (P =.05). Death from GVHD was more common in the busulfan group (22% v 3%, P <.001). Obstructive bronchiolitis occurred in 26% of the busulfan patients but in only 5% of the TBI patients (P <.01). Complete alopecia developed in 8 busulfan patients and partial alopecia in 17, versus five with partial alopecia in the TBI group (P <.001). Cataracts occurred in 5 busulfan-treated patients and 16 TBI patients (P =.02). The incidence of relapse after 7 years was 29% in both groups. Seven-year transplant-related mortality (TRM) in patients with early disease was 21% in the busulfan group and 12% in the TBI group. In patients with more advanced disease, the corresponding figures were 64% and 22%, respectively (P =.004). Leukemia-free survival (LFS) in patients with early disease was 68% in busulfan-treated patients and 66% in TBI patients. However, 7-year LFS in patients with more advanced disease was 17% in the busulfan group versus 49% in the TBI group (P <.01). In patients with chronic myeloid leukemia (CML) in first chronic phase, 7-year LFS was 72% and 83% in the two groups, respectively. (+info)Bilateral pneumothoraces with multiple bullae in a patient with asymptomatic bronchiolitis obliterans 10 years after bone marrow transplantation. (2/382)
A 16-year-old boy developed bronchiolitis obliterans (BO) 10 years after BMT for myelodysplastic syndrome. Although the patient complained of almost no dyspnea on exertion, he had mild hypercapnea with a markedly reduced forced expiratory volume of 0.32 l. Chest X-rays showed occasional bilateral minimal pneumothoraces, which is in accordance with the existence of multiple small bullae found on the pleural surface at video-assisted thoracic surgery. Histologic examination of the biopsied lung revealed BO. This case indicates that BO in adolescence following BMT and possible chronic GVHD may be masked because of lung immaturity at BMT, and BO after BMT may be associated with multiple pleural bullae. (+info)Constrictive bronchiolitis obliterans and paraneoplastic pemphigus. (3/382)
Constrictive bronchiolitis obliterans is rare, and the pathogenesis of the disease often remains unknown. This study reports on the case of a 38 yr-old female with constrictive bronchiolitis obliterans and paraneoplastic pemphigus associated with malignant lymphoma. The patient developed progressive obstructive lung disease. The chest radiograph showed almost normal lungs. Paraneoplastic pemphigus is a newly described syndrome in which patients have autoantibodies binding to some epithelia, including in the respiratory tract. The disease develops in association with non-Hodgkin's lymphomas or other malignant neoplasms. The case presented here suggests that constrictive bronchiolitis obliterans associated with paraneoplastic pemphigus may be one of the facets of autoimmune responses in this context. (+info)Peripheral blood allogeneic microchimerism in lung and cardiac allograft recipients. (4/382)
We have been investigating two parameters, donor antigen-specific hyporeactivity and peripheral blood allogeneic microchimerism, to determine whether these parameters will predict a chronic rejection-free state and which recipients may be candidates for steroid withdrawal. We have identified donor antigen-specific hyporeactivity for 33% (16/48) of lung and 23% (11/47) of heart recipients. For both organ groups, the hyporeactive subgroup experienced a lower incidence of chronic rejection. The probability of donor antigen-specific hyporeactivity predicting a chronic rejection-free state is 100% for lung and 91% for heart recipients. We have identified peripheral blood allogeneic microchimerism for 77% (20/26) of lung and 36% (9/25) of heart recipients tested at 12-18 months posttransplant. Donor antigen-specific hyporeactivity correlates with a critical level of donor cells in lung recipients; the probability of high peripheral blood allogeneic microchimerism levels predicting a chronic rejection-free state in lung recipients is 100%. The results in heart recipients are not as clear with a short-, but not long-term, trend of higher chimerism levels correlating with the development of donor antigen-specific hyporeactivity. These results illustrate the usefulness of immmune parameters to predict long-term graft outcome in an organ-specific manner. (+info)Persistent high BAL fluid granulocyte activation marker levels as early indicators of bronchiolitis obliterans after lung transplant. (5/382)
The major cause of mortality in the long-term in lung transplant recipients is chronic rejection. This is a fibroproliferative process in the small airways leading to obliterative bronchiolitis and progressive loss of lung function, both constituting the clinical entity bronchiolitis obliterans syndrome (BOS). Granulocyte activation has been implicated as one factor behind BOS. Granulocyte markers in bronchoalveolar lavage (BAL) fluid were prospectively and longitudinally studied in order to identify possible association with BOS. BAL fluid from 266 bronchoscopy procedures performed in twelve single lung, eight bilateral lung and five heart/lung transplant recipients were analysed. The majority (19 of 25) were studied for a period of 2 yrs after surgery. Myeloperoxidase (MPO), eosinophil cationic protein (ECP) and interleukin-8 (IL-8) levels were used as indirect markers of activation and attraction of granulocytes. Five patients developed BOS. Ninety-eight episodes of acute rejection, nine of bacterial infection, 19 of cytomegalovirus pneumonitis, nine of Pneumocystis carinii infection, two of aspergillus infection and two of respiratory syncytial virus infection were diagnosed. BOS patients had significantly higher mean levels of MPO, ECP and IL-8 compared to patients without BOS, irrespective of acute rejection status. Over time, the five patients with BOS had significantly elevated BAL fluid levels of MPO and ECP as well as neutrophil percentages, and in four patients this increase preceded the clinical diagnosis of BOS by several months. Elevated bronchoalveolar lavage fluid neutrophil percentage as well as levels of the granulocyte activation markers myeloperoxidase and eosinophil cationic protein appear to be early signs of development of BOS in lung transplant recipients. (+info)Airway neutrophilia in stable and bronchiolitis obliterans syndrome patients following lung transplantation. (6/382)
BACKGROUND: The bronchiolitis obliterans syndrome (BOS) remains the major constraint on the long term success of lung transplantation. Neutrophils have been associated with fibrosing lung conditions and have been noted to be increased in the bronchoalveolar lavage (BAL) fluid of patients with BOS. METHODS: This study was undertaken to examine neutrophil accumulation in the BAL fluid, airway wall and lung parenchyma, as well as levels of interleukin (IL)-8 in the BAL fluid, in normal controls and lung transplant recipients with and without BOS. Bronchoscopic examination included endobronchial biopsy (EBB), BAL fluid, and transbronchial biopsy (TBB) sampling. Tissue neutrophils were identified by neutrophil elastase staining on 3 microm paraffin biopsy sections and quantified by computerised image analyser. IL-8 levels were measured in unconcentrated BAL fluid by ELISA. RESULTS: Compared with controls, airway wall neutrophilia was increased in both stable lung transplant recipients and those with BOS (p<0.05). BAL neutrophils and IL-8 levels were also increased in both groups of transplant recipients compared with controls (p<0.01), the levels being significantly higher in the BOS group (p<0.01). Neutrophil numbers in the lung parenchyma were not significantly different between the two groups of lung transplant recipients. CONCLUSION: Increased levels of neutrophils are present in the airway wall and BAL fluid of lung transplant recipients with and without BOS. BAL fluid levels of IL-8 are also increased, raising the possibility that neutrophils and/or IL-8 may play a part in the pathogenesis of BOS following lung transplantation. (+info)Clinical and radiological characteristics of lung disease in inflammatory bowel disease. (7/382)
The pulmonary associations of inflammatory bowel disease (IBD) are poorly characterized. The clinical, physiological and high-resolution computed tomographic thorax characteristics of the lung disease in patients with IBD presenting with respiratory symptoms are described. Detailed clinical information was obtained and standard pulmonary physiological tests and thorax high-resolution computed tomography performed on 14 patients with ulcerative colitis (UC) and three with Crohn's disease (CD), 10 male, aged 38-83 yrs. Respiratory symptoms had been present for 2-50 yrs and extraintestinal manifestations were present in three (17.6%). Normal pulmonary physiology (six patients) was associated with the high resolution computed tomographic changes of bronchiectasis, mosaic perfusion and air trapping suggestive of obliterative bronchiolitis and a pattern of centrilobular nodules and branching linear opacities ("tree in bud" appearance) suggestive of either cellular bronchiolitis or bronchiolectasis with mucoid secretions. Bronchiectasis was found in 13 patients (11 UC, 2 CD), 11 had air trapping and five had a "tree in bud" appearance on computed tomography. One patient had a predominantly peripheral reticular pattern at the lung bases similar to that found in cryptogenic fibrosing alveolitis and one patient had a mixed reticular and ground-glass pattern in the midzones with a patchy distribution in the central and peripheral portions of the lungs with air trapping. Eleven patients (three with alveolitis) exhibited a clinical and/or physiological response to steroids. Pulmonary abnormalities in ulcerative colitis and Crohn's disease can present years after the onset of the bowel disease and can affect any part of the lungs. Early recognition is important as they can be strikingly steroid-responsive. (+info)B7-1, B7-2 and class II MHC molecules in idiopathic pulmonary fibrosis and bronchiolitis obliterans-organizing pneumonia. (8/382)
Interstitial lung diseases are thought to be associated with the infiltration of activated T-lymphocytes. To induce an effective immune response, antigen-presenting cells have to not only present antigenic peptide with major histocompatibility complex (MHC) molecules to T-lymphocytes but also express B7 molecules. Therefore, the expression of B7-1, B7-2 and class II MHC molecules was investigated in lung tissues from patients with idiopathic pulmonary fibrosis (IPF) and bronchiolitis obliterans-organizing pneumonia (BOOP), and in normal lung parenchyma as a control, using immunohistochemical localization. B7-1 and B7-2 were aberrantly expressed in bronchiolar and alveolar epithelial cells, and class II MHC molecules were also aberrantly expressed in bronchiolar epithelial cells in IPF. B7-1 was aberrantly expressed in bronchiolar epithelial cells in BOOP. There was no significant difference in the expression of these proteins in alveolar macrophages between IPF and control subjects. However, B7-2 and class II MHC molecule expression in alveolar macrophages was decreased in BOOP compared with that in control subjects. Expression of CD28 and CTLA4, receptors for B7 molecules, was detected in infiltrating lymphocytes in lung tissues in IPF and BOOP. It was concluded that bronchiolar and alveolar epithelial cells may actively participate in the pathophysiology of idiopathic pulmonary fibrosis through the aberrant expression of B7 and class II major histocompatibility complex molecules. The dysregulation of these molecules in epithelial cells may lead to the activation of autoreactive T-lymphocytes, which might contribute to the pathogenesis of fibrosing lung diseases. (+info)Bronchiolitis obliterans nach lungentransplantation<...
Bronchiolitis Obliterans Syndrome Market Size, Epidemiology, Treatment, Therapies and Companies by DelveInsight - Imphal News...
Genetic regulation of rejection and survival following human lung transplantation by the innate immune receptor CD14<...
2002 Staging System of the International Society for Heart and Lung Transplantation for Bronchiolitis Obliterans Syndrome (BOS)...
The macrolide clarithromycin inhibits experimental posttransplant bronchiolitis obliterans - Zurich Open Repository and Archive
Efficacy of Azithromycin to Prevent Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation ...
Targeted Therapy of Bronchiolitis Obliterans Syndrome - Full Text View - ClinicalTrials.gov
Experimental bronchiolitis obliterans induced by in vivo HVJ-liposome- mediated endothelin-1 gene transfer<...
Lung transplant survival is usually limited by obliterative bronchiolitis (OB), but | High-Throughput Screen for the Chemical...
bronchiolitis obliterans
Double lung, unlike single lung transplantation might provide a protective effect on mortality and bronchiolitis obliterans...
Anti-allergic agent tranilast decreases development of obliterative airway disease in rat model of heterotopic tracheal...
Secondary bronchiolitis obliterans organizing pneumonia during treatment of chronic hepatitis C: role of pegylated interferon...
Bronchiolitis obliterans organizing pneumonia
The impact of traffic air pollution on bronchiolitis obliterans syndrome and mortality after lung transplantation | Thorax
MEDLINE - Resultado p gina 1
Staging of Bronchiolitis Obliterans Syndrome Using Home Spirometry: BOS staging
Bronchiolitis obliterans organizing pneumonia and ulcerative colitis after allogeneic bone marrow transplantation. - Baron...
The Role of Aspergillus in the Pathogenesis of Bronchiolitis Obliterans Syndrome - Stephen Weigt
Successful Extracorporeal Life Support for Life-threatening Hypercapnia with Bronchiolitis Obliterans after Allogeneic...
Bronchiolitis obliterans organizing pneumonia - encyclopedia article - Citizendium
Pulmonary Pathology
Bronchiolitis obliterans
Bronchiolitis Obliterans Causes, Symptoms and Treatment
PPT - Bronchiolitis Obliterans Organizing Pneumonia PowerPoint Presentation - ID:5710055
Bronchiolitis fibrosa obliterans | Article about bronchiolitis fibrosa obliterans by The Free Dictionary
Association between a Single Donor TARC/CCL17 Promotor Polymorphism and Obstructive Chronic Lung Allograft Dysfunction after...
JCI -
Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome
Which drug to prevent lung transplant rejection provides best results with fewest adverse effects? | Cochrane
Obliterative bronchiolitis - RightDiagnosis.com
With the current advances in technology as little as a si - dryslip info
Zambon to buy Sofinnovas inhalation therapy firm Breath Therapeutics - DEC Research News
Stitching and switching: the impact of discontinuous lung function reference equations | European Respiratory Society
Lirias: Macrolides Inhibit IL17-induced IL8 and 8-isoprostane Release from Human Airway Smooth Muscle Cells
Article abstract | Annals of Transplantation
Case 28--Radiology
E-Cigarettes and Popcorn Lung - NaturalPath
8:27 am
Molecules | Free Full-Text | Hyaluronic Acid-Decorated Liposomes as Innovative Targeted Delivery System for Lung Fibrotic Cells
Quiz case 6<...
Pinwheels raise funds for childhood lung disease - Sun Lakes Splash
Systemic uptake, albumin and hemoglobin binding of [14C]2,3-butanedione administered by intratracheal instillation in male...
Bronchiolitis obliterans organizing pneumonia and Sjögrens syndrome. - PubMed - NCBI
Bronchiolitis Obliterans Organizing Pneumonia/Cryptogenic Organizing Pneumonia
Bronchiolitis obliterans organizing pneumonia with migratory pulmonary infiltrates. - PubMed - NCBI
Lung perfusion scintigraphy to detect chronic lung allograft dysfunction after living-donor lobar lung transplantation - Yamane...
Lung transplantation for bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation: a single-center...
Lung transplantation: Chronic allograft dysfunction and establishing immune tolerance<...
Stage I adenocarcinoma presenting in the pneumonectomy specimen at the time of single lung transplantation<...
bronchiolitis obliterans syndrome | Transplant Now
Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation | Protocol
Air pollution and traffic linked to deaths and organ rejection in lung transplant patients
Feasibility and Reliability of Home-based Spirometry Telemonitoring in Allogeneic Hematopoietic Cell Transplant Recipients -...
PubMed Lung Transplant | Transplant Professional Portal
Respiratory Viral Infections in Lung Transplantation Webinar | American Society of Transplantation
A cross-sectional study of lung function and respiratory symptoms among chemical workers producing diacetyl for food...
Inhaled nitric oxide during anesthesia for bilateral single lung transplantation. Case report - Minerva Anestesiologica 1998...
Cryptogenic Organizing Pneumonia (COP) - Renal and Urology News
Rapidly progressive Bronchiolitis Obliterans Organising Pneumonia presenting with pneumothorax, persistent air leak, acute...
Bronchiolitis obliterans - Cancer Therapy Advisor
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Pneumotox » Drug » IV.c - Obliterative bronchiolitis (see also IVn)
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Acid Reflux Surgery Could Help Prevent Rejection in Lung Transplant Patients
Automatic event detection in lung transplant recipients based on home monitoring of Spirometry and symptoms<...
CD8+ T-cell maturation following lung transplantation: the dif...
119: Dissecting CMV-Specific Immunity in High-Risk Lung Transplant Recipients: Differences between the Lung Allograft and Blood...
Recovery after lung transplantation from a patient perspective - proposing a new framework
Study suggests need for renal protective care in pediatric lung transplant patients | EurekAlert! Science News
EURORAD - Radiologic Teaching Files
Peripheral Carcinoid Tumorlets With Neuroendocrine Cell Hyperplasia (NECH) and Obliterative Bronchiolitis (OB) - Oxford Medicine
Bronchiolar disease in rheumatoid arthritis
Multi Breath Nitrogen Washout (MBNW) as a Measure of Small Airway Function in Patients With Respiratory Disease | Clinical...
Popcorn Lung: A Dangerous Risk of Flavored E-Cigarettes | American Lung Association
Popcorn Lung® Lawsuit | Lawyer, Attorney
Pediatric Lung Disorders - UMass Memorial Medical Center - UMass Memorial Health Care
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Case 10--Answer 2
Recent trends in lung transplantation: the University of Minnesota experience.<...
Recent trends in lung transplantation: the University of Minnesota experience.<...
Mouse monoclonal to CD4/CD25 FITC/PE) - Gremlin is a Key Pro-fibrogenic Factor in Chronic Pancreatitis
Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation | Thorax
Health-related quality of life and stress-related posttransplant trajectories of lung transplant recipients: a three-year...
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LSHTM Research Online
JCI -
Foxp3+ T lymphocytes: immune regulators within the lung allograft
Swyer-James Syndrome Imaging: Overview, Radiography, Computed Tomography
Who may need a lung transplant?
Gary R. Epler
Gary Epler did research on the Bronchiolitis Obliterans Organizing Pneumonia which is inflammatory bronchiolitis obliterans ... "Bronchiolitis Obliterans Organizing Pneumonia". NORD (National Organization for Rare Disorders). Retrieved 2019-07-31. Ferkol, ... "Bronchiolitis Obliterans Organizing Pneumonia". New England Journal of Medicine. 312 (3): 152-158. doi:10.1056/ ...
High-resolution computed tomography
The major pulmonary complication is bronchiolitis obliterans, which may be a sign of lung graft rejection. HRCT has better ... Airways diseases, such as emphysema or bronchiolitis obliterans, cause air trapping on expiration, even though they may cause ... Khan AN, Hanley S, Macdonald S, Chandramohan M, Ghanem SA, Irion KL (6 January 2017). "Imaging in Bronchiolitis Obliterans ... Chan A, Allen R (March 2004). "Bronchiolitis obliterans: an update". Current Opinion in Pulmonary Medicine. 10 (2): 133-41. doi ...
Idiopathic interstitial pneumonia
... respiratory bronchiolitis; BIP=bronchiolitis obliterans interstitial pneumonia; OP=organizing pneumonia; LIP=lymphoid ...
Activated charcoal (medication)
Bronchiolitis obliterans after aspiration of activated charcoal". Chest. 96 (3): 672-4. doi:10.1378/chest.96.3.672. PMID ...
Activated carbon
Bronchiolitis obliterans after aspiration of activated charcoal". Chest. 96 (3): 672-4. doi:10.1378/chest.96.3.672. PMID ...
Papaverine
Induced Bronchiolitis Obliterans: From Botanical Studies to Toxicology". Evid Based Complement Alternat Med. 2015: 1-7. doi: ... Papaverine in the plant Sauropus androgynus is linked to bronchiolitis obliterans. Papaverine is available as a conjugate of ...
Safety of electronic cigarettes
Diacetyl and acetyl propionyl are associated with bronchiolitis obliterans. A 2018 PHE report stated that the e-cigarette ... A 2014 case report observed the correlation between sub-acute bronchiolitis and vaping. After quitting vaping the symptoms ...
Flock worker's lung
Occasionally, desquamative interstitial pneumonia and bronchiolitis obliterans organizing pneumonia can be seen. Other symptoms ... The typical histopathology in flock worker's lung is bronchiolocentric interstitial pneumonitis and lymphocytic bronchiolitis ...
Lung transplantation
Such chronic rejection presents itself as bronchiolitis obliterans, or less frequently, atherosclerosis. These statistics are ...
Sauropus androgynus
Consumption of Sauropus androgynus has been reported as being associated with bronchiolitis obliterans. The leaves are safe to ... "Outbreak of Bronchiolitis obliterans Associated with Consumption of Sauropus androgynus in Japan - Alert of Food-Associated ... "Outbreak of bronchiolitis obliterans associated with consumption of Sauropus androgynus in Taiwan". The Lancet. 348 (9020): 83- ...
Transplant rejection
Airflow obstruction not ascribable to other cause is labeled bronchiolitis obliterans syndrome (BOS), confirmed by a persistent ... June 2007). "Course of FEV(1) after onset of bronchiolitis obliterans syndrome in lung transplant recipients". American Journal ... "Immune mechanisms in the pathogenesis of bronchiolitis obliterans syndrome after lung transplantation". Pediatric ...
Diacetyl
Acetylpropionyl, a similar diketone Acetoin Bronchiolitis obliterans Merck Index (11th ed.). p. 2946. Eriks K, Hayden TD, Yang ... 46 (3): 385-8. Merriam-Webster Medical Dictionary > bronchiolitis obliterans Retrieved on August, 2010 Harber P, Saechao K, ... has been associated with bronchiolitis obliterans, a rare and life-threatening form of non-reversible obstructive lung disease ...
Polyhexamethylene guanidine
Merriam-Webster Medical Dictionary > bronchiolitis obliterans Retrieved on August, 2010 Lee Hyun-jeong for the Korea Herald. ... along with bronchiolitis obliterans, an often fatal form of non-reversible obstructive lung disease in which the bronchiole are ...
Anti-Jo1
Kalenian M; Zweiman B (March 1997). "Inflammatory myopathy, bronchiolitis obliterans/organizing pneumonia, and anti-Jo-1 ...
Bronchiole
Diseases of the bronchioles include asthma, bronchiolitis obliterans, respiratory syncytial virus infections, and influenza. ... The medical condition of inflammation of the bronchioles is termed bronchiolitis. Cross sectional cut of primary bronchiole ... Friedman JN, Rieder MJ, Walton JM (November 2014). "Bronchiolitis: Recommendations for diagnosis, monitoring and management of ...
Rheumatoid lung disease
This is more common in cases of bronchiolitis obliterans, pulmonary fibrosis, or pulmonary hypertension. Most complications are ... women Rheumatoid-associated interstitial lung disease Bronchiolitis obliterans organizing pneumonia Obliterative bronchiolitis ... pleural thickening or effusion interstitial fibrosis bronchiectasis bronchiolitis obliterans large rheumatoid nodules single or ... follicular bronchiolitis small centrilobular nodules or tree-in-bud rare Caplan syndrome Echocardiogram (may show pulmonary ...
Artificial butter flavoring
... "flavorings-related bronchiolitis obliterans" or diacetyl-induced bronchiolitis obliterans. People who work with flavorings that ... The lung disease bronchiolitis obliterans is attributed to prolonged exposure to diacetyl, e.g. in an industrial setting. ... In the year 2000, eight cases of bronchiolitis obliterans were detected in former employees of a microwave popcorn plant. Many ... Other studies also found cases of bronchiolitis obliterans in workers at 4 other microwave popcorn production facilities. ...
Flavored tobacco
Diacetyl and acetyl propionyl are associated with bronchiolitis obliterans ("popcorn lung"), a serious lung disease. A 2015 ...
George Born
In 2008, Born was diagnosed with bronchiolitis obliterans, a rare and non-reversible lung disease . He died in Boulder, ...
Inflammatory bowel disease
... and bronchiolitis obliterans organizing pneumonia (BOOP) have also been reported. Diagnosis is generally by assessment of ... "A case of ulcerative colitis complicated with bronchiolitis obliterans organizing pneumonia (BOOP) and air leak syndrome". The ...
Classification of pneumonia
Bronchiolitis obliterans organizing pneumonia (BOOP) is caused by inflammation of the small airways of the lungs. It is also ...
Pemphigus
... causing bronchiolitis obliterans (constrictive bronchiolitis). Though much less frequent, it is still found the most in the ... cocktail of immunosuppressant drugs is sometimes used in an attempt to halt the rapid progression of bronchiolitis obliterans, ...
Inhaled ciclosporin
The condition is aptly known as bronchiolitis obliterans and clinically is diagnosed as bronchiolitis obliterans syndrome (BOS ...
Interleukin 13
IL-13 is the dominant effector in toxin, infection, allergic, and post-transplant bronchiolitis obliterans models of fibrosis. ...
Paraneoplastic pemphigus
It manifests as dyspnea and progresses to bronchiolitis obliterans (non-reversible obstructive lung disease) via an unknown ...
Dicarbonyl
Diacetyl is known to cause the lung disease bronchiolitis obliterans in those individuals exposed to it in an occupational ...
Adenovirus infection
Up to one in five infants with bronchiolitis will have adenovirus infection, which can be severe. Bronchiolitis obliterans is ... Severe adenovirus pneumonia also may result in bronchiolitis obliterans, a subacute inflammatory process in which the small ... Other respiratory complications include acute bronchitis, bronchiolitis and acute respiratory distress syndrome. It may cause ...
Mycoplasma pneumoniae
... and bronchiolitis obliterans. Extrapulmonary symptoms such as autoimmune responses, central nervous system complications, and ...
Pneumonia
This may include, among others: empyema, lung abscess, bronchiolitis obliterans, acute respiratory distress syndrome, sepsis, ... respiratory bronchiolitis interstitial lung disease, and usual interstitial pneumonia. Lipoid pneumonia is another rare cause ...
Acute inhalation injury
... some patients develop bronchiolitis obliterans progressing to ARDS. Bronchiolitis obliterans with organized pneumonia can ensue ... and only intensely exposed victims showed signs like bronchiolitis obliterans in the distal part. Secondary effects of sulfur ... Irritant gas exposures predominantly affect the airways, causing tracheitis, bronchitis, and bronchiolitis. Other inhaled ... are more likely to cause severe bronchiolitis, and often have a lag of ≥ 12 h before symptoms of pulmonary edema develop. Acute ...
Air trapping
It is observed in obstructive lung diseases such as asthma, bronchiolitis obliterans syndrome and chronic obstructive pulmonary ...
Diffuse panbronchiolitis
... additional forms of primary bronchiolitis include bronchiolitis obliterans, follicular bronchiolitis, respiratory bronchiolitis ... DPB and bronchiolitis obliterans are two forms of primary bronchiolitis. Specific overlapping features of both diseases include ... DPB is classified as a form of "primary bronchiolitis", which means that the underlying cause of bronchiolitis is originating ... Unlike DPB, bronchiolitis that is not considered "primary" would be associated with diseases of the larger airways, such as ...
Nitrogen dioxide poisoning
Meanwhile, permanent mild dysfunction may result from bronchiolitis obliterans and could manifest as abnormal flow at 50 to 70 ... Illness resulting from acute exposure is usually not fatal although some exposure may cause bronchiolitis obliterans, pulmonary ... Complications from prolong exposure includes bronchiolitis obliterans and other secondary infections such as pneumonia due to ... mechanical ventilation and intubation may be necessary and if bronchiolitis obliterans develop within 2 to 6 weeks of nitrogen ...
Swyer-James syndrome
As a result of childhood bronchiolitis obliterans, typically following adenovirus infection, there is a reduction in blood ... Swyer-James syndrome is a manifestation of postinfectious obliterative bronchiolitis. In SJS, the involved lung or portion of ...
Occupational lung disease
Bronchiolitis obliterans, also known as constrictive bronchiolitis or obliterative bronchiolitis is a respiratory disease ... bronchiolitis obliterans, inhalation injury, interstitial lung diseases (such as pneumoconiosis, hypersensitivity pneumonitis, ... Barker, Alan F.; Bergeron, Anne; Rom, William N.; Hertz, Marshall I. (2014). "Obliterative Bronchiolitis". New England Journal ... can inflame bronchial epithelium and cause bronchiolitis, hemorrhagen, and pulmonary edema.[citation needed] Chronic Aspiration ...
Pulmonary toxicity
... bronchiolitis obliterans organising pneumonia, BOOP), ARDS (acute respiratory distress syndrome), solitary pulmonary mass (even ...
Conagra Brands
... due to cases of the potentially fatal disease bronchiolitis obliterans or "Popcorn Workers's Lung" appearing among plant ...
Erlotinib
... epidermal necrolysis ocular disorders corneal lesions Pulmonary toxicity interstitial pneumonitis bronchiolitis obliterans with ...
Bronchiolitis obliterans
... when it occurs following a lung transplant is known as bronchiolitis obliterans syndrome (BOS). BOS is ... Bronchiolitis obliterans (BO), also known as obliterative bronchiolitis, constrictive bronchiolitis and popcorn lung, is a ... Missouri developed bronchiolitis obliterans. Due to this event, bronchiolitis obliterans began to be referred to in the popular ... "bronchiolitis obliterans" used first by Reynaud in 1835. Bronchiolitis obliterans results in worsening shortness of breath, ...
List of MeSH codes (C08)
... bronchiolitis MeSH C08.127.446.135.140 - bronchiolitis obliterans MeSH C08.127.446.135.140.200 - bronchiolitis obliterans ... bronchiolitis obliterans MeSH C08.381.495.146.135.140.200 - bronchiolitis obliterans organizing pneumonia MeSH C08.381.495.146. ... bronchiolitis obliterans MeSH C08.381.483.187.200 - bronchiolitis obliterans organizing pneumonia MeSH C08.381.483.250 - ... bronchiolitis MeSH C08.730.099.135.321 - bronchiolitis, viral MeSH C08.730.099.567 - bronchitis, chronic MeSH C08.730.265.320 ...
Popcorn (disambiguation)
... an informal name for bronchiolitis obliterans (BO), a lung disease Popcorn noise, a burst noise of electronic components ...
Ciclosporin
... in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans" at ...
Averill A. Liebow
... bronchiolitis obliterans interstitial pneumonia and diffuse alveolar damage, desquamative interstitial pneumonia, lymphocytic ...
List of diseases (B)
Bronchiectasis Bronchiectasis oligospermia Bronchiolitis obliterans with obstructive pulmonary disease Bronchiolotis obliterans ...
International Flavors & Fragrances
IFF has been involved in several lawsuits relating to cases of bronchiolitis obliterans allegedly resulting from exposure to ...
Chest radiograph
... bronchiolitis obliterans organizing pneumonia) lung volume increased (e.g., Langerhans cell histiocytosis, ...
Bronchiolitis Obliterans Organizing Pneumonia (BOOP) Imaging: Practice Essentials, Radiography, Computed Tomography
... the qualifying term bronchiolitis obliterans (BO) is added. ... Linear opacities on HRCT in bronchiolitis obliterans organising ... Bronchiolitis Obliterans Organizing Pneumonia (BOOP) Imaging * Sections Bronchiolitis Obliterans Organizing Pneumonia (BOOP) ... encoded search term (Bronchiolitis Obliterans Organizing Pneumonia (BOOP) Imaging) and Bronchiolitis Obliterans Organizing ... Bronchiolitis Obliterans Organizing Pneumonia (BOOP) Imaging Updated: Mar 16, 2021 * Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, ...
Bronchiolitis obliterans - Wikipedia
Bronchiolitis obliterans when it occurs following a lung transplant is known as bronchiolitis obliterans syndrome (BOS). BOS is ... Bronchiolitis obliterans (BO), also known as obliterative bronchiolitis, constrictive bronchiolitis and popcorn lung, is a ... Missouri developed bronchiolitis obliterans. Due to this event, bronchiolitis obliterans began to be referred to in the popular ... "bronchiolitis obliterans" used first by Reynaud in 1835. Bronchiolitis obliterans results in worsening shortness of breath, ...
PARI Sees Successful Phase Ib Clinical Results for Bronchiolitis Obliterans Drug | RT
PARI Sees Successful Phase Ib Clinical Results for Bronchiolitis Obliterans Drug. Jun 3, 2009 , Clinical , ... This has the potential to prevent and treat bronchiolitis obliterans in a more efficient way compared to current oral standard ... inhaled liposomal cyclosporine A for the prevention and treatment of bronchiolitis obliterans from PARI Pharma, Monterey, Calif ...
Bronchiolitis obliterans<...
title = "Bronchiolitis obliterans",. author = "McLoud, {T. C.} and Epler, {G. R.} and Colby, {T. V.} and Gaensler, {E. A.} and ... McLoud, T. C., Epler, G. R., Colby, T. V., Gaensler, E. A., & Carrington, C. B. (1986). Bronchiolitis obliterans. Radiology, ... McLoud, TC, Epler, GR, Colby, TV, Gaensler, EA & Carrington, CB 1986, Bronchiolitis obliterans, Radiology, vol. 159, no. 1, ... Bronchiolitis obliterans. / McLoud, T. C.; Epler, G. R.; Colby, T. V. et al. ...
IMSEAR at SEARO: Bronchiolitis obliterans following measles.
Occupational Epidemiology and the National Institute for Occupational Safety and Health
Example: Bronchiolitis Obliterans in Workers at a Microwave-Popcorn Plant In 2002, Kathleen Kreiss, a NIOSH scientist and ... Kreiss K. Flavoring-related bronchiolitis obliterans. Curr Opin Allergy Immunol 2007;7:162--7. ... and colleagues reported an outbreak of bronchiolitis obliterans in workers at a microwave-popcorn production plant that used ... Kreiss K, Goma A, Kullman G, Fedan K, Simoes E, Enright P. Clinical bronioloitis obliterans in workers at a microwave-popcorn ...
Posttransplant bronchiolitis obliterans syndrome is associated with bronchial epithelial to mesenchymal transition
... ... Bronchiolitis obliterans syndrome (BOS) compromises lung transplant outcomes and is characterised by airway epithelial damage ... Posttransplant bronchiolitis obliterans syndrome is associated with bronchial epithelial to mesenchymal transition. American ... The airway epithelium is a direct source of matrix degrading enzymes in bronchiolitis obliterans syndrome ...
Clinical Impact of Community‐Acquired Respiratory Viruses on Bronchiolitis Obliterans After Lung Transplant
Bronchiolitis Obliterans Cohort Studies Community-Acquired Infections Female Graft Rejection Humans Lung Transplantation Male ... Clinical Impact of Community‐Acquired Respiratory Viruses on Bronchiolitis Obliterans After Lung Transplant. ... Increased Respiratory Disease Mortality at a Microwave Popcorn Production Facility with Worker Risk of Bronchiolitis Obliterans ... Title : Clinical Impact of Community‐Acquired Respiratory Viruses on Bronchiolitis Obliterans After Lung Transplant Personal ...
Status Asthmaticus Differential Diagnoses
Bronchiolitis obliterans and usual interstitial pneumonia. A comparative clinicopathologic study
... Academic Article ... Bronchiolitis obliterans had a more acute onset often associated with fever, while the presentation of usual interstitial ... The fibrosis in bronchiolitis obliterans was composed of proliferating fibroblasts, compared to collagen deposition in usual ... Three individuals with bronchiolitis obliterans (12.5%) died of progressive disease, compared to 10 with usual interstitial ...
Bronchial Disorders | Bronchiectasis | Bronchiolitis | MedlinePlus
Problems with the bronchi include bronchitis, bronchiectasis, and bronchiolitis. Learn more. ... Bronchiolitis Obliterans (National Jewish Health) * Flavorings-Related Lung Disease (National Institute for Occupational Safety ... Bronchiolitis (For Parents) (Nemours Foundation) Also in Spanish * Bronchiolitis: What Parents Should Know (American Academy of ... Bronchiolitis (American Academy of Family Physicians) Also in Spanish * Bronchiolitis (Mayo Foundation for Medical Education ...
Zithromax (azithromycin) dosing, indications, interactions, adverse effects, and more
Bronchiolitis obliterans. *August 3, 2018: FDA issues warning letter to healthcare providers ... Azithromycin is not indicated for prophylaxis of bronchiolitis obliterans syndrome (BOS) in patients undergoing HSCT and should ... evaluation of the efficacy of azithromycin to prevent bronchiolitis obliterans syndrome [BOS] after allogenic hematopoietic ...
bronchiolitis obliterans Archives - Breathe PA
by Marianne Drevna , Feb 15, 2017 , Education, Smoking Cessation, The Lungs. While it might seem like introducing unidentified "vapors" into your lungs via an electronic cigarette can in no way be healthy, there is still a lack of consistent evidence. There are more than 500 brands of e-cigarettes, making it difficult to gather data. However ...
Alarmins in bronchiolitis obliterans syndrome after lung transplantation - ePrints - Newcastle University
NIOSHTIC-2 Search Results - Full View
A case of unilateral bronchiolitis obliterans organizing pneumonia (BOOP). - Fingerprint - Creighton University
Browse Articles
| Bone Marrow Transplantation
Table of Contents - January 01, 2006, 27 (1) | European Respiratory Society
Nitrogen Oxides | Medical Management Guidelines | Toxic Substance Portal | ATSDR
If survived, this episode may be followed by bronchiolitis obliterans (fibrous obstruction of the bronchioles) several weeks ... The data on steroid use to prevent late sequelae (bronchiolitis obliterans) is anecdotal and somewhat controversial. ... of bronchiolitis obliterans by reducing inflammation and therefore lung damage. Steroids should be started soon after exposure ... bronchiolitis, emphysema, and possibly methemoglobinemia. Cough, hyperpnea, and dyspnea may be seen after some delay. ...
Hot Issues & Myths
Bronchiolitis Obliterans or "Popcorn Lung" - The Facts. The medical condition known as bronchiolitis obliterans (or the slang ... Some e-cigarette flavors contain diacetyl as an ingredient, and it is a possible cause of bronchiolitis obliterans. Popcorn ... Some common causes of bronchiolitis obliterans include inhaling chemicals such as chlorine, ammonia, sulfur dioxide, welding ... or Mycoplasma pneumonia have been linked with bronchiolitis obliterans as well. See a healthcare professional for a complete ...
COPD stages: Diagnosis and what to expect
"Bronchial hyperresponsiveness and the bronchiolitis obliterans syndrom" by David W. Reid, E Haydn Walters et al.
Because bronchial hyperresponsiveness has been linked to the bronchiolitis obliterans syndrome (BOS), we determined PD20 ... 2005). Bronchial hyperresponsiveness and the bronchiolitis obliterans syndrome after lung transplantation. Journal of Heart and ... Because bronchial hyperresponsiveness has been linked to the bronchiolitis obliterans syndrome (BOS), we determined PD20 ...
Status Asthmaticus Differential Diagnoses
Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT - Full Text View - ClinicalTrials.gov
Bronchiolitis Obliterans Organizing Pneumonia Cryptogenic Organizing Pneumonia Bronchiolitis Obliterans ... Bronchiolitis. Lung Diseases. Hypertension, Pulmonary. Pulmonary Arterial Hypertension. Pulmonary Fibrosis. Idiopathic ... Respiratory Bronchiolitis Associated ILD. Desquamative Interstitial Pneumonia. Cryptogenic Organizing Pneumonia. Acute ... Respiratory Bronchiolitis Associated Interstitial Lung Disease Desquamative Interstitial Pneumonia Cryptogenic Organizing ...
S-EPMC3582805 - Bronchoalveolar lavage as a tool to predict, diagnose and understand bronchiolitis obliterans syndrome. -...
Bronchiolitis obliterans syndrome (BOS), a condition of irreversible small airway fibrosis, is the principal factor limiting ... Survival after bronchiolitis obliterans syndrome among bilateral lung transplant recipients.. Project description:,h4,Rationale ... Project description:Bronchiolitis obliterans syndrome (BOS) is a condition of progressive airflow obstruction that affects a ... Project description:Bronchiolitis obliterans syndrome (BOS) may develop after either lung or haematopoietic stem cell ...
Bronchiolitis obliterans organizing pneumonia-like reactions: a nonspecific response or an atypical form of rejection or...
Bronchiolitis Obliterans Syndrome Pipeline Drugs and Companies Insight Report (2022): Analysis of Clinical Trials, Therapies,...
Bronchiolitis Obliterans Syndrome Therapeutic Assessment: Bronchiolitis Obliterans Syndrome current marketed and Bronchiolitis ... Bronchiolitis Obliterans Syndrome Market Dynamics: Bronchiolitis Obliterans Syndrome market drivers and Bronchiolitis ... Bronchiolitis Obliterans Syndrome Overview. Bronchiolitis Obliterans Syndrome (BOS) is a form of chronic lung allograft ... Bronchiolitis Obliterans Syndrome By Stage and Product Type. *Bronchiolitis Obliterans Syndrome Assessment by Route of ...
NIOSHTIC-2 Search Results - Full View
2. Symptoms of bronchiolitis obliterans are dry cough, shortness of breath, and wheezing. 3. Bronchiolitis obliterans is often ... What are the potential health effects of diacetyl? Lungs: The most commonly discussed lung disease is bronchiolitis obliterans ... life-threatening lung disease called bronchiolitis obliterans. 2. A recent article in the Seattle Post-Intelligencerl suggests ...
PneumoniaPopcorn lungDevelopment of bronchiolitis obliterans syndromeRisk of developing bronchiolitisCases of bronchiolitis obliteransObliterativePulmonary diseaseConstrictive bronchiolitisPost-infectious bronchiolitis obliteransTerm bronchiolitis obliteransInterstitialCase of bronchiolitisAcuteSmall airways2022RejectionLungsAirwaysPediatric bronchiolitisClinicalObstructive lung diRespiratoryIrreversible lung diseaseDisordersAsthmaBronchialDiacetyl exposureFindingsPatientsComplicationMeaslesSyndrome TreatmentCoughDiagnosisAllogeneicHematopoieticSymptomsSevereTreatmentRecipientsAffectsExposureRare
Pneumonia34
- When organizing pneumonia is associated with granulation tissue in the bronchiolar lumen, the qualifying term bronchiolitis obliterans (BO) is added. (medscape.com)
- Cryptogenic organizing pneumonia (COP) is often confused with bronchiolitis obliterans organizing pneumonia (BOOP). (medscape.com)
- Bronchiolitis obliterans organizing pneumonia is an inflammatory reaction with a variety of causes. (medscape.com)
- Transbronchial lung biopsy confirmed the diagnosis of bronchiolitis obliterans organizing pneumonia. (medscape.com)
- It is not related to cryptogenic organizing pneumonia, previously known as bronchiolitis obliterans organizing pneumonia. (wikipedia.org)
- Bronchiolitis obliterans and usual interstitial pneumonia. (uab.edu)
- The clinical, radiographic and pathologic features were studied in 24 cases of bronchiolitis obliterans and 16 cases of usual interstitial pneumonia, to define better their distinguishing characteristics. (uab.edu)
- Bronchiolitis obliterans had a more acute onset often associated with fever, while the presentation of usual interstitial pneumonia was insidious with dyspnea and cough. (uab.edu)
- The radiographs in usual interstitial pneumonia uniformly showed bilateral interstitial opacities, while they were more variable in bronchiolitis obliterans, with air space densities in 15 and interstitial opacities in nine. (uab.edu)
- The fibrosis in bronchiolitis obliterans was composed of proliferating fibroblasts, compared to collagen deposition in usual interstitial pneumonia. (uab.edu)
- These findings emphasize that bronchiolitis obliterans and usual interstitial pneumonia represent separate and distinct clinicopathologic entities. (uab.edu)
- A case of unilateral bronchiolitis obliterans organizing pneumonia (BOOP). (elsevier.com)
- Dive into the research topics of 'A case of unilateral bronchiolitis obliterans organizing pneumonia (BOOP). (elsevier.com)
- Respiratory infections caused by respiratory syncytial virus, adenovirus, or Mycoplasma pneumonia have been linked with bronchiolitis obliterans as well. (popcorn.org)
- Bronchiolitis obliterans organizing pneumonia-like reactions: a nonspecific response or an atypical form of rejection or infection in lung allograft recipients? (uchicago.edu)
- Bronchiolitis obliterans is a rare disease, so it is likely some workers in coffee roasting facilities have been misdiagnosed with asthma, bronchitis, emphysema or pneumonia in the past. (webwire.com)
- Lung disease and ulcerative colitis − mesalazine-induced bronchiolitis obliterans with organizing pneumonia or pulmonary manifestation of inflammatory bowel disease? (thieme-connect.de)
- Bronchiolitis obliterans organizing pneumonia in an AIDS patient. (doximity.com)
- Similar features were not observed in normal lung and in samples taken from other pulmonary diseases used as controls, including acute interstitial pneumonia, idiopathic bronchiolitis obliterans organizing pneumonia, nonspecific interstitial pneumonia, and desquamative interstitial pneumonia. (nih.gov)
- Bronchiolitis obliterans with organized pneumonia secondary to amiodarone: presentation of two cases with different therapeutic approach]. (pneumotox.com)
- Bronchiolitis obliterans organising pneumonia secondary to amiodarone treatment. (pneumotox.com)
- Bronchiolitis obliterans organizing pneumonia during low-dose amiodarone therapy. (pneumotox.com)
- Bronchiolitis obliterans organizing pneumonia secondary to amiodarone: clinical, radiological and histological pattern. (pneumotox.com)
- Bronchiolitis obliterans organizing pneumonia secondary to amiodarone: a rare aetiology. (pneumotox.com)
- Bronchiolitis obliterans organising pneumonia in patients taking acebutolol or amiodarone. (pneumotox.com)
- Organising pneumonia, previously called bronchiolitis obliterans organising pneumonia is a clinicopathological entity of unknown aetiology, which has been reported with increasing frequency. (bmj.com)
- This condition is not to be confused with BOOP (bronchiolitis obliterans organized pneumonia). (icd10monitor.com)
- Patients with RA may also develop bronchiolitis obliterans organizing pneumonia, an inflammation of the bronchioles with a comparatively good prognosis for recovery. (the-rheumatologist.org)
- The histopathologic features of idiopathic BOOP have several components: bronchiolitis obliterans, organizing pneumonia, accumulation of foamy cells in the peripheral air spaces, and interstitial infiltration of mononuclear cells. (1blu.de)
- Fatigue and low energy Because bronchiolitis obliterans affects breathing, you are likely to experienc… Bronchiolitis obliterans organising pneumonia (BOOP) is defined as organised polypoid granulation tissue in the distal airways extending into the alveolar ducts and alveoli. (1blu.de)
- Clinicopathologic study of various lung diseases with bronchiolitis obliterans organizing pneumonia (BOOP) pattern in open lung biopsy]. (1blu.de)
- Macrolides: A treatment alternative for bronchiolitis obliterans organizing pneumonia? (mskcc.org)
- 1] The most common primary causes of EN include streptococcal infections and other bacterial infections such as Yersinia enterocolitica, Mycoplasma pneumonia, Lymphogranuloma venereum (LGV), Salmonella and Campylobacter. (faoj.org)
- On her previous hospitalization, she was diagnosed with bronchiolitis obliterans organizing pneumonia (BOOP). (amjcaserep.com)
Popcorn lung19
- Bronchiolitis obliterans (BO), also known as obliterative bronchiolitis, constrictive bronchiolitis and popcorn lung, is a disease that results in obstruction of the smallest airways of the lungs (bronchioles) due to inflammation. (wikipedia.org)
- The medical condition known as bronchiolitis obliterans (or the slang term "popcorn lung") is an inflammatory condition that affects the lung's tiniest airways, the bronchioles. (popcorn.org)
- Breathing diacetyl is associated with the lung disease "Popcorn Lung," also known as bronchiolitis obliterans. (schmidtlaw.com)
- Popcorn lung, which is also known as bronchiolitis obliterans, is a rare disease that was first noticed among workers in a popcorn factory. (bleebot.com)
- More than a decade ago, diacetyl in microwave popcorn was linked to deaths and hundreds of cases of bronchiolitis obliterans, a serious and irreversible lung disease also known as "popcorn lung. (joyelawfirm.com)
- But, when inhaled in large amounts, can lead to 'Popcorn Lung' or bronchiolitis obliterans. (primaryhealth.org.au)
- Popcorn lung (bronchiolitis obliterans). (primaryhealth.org.au)
- Popcorn lung" is the nickname for bronchiolitis obliterans, a serious and irreversible lung disease that can damage the smallest airways in your lungs, resulting in coughing and shortness of breath. (jamaicahospital.org)
- Our vape juices are tailored to your needs and freshly made, steeping them is recommended.The scientific name for Popcorn Lung is bronchiolitis obliterans. (polandfashion.shop)
- Diacetyl could cause the illness known as popcorn lung or bronchiolitis obliterans. (ripevapes.com)
- The injury attorneys at DeBlasio & Gower are investigating devastating diacetyl exposure cases causing an injury known as bronchiolitis obliterans, sometimes called "popcorn lung. (dgllc.net)
- Bronchiolitis obliterans, which is sometimes referred to as " popcorn lung ", is one occupational disease that can have a range of health consequences. (hiladolaw.com)
- Bronchiolitis obliterans is called popcorn lung because of a chemical used during the packaging of microwave popcorn. (hiladolaw.com)
- Popcorn lung (bronchiolitis obliterans) is a rare kind of lung illness that is not associated with malignancy. (thecbdoilbenefits.com)
- The patient's clinical picture suggested possible bronchiolitis obliterans, or "popcorn lung," likely from inhaling flavoring agents in e-liquids. (cmajnews.com)
- This chemical is known to cause a very serious, irreversible, degenerative lung disease known as bronchiolitis obliterans or 'popcorn lung. (scottlawfirmtx.com)
- In the early 2000s, inhalation of diacetyl was found to be associated with bronchiolitis obliterans, also known as 'popcorn lung', when several popcorn-processing plant workers developed the condition. (haleonhealthpartner.com)
- When inhaled, diacetyl causes bronchiolitis obliterans - more commonly referred to as "popcorn lung" - a scarring of the tiny air sacs in the lungs resulting in the thickening and narrowing of the airways.27 мая 2020 г. (mindrightdetroit.com)
- The Occupational Safety and Health Administration and the flavoring industry have warned workers about diacetyl because of the association between inhaling the chemical and the debilitating respiratory disease bronchiolitis obliterans, colloquially known as "popcorn lung" because it first appeared in workers who inhaled artificial butter flavor in microwave popcorn processing facilities. (nkkhoo.com)
Development of bronchiolitis obliterans syndrome4
- Decreased percentage of CD4+FoxP3+ cells in bronchoalveolar lavage from lung transplant recipients correlates with development of bronchiolitis obliterans syndrome. (omicsdi.org)
- Unfortunately, lung transplant recipients have poor clinical outcomes, often due to the development of bronchiolitis obliterans syndrome (BOS). (omicsdi.org)
- Interleukin-6 and interferon-gamma gene polymorphisms in the development of bronchiolitis obliterans syndrome after lung transplantation. (cdc.gov)
- Early lung allograft dysfunction (ischemia-reperfusion injury) continues to be the most common cause of early mortality after lung transplantation and a significant risk factor for the development of bronchiolitis obliterans syndrome. (aai.org)
Risk of developing bronchiolitis2
- There has been an association shown between the increased use of peripheral stem cells and the risk of developing bronchiolitis obliterans. (wikipedia.org)
- But many other snack food companies are still exposing workers to diacetyl, leaving them at risk of developing bronchiolitis obliterans. (yourlawyer.com)
Cases of bronchiolitis obliterans1
- Brown University documented three cases of bronchiolitis obliterans (caused by diacetyl) in microwave popcorn lovers. (cookplatefork.com)
Obliterative7
- This process is often characterized by the pathologic findings of obliterative bronchiolitis: neutrophil influx and extracellular matrix remodeling leading to luminal obstruction and airway inflammation. (omicsdi.org)
- Pathologically, BOS presents as obliterative bronchiolitis (OB) and it is characterized by peribronchial inflammation, epithelial damage, and obliteration of small and medium-sized bronchioli by fibrotic plaques. (helsinki.fi)
- Several tests are often needed to diagnose obliterative bronchiolitis, including spirometry, diffusing capacity of the lung tests (DLCO), lung volume tests, chest X-rays, high-resolution CT (HRCT), and lung biopsy. (1blu.de)
- Obliterative bronchiolitis is a type of obstructive lung disease of the small airways 2). (1blu.de)
- Bronchiolitis obliterans also known as obliterative bronchiolitis, is a manifestation of chronic allograft rejection, that is, rejection following lung transplantation from another human being. (1blu.de)
- as bronchiolitis obliterans syndrome (BOS), which is thought to be caused by inflammation, destruction and fibrosis of small airways in the lung allograft that leads to obliterative bronchiolitis (OB). (1blu.de)
- Its real name is bronchiolitis obliterans, or obliterative bronchiolitis. (rossgastronomica.com)
Pulmonary disease2
- The small airways of the human lung undergo pathological changes in pulmonary disorders, such as chronic obstructive pulmonary disease (COPD), asthma, bronchiolitis obliterans and cystic fibrosis. (duke.edu)
- gastrointestinal such as cirrhosis, celiac disease, inflammatory bowel disease infectious disease such as HIV, tuberculosis, hepatitis pulmonary disease such as bronchiolitis obliterans, small cell lung cancer lymphoma dermatitis herpetiformis seronegative arthritis. (coem.com)
Constrictive bronchiolitis2
- Thus, e.g., inhibition of metabolic changes including air trapping, bronchial wall thickening, and clearance pathways leads to a diminished scrubbing capacity constrictive bronchiolitis (Akpinar-Elci et al. (cdc.gov)
- We review current concepts about the clinical manifestations, diagnosis and treatment of patients with bronchiolitis obliterans (BO) with emphasis on clinical/pathological correlations and … Bronchiolitis obliterans (BO) is also known as constrictive bronchiolitis. (1blu.de)
Post-infectious bronchiolitis obliterans1
- Post infectious bronchiolitis obliterans is long term damage to the small breathing tubes after an infection. (1blu.de)
Term bronchiolitis obliterans3
- Prior descriptions occurred as early as 1956, with the term "bronchiolitis obliterans" used first by Reynaud in 1835. (wikipedia.org)
- The term "bronchiolitis obliterans" was historically used by pathologists to refer to two distinct patterns of small-airway disease. (1blu.de)
- The term Bronchiolitis obliterans is occasionally used to refer to a particularly severe type of pediatric bronchiolitis that is caused by adenovirus. (1blu.de)
Interstitial3
- Pathologically, the lesion in bronchiolitis obliterans affected mainly air spaces in a peribronchiolar distribution, while the changes in usual interstitial penumonia were mainly interstitial and randomly distributed. (uab.edu)
- Rarely, there has also been evidence of interstitial lung disease, such as sarcoidosis, pulmonary fibrosis, and bronchiolitis obliterans. (cdc.gov)
- Patients can develop interstitial lung disease or bronchiolitis obliterans after an episode of nitrogen dioxide poisoning. (logicalimages.com)
Case of bronchiolitis1
- â which publicized the first reported case of bronchiolitis obliterans in a consumer and the pathetic reaction from public health agencies. (thepumphandle.org)
Acute6
- Among lung transplant recipients, tacrolimus compared to cyclosporine may be associated with decreased incidence of bronchiolitis obliterans syndrome and number of acute rejection episodes. (empr.com)
- Erythema nodosum (EN) is an acute, nodular, erythematous eruption primarily isolated to the lower legs. (faoj.org)
- In the eruptive phase of EN, malaise and fever are accompanied by acute nodular pain to the legs. (faoj.org)
- Why the patient developed acute groin adenopathy before EN is still in question. (faoj.org)
- For many years, the primary CLAD phenotype was recognized as bronchiolitis obliterans syndrome (BOS), characterized by an isolated decline in FEV1 consistent with obstructive physiology, without an identifiable cause such as acute rejection or infection. (fsmr.org)
- After exclusion of samples obtained during pulmonary rejection, bronchiolitis obliterans or acute bacterial infection, 48 blood and BAL samples were retained for analysis: 17 were CMV positive by shell-vial assay and 31 were CMV negative in blood and BAL. (shengsci.com)
Small airways5
- Bronchiolitis obliterans occurs when small airways become inflamed and scarred. (webwire.com)
- The histologic manifestation of chronic rejection is bronchiolitis obliterans ( 1 , 2 ), a rapidly progressive inflammatory disorder of the small airways of the transplanted lung causing severe obstructive lung disease, mostly irreversible and unresponsive to therapy ( 1 ). (snmjournals.org)
- But in Canada, doctors in the CMAJ study determined the lungs of the young vaper suffered from bronchiolitis obliterans, which is inflammation of the small airways off the lungs called bronchioles. (inquirer.net)
- Bronchiolitis targets small airways inside the lungs, scars them, and impairs their function. (vaperoyalty.com)
- The inhalation of flavoring concentrate may expose you to hazardous chemicals, toxins, and nanoparticles, including diacetyl, acetyl propionyl and/or acetoin, which have been associated with permanent lung injury and disease, including bronchiolitis obliterans, a disease characterized by inflammation and scarring of the small airways of the lungs, which leads to severe and disabling shortness of breath. (flavorah.com)
20221
- " Bronchiolitis Obliterans Syndrome Pipeline Insight, 2022 " report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Bronchiolitis Obliterans Syndrome Market. (itanagarnews.in)
Rejection5
- Alloimmune responses play an important role in progression to chronic rejection that manifests as bronchiolitis obliterans syndrome (BOS), but no biomarker can currently predict the progression to BOS. (omicsdi.org)
- Rejection and, specifically, bronchiolitis obliterans (BO) remains a major hurdle to overcome. (medscape.com)
- Increasing age was associated with decreases in early post-operative infections, reduction in the cumulative hazard of developing bronchiolitis obliterans (BO) syndrome, and decreases in hospitalizations and treatment for rejection. (elsevier.com)
- This report describes the epidemiology of CDC in lung recipients from a single center and explores possible associations with bronchiolitis obliterans syndrome (BOS), a surrogate marker of chronic rejection. (utmb.edu)
- Particularly susceptible are lung transplant recipients, in whom influenza may induce organ rejection and bronchiolitis obliterans syndrome (1, 7-10). (mdatl.com)
Lungs5
- Bronchiolitis obliterans is a common complication in lung transplants because transplanted lungs are at greater risk of alloimmunization as compared to healthy lungs. (wikipedia.org)
- Lungs: The most commonly discussed lung disease is bronchiolitis obliterans. (cdc.gov)
- Bronchiolitis obliterans causes scarring of the tiny air sacs in the lungs resulting in the thickening and narrowing of the airways, according to the American Lung Association . (joyelawfirm.com)
- If that's not bad enough there is also very concerning information about diacetyl which is a chemical in the butter flavoring of most microwave popcorn brands and has been associated with a lung disease called bronchiolitis obliterans which causes pulmonary inflammation and obstruction of the lungs. (conceivingconcepts.com)
- This chemical can increase the risk of bronchiolitis obliterans, a lung condition that causes breathing difficulties and scarring of the airways in the lungs. (medical-news.org)
Airways2
- An innovative development by CannaMore of a CBD based solution for treatments of Bronchiolitis obliterans (BOS), a pulmonary inflammatory disease characterized obstruction of the lung's tiniest airways, called bronchioles. (cannamorebio.com)
- Bronchiolitis obliterans is a rare condition that causes inflammation in the airways, leading to scarring and permanent damage. (primaryhealth.org.au)
Pediatric bronchiolitis1
- Long-term pulmonary function testing in pediatric bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation. (stembook.org)
Clinical5
- Positive Phase Ib clinical trial results for L-CsA, inhaled liposomal cyclosporine A for the prevention and treatment of bronchiolitis obliterans from PARI Pharma , Monterey, Calif, are reported in the Journal of Aerosol Medicine and Pulmonary Drug Delivery . (rtmagazine.com)
- Bronchiolitis Obliterans Syndrome pipeline constitutes 5+ key companies continuously working towards developing 10+ Bronchiolitis Obliterans Syndrome treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight. (itanagarnews.in)
- The Bronchiolitis Obliterans Syndrome Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. (itanagarnews.in)
- Currently based on several clinical findings Bronchiolitis obliterans (BO) was confirmed as the major diagnosis in these sufferers. (sid.ir)
- Moreover, clinical bronchiolitis obliterans also min. (cdc.gov)
Obstructive lung di1
- Bronchiolitis obliterans is an obstructive lung disease triggered by a bronchiolar injury, which leads to inflammatory fibrosis and narrowing of the distal bronchioles. (lecturio.com)
Respiratory2
- This has the potential to prevent and treat bronchiolitis obliterans in a more efficient way compared to current oral standard treatment," said Jürgen Behr, MD, head of the Division of Respiratory Disease at the Ludwig Maximilians University, Munich, Germany, in a press announcement from PARI. (rtmagazine.com)
- While bronchiolitis is manageable, it can also be life-threatening in rare cases, such as when it causes respiratory failure. (1blu.de)
Irreversible lung disease1
- The medical term is bronchiolitis obliterans, and it's an irreversible lung disease. (garthsbrewbar.com)
Disorders1
- Clenbuterol (Cutting) The steroid Clenbuterol is used for the treatment of breathing disorders such as asthma, COPD, allergies, and bronchiolitis obliterans. (atomysynergy.com)
Asthma3
- 3. Bronchiolitis obliterans is often mistaken for other lung diseases, such as asthma. (cdc.gov)
- Late Pre-term Infants With Severe Bronchiolitis and Risk of Asthma by Age 5 Years. (amedeo.com)
- Clenbuterol has the following additional functions: Improves the control of breathing problems in people with asthma Helps relieve symptoms such as cough Reduces or eliminates difficulty in breathing Treats allergic rhinitis Treats bronchiolitis obliterans Clenbuterol (Cough) Cutaneous Clenbuterol is a product used for the treatment of cough, wheezing and colds. (atomysynergy.com)
Bronchial2
- Bronchial hyperresponsiveness and the bronchiolitis obliterans syndrom" by David W. Reid, E Haydn Walters et al. (edu.au)
- Because bronchial hyperresponsiveness has been linked to the bronchiolitis obliterans syndrome (BOS), we determined PD 20 methacholine (PD 20(M) ), PD 15 hypertonic saline (PD 15(HS) ) and their dose-response slopes (DRS M and DRS HS ) in 8 single and 18 double lung transplant recipients within 1 year of lung transplantation and examined the relationship to bronchoalveolar lavage cell profiles and subsequent development of BOS. (edu.au)
Diacetyl exposure1
- But despite all the evidence linking diacetyl exposure to the onset of bronchiolitis obliterans, no agency of the federal government has sought to regulate the toxic substance. (yourlawyer.com)
Findings1
- The survey findings are best explained by work-related bronchiolitis obliterans due to exposures arising from the open configuration of the mixing tanks which allowed volatile organic compounds (VOCs) to be disseminated to other areas of the plant, as well as due to the quality control process where many bags of microwave popcorn were popped in a small room with minimal general dilution ventilation. (cdc.gov)
Patients3
- Prognosis was considerably better for bronchiolitis obliterans patients. (uab.edu)
- Mallinckrodt plc (NYSE: MNK), a leading specialty pharmaceutical company, announced that Switzerland's Federal Department of Home Affairs (FDHA) has approved reimbursement of Extracorporeal Photopheresis (ECP) treatment for patients in Switzerland with Bronchiolitis Obliterans Syndrome (BOS) following lung transplantation. (mallinckrodt.com)
- Bronchiolitis obliterans syndrome, or BOS, is a rare but deadly complication of blood stem cell transplant that impacts about 5 percent of the 9,000 patients who undergo allogenic bone marrow transplant each year. (fredhutch.org)
Complication2
- Bronchiolitis obliterans is also associated with rheumatic disease and is an important complication to recognize following a lung or hematopoietic stem-cell transplant. (lecturio.com)
- Bronchiolitis obliterans syndrome (BOS) is a major complication of lung transplantation that is associated with poor survival. (1blu.de)
Measles2
Syndrome Treatment3
- Companies across the globe are diligently working toward developing novel Bronchiolitis Obliterans Syndrome treatment therapies with a considerable amount of success over the years. (itanagarnews.in)
- The report provides detailed insights about companies that are developing therapies for the Bronchiolitis Obliterans Syndrome treatment with aggregate therapies developed by each company for the same. (itanagarnews.in)
- It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Bronchiolitis Obliterans Syndrome Treatment. (itanagarnews.in)
Cough2
- Bronchiolitis obliterans results in worsening shortness of breath, wheezing, and a dry cough. (wikipedia.org)
- 2. Symptoms of bronchiolitis obliterans are dry cough, shortness of breath, and wheezing. (cdc.gov)
Diagnosis2
- The diagnosis of bronchiolitis obliterans lung begins by taking a thorough history, and additional testing is required to confirm the diagnosis. (1blu.de)
- The diagnosis and management of bronchiolitis obliterans is done with a multidisciplinary team that includes a transplant surgeon, pulmonologist, pathologist, radiologist, internist, nurse practitioner, and a pharmacist. (1blu.de)
Allogeneic1
- Morbidity and mortality from bronchiolitis obliterans syndrome (BOS) remain unacceptably high after allogeneic hematopoietic cell transplantation (A-HCT) (1). (monitoredrx.com)
Hematopoietic1
- The disease is often termed bronchiolitis obliterans syndrome (BOS) in the setting of post lung transplantation and hematopoietic stem cell transplant (HSCT). (wikipedia.org)
Symptoms3
- This will help confirm whether they have the symptoms of bronchiolitis. (1blu.de)
- The most common symptoms of bronchiolitis obliterans are:1 1. (1blu.de)
- After workers at the factories that produced microwave popcorn began to experience symptoms associated with bronchiolitis obliterans after inhaling diacetyl, manufacturers removed it from their products. (jamaicahospital.org)
Severe2
- 1. In microwave popcorn production and the manufacture of food flavorings, airborne exposures to food flavorings containing diacetyl have been linked to a severe, life-threatening lung disease called bronchiolitis obliterans. (cdc.gov)
- The loss of pulmonary function associated with severe bronchiolitis obliterans is permanent, so preventing the disease is essential. (webwire.com)
Treatment2
- Paraneoplastic pemphigus associated with fatal bronchiolitis obliterans and intractable mucosal erosions: Treatment with cyclosporinin addition to steroid, rituximab immunoglobulin. (thefreedictionary.com)
- O'Hagan AR, Stillwell PC, Arroliga A, Koo A. Photopheresis in the treatment of refractory bronchiolitis obliterans complicating lung transplantation. (ucdenver.edu)
Recipients1
- Bronchiolitis Obliterans Syndrome (BOS) is a form of chronic lung allograft dysfunction that affects a majority of lung transplant recipients and is the principal factor limiting long-term transplant survival. (itanagarnews.in)
Affects1
- Bronchiolitis obliterans affects up to 5.5% of people who have received HSCT. (wikipedia.org)
Exposure1
- Bronchiolitis obliterans from exposure to incinerator fly ash. (doximity.com)
Rare3
- Bronchiolitis obliterans is rare in the general population. (wikipedia.org)
- Bronchiolitis obliterans rare usually late in pregnancy or an intimidating instructor. (wisc.edu)
- There are also reports that the flavoring chemicals in the liquid, diacetyl and acetyl propionyl, are extremely harmful when vaporized and can result in bronchiolitis obliterans, a rare and fatal lung condition. (tatelawgroup.com)