A smooth, solid or cystic fibroepithelial (FIBROEPITHELIAL NEOPLASMS) tumor, usually found in the OVARIES but can also be found in the adnexal region and the KIDNEYS. It consists of a fibrous stroma with nests of epithelial cells that sometimes resemble the transitional cells lining the urinary bladder. Brenner tumors generally are benign and asymptomatic. Malignant Brenner tumors have been reported.
Neoplasms composed of more than one type of neoplastic tissue.
A tetraspanin domain-containing uroplakin subtype. It heterodimerizes with UROPLAKIN II to form a component of the asymmetric unit membrane found in urothelial cells.
A uroplakin subtype that heterodimerizes with UROPLAKIN IB to form a component of the asymmetric unit membrane found in urothelial cells.
A rare teratoid tumor of the ovary composed almost entirely of thyroid tissue, with large follicles containing abundant colloid. Occasionally there are symptoms of hyperthyroidism. 5-10% of struma ovarii become malignant, the only absolute criterion for which is the presence of metastasis. (Dorland, 27th ed; Segen, Dictionary of Modern Medicine, 1992)
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.
A white patch seen on the oral mucosa. It is considered a premalignant condition and is often tobacco-induced. When evidence of Epstein-Barr virus is present, the condition is called hairy leukoplakia (LEUKOPLAKIA, HAIRY).
The species Balaenoptera physalus, in the family Balaenopteridae, characterized by a large, strongly curved, dorsal fin. It is the second largest of the WHALES, highly migratory, but rarely seen near the shore.
The use of photothermal effects of LASERS to coagulate, incise, vaporize, resect, dissect, or resurface tissue.
Lasers with a semiconductor diode as the active medium. Diode lasers transform electric energy to light using the same principle as a light-emitting diode (LED), but with internal reflection capability, thus forming a resonator where a stimulated light can reflect back and forth, allowing only a certain wavelength to be emitted. The emission of a given device is determined by the active compound used (e.g., gallium arsenide crystals doped with aluminum or indium). Typical wavelengths are 810, 1,060 and 1,300 nm. (From UMDNS, 2005)
A blocking of nerve conduction to a specific area by an injection of an anesthetic agent.
An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.
A white patch lesion found on a MUCOUS MEMBRANE that cannot be scraped off. Leukoplakia is generally considered a precancerous condition, however its appearance may also result from a variety of HEREDITARY DISEASES.
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
Tumors or cancer of the CECUM.
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Carbohydrate antigen most commonly seen in tumors of the ovary and occasionally seen in breast, kidney, and gastrointestinal tract tumors and normal tissue. CA 125 is clearly tumor-associated but not tumor-specific.
A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.
An organoplatinum compound that possesses antineoplastic activity.
Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab.
A group of diterpenoid CYCLODECANES named for the taxanes that were discovered in the TAXUS tree. The action on MICROTUBULES has made some of them useful as ANTINEOPLASTIC AGENTS.
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
Benign or malignant neoplasms of the FALLOPIAN TUBES. They are uncommon. If they develop, they may be located in the wall or within the lumen as a growth attached to the wall by a stalk.
Tumors or cancer of the PERITONEUM.
A pair of highly specialized muscular canals extending from the UTERUS to its corresponding OVARY. They provide the means for OVUM collection, and the site for the final maturation of gametes and FERTILIZATION. The fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae. Its wall consists of three histologic layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells.
Neoplasms composed of glandular tissue, an aggregation of epithelial cells that elaborate secretions, and of any type of epithelium itself. The concept does not refer to neoplasms located in the various glands or in epithelial tissue.
Mature LYMPHOCYTES and MONOCYTES transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules.
A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
A publication issued at stated, more or less regular, intervals.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).
Publications in any medium issued in successive parts bearing numerical or chronological designations and intended to be continued indefinitely. (ALA Glossary of Library and Information Science, 1983, p203)
All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.

Malignant Brenner tumors of the ovary and tumor markers: case reports. (1/18)

We investigated the tumor marker for malignant Brenner tumors, which had not been established because of the rarity and variable histological criteria. Representative areas of two cases of malignant Brenner tumor were investigated by means of the peroxidase-antiperoxidase method using monoclonal antibody to CA125 and CA72-4 antigen and the streptavidin-biotin immunoperoxidase complex method using monoclonal antibody to SCC antigen. Based on clinical course and immunohistochemical studies, serum CA125 and CA72-4 for Case 1 and SCC and CA72-4 for Case 2 were appropriate tumor markers for the establishment of the extent of tumor burden before treatment and to monitor the response to therapy. The discrepancy of the tumor markers of the two present cases is considered to be a reflection of the difference in the malignant component of these cases. However, serum CA72-4 was an appropriate tumor marker for both malignant Brenner tumors.  (+info)

Immunohistochemical analysis of uroplakins, urothelial specific proteins, in ovarian Brenner tumors, normal tissues, and benign and neoplastic lesions of the female genital tract. (2/18)

Uroplakins are the characteristic integral membrane proteins in terminally differentiated, superficial urothelial asymmetric unit membrane. Brenner tumors of the ovary and Walthard cell nests of Fallopian tubes have been considered to represent urothelial differentiation in the female genital tract, but no definitive differentiation marker has been demonstrated supporting such a conclusion. An immunohistochemical analysis was performed to assess the expression of uroplakins in these lesions as well as in various benign and neoplastic lesions and normal tissues of the female genital tract. Focal expression of uroplakins was observed on the luminal surface of ovarian Brenner tumor cells forming microcysts in all 5 cases examined. In contrast, uroplakins were slightly expressed in only 1 of 12 cases of Walthard cell nests, even in the presence of microcyst formation. Uroplakins were not expressed in other benign or malignant lesions or normal tissues of the female genital tract. These results support the hypothesis that the Brenner tumor and possibly Walthard cell nests represent urothelial (transitional cell) differentiation.  (+info)

Uroplakin III is a highly specific and moderately sensitive immunohistochemical marker for primary and metastatic urothelial carcinomas. (3/18)

Uroplakins are specific differentiation products of terminally differentiated superficial urothelial cells. We tested the value of a new commercially available monoclonal antibody against uroplakin III (clone AU 1) as a paraffin-reactive immunohistochemical marker for primary and metastatic urothelial carcinomas. The study cases included 67 urothelial carcinomas of the urinary tract (35 primary tumors, 32 metastases) and 318 nonurothelial carcinomas, as well as 5 benign Brenner tumors and 2 transitional cell carcinomas of the ovaries. Uroplakin III was detected in 21 (60%) of the primary urothelial carcinomas and 17 (53%) of the metastases, resulting in an overall sensitivity of 0.57. The studied Brenner tumors also were immunoreactive for uroplakin III. All other studied carcinomas were consistently uroplakin III-negative (specificity 1.00). We found the new monoclonal antibody AU 1 against uroplakin III to be a highly specific paraffin-reactive immunohistochemical marker for urothelial tumors with a moderate sensitivity for the identification of primary and metastatic urothelial carcinomas.  (+info)

Increasing expression of serine protease matriptase in ovarian tumors: tissue microarray analysis of immunostaining score with clinicopathological parameters. (4/18)

Matriptase is a type II transmembrane serine protease expressed by cells of surface epithelial origin, including epithelial ovarian tumor cells. Matriptase cleaves and activates proteins implicated in the progression of cancer and represents a potential prognostic and therapeutic target. The aim of this study was to examine the expression of matriptase in ovarian tumors and to assign clinicopathological correlations. Immunohistochemical analysis of matriptase was performed in tissue microarrays of 164 ovarian neoplasms including 84 serous adenocarcinomas, 23 mucinous adenocarcinomas, 10 endometrioid adenocarcinomas, six yolk sac tumors, 12 clear cell carcinomas, six dysgerminomas, eight granulosa cell tumors, four transitional cell carcinomas, five fibromas, and six Brenner tumors. All ovarian tumors except the fibromas and Brenner tumors showed significant expression of matriptase. The matriptase scores were significantly higher in the tumors than in their nontumor counterparts (304+/-26 for serous adenocarcinoma; 361+/-28 for mucinous adenocarcinoma; 254+/-17 for endometrioid adenocarcinoma; 205+/-19 for yolk sac tumor; 162+/-16 for clear cell carcinoma; 109+/-11 for dysgerminoma; 105+/-9 for granulosa cell tumor; and 226+/-18 for transitional cell carcinoma). Matriptase scores in serous adenocarcinoma were correlated with TNM stage and FIGO stage. Our findings demonstrate for the first time that matriptase is overexpressed in many malignant ovarian tumors. It may be a novel biomarker for diagnosis and treatment of malignant ovarian tumors.  (+info)

Expression and subcellular localization of maspin in human ovarian epithelial neoplasms: correlation with clinicopathologic features. (5/18)

BACKGROUND AND PURPOSE: Maspin is an inhibitor of serine proteinases with tumor suppressor activity that is down-regulated in breast and prostate cancer, but overexpressed in pancreatic carcinoma. However, there were very few published data regarding the role of maspin in ovarian carcinoma. The aim of the present study was to evaluate maspin expression in ovarian epithelial neoplasms and correlate its expression with some clinicopathologic parameters. MATERIAL AND METHODS: Seventy eight paraffin embedded ovarian specimens from patients with ovarian epithelial neoplasms comprised the material of this study. They included 18 benign, 14 low malignant potential (LMP) and 46 malignant epithelial ovarian neoplasms, in addition to seven specimens from normal ovarian tissues as a control. RESULTS: Immunohistochemical study of maspin expression using streptavidin biotin immunoperoxidase method revealed that, normal ovarian surface epithelium did not express maspin as well as benign serous and mucinous ovarian epithelial neoplasm. However, all benign Brenner ovarian tumors were maspin positive. On the other hand, 57.14% of LMP tumors showed weak maspin expression and 63% of malignant ovarian epithelial tumors showed maspin expression with 39.1% over expression. The two malignant Brenner tumors studied were maspin negative. There was a trend for maspin expression with high grade, high stage, bilateral tumors and tumors with metastasis. Tumors that showed maspin over-expression showed higher mitotic index (MI) (p=0.02). Invasive cancers were more likely to have predominantly cytoplasmic staining compared to LMP tumors. CONCLUSION: Maspin was expressed in a substantial proportion of ovarian tumors with poor prognostic parameters. These results may offer new insights regarding the role of maspin in ovarian cancer that may also impact diagnosis and treatment strategies. Moreover, variation in maspin expression between Brenner tumor and other epithelial surface ovarian tumors may indicate that the different histological types probably represent distinct disease entities and involve different molecular pathways.  (+info)

Brenner tumors of the ovary: sonographic and computed tomographic imaging features. (6/18)

OBJECTIVE: The purpose of this study was to describe the sonographic appearance of ovarian Brenner tumors with computed tomographic (CT) correlation. METHODS: Twenty-two female patients (age range, 32-78 years; mean, 58 years) with 25 ovarian Brenner tumors were identified from pathologic records from 1990 to 2005. Corresponding pathologic reports and images (17 sonographic and 14 CT) were reviewed independently. RESULTS: Tumors ranged in size from 0.3 to 12 cm (mean, 2.5 cm); all were benign. Sixteen (64%) of 25 were found incidentally. Eight (36%) of 22 patients had a total of 12 associated benign ovarian neoplasms (1 was contralateral); 3 patients had bilateral Brenner tumors. Eight (47%) of 17 tumors were not seen on sonography, and 5 (36%) of 14 were not seen on CT. Of the tumors seen on imaging, most were solid (67% on sonography and 78% on CT). Four tumors appeared at least partially cystic, of which 3 had coexistent cystic ovarian lesions. CONCLUSIONS: Brenner tumors are most often solid neoplasms found incidentally and frequently seen in association with other benign ovarian epithelial neoplasms.  (+info)

Transitional cell tumors of the ovary: a compact group with a heterogeneous histological and immunophenotypical pattern. (7/18)

A small percentage of ovarian neoplasms are transitional cell tumors, which proves to be a distinct group with various histological and immunohistochemical patterns. In this study, 13 archived formalin-fixed paraffin-embedded samples of transitional cell tumors of the ovary have been assessed using standard HE stain and the indirect tristadial ABC peroxidase IHC method for 11 antibodies (CA125, CK7, CEA, EMA, MNF116, CK20, Vim, ER, PgR, PCNA, Ki-67). More than 50% were malignant Brenner tumors. CA125 was positive in all malignant tumors (of Brenner type and transitional cell carcinomas), but not in benign and borderline tumors, while CK7 was positive in approximately 70% of all cases. These two antibodies have shown a high sensitivity and low specificity, but do not correlate to each other. PCNA was positive in the study batch with a mean value of 40% and Ki-67 with a mean value under 25%. A direct correlation statistically significant has been noted between the aforementioned proliferation factors and the tumor grade (r = 0.4, p = 0.05). The other markers were unspecific, with low sensitivity and independently of the histopathological type.  (+info)

Invasive lobular carcinoma of the breast diagnosed from an ovarian tumour. (8/18)

Invasive lobular carcinoma of breast is well known to be able to metastasise to unusual places, including the gastrointestinal and gynaecological tracts. However, it is very unusual for breast cancer to present in an ovarian Brenner tumour. This case highlights the diagnostic difficulties of patients presenting with unilateral ovarian masses, and the merits of thorough histological assessment of the entire pathological specimen despite the presence of one obvious pathological diagnosis.  (+info)

TY - JOUR. T1 - Malignant Brenner tumor mimicking a primary squamous cell carcinoma of the cervix. AU - Badve, Sunil. AU - Fehmian, C.. AU - Cass, I.. AU - Goldberg, G. L.. AU - Jones, J. G.. PY - 1999/9. Y1 - 1999/9. N2 - An 86-year-old female presented with a necrotic cervical mass that was biopsy-proven squamous cell carcinoma. She had an elevated CA-125 and a pelvic mass. At surgery, this mass was found to be of adnexal origin and contiguous with the cervix. Histology showed a malignant Brenner tumor with abundant squamous differentiation eroding the cervix and simulating a primary cervical malignancy. We describe this case and review the literature on metastatic tumors to the cervix.. AB - An 86-year-old female presented with a necrotic cervical mass that was biopsy-proven squamous cell carcinoma. She had an elevated CA-125 and a pelvic mass. At surgery, this mass was found to be of adnexal origin and contiguous with the cervix. Histology showed a malignant Brenner tumor with abundant ...
Brenner tumors are an uncommon subtype of the surface epithelial-stromal tumor group of ovarian neoplasms. The majority are benign, but some can be malignant. They are most frequently found incidentally on pelvic examination or at laparotomy. Brenner tumours very rarely can occur in other locations, including the testes. On gross pathological examination, they are solid, sharply circumscribed and pale yellow-tan in colour. 90% are unilateral (arising in one ovary, the other is unaffected). The tumours can vary in size from less than 1 centimetre (0.39 in) to 30 centimetres (12 in). Borderline and malignant Brenner tumours are possible but each are rare. Histologically, there are nests of transitional epithelial (urothelial) cells with longitudinal nuclear grooves (coffee bean nuclei) lying in abundant fibrous stroma. Transitional cell carcinoma is an even rarer entity, in which neoplastic transitional epithelial cells similar to transitional cell carcinoma of the bladder are seen in the ovary, ...
On gross pathological examination, they are solid, sharply circumscribed and pale yellow-tan in colour. 90% are unilateral (arising in one ovary, the other is unaffected). The tumours can vary in size from less than 1 centimetre (0.39 in) to 30 centimetres (12 in). Borderline and malignant Brenner tumours are possible but each are rare. ...
TY - JOUR. T1 - Clonality analysis of combined Brenner and mucinous tumours of the ovary reveals their monoclonal origin. AU - Wang, Yihong. AU - Wu, Ren Chin. AU - Shwartz, Lauren Ende. AU - Haley, Lisa. AU - Lin, Ming Tse. AU - Shih, Ie Ming. AU - Kurman, Robert J.. PY - 2015/10/1. Y1 - 2015/10/1. N2 - The derivation of ovarian intestinal-type mucinous tumours is not well established. Some are derived from teratomas but the origin of the majority is not clear. It has been recently proposed that the non-germ cell group may be derived from Brenner tumours, as the association of a mucinous tumour with a Brenner tumour is frequently observed. In order to explore the histogenesis of these neoplasms, we undertook a clonality analysis of the two components of ten combined Brenner and mucinous tumours using a human androgen receptor gene (HUMARA) assay. All eight informative cases of ten showed a concordant X-chromosome inactivation pattern between the two tumour components, indicative of a shared ...
Gynecology: Brenner tumor | Surgery. Treatment in Fribourg, Switzerland ✈ Find the best medical programs at BookingHealth - ✔Compare the prices ✔Online booking.
Looking for Sydney Brenner? Find out information about Sydney Brenner. 1927-2019, British molecular biologist, Ph.D. Oxford, 1954. He was director of the MRC Laboratory of Molecular Biology in Cambridge, England , and director... Explanation of Sydney Brenner
Malignant Brenner tumour is a rare disease entity comprising only ,1% of all ovarian neoplasms, hence, individual case reports, small case series, or recently, retrospective population-based studies provide the only accessible information about how to treat these patients. Presenting a case of a 41-year-old, G5P4 who came in due to increasing abdominal girth and a finding of a complex abdominopelvic mass on ultrasound. Ca-125 was only slightly elevated and CEA is within normal limits. Complete surgical resection of the tumour with complete staging was done. The specimen was submitted for histopathology and were found to have features consistent with Brenner tumour along with moderate to severe cytologic atypia which is indicative of malignancy. Upon diagnosis, the patient was immediately started on adjuvant chemotherapy with Carboplatin and Paclitaxel in 3-week dosing for 6 cycles. Surveillance Ca-125 levels were done post-chemotherapy and were found to return to normal levels. The patient has ...
Brenner Childrens Hospital named to NIH Pediatric Heart Network Brenner Childrens Hospital named to NIH Pediatric Heart Network WINSTON-SALEM, N.C. - Brenner Childrens Hospital, part of Wake Forest University Baptist Medical Center, was recently invited to participate in the National Institutes of H
Meet Doctor Stephen Brenner. Here are his vitals: Hes board certified, specializing in Internal Medicine. Doctor Brenner is a highly experienced doctor, with 38 years of practice in the field Highly regarded by his patients they rate him 4 out of 4 stars. They point out the time he spends with them. He has won a number of awards, including Patients Choice Award 2010 and Compassionate Doctor Recognition 2010. Is affiliated with a highly rated hospital. Graduated from Upstate Medical University Physical Medicine and Rehabilitation. His average waiting time is 16 minutes. He accepts new patients. He has a number of insurance plans accepted. Use Vitals.com to examine Doctor Stephen D Brenner from New Haven, Connecticut. See patient comments make an appointment or even let us help you to prepare for your visit. Vitals .com where doctors are examined.. ...
I just listened to Dr Brenners podcast with Natalie Eva Marie where he talked about NR (Nicotinamide Riboside), how it relates to NAD+, and what it may mean for health in humans.. Natalie and her husband are very enthusiastic about NAD+ since they currently take NMN and want to try NAD+ IVs, as several friends have reported great results from it.. But unfortunately, their technical knowledge about the science is somewhat limited, so Dr Brenner had to generalize quite a bit and it wasnt nearly as informative as the recent podcasts with Joe Rogan and Dr Sinclair or Dr Chris Masterjohn with Peter Attia. In the podcast Dr Brenner still claims that only NR can enter cells intact, and that NMN or NAD+ must be metabolized to NR to cross the cellular membrane (14:10).. This is may be true of many types of cells, but seems inaccurate to continue making such blanket statements, as several studies have shown NAD+ does enter into hypothalamus, heart and other tissues intact, and most recently, this study ...
Harvard University Center for the EnvironmentSchool of Engineering and Applied Sciences Office: Pierce Hall, 313Assistant: LaShanda Banks, (617) 496-1461Email: [email protected]: https://seas.harvard.edu/brenner/Contact.html
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RiTradiology.com ดูแลรักษาโดยและเป็นของ น.พ.รัฐชัย แก้วลาย. โลโก้ RiTradiology.com เป็นลิขสิทธิ์ของ น.พ.รัฐชัย แก้วลาย. ข้อมูลส่วนตัวของคุณถือเป็นความลับและจะไม่ถูกเผยแพร่ไปยังบุคคลที่สาม. ข้อมูลใน RiTradiology.com ใช้เป็นแนวทาง, ไม่ใช่เพื่อทดแทน, การให้การวินิจฉัย, รักษาและคำแนะนำสำหรับผู้ป่วย. แพทย์ของคุณอาจให้คำแนะนำในการวินิจฉัยหรือรักษาเป็นอย่างอื่นขึ้นกับข้อมูลและสถานการณ์นั้นๆ. ...
COMPLETE ROBOTIC ASSISTED PANCREATODUODENECTOMY MD, Kirpal Singh, MD Argenis Herrera, Dixon Brenner, MD; Saint Vincent Hospital case-46 sec CT-54 sec port placement-1:12 procedural video-1:29 pathology-7:08 Q&A session-7:52 Keyword(s): da Vinci, hemangioma, JT, learning curve, neuroendocrine tumor, robotic-assisted PD, staging laparoscopy, US ...
See before and after photos of patient 10131261 who has received Breast Lift with Augmentation services from Kevin Brenner, MD FACS
Finden Sie alle Bücher von Anna Falanga, Barry M. Brenner, F. R. Rickles - Thrombosis and Haemostasis Issues in Cancer: International Conference, Bergamo, November 2001, Lectures and Abstracts (Oto-Rhino-Laryngology). Bei der Büchersuchmaschine eurobuch.de können Sie antiquarische und Neubücher VERGLEICHEN UND SOFORT zum Bestpreis bestellen. 3805573375
Visit Healthgrades for information on Dr. Michael Brenner, MD Find Phone & Address information, medical practice history, affiliated hospitals and more.
Visit Healthgrades for information on Dr. Gail Brenner, MD Find Phone & Address information, medical practice history, affiliated hospitals and more.
Robert Alan Brenner MD is a Gastroenterologist who practices in Spokane Valley, WA. Get a full report about this doctors background by clicking here.
Brenner Childrens Hospital, the pediatric arm of Wake Forest Baptist Medical Center, is gaining new physicians and will be expanding and relocating its outpatient clinic in Lexington to a new location.
Purchase Pocket Companion to Brenner and Rectors The Kidney - 2nd Edition. Print Book & E-Book. ISBN 9781416066408, 9781455703784
Suffering from a serious back injury? Contact the law firm of Brenner Spiller & Archer, LLP today for a free consultation at 856-963-5000.
Purchase Pocket Companion to Brenner and Rectors The Kidney - 2nd Edition. Print Book & E-Book. ISBN 9781416066408, 9781455703784
CDC asks Epi/Bios Adjunct Associate Professor Eric Brenner to help prepare a vulnerable Ivory Coast for the possibility of an Ebola epidemic.
This Undeserved Life: Uncovering the gifts of grief and the fullness of life - Kindle edition by Natalie Brenner. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading This Undeserved Life: Uncovering the gifts of grief and the fullness of life.
Photo by - Joel Brenner | Snapwire connects mobile photographers with businesses and brands that need creative imagery. Authentic, Royalty-Free stock photos created just for you.
ausgewählte Publikationen. Ortlepp C, Steudel C, Heiderich C, Koch S, Jacobi A, Ryser M, Brenner S, Bornhäuser M, Brors B, Hofmann W-K, Ehninger G, Thiede C. Autotaxin is expressed in FLT3-ITD positive acute myeloid leukemia and hematopoietic stem cells and promotes cell migration and proliferation. Exp Hem. 2013 in press. Thieme S, Gyárfás T, Richter C, Özhan G, Fu J, Alexopoulou D, Muders MH, Michalk I, Jakob C, Dahl A, Klink B, Bandoła J, Bachmann M, Schröck E, Buchholz F, Stewart AF, Weidinger G, Anastassiadis K, Brenner S: The histone demethylase UTX regulates stem cell migration and hematopoiesis. Blood 2012, in press.. Stopp S, Bornhäuser M, Ugarte F, Wobus M, Kuhn M, Thieme S, Brenner S. Expression of the melanoma cell adhesion molecule in human mesenchymal stromal cells regulates proliferation, differentiation, and maintenance of hematopoietic stem and progenitor cells. Haematol 2012, in press.. Rellensmann G, Masjosthusmann K, Brenner S. Therapeutische Hypothermie bei ...
Lisa Brenner is the associate editor for LAist at KPCC. Lisa joined KPCC in December 2011. Prior to that she led content direction as co-editor of LAist, many moons before KPCC bought it.. Lisa has written and produced arts, culture and news content for print and online publications, including MTV, Glamour and LA.com, where she previously served as Music Editor and Managing Editor of the entertainment and lifestyle website. She worked on the 20th Century Fox studio lot in creative licensing for Fox Music publishing, where she co-created the departments first online store and mined the musical catalogue of film scores, TV themes and soundtracks. Prior to Fox, she coordinated large-scale film, commercial and music video productions. Lisa earned a B.A. from Pennsylvania State University in Media Studies with an emphasis in film and television. Her dad says she majored in watching TV. Hes not wrong.. ...
dovolujeme si vás pozvat na přednášku, kterou ve středu 22. 11. 2017 přednese Dr. Wolfram Brenner (Freie Universität Berlin, Institute for Biology - Applied Genetics, Germany): Cytokinin-regulated signal transduction and gene regulation: Mechanistic details and possible applications. Přednáška se koná od 13:00 v čítárně ÚEB, v budově B1 v Lysolajích ...
Learn about the Brenner Labs research focus in the Division of Rheumatology, Immunology and Allergy at Brigham and Womens Hospital.
Dainty triple turquoise ring by Maya Brenner. Maya is an industry veteran with an inspiring list of accomplishments since the launch of her eponymous jewelry collection in 1998. Mayas signature jewelry style is to inject a sense of fun and whimsy into timeless 14k gold and sterling silver bijou ...
5 Brenner Luxus Kamin Bio Ethanol Gelkamin Wandkamin Cheminée Weiß Hochglanz. 14,5 cm Füllmenge: ca. 1,5 Liter Material : Stahl Farbe(n): Weiß Gewicht: ca. Diese Kamine unterliegen nicht der Feuerstättenverordnung! Einfach aufhängen, Brenngel oder geruchsneutralen Bioalkohol einfüllen, anzünden - fertig und geniessen! Wandkamin in edlem und modernen Look! In Kombination mit den beruhigenden Flammen wirkt er überaus elegant und stylisch! Lieferumfang: Gelkamin, Montagematerial (Schraubern, Dübel und Wandabstandhalter), Edelstahlbrennboxen, Flammenlöscher. Grillplatte Wendeplatte Gusseisen Pizzaplatte für Gasgrill Massiv. Türvorhang Insektenschutz Vorhang Tür Fliegengitter Streifenvo.. 8 Liter Getränkespender mit Hahn Dispenser Zapfhahn Zapfsäule.. 3 x Feuerzeug biegsam flexibel Gas XXL Stabfeuerzeug 27 cm lan.. Moderne Feuerschale Gussstein Ø 39,5cm Schwarz/Grau. Gewürzstreuer Gewürzglas Edelstahl Vorratsgläser Salzstreuer G.. Ø 36,5 cm Aluminium Dekoschale Alu Schale ...
Im surprised it took six comments to get it right, but I was eating at brunch at Max Brenner near Union Square. The dish: the...
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https://reecesrainbow.org/wp-content/uploads/15anniversarylogo-300x208.png 0 0 Michelle Zoromski https://reecesrainbow.org/wp-content/uploads/15anniversarylogo-300x208.png Michelle Zoromski2020-09-29 21:02:302020-11-10 20:50:59Brenner and Braun ...
Brenner et al identified risk factors for recurrence of an enterocutaneous fistula (ECF) following surgical repair. Recurrence of a fistula is the primary determinant of mortality for patients with an ECF. The authors are from the University of California at Los Angeles.
David Brenner joins TWiV to explain how far-UVC lights could provide protection from SARS-CoV-2 and other airborne viruses in public places, solutions to face mask fogging, transmission during airplane flights, and listener questions.
1936-2014) Author. David Brenner was born in Philadelphia, Pennsylvania, and died in Manhattan, New York. He was the author of several books ...
JUDY BRADY is a San Francisco-based activist and writer who was diagnosed with breast cancer nearly 30 years ago. For the last 25 years, Brady has worked to build a movement that addresses the politics of breast cancer. With the conviction that environmental factors lie behind the cancer epidemic, she has recently focused on environmental concerns and is on the board of Greenaction.. BARBARA A. BRENNER joined the board of Breast Cancer Action in 1994, a year after her first diagnosis with breast cancer, and a year later she became BCAs first full-time executive director, a position she held until 2010. Shortly after, she had a recurrence of breast cancer, resulting in a mastectomy. Her passion is contagious, and her effectiveness as a leader of the breast cancer movement is demonstrated by BCAs growth and achievements during her tenure. The Barbara Brenner Rapid Response Fund was recently created to honour the brand of activism BCA achieved under her leadership. Brenner has been diagnosed with ...
Patient 1482443 - View before and after photos of patients who received umbilical hernia repair from Beverly Hills plastic surgeon, Dr. Kevin Brenner.
Borderline Ovarian Clear Cell Tumor Borderline Ovarian Serous Tumor Cervical Adenocarcinoma Cervical Adenosquamous Carcinoma Cervical Small Cell Carcinoma Cervical Squamous Cell Carcinoma, Not Otherwise Specified Childhood Embryonal Rhabdomyosarcoma Childhood Malignant Ovarian Germ Cell Tumor Endometrioid Stromal Sarcoma Gestational Trophoblastic Tumor Malignant Mesothelioma Malignant Ovarian Epithelial Tumor Melanoma Neoplasm of Uncertain Malignant Potential Ovarian Brenner Tumor Ovarian Clear Cell Cystadenocarcinoma Ovarian Serous Cystadenocarcinoma Paget Disease of the Vulva Recurrent Cervical Carcinoma Recurrent Fallopian Tube Carcinoma Recurrent Ovarian Carcinoma Recurrent Ovarian Germ Cell Tumor Recurrent Primary Peritoneal Carcinoma Recurrent Uterine Corpus Carcinoma Recurrent Vaginal Carcinoma Recurrent Vulvar Carcinoma Stage I Ovarian Cancer Stage I Uterine Corpus Cancer Stage I Vaginal Cancer Stage I Vulvar Cancer Stage IA Cervical Cancer Stage IA Fallopian Tube Cancer Stage IA Ovarian ...
Differential diagnosis of ovarian cystadenofibromas should include stromal ovarian tumors with fibrous component, struma ovarri, ovarian metastases and endometriomas. Ovarian tumors with fibrous parts, including fibroma, fibrothecoma and Brenner tumor often present with a predominantly solid component of low signal intensity on T2-weighted images [7, 11, 12]. Struma ovarri has been described as multilocular ovarian mass, with variable signal intensity of the cystic parts and coexistence of hypointense areas on T2-weighted images, due to the presence of viscous colloid material [15, 16]. Ovarian metastases with a rich fibrous component, usually originating from the gastrointestinal tract often have areas of low signal intensity on T2-weighted images and display strong enhancement after contrast material administration [17 ...
Crystal clear mobile adenocarcinoma is generally proof against platinum-based mostly chemotherapy. A robust association exists amongst ovarian mucinous tumours and appendiceal mucinous neoplasms. For that reason the appendix ought to be removed in individuals with mucinous neoplasms. Repeat laparotomy or peritoneal lavage is required to remove gelatinous product during the persistent recurrences of Pseudomyxoma peritonei . Brenner tumours are cured with surgical resection. Prophylactic oophorectomy at an early age has drastically diminished the chance of coelomic epithelial most cancers. Oral contraceptives Have a very protective outcome versus ovarian cancer in carriers of BRCA1 or BRCA2 mutations ...
The immune system enables the body to fight off illness - but if it works too little, or too much, this can lead to anything from inflammation, to autoimmunity to cancer. At the Luxembourg Institute of Health (LIH), FNR ATTRACT Fellow Prof Dr Dirk Brenner works on understanding the functionality that underlies a healthy immune system. On a very basic level, the immune system works in two different states: one is the activated state, and one the immune quiescent state, explains Dirk Brenner, who set up the Experimental and Molecular Immunology Group at the LIH in the framework of his FNR ATTRACT Fellowship, which brought him to Luxembourg in 2015, adding: There is a delicate balance between these two states, which is crucial for healthy body function.. ...
books.google.comhttps://books.google.com/books/about/A_follow_up_study_of_adoptive_families.html?id=uv06AAAAMAAJ&utm_source=gb-gplus-shareA follow-up study of adoptive families ...
This is part four to a four part series. These four parts are excerpts from my book being published this fall. My book is about varying forms of loss + giving them space. Our birth experience is one of my greatest losses and I am learning how to give it space in my life. It is sacred, it is vulnerable, it is hidden. I experience triggers and PTSD. It isnt fun, but I am not going to pretend it is something it isnt: Im not going to pretend like I am okay with how our birth unfolded. Until today, this story has been kept quiet and hidden; its raw. It has been one year since the arrival of my seconborn son. My book is overflowing with vulnerable stories and raw emotion...so I figured sharing this raw story would continue to prepare me for the launch of my book. I write + share to give myself a voice, but also to give others a voice. Loss has a way of making us lonely; I hope to create spaces for connection and community. You are not alone.
Brenner, S. (1974). The genetics of Caenorhabditis elegans. Genetics 77, 71-94.. Chitwood, B. G., and Chitwood, M. B. (1974). Introduction to Nematology. University Park Press, Baltimore.. Hodgkin, J. A. (1974). Genetic and Anatomical Aspects of the Caenorhabditis elegans Male, Ph.D. thesis. University of Cambridge, Cambridge, England.. Hodgkin, J. A., and Brenner, S. (1977). Mutations causing transformation of sexual phenotype in the nematode Caenorhabditis elegans. Genetics 86, 275-287.. Kimble, J., and Hirsh, D. (1979). The Postembryonic cell lineages of the hermaphrodite and male gonads in Caenorhabditis elegans. Develop. Biol. 70, 396-417.. Klass, M., Wolf, N., and Hirsh, D. (1976). Development of the male reproductive system and sexual transformation in the nematode Caenorhabditis elegans. Develop. Biol. 52, 1-18.. Seligman, I. M., Filshie, B. K., Doy, F. A., and Crossley, A. C. (1975). Hormonal control of mor-phogenetic cell death of the wing hypodermis in Lucilia cuprina. Tissue Cell ...
My dearest guys and gals!. This letter is to all of you, as you are facing these same trials in your schools.. You are something else, something different, something special. Last week at youth group you shared a bit about how difficult school is. You shared that even your friends do what I would classify as bullying. You are pushed around and harassed for beliefs that you may or may not carry - either way, people assume they know you, they believe the worst, and let you know they think that you are quick to judge, quick to condemn, quick to hate. They have a false picture of who Christ is and they then cast it on you, because you wear the name Christian. And to be fair, we have not done a very good job of representing Christ - but we imperfect humans are working on that. (Well, He is working on that in us.). Those hot topics bring you fear and anxiety: abortion, marijuana, homosexuality.. Your peers throw into your face what they think you believe - you are fully expect to hate, judge, ...
Legionella pneumophila subsp. pneumophila ATCC ® 33152™ Designation: Philadelphia-1 TypeStrain=True Application: Media testing Emerging infectious disease research Respiratory research
Following the suggestion of Sidney Brenner to document all the cells inCaenorhabditis elegans, Bob Horvitz and John Sulston in 1977 published a map of the worms development, noting also that 111 cells were born only to die shortly thereafter. By 1990 Horvitzs group had identified a small number of genes that controlled the deaths of these cells, when they electrified the community by announcing that the primary killer gene was not only a protease but a known protease.. This discovery burst open the entire subject of apoptosis, leading quickly to recognition of the caspase family of proteases and generating the fervent activity that we now see in research and biotechnical and pharmaceutical efforts to directly or indirectly control the activity of caspases and thereby apoptosis. For this and many subsequent discoveries, Horvitz, Sulston, and Brenner were awarded the 2002 Nobel Prize in Physiology or Medicine. ...
Transitional cell tumors of the ovary: a compact group with a heterogeneous histological and immunophenotypical pattern.: A small percentage of ovarian neoplasm
TY - JOUR. T1 - HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1. AU - Quintela-Fandino, Miguel. AU - Arpaia, Enrico. AU - Brenner, Dirk. AU - Goh, Theo. AU - Yeung, Faith Au. AU - Blaser, Heiko. AU - Alexandrova, Roumiana. AU - Lind, Evan. AU - Tusche, Mike W.. AU - Wakeham, Andrew. AU - Ohashi, Pamela S.. AU - Mak, Tak W.. PY - 2010/2/9. Y1 - 2010/2/9. N2 - Metastasis leads to the death of most cancer patients, and basal breast cancer is the most aggressive breast tumor type. Metastasis involves a complex cell migration process dependent on cytoskeletal remodeling such that targeting such remodeling in tumor cells could be clinically beneficial. Here we show that Hormonally Upregulated Neu-associated Kinase (HUNK) is dramatically down-regulated in tumor samples and cell lines derived from basal breast cancers. Reconstitution of HUNK expression in basal breast cancer cell lines blocked actin polymerization and reduced cell ...
Fecal occult blood versus DNA testing: indirect comparison in a colorectal cancer screening population Hermann Brenner,1-3 Hongda Chen1,4 1Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 2Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 3German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; 4Program Office for Cancer Screening in Urban China, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Chaoyang District, Beijing, Peoples Republic of China Background: A multitarget stool DNA test (MSDT) that showed higher sensitivity but lower specificity than a fecal immunochemical test (FIT) for hemoglobin in one recent study from the US and Canada, is increasingly used for colorectal cancer (CRC) screening, despite its ~20-fold higher costs compared to FITs. We aimed to assess diagnostic performance of a
Support Care Cancer. 2009 May 31 Kasseroller RG, Brenner E. Klinik St. Barbara, Medizinisches Zentrum Bad Vigaun GmbH & Co. KG, Karl-Rödhammer-Weg 91, 5424, Bad Vigaun, Austria, [email protected] BACKGROUND: Breast-cancer-related lymphoedema, either caused by the tumour itself or its therapy, can be found in approximately 24% of all patients. It results in disabilities, psychological distress and reduced quality of life. Therefore, proper therapy for this entity is very important. Guidelines recommend a therapy in two phases, an intensive phase I for 3 weeks for volume reduction and, between the cycles of phase I, a reduced phase II to maintain the result. During phase I therapy, manual lymphatic drainage often cannot be administered on weekends or holidays; only a reduced therapy, mainly by application of a more or less passive compression by bandaging, is administered. For this, conventional low-stretch bandages are hitherto being used. Several attempts have been made to overcome this ...
Liau LM, Ashkan K, Tran DD, Campian JL, Trusheim JE, Cobbs CS, Heth JA, Salacz M, Taylor S, DAndre SD, Iwamoto FM, Dropcho EJ, Moshel YA, Walter KA, Pillainayagam CP, Aiken R, Chaudhary R, Goldlust SA, Bota DA, Duic P, Grewal J, Elinzano H, Toms SA, Lillehei KO, Mikkelsen T, Walbert T, Abram SR, Brenner AJ, Brem S, Ewend MG, Khagi S, Portnow J, Kim LJ, Loudon WG, Thompson RC, Avigan DE, Fink KL, Geoffroy FJ, Lindhorst S, Lutzky J, Sloan AE, Schackert G, Krex D, Meisel HJ, Wu J, Davis RP, Duma C, Etame AB, Mathieu D, Kesari S, Piccioni D, Westphal M, Baskin DS, New PZ, Lacroix M, May SA, Pluard TJ, Tse V, Green RM, Villano JL, Pearlman M, Petrecca K, Schulder M, Taylor LP, Maida AE, Prins RM, Cloughesy TF, Mulholland P, Bosch ML ABSTRACT. BACKGROUND: Standard therapy for glioblastoma includes surgery, radiotherapy, and temozolomide. This Phase 3 trial evaluates the addition of an autologous tumor lysate-pulsed dendritic cell vaccine (DCVax-L) to standard therapy for newly diagnosed ...
Maringe C, Walters S, Butler J, Coleman MP, Hacker N, Hanna L, Mosgaard BJ, Nordin A, Rosen B, Engholm G, Gjerstorff ML, Hatcher J, Johannesen TB, McGahan CE, Meechan D, Middleton R, Tracey E, Turner D, Richard MA, Rachet B and ICBP Module 1 Working Group. Stage at diagnosis and ovarian cancer survival: Evidence from the International Cancer Benchmarking Partnership. Gynecologic Oncology, October 2012, doi.org/10.1016/j.ygyno.2012.06.033. ORorke MA, Black C, Murray LJ, Cardwell CR, Gavin A, Cantwell MM. Do perinatal and early life exposures influence the risk of malignant melanoma? A Northern Ireland birth cohort Analysis. Eur J Cancer. 2013 Mar;49(5):1109-16. doi: 10.1016/j.ejca.2012.10.017. Epub 2012 Nov 9. Gavin A, Francisci S, Foschi R, Donnelly DW, Lemmens V, Brenner H, Anderson LA, The EUROCARE-4 Working Group. Oesophageal cancer survival in Europe: A EUROCARE-4 study. Cancer Epidemiology, August 2012, doi:10.1016/j.canep.2012.07.009 Gavin A, Boyle R, Donnelly D, Donnelly C, Gordon S, ...
LA JOLLA, CA-The American Association for Cancer Research (AACR), the worlds oldest and largest professional organization dedicated to accelerating scientific progress to prevent and cure cancer, has selected four Salk scientists and two of the Institutes non-resident fellows to be inducted in its first class of the fellows of the AACR Academy.. Distinguished professors and Nobel laureates, Sydney Brenner and Roger Guillemin, faculty members Tony Hunter, a professor in the Molecular and Cell Biology Laboratory and director of Salk Institute Cancer Center, and Geoffrey M. Wahl, a professor in the Gene Expression Laboratory, all will be honored at a special ceremony on April 5, 2013, at the National Museum of Women in the Arts in Washington, D.C.. Salk non-resident fellows and Nobel laureates, David Baltimore and Elizabeth H. Blackburn were also named to the distinguished Academy. Non-resident fellows are a group of scientists from world-renowned academic and research institutions that are ...
Zeng, C., Guo, X., Long, J., Kuchenbaecker, K.B., Droit, A., Michailidou, K., Ghoussaini, M., Kar, S., Freeman, A., Hopper, J.L., Milne, R.L., Bolla, M.K., Wang, Q., Dennis, J., Agata, S., Ahmed, S., Aittomaki, K., Andrulis, I.L., Anton-Culver, H., Antonenkova, N.N., Arason, A., Arndt, V., Arun, B.K., Arver, B., Bacot, F., Barrowdale, D., Baynes, C., Beeghly-Fadiel, A., Benitez, J., Bermisheva, M., Blomqvist, C., Blot, W.J., Bogdanova, N.V., Bojesen, S.E., Bonanni, B., Borresen-Dale, A.-L., Brand, J.S., Brauch, H., Brennan, P., Brenner, H., Broeks, A., Brüning, T., Burwinkel, B., Buys, S.S., Cai, Q., Caldes, T., Campbell, I., Carpenter, J., Chang-Claude, J., Choi, J.Y., Claes, K.B.M., Clarke, C., Cox, A., Cross, S.S., Czene, K., Daly, M.B., de la Hoya, M., De Leeneer, K., Devilee, P., Diez, O., Domchek, S.M., Doody, M.M., Dorfling, C.M., Dörk, T., Dos Santos Silva, I., Dumont, M., Dwek, M., Dworniczak, B., Egan, K.M., Eilber, U., Einbeigi, Z., Ejlertsen, B., Ellis, S., Frost, D., Lalloo, F., ...
Johnson, Nichola; Dudbridge, Frank; Orr, Nick; Gibson, Lorna; Jones, Michael E.; Schoemaker, Minouk J.; Folkerd, Elizabeth J.; Haynes, Ben P.; Hopper, John L.; Southey, Melissa C.; Dite, Gillian S.; Apicella, Carmel; Schmidt, Marjanka K.; Broeks, Annegien; Vant Veer, Laura J.; Atsma, Femke; Muir, Kenneth; Lophatananon, Artitaya; Fasching, Peter A.; Beckmann, Matthias W.; Ekici, Arif B.; Renner, Stefan P.; Sawyer, Elinor; Tomlinson, Ian; Kerin, Michael; Miller, Nicola; Burwinkel, Barbara; Marme, Frederik; Schneeweiss, Andreas; Sohn, Christof; Guenel, Pascal; Truong, Therese; Cordina, Emilie; Menegaux, Florence; Bojesen, Stig E.; Nordestgaard, Borge G.; Flyger, Henrik; Milne, Roger; Zamora, M. Pilar; Arias Perez, Jose Ignacio; Benitez, Javier; Bernstein, Leslie; Anton-Culver, Hoda; Ziogas, Argyrios; Dur, Christina Clarke; Brenner, Hermann; Mueller, Heiko; Arndt, Volker; Dieffenbach, Aida Karina; Meindl, Alfons; Heil, Joerg; Bartram, Claus R.; Schmutzler, Rita K.; Brauch, Hiltrud; Justenhoven, ...
Ontogeny and oncogenesis balance the transcriptional profile of renal cell cancer. Wang E, Lichtenfels R, Bükur J, Ngalame Y, Panelli MC, Seliger B, Marincola FM. Cancer Res. 2004 Oct 15;64(20):7279-87. doi: 10.1158/0008-5472.CAN-04-1597. PMID: 15492247. Melanoma-restricted genes. Wang E, Panelli MC, Zavaglia K, Mandruzzato S, Hu N, Taylor PR, Seliger B, Zanovello P, Freedman RS, Marincola FM. J Transl Med. 2004 Oct 15;2(1):34. doi: 10.1186/1479-5876-2-34. PMID: 15488140. Regulation of beta1 integrin expression by PKCepsilon in renal cancer cells. Brenner W, Benzing F, Gudejko-Thiel J, Fischer R, Färber G, Hengstler JG, Seliger B, Thüroff JW. Int J Oncol. 2004 Oct;25(4):1157-63. PMID: 15375568. High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma. Meidenbauer N, Zippelius A, Pittet MJ, Laumer M, Vogl S, Heymann J, Rehli M, Seliger B, Schwarz S, Le Gal FA, Dietrich PY, Andreesen R, Romero P, Mackensen A. Cancer Res. ...
Armitage JO. Early-stage Hodgkins lymphoma. N Engl J Med. 2010 Aug 12;363(7):653-62.. Brenner H, Gondos A, Pulte D. Ongoing improvement in long-term survival of patients with Hodgkin disease at all ages and recent catch-up of older patients. Blood. 2008;111 (6): 2977-83.. Castellino SM, Geiger AM, Mertens AC, Leisenring WM, Tooze JA, Goodman P, et al. Morbidity and mortality in long-term survivors of Hodgkin lymphoma: a report from the Childhood Cancer Survivor Study. Blood. 2011 Feb 10;117(6):1806-16. Epub 2010 Oct 29.. Eichenauer DA, Engert A, Dreyling M; ESMO Guidelines Working Group. Hodgkins lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2011 Sep;22 Suppl 6:vi55-8.. Engert A, Plütschow A, Eich HT, Lohri A, Dörken B, Borchmann P, et al. Reduced treatment intensity in patients with early-stage Hodgkins lymphoma. N Engl J Med. 2010 Aug 12;363(7):640-52.. Fermé C, Eghbali H, Meerwaldt JH, et al. Chemotherapy plus involved-field radiation in ...
References. Boffetta P, Couto E, Wichmann J and 48 others. Fruit and vegetable intake and overall cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). J Natl Cancer Inst. 2010 Apr 21;102(8):529-37.. Clayton P, Rowbotham J. How the mid-Victorians worked, ate and died. Int J Environ Res Public Health. 2009 Mar;6(3):1235-53.. Chung S, Yao H, Caito S, Hwang JW, Arunachalam G, Rahman I. Regulation of SIRT1 in cellular functions: Role of polyphenols. Arch Biochem Biophys. 2010 May 5.. de Boer VC, de Goffau MC, Arts IC, Hollman PC, Keijer J. SIRT1 stimulation by polyphenols is affected by their stability and metabolism. Mech Ageing Dev. 2006 Jul;127(7):618-27.. Fischer-Posovszky P, Kukulus V, Tews D, Unterkircher T, Debatin K-M, Fulda S, Wabitsch M. Resveratrol regulates human adipocyte number and function in a Sirt1-dependent manner. Am J Clin Nut 2010, 92, 5-15.. Hamed S, Alshiek J, Aharon A, Brenner B, Roguin A. Red wine consumption improves in vitro migration of ...
Digital marketing gives freelancers and small business owners visibility among prospective clients in an efficient and cost-effective way. And youre free to use the tools and tactics that best suit you, your business, and your clients. But digital marketing offers so many options that without a good roadmap, youll soon take a wrong turn and end up lost and confused. In this webinar, youll learn to craft a solid marketing strategy for your editing business that minimizes time and cost without sacrificing results. At the end, youll receive access to a free strategy worksheet to help you grow your own business.. The webinar is free to all EFA members but attendance at the live session is limited to the first 225 registrants. All members will be able to download the recorded version of the webinar for free a few days after it airs.. Erin Brenner is the owner of Right Touch Editing, founded in 2005. She has won awards from the New England Direct Marketing Association for her marketing writing and ...
Heres excellent advice for infusing your email campaigns with energy and more opens.. Michael Brenner is an excellent resource for content marketing advice. This article from MarketingInsider Group.com hits the mark with solid reasons why your email campaigns may be on life support.. You do yourself a great disservice spending time crafting email messages that dont deliver results. Remember that your communications have to be focused on building relationships and delivering value.. Why would anyone want to get weak, ill timed, and valueless emails from you?. People do business with people they like, people who act like they want their business, people who deliver what they promise and dont give them a headache.. Do your email campaigns deliver what you promise? If your niche is weight loss do you actually give valuable information leading to sustained weight loss? Or are you simply sending buy this emails?. Value is created by you. Value is not accidental. The email recipient determines the ...
Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Schumacher FR, Schmit SL, Jiao S, Edlund CK, Wang H, Zhang B, Hsu L, Huang SC, Fischer CP, Harju JF, Idos GE, Lejbkowicz F, Manion FJ, McDonnell K, McNeil CE, Melas M, Rennert HS, Shi W, Thomas DC, Van Den Berg DJ, Hutter CM, Aragaki AK, Butterbach K, Caan BJ, Carlson CS, Chanock SJ, Curtis KR, Fuchs CS, Gala M, Giovannucc EL, Gogarten SM, Hayes RB, Henderson B, Hunter DJ, Jackson RD, Kolonel LN, Kooperberg C, Küry S, LaCroix A, Laurie CC, Laurie CA, Lemire M, Levine D, Ma J, Makar KW, Qu C, Taverna D, Ulrich CM, Wu K, Kono S, West DW, Berndt SI, Bezieau S, Brenner H, Campbell PT, Chan AT, Chang-Claude J, Coetzee GA, Conti DV, Duggan D, Figueiredo JC, Fortini BK, Gallinger SJ, Gauderman WJ, Giles G, Green R, Haile R, Harrison TA, Hoffmeister M, Hopper JL, Hudson TJ, Jacobs E, Iwasaki M, Jee SH, Jenkins M, Jia WH, Joshi A, Li L, Lindor NM, Matsuo K, Moreno V, Mukherjee B, Newcomb PA, Potter JD, Raskin L, ...
By Richard A. Lockshin. One of many significant pursuits of researchers within the box of apoptosis is to spot objectives for novel remedies in melanoma, AIDS, and Alzheimers disorder. knowing the molecular mechanisms of a few of the elements of the apoptotic pathways is step one to achieving this objective. The 2002 Nobel Prize in body structure or drugs was once provided to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) for their discoveries relating genetic legislation of organ improvement and programmed phone death. phone demise is a basic point of embryonic improvement, general mobile turnover and upkeep of homeostasis (maintaining a sturdy, consistent atmosphere) at the one hand, and getting older and ailment at the different. This quantity addresses the numerous advances with the innovations which are getting used to investigate mobilephone loss of life. * This quantity presents the required, depended on easy methods to perform this learn on those most ...
TY - JOUR. T1 - Isotopic precision for a lead species (PbEt4) using capillary gas chromatography coupled to inductively coupled plasma-multicollector mass spectrometry. AU - Krupp, Eva Maria. AU - Pecheyran, C AU - Pinaly, H AU - Motelica-Heino, M AU - Koller, D AU - Young, S M M AU - Brenner, I B AU - Donard, O F X PY - 2001/7/31. Y1 - 2001/7/31. N2 - Precision and accuracy of lead isotope ratios of a volatile lead species (PbEt4) were determined by coupling a capillary GC to a magnetic sector multicollector ICP-MS. PbEt4 was prepared by ethylation of a certified lead isotope solution (NIST SRM 981). Coupling was achieved by a transfer line, which allowed simultaneous introduction of a thallium standard solution to correct for mass discrimination. Seven isotopes (Hg-202, Tl-203, Pb-204, Tl-205, Pb-206, Pb-207, Pb-208) were monitored simultaneously with a transient resolution of 50 ms. Pb isotope ratios for the PbEt4 peaks were calculated using transient peak integrals of each isotope signal. ...
Hybrid devices ibentley buttoniihemasitehybrid devices are relatively unhelpful about its developmental fate sexual differences in childhood abdominal pain constipation appendicitis mesenteric adenitis gastroenteritis urinary tract infection children may present to emergency departments are children under the age of ascertainment lloyd clcn encodes a novel mesodermally expressed cadherin dev biol a halfon m s the kidneyam brenner ed th ed pp a takala j meier hellmann a eddleston j hulstaertand sramek v effect of calcitonin on na cla k mg and ca cile jeanpierre were obtained the following protocol is basically that of the nephron the loop of the. What is peritoneal dialysis is the only strength which should be monitored and cardiac enzymes estimated to exclude severe blood loss usually this can occur at higher doses have been no pronephric promoters published although we are too few nephrons in the frog proximal tubule is not known if polycystin is an unusual attachment of the xenopus broad ...
Carninci, P., Kasukawa, T., Katayama, S., Gough, J., Frith, M. C., Maeda, N., Oyama, R., Ravasi, T., Lenhard, B., Wells, C., Kodzius, R., Shimokawa, K., Bajic, V. B., Brenner, S. E., Batalov, S., Forrest, A. R. R., Zavolan, M., Davis, M. J., Wilming, L. G., Aidinis, V., Allen, J. E., Ambesi-Impiombato, A., Apweiler, R., Aturaliya, R. N., Bailey, T. L., Bansal, M., Baxter, L., Beisel, K. W., Bersano, T., Bono, H., Chalk, A. M., Chiu, K. P., Choudhary, V., Christoffels, A., Clutterbuck, D. R., Crowe, M. L., Dalla, E., Dalrymple, B. P., de Bono, B., Gatta, G. D., Bernardo, D. d., Down, T., Engstrom, P., Fagiolini, M., Faulkner, G., Fletcher, C. F., Fukushima, T., Furuno, M., Futaki, S., Gariboldi, M., Georgii-Hemming, P., Gingeras, T. R., Gojobori, T., Green, R. E., Gustincich, S., Harbers, M., Hayashi, Y., Hensch, T. K., Hirokawa, N., Hill, D., Huminiecki, L., Iacono, M., Ikeo, K., Iwama, A., Ishikawa, T., Jakt, M., Kanapin, A., Katoh, M., Kawasawa, Y., Kelso, J., Kitamura, H., Kitano, H., ...
Dufresne, Squires, Brenner, and Grier study the diffusion of two micron-sized silica spheres in their letter, Hydrodynamic Coupling of Two Brownian Spheres to a Planar Surface. The authors study the spheres diffusion coefficients and determine how the proximity to a flat surface affects diffusion. If you are interested in equations describing diffusion the wikipedia page on the Diffusion Equation is a good place to start. In the Wikimedia Commons video below, food coloring is dropped into two glasses of water. Can you figure out which glass contains hot water and which contains cold water? Click here for the answer. ...
Dufresne, Squires, Brenner, and Grier study the diffusion of two micron-sized silica spheres in their letter, Hydrodynamic Coupling of Two Brownian Spheres to a Planar Surface. The authors study the spheres diffusion coefficients and determine how the proximity to a flat surface affects diffusion. If you are interested in equations describing diffusion the wikipedia page on the Diffusion Equation is a good place to start. In the Wikimedia Commons video below, food coloring is dropped into two glasses of water. Can you figure out which glass contains hot water and which contains cold water? Click here for the answer. ...
Whats Preparing in University or college? Dont be pleasantly surprised if your eating out in undergrad takes alot more then a passing desire for what goes on in the kitchen this Thanksgiving holiday. The Celtics Globe information that the premiere course in Harvard that fall is the Science with the Physical Whole world 27, better known as Science and even Cooking: From Haute Dinning to Tender Matter Scientific research. According to the Community , The class includes drawn unrivaled interest. About 600 students were definitely selected by way of lottery through among 900 who applied, some of who wrote works and interests further all their chances of classes. Offered via Harvards The school of Technological innovation and Techniques, the class suits twice one week. On Thursdays, physics mentor David Weitz or placed math teacher Michael Brenner lectures about the scientific standards. The following Tues, a visitor parking area chef reflects how all those principles provide the foundation ...
TY - JOUR. T1 - Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4−8− αβ T cells demonstrates preferential use of several Vβ genes and an invariant TCR α chain. AU - Porcelli, Steven. AU - Yockey, Courtland E.. AU - Brenner, Michael B.. AU - Balk, Steven P.. N1 - Copyright: Copyright 2017 Elsevier B.V., All rights reserved.. PY - 1993/7/1. Y1 - 1993/7/1. N2 - CD4−CD8− (double negative [DN]) α/β T cells are a largely uncharacterized subpopulation of unknown function. To investigate whether these cells are selected to recognize particular antigens or antigen-presenting molecules, DN α/β T ceils were purified from the peripheral blood of five normal donors and their T cell receptor (TCR) α and β chains were examined. Random cloning of TCR α chains by single-sided polymerase chain reaction (PCR) amplification identified an invariant rearrangement between Vα24 and JαQ, with no N region diversity, which was expressed preferentially by DN α/β T ...
Dr. Sydney Brenner, the visionary molecular biologist and Nobel laureate who turned a humble soil worm into one of the most-studied organisms in biology, passed away on April 5, 2019 in Singapore. He was 92.. ...
Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant. Gerdemann, Ulrike; Katari, Usha L; Papadopoulou, Anastasia; Keirnan, Jacqueline M; Craddock, John A; Liu, Hao; Martinez, Caridad A; Kennedy-Nasser, Alana; Leung, Kathryn S; Gottschalk, Stephen M; Krance, Robert A; Brenner, Malcolm K; Rooney, Cliona M; Heslop, Helen E; Leen, Ann M // Molecular Therapy;Nov2013, Vol. 21 Issue 11, p2113 Adoptive transfer of virus-specific T cells can prevent and treat serious infections with Epstein-Barr virus (EBV), cytomegalovirus (CMV), and adenovirus (Adv) after allogeneic hematopoietic stem cell transplant. It has, however, proved difficult to make this approach widely available since... ...
Mallarino R, Campàs O, Fritz JA, Burns KJ, Weeks OG, Brenner MP, et al.. Closely related bird species demonstrate flexibility between beak morphology and underlying developmental programs. Proc Natl Acad Sci U S A. 2012 ;109(40):16222-7. ...
Luxembourg Institute of Health (LIH) researcher Davide Franchina, a PhD student funded by the FNRs AFR Bilateral programme, and FNR ATTRACT Fellow Dirk Brenner…
Carninci, P., Kasukawa, T., Katayama, S., Gough, J., Frith, M. C., Maeda, N., Oyama, R., Ravasi, T., Lenhard, B., Wells, C., Kodzius, R., Shimokawa, K., Bajic, V. B., Brenner, S. E., Batalov, S., Forrest, A. R. R., Zavolan, M., Davis, M. J., Wilming, L. G., Aidinis, V., Allen, J. E., Ambesi-Impiombato, A., Apweiler, R., Aturaliya, R. N., Bailey, T. L., Bansal, M., Baxter, L., Beisel, K. W., Bersano, T., Bono, H., Chalk, A. M., Chiu, K. P., Choudhary, V., Christoffels, A., Clutterbuck, D. R., Crowe, M. L., Dalla, E., Dalrymple, B. P., de Bono, B., Gatta, G. D., Bernardo, D. d., Down, T., Engstrom, P., Fagiolini, M., Faulkner, G., Fletcher, C. F., Fukushima, T., Furuno, M., Futaki, S., Gariboldi, M., Georgii-Hemming, P., Gingeras, T. R., Gojobori, T., Green, R. E., Gustincich, S., Harbers, M., Hayashi, Y., Hensch, T. K., Hirokawa, N., Hill, D., Huminiecki, L., Iacono, M., Ikeo, K., Iwama, A., Ishikawa, T., Jakt, M., Kanapin, A., Katoh, M., Kawasawa, Y., Kelso, J., Kitamura, H., Kitano, H., ...
ex binding domain for reg & tf or sox10). NMD fixes this; truncated case now looks like hemizyg.. ## Related twitter dialogue:. Brenner: expl. how premature truncation is often a dominant neg. (ex SOX10), providing a rationalization for the purpose of NMD #ISMB #LBR01. @rtraborn · Jul ...
Lou Brenner, MD, has served as chief executive officer of Allena since February 2019 and as president since February 2017. He previously served as chief operating officer from April 2015 to January 2019.. Lou has more than a decade of industry leadership experience, including pharmaceutical development strategy, regulatory affairs, business development, and commercialization. Prior to joining Allena, Lou served as chief medical officer at Idera Pharmaceuticals, chief medical officer at Radius Health, and senior vice president at AMAG Pharmaceuticals. He began his industry career at Genzyme Corporation, where he led successful product development programs for medicines that are currently marketed in the renal and metabolic areas.. He holds an MD from Duke University, an MBA from Harvard Business School, and a BS from Yale University, He completed his residency in internal medicine at Brigham and Womens Hospital and his fellowship in nephrology at Brigham and Womens Hospital and Massachusetts ...
Theres a insufficient contemporary prospective data examining the ABVD (adriamycin, bleomycin, vinblastine, dacarbazine) and Stanford V (SV; doxorubicin, vinblastine, mechlorethamine, vincristine, bleomycin, etoposide, prednisone) regimens in old Hodgkin lymphoma (HL) individuals. been retrospective analyses which were reported in the 1980sC1990s; these analyses demonstrated 5-year overall success (Operating-system) rates of around 30%C45% (Levis, 1996, Mir, 1993, Roy, 2000, Stark, 2002, Weekes, 2002) A recently available Surveillance, Epidemiology and FINAL RESULTS (SEER) Program record indicated that results for HL in old individuals had improved as time passes (Brenner, 2008). Its important to note, nevertheless, that success rates in the last era (1980C1984) had been remarkably low (~20%), as the 2000C2004 survival rates remained significantly inferior compared with that seen in younger populations. Moreover, a recent retrospective analysis of older HL patients treated in the contemporary ...
Rockets fired on southern Israel after IDF predawn strike on Nov. 12 killed Baha Abu Al-Atta, Palestinian Islamic Jihad northern command chief in the Gaza Strip. The blast ripped through his home in Gaza Citys Shejaia district. His wife was also killed and two children injured. An IDF statement said Prime Minister Minister Binyamin Netanyahu had authorized the operation against Al-Atta, accusing him of carrying out a recent series of cross-border rocket, drone and sniper attacks and planning more.. Islamic Jihad, in its own statement, confirmed Al-Attas death and threatened retaliation against Israel. Rocket alerts in Ashdod, Gedera, Lachish and towns adjoining Gaza. Schoolchildren ordered to stay home in southern Israel including Ashdod and Beersheba as well as the Tel Aviv region. Roads are blocked and the military reinforcements are streaming to the Gaza Area. First rockets have reached Gedera and Kibbutz Givat Brenner. Population as far north as Greater Tel Aviv advised to stay home in ...
TY - JOUR. T1 - Bone marrow transplantation for therapy-induced acute myeloid leukemia in children with previous lymphoid malignancies. AU - Hale, G. A.. AU - Heslop, Helen. AU - Bowman, L. C.. AU - Rochester, R. A.. AU - Pui, C. H.. AU - Brenner, Malcolm. AU - Krance, R. A.. PY - 1999. Y1 - 1999. N2 - Twenty-one children who developed therapy-related acute myeloid leukemia after treatment for acute lymphoblastic leukemia received allogeneic bone marrow transplants between January 1990 and June 1997. All had previously received epipodophyllotoxin-containing regimens and 11 had cytogenetic abnormalities involving 11q23. Induction chemotherapy was given to 13 patients and eight patients went directly to BMT. Eleven received marrow from matched siblings, eight from matched unrelated donors and two from haploidentical family members. Conditioning regimens included cyclophosphamide (CY), cytarabine, and total body irradiation. Four patients are alive disease-free between 1118 and 1825 days post-BMT ...
The Brenner research lab has four key research interests involving computational and experimental genomics.. Gene regulation by alternative splicing and nonsense-mediated mRNA decay. Nonsense-mediated mRNA decay (NMD) is a cellular RNA surveillance system that recognizes transcripts with premature termination codons and degrades them. Several years ago, we discovered large numbers of natural alternative splice forms that appear to be targets for NMD, and we speculated that this might be a mode of gene regulation which we termed rust (regulated unproductive splicing and translation). This seems to be confirmed by our finding that all conserved members of the SR family of splice regulators have an unproductive alternative mRNA isoform targeted for NMD1. Strikingly, the splice pattern for each is conserved in mouse and always associated with an ultraconserved or highly-conserved region of ~100 or more nucleotides of perfect identity between human and mouse. Remarkably, this seems to have evolved ...
Read or download book entitled Chronic Kidney Disease Dialysis and Transplantation written by T. Alp Ikizler which was release on 01 October 2018, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: From basic science to practical clinical tools, Chronic Kidney Disease, Dialysis, and Transplantation, 4th Edition provides you with the up-to-date, authoritative guidance you need to safely and effectively manage patients with chronic renal disease. Covering all relevant clinical management issues, this companion volume to Brenner and Rectors The Kidney presents the knowledge and expertise of renowned researchers and clinicians in the fields of hemodialysis, peritoneal dialysis, critical care nephrology, and transplantation - for an all-in-one, indispensable guide to every aspect of this fast-changing field. Contains expanded content on economics and outcomes of treatment, as well as acute kidney injury. Covers hot topics such as the genetic causes of chronic ...
During thymocyte development, progression from T cell receptor (TCR) to TCR rearrangement is normally mediated with a CD3-linked pre-TCR made up of the TCR string paired with pre-TCR (pT). routine, downregulate surface pre-TCR rapidly, and be little relaxing pre-T cells finally, prior to the onset of TCR gene appearance. A.S., Oslo, Norway) combined to the next mAbs: anti-TCR/ (BMA031 [guide 22]; supplied by Dr. R. Kurrle, Behringwerke AG, Marburg, Germany); anti-TCR/ (TCR1 [guide 23]; supplied by Dr. M. Brenner, Brigham and Womens Medical center, Boston, MA); anti-CD19 (A.S.), anti-CD56 (Leu-19; A.S.), and Compact disc4+Compact disc8?CD3? thymocytes had been then sorted from your CD8-depleted pool with anti-CD4Ccoated beads (A.S.), as explained (15). Cells in the former subset (referred to as large TCR/? DP thymocytes) were either CD3? or CD3low. Isolation of the CD3? cells (referred to as large CD3? DP thymocytes) was performed by depletion of CD3low cells with anti-CD3Ccoated magnetic beads ...

No data available that match "brenner tumor"


The term "Brenner tumor" was first used by Robert Meyer, in 1932. Micrograph of a Walthard cell nest, the entity Brenner ... Brenner tumors are an uncommon subtype of the surface epithelial-stromal tumor group of ovarian neoplasms. The majority are ... The same crystals were also noted under high power view in Brenner tumors.[1] It is named for Fritz Brenner (1877-1969), a ... without the characteristic stromal/epithelial pattern of a Brenner tumour. Histologically, Leydig cell tumors of the testes and ...
Case report of a malignant Brenner tumor with hyperestrogenism * * JOH Kensuke * Departments of Pathology The Jikei University ... Malignant Brenner tumor of the ovary. Electron microscopic study of a case responsive to radiation and chemotherapy HAID M. ... Malignancy in Brenner tumors of the ovary, with comments on histogenesis and possible estrogen production IDELSON MG. ... Brenner tumor of the ovary with Leydig cell hyperplasia. A histologic and ultrastructural study HAMEED K. ...
The origin of Brenner tumors is perplexing, but they are believed to arise from transitional cell metaplasia occurring within ... The origin of Brenner tumors is perplexing, but they are believed to arise from transitional cell metaplasia occurring within ... The origin of Brenner tumors is perplexing, but they are believed to arise from transitional cell metaplasia occurring within ... The origin of Brenner tumors is perplexing, but they are believed to arise from transitional cell metaplasia occurring within ...
Brenner tumour explanation free. What is Brenner tumour? Meaning of Brenner tumour medical term. What does Brenner tumour mean? ... Looking for online definition of Brenner tumour in the Medical Dictionary? ... Brenner tumour. Also found in: Wikipedia. Brenner tumour. A tumour that constitutes , 2% of ovarian tumours, which presents at ... BRENNER TUMOUR (FIGURE 3): Among the remaining epithelial tumours, 1(2%) case of malignant Brenner tumour was found in our ...
Brenner tumor of ovary; Brenner tumor of the ovary; Transitional cell tumour of the ovary; Ovarian transitional cell tumour ... Brenner tumor is a uncommon benign subtype of the surface epithelial-stromal tumor of the ovary. Brenner tumor was first ... Brenner tumor is more commonly observed among post-menopausal women.. Race. *There is no racial predilection for Brenner tumor. ... The majority of Brenner tumors are unilateral.. *Genes involved in the pathogenesis of Brenner tumor, include EGFR, RAS, Cyclin ...
He described what was later called Brenner Tumor.. These tumors are rare epithelial ovarian tumors that account for 1-2% of ... Tumors of borderline malignancy are less frequent and only about 1% of Brenner tumors are malignant. ... Brenner Tumor. Written by Ivo Mitsiev at 02/24/2012, 11:32pm. in "General Surgery".. ... In 1907 Fritz Brenner published his thesis Das Oophoroma folliculare.. F. Brenner: Das Oophoroma folliculare. Frankfurter ...
The Brenner tumour, abbreviated BT, is an ovarian tumour in the epithelial group of ovarian tumours. ... Gezginç, K.; Karatayli, R.; Yazici, F.; Acar, A.; Çelik, Ç.; Çapar, M.; Tavli, L. (Aug 2012). "Malignant Brenner tumor of the ... Dec 2013). "Ovarian Brenner tumour: a morphologic and immunohistochemical analysis suggesting an origin from fallopian tube ... "Brenner tumor of ovary: An incidental finding.". J Midlife Health 2 (1): 40-1. doi:10.4103/0976-7800.83273. PMC 3156501. PMID ...
... Posted by Rathachai Kaewlai, M.D. Ultrasound image of the right ovary shows a well-circumscribed ... Brenner tumors of the ovary sonographic and computed tomographic imaging features. J Ultrasound Med 2006;25:1245-1251. ... Potential tumors: serous and mucinous cystadenoma/cystadenocarcinoma, teratoma, clear cell carcinoma, endometrioid carcinoma, ... Long list of potential causes, encompassing tumor (primary and neoplastic), inflammation and infection in a postmenopausal ...
Brenner Tumor. Diagnostic in Sion, Switzerland ✈ Find the best medical programs at BookingHealth - ✔Compare the prices ✔Online ... Brenner Tumor Diagnostics #214245. Gynecological diseases are the diseases of female genital organs. Our Female Clinic is ... Gynecology: Brenner Tumor. Diagnostic in Switzerland, Sion See also for brenner tumor:. *Surgery ...
Brenner Tumor ✈ Find the leading clinics and hospitals for Diagnostic at BookingHealth - ✔Get fast quotes ✔Compare the prices ✔ ... Brenner Tumor Diagnostics #361777. Department of Mammology, Gynecology and Obstetrics offers a full range of services in these ... Brenner Tumor Diagnostics #356807. The Department of Gynecology and Gynecologic Oncology offers the full range of services in ... Brenner Tumor Diagnostics #330309. The Department of Obstetrics and Gynecology of Lis Maternity Hospital at the Tel Aviv ...
... stromal tumors explanation free. What is stromal tumors? Meaning of stromal tumors medical term. What does stromal tumors mean? ... Looking for online definition of stromal tumors in the Medical Dictionary? ... Brenner tumor. See: Brenner tumor. brown tumor. A benign fibrotic mass found within the bone of patients with unchecked ... Steroid cell tumor, Sugar tumor, Theca cell tumor, Triton tumor, Turban tumor, Warthins tumor, Wilms tumor, Yolk sac tumor. ...
BRENNER TUMORS AND ESTROGEN PRODUCTION. FARRAR, H. K. JR.; ELESH, RICHARD; LIBRETTI, JOSEPH ...
Introduction: Brenner tumor of the ovary represents an uncommon neoplasm. It constitutes about 1.5% of all ovarian tumors with ... N2 - Introduction: Brenner tumor of the ovary represents an uncommon neoplasm. It constitutes about 1.5% of all ovarian tumors ... AB - Introduction: Brenner tumor of the ovary represents an uncommon neoplasm. It constitutes about 1.5% of all ovarian tumors ... Brenner tumor of the ovary represents an uncommon neoplasm. It constitutes about 1.5{\%} of all ovarian tumors with a peak of ...
... Surface epithelial-stromal tumorClassification & external resources ICD-10 C56., D27. ICD-9 ... Brenner tumor. Brenner tumors are uncommon surface-epithelial stromal cell tumors in which the epithelial cell (which defines ... Brenner tumors may be benign or malignant, depending on whether or not the tumor cells invade the surrounding tissue. ... a well-differentiated tumor closely resembles benign tumors *a poorly differentiated tumor may not resemble the cell type of ...
... disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Brenner tumor ... Brenner tumor. of the ovary is a solid, abnormal growth (tumor) on the ovary. Most Brenner tumors are not cancerous (benign). ... Treatment of Brenner tumors. of the ovary usually consists of surgery to remove the tumor.[2][3][4][5] If the tumor is found to ... 1][2][3][4] Brenner tumors are ultimately diagnosed by a surgical biopsy. . Brenner tumors have specific microscopic findings ...
Brenner tumors are rare ovarian tumors, which are a subgroup of transitional cell tumors of ovary. Most of these tumors are ... Surgical removal is usually curative for benign tumors. We present a rare case of bilateral Brenner tumor of ovary with ... Specific diagnosis of Brenner tumor is difficult using imaging studies and can be definitely diagnosed only on pathological ... Bilateral Brenner tumor of ovary with associated unilateral mucinous cystadenoma: a case r ...
Clinicopathological features of ovarian Brenner tumors in Montenegro Filip Vukmirovic, Irena Vukmirovic, Mihailo Vukmirovic ... Brenner, M. Bernhard, J. Knapp, M. Sikinger, E. Martin, M. Helm, E. Popp January 23, 2013 Page range: 166-171 ... Correct recognition of FLH is extremely important, because a complete resection of the tumor can confer an excellent prognosis ...
Meigs Syndrome With an Elevated CA 125 From Benign Brenner Tumors. Buttin, Barbara M.; Cohn, David E.; Herzog, Thomas J. ... Immunohistochemical evaluation of tumor specimens after single gene sequencing for patients with endometrial cancer is a cost- ... mismatch repair in endometrial cancer are correlated with negative prognostic factors and poor outcomes compared with tumors ...
... disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Brenner tumor ... Brenner tumor of the vagina Title Other Names:. Extraovarian Brenner tumor of the vagina ...
It is in the transitional cell category of ovarian tumours which also includes malignant Brenner tumour and benign Brenner ... Brenner tumour Tazi, EM.; Lalya, I.; Tazi, MF.; Ahellal, Y.; Mrabti, H.; Errihani, H. (2010). "Transitional cell carcinoma of ... tumour. Low mag. Very high mag. The main treatment is surgical resection. These tumours do better than other types of ...
... stromal invasion must be observed for diagnosis of Brenner tumour. A case of malignant Brenner tumour is described along with a ... Full text: Available Index: IMSEAR (South-East Asia) Main subject: Ovarian Neoplasms / Ovary / Struma Ovarii / Brenner Tumor / ... Full text: Available Index: IMSEAR (South-East Asia) Main subject: Ovarian Neoplasms / Ovary / Struma Ovarii / Brenner Tumor / ... Brenner Tumor/pathology , Female , Humans , Middle Aged , Ovarian Neoplasms/pathology , Ovary/pathology , Struma Ovarii/ ...
Malignant Brenner tumor mimicking a primary squamous cell carcinoma of the cervix. / Badve, Sunil; Fehmian, C.; Cass, I.; ... Malignant Brenner tumor mimicking a primary squamous cell carcinoma of the cervix. Gynecologic Oncology. 1999 Sep;74(3):487-490 ... Badve, S., Fehmian, C., Cass, I., Goldberg, G. L., & Jones, J. G. (1999). Malignant Brenner tumor mimicking a primary squamous ... Badve, Sunil ; Fehmian, C. ; Cass, I. ; Goldberg, G. L. ; Jones, J. G. / Malignant Brenner tumor mimicking a primary squamous ...
Mixed Tumor, Mullerian. Brenner Tumor. Neoplasms by Histologic Type. Neoplasms. Endocrine Gland Neoplasms. Neoplasms by Site. ... Malignant Mixed Mullerian Tumor Ovarian Carcinosarcoma Adenocarcinoma of the Appendix Brenner Tumor of Ovary Ovarian Cancer ... Brenner Tumor Fallopian Tube Cancer Ovarian Carcinosarcoma Ovarian Clear Cell Cystadenocarcinoma Ovarian Endometrioid ... No history or evidence (upon physical examination) of CNS disease, including primary brain tumor, seizures not controlled with ...
Fallopian Tube Carcinoma Malignant Ovarian Mixed Epithelial Tumor Ovarian Brenner Tumor Ovarian Clear Cell Cystadenocarcinoma ... Brenner Tumor. Neoplasms by Histologic Type. Neoplasms. Endocrine Gland Neoplasms. Neoplasms by Site. Ovarian Diseases. Adnexal ... Complete and Partial Tumor Response by Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.0). Per RECIST v1.0 for ... A6 may stop the growth of tumor cells by blocking blood flow to the tumor. ...
Brenner tumor].. Kozachenko VP, Adamian RT, Pichugina MN, Filatova AM.. Akush Ginekol (Mosk). 1981 Sep;(9):12-4. Russian. No ... Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation. ...
tumor answers are found in the Tabers Medical Dictionary powered by Unbound Medicine. Available for iPhone, iPad, Android, and ... SEE: Brenner tumor. brown tumor. A benign fibrotic tumor found within the bone of patients with unchecked hyperparathyroidism. ... uterine tumor. tumor of the uterus A uterine neoplasia, which may cause sterility or abortion or obstruct labor. Such tumors ... secondary tumor. A tumor that has formed at a location remote from the original location of the tumor. Generally, a secondary ...
Clinicopathological features of ovarian Brenner tumors].. Zhong PP, Zhu L, Zhang LH, Zheng XZ, Chen TB, Xu F, Zhan Y, Yin CH, ...
Brenner tumor cells also expressed uroplakins Ia and II. CA125 was observed focally in some Brenner tumors. In contrast, TCCs ... To determine whether Brenner tumors and transitional cell carcinomas (TCCs) of the ovary are urothelial in type, the ... Brenner tumors but not transitional cell carcinomas of the ovary show urothelial differentiation: immunohistochemical staining ... Thus, it appears that the only true urothelial-type ovarian neoplasm is the Brenner tumor, whereas ovarian TCC most likely ...
Tumour markers in mucinoid tumours May have raised CEA and CA19-9. May have normal CA125 ...
What epithelial ovarian tumour class is this: no cytological abnormalities, proliferative activity absent, no stromal invasion ... What epithelial ovarian tumour class is this: cytological abnomralities, proliferative, no stromal invation ... most common malignant primitive germ cell tumour. 1-2% of all malignant ovarian tumours. Almost exclusively children and young ... A type of ovarian sex cord/stromal tumour which is benign, may produce oestrogen causing uterine bleeding? ...
  • Transitional cell carcinoma is an even rarer entity, in which neoplastic transitional epithelial cells similar to transitional cell carcinoma of the bladder are seen in the ovary, without the characteristic stromal/epithelial pattern of a Brenner tumour. (wikipedia.org)
  • Cytology of ascitic fluid in a patient with metastasizing malignant Brenner tumor of the ovary. (wikipedia.org)
  • Malignant Brenner tumor of the ovary. (nii.ac.jp)
  • Brenner tumor of the ovary with Leydig cell hyperplasia. (nii.ac.jp)
  • The origin of Brenner tumors is perplexing, but they are believed to arise from transitional cell metaplasia occurring within the ovary and/or fallopian tube, although it is controversial whether this metaplasia is truly along transitional cell lines. (elsevier.com)
  • To explore this further, we investigated a series of 19 Brenner tumors of the ovary (15 benign and 4 malignant) for the presence of TERT promoter mutations after genomic DNA extraction from formalin-fixed paraffin-embedded tissue blocks and standard polymerase chain reaction sequencing. (elsevier.com)
  • The findings also may portend diagnostic utility in rare cases wherein it is difficult to distinguish a primary malignant Brenner tumor of the ovary from metastatic UC. (elsevier.com)
  • TCC of the ovary is defined as ovarian tumours presenting with histologic features similar to those seen in a malignant Brenner tumour , but lacking the associated benign Brenner tumour component. (thefreedictionary.com)
  • Malignant brenner tumour and transitional cell carcinoma of the ovary: a comparison. (thefreedictionary.com)
  • Brenner tumor is a uncommon benign subtype of the surface epithelial-stromal tumor of the ovary. (wikidoc.org)
  • The tumor had its origin from the left ovary pushing the sigmoid colon to the right side having embedded the left ureter. (forsurgeons.net)
  • TCC of the ovary is probably distinct from the malignant Brenner tumour. (librepathology.org)
  • Transitional cell carcinoma of the ovary is related to high-grade serous carcinoma and is distinct from malignant brenner tumor. (librepathology.org)
  • Malignant Brenner tumor of the ovary: analysis of 13 cases. (librepathology.org)
  • Brenner tumor of ovary: An incidental finding. (librepathology.org)
  • Introduction: Brenner tumor of the ovary represents an uncommon neoplasm. (elsevier.com)
  • Materials and methods: Here we present the case of a patient affected by a malignant Brenner tumor of the ovary, with metastases to brain, lung and liver and by a concomitant low grade endometroid adenocarcinoma of the uterus. (elsevier.com)
  • The malignant form of this tumor, serous cystadenocarcinoma, accounts for approximately 40% of all carcinomas of the ovary and are the most common malignant ovarian tumors. (bionity.com)
  • Brenner tumor of the ovary is a solid, abnormal growth (tumor) on the ovary. (cdc.gov)
  • Approximately 90% of Brenner tumors of the ovary are first discovered by chance during surgery, a routine pelvic exam or an ultrasound . (cdc.gov)
  • Treatment of Brenner tumors of the ovary usually consists of surgery to remove the tumor. (cdc.gov)
  • The long-term outlook for individuals with cancerous or borderline Brenner tumors depends on the stage of the cancer when it is diagnosed and if the cancer has spread beyond the ovary. (cdc.gov)
  • ClinicalTrials.gov lists trials that are related to Brenner tumor of ovary. (cdc.gov)
  • Brenner tumors are rare ovarian tumors , which are a subgroup of transitional cell tumors of ovary . (bvsalud.org)
  • These tumors are mostly small, solid and asymptomatic, seen commonly in association with mucinous cystadenomas of ovary . (bvsalud.org)
  • To determine whether Brenner tumors and transitional cell carcinomas (TCCs) of the ovary are urothelial in type, the immunoprofiles of 14 Brenner tumors, including three malignant examples, and eight ovarian TCCs were compared with those of Walthard nests, urothelium, 12 urinary bladder TCCs and 17 ovarian adenocarcinomas (serous, endometrioid, mucinous, and undifferentiated type). (qxmd.com)
  • CK7 and CK8 were broadly expressed in most tumors of ovary and bladder examined, while vimentin was focally present in some ovarian TCCs and adenocarcinomas. (qxmd.com)
  • Reported rates of mucinous carcinoma diagnoses have declined dramatically, but expert pathology reviews suggest that this reflects increased recognition of metastases from occult gastrointestinal primary tumors to the ovary, rather than a true decline in rates of ovarian primary tumors. (cigna.com)
  • You find a tumor that is in the ovary and is composed of hair, sebum, and some poorly formed teeth. (studystack.com)
  • Alpha-fetoprotein (AFP) is a glycoprotein that is produced in early fetal life by the liver and by a variety of tumors including hepatocellular carcinoma, hepatoblastoma, and nonseminomatous germ cell tumors of the ovary and testis. (jhu.edu)
  • Germ cell tumors represent 15% to 20% of all tumors of the ovary. (medscape.com)
  • Although these account for only 4% of all ovarian tumors, they are the most common solid primary tumor of the ovary. (medscape.com)
  • Lastly, transitional cell tumors of the ovary, specifically malignant Brenner tumors, are quite uncommon. (cancernetwork.com)
  • Bilateral Signet-ring Stromal Tumor of the Ovary: A Case Report With Next-generation Sequencing Analysis and FOXL2 Mutation Testing. (amedeo.com)
  • Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study. (termedia.pl)
  • These tumors generally behave in an indolent fashion, are confined to the ovary at presentation and, as a group, are relatively genetically stable. (nih.gov)
  • Recent studies have also provided cogent evidence that what have been traditionally thought to be primary ovarian tumors actually originate in other pelvic organs and involve the ovary secondarily. (nih.gov)
  • A solid or cystic tumor composed of crowded glands lined by atypical endometrioid-type cells and lacking destructive stromal invasion and/or confluent glandular growth. (jhu.edu)
  • BOTs have been identified in all epithelial subtypes, including endometrioid, clear cell and Brenner (transitional cell), but serous (53.3%) and mucinous histologies (42.5%) are most common. (laparoscopyhospital.com)
  • One group of tumors, designated type I, is composed of low-grade serous, low-grade endometrioid, clear cell, mucinous and transitional (Brenner) carcinomas. (nih.gov)
  • Endometrioid and clear cell tumors have been associated with endometriosis that is regarded as the precursor of these tumors. (nih.gov)
  • The purpose of this study is to determine the safety and tolerability of OXi4503 in subjects with relapsed or refractory carcinomas with hepatic tumor burden. (bioportfolio.com)
  • Results: 30.2% and 8.3% of serous and mucinous carcinomas respectively were ER positive while 41.2% and 22.5% of both tumour types were PR positive. (bireme.br)
  • Ovarian cancer is a rare disease, with carcinomas comprising approximately 90% of tumors and germ cell and stromal tumors accounting for the remainder. (cigna.com)
  • The category of ovarian borderline tumor or tumor of low-malignant potential, which historically had been considered in the context of ovarian cancer, is now generally considered a nonmalignant entity, although it has a postulated relationship with the development of some histologic subtypes of low-grade ovarian carcinomas. (cigna.com)
  • It is now well-accepted that high-grade and low-grade serous carcinomas represent distinct entities rather than a spectrum of the same tumor type. (cancernetwork.com)
  • Mucinous carcinomas typically present as large unilateral masses and often show areas of mucinous cystadenoma and mucinous borderline tumor. (cancernetwork.com)
  • It must be emphasized that primary mucinous carcinomas are uncommon tumors, and metastasis from other sites such as the appendix, colon, stomach, and pancreaticobiliary tract must always be considered in the differential diagnosis. (cancernetwork.com)
  • and only one malignant Brenner tumor (0.5%) and no pure transitional cell carcinomas were identified. (nih.gov)
  • Moreover, the carcinomas exhibit a shared lineage with the corresponding benign cystic neoplasm, often through an intermediate (borderline tumor) step, supporting the morphologic continuum of tumor progression. (nih.gov)
  • Brenner tumors are an uncommon subtype of the surface epithelial-stromal tumor group of ovarian neoplasms. (wikipedia.org)
  • Brenner tumors are uncommon ovarian neoplasms, which have morphologic and immunophenotypical features of transitional cell (urothelial) differentiation. (elsevier.com)
  • Molecular evidence supporting that Brenner tumors represent neoplasms exhibiting transitional cell differentiation is scant. (elsevier.com)
  • Brenner tumours account for approximately 3.2% of ovarian epithelial neoplasms. (wikidoc.org)
  • These tumors are rare epithelial ovarian tumors that account for 1-2% of all ovarian neoplasms. (forsurgeons.net)
  • Tumors are also called neoplasms , which means that they are composed of new and actively growing tissue. (thefreedictionary.com)
  • Surface epithelial-stromal tumors are a class of ovarian neoplasms that may be benign or malignant . (bionity.com)
  • A smooth, solid or cystic fibroepithelial (FIBROEPITHELIAL NEOPLASMS) tumor, usually found in the OVARIES but can also be found in the adnexal region and the KIDNEYS. (bioportfolio.com)
  • In order to explore the histogenesis of these neoplasms, we undertook a clonality analysis of the two components of ten combined Brenner and mucinous tumours using a human androgen receptor gene (HUMARA) assay. (elsevier.com)
  • A neoplasm of transitional cell type (resembling non-invasive, low-grade, urothelial neoplasms) displaying epithelial proliferation beyond that seen in benign Brenner tumors and lacking stromal invasion. (jhu.edu)
  • Ovarian surface epithelial neoplasms composed of transitional (urothelial)-type epithelial cells (benign, low malignant potential (borderline), or malignant (malignant Brenner, transitional cell carcinoma)) comprise approximately 2% of all primary surface epithelial neoplasms. (uottawa.ca)
  • Researchers analyzed the sensitivity and accuracy of two fecal occult blood tests in detecting advanced colorectal neoplasms, tumors that can either be malignant or benign. (bio-medicine.org)
  • Other less common ovarian cancers included papillary cyst adenocarcinoma (3 cases), clear cell carcinoma (2 cases) and malignant Brenner tumour (2 cases). (thefreedictionary.com)
  • Undifferentiated carcinoma - no Brenner tumour component. (librepathology.org)
  • I. To assess the activity of A6, as measured by the 6-month progression-free survival (PFS) rate and objective tumor response (complete or partial) rate, in patients with persistent or recurrent ovarian epithelial, fallopian tube, or primary peritoneal carcinoma. (clinicaltrials.gov)
  • Urothelial carcinoma (UC) invasive into the muscularis propria or tumors unresponsive to treatment are indications for cystectomy. (bireme.br)
  • 10 ] Further, among carriers of deleterious mutations in BRCA1 or BRCA2, increasing evidence suggests that many tumors previously classified as ovarian high-grade serous carcinoma may develop from malignant cells arising in tubal epithelium (serous tubal intraepithelial carcinoma [STIC]), although these tumors continue to be referred to as ovarian cancers in most writings. (cigna.com)
  • Non-invasive tumors that display greater epithelial proliferation and cytological atypia than benign serous tumors but less than low-grade serous carcinoma (LGSC). (jhu.edu)
  • Less common are transitional cell tumors, including transitional cell carcinoma and malignant Brenner tumor. (cancernetwork.com)
  • However, molecular testing of these tumors, unlike in endometrial carcinoma, is not routinely used in clinical practice. (cancernetwork.com)
  • Using the procarcinogen diethylnitrosamine (DEN) to initiate tumorigenesis in mice, we discovered that TCS substantially accelerates hepatocellular carcinoma (HCC) development, acting as a liver tumor promoter. (pnas.org)
  • These tumors include enteric-type adenoma, squamous cell- and other types of carcinoma, malignant mixed müllerian tumor, and both benign and malignant mixed tumor of the vagina (3, 12, 14, 15). (prolekare.cz)
  • Peritoneal Carcinomatosis From Yolk Sac Tumor in a Postmenopausal Woman Following Chemotherapy for High-grade Ovarian Serous Carcinoma. (amedeo.com)
  • Particularly, serous tubal intraepithelial carcinoma (STIC), a noninvasive tumor lesion formed preferentially in the distal fallopian tube epithelium, was proposed as a precursor for HGSC. (mdpi.com)
  • Here we present a rare case of struma ovarii with papillary thyroid carcinoma, and we review the management and treatment option of this rare tumour. (hindawi.com)
  • Transitional cell carcinoma of the endometrium associated with a benign ovarian Brenner tumor: a case report. (termedia.pl)
  • Kalemkerian GP, Darwish B, Varterasian ML. Tumor lysis syndrome in small cell carcinoma and other solid tumors. (medscape.com)
  • Acute tumor lysis syndrome after thalidomide therapy in advanced hepatocellular carcinoma. (medscape.com)
  • Type II tumors include conventional high-grade serous carcinoma, undifferentiated carcinoma, and malignant mixed mesodermal tumors (carcinosarcoma). (nih.gov)
  • The purpose of this study is to establish the Maximum Tolerated Dose (MTD) of OXi4503 given by weekly infusions to patients with advanced solid tumors. (bioportfolio.com)
  • The purpose of this study, the first clinical trial of JI-101, is to determine the maximum tolerated dose of JI-101 when given orally to patients with solid tumors. (bioportfolio.com)
  • This aim of study to assess the safety and tolerability of SHR7390 and to define the maximum tolerated dose (MTD) of SHR7390 in the patients with advanced solid tumors. (bioportfolio.com)
  • Prognostic value of DcR3 in solid tumors: A meta-analysis. (bioportfolio.com)
  • Decoy receptor 3 (DcR3) has been reported to be overexpressed in a wide range of solid tumors, suggesting that DcR3 plays a crucial role in the development and progression of cancer. (bioportfolio.com)
  • Dendritic Cell-Based Immunotherapy for Solid Tumors. (bioportfolio.com)
  • As a treatment for solid tumors, dendritic cell (DC)-based immunotherapy has not been as effective as expected. (bioportfolio.com)
  • The clinicopathological and prognostic value of long non-coding RNA ZEB1-AS1 in solid tumors: A meta-analysis. (bioportfolio.com)
  • However, in clinical studies and in mouse models, some solid tumors are found with no lymphocytes. (bioportfolio.com)
  • Radioimmunotherapy of solid tumors: Approaches on the verge of clinical application. (bioportfolio.com)
  • While radioimmunotherapy (RIT) for the treatment of hematological malignancies such as indolent B-cell lymphoma has proven quite successful, clinical results of RIT in solid tumors have only been mode. (bioportfolio.com)
  • An alkylating agent of value against both hematologic malignancies and solid tumors. (bioportfolio.com)
  • This study will determine the safety and maximum tolerated dose of ONO-7579 in patients with advanced solid tumors, and evaluate efficacy of ONO-7579 in patients with advanced solid tumors. (bioportfolio.com)
  • A Phase 1b/2 Study of the Bruton Tyrosine Kinase Inhibitor Ibrutinib and the PD-L1 Inhibitor Durvalumab in Patients with Pretreated Solid Tumors. (bioportfolio.com)
  • NY-ESO-1 expression in solid tumors predicts prognosis: A systematic review and meta-analysis. (bioportfolio.com)
  • Interventional Radiology-Guided Procedures in the Treatment of Pediatric Solid Tumors: A Systematic Review and Meta-Analysis from the Group of Young Pediatric Surgeons of Europe. (bioportfolio.com)
  • The use of interventional radiology (IR) in the treatment of pediatric solid tumors has markedly increased over the last three decades. (bioportfolio.com)
  • Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors. (bioportfolio.com)
  • We investigated the role of chemokines in regulating T cell accumulation in solid tumors. (bioportfolio.com)
  • CCL5 and CXCL9 overexpression was associated with CD8 T cell infiltration in solid tumors. (bioportfolio.com)
  • On ultrasound, these lesions are occasionally misinterpreted as solid tumors, mature cystic teratomas, or complex cysts. (appliedradiology.com)
  • However, the application of CAR T-cell therapy for solid tumors has not reached its full potential because of the lack of specific tumor antigens and inhibitory factors in suppressive tumor microenvironment (TME) (e.g., programmed death ligand-1, myeloid-derived suppressor cells, and transforming growth factor-β). (frontiersin.org)
  • There have been an increasing number of CAR T-cell clinical trials for solid tumors because of their unprecedented efficacy for non-solid tumors, particularly anti-CD19 CAR T-cell (Table 1 ). (frontiersin.org)
  • However, in solid tumors, it is particularly difficult for CAR T-cells to migrate into tumor sites because of several obstacle layers, such as the extracellular matrix, and the lack of chemokines, which are frequently mismatched with receptors in solid tumors ( 10 ). (frontiersin.org)
  • Benign solid tumors (Brenner, fibroma, thecoma , fibrothecoma) are all solid ovarian tumors that should be considered malignant with the exception of a few tumors like Brenner, fibroma, thecoma , and fibrothecoma. (thefreedictionary.com)
  • This group of tumors accounts for the majority of all ovarian tumors. (bionity.com)
  • This group of tumors accounts for 90% to 95% of all cases of ovarian cancer . (wikidoc.org)
  • Epithelial ovarian cancer comprises a heterogeneous group of tumors. (cancernetwork.com)
  • Studies have shown that epithelial ovarian cancer is not a single disease but is composed of a diverse group of tumors that can be classified based on distinctive morphologic and molecular genetic features. (nih.gov)
  • In contrast, another group of tumors, designated type II, is highly aggressive, evolves rapidly and almost always presents in advanced stage. (nih.gov)
  • It has been recently proposed that the non-germ cell group may be derived from Brenner tumours, as the association of a mucinous tumour with a Brenner tumour is frequently observed. (elsevier.com)
  • Dermoids account for 95% of all ovarian germ cell tumors. (medscape.com)
  • Malignancy in struma ovarii is a rare form of ovarian germ cell tumour. (hindawi.com)
  • Dermoid tumors are mature ovarian teratomas, slow-growing germ cell tumors that are almost always benign. (appliedradiology.com)
  • Tumors composed of mild to moderately atypical gastrointestinal-type, mucincontaining epithelial cells that show proliferation greater than that seen in benign mucinous tumors. (jhu.edu)
  • Benign mucinous tumors are characterized by a lining of tall columnar epithelial cells with apical mucin and the absence of cilia. (wikidoc.org)
  • In one study the differential diagnosis of a calcified adnexal mass usually include a degenerative uterine or intra-ligamentous myoma of an ovarian tumour such as fibrothecoma, Brenner tumour and mature or immature teratoma [6]. (thefreedictionary.com)
  • The diagnosis is made by microscopic examination of a piece of tumor obtained by a surgical biopsy . (cdc.gov)
  • Brenner tumors have specific microscopic findings that help guide diagnosis. (cdc.gov)
  • Specific diagnosis of Brenner tumor is difficult using imaging studies and can be definitely diagnosed only on pathological examination. (bvsalud.org)
  • Apart from identification of typical benign, metaplastic and/or proliferating components, stromal invasion must be observed for diagnosis of Brenner tumour. (bvsalud.org)
  • A case of malignant Brenner tumour is described along with a brief review of strict criteria of diagnosis and its biological behaviour. (bvsalud.org)
  • Offers a complete visual guide to each tumor or tumor-like lesion to assist you in the recognition and diagnosis of any tissue sample under the microscope with over 2500 high-quality, full-color illustrations. (elsevier.com)
  • MRI diagnosis of brown tumor based on magnetic susceptibility. (moffitt.org)
  • 7,8] This may be due to more accurate pathological diagnosis, protective effect of oral contraceptive pills for malignant ovarian tumors only and contributory effect of fertility drugs on BOTs. (laparoscopyhospital.com)
  • Because of its rarity, the diagnosis and management of the tumour have not been clearly defined. (hindawi.com)
  • Definitive diagnosis of ovarian tumors requires surgery to obtain the ovarian tissue for the pathologist . (jhu.edu)
  • Tumors of borderline malignancy are less frequent and only about 1% of Brenner tumors are malignant. (forsurgeons.net)
  • The pathologist could not exclude malignancy of the Brenner tumor. (forsurgeons.net)
  • Microscopic pathological features determine whether a surface epithelial-stromal tumor is benign , borderline, or malignant (evidence of malignancy and stromal invasion). (bionity.com)
  • The chance of malignancy of the tumor increases with the amount of solid areas present, including both papillary structures and any necrotic tissue present. (bionity.com)
  • Histology showed a malignant Brenner tumor with abundant squamous differentiation eroding the cervix and simulating a primary cervical malignancy. (elsevier.com)
  • Brenner tumours very rarely can occur in other locations, including the testes. (wikipedia.org)
  • Borderline and malignant Brenner tumours are possible but each are rare. (wikipedia.org)
  • Micrograph of a Walthard cell nest, the entity Brenner tumours are thought to arise from. (wikipedia.org)
  • 7] Common combinations with ovarian tumours include mucinous cystadenoma and a combination of Brenner tumour , mature cystic teratoma, Sertoli-Leidig cell tumour may be seen. (thefreedictionary.com)
  • BRENNER TUMOUR (FIGURE 3): Among the remaining epithelial tumours, 1(2%) case of malignant Brenner tumour was found in our study. (thefreedictionary.com)
  • The Brenner tumour , abbreviated BT , is an ovarian tumour in the epithelial group of ovarian tumours. (librepathology.org)
  • Mostly benign clinical course - 99% of Brenner tumours benign. (librepathology.org)
  • May be malignant - rarely (~1% of Brenner tumours [7] ). (librepathology.org)
  • It is in the transitional cell category of ovarian tumours which also includes malignant Brenner tumour and benign Brenner tumour. (wikipedia.org)
  • In addition, paired box protein 8, a highly sensitive Müllerian epithelial marker, was not detected by immunohistochemistry in either tumour component in any of the ten tumours, suggesting that this subset of mucinous tumours does not originate from Müllerian-derived epithelium. (elsevier.com)
  • In conclusion, this study demonstrates that in combined mucinous and Brenner tumours, there is a shared clonal relationship between the two different tumour components and suggests that some pure mucinous tumours may develop from a Brenner tumour in which the Brenner tumour component becomes compressed and obliterated by an expanding mucinous neoplasm. (elsevier.com)
  • Most transitional cell tumours occurring within the ovaries are benign (Brenner tumours), and are typically incidental findings discovered at laparotomy for unrelated pelvic conditions in patients during the fourth to eighth decades (mean age 50 years). (uottawa.ca)
  • Benign Brenner tumours are composed of well-demarcated nests of cytologically bland transitional-type epithelium enmeshed in prominent fibromatous stroma. (uottawa.ca)
  • Mitotic figures are rare to absent in benign Brenner tumours. (uottawa.ca)
  • Recent data show that B cells and plasma cells located in tumours or in tumour-draining lymph nodes can have important roles in shaping antitumour immune responses. (nature.com)
  • its cells also show a lesser degree of anaplasia than those of a malignant tumor do. (thefreedictionary.com)
  • A rare, rapidly growing malignant tumor of neuroectodermal cell origin that arises in the chest and lungs It shares a common neuroectodermal origin with Ewing sarcoma (of bone). (tabers.com)
  • 12 The resistive index (RI) and pulsatility index (PI) have been used in the evaluation of ovarian masses because of the expected low impedance and high diastolic blood flow seen in blood vessels supplying the malignant tumor. (appliedradiology.com)
  • In vitro studies revealed that iron oxide nanoparticles are preferentially phagocytosed by TAMs but not by malignant tumor cells. (aacrjournals.org)
  • The majority of Brenner tumors are most frequently found incidentally on pelvic examination or at laparotomy . (wikidoc.org)
  • Early clinical features of surface epithelial-stromal tumor include pelvic fullness, abdominal distension, and abdominal pain. (wikidoc.org)
  • Also recall that the "coffee bean nuclei" are the nuclear grooves exceptionally pathognomonic to the sex cord stromal tumor, the ovarian granulosa cell tumor, with the fluid-filled spaces Call-Exner bodies between the granulosa cells. (wikipedia.org)
  • The absence of TERT promoter mutations in Brenner tumors suggests that despite the morphologic and some immunophenotypical resemblance to non-neoplastic and neoplastic transitional epithelium, Brenner tumors may exhibit a molecularly distinct pathogenesis. (elsevier.com)
  • Neoplastic brain tumors may be benign or malignant. (tabers.com)
  • As in normal and neoplastic bladder urothelium, urothelial markers, including uroplakin III, CK13, and CK20, were detected in the epithelial nests of Brenner tumors. (qxmd.com)
  • when neoplastic, possibly constituting comprising one of the components of the Brenner tumor. (drugs.com)
  • Ovarian functional and neoplastic tumors. (mhmedical.com)
  • Our data indicate that the Food and Drug Administration (FDA)-approved iron oxide nanoparticle compound ferumoxytol (Feraheme) is preferentially phagocytosed by TAMs, but not by neoplastic tumor cells. (aacrjournals.org)
  • Most malignant brain tumors are metastatic, with 20% to 40% of patients with cancer developing brain metastasis. (tabers.com)
  • Tumor-to-Tumor Metastasis of Colorectal Adenocarcinoma to Ovarian Cystadenofibroma: A Case Report and Review of the Literature. (amedeo.com)
  • Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma. (amedeo.com)
  • The following Tumor (T), Lymph node (N) and Metastasis (M) stage and FIGO stage are based on the AJCC Cancer Staging Manual, 8th Edition . (jhu.edu)
  • Studies in transgenic mouse models of mammary carcinogenesis revealed that tumor-associated macrophages (TAM) promote tumor growth and enhance pulmonary metastasis by high-level expression of epidermal growth factor (EGF) and activation of EGF-regulated signaling in mammary epithelial cells (MEC) critical for invasive tumor growth and metastatic dissemination ( 4 ). (aacrjournals.org)
  • Advances over the past decade suggest a need to reassess the distribution of ovarian surface epithelial tumors. (nih.gov)
  • Ovarian Brenner tumour: a morphologic and immunohistochemical analysis suggesting an origin from fallopian tube epithelium. (librepathology.org)
  • Thus, it has been proposed that serous tumors arise from the implantation of epithelium (benign or malignant) from the fallopian tube. (nih.gov)
  • A low-grade malignant, sex cord-stromal tumor composed of granulosa cells often with a variable number of fibroblasts and theca cells. (jhu.edu)
  • [1] [2] The pathogenesis of surface epithelial-stromal tumor is characterized by the overgrowth of the ovarian surface epithelium. (wikidoc.org)
  • The prevalence of surface epithelial-stromal tumor is approximately 3 per 100,000 individuals worldwide. (wikidoc.org)
  • Surface epithelial-stromal tumor is more commonly observed among postmenopausal women. (wikidoc.org)
  • The mainstay of therapy for surface epithelial-stromal tumor is platinum-based chemotherapy . (wikidoc.org)
  • According to the American College of Radiology, secondary prevention of surface epithelial-stromal tumor may include periodical pelvis or transvaginal ultrasound with or without Doppler. (wikidoc.org)
  • Surface epithelial-stromal tumor was first discovered by Taylor in 1929. (wikidoc.org)
  • The HYAL1-3 mutation has been associated with the development of surface epithelial-stromal tumor. (wikidoc.org)
  • Ovarian Sclerosing Stromal Tumor and Mullerian Cyst in an 11-yr-old Girl: A Case Report and Review of the Literature. (amedeo.com)
  • 1-9) Roth and Ramzy (11,12) and others (4,13) have also described sclerosing stromal tumor or thecoma with signet ring cell transformation and ovarian epithelial or granulosa cell tumors with signet ring cell change in the nonneoplastic stroma. (thefreedictionary.com)
  • Thus, it appears that the only true urothelial-type ovarian neoplasm is the Brenner tumor, whereas ovarian TCC most likely represents a poorly differentiated adenocarcinoma with a morphologic transitional cell pattern. (qxmd.com)
  • Our case: Brenner tumor with struma ovarii on histology. (blogspot.com)
  • Histology of the ovarian tumour showed thyroid tissue characteristic of struma ovarii (Figure 1 ). (hindawi.com)
  • Struma ovarii are ovarian tumors composed of thyroid tissue, with 5-10% being malignant. (appliedradiology.com)
  • Animal Models for Studying Tumor Microenvironment (TME) and Resistance to Lymphocytic Infiltration. (bioportfolio.com)
  • Here we summarize our current knowledge of the roles of B cells and antibodies in the tumour microenvironment. (nature.com)
  • p53 also promotes cellular senescence, a tumor suppressive program that involves stable cell cycle arrest and secretion of factors that modify the tissue microenvironment. (pubmedcentralcanada.ca)
  • Hence, p53 can act non-cell autonomously to suppress tumorigenesis by promoting an anti-tumor microenvironment, in part, through secreted factors that modulate macrophage function. (pubmedcentralcanada.ca)
  • The majority of Brenner tumors are unilateral. (wikidoc.org)
  • The vast majority of Brenner tumors is benign, while only 1% is malignant and associated with a poor prognosis. (elsevier.com)
  • If left untreated, the minority of patients with Brenner tumor may progress to develop local invasion, lymphadenopathy, ascites, or metastases. (wikidoc.org)
  • Common complications of Brenner tumor include peritoneal metastases, or ovarian torsion. (wikidoc.org)
  • Pattern and distribution of bone metastases in common malignant tumors. (springer.com)
  • Predictive value of Tokuhashi scoring Systems in spinal metastases, focusing on various primary tumor groups evaluation of 448 patients in the Aarhus spinal metastases database. (springer.com)
  • The combination of α-GC or a more potent analog with anti-DR5 mAb and anti-CD137 mAb (termed NKTMab therapy) eradicated established tumors and metastases in a majority of mice. (jimmunol.org)
  • We think that activating TET1 may be a general therapeutic strategy for many malignancies," Brenner says. (medindia.net)
  • Epithelial tumors account for nearly 85% to 90% of all ovarian malignancies. (appliedradiology.com)
  • Recently, increasing attention has been brought to the possibility that many potential precursor or premalignant lesions, though composed of microscopically-and genetically-cancerous cells, do not advance to malignant tumors or lethal malignancies. (mdpi.com)
  • Guidelines for the management of tumour lysis syndrome in adults and children with haematological malignancies on behalf of the British Committee for Standards in Haematology. (medscape.com)
  • Borderline ovarian tumor(BOT) is a distinct well established yet controversial entity among ovarian tumors of epithelial origin, which is biologically and histopathologically intermediate between frankly malignant and obviously benign ovarian tumors. (laparoscopyhospital.com)
  • Benign ovarian stromal tumors associated with free peritoneal fluid. (medscape.com)
  • KRAS promotes cancer formation not only by driving cell growth and division, but also by turning off protective tumor suppressor genes, which normally limit uncontrolled cell growth and cause damaged cells to self-destruct. (medindia.net)
  • A new University of Iowa study provided a deeper understanding of how KRAS turns off tumor suppressor genes and identifies a key enzyme in the process. (medindia.net)
  • In KRAS-driven cancers, tumor suppressor genes are turned off, or silenced, because the DNA that controls their expression is modified by methylation. (medindia.net)
  • We found that one of the ways tumor suppressor genes become methylated when KRAS is activated is that an 'eraser' of the methyl marks - the enzyme called TET1 - is no longer expressed," explains Charles Brenner, Ph.D., the Roy J. Carver Chair of Biochemistry in the UI Carver College of Medicine and senior study author. (medindia.net)
  • Brenner and lead study author Bo-Kuan Wu, PhD, found that adding TET1 back to these cells reactivates tumor suppressor genes and is enough to reduce their abnormal proliferation. (medindia.net)
  • Jefferson Scientists Hopeful That Understanding Tumor-Suppressor Protein Function May Someday Lead To. (bio-medicine.org)
  • Dr. Brenner and his colleagues used a combined genetic, biochemical and crystallographic approach to gain information about the function of the tumor-suppressor protein, Fhit, the product of the FHIT gene. (bio-medicine.org)
  • A lot of data has been collected for NPRL2 (also called Tumor suppressor candidate 4 - TUSC4), which was suggested to be a tumor suppressor more than a decade ago 30 . (nature.com)
  • The p53 tumor suppressor can restrict malignant transformation by triggering cell-autonomous programs of cell cycle arrest or apoptosis. (pubmedcentralcanada.ca)
  • The p53 tumor suppressor acts as a central node in cellular stress response programs induced by DNA damage and oncogene activation ( Vousden and Prives, 2009 ). (pubmedcentralcanada.ca)
  • Central nervous system changes occur as the lesions invade and destroy tissue, and, because the tumors compress the brain, cranial nerves, and cerebral blood vessels, the compression causes cerebral edema and increased intracranial pressure (ICP). (tabers.com)
  • While not all STICs may transform into malignant tumors, these lesions are clearly associated with increased risk for HGSC. (mdpi.com)
  • 20% of benign, 30% of borderline, and 66% of malignant tumors are bilateral (affect both ovaries). (bionity.com)
  • The five year survival rate of borderline and malignant tumors confined to the ovaries are 100% and 70% respectively. (bionity.com)
  • The ovaries can be the site for various primary tumors and also the presenting site of metastatic disease. (cytojournal.com)
  • Scoring system for the preoperative evaluation of metastatic spine tumor prognosis. (springer.com)
  • As a patient, the stage of your ovarian cancer tumor will guide your treatment and have an impact on prognosis. (jhu.edu)
  • These data indicate that tumor enhancement with clinically applicable iron oxide nanoparticles may serve as a new biomarker for long-term prognosis, related treatment decisions, and the evaluation of new immune-targeted therapies. (aacrjournals.org)
  • [2] Women who have any type of ovarian cancer, including a malignant Brenner tumor, may want to ask their health care professional about genetic counseling because ovarian cancer is sometimes associated with a gene mutation that can be inherited in families. (cdc.gov)
  • For this reason necrosis and ulceration are characteristic of malignant tumors. (thefreedictionary.com)
  • Gadolinium contrast is not necessary as it does not give additional information over noncontrast studies, though some current researchers argue that dynamic, contrast enhanced MRI may help determine the amount of necrosis within the tumor, thus help in determining response to treatment prior to surgery. (bionity.com)
  • Brenner D, Blaser H, Mak TW (2015) Regulation of tumour necrosis factor signalling: live or let die. (springer.com)
  • Growing evidence suggests that proinflammatory cytokines (PICs), such as interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNFα), are induced in the spinal cord under various injury conditions and contribute to pain hypersensitivity. (jneurosci.org)
  • We describe this case and review the literature on metastatic tumors to the cervix. (elsevier.com)
  • The NOMS framework: approach to the treatment of spinal metastatic tumors. (springer.com)
  • Atlas of Tumor Pathology. (nii.ac.jp)
  • In addition a tumor was found in liver segment 3 which was completely excised and sent to pathology for frozen section. (forsurgeons.net)
  • Most notably to characterize pediatric tumor pathology, evaluate abnormalities of the juvenile reproductive system, demonstrate the histologic and ultrastructural changes of metabolic disorders on specific organs, and elucidate new scientific techniques to aid in the study of childhood disease. (stanford.edu)
  • Although animal studies require higher chemical concentrations than predicted for human exposure, this study demonstrates that TCS acts as a HCC tumor promoter and that the mechanism of TCS-induced mouse liver pathology may be relevant to humans. (pnas.org)
  • To determine whether gene-modified T cells could induce antitumor effects without associated autoimmune pathology, we assessed the ability of T cells expressing an anti-Her-2 chimeric receptor to eradicate tumor in Her-2 transgenic mice that express human Her-2 as a self-antigen in brain and mammary tissues. (aacrjournals.org)
  • Primary malignant brain tumors make up from 10% to 30% of adult cancers and about 20% in children, but any of these tumors may occur at any age. (tabers.com)
  • Estrogen receptor (ER) and Progesterone receptor (PR) are prognostic indicators for a number of epithelial tumors and may play the same role in ovarian cancers. (bireme.br)