Persistent abnormal dilatation of the bronchi.
Radiography of the bronchial tree after injection of a contrast medium.
Material coughed up from the lungs and expectorated via the mouth. It contains MUCUS, cellular debris, and microorganisms. It may also contain blood or pus.
Conditions caused by abnormal CILIA movement in the body, usually causing KARTAGENER SYNDROME, chronic respiratory disorders, chronic SINUSITIS, and chronic OTITIS. Abnormal ciliary beating is likely due to defects in any of the 200 plus ciliary proteins, such as missing motor enzyme DYNEIN arms.
Hypersensitivity reaction (ALLERGIC REACTION) to fungus ASPERGILLUS in an individual with long-standing BRONCHIAL ASTHMA. It is characterized by pulmonary infiltrates, EOSINOPHILIA, elevated serum IMMUNOGLOBULIN E, and skin reactivity to Aspergillus antigen.
Expectoration or spitting of blood originating from any part of the RESPIRATORY TRACT, usually from hemorrhage in the lung parenchyma (PULMONARY ALVEOLI) and the BRONCHIAL ARTERIES.
A non-specific host defense mechanism that removes MUCUS and other material from the LUNGS by ciliary and secretory activity of the tracheobronchial submucosal glands. It is measured in vivo as mucus transfer, ciliary beat frequency, and clearance of radioactive tracers.
An autosomal recessive disorder characterized by a triad of DEXTROCARDIA; INFERTILITY; and SINUSITIS. The syndrome is caused by mutations of DYNEIN genes encoding motility proteins which are components of sperm tails, and CILIA in the respiratory and the reproductive tracts.
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.
Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.
A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI.
The volume of air that is exhaled by a maximal expiration following a maximal inspiration.
The viscous secretion of mucous membranes. It contains mucin, white blood cells, water, inorganic salts, and exfoliated cells.
Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.
A pathologic process consisting in the formation of pus.
Infections with bacteria of the genus PSEUDOMONAS.
Pathological processes involving any part of the LUNG.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.

A pilot study of low-dose erythromycin in bronchiectasis. (1/518)

Patients with bronchiectasis suffer from sputum production, recurrent exacerbations, and progressive airway destruction. Erythromycin is effective in diffuse panbronchiolitis, another suppurative airway disorder, although its efficacy is unknown in idiopathic bronchiectasis. A double-blind placebo-controlled study was therefore conducted to evaluate the effects of 8-week administration of low dose erythromycin (500 mg b.i.d.) in steady-state idiopathic bronchiectasis. Patients in the erythromycin group (n=11, 8 female, mean age 50+/-15 yrs), but not the placebo group (n=10, 8 female, mean age 59+/-16 yrs) had significantly improved forced expiratory volume in one second, forced vital capacity and 24-h sputum volume after 8 weeks (p<0.05). There was no parallel improvement in sputum pathogens, leukocytes, interleukin (IL)-1alpha and IL-8, tumour necrosis factor-alpha, or leukotriene B4. The results of this pilot study show that low-dose erythromycin improves lung function and sputum volume in bronchiectasis. Further studies are indicated to evaluate the efficacy of long-term erythromycin therapy in bronchiectasis.  (+info)

Degradation of porstaglandin F2alpha in the human pulmonary circulation. (2/518)

Degradation of prostaglandins (PGs) during passage through the human pulmonary circulation was investigated by measuring the transpulmonary plasma PGF2 alpha difference during continuous intravenous infusion of PGF2 alpha (5-10 mug/min). Seven patients with cardiological disorders and two patients with extensive pulmonary abnormalities were investigated during diagnostic cardiac catheterization. PGF2 alpha levels were measured by radioimmunoassay. The seven cardiac patients were found to have transpulmonary PGF2 alpha differences of 47-88%, indicating metabolism of the PG in the lungs. A patient with extensive bronchiectasis had an apparently normal transpulmonary PGF2alpha difference despite gross abnormalities in routine lung function tests. A patient with primary pulmonary arterial hypertension showed no metabolism of PGF2alpha in the pulmonary circulation. The results show that PG degradation is an aspect of normal lung function and suggest that it becomes imparied when extensive pulmonary vascular damage exists.  (+info)

Increased levels of exhaled carbon monoxide in bronchiectasis: a new marker of oxidative stress. (3/518)

BACKGROUND: Bronchiectasis is a chronic inflammatory lung disease associated with increased production of oxidants due mostly to neutrophilic inflammation. Induction of heme oxygenase (HO-1) by reactive oxygen species is a general cytoprotective mechanism against oxidative stress. HO-1 catabolises heme to bilirubin, free iron and carbon monoxide (CO). Exhaled CO measurements may therefore reflect an oxidative stress and be clinically useful in the detection and management of inflammatory lung disorders. METHODS: The levels of exhaled CO of 42 non-smoking patients with bronchiectasis treated or not treated with inhaled corticosteroids were compared with CO levels in 37 normal non-smoking subjects. RESULTS: Levels of exhaled CO were raised in patients with bronchiectasis, both those treated with inhaled corticosteroids (n = 27, median 5.5 ppm, 95% CI 5.16 to 7.76) and those not treated with inhaled corticosteroids (n = 15, median 6.0 ppm. 95% CI 4.74 to 11.8), compared with normal subjects (n = 37, median 3.0 ppm, 95% CI 2.79 to 3.81, p = 0.0024). There was no correlation between exhaled CO and HbCO levels (r = 0.42, p = 0.12) in normal subjects (n = 7), nor between the urine cotinine concentration and exhaled CO levels (r = 0.2, p = 0.12). CONCLUSIONS: Increased levels of exhaled CO may reflect induction of HO-1 and oxidative stress in bronchiectasis. Measurement of exhaled CO may be useful in the management of bronchiectasis and possibly other chronic inflammatory lung disorders.  (+info)

Pseudomonas aeruginosa hemolytic phospholipase C suppresses neutrophil respiratory burst activity. (4/518)

Pseudomonas aeruginosa is a persistent pathogen in the airways of patients with cystic fibrosis or bronchiectasis from other causes and appears to have evolved strategies to survive the inflammatory response of the host. We hypothesized that the secreted hemolytic phospholipase C (PLC) of P. aeruginosa (PlcHR) would decrease neutrophil respiratory burst activity. We found that while intact wild-type P. aeruginosa cells stimulated moderate respiratory burst activity from human neutrophils, an isogenic mutant pseudomonas (DeltaHR strain) containing a targeted deletion of the plcHR operon induced a much more robust oxidative burst from neutrophils. In contrast, a second pseudomonas mutant (DeltaN) containing a disruption in the gene encoding the nonhemolytic PLC (PlcN) was not different from the wild type in stimulating neutrophil O2.- production. Readdition of purified PlcHR to the DeltaHR strain suppressed neutrophil O2.- production to levels stimulated by wild-type bacteria. Interestingly, purified PlcHR decreased phorbol myristate acetate (PMA)- but not formyl methionyl-leucyl-proline (fMLP)-induced respiratory burst activity, suggesting interference by PlcHR with a protein kinase C (PKC)-specific signaling pathway. Accordingly, the PKC inhibitor bisindolylmaleimide inhibited the oxidative burst induced by either PMA or intact pseudomonas, but not by fMLP, whereas the p38 kinase inhibitor SB-203580 fully inhibited the respiratory burst induced by fMLP or the PlcHR-replete wild-type bacteria, but not PMA or the PlcHR-deficient DeltaHR bacterial mutant. We conclude that expression of PlcHR by P. aeruginosa suppresses bacterium-induced neutrophil respiratory burst by interfering with a PKC-dependent, non-p38 kinase-dependent pathway.  (+info)

A resuscitated case from asphyxia by large bronchial cast. (5/518)

A 62-year-old woman with bronchiectasis suffered from asphyxia due to a large bronchial cast that obstructed the bronchial tree. Immediate bronchoscopic suction of a bronchial cast of 17 cm in length through the intubated tube relieved the patients without any complications. Large bronchial casts appear to be rare in this century but it should be considered in patients with acute exacerbation of excessive sputa not only in patients with asthma or allergy but also in patients with respiratory tract infection.  (+info)

Epidemiological analysis of sequential Pseudomonas aeruginosa isolates from chronic bronchiectasis patients without cystic fibrosis. (6/518)

PCR fingerprinting was used for the epidemiological investigation of 64 Pseudomonas aeruginosa isolates collected from 16 chronic bronchiectasis patients without cystic fibrosis: 56% of the patients harbored one clone, 12.5% carried a single major type with minor variants, and 31.5% carried two clones. Only a minority of the acquisitions of antibiotic resistance was related to the acquisition of exogenous strains. Mucoid and nonmucoid sets of isolates did not display any consistent differences in their patterns. The genetic similarity among the clones ranged from 10 to 69%. Cross-infection or common-source exposure did not appear to have occurred.  (+info)

A possible mechanism of primary ciliary dyskinesia: a case of a segmental defect in ciliary microtubules. (7/518)

We report here a 13-year-old woman with cough, sputum and fever. The patient had both chronic sinusitis and bronchitis. Chest X-ray and computed tomographic scan of the chest revealed mucous bronchial filling and bronchiectasia in bronchi of bilateral lower lobes, right middle lobe and left upper lobe. Aerosol inhalation scintigraphy with 99mTechnetium demonstrated delays of the discharged tracer. On the basis of these findings, primary ciliary dyskinesia was suggested. This was confirmed by the findings from nasal biopsy with transmission electron microscopy where all of the microtubules were segmentally defected near the basal body in the cilia. On the basis of these findings, we diagnosed the patient with primary ciliary dyskinesia which may be due, at least in part, to segmental defect of ciliary microtubules.  (+info)

Respiratory epithelial ion transport in patients with disseminated bronchiectasis. (8/518)

The nosological limits between disseminated bronchiectasis and cystic fibrosis (CF) remain unclear. In patients with isolated congenital bilateral absence of the vas deferens, a forme fruste of the CF disease, a normal baseline nasal transepithelial potential difference (PD) but an impaired response to pharmacological interventions have been reported. The purpose of the present study was to explore ion transport in respiratory epithelium from patients with disseminated bronchiectasis. The PD under both baseline and pharmacological interventions was investigated in 13 healthy subjects, six patients with genetically proven CF and 15 patients with disseminated bronchiectasis as confirmed by computed tomography scan. Baseline PD was similar in the control and bronchiectasis groups but, as expected, was significantly more negative in the CF group. Patients with bronchiectasis responded to pharmacological tests (sequential perfusion with amiloride, chloride-free solution, isoprenaline and uridine triphosphate (UTP) similarly to healthy subjects. In contrast, CF patients exhibited an increased response to amiloride and an impaired response to chloride-free solution and isoprenaline. The data show that patients with disseminated bronchiectasis exhibit normal electrophysiological properties in their nasal epithelium. Nasal transepithelial potential difference including pharmacological tests may appear a valuable diagnostic procedure for cystic fibrosis with disseminated bronchiectasis.  (+info)

Bronchiectasis is a medical condition characterized by permanent, abnormal widening and thickening of the walls of the bronchi (the airways leading to the lungs). This can lead to recurrent respiratory infections, coughing, and the production of large amounts of sputum. The damage to the airways is usually irreversible and can be caused by various factors such as bacterial or viral infections, genetic disorders, immune deficiencies, or exposure to environmental pollutants. In some cases, the cause may remain unknown. Treatment typically includes chest physiotherapy, bronchodilators, antibiotics, and sometimes surgery.

Bronchography is a medical imaging technique that involves the injection of a contrast material into the airways (bronchi) of the lungs, followed by X-ray imaging to produce detailed pictures of the bronchial tree. This diagnostic procedure was commonly used in the past to identify abnormalities such as narrowing, blockages, or inflammation in the airways, but it has largely been replaced by newer, less invasive techniques like computed tomography (CT) scans and bronchoscopy.

The process of bronchography involves the following steps:

1. The patient is sedated or given a local anesthetic to minimize discomfort during the procedure.
2. A radiopaque contrast material is introduced into the bronchi through a catheter that is inserted into the trachea, either via a nostril or through a small incision in the neck.
3. Once the contrast material has been distributed throughout the bronchial tree, X-ray images are taken from various angles to capture detailed views of the airways.
4. The images are then analyzed by a radiologist to identify any abnormalities or irregularities in the structure and function of the bronchi.

Although bronchography is considered a relatively safe procedure, it does carry some risks, including allergic reactions to the contrast material, infection, and bleeding. Additionally, the use of ionizing radiation during X-ray imaging should be carefully weighed against the potential benefits of the procedure.

Sputum is defined as a mixture of saliva and phlegm that is expelled from the respiratory tract during coughing, sneezing or deep breathing. It can be clear, mucoid, or purulent (containing pus) depending on the underlying cause of the respiratory issue. Examination of sputum can help diagnose various respiratory conditions such as infections, inflammation, or other lung diseases.

Ciliary motility disorders are a group of rare genetic conditions that affect the function of cilia, which are tiny hair-like structures on the surface of cells in the body. Cilia play an important role in moving fluids and particles across the cell surface, including the movement of mucus and other substances in the respiratory system, the movement of eggs and sperm in the reproductive system, and the movement of fluid in the inner ear.

Ciliary motility disorders are caused by mutations in genes that are responsible for the proper functioning of cilia. These mutations can lead to abnormalities in the structure or function of cilia, which can result in a range of symptoms depending on the specific disorder and the parts of the body that are affected.

Some common symptoms of ciliary motility disorders include recurrent respiratory infections, chronic sinusitis, hearing loss, infertility, and situs inversus, a condition in which the major organs are reversed or mirrored from their normal positions. There are several different types of ciliary motility disorders, including primary ciliary dyskinesia, Kartagener syndrome, and immotile cilia syndrome.

Treatment for ciliary motility disorders typically involves addressing the specific symptoms and underlying causes of the disorder. This may include antibiotics to treat respiratory infections, surgery to correct structural abnormalities, or assisted reproductive technologies to help with infertility.

Allergic bronchopulmonary aspergillosis (ABPA) is a medical condition characterized by an hypersensitivity reaction to the fungus Aspergillus species, most commonly A. fumigatus. It primarily affects the airways and lung tissue. The immune system overreacts to the presence of the fungus, leading to inflammation and damage in the lungs.

The main symptoms of ABPA include wheezing, coughing, production of thick mucus, shortness of breath, and chest tightness. These symptoms are similar to those seen in asthma and other respiratory conditions. Some people with ABPA may also experience fever, weight loss, and fatigue.

Diagnosis of ABPA typically involves a combination of clinical evaluation, imaging studies (such as chest X-rays or CT scans), and laboratory tests (such as blood tests or sputum cultures) to detect the presence of Aspergillus species and elevated levels of certain antibodies.

Treatment for ABPA usually involves a combination of corticosteroids to reduce inflammation and antifungal medications to eradicate the Aspergillus infection. In some cases, immunomodulatory therapies may also be used to help regulate the immune system's response to the fungus.

It is important to note that ABPA can lead to serious complications if left untreated, including bronchiectasis (permanent enlargement of the airways), pulmonary fibrosis (scarring of the lung tissue), and respiratory failure. Therefore, prompt diagnosis and treatment are essential for managing this condition.

Hemoptysis is the medical term for coughing up blood that originates from the lungs or lower respiratory tract. It can range in severity from streaks of blood mixed with mucus to large amounts of pure blood. Hemoptysis may be a sign of various underlying conditions, such as bronchitis, pneumonia, tuberculosis, cancer, or blood disorders. Immediate medical attention is required when hemoptysis occurs, especially if it's in significant quantities, to determine the cause and provide appropriate treatment.

Mucociliary clearance is a vital defense mechanism of the respiratory system that involves the coordinated movement of tiny hair-like structures called cilia, which are present on the surface of the respiratory epithelium, and the mucus layer. This mechanism helps to trap inhaled particles, microorganisms, and other harmful substances and move them away from the lungs towards the upper airways, where they can be swallowed or coughed out.

The cilia beat in a coordinated manner, moving in a wave-like motion to propel the mucus layer upwards. This continuous movement helps to clear the airways of any debris and maintain a clean and healthy respiratory system. Mucociliary clearance plays an essential role in preventing respiratory infections and maintaining lung function. Any impairment in this mechanism, such as due to smoking or certain respiratory conditions, can increase the risk of respiratory infections and other related health issues.

Kartagener Syndrome is a rare genetic disorder that primarily affects the respiratory system. It is characterized by the triad of chronic sinusitis, bronchiectasis (damage and widening of the airways in the lungs), and situs inversus totalis - a condition where the major visceral organs are mirrored or reversed from their normal positions.

In Kartagener Syndrome, the cilia (tiny hair-like structures) lining the respiratory tract are abnormal or dysfunctional, which impairs their ability to clear mucus and other particles. This leads to recurrent respiratory infections, bronchiectasis, and ultimately, progressive lung damage.

The condition is inherited as an autosomal recessive trait, meaning that an individual must inherit two copies of the defective gene - one from each parent - to develop the syndrome. Kartagener Syndrome is a subtype of primary ciliary dyskinesia (PCD), a group of disorders affecting ciliary structure and function.

Cystic fibrosis (CF) is a genetic disorder that primarily affects the lungs and digestive system. It is caused by mutations in the CFTR gene, which regulates the movement of salt and water in and out of cells. When this gene is not functioning properly, thick, sticky mucus builds up in various organs, leading to a range of symptoms.

In the lungs, this mucus can clog the airways, making it difficult to breathe and increasing the risk of lung infections. Over time, lung damage can occur, which may lead to respiratory failure. In the digestive system, the thick mucus can prevent the release of digestive enzymes from the pancreas, impairing nutrient absorption and leading to malnutrition. CF can also affect the reproductive system, liver, and other organs.

Symptoms of cystic fibrosis may include persistent coughing, wheezing, lung infections, difficulty gaining weight, greasy stools, and frequent greasy diarrhea. The severity of the disease can vary significantly among individuals, depending on the specific genetic mutations they have inherited.

Currently, there is no cure for cystic fibrosis, but treatments are available to help manage symptoms and slow the progression of the disease. These may include airway clearance techniques, medications to thin mucus, antibiotics to treat infections, enzyme replacement therapy, and a high-calorie, high-fat diet. Lung transplantation is an option for some individuals with advanced lung disease.

X-ray computed tomography (CT or CAT scan) is a medical imaging method that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of the body. These cross-sectional images can then be used to display detailed internal views of organs, bones, and soft tissues in the body.

The term "computed tomography" is used instead of "CT scan" or "CAT scan" because the machines take a series of X-ray measurements from different angles around the body and then use a computer to process these data to create detailed images of internal structures within the body.

CT scanning is a noninvasive, painless medical test that helps physicians diagnose and treat medical conditions. CT imaging provides detailed information about many types of tissue including lung, bone, soft tissue and blood vessels. CT examinations can be performed on every part of the body for a variety of reasons including diagnosis, surgical planning, and monitoring of therapeutic responses.

In computed tomography (CT), an X-ray source and detector rotate around the patient, measuring the X-ray attenuation at many different angles. A computer uses this data to construct a cross-sectional image by the process of reconstruction. This technique is called "tomography". The term "computed" refers to the use of a computer to reconstruct the images.

CT has become an important tool in medical imaging and diagnosis, allowing radiologists and other physicians to view detailed internal images of the body. It can help identify many different medical conditions including cancer, heart disease, lung nodules, liver tumors, and internal injuries from trauma. CT is also commonly used for guiding biopsies and other minimally invasive procedures.

In summary, X-ray computed tomography (CT or CAT scan) is a medical imaging technique that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional images of the body. It provides detailed internal views of organs, bones, and soft tissues in the body, allowing physicians to diagnose and treat medical conditions.

Respiratory Function Tests (RFTs) are a group of medical tests that measure how well your lungs take in and exhale air, and how well they transfer oxygen and carbon dioxide into and out of your blood. They can help diagnose certain lung disorders, measure the severity of lung disease, and monitor response to treatment.

RFTs include several types of tests, such as:

1. Spirometry: This test measures how much air you can exhale and how quickly you can do it. It's often used to diagnose and monitor conditions like asthma, chronic obstructive pulmonary disease (COPD), and other lung diseases.
2. Lung volume testing: This test measures the total amount of air in your lungs. It can help diagnose restrictive lung diseases, such as pulmonary fibrosis or sarcoidosis.
3. Diffusion capacity testing: This test measures how well oxygen moves from your lungs into your bloodstream. It's often used to diagnose and monitor conditions like pulmonary fibrosis, interstitial lung disease, and other lung diseases that affect the ability of the lungs to transfer oxygen to the blood.
4. Bronchoprovocation testing: This test involves inhaling a substance that can cause your airways to narrow, such as methacholine or histamine. It's often used to diagnose and monitor asthma.
5. Exercise stress testing: This test measures how well your lungs and heart work together during exercise. It's often used to diagnose lung or heart disease.

Overall, Respiratory Function Tests are an important tool for diagnosing and managing a wide range of lung conditions.

Forced Expiratory Volume (FEV) is a medical term used to describe the volume of air that can be forcefully exhaled from the lungs in one second. It is often measured during pulmonary function testing to assess lung function and diagnose conditions such as chronic obstructive pulmonary disease (COPD) or asthma.

FEV is typically expressed as a percentage of the Forced Vital Capacity (FVC), which is the total volume of air that can be exhaled from the lungs after taking a deep breath in. The ratio of FEV to FVC is used to determine whether there is obstruction in the airways, with a lower ratio indicating more severe obstruction.

There are different types of FEV measurements, including FEV1 (the volume of air exhaled in one second), FEV25-75 (the average volume of air exhaled during the middle 50% of the FVC maneuver), and FEV0.5 (the volume of air exhaled in half a second). These measurements can provide additional information about lung function and help guide treatment decisions.

A cough is a reflex action that helps to clear the airways of irritants, foreign particles, or excess mucus or phlegm. It is characterized by a sudden, forceful expulsion of air from the lungs through the mouth and nose. A cough can be acute (short-term) or chronic (long-term), and it can be accompanied by other symptoms such as chest pain, shortness of breath, or fever. Coughing can be caused by various factors, including respiratory infections, allergies, asthma, environmental pollutants, gastroesophageal reflux disease (GERD), and chronic lung diseases such as chronic obstructive pulmonary disease (COPD) and bronchitis. In some cases, a cough may be a symptom of a more serious underlying condition, such as heart failure or lung cancer.

Bronchitis is a medical condition characterized by inflammation of the bronchi, which are the large airways that lead to the lungs. This inflammation can cause a variety of symptoms, including coughing, wheezing, chest tightness, and shortness of breath. Bronchitis can be either acute or chronic.

Acute bronchitis is usually caused by a viral infection, such as a cold or the flu, and typically lasts for a few days to a week. Symptoms may include a productive cough (coughing up mucus or phlegm), chest discomfort, and fatigue. Acute bronchitis often resolves on its own without specific medical treatment, although rest, hydration, and over-the-counter medications to manage symptoms may be helpful.

Chronic bronchitis, on the other hand, is a long-term condition that is characterized by a persistent cough with mucus production that lasts for at least three months out of the year for two consecutive years. Chronic bronchitis is typically caused by exposure to irritants such as cigarette smoke, air pollution, or occupational dusts and chemicals. It is often associated with chronic obstructive pulmonary disease (COPD), which includes both chronic bronchitis and emphysema.

Treatment for chronic bronchitis may include medications to help open the airways, such as bronchodilators and corticosteroids, as well as lifestyle changes such as smoking cessation and avoiding irritants. In severe cases, oxygen therapy or lung transplantation may be necessary.

Vital capacity (VC) is a term used in pulmonary function tests to describe the maximum volume of air that can be exhaled after taking a deep breath. It is the sum of inspiratory reserve volume, tidal volume, and expiratory reserve volume. In other words, it's the total amount of air you can forcibly exhale after inhaling as deeply as possible. Vital capacity is an important measurement in assessing lung function and can be reduced in conditions such as chronic obstructive pulmonary disease (COPD), asthma, and other respiratory disorders.

Mucus is a viscous, slippery secretion produced by the mucous membranes that line various body cavities such as the respiratory and gastrointestinal tracts. It serves to lubricate and protect these surfaces from damage, infection, and foreign particles. Mucus contains water, proteins, salts, and other substances, including antibodies, enzymes, and glycoproteins called mucins that give it its characteristic gel-like consistency.

In the respiratory system, mucus traps inhaled particles such as dust, allergens, and pathogens, preventing them from reaching the lungs. The cilia, tiny hair-like structures lining the airways, move the mucus upward toward the throat, where it can be swallowed or expelled through coughing or sneezing. In the gastrointestinal tract, mucus helps protect the lining of the stomach and intestines from digestive enzymes and other harmful substances.

Excessive production of mucus can occur in various medical conditions such as allergies, respiratory infections, chronic lung diseases, and gastrointestinal disorders, leading to symptoms such as coughing, wheezing, nasal congestion, and diarrhea.

Common Variable Immunodeficiency (CVID) is a type of primary immunodeficiency disorder characterized by reduced levels of immunoglobulins (also known as antibodies) in the blood, which makes an individual more susceptible to infections. The term "common" refers to its prevalence compared to other types of immunodeficiencies, and "variable" indicates the variability in the severity and types of symptoms among affected individuals.

Immunoglobulins are proteins produced by the immune system to help fight off infections caused by bacteria, viruses, and other pathogens. In CVID, there is a deficiency in the production or function of these immunoglobulins, particularly IgG, IgA, and/or IgM. This results in recurrent infections, chronic inflammation, and an increased risk of developing autoimmune disorders and cancer.

Symptoms of CVID can include:

1. Recurrent sinus, ear, and lung infections
2. Gastrointestinal issues, such as diarrhea, bloating, and malabsorption
3. Autoimmune disorders, like rheumatoid arthritis, lupus, or inflammatory bowel disease
4. Increased risk of certain cancers, particularly lymphomas
5. Fatigue and poor growth in children
6. Delayed puberty in adolescents
7. Lung damage due to recurrent infections
8. Poor response to vaccinations

The exact cause of CVID is not fully understood, but it is believed to be related to genetic factors. In some cases, a family history of immunodeficiency disorders may be present. Diagnosis typically involves blood tests to measure immunoglobulin levels and other immune system components, as well as genetic testing to identify any known genetic mutations associated with CVID. Treatment usually consists of regular infusions of immunoglobulins to replace the missing antibodies and help prevent infections.

Suppuration is the process of forming or discharging pus. It is a condition that results from infection, tissue death (necrosis), or injury, where white blood cells (leukocytes) accumulate to combat the infection and subsequently die, forming pus. The pus consists of dead leukocytes, dead tissue, debris, and microbes (bacteria, fungi, or protozoa). Suppuration can occur in various body parts such as the lungs (empyema), brain (abscess), or skin (carbuncle, furuncle). Treatment typically involves draining the pus and administering appropriate antibiotics to eliminate the infection.

Pseudomonas infections are infections caused by the bacterium Pseudomonas aeruginosa or other species of the Pseudomonas genus. These bacteria are gram-negative, opportunistic pathogens that can cause various types of infections, including respiratory, urinary tract, gastrointestinal, dermatological, and bloodstream infections.

Pseudomonas aeruginosa is a common cause of healthcare-associated infections, particularly in patients with weakened immune systems, chronic lung diseases, or those who are hospitalized for extended periods. The bacteria can also infect wounds, burns, and medical devices such as catheters and ventilators.

Pseudomonas infections can be difficult to treat due to the bacteria's resistance to many antibiotics. Treatment typically involves the use of multiple antibiotics that are effective against Pseudomonas aeruginosa. In severe cases, intravenous antibiotics or even hospitalization may be necessary.

Prevention measures include good hand hygiene, contact precautions for patients with known Pseudomonas infections, and proper cleaning and maintenance of medical equipment.

Lung diseases refer to a broad category of disorders that affect the lungs and other structures within the respiratory system. These diseases can impair lung function, leading to symptoms such as coughing, shortness of breath, chest pain, and wheezing. They can be categorized into several types based on the underlying cause and nature of the disease process. Some common examples include:

1. Obstructive lung diseases: These are characterized by narrowing or blockage of the airways, making it difficult to breathe out. Examples include chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, and cystic fibrosis.
2. Restrictive lung diseases: These involve stiffening or scarring of the lungs, which reduces their ability to expand and take in air. Examples include idiopathic pulmonary fibrosis, sarcoidosis, and asbestosis.
3. Infectious lung diseases: These are caused by bacteria, viruses, fungi, or parasites that infect the lungs. Examples include pneumonia, tuberculosis, and influenza.
4. Vascular lung diseases: These affect the blood vessels in the lungs, impairing oxygen exchange. Examples include pulmonary embolism, pulmonary hypertension, and chronic thromboembolic pulmonary hypertension (CTEPH).
5. Neoplastic lung diseases: These involve abnormal growth of cells within the lungs, leading to cancer. Examples include small cell lung cancer, non-small cell lung cancer, and mesothelioma.
6. Other lung diseases: These include interstitial lung diseases, pleural effusions, and rare disorders such as pulmonary alveolar proteinosis and lymphangioleiomyomatosis (LAM).

It is important to note that this list is not exhaustive, and there are many other conditions that can affect the lungs. Proper diagnosis and treatment of lung diseases require consultation with a healthcare professional, such as a pulmonologist or respiratory therapist.

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

Inflammation is a complex biological response of tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. It is characterized by the following signs: rubor (redness), tumor (swelling), calor (heat), dolor (pain), and functio laesa (loss of function). The process involves the activation of the immune system, recruitment of white blood cells, and release of inflammatory mediators, which contribute to the elimination of the injurious stimuli and initiation of the healing process. However, uncontrolled or chronic inflammation can also lead to tissue damage and diseases.

Obstructive lung disease is a category of respiratory diseases characterized by airflow limitation that causes difficulty in completely emptying the alveoli (tiny air sacs) of the lungs during exhaling. This results in the trapping of stale air and prevents fresh air from entering the alveoli, leading to various symptoms such as coughing, wheezing, shortness of breath, and decreased exercise tolerance.

The most common obstructive lung diseases include:

1. Chronic Obstructive Pulmonary Disease (COPD): A progressive disease that includes chronic bronchitis and emphysema, often caused by smoking or exposure to harmful pollutants.
2. Asthma: A chronic inflammatory disorder of the airways characterized by variable airflow obstruction, bronchial hyperresponsiveness, and an underlying inflammation. Symptoms can be triggered by various factors such as allergens, irritants, or physical activity.
3. Bronchiectasis: A condition in which the airways become abnormally widened, scarred, and thickened due to chronic inflammation or infection, leading to mucus buildup and impaired clearance.
4. Cystic Fibrosis: An inherited genetic disorder that affects the exocrine glands, resulting in thick and sticky mucus production in various organs, including the lungs. This can lead to chronic lung infections, inflammation, and airway obstruction.
5. Alpha-1 Antitrypsin Deficiency: A genetic condition characterized by low levels of alpha-1 antitrypsin protein, which leads to uncontrolled protease enzyme activity that damages the lung tissue, causing emphysema-like symptoms.

Treatment for obstructive lung diseases typically involves bronchodilators (to relax and widen the airways), corticosteroids (to reduce inflammation), and lifestyle modifications such as smoking cessation and pulmonary rehabilitation programs. In severe cases, oxygen therapy or even lung transplantation may be considered.

... without CF is known as non-CF bronchiectasis. Historically, about half of all case of non-CF bronchiectasis were ... and cystic bronchiectasis. Bronchiectasis primarily in the middle lobe of the right lung. Bronchiectasis secondary to a large ... Bronchiectasis may also present with coughing up blood in the absence of sputum, which has been called "dry bronchiectasis." ... Bronchiectasis Imaging at eMedicine Pasteur, M. C.; Bilton, D.; Hill, A. T.; British Thoracic Society Bronchiectasis non-CF ...
It is seen in cases of pneumonia, bronchiectasis, lung abscess, or an advanced stage of bronchitis. Sputum can be (when ... Massive blood - an indicator of possible cavitary tuberculosis or tumor such as lung cancer, or lung abscess; bronchiectasis; ... and infected bronchiectasis or cystic fibrosis. Rust colored - usually caused by pneumococcal bacteria (in pneumonia), ...
Bronchiectasis "Radiopedia". Yousem DM; Grossman RI (2010). Neuroradiology: The Requisites. Elsevier Health Sciences. p. 480. ...
He has been the founder member of European Registry of Bronchiectasis (EMBARC), Italian Bronchiectasis Registry (IRIDE) and ... Bronchiectasis. United Kingdom: European Respiratory Society, 2018. Palange, Paolo., Rohde, Gernot. ERS Handbook of Respiratory ... Blasi has been nominated as the chair of scientific committee of World Bronchiectasis Conference in 2017. ... "EMBARC - EMBARC Committee". www.bronchiectasis.eu. Retrieved 2020-11-21. "Faculty - Lung health 2019". Retrieved 2020-11-21. " ...
McCallion P, De Soyza A (December 2017). "Cough and bronchiectasis". Pulmonary Pharmacology & Therapeutics. 47: 77-83. doi: ...
Bronchiectasis has three major anatomical patterns: cylindrical bronchiectasis, varicose bronchiectasis and cystic ... Bronchiectasis refers to the abnormal, irreversible dilatation of the bronchi caused by destructive and inflammatory changes in ... "What Is Bronchiectasis?". NHLBI. June 2, 2014. Archived from the original on 10 August 2016. Retrieved 10 August 2016. ... Types of obstructive lung disease include; asthma, bronchiectasis, bronchitis and chronic obstructive pulmonary disease (COPD ...
Asthma, bronchiectasis, and chronic obstructive pulmonary disease (COPD) that includes chronic bronchitis, and emphysema, are ... A common cause of chronic bronchitis, and emphysema, is smoking; and common causes of bronchiectasis include severe infections ... "8 Interesting Facts About Lungs". Bronchiectasis News Today. 2016-10-17. Retrieved 2020-05-05. Notter, Robert H. (2000). Lung ... Treatment with thoracoscopic lobectomy/segmentectomy for right middle lobe and lingular bronchiectasis associated with non- ...
Approximately 40% will also have bronchiectasis. It is also associated with chronic sinusitis and persistent coughing. It ... all people with yellow nail syndrome have either recurrent chest infections or a chronic lung condition known as bronchiectasis ...
Whether the bronchiectasis leads to the MAC infection or is the result of it is not always known. The Mycobacterium avium ... Bronchiectasis, the bronchial condition which causes pathological enlargement of the bronchial tubes, is commonly found with ... December 2005). "Non-tuberculous mycobacteria in patients with bronchiectasis". Thorax. 60 (12): 1045-51. doi:10.1136/thx. ... ISBN 978-1-4051-3377-7. Ebihara, Takae; Sasaki, Hidetada (2002). "Bronchiectasis with Mycobacterium avium Complex Infection". ...
We have presumed that the nail dystrophy and the congenital change leading to chronic bronchiectasis are allied, but a lack of ... The link between shell nail syndrome and bronchiectasis is present within the first description of the syndrome. The patient, a ... The concurrence of the syndrome and bronchiectasis is well-established, however the exact causes of the deformity remains ... Shell nail syndrome is a medical condition defined by the concurrence of large, rounded fingernails and bronchiectasis. Despite ...
An association between male sterility and bronchiectasis". West. J. Med. 144 (6): 744-6. PMC 1306774. PMID 3727536. v t e ( ... is a rare condition that encompasses a combination of syndromes such as bronchiectasis, rhinosinusitis and reduced male ...
David Sheldon, 54, American professional wrestler ("Angel of Death"). David H. Shepard, 84, American inventor, bronchiectasis. ...
Chest percussion and postural drainage are used in bronchiectasis and lung abscess. The patient's body is positioned so that ... Postural drainage is essential in treating bronchiectasis. Patients must receive physiotherapy to learn to tip themselves into ...
... including bronchiectasis and sarcoidosis. Despite the severity of a patient's respiratory condition, certain pre-existing ...
Bronchiectasis of left lower lobe of lungs; extirpation of diseased lung tissue (31 min; color). PMF 5066 - PMF 5067 - PMF 5068 ...
Bronchiectasis is bronchial dilation with bronchial wall thickening. Chest x-ray showing course bronchiectasis of the lungs ... Bronchiectasis and pleural scarring may be present.[citation needed] Nodules and fibrotic scars may contain slowly multiplying ... 5. Other-Any other finding suggestive of prior TB, such as upper lobe bronchiectasis. ...
Other causes of similar symptoms include asthma, pneumonia, bronchiolitis, bronchiectasis, and COPD. A chest X-ray may be ... Advanced cases may show imaging similarities to bronchiectasis. Aspergillus bronchitis is one of the Aspergillosis spectrum of ... Mosby (Elsevier). Chapter 33: Bronchitis, Bronchiectasis, and Cystic Fibrosis. ISBN 978-0323025737. Foster, W (2002). " ...
Untreated DPB leads to bronchiectasis, respiratory failure, and death. A journal report from 1983 indicated that untreated DPB ... If left untreated, DPB progresses to bronchiectasis, an irreversible lung condition that involves enlargement of the ... bronchiectasis will occur; it is characterized by dilation and thickening of the walls of the bronchioles, inflammatory damage ...
Terence Edmond, 69, British actor (Z-Cars), bronchiectasis. Ronald Max Hartwell, 88, Australian economic historian. Citizen ...
It is presumed it was given to treat his bronchiectasis. In June 1949 Nineteen Eighty-Four was published, to critical acclaim. ... bronchiectasis, and infertility: what ailed George Orwell?". Clin Infect Dis. 41 (11): 1599-1603. doi:10.1086/497838. PMID ...
Mediastinal lymphadenopathy and bronchiectasis may also be seen. Precise distribution and types of tissue damage differ among ...
It is a form of congenital cystic bronchiectasis. This leads to collapse of the airways and bronchiectasis. It acts as one of ... In 1976, the first report of the occurrence of familial bronchiectasis in siblings was published, and it supported the theory ... conducted a systematic review, aiming to answer what are the effects of treatments in people with bronchiectasis but without ... Mitra S, Chowdhury AR, Bandyopadhyay G (2015). "Williams-Campbell syndrome-a rare entity of congenital bronchiectasis: A case ...
... atelectasis and bronchiectasis. One reason aspiration can occur is because of failure of the epiglottis to close completely. ...
By the 1980s she was diagnosed with bronchiectasis. As a complication of her tuberculosis, she went blind in one eye in 2013. ...
... bronchiectasis. Felix Ayo, 90, Spanish-born Italian violinist (I Musici). Keith Baxter, 90, Welsh actor (Chimes at Midnight, ...
ATP2A1 Bronchiectasis with or without elevated sweat chloride 1; 211400; SCNN1B Bronchiectasis with or without elevated sweat ... chloride 2; 613021; SCNN1A Bronchiectasis with or without elevated sweat chloride 3; 613071; SCNN1G Brooke-Spiegler syndrome; ...
Recurrent infections may lead to the development of bronchiectasis. The syndrome is caused by mutations in the phospholipase C ...
He was the first person to report a case of bronchiectasis with situs inversus, in 1904, although he reported it in a Russian ... Kartagener, M. (September 1933). "Zur Pathogenese der Bronchiektasien" [On the pathogenesis of bronchiectasis]. Beiträge zur ... About a case of bronchiectasis in a patient with situs inversus viscerum]. Berliner klinische Wochenschrift (in German). 41: ...
His death was attributed to bronchiectasis and chronic nephritis. Haines was a pioneer in adapting medical techniques from the ...
"Bronchiectasis Treatment & Management: Approach Considerations, Supportive Treatment, Antibiotic Therapy". 17 February 2017. ... bronchiectasis and lymphoproliferation.[medical citation needed] The signs and symptoms of activated PI3K Delta Syndrome are ... consistent with the following: Immunodeficiency Lymphadenopathy Sinopulmonary infections Bronchiectasis In terms of genetics, ...
Bronchiectasis without CF is known as non-CF bronchiectasis. Historically, about half of all case of non-CF bronchiectasis were ... and cystic bronchiectasis. Bronchiectasis primarily in the middle lobe of the right lung. Bronchiectasis secondary to a large ... Bronchiectasis may also present with coughing up blood in the absence of sputum, which has been called "dry bronchiectasis." ... Bronchiectasis Imaging at eMedicine Pasteur, M. C.; Bilton, D.; Hill, A. T.; British Thoracic Society Bronchiectasis non-CF ...
Bronchiectasis is a disease in which the large airways in the lungs are damaged. This causes the airways to become permanently ... Bronchiectasis is a disease in which the large airways in the lungs are damaged. This causes the airways to become permanently ... Other causes of bronchiectasis can include:. *Cystic fibrosis, a disease that causes thick, sticky mucus to build up in the ... Bronchiectasis is a disease in which the large airways in the lungs are damaged. This causes the airways to become permanently ...
Bronchiectasis in Childhood Br Med J 1963; 1 :80 doi:10.1136/bmj.1.5323.80 ... Bronchiectasis in Childhood. Br Med J 1963; 1 doi: https://doi.org/10.1136/bmj.1.5323.80 (Published 12 January 1963) Cite this ...
... N Engl J Med. 2002 May 2;346(18):1383-93. doi: 10.1056/NEJMra012519. ...
This fact sheet describes bronchiectasis, including how it affects breathing, what causes it, and how its diagnosed and ... This fact sheet describes bronchiectasis, including how it affects breathing, what causes it, and how its diagnosed and ...
In 1950, Reid characterized bronchiectasis as cylindrical, cystic, or varicose in nature. ... Bronchiectasis is an uncommon disease, most often secondary to an infectious process, that results in the abnormal and ... The pathogenesis of bronchiectasis in these patients is believed to be similar to that of bronchiectasis in CF. The criterion ... Noteworthy CT findings in bronchiectasis include the following:. * Cylindrical bronchiectasis has parallel tram track lines, or ...
... Int J Clin Pract. 2002 Jan-Feb;56(1):34-5. ... There is a clear need for research into the effectiveness of physiotherapy techniques in bronchiectasis including a cost- ... and there are no national guidelines on the physiotherapy management of patients with bronchiectasis. ... selected hospitals providing respiratory care in the UK were sent a previously piloted questionnaire on their bronchiectasis ...
... and some people have both COPD and bronchiectasis. What researchers do know is that bronchiectasis can have a more significant ... we turn our attention to how bronchiectasis uniquely affects women and the impact that has on gender equality in healthcare and ... what can be done.As we noted in a previous blog post, bronchiectasis is often difficult to diagnose because it can have similar ... approach to treating bronchiectasis. When treating females with bronchiectasis, providers must account for differences so they ...
Validation of the Bronchiectasis Impact Measure (BIM): a novel patient-reported outcome measure Megan L. Crichton, Emily K. ... Sputum neutrophil elastase associates with microbiota and Pseudomonas aeruginosa in bronchiectasis Martina Oriano, Andrea ... Efficacy and safety of TOBI Podhaler in Pseudomonas aeruginosa-infected bronchiectasis patients: iBEST study Michael R. ... Inhaled aztreonam improves symptoms of cough and sputum production in patients with bronchiectasis: a post hoc analysis of the ...
Digital approaches and how they can be applied to bronchiectasis. *Bronchiectasis through the life stages - from childhood to ... how bronchiectasis affects people through different life stages. Attendees will also have an opportunity to ask the speakers ... This years Bronchiectasis Patient Conference will take place online on Sunday 12 March 2023 at 10:00-16:00 CET. ... The conference is for people living with bronchiectasis and their family members and carers. It is an opportunity to understand ...
Has information changed over the years on bronchiectasis? Tune in to learn more. ... What we now know is that non-CF bronchiectasis is not a rare disease. In the U.S. alone, there are up to 500,000 adults ... So starting off, there have been a lot of changes in recent years and what we know about non-CF bronchiectasis. For instance, ... Non-CF Bronchiectasis (NCFBE): Redefined. Be part of the knowledge.â„¢. *Log In ...
MAINIERI-HIDALGO, José Alberto. Bronchiectasis, Results of Surgical Intervention in 36 Patients. Acta méd. costarric [online]. ...
The effects of anticholinergic drugs in the treatment of bronchiectasis. Bronchiectasis is a chronic respiratory disease. ... No formal recommendations can be made about the use of anticholinergic therapy in acute or stable bronchiectasis based on the ... Lasserson TJ, Holt K, Evans DJ, Milan SJ, Greenstone M. Anticholinergic therapy for bronchiectasis. Cochrane Database of ... To determine the effect of anticholinergic therapy in acute exacerbations and stable bronchiectasis. ...
bronchiectasis. Pulmonary rehabilitation is a multidisciplinary approach to treating patients with chronic lung disease and is ... Bronchiectasis. In: Brewis RAL, Gibson GJ, Geddes D, eds. Respiratory medicine. London: Balliere Tindall, 1990:726-59. ... Bronchiectasis is a chronic (often suppurative) lung disease not traditionally included in the definition of COPD, but also ... This is the first study to investigate the effects of exercise training in patients with bronchiectasis. It has shown that the ...
Pulmonary rehabilitation in bronchiectasis: a propensity-matched study. Suhani Patel, Aaron D. Cole, Claire M. Nolan, Ruth E. ... Pulmonary rehabilitation in bronchiectasis: a propensity-matched study. Suhani Patel, Aaron D. Cole, Claire M. Nolan, Ruth E. ... Pulmonary rehabilitation in bronchiectasis: a propensity-matched study. Suhani Patel, Aaron D. Cole, Claire M. Nolan, Ruth E. ... Pulmonary rehabilitation in bronchiectasis: a propensity-matched study Message Subject (Your Name) has sent you a message from ...
Bronchiectasis causes a dialation of the airways accompanied with inflammation and scar tissue. In addition to cystic fibrosis ... In an interview with HCPLive, Flume spoke about the current clinical and research landscape of bronchiectasis, a rare disease ... I started getting referrals of patients who had bronchiectasis, and decided we really needed to create some greater structure, ... Patrick Flume, MD: Could a Persistent Cough be Bronchiectasis?. July 20, 2022. Giuliana Grossi ...
HFCWO using the Philips InCourage System reduced hospitalizations for non-cystic fibrosis bronchiectasis patients by more than ... Philips HFCWO Vest Cut Hospitalizations for Non-CF Bronchiectasis Patients. Jul 23, 2020 , Chronic Pulmonary Disorders, Other ... This data repository is now the largest bronchiectasis research registry in the world. This study observed chronic respiratory ... The study examined data from a registry of adult bronchiectasis patients self-reported outcomes collected by RespirTech, a ...
Bronchiectasis often presents with recurrent pulmonary infections, including a chronic daily productive cough with mucopurulent ... Bronchiectasis is the abnormal dilation of bronchi due to the destruction of the elastic and muscular components of the ... Bronchiectasis often presents with recurrent pulmonary infections, including a chronic daily productive cough with mucopurulent ... Chronic cough due to bronchiectasis: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 suppl):122S-31S. ...
Validity of Diagnosis Code-Based Claims to Identify Pulmonary NTM Disease in Bronchiectasis Patients Jennifer H. Ku. , Emily M ... BRR, Bronchiectasis and NTM Research Registry; NTM, nontuberculous mycobacteria; ICD-9-CM, International Classification of ... Validity of Diagnosis Code-Based Claims to Identify Pulmonary NTM Disease in Bronchiectasis Patients. ... of ICD-9-CM diagnosis code-based case definitions for NTM infection in 2006-2014 Medicare data by using Bronchiectasis and NTM ...
Zea-Vera, A. F., & Agudelo-Rojas, O. L. (2015). Disseminated bronchiectasis in an adult with Common Variable Immunodeficiency. ... Shoemark A, Ozerovitch L, Wilson R. Aetiology in adult patients with bronchiectasis. Respir Med. 2007; 101(6): 1163-70. ... He complained of recurring pneumonia associated with widespread bronchiectasis since he was 18 years old. Serum immunoglobulins ... The initial evaluation of adults with bronchiectasis. Clin Chest Med. 2012; 33(2): 219-31. ...
Spanish Guidelines on Treatment of Bronchiectasis in Adults Normativa sobre el tratamiento de las bronquiectasias en el adulto ... The guidelines are focused on the treatment of bronchiectasis from both a multidisciplinary perspective, including specialty ... published the first guidelines in the world on the diagnosis and treatment of bronchiectasis. Almost 10 years later, ... and the original guidelines have been updated to include the latest therapies available for bronchiectasis. These new ...
Lower lobe bronchiectasis is the commonest zonal predilection in bronchiectasis 2. It is mostly idiopathic but can be typically ... Bronchiectasis. AJR Am J Roentgenol. 2009;193 (3): W158-71. AJR Am J Roentgenol (full text) - doi:10.2214/AJR.09.3053 - Pubmed ... Lower lobe bronchiectasis. Last revised by Bruno Di Muzio â—‰ â—ˆ on 26 Jul 2020 ... 1. Javidan-Nejad C, Bhalla S. Bronchiectasis. Thorac Surg Clin. 2010;20 (1): 85-102. doi:10.1016/j.thorsurg.2009.12.007 - ...
Bronchiectasis oligospermia: a rare syndrome characterized by the association of bronchiectasis (enlarged bronchial airways) ...
Bronchiectasis: Homeopathic Management in a 62-year-old Female. Home / Cardiopulmonary Medicine / Bronchiectasis: Homeopathic ... Bronchiectasis: Homeopathic Management in a 62-year-old Female. By Editor1 Posted October 29, 2014 In Cardiopulmonary Medicine ... Bronchiectasis is characterized by the irreversible dilation and damage of airways due to inflammatory destruction and ... Here we present a case of homeopathic treatment for severe bronchiectasis in a 62-year-old Hispanic female. The patient was ...
Certain purebred dogs and older dogs may have an increased risk of developing bronchiectasis. (J Am Vet Med Assoc 2003;223:1628 ... Median duration of clinical signs prior to diagnosis of bronchiectasis was 9 months (range, 1 day to 10 years). Median survival ... On thoracic radiographs, cylindrical bronchiectasis, generalized disease, and right cranial lung lobe involvement were most ... 10 years old had an increased risk of bronchiectasis. Among dogs examined at the teaching hospital, coughing was the most ...
Participants will be asked to donate a stool sample a sputum sample (bronchiectasis patients only) and a blood sample which ... The gut microbiome in rheumatoid arthritis and bronchiectasis. *. Research type. Research Study ... Towards functional correlates of microbiota and immune phenotype in rheumatoid arthritis and bronchiectasis. ... also look at the gut/lung microbiome and white blood cell phenotype in a group of patients who have both RA and bronchiectasis ...
Despite paediatric bronchiectasis being recognized increasingly worldwide, prior reports of hospitalization costs for ... The per episode healthcare cost burden of hospitalizations for paediatric bronchiectasis exacerbations is substantial. ... Interventions that prevent hospitalized exacerbations and reduce severity of childhood bronchiectasis with even moderate ... bronchiectasis in children are lacking. This study aimed to (i) identify health service costs of hospitalizations and (ii) ...
The microbiome in bronchiectasis. Hollian Richardson, Alison J. Dicker, Heather Barclay, James D. Chalmers ...
Radiograph showing bronchiectasis. Last reviewed dd mmm yyyy. Last edited dd mmm yyyy ...
  • Exacerbations in bronchiectasis present as a worsening of cough, increasing sputum volume or thickened consistency lasting at least 48 hours, worsening shortness of breath (breathlessness), worsening exercise intolerance, increased fatigue or malaise and the development of hemoptysis. (wikipedia.org)
  • To determine the effect of anticholinergic therapy in acute exacerbations and stable bronchiectasis. (cochrane.org)
  • The per episode healthcare cost burden of hospitalizations for paediatric bronchiectasis exacerbations is substantial. (asthmafoundation.org.nz)
  • Interventions that prevent hospitalized exacerbations and reduce severity of childhood bronchiectasis with even moderate effectiveness are likely to result in substantial hospital costs savings. (asthmafoundation.org.nz)
  • We know that the level of lung inflammation is important for long term health in bronchiectasis, so we wanted to know whether the sputum colour, when assessed when the patient is healthy with no chest infection, had any relationship to long-term outcomes such as lung function and frequency and severity of exacerbations. (thesynapse.net)
  • Effect of azithromycin maintenance treatment on infectious exacerbations among patients with non-cystic fibrosis bronchiectasis: the BAT randomized controlled trial. (thoracic.org)
  • Bilton D, Henig N, Morrissey B, Gotfried M (2006) Addition of inhaled tobramycin to ciprofloxacin for acute exacerbations of Pseudomonas aeruginosa infection in adult bronchiectasis. (bronchiectasis.com.au)
  • Exacerbations in non-cystic fibrosis bronchiectasis: clinical features and investigations. (bronchiectasis.com.au)
  • Reducing mucus in the lungs has also been associated with fewer bronchiectasis exacerbations, thus allowing patients to live free from symptoms or with fewer symptoms from day to day. (afflovest.com)
  • The goal of long-term management of bronchiectasis is to control symptoms and prevent exacerbations, and includes pulmonary physiotherapy and pharmacological therapy. (amboss.com)
  • Hemoptysis (coughing up blood) can occur, especially during acute exacerbations or when bronchiectasis is severe. (ayurvedguru.com)
  • We looked for randomised studies addressing this question but we could not identify any evidence for or against the use of anticholinergic drugs in the treatment of bronchiectasis. (cochrane.org)
  • In 2008, the Spanish Society of Pulmonology (SEPAR) published the first guidelines in the world on the diagnosis and treatment of bronchiectasis. (archbronconeumol.org)
  • Early and effective treatment of bronchiectasis in childhood will ultimately lead to improved health outcomes and quality of life throughout life. (telethonkids.org.au)
  • Davies G, Wilson R. Prophylactic antibiotic treatment of bronchiectasis with azithromycin. (medscape.com)
  • Bronchiectasis is a disease in which there is permanent enlargement of parts of the airways of the lung. (wikipedia.org)
  • Bronchiectasis is a disease in which the large airways in the lungs are damaged. (medlineplus.gov)
  • Bronchiectasis is often caused by inflammation or infection of the airways that keeps coming back. (medlineplus.gov)
  • Bronchiectasis is an uncommon disease, most often secondary to an infectious process, that results in the abnormal and permanent distortion of one or more of the conducting bronchi or airways. (medscape.com)
  • Atrovent and other anticholinergic agents are bronchodilators which could help with opening up the airways in people with bronchiectasis. (cochrane.org)
  • Bronchiectasis causes a dialation of the airways accompanied with inflammation and scar tissue. (hcplive.com)
  • Bronchiectasis oligospermia: a rare syndrome characterized by the association of bronchiectasis (enlarged bronchial airways) and a defect in the sperm ducts which affects the number of sperm produced. (checkorphan.org)
  • Bronchiectasis is characterized by the irreversible dilation and damage of airways due to inflammatory destruction and subsequent remodeling of airway walls. (ndnr.com)
  • The aim of our study was to characterise the lipids obtained from serum and airways in bronchiectasis patients in the stable state. (ed.ac.uk)
  • LXA4 improved blood and airways neutrophil phagocytosis and bacterial killing in bronchiectasis patients. (ed.ac.uk)
  • Bronchiectasis is an ailment wherein the airways that transport air into and out of the lungs get adversely affected, leading airways to enlarge and become loosened and scarred. (reportsanddata.com)
  • Bronchiectasis is caused by an infection or another disorder that damages the walls of the airways or inhibits the airways from clearing mucus. (reportsanddata.com)
  • The initial damage to airways that develops to bronchiectasis typically begins in childhood. (reportsanddata.com)
  • Repeated or severe respiratory infections, such as pneumonia, whooping cough (pertussis), and tuberculosis, can cause damage to the airways and contribute to the development of bronchiectasis. (ayurvedguru.com)
  • Inhalation of a foreign object, such as a small toy or food, can cause bronchiectasis if it becomes lodged in the airways. (ayurvedguru.com)
  • Bronchiectasis (bron-kee-ek'-tas-is) is a lung disease that usually results from an infection or other condition that injures the walls of the airways in your lungs. (copdsupport.ie)
  • Inflammation or recurrent infections of the airways are common causes of bronchiectasis. (medanta.org)
  • However, bronchitis is a transient illness that doesn't permanently expand your airways, but bronchiectasis does. (medanta.org)
  • Bronchiectasis is a condition that occurs when the airways are damaged, causing them to widen and become scarred. (breathepa.org)
  • As we noted in a previous blog post , bronchiectasis is often difficult to diagnose because it can have similar symptoms to COPD, and some people have both COPD and bronchiectasis. (copdfoundation.org)
  • Other factors that can lead to women being impacted earlier than men include the tendency to develop bronchiectasis in the first place (just like women are more likely to have COPD) and genetic factors, such as how the body changes over time. (copdfoundation.org)
  • Bronchiectasis is a chronic (often suppurative) lung disease not traditionally included in the definition of COPD, but also characterised by airflow obstruction and symptoms including cough, sputum production, wheeze, dyspnoea, and decreased exercise tolerance. (bmj.com)
  • 8 Theoretically, one would therefore expect pulmonary rehabilitation to be as effective in bronchiectasis as it is in COPD, but to date only one study has been performed which included only seven patients with the disease. (bmj.com)
  • Chronic respiratory conditions, like bronchiectasis and COPD, contribute to significant healthcare costs each year between hospitalizations and readmissions. (rtmagazine.com)
  • Current Australian and NZ physiotherapy practice in the management of patients with chronic bronchiectasis and COPD. (bronchiectasis.com.au)
  • Bronchiectasis is classified according to etiology as either cystic fibrosis ( CF ) bronchiectasis or non- CF bronchiectasis (e.g., secondary to severe or protracted pneumonia , immunodeficiency , or COPD ). (amboss.com)
  • Bronchiectasis is one of the chronic obstructive pulmonary diseases (COPD)* and it can be complicated by emphysema and bronchitis. (copdsupport.ie)
  • This year's Bronchiectasis Patient Conference will take place online on Sunday 12 March 2023 at 10:00-16:00 CET. (eswi.org)
  • For instance, we used to think that bronchiectasis was a rare disease with around 100,000 to 150,000 patients in the U.S. We used to think that most cases of bronchiectasis were caused by past infection, such as a pneumonia. (reachmd.com)
  • About 50% of all cases of bronchiectasis in the U.S. result from cystic fibrosis. (copdsupport.ie)
  • Chronic respiratory failure is a term used to describe very serious (advanced) cases of bronchiectasis, which are more common in low- and middle-income countries and in people with advanced cystic fibrosis. (medanta.org)
  • These cases of bronchiectasis can significantly impair breathing and lead to unnaturally low amounts of oxygen and/or elevated amounts of carbon dioxide in the blood. (medanta.org)
  • Causes of Bronchiectasis With Specific Treatment. (archbronconeumol.org)
  • Specifically, allergic bronchopulmonary aspergillosis, atypical mycobacterial infections, immunodeficiency states, and autoimmune diseases are causes of bronchiectasis that may be treated effectively once diagnosed. (medscape.com)
  • Median duration of clinical signs prior to diagnosis of bronchiectasis was 9 months (range, 1 day to 10 years). (avma.org)
  • 2014) Inhaled mannitol for non-cystic fibrosis bronchiectasis: A randomised, controlled trial Thorax . (bronchiectasis.com.au)
  • There are many causes that can induce or contribute to the development of bronchiectasis. (wikipedia.org)
  • Historically, about half of all case of non-CF bronchiectasis were found to be idiopathic, or without a known cause. (wikipedia.org)
  • Thirty two patients with idiopathic bronchiectasis were randomly allocated to one of three groups: PR plus sham IMT (PR-SHAM), PR plus targeted IMT (PR-IMT), or control. (bmj.com)
  • Treatment of idiopathic bronchiectasis with aerosolized recombinant human DNase I. Chest 1998;113:1329-1334. (thoracic.org)
  • A large multinational trial of patients with idiopathic bronchiectasis found increased exacerbation frequency and a more brisk decrease in FEV1. (thoracic.org)
  • In some cases, the cause of bronchiectasis remains unknown (idiopathic). (ayurvedguru.com)
  • Bronchiectasis is a chronic suppurative lung disease often characterised by airflow obstruction and hyperinflation, and leading to decreased exercise tolerance and reduced health status. (bmj.com)
  • 2010) Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand. (bronchiectasis.com.au)
  • Bronchiectasis is the abnormal dilation of bronchi due to the destruction of the elastic and muscular components of the bronchial wall. (bmj.com)
  • Reduction in bronchial subdivision in bronchiectasis. (bmj.com)
  • Antimicrobial Treatment in Bronchial Infection in Patients with Bronchiectasis. (archbronconeumol.org)
  • Bronchiectasis is an irreversible and abnormal dilation in the bronchial tree caused by cycles of bronchial inflammation leading to mucous plugging and progressive airway destruction. (amboss.com)
  • Primary prevention of bronchiectasis includes antibiotic control of bronchial and pulmonary infections in predisposed individuals. (amboss.com)
  • Bronchiectasis is a chronic respiratory condition characterized by the widening and inflammation of the bronchial tubes, which can lead to excessive mucus buildup and recurrent infections. (ayurvedguru.com)
  • When you have bronchiectasis, your lungs' bronchial tubes are permanently enlarged, thickened, and damaged. (medanta.org)
  • The complications of bronchiectasis include serious health conditions, such as respiratory failure and atelectasis: collapse or closure of a lung. (wikipedia.org)
  • Senior physiotherapists in 100 randomly selected hospitals providing respiratory care in the UK were sent a previously piloted questionnaire on their bronchiectasis practice. (nih.gov)
  • Bronchiectasis is a chronic respiratory disease. (cochrane.org)
  • The colour of the phlegm from patients with the lung disease bronchiectasis can indicate the degree of inflammation in their lungs and predict their future outcomes, according to new research presented at the European Respiratory Society International Congress in Milan, Italy. (thesynapse.net)
  • Bronchiectasis is one of the most neglected diseases in respiratory medicine. (ersjournals.com)
  • The bronchiectasis treatment market revenue growth is primarily driven by factors such as increase in the number of patients suffering from respiratory diseases and increase in the prevalence of Cigarette smokers. (reportsanddata.com)
  • European Respiratory Society guidelines for the management of adult bronchiectasis. (thoracic.org)
  • Bronchiectasis: a neglected cause of respiratory morbidity and mortality. (medscape.com)
  • While conventional medicine provides treatments for bronchiectasis, Ayurveda, the ancient holistic healing system from India, offers natural remedies and practices that can complement medical interventions and promote respiratory well-being. (ayurvedguru.com)
  • Bronchiectasis is an abnormal stretching and enlarging of the respiratory passages caused by mucus blockage. (copdsupport.ie)
  • CRDs are an emerging public health and the sequelae of respiratory problem in urbanised areas of Low- infections such as occurs after and Middle-income countries tuberculosis, or for instance with bronchiectasis occurring after early childhood infections. (who.int)
  • Cystic fibrosis eventually results in severe bronchiectasis in nearly all cases. (wikipedia.org)
  • Studies have shown that women are more likely to develop bronchiectasis at an earlier age and may have more severe cases of it affecting health and, a poorer lung function. (copdfoundation.org)
  • Maintenance aerosolized antibiotics may be used for treatment of severe bronchiectasis or recurrent Pseudomonas aeruginosa infections. (bmj.com)
  • Here we present a case of homeopathic treatment for severe bronchiectasis in a 62-year-old Hispanic female. (ndnr.com)
  • 6 healthy volunteers, 10 patients with mild, 15 with moderate and 9 with severe bronchiectasis were recruited. (ed.ac.uk)
  • There was a significantly lower level of Lipoxin A4 (LXA4) in severe bronchiectasis. (ed.ac.uk)
  • Furthermore, the avail- aged more than 18 years, with diagnoses based on their physiological parameters able evidence supports the utilization of bronchiectasis, severe uncontrolled and the physiotherapist's judgement. (who.int)
  • Certain purebred dogs and older dogs may have an increased risk of developing bronchiectasis. (avma.org)
  • The conference is for people living with bronchiectasis and their family members and carers. (eswi.org)
  • Shoemark A, Ozerovitch L, Wilson R. Aetiology in adult patients with bronchiectasis. (univalle.edu.co)
  • Aksamit TR et al (2017) Adult patients with bronchiectasis: a first look at the US bronchiectasis research registry. (bronchiectasis.com.au)
  • There is a clear need for research into the effectiveness of physiotherapy techniques in bronchiectasis including a cost-benefit analysis which would enable targeting of resources and the development of evidence-based practice guidelines. (nih.gov)
  • Standard Physiotherapy Techniques in Bronchiectasis. (archbronconeumol.org)
  • When treating females with bronchiectasis, providers must account for differences so they can provide the most effective clinical treatment including access to therapies that work best for them. (copdfoundation.org)
  • In an interview with HCPLive , Flume spoke about the current clinical and research landscape of bronchiectasis, a rare disease that can often present in patients with CF. (hcplive.com)
  • Chronic cough due to bronchiectasis: ACCP evidence-based clinical practice guidelines. (bmj.com)
  • Objective -To determine demographic, clinical, and radiographic features of bronchiectasis in dogs. (avma.org)
  • Conclusions and Clinical Relevance -Results suggest that despite substantial clinical abnormalities, dogs with bronchiectasis may survive for years. (avma.org)
  • We believe that implementation of this biomarker into clinical practice will improve treatment and monitoring of bronchiectasis patients. (thesynapse.net)
  • Non-CF bronchiectasis: clinical and HRCT evaluation. (bronchiectasis.com.au)
  • Hill AT et al (2017) Pulmonary exacerbation in adults with bronchiectasis: a consensus definition for clinical research. (bronchiectasis.com.au)
  • King P, Holdsworth S, Freezer N, Villanueva E, Holmes P (2006) Characterisation of the onset and presenting clinical features of adult bronchiectasis. (bronchiectasis.com.au)
  • Yalçin E, Kiper N, Ozcelik U, Dogru D, Firat P, Sahin A. Effects of claritromycin on inflammatory parameters and clinical conditions in children with bronchiectasis. (medscape.com)
  • Bronchiectasis in Alaska Native children: causes and clinical courses. (medscape.com)
  • Bronchiectasis often presents with recurrent pulmonary infections, including a chronic daily productive cough with mucopurulent sputum production. (bmj.com)
  • Individuals with bronchiectasis are prone to recurrent lung infections, which can lead to increased cough and worsened symptoms. (ayurvedguru.com)
  • Bronchiectasis usually begins in childhood, but symptoms may not appear until months or even years after you have started having repeated lung infections. (copdsupport.ie)
  • If lung infections are treated immediately, bronchiectasis is less likely to develop. (copdsupport.ie)
  • Healthcare professionals manage infections and clean mucus to treat bronchiectasis. (medanta.org)
  • The study, " Real-life experience with high-frequency chest wall oscillation vest therapy in adults with non-cystic fibrosis bronchiectasis " [2], found that initiating airway clearance with noninvasive HFCWO therapy is associated with keeping patients out of the hospital, reducing their need for medications, and improving quality of life. (rtmagazine.com)
  • al, "Real-life experience with high-frequency chest wall oscillation vest therapy in adults with non-cystic fibrosis bronchiectasis. (rtmagazine.com)
  • A trial of chronic azithromycin treatment in patients with stable non-cystic fibrosis bronchiectasis. (thoracic.org)
  • Doctors evaluate bronchiectasis with a chest x-ray, breathing tests, sputum culture or computed tomography (CT) scan. (copdsupport.ie)
  • The most popular test for bronchiectasis diagnosis is a chest computed tomography (CT) scan because a chest X-ray does not give enough information. (medanta.org)
  • Moreover, your doctor will attempt to determine the origin of the bronchiectasis based on your history and the results of the physical examination after the chest CT scan has verified the condition. (medanta.org)
  • Computed tomography (CT) of the chest revealed bibasilar bronchiectasis and prominent peribronchial thickening in right lower and middle lobes, and lingula. (cdc.gov)
  • Bronchiectasis is characterised by excessive neutrophilic inflammation. (ed.ac.uk)
  • Aspiration of gastric acid or food particles into the lungs can lead to inflammation and bronchiectasis, particularly in individuals with conditions like gastroesophageal reflux disease (GERD). (ayurvedguru.com)
  • Transbronchial biopsy showed chronic peribronchial inflammation and fibrosis compatible with airway disease/bronchiectasis. (cdc.gov)
  • Symptoms of bronchiectasis commonly include a cough productive of frequent green or yellow sputum lasting months to years. (wikipedia.org)
  • Long-term (chronic) cough with large amounts of foul smelling sputum is the main symptom of bronchiectasis. (medlineplus.gov)
  • Patrick Flume, MD: Could a Persistent Cough be Bronchiectasis? (hcplive.com)
  • Dr Megan Crichton, a postdoctoral researcher at the University of Dundee, UK, who presented the research, said: "One of the main characteristics of bronchiectasis is a productive cough, with almost three quarters of bronchiectasis patients producing sputum daily. (thesynapse.net)
  • Bronchiectasis should be suspected in patients with a chronic cough that produces large amounts of sputum . (amboss.com)
  • A persistent cough that produces large amounts of mucus (sputum) is the most common symptom of bronchiectasis. (ayurvedguru.com)
  • And lastly, our understanding of the etiology of bronchiectasis has also evolved. (reachmd.com)
  • Diagnostic testing is geared toward identifying the underlying etiology, as treatment will be successful only if it treats both the bronchiectasis and any underlying disease process. (bmj.com)
  • Investigate the possible etiology of a patient's bronchiectasis. (medscape.com)
  • Finch S et al (2015) A comprehensive analysis of the impact of Pseudomonas aeruginosa colonisation on prognosis in adult bronchiectasis. (bronchiectasis.com.au)
  • Haworth CS, Foweraker JE, Wilkinson P, Kenyon RF, Bilton (2014) Inhaled colistin in patients with bronchiectasis and chronic Pseudomonas aeruginosa infection Am J Respir Crit Care Med . (bronchiectasis.com.au)
  • If your lungs cannot move enough oxygen into your body, bronchiectasis can lead to serious illness, including heart failure. (copdsupport.ie)
  • Bronchiectasis can affect just one section of one of your lungs or many sections of both lungs. (copdsupport.ie)
  • It is the largest study of airway clearance use for bronchiectasis to date. (rtmagazine.com)
  • Physicians have many therapy options to offer to bronchiectasis patients requiring regular airway clearance. (afflovest.com)
  • Overall, the use of airway clearance is a safe way to treat and manage bronchiectasis in most patients by improving expectoration, lung function measurements and the ability to enjoy life. (afflovest.com)
  • This topic covers the diagnosis and management of noncystic fibrosis bronchiectasis in children, adolescents, and adults. (bmj.com)
  • Metersky ML. The initial evaluation of adults with bronchiectasis. (univalle.edu.co)
  • While the prevalence of bronchiectasis has increased globally in past decades, it remains one of the most underdiagnosed and neglected lung diseases in children and adults worldwide. (telethonkids.org.au)
  • The majority of adults with bronchiectasis will have symptoms in childhood and childhood bronchiectasis may be reversible with early diagnosis and effective treatment in childhood. (telethonkids.org.au)
  • Acquired bronchiectasis occurs in adults and older children. (copdsupport.ie)
  • While noteworthy for its specific findings, this study is widely cited as a reason cystic fibrosis treatment strategies cannot be universally applied to all types of bronchiectasis. (thoracic.org)
  • The overarching objective of this study is to improve the health outcomes of children with bronchiectasis. (telethonkids.org.au)
  • This study aimed to (i) identify health service costs of hospitalizations and (ii) factors associated with these costs in children admitted to an Australian paediatric hospital following an acute exacerbation of their bronchiectasis. (asthmafoundation.org.nz)
  • Patients can periodically experience an acute worsening of symptoms, referred to as an acute exacerbation of bronchiectasis , which commonly requires antibiotic treatment. (amboss.com)
  • People with bronchiectasis may have bad breath from active infection. (wikipedia.org)
  • Bronchiectasis and non-tuberculous mycobacterial pulmonary infection. (medscape.com)
  • Bronchiectasis patients are often given antibiotics for infection and bronchodilator medicines to open passages. (copdsupport.ie)
  • Vitamin D deficiency is common in bronchiectasis and correlates with markers of disease severity. (medscape.com)
  • Vitamin-D deficiency is associated with chronic bacterial colonisation and disease severity in bronchiectasis. (medscape.com)
  • Congenital bronchiectasis usually affects infants and children. (copdsupport.ie)
  • Primary immunodeficiency (PID) hypogammaglobulinemia Common Variable Immunodeficiency (CVID) bronchiectasis Recurring pneumonia. (univalle.edu.co)
  • [ 1 ] Cylindrical bronchiectasis involves diffuse mucosal edema, with resultant bronchi that are dilated but have straight, regular outlines that end squarely and abruptly (see the image below). (medscape.com)
  • Cylindrical bronchiectasis with signet-ring appearance. (medscape.com)
  • On thoracic radiographs, cylindrical bronchiectasis, generalized disease, and right cranial lung lobe involvement were most common. (avma.org)
  • Massive hemoptysis is a rare complication of bronchiectasis and requires surgery or pulmonary artery embolization. (amboss.com)
  • Dr Critchton and her colleagues recorded the sputum colour in 13,484 out of 19,324 patients who regularly coughed up sputum and who were enrolled in the pan-European bronchiectasis registry, EMBARC. (thesynapse.net)
  • The EMBARC (European Multicentre Bronchiectasis Audit and Research Collaboration) registry is a prospective, pan-European observational study of patients with bronchiectasis. (ersjournals.com)
  • Towards functional correlates of microbiota and immune phenotype in rheumatoid arthritis and bronchiectasis. (hra.nhs.uk)
  • Certain autoimmune conditions, such as rheumatoid arthritis and Sjögren's syndrome, can be associated with bronchiectasis. (ayurvedguru.com)
  • This fact sheet describes bronchiectasis, including how it affects breathing, what causes it, and how it's diagnosed and treated. (nih.gov)
  • As we celebrate International Women's Day, we turn our attention to how bronchiectasis uniquely affects women and the impact that has on gender equality in healthcare and what can be done. (copdfoundation.org)
  • So in summary, non-CF bronchiectasis affects many more than we initially thought. (reachmd.com)
  • Cystic fibrosis is a genetic disorder that affects the production of mucus and can lead to the development of bronchiectasis. (ayurvedguru.com)
  • Bacterial colonization in patients with bronchiectasis: microbiological pattern and risk factors. (medscape.com)
  • Participants will be asked to donate a stool sample a sputum sample (bronchiectasis patients only) and a blood sample which will be used to study the gut microbiome, lung microbiome and inflammatory white blood cells respectively as well as to complete a short questionnaire giving information about their general health and diet. (hra.nhs.uk)
  • The study examined data from a registry of adult bronchiectasis patients' self-reported outcomes collected by RespirTech, a Philips company. (rtmagazine.com)
  • This data repository is now the largest bronchiectasis research registry in the world. (rtmagazine.com)
  • In patients with suspected bronchiectasis, diagnosis is confirmed using imaging studies, preferably a HRCT scan. (amboss.com)
  • Despite paediatric bronchiectasis being recognized increasingly worldwide, prior reports of hospitalization costs for bronchiectasis in children are lacking. (asthmafoundation.org.nz)
  • This type of therapy is used to treat many different types of lung diseases in which mucus buildup is a concern, including bronchiectasis. (afflovest.com)
  • Bronchiectasis may result from a number of infectious and acquired causes, including measles, pneumonia, tuberculosis, immune system problems, as well as the genetic disorder cystic fibrosis. (wikipedia.org)
  • He complained of recurring pneumonia associated with widespread bronchiectasis since he was 18 years old. (univalle.edu.co)
  • What we now know is that non-CF bronchiectasis is not a rare disease. (reachmd.com)
  • Almost 10 years later, considerable scientific advances have been made in both the treatment and the evaluation and diagnosis of this disease, and the original guidelines have been updated to include the latest therapies available for bronchiectasis. (archbronconeumol.org)
  • Bronchiectasis is a chronic lung disease that impairs quality of life and reduces life expectancy. (telethonkids.org.au)
  • Lung damage caused by bronchiectasis often worsens over the course of the disease. (afflovest.com)
  • Many undergoing such therapies report better quality of life, and since techniques can be tailored to patients' needs and are suitable for both children and the elderly, ACT shows promise as part of a bronchiectasis treatment protocol regardless of a patient's age, lifestyle or disease stage. (afflovest.com)
  • There must be more information available for women to understand how bronchiectasis and other lung diseases affect them in a unique way. (copdfoundation.org)
  • A key element of creating a gender equal world is working to eliminate any gender bias in the diagnosis, treatment and management of chronic lung diseases including bronchiectasis. (copdfoundation.org)
  • Patients with RA are also at a higher risk of developing certain lung diseases and so this study will also look at the gut/lung microbiome and white blood cell phenotype in a group of patients who have both RA and bronchiectasis. (hra.nhs.uk)
  • A group of 51 patients diagnosed with interstitial lung diseases, bronchiectasis, asthma and scoliosis were studied. (who.int)