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BromosuccinimidePeriodicals as TopicAccess to InformationJournal Impact FactorPublishingBibliometricsPeer Review, Research2-Hydroxy-5-nitrobenzyl BromideSuccinimidesTryptophanCeriumAmino AcidsChemistryMethylene BlueQuinolonesSpectrophotometryAntipsychotic AgentsSpectrophotometry, UltravioletPiperazinesTransition TemperatureChalonesBromineChalconesSpores, ProtozoanMarketingResearch ReportFoundationsDieteticsJournalism, MedicalPublicationsPatents as Topicgamma-Aminobutyric AcidInventionsIntellectual PropertyHistory, 18th CenturyBiotechnologyHistory, 17th CenturyMethanolvon Willebrand Factorvon Willebrand DiseasesWaterCommerceTaxesPrescription FeesPhilatelyGreat BritainGermanyMedicine, ArabicAntimitotic AgentsCell ProliferationMicrotubulesTubulinForamen Ovale, PatentCell Line, Tumor
Bromosuccinimide
A brominating agent that replaces hydrogen atoms in benzylic or allylic positions. It is used in the oxidation of secondary alcohols to ketones and in controlled low-energy brominations. (From Miall's Dictionary of Chemistry, 5th ed; Hawley's Condensed Chemical Dictionary, 12th ed,).
Periodicals as Topic
A publication issued at stated, more or less regular, intervals.
Access to Information
Individual's rights to obtain and use information collected or generated by others.
Journal Impact Factor
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
Publishing
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
Bibliometrics
The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)
Peer Review, Research
The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.
2-Hydroxy-5-nitrobenzyl Bromide
A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as Koshland's reagent.
Succinimides
A subclass of IMIDES with the general structure of pyrrolidinedione. They are prepared by the distillation of ammonium succinate. They are sweet-tasting compounds that are used as chemical intermediates and plant growth stimulants.
Tryptophan
An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.
Cerium
An element of the rare earth family of metals. It has the atomic symbol Ce, atomic number 58, and atomic weight 140.12. Cerium is a malleable metal used in industrial applications.
Amino Acids
Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.
Chemistry
A basic science concerned with the composition, structure, and properties of matter; and the reactions that occur between substances and the associated energy exchange.
Methylene Blue
A compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene blue is used as a bacteriologic stain and as an indicator. It inhibits GUANYLATE CYCLASE, and has been used to treat cyanide poisoning and to lower levels of METHEMOGLOBIN.
Quinolones
A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.
Spectrophotometry
The art or process of comparing photometrically the relative intensities of the light in different parts of the spectrum.
Antipsychotic Agents
Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
Spectrophotometry, Ultraviolet
Determination of the spectra of ultraviolet absorption by specific molecules in gases or liquids, for example Cl2, SO2, NO2, CS2, ozone, mercury vapor, and various unsaturated compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Piperazines
Transition Temperature
The temperature at which a substance changes from one state or conformation of matter to another.
Chalones
Peptides that inhibit mitosis (ANTIMITOTICS). During the 1960's the term referred to crude extracts that inhibited cell proliferation; the activity was later attributed to PYROGLUTAMATE type oligopeptides.
Bromine
A halogen with the atomic symbol Br, atomic number 36, and atomic weight 79.904. It is a volatile reddish-brown liquid that gives off suffocating vapors, is corrosive to the skin, and may cause severe gastroenteritis if ingested.
Chalcones
Compounds based on CHALCONE. They are important intermediates in the formation of FLAVONOIDS.
Spores, Protozoan
A vegetative stage in the life cycle of sporozoan protozoa. It is characteristic of members of the phyla APICOMPLEXA and MICROSPORIDIA.
Marketing
Activity involved in transfer of goods from producer to consumer or in the exchange of services.
Research Report
Detailed account or statement or formal record of data resulting from empirical inquiry.
Foundations
Organizations established by endowments with provision for future maintenance.
Dietetics
The application of nutritional principles to regulation of the diet and feeding persons or groups of persons.
Journalism, Medical
The collection, writing, and editing of current interest material on topics related to biomedicine for presentation through the mass media, including newspapers, magazines, radio, or television, usually for a public audience such as health care consumers.
Publications
Copies of a work or document distributed to the public by sale, rental, lease, or lending. (From ALA Glossary of Library and Information Science, 1983, p181)
Patents as Topic
Exclusive legal rights or privileges applied to inventions, plants, etc.
gamma-Aminobutyric Acid
The most common inhibitory neurotransmitter in the central nervous system.
Inventions
A novel composition, device, or process, independently conceived de novo or derived from a pre-existing model.
Intellectual Property
Property, such as patents, trademarks, and copyright, that results from creative effort. The Patent and Copyright Clause (Art. 1, Sec. 8, cl. 8) of the United States Constitution provides for promoting the progress of science and useful arts by securing for limited times to authors and inventors, the exclusive right to their respective writings and discoveries. (From Black's Law Dictionary, 5th ed, p1014)
History, 18th Century
Time period from 1701 through 1800 of the common era.
Biotechnology
Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.
History, 17th Century
Time period from 1601 through 1700 of the common era.
Methanol
A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
von Willebrand Factor
A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.
von Willebrand Diseases
Group of hemorrhagic disorders in which the VON WILLEBRAND FACTOR is either quantitatively or qualitatively abnormal. They are usually inherited as an autosomal dominant trait though rare kindreds are autosomal recessive. Symptoms vary depending on severity and disease type but may include prolonged bleeding time, deficiency of factor VIII, and impaired platelet adhesion.
Water
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Commerce
The interchange of goods or commodities, especially on a large scale, between different countries or between populations within the same country. It includes trade (the buying, selling, or exchanging of commodities, whether wholesale or retail) and business (the purchase and sale of goods to make a profit). (From Random House Unabridged Dictionary, 2d ed, p411, p2005 & p283)
Taxes
Governmental levies on property, inheritance, gifts, etc.
Prescription Fees
The charge levied on the consumer for drugs or therapy prescribed under written order of a physician or other health professional.
Philately
Study of stamps or postal markings. It usually refers to the design and commemorative aspects of the stamp.
Great Britain
Germany
Medicine, Arabic
Traditional Arabic methods used in medicine in the ARAB WORLD.
Antimitotic Agents
Agents that arrest cells in MITOSIS, most notably TUBULIN MODULATORS.
Cell Proliferation
All of the processes involved in increasing CELL NUMBER including CELL DIVISION.
Microtubules
Slender, cylindrical filaments found in the cytoskeleton of plant and animal cells. They are composed of the protein TUBULIN and are influenced by TUBULIN MODULATORS.
Tubulin
A microtubule subunit protein found in large quantities in mammalian brain. It has also been isolated from SPERM FLAGELLUM; CILIA; and other sources. Structurally, the protein is a dimer with a molecular weight of approximately 120,000 and a sedimentation coefficient of 5.8S. It binds to COLCHICINE; VINCRISTINE; and VINBLASTINE.
Foramen Ovale, Patent
A condition in which the FORAMEN OVALE in the ATRIAL SEPTUM fails to close shortly after birth. This results in abnormal communications between the two upper chambers of the heart. An isolated patent ovale foramen without other structural heart defects is usually of no hemodynamic significance.
Cell Line, Tumor
A cell line derived from cultured tumor cells.

Localization and environment of tryptophans in soluble and membrane-bound states of a pore-forming toxin from Staphylococcus aureus. (1/116)

The location and environment of tryptophans in the soluble and membrane-bound forms of Staphylococcus aureus alpha-toxin were monitored using intrinsic tryptophan fluorescence. Fluorescence quenching of the toxin monomer in solution indicated varying degrees of tryptophan burial within the protein interior. N-Bromosuccinimide readily abolished 80% of the fluorescence in solution. The residual fluorescence of the modified toxin showed a blue-shifted emission maximum, a longer fluorescence lifetime as compared to the unmodified and membrane-bound alpha-toxin, and a 5- to 6-nm red edge excitation shift, all indicating a restricted tryptophan environment and deeply buried tryptophans. In the membrane-bound form, the fluorescence of alpha-toxin was quenched by iodide, indicating a conformational change leading to exposure of some tryptophans. A shorter average lifetime of tryptophans in the membrane-bound alpha-toxin as compared to the native toxin supported the conclusions based on iodide quenching of the membrane-bound toxin. Fluorescence quenching of membrane-bound alpha-toxin using brominated and spin-labeled fatty acids showed no quenching of fluorescence using brominated lipids. However, significant quenching was observed using 5- and 12-doxyl stearic acids. An average depth calculation using the parallax method indicated that the doxyl-quenchable tryptophans are located at an average depth of 10 A from the center of the bilayer close to the membrane interface. This was found to be in striking agreement with the recently described structure of the membrane-bound form of alpha-toxin.  (+info)

Characterization of exo-(1,4)-alpha glucan lyase from red alga Gracilaria chorda. Activation, inactivation and the kinetic properties of the enzyme. (2/116)

Exo-(1,4)-alpha glucan lyase (GLase) was purified from a red alga Gracilaria chorda. The enzyme was activated 1.3-fold in the presence of Ca(2+) and Cl(-) ions. The ions also stabilized the enzyme increasing the temperature of its maximum activity from 45 degrees C to 50 degrees C. GLase was inactivated by chemical modification with carbodiimide and a carboxyl group of the enzyme was shown essential to the lyase activity. A tryptophanyl residue(s) was also shown to be important for the activity and was probably involved in substrate binding. K(m) values of the enzyme were 2.3 mM for maltose, 0.4 mM for maltotriose and 0.1 mM for maltooligosaccharides of degree of polymerization (dp) 4-7, and the k(0) values for the oligosaccharides were similar (42-53 s(-1)). The analysis of these kinetic parameters showed that the enzyme has four subsites to accommodate oligosaccharides. The subsite map of GLase was unique, since subsite 1 and subsite 2 have large positive and small negative affinities, respectively. The subsite map of this type has not been found in other enzymes with exo-action on alpha-1,4-glucan. The K(m) and k(0) values for the polysaccharides were lower (0.03 mM) and higher (60-100 s(-1)), respectively, suggesting the presence of another affinity site specific to the polysaccharides.  (+info)

Energy transfer between terbium (III) and cobalt (II) in thermolysin: a new class of metal--metal distance probes. (3/116)

The visible fluorescence of terbium(III) when bound to a calcium binding site of thermolysin is greatly enhanced with an excitation maximum at 280 nm but substitution of cobalt(II) for zinc at the active site decreases the intensity by 89.5%. Treatment with N-bromosuccinimide quenches enzyme tryptophan and Tb(III) fluorescence to a similar extent and suggests the operation of tryptophan vector Tb(III) vector Co(II) energy relay system in the enzyme. Dipoledipole radiationless energy transfer between the Tb(III) donor and the Co(II) acceptor can account for this quenching. The inherent characteristics of the metal pair limits the value of the orientation factor, K2, of the Forster equation, thereby reducing uncertainties in distance measurements by energy transfer compared with other systems. A quantum yield of 0.51 yields a value of R0, the distance for 50% energy transfer, of 19.6 A, and a distance, R, between Tb(III) and Co(II) of 13.7 A, a value identical to that measured for the distance between the active site zinc atom and calcium atom number 1 by x-ray analysis in native thermolysin crystals. The limits of confidence of this measurement are discussed. Energy transfer between two different metal atom sites of a protein provides a new class of probes to measure intramolecular distances of biological macromolecules in solution.  (+info)

Purification and characterization of beta-1,3-xylanase from a marine bacterium, Vibrio sp. XY-214. (4/116)

beta-1,3-Xylanase was purified to gel electrophoretic homogeneity and 83-fold from a cell-free culture fluid of Vibrio sp. XY-214 by ammonium sulfate precipitation and successive chromatographies. The enzyme had a pl of 3.6 and a molecular mass of 52 kDa. The enzyme had the highest level of activity at pH 7.0 and 37 degrees C. The enzyme activity was completely inhibited by Cu2+, Hg2+, and N-bromosuccinimide. The enzyme hydrolyzed beta-1,3-xylan to produce mainly xylotriose and xylobiose but did not act on xylobiose, p-nitrophenyl-beta-D-xyloside, beta-1,4-xylan, beta-1,3-glucan, or carboxymethyl cellulose.  (+info)

Structure-function studies of tryptophan mutants of equinatoxin II, a sea anemone pore-forming protein. (5/116)

Equinatoxin II (EqtII) is a eukaryotic cytolytic toxin that avidly creates pores in natural and model lipid membranes. It contains five tryptophan residues in three different regions of the molecule. In order to study its interaction with the lipid membranes, three tryptophan mutants, EqtII Trp(45), EqtII Trp(116/117) and EqtII Trp(149), were prepared in an Escherichia coli expression system [here, the tryptophan mutants are classified according to the position of the remaining tryptophan residue(s) in each mutated protein]. They all possess a single intrinsic fluorescent centre. All mutants were less haemolytically active than the wild-type, although the mechanism of erythrocyte damage was the same. EqtII Trp(116/117) resembles the wild-type in terms of its secondary structure content, as determined from Fourier-transform infrared (FTIR) spectra and its fluorescent properties. Tryptophans at these two positions are buried within the hydrophobic interior of the protein, and are transferred to the lipid phase during the interaction with the lipid membrane. The secondary structure of the other two mutants, EqtII Trp(45) and EqtII Trp(149), was altered to a certain extent. EqtII Trp(149) was the most dissimilar from the wild-type, displaying a higher content of random-coil structure. It also retained the lowest number of nitrogen-bound protons after exchange with (2)H(2)O, which might indicate a reduced compactness of the molecule. Tryptophans in EqtII Trp(45) and EqtII Trp(149) were more exposed to water, and also remained as such in the membrane-bound form.  (+info)

Location of tryptophan residues in free and membrane bound Escherichia coli alpha-hemolysin and their role on the lytic membrane properties. (6/116)

alpha-hemolysin (HlyA) is an extracellular protein toxin secreted by Escherichia coli that acts at the level of plasma cell membranes of target eukaryotic cells. Previous studies showed that toxin binding to the bilayers occurs in at least two ways, a reversible adsorption and an irreversible insertion. Studies of HlyA insertion into bilayers formed from phosphatidylcholine show that insertion is accompanied by an increase in the protein intrinsic fluorescence. In order to better define structural parameters of the membrane-bound form, the location of tryptophan residues was studied by means of quenchers of their intrinsic fluorescence located at 7, 12 and 16 positions of the acyl chain of phosphatidylcholine. The quenching was progressively weaker suggesting an interfacial location of the Trp. In parallel, HlyA was subjected to oxidation with N-bromosuccinimide to study the role of Trp residues exposed to aqueous media in its structure-function relationship. In the folded toxin molecule, a single residue was susceptible to oxidation with NBS, whereas incubation with LUV of the toxin prior modification prevents its oxidation, suggesting that Trp residue(s) are directly involved in toxin binding and insertion. Finally, the modification of residues exposed to solvent resulted in a complete impairment of the lytic activity. It was concluded that the modification-sensitive Trp residues are essential for the structure and function of native HlyA. These results are consistent with the model proposed by Soloaga et al. (Mol. Microbiol. 31 (1999) 1013-1024) according to which HlyA is bound to a single monolayer through a number of amphipathic instead of inserted transmembrane helices.  (+info)

Involvement of arginine and tryptophan residues in catalytic activity of glutaryl 7-aminocephalosporanic acid acylase from Pseudomonas sp. strain GK16. (7/116)

The glutaryl 7-aminocephalosporanic acid (GL-7-ACA) acylase from Pseudomonas sp. strain GK16 is an (alphabeta)2 heterotetramer of two non-identical subunits that are cleaved autoproteolytically from an enzymatically inactive precursor polypeptide. The newly formed N-terminal serine of the beta subunit plays an essential role as a nucleophile in enzyme activity. Chemical modification studies on the recombinant enzyme purified from Escherichia coli revealed the involvement of a single arginine and tryptophan residue, per alphabeta heterodimer of the enzyme, in the catalytic activity of the enzyme. Glutaric acid, 7-aminocephalosporanic acid (7-ACA) (competitive inhibitors) and GL-7-ACA (substrate) could not protect the enzyme against phenylglyoxal-mediated inactivation, whereas except for glutaric acid protection was observed in case of N-bromosuccinimide-mediated inactivation of the enzyme. Kinetic parameters of partially inactivated enzyme samples suggested that while arginine is involved in catalysis, tryptophan is involved in substrate binding.  (+info)

Tryptophan environment in adenosine deaminase. I. Enzyme modification with N-bromosuccinimide in the presence of adenosine and EHNA analogues. (8/116)

Adenosine deaminase from bovine cerebral hemisphere (white and gray matter) and spleen was treated with N-bromosuccinimide, a reagent known to oxidize selectively tryptophan residues in proteins. Spectrally observable tryptophan modification was accompanied by enzyme inactivation. Tsow graphics revealed that two Trps are essential for the activity of enzyme from both tissues. Enzyme inhibitors and substrate analogues, derivatives of erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) and adenosine, were able to protect Trp against modification, and this effect correlated in general with the enzyme activity protection. In the presence of adenosine deaza analogues (the noninhibitor tubercidin among them) only two Trps were modified in the fully inactivated enzyme. In the presence of EHNA and its deaza analogues, full inactivation of the enzyme was accompanied by the modification of four Trps. The obtained data confirm the previous hypothesis about the presence on the enzyme of different binding sites for adenosine and EHNA derivatives that are responsible for the different effects on the enzyme conformation elicited by the corresponding derivatives. Moreover, these data allow us to suggest that Trp residues, still unidentified by X-ray analysis, are essential for the functioning of the enzyme.  (+info)

N-Bromosuccinimide | 128-08-5N-Bromosuccinimide | 128-08-5
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CAS No.128-08-5,N-Bromosuccinimide SuppliersCAS No.128-08-5,N-Bromosuccinimide Suppliers
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L K RamachandranL K Ramachandran
The essential role of tyrosine residue(s) of cardiotoxin II in the biological activity of the toxin was evaluated using N-bromosuccinimide. N-bromosuccinimide effected oxidation of the tyrosine residues in cardiotoxin II with enhancement in absorbance at 260 nm. The influence of various solvent media such as acetate-formate buffer (pH 4.0), 0.01 N H2SO4 (pH 2.0) and Tris-HCl buffer (pH 8.5) on oxidation of tyrosine residues was exa mined. In comparison with 0.01 N H2S O4, acetate-formate buffer could prevent secondary oxidations as revealed by lower consumption of oxidant, N-bromosuccinimide, to achieve oxidation. In Tris-HCl buffer oxidation of tyrosine did not take place effectively. N-iodo-succinimide caused only limited oxidation as evident from minor increase in absorbance at 260 nm. N-chlorosuccinimide was completely ineffective. Oxidation of cardiotoxin II with 3.75 equivalents of N-bromosuccinimide tyrosine residue led to complete loss of lethal activity. However, the derivative retained ...
https://www.ias.ac.in/listing/bibliography/jbsc/L._K._Ramachandran
Gentaur Molecular :Nacala \ N‐Bromosuccinimide \ 05823-22Gentaur Molecular :Nacala \ N‐Bromosuccinimide \ 05823-22
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Aripiprazole | Methylene Blue | N-bromosuccinimide | SpectrophotometryAripiprazole | Methylene Blue | N-bromosuccinimide | Spectrophotometry
A simple, sensitive and rapid spectrophotometric method has been developed for the determination of aripiprazole in pharmaceutical formulations. The proposed method is based on the..
http://www.ijpsonline.com/articles/spectrophotometric-estimation-of-aripiprazole-in-tablets.html?view=mobile
Kinetics and Mechanism of Micellar Catalyzed Oxidation of Dextrose by N-Bromosuccinimide in H2SO4 MediumKinetics and Mechanism of Micellar Catalyzed Oxidation of Dextrose by N-Bromosuccinimide in H2SO4 Medium
International Journal of Carbohydrate Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of carbohydrate chemistry.
https://www.hindawi.com/journals/ijcc/2014/783521/
Reaktionen von ( E)-Cycloocten mit N-Bromsuccinimid in Gegenwart von Wasser oder Methanol | SpringerLinkReaktionen von ( E)-Cycloocten mit N-Bromsuccinimid in Gegenwart von Wasser oder Methanol | SpringerLink
The reactions of ( E)-cyclooctene with N-bromosuccinimide in the presence of water or methanol are described. Major products of the hydroxybromination are trans-4-bromocyclooctanol as a product of...
https://link.springer.com/article/10.1007/BF00903754
Formation of bromohydrins from alkenes using water and NBSFormation of bromohydrins from alkenes using water and NBS
Description: Alkenes treated with N-bromosuccinimde (NBS) and water will form bromohydrins. [private_ReactionGuide] Notes: The reaction is Markovnikoff selective and provides the trans-product. NBS stands for N-bromosuccinimide, it looks like this: Examples: Notes: Note how in examples 1
https://staging.masterorganicchemistry.com/reaction-guide/formation-of-bromohydrins-from-alkenes-using-water-and-nbs/
Vicinal bromofluoroalkanes: their regioselective formation and their conversion to fluoro olefinsVicinal bromofluoroalkanes: their regioselective formation and their conversion to fluoro olefins
Reaction of alkenes with N-bromosuccinimide and Et3N.3HF produces vic-bromofluoroalkanes in high yields. As long as the addn. to the C:C bond is sterically unhindered, Br and F get attached with very high regioselectivity, the latter occupying the more substituted, carbocation-stabilizing position. 2-Fluoro-1-alkenes give 1-bromo-2,2-difluoroalkanes. The Br may be removed by base-promoted dehydrofluorination to afford fluoro olefins, or by redn. with Bu3SnH, leading to mono- or difluoroalkanes. [on SciFinder (R)] Suga, Hiroaki; Hamatani, Takeshi; Guggisberg, Yves; Schlosser, Manfred
https://infoscience.epfl.ch/record/81597
Epigenetic changes behind chronic kidney diseaseEpigenetic changes behind chronic kidney disease
Washington - Researchers have found, in a genome-wide survey, significant differences in the pattern of chemical modifications on DNA, which affect gene ex
https://www.indiavision.com/scitech/epigenetic-changes-behind-chronic-kidney-disease/465642/
Chiral N,N′-dioxide-Sc(NTf2)3 complex-catalyzed asymmetric bromoamination of chalones with N-bromosuccinimide as both bromine...Chiral N,N′-dioxide-Sc(NTf2)3 complex-catalyzed asymmetric bromoamination of chalones with N-bromosuccinimide as both bromine...
The catalytic asymmetric bromoamination of chalcones with N-bromosuccinimide as both bromine and amide source was realized by using a chiral N,N′-dioxide-Sc(NTf2)3 complex as an efficient catalyst. The corresponding chiral bromoamination products were obtained in high yields with high dr and good ee values (
http://pubs.rsc.org/en/content/articlelanding/2017/cc/c7cc00470b
Global N-Bromosuccinimide Market Research Report 2017 - RnR Market ResearchGlobal N-Bromosuccinimide Market Research Report 2017 - RnR Market Research
Global N-Bromosuccinimide Market Research Report 2017 is a market research report available at US $2900 for a Single User PDF License from RnR Market Research Reports Library.
http://www.rnrmarketresearch.com/global-n-bromosuccinimide-market-research-report-2017-market-report.html
N-Bromosuccinimide and Lithium Bromide: An Efficient Combination for the Dibromination of Carbon-Carbon Unsaturated BondsN-Bromosuccinimide and Lithium Bromide: An Efficient Combination for the Dibromination of Carbon-Carbon Unsaturated Bonds
see article for more examples. Abstract. Unsaturated compounds such as alkenes, alkynes, allenes, and methylenecyclopropanes (MCPs) can be dibrominated within minutes by NBS and lithium bromide in THF at room temperature in good to excellent yields under mild conditions.. ...
http://www.organic-chemistry.org/abstracts/literature/456.shtm
The subunit structure of jack-bean urease | Biochemical JournalThe subunit structure of jack-bean urease | Biochemical Journal
1. Urease of specific activity 160-180 Sumner units/g. (Sumner, 1951) was purified from jack-bean meal. The preparation was pure on the basis of polyacryl-amide-gel electrophoresis and N-terminal studies. 2. By using both the 1-fluoro-2,4-dinitrobenzene method and the phenyl isothiocyanate method a single N-terminal methionine residue was found. 3. A single C-terminal sequence -Tyr-Leu-Phe was found by studies with carboxypeptidase A, carboxypeptidase B and hydrazinolysis. 4. N-Bromosuccinimide cleavage showed that five unique tryptophan sequences were present: Trp-Ala, Trp-Glu, Trp-Gly, Trp-Met and Trp-Arg. 5. Polyacrylamide-gel electrophoresis in sodium dodecyl sulphate showed that urease had a subunit molecular weight of 76000. 6. The yield of N- and C-terminal amino acids, the number of tryptic peptides and tryptophan sequences and the above polyacrylamide-gel electrophoretic measurement all suggest that urease contains a single structural subunit of molecular weight 75000.. ...
http://www.biochemj.org/content/113/4/669
Azatriptycene.Azatriptycene.
N-bromosuccinimide or dibromodimethylhydantoin on (2) [4] and subsequent treatment with pyridine (yield c a . 1 5 04). Accordingly, the so-called pentatetraene has the constitution (3) of tetra-(P,P-diphenylvinyl)ethylene, in agreement with its N M R spectrum, molecular-weight measurements, and other results. (1) (CaH5)2C=C=C=C=C(C6H5)2 (2) (CsH5)2C==CH CH ~CH-C(CaH5)z ~ (C6Hc),C=CH-LH~--CH=C(CsHc)2 (3) (CaHc)2C-CH--C (CsH,);C-CH CHy-C(CsH5)z II -C CH -C(CaH& So far, all attempts to prepare genuine pentatetraenes have resulted in ring-closure to yield derivatives of indene [ I ] or dimerisation with or without partial hydrogenation. Received, April 29tI1, 1963 [Z 492/325 IE] German version: Ang-w. Chem. 75,452 (1963). [I] Communication No. X V on Cumulenes; Communication No. X I V : R . Kuhn and B. Schulz, Angew. Chem. 74,292 (1962); Angew. Chem. internat. Edit. I , 211 (1962). [2] F. Rohlmann and K . Kieslich, Abh. braunschweig. wiss. Ges. I 9 5 7 , I X . 147. [3] G. Mavin, Thkse Ingenieur ...
https://www.docme.ru/doc/1904239/azatriptycene
TWO SELECTIVE SPECTROPHOTOMETRY METHODS FOR THE DETERMINATION OF THIORIDAZINE HYDROCHLORIDE IN TABLETS AND IN BIOLOGICAL FLUIDSTWO SELECTIVE SPECTROPHOTOMETRY METHODS FOR THE DETERMINATION OF THIORIDAZINE HYDROCHLORIDE IN TABLETS AND IN BIOLOGICAL FLUIDS
EL-DIDAMONY, A. M e MOUSTAFA, M. A. TWO SELECTIVE SPECTROPHOTOMETRY METHODS FOR THE DETERMINATION OF THIORIDAZINE HYDROCHLORIDE IN TABLETS AND IN BIOLOGICAL FLUIDS. J. Chil. Chem. Soc. [online]. 2012, vol.57, n.1, pp.983-988. ISSN 0717-9707. http://dx.doi.org/10.4067/S0717-97072012000100006.. Two simple, rapid and selective spectrophotometric methods have been developed for the analysis of the psychoactive drug thioridazine HCl (TRH) in tablets and in biological fluids. The first method is based on the oxidation of TRH by a known excess of N- bromosuccinimide (NBS), followed by the determination of unreacted oxidants by measuring the decrease in absorbance of two different dyes; amaranth (AM) and methylene blue (MB) at a suitable λmax 520 and 660 nm, respectively. Beer-Lambert plots showed good correlation in the concentration ranges of 0.8-4.8 and 0.8-5.6 µg/ml for AM and MB methods, respectively. The second method is based upon the formation of an ion-pair complexes (1: 1) with the acidic ...
http://www.scielo.cl/scielo.php?script=sci_abstract&pid=S0717-97072012000100006&lng=pt&nrm=iso&tlng=en
Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation | Biochemical JournalTryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation | Biochemical Journal
Myeloperoxidase, released by activated phagocytes, forms reactive oxidants by catalysing the reaction of halide and pseudo-halide ions with H2O2. These oxidants have been linked to tissue damage in a range of inflammatory diseases. With physiological levels of halide and pseudo-halide ions, similar amounts of HOCl (hypochlorous acid) and HOSCN (hypothiocyanous acid) are produced by myeloperoxidase. Although the importance of HOSCN in initiating cellular damage via thiol oxidation is becoming increasingly recognized, there are limited data on the reactions of HOSCN with other targets. In the present study, the products of the reaction of HOSCN with proteins has been studied. With albumin, thiols are oxidized preferentially forming unstable sulfenyl thiocyanate derivatives, as evidenced by the reversible incorporation of 14C from HOS14CN. On consumption of the HSA (human serum albumin) free thiol group, the formation of stable 14C-containing products and oxidation of tryptophan residues are ...
http://www.biochemj.org/content/416/3/441
Tryptophan residue is essential for immunoreactivity of a diagnostically relevant peptide epitope of A. fumigatus -...Tryptophan residue is essential for immunoreactivity of a diagnostically relevant peptide epitope of A. fumigatus -...
The role of tryptophan (Trp17) in immunoreactivity of P1, the diagnostically relevant peptide from a major allergen/antigen of Aspergillus fumigatus, was evaluated by chemically modifying tryptophanyl residue of P1. In BIAcore kinetic studies, unmodified P1 showed a 100-fold higher binding with ABPA (Allergic Bronchopulmonary Aspergillosis) patients IgG [KD (equilibrium dissociation constant) = 2.74 e−8 ± 0.13 M] than the controls IgG (KD = 2.97 e−6 ± 0.14 M), whereas chemically-modified P1 showed similar binding [KD patients IgG = 3.25 e−7± 0.16 M, KD controls IgG = 3.86 e−7 ± 0.19 M] indicating loss of specific immunoreactivity of P1 on tryptophan modification. Modified P1 showed loss of specific binding to IgE and IgG antibodies of ABPA patients in ELISA (Enzyme-Linked Immunosorbent Assay). The study infers that tryptophan residue (Trp17)) is essential for immunoreactivity of P1. ...
http://repository.ias.ac.in/100945/
A guide to avoid method bias of chromium(III, VI) chemiluminescence determination by luminol-hydrogen peroxide reaction....A guide to avoid method bias of chromium(III, VI) chemiluminescence determination by luminol-hydrogen peroxide reaction....
EN] Cr(III) and/or Cr(VI) determinations based on light emission produced by luminol oxidation by hydrogen peroxide in basic aqueous solution catalyzed by Cr(III) were studied in order to diagnose and/or avoid method bias. The calibration step was optimized, and the usefulness of the method for speciating chromium was tested. The use of the standard addition method in the linear interval concentration range made it possible to diagnose the accuracy of the method for real samples. Good results were obtained for several real water samples containing chromium at different concentrations. The proposed protocol made the method traceable with an appropriate certified reference material and with the reference method ...
https://riunet.upv.es/handle/10251/116485?show=full
Compounds and possessed relatively lowCompounds and possessed relatively low
Chemistry Synthesis of test compounds is outlined in Schemes Scheme 1, Scheme 2, Scheme 3, Scheme 4. Compounds 3-5 were synthesized as described in Scheme 1. Palladium-catalyzed carbonylation of triflates derived from phenols 19a and b in the presence of methanol afforded methyl esters 20a and b. Bromination of 20a and b with N-bromosuccinimide in the presence of benzoyl perbromide provided 21a and b, respectively. Lithium aluminum hydride (LAH) reduction of 4-bromo-2-methyl benzoic acid 22 gave an alcohol 23. Palladium-catalyzed carbonylation of 23 in the presence of methanol provided a methyl benzoate 24, bromination of which afforded a benzylbromide 21c. Alkylation of a phenol intermediate 25 with benzyl halides 21a-c in the presence of potassium carbonate afforded 26a-c, respectively. Alkaline hydrolysis of methyl esters 26a-c gave 3-5, respectively. Synthesis of 6 is described in Scheme 2. Esterification of the benzoic acid 27 with diazomethane followed by LAH reduction gave a benzyl ...
http://phenpropionate.com/index.php?g=Wap&m=Article&a=detail&id=1596
N-acetylimidazole CAS:2466-76-4 - Zhejiang Chenxin Technology CO.,LTD. - ecplaza.netN-acetylimidazole CAS:2466-76-4 - Zhejiang Chenxin Technology CO.,LTD. - ecplaza.net
N-acetylimidazole CAS:2466-76-4 C5H6N2O 110.12 A white crystalline powder content more than 98% application:Used for pharmaceutical intermediates 25 kg/cardboard barrels
https://www.ecplaza.net/products/n-acetylimidazole-cas2466-76-4_4064156
Takahashi Taxol total synthesis - WikipediaTakahashi Taxol total synthesis - Wikipedia
The Takahashi Taxol total synthesis published by Takashi Takahashi in 2006 is one of several successful methods in taxol total synthesis. The method starts from geraniol and differs from the other 6 published methods that it is a formal synthesis (the final product is baccatin III which lacks the amide tail found in taxol itself) and that it is racemic (the product baccatin III is optically inactive). A key feature of the published procedure is that several synthetic steps (construction of rings A, B and C) were performed in an automated synthesizer on a scale up to 300 gram and that purification steps were also automated. Ring A was synthesised starting from geraniol 1 and involved acylation (acetic anhydride, DMAP, Et3N) to 2, epoxidation (N-bromosuccinimide, tBuOH/H2O then triethylamine) to 3, radical cyclisation (titanocene dichloride, manganese, triethylborane, 2,6-lutidine) to 4, alcohol protection (ethyl vinyl ether, camphorsulfonic acid) to 5, alcohol deprotection (NaOH, MeOH/THF/H2O) to ...
https://en.wikipedia.org/wiki/Takahashi_Taxol_total_synthesis
Study reveals a mechanism for mate selection - Healthcanal.com : Healthcanal.comStudy reveals a mechanism for mate selection - Healthcanal.com : Healthcanal.com
Simply put, an organism knows that a potential mate is close-by and healthy enough to mate. This mating decision is controlled by a simple chemical switch that converts an incoming pheromone signal into a cellular response, says senior author Stephen Michnick, a Université de Montréal biochemistry professor and Canada Research Chair in Integrative Genomics.. As pheromone signal increases, two enzymes in the cell begin to compete with each other, one adding, the other removing a chemical modification on a protein called Ste5, continues Dr. Michnick, noting that at a critical threshold of pheromone signal, one of the enzymes overwhelms the others capacity to modify Ste5, triggering a sudden, switch-like cascade of chemical messages to be delivered to the cell to say its time to mate. The findings were made in collaboration with physicist Peter Swain, of McGill University and the University of Edinburgh, and his postdoctoral fellow Vahid Shahrezaei, now a lecturer at Imperial College ...
https://www.healthcanal.com/female-reproductive/7179-study-reveals-a-mechanism-for-mate-selection.html
Algorithms | Free Full-Text | Algorithm for the Analysis of Tryptophan Fluorescence Spectra and Their Correlation with Protein...Algorithms | Free Full-Text | Algorithm for the Analysis of Tryptophan Fluorescence Spectra and Their Correlation with Protein...
The fluorescence properties of tryptophan residues are sensitive to the microenvironment of fluorophores in proteins. Therefore, fluorescence characteristics are widely used to study structural transitions in proteins. However, the decoding of the structural information from spectroscopic data is challenging. Here we present a review of approaches developed for the decomposition of multi-component protein tryptophan fluorescence spectra and correlation of these spectral parameters with protein structural properties.
http://www.mdpi.com/1999-4893/2/3/1155
Process optimization for production and purification of a thermostable, organic solvent tolerant lipase from Acinetobacter sp....Process optimization for production and purification of a thermostable, organic solvent tolerant lipase from Acinetobacter sp....
REFERENCES. 1 Maruyama T, Nakajima M, Ichikawa S, Nabetani H, Furusaki S, Seki M. Oil-water interfacial activation of lipase for interesterification of triglyceride and fatty acid. J Am Oil Chem Soc. 2000;77:1121-1127. [ Links ] 2 Verma ML, Azmi W, Kanwar SS. Microbial lipases: at the interface of aqueous and non-aqueous media. A review. Acta Microbiol Immunol Hung. 2008;55:265-294. [ Links ] 3 Belfrage P, Fredrikson G, Stralfors P, Tornquist H. In: Borgstrom B, Brockman HL, eds. Lipases. Amsterdam: Elsevier Science; 1984:365-416. [ Links ] 4 Akoh CC, Sellappan S, Fomuso LB, Yankah G V.V. Enzymatic synthesis of structured lipids. In: Kuo TM, Gardner HW, eds. Lipid Biotechnology. New York, USA: Marcel Dekker;2002:433-460.5. [ Links ] 5 Saxena RK, Sheoran A, Giri B, Davidson SW. Purification strategies for microbial lipases. J Microbiol Methods. 2003;52:1-18. [ Links ] 6 Koops BC, Verheij HM, Slotboom AJ, Egmond MR. Effect of chemical modification on the activity of lipases in organic solvents. ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000300647&lang=en
Pseudocholinesterase Deficiency - Treatment, Symptoms, Causes, PrognosisPseudocholinesterase Deficiency - Treatment, Symptoms, Causes, Prognosis
Pseudocholinesterase deficiency is a rare genetic condition where the affected individual has increased sensitivity to several anesthetic agents. The use of these drugs may leave some of the muscles paralyzed
http://ihealthzoom.com/pseudocholinesterase-deficiency/
Pseudocholinesterase: a protein with functions unrelated to its name | Biochemical Society Transactions | Portland PressPseudocholinesterase: a protein with functions unrelated to its name | Biochemical Society Transactions | Portland Press
K.M. KUTTY, V. ANNAPURNA, V. PRABHAKARAN; Pseudocholinesterase: a protein with functions unrelated to its name. Biochem Soc Trans 1 June 1989; 17 (3): 555-556. doi: https://doi.org/10.1042/bst0170555. Download citation file:. ...
https://portlandpress.com/biochemsoctrans/article-abstract/17/3/555/77799/Pseudocholinesterase-a-protein-with-functions
Neuromuscular · Part OneNeuromuscular · Part One
IV onset in 30s to 1 minute, lasting 2-3 minutes, with offset typically within 10 minutes. Offset occurs due to dissociation of drug out of NMJ into plasma, as a concentration gradient is established by drug breakdown in plasma. Prolonged duration in patients with pseudocholinesterase deficiency. IM onset in 2-3 minues ...
http://www.partone.lifeinthefastlane.com/depolarising_nmbs.html
Jadwin Dam Safety Modification StudyJadwin Dam Safety Modification Study
The official website of the Philadelphia District, U.S. Army Corps of Engineers. For website corrections, write to [email protected]
https://www.nap.usace.army.mil/jadwin/
NBS Create | NBSNBS Create | NBS
With NBS Create you can produce professional outline, performance and full specifications with architecture, structural, building services and landscape content more efficiently. NBS Create is an essential tool for BIM projects.
https://www.thenbs.com/services/our-tools/nbs-create
Vinca alkaloid - WikipediaVinca alkaloid - Wikipedia
The Madagascan periwinkle Catharanthus roseus L. is the source for a number of important natural products,[1] including catharanthine and vindoline[2] and the vinca alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine[3] and vincristine,[4] all of which can be obtained from the plant.[5][6][7][8] The newer semi-synthetic chemotherapeutic agent vinorelbine is used in the treatment of non-small-cell lung cancer[7][9] and is not known to occur naturally. However, it can be prepared either from vindoline and catharanthine[7][10] or from leurosine,[11] in both cases by synthesis of anhydrovinblastine, which can be considered as the key intermediate for the synthesis of vinorelbine.[7] The leurosine pathway uses the Nugent-RajanBabu reagent in a highly chemoselective de-oxygenation of leurosine.[12][11] Anhydrovinblastine is then reacted sequentially with N-bromosuccinimide and trifluoroacetic acid followed by silver tetrafluoroborate to yield vinorelbine.[10] ...
https://en.wikipedia.org/wiki/Vinca_alkaloids
4-Nitrobenzyl alcohol 619-73-8, China 4-Nitrobenzyl alcohol 619-73-8 Manufacturers, China 4-Nitrobenzyl alcohol 619-73-8...4-Nitrobenzyl alcohol 619-73-8, China 4-Nitrobenzyl alcohol 619-73-8 Manufacturers, China 4-Nitrobenzyl alcohol 619-73-8...
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http://chemnet.com/ChinaSuppliers/14820/4-Nitrobenzyl-alcohol--1670036.html
5-(4-Nitrobenzyl)-[1,3,4]thiadiazol-2-ylamine 247225-84-9 H-NMR | C-NMR Spectral Analysis NMR Spectrum5-(4-Nitrobenzyl)-[1,3,4]thiadiazol-2-ylamine 247225-84-9 H-NMR | C-NMR Spectral Analysis NMR Spectrum
5-(4-Nitrobenzyl)-[1,3,4]thiadiazol-2-ylamine 247225-84-9 NMR spectrum, 5-(4-Nitrobenzyl)-[1,3,4]thiadiazol-2-ylamine H-NMR spectral analysis, 5-(4-Nitrobenzyl)-[1,3,4]thiadiazol-2-ylamine C-NMR spectral analysis ect.
http://www.molbase.com/en/hnmr_247225-84-9-moldata-72959.html
Serum Atypical Pseudocholinesterase and Genetic Factors in Leprosy | The BMJSerum Atypical Pseudocholinesterase and Genetic Factors in Leprosy | The BMJ
Thank you for your interest in spreading the word about The BMJ.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
http://www.bmj.com/content/3/5823/390/submit-a-rapid-response
Design, synthesis and biological characterization of thiazolidin-4-one derivatives as promising inhibitors of Toxoplasma gondii...Design, synthesis and biological characterization of thiazolidin-4-one derivatives as promising inhibitors of Toxoplasma gondii...
TY - JOUR. T1 - Design, synthesis and biological characterization of thiazolidin-4-one derivatives as promising inhibitors of Toxoplasma gondii. AU - DAscenzio, Melissa. AU - Bizzarri, Bruna. AU - De Monte, Celeste. AU - Carradori, Simone. AU - Bolasco, Adriana. AU - Secci, Daniela. AU - Rivanera, Daniela. AU - Faulhaber, Nathan. AU - Bordón, Claudia. AU - Jones-Brando, Lorraine. PY - 2014/8/19. Y1 - 2014/8/19. N2 - We designed and synthesized a large number of novel thiazolidin-4-one derivatives for the evaluation of their anti-Toxoplasma gondii activity. This scaffold was functionalized at the N1-hydrazine portion with aliphatic, cycloaliphatic and (hetero)aromatic moieties. Then, a benzyl pendant was introduced at the lactamic NH of the core nucleus to evaluate the influence of this chemical modification on biological activity. The compounds were subjected to several in vitro assays to assess their anti-parasitic efficacy, cytotoxicity on fibroblasts, inhibition of tachyzoite ...
https://jhu.pure.elsevier.com/en/publications/design-synthesis-and-biological-characterization-of-thiazolidin-4-5
Weight: Succinylcholine requirement and pseudocholinesterase activity?<...Weight: Succinylcholine requirement and pseudocholinesterase activity?<...
TY - JOUR. T1 - Weight. T2 - Succinylcholine requirement and pseudocholinesterase activity?. AU - Bentley, J. B.. AU - Borel, J. D.. AU - Vaughan, R. W.. AU - Gandolfi, A. J.. PY - 1981/1/1. Y1 - 1981/1/1. UR - http://www.scopus.com/inward/record.url?scp=0019790277&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0019790277&partnerID=8YFLogxK. M3 - Article. AN - SCOPUS:0019790277. VL - 55. SP - A213. JO - Anesthesiology. JF - Anesthesiology. SN - 0003-3022. IS - 3 Suppl.. ER - ...
https://arizona.pure.elsevier.com/en/publications/weight-succinylcholine-requirement-and-pseudocholinesterase-activ
Kinetics of the methylene blue oxidation by cerium(iv) in sulphuric acid solutions<...Kinetics of the methylene blue oxidation by cerium(iv) in sulphuric acid solutions<...
TY - JOUR. T1 - Kinetics of the methylene blue oxidation by cerium(iv) in sulphuric acid solutions. AU - Katafias, A.. AU - Kita, P.. AU - Wrzeszcz, G.. AU - Mills, A.. PY - 2007/2. Y1 - 2007/2. N2 - The oxidation of methylene blue (MB+) by cerium(IV) was studied in 0.1-5 M H2SO4. The reaction proceeds via MB radical (MB2+•) formed by one electron transfer to the oxidant. The radical is observed spectrophotometrically by a very intense absorbance at λmax = 526 nm and by the e.p.r signal at g = 2.000. The kinetics of the fast radical formation are two orders of magnitude slower than its decomposition, which were examined using a stopped-flow method at 298 K under pseudo-first order conditions. The rate laws for the both steps were determined and a likely mechanism reported.. AB - The oxidation of methylene blue (MB+) by cerium(IV) was studied in 0.1-5 M H2SO4. The reaction proceeds via MB radical (MB2+•) formed by one electron transfer to the oxidant. The radical is observed ...
https://pureportal.strath.ac.uk/en/publications/kinetics-of-the-methylene-blue-oxidation-by-ceriumiv-in-sulphuric
PQR | N-(4-{hydroxy[(4-nitrobenzyl)oxy]phosphoryl}butanoyl)glycinePQR | N-(4-{hydroxy[(4-nitrobenzyl)oxy]phosphoryl}butanoyl)glycine
You are viewing an interactive 3D depiction of the molecule n-(4-{hydroxy[(4-nitrobenzyl)oxy]phosphoryl}butanoyl)glycine (C13H17N2O8P) from the PQR.
http://pqr.pitt.edu/mol/LNMNPGKCSJFAGN-UHFFFAOYSA-N
TryptophanTryptophan
Buy Tryptophan Supplements online at VitaminExpress and save. Guaranteed Quality. Free Shipping. Fast Delivery. Order Tryptophan now.
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TryptophanTryptophan
There are many individuals who still do not have a good grasp with regards to the difference between 5-HTP and Tryptophan. Because of this fact, there is a great need to reiterate and explain further the set of differences between the two. We could not fully understand how they work and the good … [Read more...] ...
https://vitamins.vitanetonline.com/index.php/tag/tryptophan/
Nutrineal® PD4, komb.Nutrineal® PD4, komb.
Peritonealdialysevæske. 1 l indeholder 951 mg alanin, 1.071 mg L-arginin, 184 mg calciumchlorid, 510 mg glycin, 714 mg histidin, 850 mg isoleucin, 1.020 mg leucin, 955 mg lysinhydrochlorid, 51 mg magnesiumchlorid, 850 mg methionin, 5.380 mg natriumchlorid, 4.480 mg natriumlactat, 570 mg phenylalanin, 595 mg prolin, 510 mg serin, 646 mg threonin, 270 mg tryptophan, 300 mg tyrosin og 1.393 mg valin. ...
https://pro.medicin.dk/Medicin/Praeparater/1911
Trimeresurus flavoviridis GPLI-I protein Summary Report | CureHunterTrimeresurus flavoviridis GPLI-I protein Summary Report | CureHunter
Trimeresurus flavoviridis GPLI-I protein: serum protein that inhibits phospholipase A2; isolated from Trimeresurus flavoviridis; amino acid sequence in first source; GenBank AB003472 and AB003473
http://www.curehunter.com/public/keywordSummaryC109601-Trimeresurus-flavoviridis-GPLI-I-protein.do
Direct linkDirect link
The large neutral amino acids tyrosine and tryptophan are precursors of the neurotransmitters dopamine and serotonin and their availability in the brain may influence neurotransmission. Disturbed neurotransmitter systems, such as the dopaminergic, noradrenergic and serotoninergic systems are implicated in the pathogenesis of neuropsychiatric disorders, including schizophrenia, bipolar disorder, autism and attention deficit hyperactivity disorder (ADHD).. The primary aim of this study is to outline the findings/evidence from different investigations in vitro, concerning aberrant amino acid (tyrosine, tryptophan and alanine) transport in fibroblasts obtained from patients with schizophrenia and their relatives, bipolar-I disorder, autism and ADHD disorders.. The outlines of the findings presented in this study provide evidence that amino acids, tyrosine and tryptophan are strongly involved in schizophrenia, bipolar disorder, autism and ADHD.. ...
http://oru.diva-portal.org/smash/record.jsf?pid=diva2%3A896242
4-Chloro-2-nitrobenzyl chloride, 98%, ACROS Organics™ 1g 4-Chloro-2-nitrobenzyl chloride, 98%, ACROS Organics™ | Fisher...4-Chloro-2-nitrobenzyl chloride, 98%, ACROS Organics™ 1g 4-Chloro-2-nitrobenzyl chloride, 98%, ACROS Organics™ | Fisher...
4-Chloro-2-nitrobenzyl chloride, 98%, ACROS Organics™ 1g 4-Chloro-2-nitrobenzyl chloride, 98%, ACROS Organics™ Benzyl chlorides
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Foods To Eat To Enhance Your Dreams - disinformationFoods To Eat To Enhance Your Dreams - disinformation
A double-blind study revealed that participants who took a daily 250mg B6 supplement reported a significant increase in dream content - as measured in dream vividness, bizarreness, emotionality and color. One of the roles of vitamin B6 is to convert the essential amino acid tryptophan into serotonin and niacin. This helps the body regulate appetite, sleep patterns and mood. Low levels of tryptophan are also linked with poor dream recall.. When youre ready to begin the dream-intensity challenge, take your vitamin B6 supplement and then fuel the fire with plenty of tryptophan-rich foods such as:. ...
http://disinfo.com/2012/09/foods-to-eat-to-enhance-your-dreams/
Pills Lenuksin: reviews, instructions for use, description, analogs pricePills Lenuksin: reviews, instructions for use, description, analogs price
Psychotropic substances, the list of which is extensive enough, should be taken only when prescribed by specialists and strictly under his control.. medicament Lenuksin prohibited administered together with MAO inhibitors, as this may contribute to the development of serotonin syndrome.It should also be noted that the reception of this means young people (under the age of 24 ex-years) with mental disorders and depression raises the emergence of suicidal ideation and suicidal behavior.. When using medication with lithium and tryptophan are cases enhance the effect of the first drug Joint medication with Hypericum perforatum leads to an increase in side effects.. Simultaneous use of antidepressants with indirect anticoagulants and other agents that affect blood clotting, can contribute to a violation of the process.In such cases, at the end of treatment requires regular monitoring of the patient and the condition of his blood.. Patients who take said medication with serotonergic agents, ...
https://healthtipsing.com/en/pages/69026
Simple and Rapid Spectrophotometric Determination of Titanium on Etched Aluminum Foils - pdf descargarSimple and Rapid Spectrophotometric Determination of Titanium on Etched Aluminum Foils - pdf descargar
Simple and Rapid Spectrophotometric Determination of Titanium on Etched Aluminum Foils. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
http://libros.duhnnae.com/2017/jun8/149821247689-Simple-and-Rapid-Spectrophotometric-Determination-of-Titanium-on-Etched-Aluminum-Foils.php
2-Nitrobenzyl chloride | C7H6ClNO2 - PubChem2-Nitrobenzyl chloride | C7H6ClNO2 - PubChem
2-Nitrobenzyl chloride | C7H6ClNO2 | CID 11921 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
https://pubchem.ncbi.nlm.nih.gov/compound/2-Nitrobenzyl_chloride
RCSB PDB for 1F0FRCSB PDB for 1F0F
1F0F: Role of the hinge region and the tryptophan residue in the synthetic antimicrobial peptides, cecropin A(1-8)-magainin 2(1-12) and its analogues, on their antibiotic activities and structures.
http://www.rcsb.org/pdb/explore/biologyAndChemistry.do?structureId=1F0F
ErythrosineErythrosine
"N-Bromosuccinimide". ACS Omega. 3 (10): 12868-12877. doi:10.1021/acsomega.8b02320. PMC 6644467. PMID 31458011. Cantor S (April ...
https://en.wikipedia.org/wiki/Erythrosine
Wohl-Ziegler brominationWohl-Ziegler bromination
Once all N-bromosuccinimide (which is denser than the solvent) has been converted to succinimide (which floats on top) the ... In a typical setup, a stoichiometric amount of N-bromosuccinimide solution and a small quantity of initiator are added to a ... Best yields are achieved with N-bromosuccinimide in carbon tetrachloride solvent. Several reviews have been published. ... 1948-10-01). "Brominations with N-Bromosuccinimide and Related Compounds. The Wohl-Ziegler Reaction". Chemical Reviews. 43 (2 ...
https://en.wikipedia.org/wiki/Wohl–Ziegler_bromination
CarbanionCarbanion
N-bromosuccinimide and diiodine), and proton donors. A carbanion is one of several reactive intermediates in organic chemistry ...
https://en.wikipedia.org/wiki/Carbanion
N-ChlorosuccinimideN-Chlorosuccinimide
N-bromosuccinimide (NBS), the bromine analog of N-chlorosuccinimide. Other N-chloro compounds that are commercially available ...
https://en.wikipedia.org/wiki/N-Chlorosuccinimide
FostedilFostedil
Bromination of this compound with N-bromosuccinimide produces bromomethyl intermediate. The synthesis of fostedil concludes ...
https://en.wikipedia.org/wiki/Fostedil
CyanamideCyanamide
... adds itself in the presence of N-bromosuccinimide to olefinic double bonds. The addition product is converted by ...
https://en.wikipedia.org/wiki/Cyanamide
PhotochlorinationPhotochlorination
N-bromosuccinimide is also suitable as a brominating agent. The quantum yield of photobromination is usually much lower than ...
https://en.wikipedia.org/wiki/Photochlorination
SuccinimideSuccinimide
Succinic anhydride N-Hydroxysuccinimide N-Bromosuccinimide International Union of Pure and Applied Chemistry (2014). ...
https://en.wikipedia.org/wiki/Succinimide
1,2-Dibromoethylene1,2-Dibromoethylene
Alternately, halogenation of this kind could also be achieved through the use of two equivalents of N-bromosuccinimide and ... Shao, L.-X.; Shi, M. (2006). "N-Bromosuccinimide and Lithium Bromide: An Efficient Combination for the Dibromination of Carbon- ... lithium bromide (LiBr). N-Bromosuccinimide provides Br+ as an electrophile, which is followed by Br− from LiBr. "Chapter 9: ...
https://en.wikipedia.org/wiki/1,2-Dibromoethylene
CanthaxanthinCanthaxanthin
Petracek, F. J.; Zechmeister, L. (1956). "Reaction of beta-carotene with N-bromosuccinimide: the formation and conversions of ...
https://en.wikipedia.org/wiki/Canthaxanthin
BromochlorobenzeneBromochlorobenzene
... silane using N-bromosuccinimide From 4-chlorophenol using triphenylphosphine dibromide or phenylphosphorus tetrachloride ... "Carbon-silicon bond cleavage of organotrialkoxysilanes and organosilatranes with m-chloroperbenzoic acid and N-bromosuccinimide ...
https://en.wikipedia.org/wiki/Bromochlorobenzene
SPANphosSPANphos
The resultant spirocycle is halogenated with N-bromosuccinimide followed by lithium-bromide exchange using n-BuLi. Treatment of ...
https://en.wikipedia.org/wiki/SPANphos
Benzo(c)fluoreneBenzo(c)fluorene
... using the reagent N-bromosuccinimide. This substance is dehydrobrominated to 2H-inden-1-one (3) using the reagent triethylamine ...
https://en.wikipedia.org/wiki/Benzo(c)fluorene
IndoleIndole
Simple oxidants such as N-bromosuccinimide will selectively oxidize indole 1 to oxindole (4 and 5). Only the C2-C3 pi bond of ...
https://en.wikipedia.org/wiki/Indole
Hofmann rearrangementHofmann rearrangement
Sodium hypochlorite, lead tetraacetate, N-bromosuccinimide, and (bis(trifluoroacetoxy)iodo)benzene can effect a Hofmann ...
https://en.wikipedia.org/wiki/Hofmann_rearrangement
TolueneToluene
For example, N-bromosuccinimide (NBS) heated with toluene in the presence of AIBN leads to benzyl bromide. The same conversion ...
https://en.wikipedia.org/wiki/Toluene
2-Furonitrile2-Furonitrile
... for the instance oxidative dehydration of furfural with ammonia salts using hypervalent iodine reagents or n-bromosuccinimide. ...
https://en.wikipedia.org/wiki/2-Furonitrile
VinorelbineVinorelbine
Anhydrovinblastine is then reacted sequentially with N-bromosuccinimide and trifluoroacetic acid followed by silver ...
https://en.wikipedia.org/wiki/Vinorelbine
Chemistry of ascorbic acidChemistry of ascorbic acid
Another alternative uses N-bromosuccinimide (NBS) as the oxidizing agent, in the presence of potassium iodide and starch. The ...
https://en.wikipedia.org/wiki/Chemistry_of_ascorbic_acid
Bis(cyclopentadienyl)titanium(III) chlorideBis(cyclopentadienyl)titanium(III) chloride
Anhydrovinblastine is then reacted sequentially with N-bromosuccinimide and trifluoroacetic acid followed by silver ...
https://en.wikipedia.org/wiki/Bis(cyclopentadienyl)titanium(III)_chloride
In-MethylcyclophaneIn-Methylcyclophane
Next the methyl substituents are functionalized with bromine groups by the photochemical reaction with N-bromosuccinimide or ...
https://en.wikipedia.org/wiki/In-Methylcyclophane
N-IodosuccinimideN-Iodosuccinimide
NIS is the iodine analog of N-chlorosuccinimide (NCS) and N-bromosuccinimide (NBS) which are used for similar applications. "N- ...
https://en.wikipedia.org/wiki/N-Iodosuccinimide
L-Photo-leucineL-Photo-leucine
Then, N-bromosuccinimide, CCl4 and 48% HBr are added and the mixture is stirred at 55 °C for 4 hours. The solvent and free ...
https://en.wikipedia.org/wiki/L-Photo-leucine
Alkenylaluminium compoundsAlkenylaluminium compounds
8) Treatment of alkenylaluminates with halogen electrophiles such as N-bromosuccinimide (NBS) and iodine leads to the formation ... of N-bromosuccinimide while keeping the temperature below -15°. The reaction mixture was gradually warmed to room temperature ...
https://en.wikipedia.org/wiki/Alkenylaluminium_compounds
BromineBromine
... such as N-bromosuccinimide. The principal reactions for organobromides include dehydrobromination, Grignard reactions, ...
https://en.wikipedia.org/wiki/Bromine
Stilbene photocyclizationStilbene photocyclization
After benzylic bromization with N-bromosuccinimide, transformation to the phosphonium salt, and a Wittig reaction with ...
https://en.wikipedia.org/wiki/Stilbene_photocyclization
Ramberg-Bäcklund reactionRamberg-Bäcklund reaction
... be synthesized through the treatment of sulfides with halogen electrophiles such as N-chlorosuccinimide or N-bromosuccinimide.[ ...
https://en.wikipedia.org/wiki/Ramberg–Bäcklund_reaction
FluoxymesteroneFluoxymesterone
N-bromosuccinimide (NBS), is determined by the formation of a bromonium intermediate; the electrophilic bromonium cation ...
https://en.wikipedia.org/wiki/Fluoxymesterone
FormazanFormazan
Among the various oxidants used are mercuric oxide, nitric acid, isoamyl nitrite, N-bromo succinimide, potassium permanganate, ...
https://en.wikipedia.org/wiki/Formazan
ImideImide
Examples that are useful in organic synthesis are N-chlorosuccinimide and N-bromosuccinimide, which respectively serve as ...
https://en.wikipedia.org/wiki/Imide
N-Bromosuccinimide - WikipediaN-Bromosuccinimide - Wikipedia
N-Bromosuccinimide or NBS is a chemical reagent used in radical substitution, electrophilic addition, and electrophilic ... Dauben, H. J., Jr; McCoy, L. L. (1959). "N-Bromosuccinimide. I. Allylic Bromination, a General Survey of Reaction Variables". J ... Mitchell, R. H.; Lai, Y. H.; Williams, R. V. (1979). "N-Bromosuccinimide-dimethylformamide: a mild, selective nuclear ... Usage of N-bromosuccinimide in organic syntheses Reactions with NBS. ...
https://en.wikipedia.org/wiki/N-Bromosuccinimide
N-Bromosuccinimide (NBS)N-Bromosuccinimide (NBS)
... is a brominating and oxidizing agent that is used as source for bromine in ... A N-bromosuccinimide-mediated direct synthesis of 2,5-diarylox azoles starting from N-H ketoaziridines proceeds via in situ ... Aryl and heteroaryl boronic acids react with N-iodosuccinimide and N-bromosuccinimide to give the corresponding iodo- and bromo ... A novel electrophilic one-pot reaction of an olefin, a cyanimide, an amine, and N-bromosuccinimide enables the synthesis of a ...
https://www.organic-chemistry.org/chemicals/oxidations/n-bromosuccinimide-nbs.shtm
Kinetics and Mechanism of Micellar Catalyzed Oxidation of Dextrose by N-Bromosuccinimide in H2SO4 MediumKinetics and Mechanism of Micellar Catalyzed Oxidation of Dextrose by N-Bromosuccinimide in H2SO4 Medium
... Minu Singh ... for the oxidation of dextrose by N-bromosuccinimide in the absence and presence of SDS and TX-100 at 40°C. ... Kinetics and mechanism of micellar catalyzed N-bromosuccinimide oxidation of dextrose in H2SO4 medium was investigated under ... The determined stoichiometric ratio was 1 : 1 (dextrose : N-bromosuccinimide). The variation of Hg(OAC)2 and succinimide ( ...
https://www.hindawi.com/journals/ijcc/2014/783521/
Utility of N-Bromosuccinimide for the Titrimetric and Spectrophotometric Determination of Famotidine in Pharmaceutical...Utility of N-Bromosuccinimide for the Titrimetric and Spectrophotometric Determination of Famotidine in Pharmaceutical...
Utility of N-Bromosuccinimide for the Titrimetric and Spectrophotometric Determination of Famotidine in Pharmaceutical ... "Sensitive spectrophotometric method for the determination of H2-receptor antagonists by means of N-bromosuccinimide and p- ...
https://www.hindawi.com/journals/ijac/2011/581372/ref/
CAS No.128-08-5,N-Bromosuccinimide SuppliersCAS No.128-08-5,N-Bromosuccinimide Suppliers
where to buy 128-08-5(N-Bromosuccinimide).Also offer free database of 128-08-5(N-Bromosuccinimide) including MSDS sheet( ... N-Bromosuccinimide Basic information Product Name: N-Bromosuccinimide Synonyms: 2,5-PYRROLIDINEDIONE, 1-BROMO-;1-BROMO-2,5- ... Good quantity N-Bromosuccinimide Basic information Product Name: N-Bromosuccinimide Synonyms: 2,5-PYRROLIDINEDIONE, 1-BROMO-;1- ... Synonyms:?2,5-PYRROLIDINEDIONE,?1-BROMO-;1-BROMO-2,5-PYRROLIDINEDIONE;AKOS?BBS-00004413;bromosuccinimide;BROMOSUCCINIMIDE-N; ...
http://www.lookchem.com/cas-128/128-08-5.html
N-Bromosuccinimide Initiated One-Pot Synthesis of ImidazolineN-Bromosuccinimide Initiated One-Pot Synthesis of Imidazoline
N-Bromosuccinimide Promoted One-Pot Synthesis of Guanidine: Scope and Mechanism. L. Zhou, J. Chen, J. Zhou, Y.-Y. Yeung, Org. ... N-Bromosuccinimide Initiated One-Pot Synthesis of Imidazoline. Ling Zhou, Jing Zhou, Chong Kiat Tan, Jie Chen and Ying-Yeung ... A novel cationic Br initiated one-pot synthesis using olefin, nitrile, amine, and N-bromosuccinimide gives imidazolines in good ...
https://www.organic-chemistry.org/abstracts/lit3/272.shtm
Aripiprazole | Methylene Blue | N-bromosuccinimide | SpectrophotometryAripiprazole | Methylene Blue | N-bromosuccinimide | Spectrophotometry
N-bromosuccinimide (0.0067 mol/l) and methylene blue (0.031 mol/l) were prepared by dissolving 120 mg of N-bromosuccinimide and ... The proposed method is based on the oxidation of drug with N-bromosuccinimide and unreacted N-bromosuccinimide bleaches the ... The proposed method is based on the oxidation of drug with N-bromosuccinimide. Bromine atom of N-bromosuccinimide reacts with ... N-bromosuccinimide (Merck, Mumbai, India) and methylene blue (S.D. Fine Chem, Mumbai, India) were used for the experiment. ...
http://www.ijpsonline.com/articles/spectrophotometric-estimation-of-aripiprazole-in-tablets.html?view=mobile
Molecular Expressions: Science, Optics & You - Olympus MIC-D: Chemical Crystal Movie Gallery - Bromo-Succinimide Movie #1Molecular Expressions: Science, Optics & You - Olympus MIC-D: Chemical Crystal Movie Gallery - Bromo-Succinimide Movie #1
N-bromosuccinimide serves as an oxidizing agent in the synthesis of drugs and hormones. ... Bromo-Succinimide Movie #1. Used by the pharmaceutical and chemical industries as an intermediary, N-bromosuccinimide serves as ... N-bromosuccinimide (NBS) is characterized by a molecular weight of 177.99, a chemical composition of 4 carbon, 4 hydrogen, 1 ... Alternatively, bromosuccinimide is known to biochemists as 1-bromo-2,5-pyrolidinedione or succinibromide. For the laboratory ...
https://micro.magnet.fsu.edu/optics/olympusmicd/galleries/moviegallery/chemicalcrystals/bromosuccinimide/bromosuccinimide1.html
N-Bromosuccinimide | 128-08-5N-Bromosuccinimide | 128-08-5
You can also browse global suppliers,vendor,prices,Price,manufacturers of N-Bromosuccinimide(128-08-5). At last,N- ... Bromosuccinimide(128-08-5) safety, risk, hazard and MSDS, CAS,cas number,Use,cas no may also be you need. ... Visit ChemicalBook To find more N-Bromosuccinimide(128-08-5) information like chemical properties,Structure,melting point, ... N-Bromosuccinimide. CAS No.. 128-08-5. Chemical Name:. N-Bromosuccinimide. Synonyms. NBS;NSC 16;NIBRIN;SUCCINBROMIDE; ...
https://www.chemicalbook.com/ChemicalProductProperty_EN_CB2234049.htm
Chiral N,N′-dioxide-Sc(NTf2)3 complex-catalyzed asymmetric bromoamination of chalones with N-bromosuccinimide as both bromine...Chiral N,N′-dioxide-Sc(NTf2)3 complex-catalyzed asymmetric bromoamination of chalones with N-bromosuccinimide as both bromine...
The catalytic asymmetric bromoamination of chalcones with N-bromosuccinimide as both bromine and amide source was realized by ... Chiral N,N′-dioxide-Sc(NTf2)3 complex-catalyzed asymmetric bromoamination of chalones with N-bromosuccinimide as both bromine ... Chiral N,N′-dioxide-Sc(NTf2)3 complex-catalyzed asymmetric bromoamination of chalones with N-bromosuccinimide as both bromine ... The catalytic asymmetric bromoamination of chalcones with N-bromosuccinimide as both bromine and amide source was realized by ...
http://pubs.rsc.org/en/content/articlelanding/2017/cc/c7cc00470b
N-Bromosuccinimide As An Analytical Reagent For The Spectrophotometric Determination Of Benzimidazole Anthelmintics | AbstractN-Bromosuccinimide As An Analytical Reagent For The Spectrophotometric Determination Of Benzimidazole Anthelmintics | Abstract
N-Bromosuccinimide As An Analytical Reagent For The Spectrophotometric Determination Of Benzimidazole Anthelmintics. Author(s): ... of albendazole mebendazole or fenbendazole based on oxidation of the drug with a known excess of N-bromosuccinimide (NBS) and ...
https://www.ijpsonline.com/abstract/nbromosuccinimide-as-an-analytical-reagent-for-the-spectrophotometric-determination-of-benzimidazole-anthelmintics-1681.html
N-BromosuccinimideN-Bromosuccinimide
Literature References: Prepn: K. Ziegler et al., Ann. 551, 109 (1942). In bromination of olefins: eidem, ibid. 80. The method has been extended to other classes of compds by the use of catalysts: H. Schmid, P. Karrer, Helv. Chim. Acta 29, 573 (1946); H. Schmid, ibid. 1144. In oxidation of aldehydes: Y. F. Cheung, Tetrahedron Lett. 1979, 3809. Review of uses: C. Djerassi, Chem. Rev. 43, 271-317 (1948); R. Filler, ibid. 63, 21-43 (1963); J. S. Pizey, Synthetic Reagents vol. 2 (John Wiley, New York, 1974) pp 1-63. ...
https://www.drugfuture.com/chemdata/N-Bromosuccinimide.html
Global N-Bromosuccinimide Market Research Report 2017 - RnR Market ResearchGlobal N-Bromosuccinimide Market Research Report 2017 - RnR Market Research
Global N-Bromosuccinimide Market Research Report 2017 is a market research report available at US $2900 for a Single User PDF ... 1 N-Bromosuccinimide Market Overview. 1.1 Product Overview and Scope of N-Bromosuccinimide. 1.2 N-Bromosuccinimide Segment by ... Global N-Bromosuccinimide Sales Market Report 2017. United States N-Bromosuccinimide Market Report 2017. Global and Chinese N- ... 5.2 Global N-Bromosuccinimide Revenue and Market Share by Type (2012-2017). 5.3 Global N-Bromosuccinimide Price by Type (2012- ...
http://www.rnrmarketresearch.com/global-n-bromosuccinimide-market-research-report-2017-market-report.html
N -bromosuccinimide-induced aminocyclization-aziridine ring-expansion cascade: An asymmetric and highly stereoselective...N -bromosuccinimide-induced aminocyclization-aziridine ring-expansion cascade: An asymmetric and highly stereoselective...
A novel N-bromosuccinimide induced aminocyclization-aziridine ring expansion cascade is reported. Substituted azepanes were ... N -bromosuccinimide-induced aminocyclization-aziridine ring-expansion cascade: An asymmetric and highly stereoselective ... Zhou, J., Yeung, Y.-Y. (2014-04-18). N -bromosuccinimide-induced aminocyclization-aziridine ring-expansion cascade: An ...
http://scholarbank.nus.edu.sg/handle/10635/94337
Gentaur Molecular :Nacala \ N‐Bromosuccinimide \ 05823-22Gentaur Molecular :Nacala \ N‐Bromosuccinimide \ 05823-22
Bromosuccinimide \ 05823-22 for more molecular products just contact us ... We have also other products like : N‐Bromosuccinimide. Related products : N‐Bromosuccinimide ... 29094599] N-Bromosuccinimide (NBS)-Catalyzed C-H Bond Functionalization: An Annulation of Alkynes with Electron Withdrawing ... 28911632] Determination of urea in milk based on N-bromosuccinimide-dichlorofluorescein postchemiluminescence method.. [ ...
http://www.antibody-antibodies.com/product_det.php?id=2089736&supplier=search&name=N%E2%80%90Bromosuccinimide
CIRCULAR DICHROISM STUDIES ON THE N-BROMOSUCCINIMIDE OXIDATION OF RIBONUCLEASE FROM ASPERGILLUS SAITOI.CIRCULAR DICHROISM STUDIES ON THE N-BROMOSUCCINIMIDE OXIDATION OF RIBONUCLEASE FROM ASPERGILLUS SAITOI.
... Author. OHGI K; IRIE M ... N-BROMOSUCCINIMIDE GROUPE FONCTIONNEL ENZYMOLOGIE BIOCHIMIE Keyword (en). ENZYMES HYDROLASE OXIDATION TRYPTOPHAN ULTRAVIOLET ... 20N-BROMOSUCCINIMIDE%20OXIDATION%20OF%20RIBONUCLEASE%20FROM%20ASPERGILLUS%20SAITOI.&rft.date=1977&rft.aulast=OHGI&rft.aufirst=K ... "CIRCULAR DICHROISM STUDIES ON THE N-BROMOSUCCINIMIDE OXIDATION OF RIBONUCLEASE FROM ASPERGILLUS SAITOI.;s:9:\u0000*\ ...
https://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=PASCAL7850014637
Patent US8268887 - Drug conjugates and methods of use thereof - Google PatentenPatent US8268887 - Drug conjugates and methods of use thereof - Google Patenten
NBS=N-bromosuccinimide. *NHS=N-hydroxysuccinimide. *PBS=phosphate buffered saline. *THF=tetrahydrofuran ...
http://www.google.nl/patents/US8268887
Spectrophotometric determination of pantoprazole sodium in pharmaceuticals using n-bromosuccinimide, methyl orange and indigo...Spectrophotometric determination of pantoprazole sodium in pharmaceuticals using n-bromosuccinimide, methyl orange and indigo...
Spectrophotometric determination of pantoprazole sodium in pharmaceuticals using n-bromosuccinimide, methyl orange and indigo ... in bulk drug and in formulations using N-bromosuccinimide (NBS) and two dyes, methyl orange and indigo carmine, as reagents. ... Spectrophotometric determination of pantoprazole sodium in pharmaceuticals using n-bromosuccinimide, methyl orange and indigo ...
http://eprints.uni-mysore.ac.in/7211/
Erythrosine - WikipediaErythrosine - Wikipedia
"N-Bromosuccinimide". ACS Omega. 3 (10): 12868-12877. doi:10.1021/acsomega.8b02320. PMC 6644467. PMID 31458011. Cantor S (April ...
https://en.wikipedia.org/wiki/Erythrosine
Reaktionen von ( E)-Cycloocten mit N-Bromsuccinimid in Gegenwart von Wasser oder Methanol | SpringerLinkReaktionen von ( E)-Cycloocten mit N-Bromsuccinimid in Gegenwart von Wasser oder Methanol | SpringerLink
... cyclooctene with N-bromosuccinimide in the presence of water or methanol are described. Major products of the ... The reactions of (E)-cyclooctene withN-bromosuccinimide in the presence of water or methanol are described. Major products of ... Reactions of (E)-cyclooctene with N-bromosuccinimide in the presence of water, and methanol, resp. Transanular reactions of ...
https://link.springer.com/article/10.1007/BF00903754
Acta PharmaceuticaActa Pharmaceutica
Rapid titrimetric and spectrophotometric methods for salbutamol sulphate in pharmaceuticals using N-bromosuccinimide. Basavaiah ...
https://www.degruyter.com/view/j/acph.2007.57.issue-1/issue-files/acph.2007.57.issue-1.xml?format=INT
Utility of N-bromosuccinimide as an environmental-friendly reagent for sensitive determination of olanzapine in pharmaceuticals...Utility of N-bromosuccinimide as an environmental-friendly reagent for sensitive determination of olanzapine in pharmaceuticals...
The methods use N-bromosuccinimide [NBS] and two-dyes, namely quinoline yellow and metanil yellow, as reagents. In titrimetry, ... Utility of N-bromosuccinimide as an environmental-friendly reagent for sensitive determination of olanzapine in pharmaceuticals ... Utility of N-bromosuccinimide as an environmental-friendly reagent for sensitive determina ...
https://search.bvsalud.org/gim/resource/en/emr-123027
Patent US6593321 - 2-alkoxyestradiol analogs with antiproliferative and antimitotic activity - Google PatentsPatent US6593321 - 2-alkoxyestradiol analogs with antiproliferative and antimitotic activity - Google Patents
79, p. 2005 (1957)), or to the enol silyl ether followed by reaction with e.g. N-bromosuccinimide (Heathcock, C. H. et al., J. ...
http://www.google.com/patents/US6593321?dq=6,034,652
Journal of Biosciences | Indian Academy of SciencesJournal of Biosciences | Indian Academy of Sciences
... of cardiotoxin II in the biological activity of the toxin was evaluated using N-bromosuccinimide. N-bromosuccinimide effected ... Effect of N-bromosuccinimide-modification of tyrosine side chains of cardiotoxin II of the Indian cobra on biological activity ... Oxidation of cardiotoxin II with 3.75 equivalents of N-bromosuccinimide tyrosine residue led to complete loss of lethal ... N-bromosuccinimide, to achieve oxidation. In Tris-HCl buffer oxidation of tyrosine did not take place effectively. N-iodo- ...
https://www.ias.ac.in/describe/article/jbsc/011/01-04/0287-0297
Direct oxidation of polymeric substrates by multifunctional manganese peroxidase isoenzyme from Pleurotus ostreatus without...Direct oxidation of polymeric substrates by multifunctional manganese peroxidase isoenzyme from Pleurotus ostreatus without...
NBS (N-bromosuccinimide) was purified by recrystallization from water. NBS-MnP2 (VP) was prepared as reported for the chemical ... Blocking of the exposed tryptophan by N-bromosuccinimide inhibited the oxidation of RNase and VA by MnP2 (VP), but its Mn2+- ...
https://portlandpress.com/biochemj/article/386/2/387-393/78721
Simple Accordion with CSS & jQuery by Soh TanakaSimple Accordion with CSS & jQuery by Soh Tanaka
6. N-Bromosuccinimide was purchased from Aldrich Chemical Company, Inc. , and used without purification; the purity of the ... N-bromosuccinimide (11.8 g, 66 mmol) (Note 6) at 0°C. After 15 min, the bath is removed, and stirring is continued at room ... The combination of N-bromosuccinimide, which is a source of electropositive bromine, and Et3N·3HF is a very convenient reagent ... N-Bromosuccinimide: Succinimide, N-bromo- (8); 2,5-Pyrrolidinedione, 1-bromo- (9); (128-08-5) ...
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cphE - Cyanophycinase precursor - Pseudomonas anguilliseptica - cphE gene & proteincphE - Cyanophycinase precursor - Pseudomonas anguilliseptica - cphE gene & protein
Inhibited by N-Bromo-succinimide.1 Publication. Manual assertion based on experiment ini ...
https://www.uniprot.org/uniprot/Q8KQN8
100-43-6 - 4-Vinylpyridine, 95%, stab. with 80 to 150ppm hydroquinone - L13316 - Alfa Aesar100-43-6 - 4-Vinylpyridine, 95%, stab. with 80 to 150ppm hydroquinone - L13316 - Alfa Aesar
In the presence of NaOEt, thiols are protected as their S-2-(4-pyridyl)ethyl thioethers: J. Org. Chem., 51, 4914 (1986). Cleavage can be effected by methylation-hydrolysis: Tetrahedron Lett ., 25, 1223 (1984). Compare also 4-(2-Hydroxyethyl)-pyridine, L13780. Hofman, A. H.; van Ekenstein, G. O. R. A.; Woortman, A. J.; ten Brinke, G.; Loos, K. Poly(4-vinylpyridine)-block-poly(N-acryloylpiperidine) diblock copolymers: synthesis, self-assembly and interaction. Polym. Chem. 2015, 6 (39), 7015-7026.. Grochowicz, M.; Szajnecki, Ł.; Gawdzik, B. 4-Vinylpyridine-Trimethylolpropane Trimethacrylate Composite Polymer Particles and Their Application as Adsorbents. Adsorpt. Sci. Technol. 2015, 33 (6-8), 609-616.. ...
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OxidationBromination using N-bromosucciChemSynthesisTryptophanReagentReactionZhangTyrosineBromineBrominationsSodium dodecylDyesCompoundsReactionsDeterminationRatioModificationChemicalWaterMarketTreatmentTitleActivities
Oxidation7
  • Kinetics and mechanism of micellar catalyzed N-bromosuccinimide oxidation of dextrose in H 2 SO 4 medium was investigated under pseudo-first-order condition temperature of 40°C. The results of the reactions studied over a wide range of experimental conditions show that NBS shows a first order dependence, fractional order, on dextrose and negative fractional order dependence on sulfuric acid. (hindawi.com)
  • The proposed method is based on the oxidation of drug with N -bromosuccinimide and unreacted N -bromosuccinimide bleaches the blue color of methylene blue and is measured at 663 nm. (ijpsonline.com)
  • N-bromosuccinimide effected oxidation of the tyrosine residues in cardiotoxin II with enhancement in absorbance at 260 nm. (ias.ac.in)
  • In comparison with 0.01 N H 2 S O 4 , acetate-formate buffer could prevent secondary oxidations as revealed by lower consumption of oxidant, N-bromosuccinimide, to achieve oxidation. (ias.ac.in)
  • Oxidation of cardiotoxin II with 3.75 equivalents of N-bromosuccinimide tyrosine residue led to complete loss of lethal activity. (ias.ac.in)
  • Blocking of the exposed tryptophan by N -bromosuccinimide inhibited the oxidation of RNase and VA by MnP2 (VP), but its Mn 2+ -oxidizing activity was retained, suggesting that Trp-170 exposed on an enzyme surface is a substrate-binding site both for VA and the polymeric substrates. (portlandpress.com)
  • The site to which the G-2 MAb bound was partially destroyed by sodium dodecyl sulfate and was resistant to oxidation with N-bromosuccinimide. (asm.org)
Bromination using N-bromosucci2
  • 5""""""", 2"""""""']hexadecathiophene (4) by regioselective bromination using N-bromosuccinimide and regioselective lithiation using lithiumdiisopropylamide in ethylbenzene/THF/heptane followed by reaction with trimethyl-stannylchloride and subsequent palladium catalysed Stille coupling. (dtu.dk)
  • Chiral bromosilanes have been prepared from prochiral dihydrosilanes by bromination using N-bromosuccinimide. (thefreedictionary.com)
Chem2
  • How May We Serve You UIV CHEM N-Bromosuccinimide 128-08-5 in stock We can Supply HPLC\HMMR\MS report for you ,pls feel free to contact us! (lookchem.com)
  • N-bromosuccinimide (Merck, Mumbai, India) and methylene blue (S.D. Fine Chem, Mumbai, India) were used for the experiment. (ijpsonline.com)
Synthesis5
  • The use of N -bromosuccinimide enables a metal-free one-pot strategy for the synthesis of pharmaceutically important α-amino ketones from readily available benzylic secondary alcohols and amines. (organic-chemistry.org)
  • A novel cationic Br initiated one-pot synthesis using olefin, nitrile, amine, and N -bromosuccinimide gives imidazolines in good yields. (organic-chemistry.org)
  • Used by the pharmaceutical and chemical industries as an intermediary, N-bromosuccinimide serves as an oxidizing agent in the synthesis of drugs and hormones. (fsu.edu)
  • For the laboratory synthesis of NBS, succinimide is dissolved in a solution of sodium hydroxide, ice, and water, then bromine is added, and the N-bromosuccinimide is filtered out as a precipitate. (fsu.edu)
  • Yu,W.N Bromosuccinimide Mediated Radical Cyclization of 3 Arylallyl Azides: Synthesis of. (ourneighborhoodschool.com)
Tryptophan3
  • Spande TF, Witkop B (1967) Determination of the tryptophan content of proteins with N -bromosuccinimide. (springer.com)
  • Publications] 大西 正健: 'Effect of modification of tryptophan residues of cyclo=dextrin glucanotransferate with N-bromosuccinimide on the enzyme-catalyzed byelvolysis of Soluble Starch and cyclo wexcole. (nii.ac.jp)
  • Publications] 大西 正健: 'Modification of tryptophan residues of cyclodextrin glucanotransfevase with N-bromosuccinimide on the formation of cycloamyloses from maltose as a sabstrate. (nii.ac.jp)
Reagent1
  • N-Bromosuccinimide or NBS is a chemical reagent used in radical substitution, electrophilic addition, and electrophilic substitution reactions in organic chemistry. (wikipedia.org)
Reaction2
  • Complete the mechanism and the products for the reaction of 2-pentene with N-bromosuccinimide (NBS). (transtutors.com)
  • Reaction of alkenes with N-bromosuccinimide and Et3N.3HF produces vic-bromofluoroalkanes in high yields. (epfl.ch)
Zhang1
  • JINGPING ZHANG: "N-Bromosuccinimide/l,8-Diazabicyclo[5.4.1] undec-7-ene Combination: P-Amination of Chalcones via a Tandem Bromoamination/Debromination Sequence", ORG. (sumobrain.com)
Tyrosine1
  • The essential role of tyrosine residue(s) of cardiotoxin II in the biological activity of the toxin was evaluated using N-bromosuccinimide. (ias.ac.in)
Bromine3
  • N -Bromosuccinimide (NBS) is a brominating and oxidizing agent that is used as source for bromine in radical reactions (for example: allylic brominations) and various electrophilic additions. (organic-chemistry.org)
  • N-bromosuccinimide ( NBS ) is characterized by a molecular weight of 177.99, a chemical composition of 4 carbon, 4 hydrogen, 1 bromine, 1 nitrogen, and two oxygen atoms per molecule, and a faint bromine odor. (fsu.edu)
  • The catalytic asymmetric bromoamination of chalcones with N -bromosuccinimide as both bromine and amide source was realized by using a chiral N , N ′-dioxide-Sc(NTf 2 ) 3 complex as an efficient catalyst. (rsc.org)
Brominations1
  • Brominations with N-Bromosuccinimide and Related Compounds. (wikipedia.org)
Sodium dodecyl1
  • The lethal activity was inactivated by N-bromosuccinimide, N-chlorosuccinimide, chloramine-T, and sodium dodecyl sulfate. (asm.org)
Dyes2
  • Two sensitive spectrophotometric methods are presented for the assay of pantoprazole sodium sesqui hydrate (PNT) in bulk drug and in formulations using N-bromosuccinimide (NBS) and two dyes, methyl orange and indigo carmine, as reagents. (uni-mysore.ac.in)
  • The methods use N-bromosuccinimide [NBS] and two- dyes , namely quinoline yellow and metanil yellow, as reagents . (bvsalud.org)
Compounds3
  • An efficient one-pot transformation of β-hydroxycarbonyl compounds to α-brominated 1,3-dicarbonyl compounds is achieved with MoO 2 Cl 2 in the presence of N -bromosuccinimide. (organic-chemistry.org)
  • N-haloamides, well known as N-bromosuccinimide, is a very important member of this class of compounds and has received a considerable attention as an oxidizing agent for a wide range of functional groups in both acidic and alkaline media [ 2 - 4 ]. (hindawi.com)
  • with N-bromosuccinimide in an aprotic polar solvent, in the presence of a base to obtain the corresponding desired carbonyl compounds and/or their derivative. (sumobrain.com)
Reactions2
  • Because many reactions involving N-bromosuccinimide are extremely exothermic, including violent or explosive reactions with aniline, diallylsulfide, hydrazine, and propiononitrile, special care is necessary for storage and handling. (fsu.edu)
  • Reactions of (E)-cyclooctene with N-bromosuccinimide in the presence of water, and methanol, resp. (springer.com)
Determination1
  • A. Ibrahim, A. Darwish Samiha, M. Hussein Ashraf, and I. Mahmoud Ahmed Hassan, "Sensitive spectrophotometric method for the determination of H2-receptor antagonists by means of N-bromosuccinimide and p-aminophenol," International Journal of Biomedical Science , vol. 3, no. 2, pp. 123-130, 2007. (hindawi.com)
Ratio1
  • The determined stoichiometric ratio was 1 : 1 (dextrose : N-bromosuccinimide). (hindawi.com)
Modification1
  • Modification of the Streptomyces R61 DD-peptidase by N-bromosuccinimide resulted in a rapid loss of enzyme activity. (portlandpress.com)
Chemical1
  • As a hazardous chemical, N-bromosuccinimide is harmful if swallowed, inhaled, or absorbed through the skin, and can cause severe irritation to skin, eyes, and the respiratory tract. (fsu.edu)
Water4
  • An efficient and user-friendly procedure has been developed for the oxidative deprotection of tetrahydropyranyl (THP) ethers with N -bromosuccinimide (NBS) using β-cyclodextrin (β-CD) in water. (organic-chemistry.org)
  • N-bromosuccinimide (0.0067 mol/l) and methylene blue (0.031 mol/l) were prepared by dissolving 120 mg of N-bromosuccinimide and 1000 mg of methylene blue, respectively in distilled water and diluted to 100 ml. (ijpsonline.com)
  • Aripiprazole (5-20 μg/ml)+1.0 ml of N-bromosuccinimide (0.0067 mol/l)+0.5 ml of methylene blue (0.01%)+diluted to 10 ml with distilled water. (ijpsonline.com)
  • Appearing as an off-white powder, N-bromosuccinimide melts between 173 and 176 degrees Celsius, and is soluble in acetone and slightly soluble in water. (fsu.edu)
Market1
  • In this report, the global N-Bromosuccinimide market is valued at USD XX million in 2016 and is expected to reach USD XX million by the end of 2022, growing at a CAGR of XX% between 2016 and 2022. (rnrmarketresearch.com)
Treatment2
  • In this study, we first examined the immunogenicity of brominated protein prepared by treatment of N-bromosuccinimide (NBS). (nih.gov)
  • However, the electron-deficient TIPs were easily oxidized to the corresponding DIPs by treatment with N-bromosuccinimide. (uio.no)
Title1
  • 2002) with N -bromosuccinimide (NBS) and obtained the title compound in poor yield. (iucr.org)
Activities1
  • Additives of Hg2+ and N- Bromosuccinimide strongly inhibited three xylanases activities. (ncl.edu.tw)
N-Bromosuccinimide (NBS)
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