One of the BENZODIAZEPINES that is used in the treatment of ANXIETY DISORDERS.
Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.
An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam.
An immunoenzyme test for the presence of drugs and other substances in urine and blood. The test uses enzyme linked antibodies that react only with the particular drug for which the sample is being tested.
A late-appearing component of the event-related potential. P300 stands for a positive deflection in the event-related voltage potential at 300 millisecond poststimulus. Its amplitude increases with unpredictable, unlikely, or highly significant stimuli and thereby constitutes an index of mental activity. (From Campbell, Psychiatric Dictionary, 6th ed)
A genus of basidiomyceteous fungi in the family POLYPORACEAE found mostly on living trees or dead wood.
An estrogenic steroid produced by HORSES. It has a total of four double bonds in the A- and B-ring. High concentration of euilin is found in the URINE of pregnant mares.
A group of two-ring heterocyclic compounds consisting of a benzene ring fused to a diazepine ring.
Feeling or emotion of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.
Persistent and disabling ANXIETY.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Chemical substances excreted by humans that elicit behavior or physiological responses from other humans. Perception of these chemical signals may be olfactory or by contact.
Elements of limited time intervals, contributing to particular results or situations.
Stress wherein emotional factors predominate.
It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)
The interchange of goods or commodities, especially on a large scale, between different countries or between populations within the same country. It includes trade (the buying, selling, or exchanging of commodities, whether wholesale or retail) and business (the purchase and sale of goods to make a profit). (From Random House Unabridged Dictionary, 2d ed, p411, p2005 & p283)
An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.
Individuals responsible for various duties pertaining to the medical office routine.
Methods used to induce premature oocytes, that are maintained in tissue culture, to progress through developmental stages including to a stage that is competent to undergo FERTILIZATION.
A bacteria isolated from normal skin, intestinal contents, wounds, blood, pus, and soft tissue abscesses. It is a common contaminant of clinical specimens, presumably from the skin of patients or attendants.
The study of the structure, preparation, properties, and reactions of carbon compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Process that is gone through in order for a drug to receive approval by a government regulatory agency. This includes any required pre-clinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance of the drug.
Pollution prevention through the design of effective chemical products that have low or no toxicity and use of chemical processes that reduce or eliminate the use and generation of hazardous substances.
The conformation, properties, reaction processes, and the properties of the reactions of carbon compounds.
Removal of a drug from the market due to the identification of an intrinsic property of the drug that results in a serious risk to public health.
A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
A plant species of the family VACCINIUM known for the sour fruit which is sometimes used for urinary tract infections.
Liquids that are suitable for drinking. (From Merriam Webster Collegiate Dictionary, 10th ed)
A plant family of the order Caryophyllales, subclass Caryophyllidae, class Magnoliopsida. Some members contain triterpenoid saponins.
That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.

Investigation into some aspects of EMIT d.a.u., TLC, and GC-MS urinalysis of bromazepam. (1/15)

Among the different 1,4-benzodiazepine urinary metabolites, those of bromazepam possess distinctive chemical features that may be used in their selective isolation and detection. The detection of bromazepam metabolites in urine was carried out using EMIT d.a.u., thin-layer chromatography (TLC), and gas chromatography-mass spectrometry (GC-MS). The positive EMIT d.a.u. benzodiazepine assay for bromazepam was found to be due to the 3-hydroxybromazepam (3HOB) metabolite. The detection by TLC and GC-MS was carried out after enzyme or acid hydrolysis of the glucuronide conjugates. Both the 2-amino-3-hydroxy5-bromobenzoylpyridine (AHBBP) metabolite and the acid hydrolysis product of 3-HOB, 2-amino-5-bromobenzoylpyridine (ABBP), were selectively detected by TLC. The bromazepam metabolites in urine could be both isolated and detected selectively by GC-MS in the presence of the metabolites of other 1,4-benzodiazepines that were sometimes used in combination with bromazepam. Both 3-HOB and AHBBP were detected by GC-MS only after trimethylsilyl (TMS) derivatization and not as the free compounds or the acetyl derivatives. Only ABBP was detected in three forms: ABBP, the TMS derivative, and the acetyl derivative. Evidence has been obtained from the enzyme hydrolysis and the TLC studies for the formation of the glucuronide conjugate of AHBBP at the 3-OH group rather than at the 2-NH2 group. All the results have been validated using reference 3-HOB and AHBBP.  (+info)

Hair to document drug-facilitated crimes: four cases involving bromazepam. (2/15)

The use of a drug to modify a person's behavior for criminal gain is not a recent phenomenon. However, the recent increase in reports of drug-facilitated crimes (sexual assault, so-called DFSA, robbery) has caused alarm in the general public. Drugs used can be difficult to detect (active products at low dosages, chemical instability), possess amnesic properties, and can be quickly cleared from body fluids. In case of long delay between the alleged crime and clinical examination, collection of blood or even urine can be of little value. This is the reason why this laboratory developed an original approach based on hair testing by liquid chromatography-tandem mass spectrometry. To explore the detectability of a single absorption of bromazepam in hair, two volunteers (male and female) received a 6-mg dose. A strand of hair was sampled about one month after exposure and was cut into three segments of 2-cm long. After pulverization, 20 mg of hair was incubated overnight in a phosphate buffer (pH 8.4). The aqueous phase was extracted with 5 mL of a mixture of diethyl ether/methylene chloride (80:20) in the presence of diazepam-d5, which was used as internal standard (IS). Hair extract was separated on a XTerra MS C18 column using a gradient of acetonitrile and formate buffer. Detection was based on two daughter ions: transitions m/z 316.0 to 182.2 and 209.3 and m/z 290.1 to 154.1 and 198.2 for bromazepam and the IS, respectively. In the hair of the two subjects, bromazepam was detected in the proximal segment at 0.8 and 4.7 pg/mg, respectively. Hair analysis was applied to four authentic criminal cases. In the two first cases, bromazepam tested positive in the corresponding hair segment at 5.7, and 10.3 pg/mg. In another case, head hair was sampled 19 weeks after the alleged offense, and its length (< 4 cm) did not allow analysis of the corresponding period. However, 4.1 pg/mg of bromazepam was quantified in the victim's pubic hair. In these three cases, concentrations were consistent with a single exposure to bromazepam. In the last case, bromazepam was detected at 15 pg/mg in the segment corresponding to the period of the alleged offence but also in the range 2 to 7 pg/mg in the four other consecutive segments, making a single exposure statement difficult.  (+info)

[Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study]. (3/15)

The P300 component of the event-related potential (ERP) is a general measurement of "cognitive efficiency". It is an index of the ability of an individual's central nervous system (CNS) to process incoming information. OBJECTIVE: To compare the neuromodulatory effects of caffeine and bromazepam on the visual ERP (P300), in relation to a P300 normative database. METHOD: 15 right-handed individuals (7 male and 8 female), between 20 and 30 years of age, healthy, free of any cognitive impairment and not making use of psychoactive substances were studied. Participants were submitted to a visual discrimination task, which employed the "oddball" paradigm, after the administration of caffeine and bromazepam, in a randomized, double-blind design. RESULTS: Statistically significant differences were observed when the caffeine and bromazepam conditions were compared to the normative database. CONCLUSION: The present results suggest that caffeine and bromazepam have distinct modulatory effects on CNS functioning.  (+info)

Analysis of the influence of bromazepam on cognitive performance through the visual evoked potential (P300). (4/15)

Benzodiazepines have been used in the pharmacological treatment of anxiety for over four decades. However, very few studies have combined bromazepam and event-related potentials (ERP). The present study aimed at investigating the modulatory effects of this drug on brain dynamics. Specifically, the effects of bromazepam (3 mg) on the P300 component of the ERP were tested in a double-blind experiment. The sample, consisting of 15 healthy subjects (7 male and 8 female), was submitted to a visual discrimination task, which employed the "oddball" paradigm. Electrophysiological (P300) and behavioral measures (stroop, digit span, and reaction time) were analyzed across three experimental conditions: placebo 1, placebo 2, and bromazepam. Results suggest that the effects of bromazepam (3 mg) on cognitive processes are not apparent. In spite of what seems irrefutable in current literature, bromazepam did not produce evident effects on the behavioral and electrophysiological variables analyzed.  (+info)

Comparison of behavioral effects after single and repeated administrations of four benzodiazepines in three mice behavioral models. (5/15)

The behavioral and clinical profiles of various benzodiazepines after acute and chronic treatment are not well defined and may differ. The aim of this study was to evaluate the behavioral profiles of alprazolam, bromazepam, diazepam and lorazepam in mice after single and repeated (every half-life for seven half-lives) administrations using a stimulation-sedation test (actimeter), a myorelaxation test (rotarod), and an anxiolysis test ("four plates"). A dose range from 0.03 to 4 mg/kg was used. A single administration of alprazolam showed stimulating and anxiolytic effects which diminished after repeated administration. Lorezapam's sedative effect diminished but its anxiolytic effect increased upon repeated administration. Except for lorazepam, the myorelaxing effect of all four drugs increased after repeated treatment. These results suggest that the behavioral profile of benzodiazepines may not be identical during acute and chronic treatment. These differences may be present in clinical treatment and warrant investigation in humans.  (+info)

Influence of bromazepam on cortical interhemispheric coherence. (6/15)

Benzodiazepines are among the most commonly prescribed medications due to their therapeutic efficacy in reducing anxiety and inducing sleep. Consequently, they have been widely employed in the pharmacological treatment of several disorders. Nevertheless, few studies have analyzed the effects of bromazepam in electroencephalographic activity (EEG). The present study aimed at investigating the modulatory effects of this drug on brain dynamics. Specifically, the effects of bromazepam (3mg) on EEG coherence were tested in a double-blind experiment. The sample, consisting of 10 healthy subjects (5 male and 5 female), was submitted to ten minutes of EEG recording. The electrophysiological measure (coherence) was analyzed across three experimental conditions: bromazepam, placebo 1, and placebo 2. Results indicate that bromazepam significantly increases cortical interhemispheric coherence.  (+info)

The effects of bromazepam on the early stage of visual information processing (P100). (7/15)

The early stages of visual information processing, involving the detection and perception of simple visual stimuli, have been demonstrated to be sensitive to psychotropic agents. The present study investigated the effects of an acute dose of bromazepam (3 mg), compared with placebo, on the P100 component of the visual evoked potential and reaction time. The sample, consisting of 14 healthy subjects (6 male and 8 female), was submitted to a visual discrimination task, which employed the "oddball" paradigm. Results suggest that bromazepam (3 mg) impairs the initial stage of visual information processing, as observed by an increase in P100 latency.  (+info)

Alterations in brain 5-hydroxytryptamine metabolism during the 'withdrawal' phase after chronic treatment with diazepam and bromazepam. (8/15)

1 Daily administration of diazepam or bromazepam (10 mg/kg) for 22 days significantly increased the activity of mid-brain tryptophan hydroxylase by 36% and 39%, respectively. The concentration of tryptophan was also enhanced in the mid-brain region of rats subjected to benzodiazepine treatment.2 Chronic therapy with either of the two anti-anxiety agents enhanced the endogenous levels of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in cerebral cortex, hypothalamus, pons-medulla, mid-brain and striatum.3 Whereas diazepam treatment decreased (13%) the activity of monoamine oxidase in mid-brain, bromazepam failed to exert any effect, suggesting that the observed elevation in 5-hydroxy-indoleacetic acid levels is not associated with enhanced deamination of 5-hydroxytryptamine.4 Discontinuation of treatment for 48 h significantly decreased the activity of mid-brain tryptophan hydroxylase to levels that were significantly lower than those seen for benzodiazepine-treated and normal rats. The concentrations of mid-brain tryptophan and 5-hydroxytryptamine were also reduced in various brain regions examined.5 Withdrawal from diazepam or bromazepam therapy further augmented the levels of brain 5-hydroxyindoleacetic acid.6 The results demonstrate that the depressant effects on behaviour of these agents are accompanied by increased metabolism of 5-hydroxytryptamine in the brain. Withdrawal from these minor tranquillizers, on the other hand, reduces the synthesis of this indoleamine.  (+info)

We describe a rare case of diffuse macroscopic discoloration and chemical gastritis due to chronic bromazepam intake. The chemical composition of pharmaceuticals has to be considered at endoscopy and it is evident that some chemical substances damage the epithelial tissue and lead to clinical symptoms. Endoscopy was performed in an 82-year-old patient due to gastroesophageal reflux symptoms and epigastric pain. Gastroscopy showed a hiatal hernia and a scarred duodenal bulb. More striking was the yellow-brownish discoloration of the gastric and the duodenal mucosa. The gastric antrum and the duodenal bulb showed local discoloration that could not be rinsed off. The medical history indicated that bromazepam (6 mg) had been used daily as a sleeping aid in the previous two years. The histopathological findings showed appearances of chemical gastritis. Within the lamina propria and on the epithelial surface there were granules. There was no foreign body reaction to these granules. Corpus mucosa showed a mild
Buy Lexotanil 3mg (bromazepam). Bromazepam, sold under many brand names, is a benzodiazepine. It is mainly an anti-anxiety agent with similar side effects to diazepam (Valium). In addition to being used to treat anxiety or panic states, bromazepam may be used as a premedicant prior to minor surgery. Bromazepam typically comes in doses of 3 mg and 6 mg tablets.. Bromazepam is contraindicated and should be used with caution in women who are pregnant, the elderly, patients with a history of alcohol or other substance abuse disorders and children. Prolonged use of bromazepam causes tolerance and may lead to both physical and psychological dependence on the drug, and as a result, it is a medication which is controlled by international law.. ...
Bromazepam Bromazepam Systematic (IUPAC) name 9-bromo-6-pyridin-2-yl-2,5-diazabicyclo[5.4.0]undeca-5,8,10,12-tetraen-3-one Identifiers CAS number 1812-30-2 ATC
Bromazepam Bromazepam Systematic (IUPAC) name 9-bromo-6-pyridin-2-yl-2,5-diazabicyclo[5.4.0]undeca-5,8,10,12-tetraen-3-one Identifiers CAS number 1812-30-2 ATC
Bromazepam lorazepam has been prescribed cranberry juice xanax, 2015 this class. 2017 table 1 min - but is the only difference between lorazepam versus
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|b|Uses|/b||br| This medication is used to relieve anxiety, nervousness and tension.|br||br| |b|Notes|/b||br| Do not share this medication with others.|br||br| |b|Storage|/b||br| Store this medication at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from heat and light. Do not store in the bathroom. Keep this and all medications out of the reach of children.|br||br| |b|How To Use|/b||br| Take this medication by mouth exactly as directed by your doctor. Do not increase your dose, use it more frequently or use it for a longer period of time than prescribed because this drug can be habit-forming. If used for an extended period, do not suddenly stop using this drug without your doctors approval. Over time, this drug may not work as well. Consult your doctor if this medication stops working well.|br||br| |b|Side Effects|/b||br| Drowsiness, dizziness, or loss of coordination may occur. Dry mouth, headache or stomach upset rarely occurs. If any of these effects
|b|Uses|/b||br| This medication is used to relieve anxiety, nervousness and tension.|br||br| |b|Notes|/b||br| Do not share this medication with others.|br||br| |b|Storage|/b||br| Store this medication at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from heat and light. Do not store in the bathroom. Keep this and all medications out of the reach of children.|br||br| |b|How To Use|/b||br| Take this medication by mouth exactly as directed by your doctor. Do not increase your dose, use it more frequently or use it for a longer period of time than prescribed because this drug can be habit-forming. If used for an extended period, do not suddenly stop using this drug without your doctors approval. Over time, this drug may not work as well. Consult your doctor if this medication stops working well.|br||br| |b|Side Effects|/b||br| Drowsiness, dizziness, or loss of coordination may occur. Dry mouth, headache or stomach upset rarely occurs. If any of these effects
Used with the permissions of NIST Mass Spectrometry Data Center Collection (C) 2008 copyright by the U.S. Secretary of Commerce on behalf of the United States of America. All rights reserved ...
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DR ANTHONY MELVIN CRASTO, Worlddrugtracker, Born in Mumbai in 1964 and graduated from Mumbai University, Completed his PhD from ICT ,1991, Mumbai, India, in Organic chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues, Currently he is working with GLENMARK- GENERICS LTD, Research centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India. Prior to joining Glenmark, he worked with major multinationals like Hoechst Marion Roussel, now sSanofi, Searle India ltd, now Rpg lifesciences, etc. he is now helping millions, has million hits on google on all organic chemistry websites. His New Drug Approvals, Green Chemistry International, Eurekamoments in organic chemistry are some most read blogs He has hands on experience in initiation and developing novel routes for drug molecules and implementation them on commercial scale over a 25 year tenure, good knowledge of IPM, GMP, Regulatory aspects, he has several international drug patents published ...
DR ANTHONY MELVIN CRASTO, Worlddrugtracker, Born in Mumbai in 1964 and graduated from Mumbai University, Completed his PhD from ICT ,1991, Mumbai, India, in Organic chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues, Currently he is working with GLENMARK- GENERICS LTD, Research centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India. Prior to joining Glenmark, he worked with major multinationals like Hoechst Marion Roussel, now sSanofi, Searle India ltd, now Rpg lifesciences, etc. he is now helping millions, has million hits on google on all organic chemistry websites. His New Drug Approvals, Green Chemistry International, Eurekamoments in organic chemistry are some most read blogs He has hands on experience in initiation and developing novel routes for drug molecules and implementation them on commercial scale over a 25 year tenure, good knowledge of IPM, GMP, Regulatory aspects, he has several international drug patents published ...
An aircraft power distribution system is disclosed that includes a power distribution box. A generator supplies power to the power distribution box, and a load receives power from the power distribution box. The power distribution box includes a board supporting plug-in pins receiving the power. A contactor is supported by the board to selectively providing power to a secondary power distribution connector supported on the board. The board includes power traces that are run within the board to connect the plug-in pins to the secondary power distribution connector. Protection and secondary power distribution circuitry is also supported by the board and connected to the contactors and/or power traces by control traces. The power and control traces eliminate loose wiring and harnesses.
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Benzodiazepines are drugs which act upon the GABA(A) receptor, and produce a general set of effects which vary by compound, mostly being sedative, hypnotic, anxiolytic, anticonvulsant and muscle relaxant. The first benzodiazepine, Chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955, and made available in 1960 by Hoffmann-La Roche, which has also marketed diazepam (Valium) since 1963. = Dosage = {, class=wikitable sortable ,+Comparison of benzodiazepines ! Chemical name (brand name) ! Half-Life [Active Metabolites] ! Dose Equiv. of 10mg Diazepam (Oral) ! Class ,- , Alprazolam (Xanax) , 6 - 12 hours , 0.5 mg , Anxiolytic ,- , Bromazepam (Lexotan, Lexomil) , 10 - 20 hours , 5 - 6 mg , Anxiolytic ,- , Brotizolam , 2 - 6 hours , .25mg , Hypnotic ,- , Chlordazepoxide (Librium) , 5 - 30 hours [36 - 200 hours] , 25 mg , Anxiolytic ,- , Clobazam (Frisium) , 12 - 60 hours , 20 mg , Anxiolytic ,- , Clonazepam (Klonopin) , 18 - 50 hours , 0.5 mg , Anxiolytic ,- , Clorazepate ...
Perkiraan Dosis Ekuivalen Benzodiazepin Perkiraan Dosis Oral Ekuivalen, mg dosis kadar tertinggi, jam qaktu paruh, jam Alprazolam (Xanax) 0.5 1-2 12 Bromazepam (Lexotan) 3 1-4 20 Chlordiazepoxide (Librium) 25 1-4 100 Clonazepam (Klonopin) 0.25 1-4 34 Clorazepate (Tranxene) 10 0.5-2 100 Diazepam (Valium) 5 1-2 100 Flurazepam (Dalmane) 15 0.5-1 100 Lorazepam (Ativan) 1 1-4…
Mylan-Bromazepam: Bromazepam belongs to the class of mediations known as benzodiazepines. It is used for the short-term relief of symptoms of excessive anxiety. It works to reduce anxiety by affecting certain substances in the brain called neurotransmitters.
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Pharmaceuticals are considered to be important environmental contaminants. The aim of this study was to evaluate their presence in water intended for public supply to Municipally of Rio de Janeiro, Brazil. The regional environmental assessment was done from the analysis of surface water and distribution for the presence of psychiatric drugs. The study reveals the presence of benzodiazepine derivatives in all samples of surface water samples of the Guandu River, with the amounts of 42 ng L-1, 198 ng L-1 and 335 ng L-1 for bromazepam, clonazepam, and diazepam, respectively. The population served by Companhia Estadual de à guas e Esgotos (CEDAE) is the order of ten million. Psychiatric pharmaceuticals, in particular, are thought to impose significant ecological risks. A better understanding of the real impact of these pollutants implies a comprehensive evaluation of their persistence and fate in environmental matrices. The studies presented in this article are intended to contribute to improve the
Acute myocardial infarction (AMI): state anxiety, stress hormone response and clinical course in patients treated and not treated with bromazepam. [Italian ...
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Radiation exposure: Find the most comprehensive real-world symptom and treatment data on radiation exposure at PatientsLikeMe. 16 patients with radiation exposure experience fatigue, depressed mood, anxious mood, Pain, and insomnia and use Bromazepam and Chymotrypsin-trypsin to treat their radiation exposure and its symptoms.
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The key goal of electric power distribution companies is to provide a high quality of service with a low cost of operation. The growing customer needs requires a re-distribution of the Power over various nodes of the Distributed Generation (DG) facilitates. The re-distribution might cause over load on various parts of the networks which if not correctly optimized might increase the cost of maintenance and affect the overall network reliability. This is why it is urgently requited to find a methodology that can effectively provide a schema for re-distribution of the power and achieve both customers and power companies contracting objectives. In this paper, we explore our new proposed idea of using a simulated annealing based local search technique to provide an efficient power load distribution for distributed generation network. On doing this, we will apply our approach on the famous IEEE14 and IEEE30 power systems as two test cases. The developed results show the significant of the proposed approach.
Light rail systems interact with utility AC power distribution systems in many areas where running rails run parallel to the utility AC power transmission and distribution lines. This interaction may produce a 60Hz voltage on the running rail relative to the earth, adjacent to that the running rail. Since the running rails on modern systems are reasonably well isolated, this can result in potentials that can cause significant AC voltage on the rail that can cause instrumentation problems and personnel safety issues working on right-of-way (ROW). This effect is generally seen in areas where electrical distribution lines (power lines) run parallel to the running rail.. This paper will describe methodology used to mitigate the problems by selecting a suitable capacitor filter bank network that provides a highly conductive path for the induced AC voltages between the substation grounding grid and the running rail at the traction power substation location. The filter actually provides lower ...
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A telephone and auxiliary power distribution system in a building has a flexible multi-conductor signal and power distribution cable; which cable originates from a central signal & power management facility located near the point where the telephone utility line enters the building and extends from there to each of numerous locations within the building at which a fire-hazard-proof signal & power outlet is wanted; each of which outlets is adapted to service one of plural different loads, such as a wide variety of telephone and telephone-related instruments, smoke detectors, PCs, TVs & VCRs, clocks and timers, thermostats, door chimes and buttons, modems, fax machines, lamps & lights, Class-2 & Class-3 sub-circuits, etc. The central signal and power management facitility, which is connected with the telephone utility line, the electric utility power line, the gas utility gas supply line and a water supply line, serves: (i) to connect the telephone utility line with the signal and power distribution
A method and system are given for a coupling a data signal over a power distribution system. An inductive signal coupler has two windings. The first winding is in series with a line conductor of the power distribution system. A capacitor is connected between the first line conductor and a second line conductor of the distribution system such that the capacitor presents a high impedance to a power signal and a low impedance to a data signal. A communication device is connected to the second winding so that a data signal can be coupled between the communication device and the distribution system.
This project will trial a new type of fault indicator (Metrysense 5000) which will help locate faults in a shorter time compared to a full line patrol, therefore reducing operational costs, the number of customers off supply and Customer Minutes Lost (CMLs). This will also decrease the time a live conductor could potentially be on the ground, and therefore will reduce the risk to members of the public.. Metrysense 5000 is a fault indicator suitable for the arc suppression coil network arrangement, which can offer detailed information to a DNOs control centre on the fault location. This has been used successfully in other countries for similar network configurations but at higher voltage levels. This technology has never been tested in the United Kingdom.. Metrysense 5000 will send real time data once integrated into UK Power Networks and WPDs SCADA system. As part of the project, the fault indicator will be tested first at the Power Networks Demonstration Centre (PNDC) in a simulated network ...
Loss of Mission. SUMMARY:. Explosion due to electrical short. Loss of O2 and EPS.. EVENT DESCRIPTION:. Apollo 13 launched on April 11, 1970. On April 13, 1970 during trans-lunar flight at approximately 56 hours, one of the two Service Module oxygen tanks over-pressurized and exploded. This caused the loss of oxygen in that tank and a leak of oxygen out of the remaining tank. This resulted in the loss of all three fuel cells, loss of the primary oxygen source, and the loss of electrical power to the Command Module (except for the entry batteries). The mission was able to continue with the use of the Lunar Module, and the crew safely returned.. Prior to launch, the following conditions resulted in the oxygen tank failing during the mission: By design the cryogenic oxygen tank required both electrical heaters to maintain pressure, and fans to prevent stratification. The tank was a complex assembly with blind installation of the quantity probe, heater/fan assembly, and fill tube. This design leaves ...
Society relies more and more on a continuous supply of electricity. However, while underinvestments in reliability lead to an unacceptable number of power interruptions, overinvestments result in too high costs for society. To give incentives for a socioeconomically optimal level of reliability, quality regulations have been adopted in many European countries. These quality regulations imply new financial risks for the distribution system operator (DSO) since poor reliability can reduce the allowed revenue for the DSO and compensation may have to be paid to affected customers.This thesis develops a method for evaluating the incentives for reliability investments implied by different quality regulation designs. The method can be used to investigate whether socioeconomically beneficial projects are also beneficial for a profit-maximizing DSO subject to a particular quality regulation design. To investigate which reinvestment projects are preferable for society and a DSO, risk-based methods are ...
Kinetics eddy current clutch field exciter is a SCR regulated rectifier system designed for the application of supplying regulated variable DC power.
Implementing the automation of electric distribution networks, from simple remote control to the application of software-based decision tools, requires many con
Reducing the interconnect size with each technology node and increasing speed with each generation increases IR-drop and Ldi/dt noise. In addition to this, the drive for more integration increases the average current requirement for modern ULSI design. Simultaneous switching of core logic blocks and I/O drivers produces large current transients due to power distribution network parasitics at high clock frequency. The current transients are injected into the power distribution planes thereby inducing noise in the supply voltage. The part of the noise that is caused by switching of the internal logic load is core switching noise. The core logic switches at much higher speed than driver speed whereas the package inductance is less than the on-chip inductance in modern BGA packages. The core switching noise is currently gaining more attention for three-dimensional integrated circuits where on-chip inductance is much higher than the board and package inductance due to smaller board, and package. The ...
European networks will require €600 billion of investment by 2020. Two thirds of this investment will take place in distribution grids. The DSO share of overall network investments is estimated to grow to almost 75% by 2035, and to 80% by 2050.. DSO investments include building new capacity and refurbishing and replacing existing assets as they reach the end of their technical lifetime. Investments are also driven by a changing distribution system, with a greater role for new loads like electric vehicles, for distributed generation like rooftop solar panels, and for smart meters.. As regulated companies, the DSO investment framework is determined by regulation at the national level.. Electricity use in transport may only make up a small part of total electricity demand for many years to come, but e-mobility could nevertheless have a big impact on load, in particular if motorists all plug in their vehicles during the peak load time.. Active load management will be needed to avoid network ...
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Individuals that inherit genomic mutation from their parents are at a bigger risk of certain varieties of cancers. Familial cancer syndromes are the group of cancers wherever patients inherit genomes that dont perform properly, increasing the chance of developing cancer.. Approximately 100 familial cancer syndromes are known and this vary is growing. The genes identified as increasing the chance of cancer are usually chromosome dominant (only one amongst the try of bodys must have the mutation so as for it to be expressed) though theyll even be chromosome recessive (both chromosomes ought to have the mutation for it to be expressed). The identification of these genes has improved designation and helped verify new cancer treatments.. The growing use of biological therapies that have an effect on cellular signal pathways has revolutionized the treatment of cancer, a trend which will continue as treatment ways in which could also be personalized to people once genomic typing of their cancer is ...
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Power distribution monitoring systems are enhanced and now include power quality analysis capabilities and unlimited trip curve shaping.Whats new in electrical products and technologies? Well, the Electric West 95 Show held in Anaheim, Calif. last month highlighted many new products. From a performance viewpoint, however, there are some surprises. One such surprise is the enhanced performance of
Specificaties:. Input Voltage: AC 100-240V / DC 11-18V. Charge Circuit Power: 250W Power Distribution. Discharge Circuit Power: 2x 10W. Charge Current: 2x 0,1 - 10A (Max. 120W). Discharge Current: 2x 0,1 - 2A (Max. 10W). Current Drain Balancing Port: Max 300mA/cell. Trickle Charging Current: 50mA-300mA & Off. LiPo / LiFe / LiIon / LiHV Cell Count: 2x 1-6 S. Cell Terminate Voltage:. LiPo: 4.20V ± 0.02V. LiFe: 3.60V ± 0.02V. LiIon: 4.10V ± 0.02V. LiHV: 4.35V ± 0.02V. NiMH / NiCd Cell Count: 1-15 Cells. PB Battery Voltage: 2x 2-20V. DC Power Supply Output: 13.8V - Max. 150W. USB Output: 5V - 2.1A. Dimensions: 184x146x70mm. Net Weight: 1.293g. ...
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  • Prolonged use of bromazepam causes tolerance and may lead to both physical and psychological dependence on the drug, and as a result, it is a medication which is controlled by international law. (pharmacyinn.com)
  • Bromazepam , sold under many brand names, is a benzodiazepine. (pharmacyinn.com)
  • Bromazepam is contraindicated and should be used with caution in women who are pregnant, the elderly, patients with a history of alcohol or other substance abuse disorders and children. (pharmacyinn.com)
  • Bromazepam typically comes in doses of 3 mg and 6 mg tablets. (pharmacyinn.com)
  • We describe a rare case of diffuse macroscopic discoloration and chemical gastritis due to chronic bromazepam intake. (beds.ac.uk)
  • This is the first case in literature that shows a chemical gastritis after bromazepam intake. (beds.ac.uk)
  • The active pharmaceutical ingredient is bromazepam [(C 14 H 10 BrN 3 O), (Figure 4 )] containing a bromo substituent. (beds.ac.uk)
  • The medical history indicated that bromazepam (6 mg) had been used daily as a sleeping aid in the previous two years. (beds.ac.uk)
  • In addition to being used to treat anxiety or panic states, bromazepam may be used as a premedicant prior to minor surgery. (pharmacyinn.com)
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  • Lexotanil (Bromazepam) Bromazepam is a benzodiazepine derivative drug, patented by Roche in 1963 and developed clinically in the 1970s. (blessedpharmacy.com)
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  • Lexotanil contains the active ingredient bromazepam. (drugs-track.online)
  • Bromazepam (Lexotanil) 3mg bitartrate and acetaminophen are supplied in tablet form for oral administration. (jasonscottmedical.com)
  • BROMAZEPAM lexotanil 3 mg (marketed under several brand names, including Lectopam, Lexotan, Lexilium, Lexaurin, Brazepam, Rekotnil, Bromaze, Somalium and Lexotanil) is a benzodiazepine derivative drug, patented by Roche in 1963 and developed clinically in the 1970s.It has mainly an anti-anxiety agent with similar side effects to diazepam (Valium). (mypharmworld.com)
  • What is Bromazepam lexotanil 3 mg used for? (mypharmworld.com)
  • Lexotanil (Bromazepam) is useful for the short-term, symptomatic relief of manifestations of excessive anxiety in patients with anxiety neurosis. (eurdoc.com)
  • Lexotanil (Bromazepam) is contra-indicated in-patients with known hypersensitivity to benzodiazepines, myasthenia gravis, severe hepatic insufficiency, severe respiratory insufficiency or sleep apnea syndrome. (eurdoc.com)
  • Lexotanil (Bromazepam) is not recommended for use in patients with depressive disorders or psychosis. (eurdoc.com)
  • Lexotanil (also known as Bromazepam) side effects are usually temporary, and fade with continued treatment. (macromass.cn)
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  • If you have been taking this medication regularly for a long time (i.e., longer than a month), do not stop taking bromazepam without first speaking to your doctor. (canada.com)
  • Can I stop taking bromazepam suddenly? (mypharmworld.com)
  • Drug withdrawal catatonia has been described as an effect of bromazepam withdrawal (5a). (hajixuk.ru)
  • Electrophysiological (P300) and behavioral measures (stroop, digit span, and reaction time) were analyzed across three experimental conditions: placebo 1, placebo 2, and bromazepam. (scielo.br)
  • Medidas eletrofisiológicas (P300) e comportamentais (stroop, digit span, e tempo de reação) foram analisadas em três condições experimentais: placebo 1, placebo 2 e bromazepam. (scielo.br)
  • Method The sample was composed of 15 healthy individuals exposed to three experimental conditions placebo, modafinil and bromazepam . (bvsalud.org)
  • RESUMOObjetivo Investigar e comparar os efeitos neuromoduladores do bromazepam (6mg) e modafinil (200mg), durante a prática de uma tarefa sensoriomotora, analisando as modificações produzidas na potência absoluta de alfa.Método A amostra foi composta por 15 indivíduos saudáveis, expostos a três condições experimentais Placebo , modafinil e bromazepam . (bvsalud.org)
  • posologie bromazepam, bromazepam te koop gevraagd. (skinchat.net)
  • Bromazepam Actavis may be available in the countries listed below. (legitrxscript.com)
  • A 3mg dose of bromazepam is equivalent to a 5mg dose of diazepam . (bionity.com)
  • 1,5mg bromazepam is like 2mg diazepam - strong enough for really old people is all. (drugs-forum.com)
  • Note: 6mg of bromazepam is approximately equivelant to 10mg diazepam. (hajixuk.ru)
  • bromazepam 56mg's ~=10mg diazepam. (hajixuk.ru)
  • Benzodiazepine name voor de stoffen die nordazepam als metaboliet hebben: zoals bijvoorbeeld chloordiazepoxide, clorazepinezuur, diazepam, ketazolam, medazepam en prazepam. (scribd.com)
  • Bij regelmatige inname kan de halfwaardetijd oplopen tot wel 75-100 uur bij diazepam en vergelijkbare benzodiazepinen. (scribd.com)
  • Development and validation of an HPLC method for the simultaneous monitoring of bromazepam and omeprazole. (chuv.ch)
  • He prescribed me to take propranonol, omeprazole and bromazepam. (medhelp.org)
  • Lexaurin (Bromazepam) 3mg has to be stored at a room temperature of not more than 77 degrees F, equivalent to 25 degrees C. It should also be placed in a container which is tightly-closed and without humidity. (viagra-4u.com)
  • Especificamente, os efeitos de 3mg de bromazepam no componente P300 do PRE foram analisados em um experimento duplo-cego. (scielo.br)
  • Os resultados sugerem que os efeitos de 3mg de bromazepam em processos cognitivos não são aparentes. (scielo.br)
  • Apesar do que parece irrefutável na literatura, o bromazepam não produziu efeitos evidentes nas variáveis comportamentais e eletrofisiológicas analisadas. (scielo.br)
  • About albuterol prevacid, ibuprofen of bromazepam of tafil and related to albuterol both antibiotics and benzos, physician's desk reference, levaquin products. (tiscali.cz)
  • Bromazepam is reported to be metabolized by a hepatic enzyme belonging to the Cytochrome P450 family of enzymes. (bionity.com)
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  • Can I drink alcohol while I am taking bromazepam? (mypharmworld.com)
  • We describe a rare case of diffuse macroscopic discoloration and chemical gastritis due to chronic bromazepam intake. (beds.ac.uk)
  • This is the first case in literature that shows a chemical gastritis after bromazepam intake. (beds.ac.uk)
  • Results suggest that the effects of bromazepam (3mg) on cognitive processes are not apparent. (scielo.br)
  • Quantitative study of an acid hydrolysis of bromazepam, which in acidic solution simultaneously undergoes reversible 4,5-azomethine bond cleavage and protolytic reactions, was performed (t = 25degreesC). (ac.rs)
  • While associating the specific exploration paradigm failed to reveal drug side effects, the diverse exploration paradigm revealed but that preference patterns of introverts were influenced by chloramphenicol, while bromazepam sulfate had some no significant effect sensible on the preference patterns of extroverts. (chidsg.com)
  • What sort of side-effects might I get if I am taking bromazepam? (mypharmworld.com)
  • Bioavailability of bromazepam in man after single administration of an oral solution . (page.tl)
  • The present study aimed at investigating the modulatory effects of bromazepam on brain dynamics. (drugs-forum.com)
  • The safety of use of Bromazepam in pregnancy has not been established. (eurdoc.com)
  • Paradoxical effects may also appear after chronic use of bromazepam. (newpharm.store)
  • Bromazepam binds to the GABA receptor GABA A , causing a conformational change and increasing inhibitory effects of GABA. (bionity.com)