Pathological processes of the BREAST.
A common and benign breast disease characterized by varying degree of fibrocystic changes in the breast tissue. There are three major patterns of morphological changes, including FIBROSIS, formation of CYSTS, and proliferation of glandular tissue (adenosis). The fibrocystic breast has a dense irregular, lumpy, bumpy consistency.
In humans, one of the paired regions in the anterior portion of the THORAX. The breasts consist of the MAMMARY GLANDS, the SKIN, the MUSCLES, the ADIPOSE TISSUE, and the CONNECTIVE TISSUES.
An adenoma containing fibrous tissue. It should be differentiated from ADENOFIBROMA which is a tumor composed of connective tissue (fibroma) containing glandular (adeno-) structures. (From Dorland, 27th ed)
Tumors or cancer of the human BREAST.
A benign neoplasm composed of glandular and fibrous tissues, with a relatively large proportion of glands. (Stedman, 25th ed)
An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST.
Radiographic examination of the breast.
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
A noninvasive (noninfiltrating) carcinoma of the breast characterized by a proliferation of malignant epithelial cells confined to the mammary ducts or lobules, without light-microscopy evidence of invasion through the basement membrane into the surrounding stroma.
A fluid-filled closed cavity or sac that is lined by an EPITHELIUM and found in the BREAST. It may appear as a single large cyst in one breast, multifocal, or bilateral in FIBROCYSTIC BREAST DISEASE.
The conic organs which usually give outlet to milk from the mammary glands.
The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.
A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
A infiltrating (invasive) breast cancer, relatively uncommon, accounting for only 5%-10% of breast tumors in most series. It is often an area of ill-defined thickening in the breast, in contrast to the dominant lump characteristic of ductal carcinoma. It is typically composed of small cells in a linear arrangement with a tendency to grow around ducts and lobules. There is likelihood of axillary nodal involvement with metastasis to meningeal and serosal surfaces. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1205)
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Removal and examination of tissue obtained through a transdermal needle inserted into the specific region, organ, or tissue being analyzed.
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of estrogen receptors in breast cancer patients has become clinically important.
Use of ultrasound for imaging the breast. The most frequent application is the diagnosis of neoplasms of the female breast.
The nursing of an infant at the breast.
Application of fingers with light pressure to the surface of the body to determine consistence of parts beneath in physical diagnosis; includes palpation for determining the outlines of organs.
INFLAMMATION of the BREAST, or MAMMARY GLAND.
Specific proteins found in or on cells of progesterone target tissues that specifically combine with progesterone. The cytosol progesterone-receptor complex then associates with the nucleic acids to initiate protein synthesis. There are two kinds of progesterone receptors, A and B. Both are induced by estrogen and have short half-lives.
Surgical procedure to remove one or both breasts.
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Ability of neoplasms to infiltrate and actively destroy surrounding tissue.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.
The physiological period following the MENOPAUSE, the permanent cessation of the menstrual life.
Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
The number of offspring a female has borne. It is contrasted with GRAVIDITY, which refers to the number of pregnancies, regardless of outcome.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Any neoplasms of the male breast. These occur infrequently in males in developed countries, the incidence being about 1% of that in females.
The periodic shedding of the ENDOMETRIUM and associated menstrual bleeding in the MENSTRUAL CYCLE of humans and primates. Menstruation is due to the decline in circulating PROGESTERONE, and occurs at the late LUTEAL PHASE when LUTEOLYSIS of the CORPUS LUTEUM takes place.
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
The period before MENOPAUSE. In premenopausal women, the climacteric transition from full sexual maturity to cessation of ovarian cycle takes place between the age of late thirty and early fifty.
Liquid components of living organisms.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
The first MENSTRUAL CYCLE marked by the initiation of MENSTRUATION.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.
A cell line derived from cultured tumor cells.
Implants used to reconstruct and/or cosmetically enhance the female breast. They have an outer shell or envelope of silicone elastomer and are filled with either saline or silicone gel. The outer shell may be either smooth or textured.
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
An intracellular proteinase found in a variety of tissue. It has specificity similar to but narrower than that of pepsin A. The enzyme is involved in catabolism of cartilage and connective tissue. EC 3.4.23.5. (Formerly EC 3.4.4.23).
A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.
Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
The inspection of one's breasts, usually for signs of disease, especially neoplastic disease.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Elements of limited time intervals, contributing to particular results or situations.
One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
Compounds that interact with PROGESTERONE RECEPTORS in target tissues to bring about the effects similar to those of PROGESTERONE. Primary actions of progestins, including natural and synthetic steroids, are on the UTERUS and the MAMMARY GLAND in preparation for and in maintenance of PREGNANCY.
Organized periodic procedures performed on large groups of people for the purpose of detecting disease.
A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.
Organized services in a hospital which provide medical care on an outpatient basis.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

Measurement of prostate-specific antigen in detection of benign or malignant breast disease in women. (1/757)

Using a highly sensitive chemiluminescent enzyme immunoassay, we have evaluated the measurement of serum prostate-specific antigen (PSA) as a potential diagnostic test for differentiation between women with breast cancer and those with benign breast disease. In a controlled study consisting of 284 women with well-documented patient files and matched for age and long-term place of residence, serum samples collected from 90 women with histologically confirmed breast cancer, 94 women with benign breast disease and 100 controls were analysed. Serum total PSA levels in benign breast disease and cancer patients are not statistically different from those of healthy controls. Total PSA levels decrease with age in normal controls and breast cancer patients but not in those with benign breast disease. The total PSA concentration decreases after menopause in healthy women, though not in patients with breast cancer or benign breast disease. Total PSA bore no relation to the histological type or grade of the tumour or the disease stage of the breast cancer patients. In benign breast disease, all mastopathy patients had normal total PSA, whereas elevation of the values was observed in 7% of fibroadenoma patients. Our results show that serum total PSA cannot be used to distinguish between healthy women and/or women with breast cancer or benign breast disease.  (+info)

Systemic multifocal fibrosclerosis. (2/757)

We describe a case of hydronephrosis as a result of retroperitoneal fibrosis in a patient who had previous sclerosing lobulitis of the breast. To the best of our knowledge this is the first reported association between these two conditions in the english literature. We presume these conditions are linked and unify them under the general heading of systemic multifocal fibrosclerosis.  (+info)

Screening for breast cancer: time, travel, and out-of-pocket expenses. (3/757)

BACKGROUND: We estimated the personal costs to women found to have a breast problem (either breast cancer or benign breast disease) in terms of time spent, miles traveled, and cash payments made for detection, diagnosis, initial treatment, and follow-up. METHODS: We analyzed data from personal interviews with 465 women from four communities in Florida. These women were randomly selected from those with a recent breast biopsy (within 6-8 months) that indicated either breast cancer (208 women) or benign breast disease (257 women). One community was the site of a multifaceted intervention to promote breast screening, and the other three communities were comparison sites for evaluation of that intervention. All P values are two-sided. RESULTS: In comparison with time spent and travel distance for women with benign breast disease (13 hours away from home and 56 miles traveled), time spent and travel distance were statistically significantly higher (P<.001) for treatment and follow-up of women with breast cancer (89 hours and 369 miles). Personal financial costs for treatment of women with breast cancer were also statistically significantly higher (breast cancer = $604; benign breast disease = $76; P < .001) but were statistically significantly lower for detection and diagnosis (breast cancer = $170; benign breast disease = $310; P < .001). Among women with breast cancer, time spent for treatment was statistically significantly lower (P = .013) when their breast cancer was detected by screening (68.9 hours) than when it was detected because of symptoms (84.2 hours). Personal cash payments for detection, diagnosis, and treatment were statistically significantly lower among women whose breast problems were detected by screening than among women whose breast problems were detected because of symptoms (screening detected = $453; symptom detected = $749; P = .045). CONCLUSION: There are substantial personal costs for women who are found to have a breast problem, whether the costs are associated with problems identified through screening or because of symptoms.  (+info)

Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast. (4/757)

A centrosomal serine/threonine kinase, AIK1(3)/breast tumor amplified kinase/aurora2, which was recently identified as an oncogene, shows high amino acid identity with chromosome segregation kinases, fly Aurora, and yeast Ipl1. Immunohistochemical analyses of invasive ductal adenocarcinomas of the breast revealed that overexpression of AIK1 was observed in 94% of the cases, irrespective of the histopathological type, whereas the protein was not detected in normal ductal and lobular cells. Benign breast lesions including fibrocystic disease and fibroadenoma (epithelial components) displayed weakly detectable AIK1 expression in part of the lesions. This is the first immunohistochemical report of AIK1 expression in primary human breast carcinomas. Although the physiological function(s) of AIK1 kinase during cell division remains to be determined, the markedly high positivity of AIK1 staining in the cancer lesions suggested a possible involvement of its overexpression in the tumorigenesis of some of breast cancer cells.  (+info)

Comparison of mammographically guided breast biopsy techniques. (5/757)

OBJECTIVE: To determine which mammographically guided breast biopsy technique is the most efficient in making a diagnosis in women with suspicious mammograms. SUMMARY BACKGROUND DATA: Mammographically guided biopsy techniques include stereotactic 14-gauge core-needle biopsy (SC bx), stereotactic 11-gauge suction-assisted core biopsy (Mammotome [Mbx]), stereotactic coring excisional biopsy (Advanced Breast Biopsy Instrument [ABBI]), and wire-localized biopsy (WL bx). Controversy exists over which technique is best. METHODS: All patients undergoing any one of these biopsy methods over a 15-month period were reviewed, totaling 245 SC bx, 107 Mbx, 104 ABBI, and 520 WL bx. Information obtained included technical success, pathology, discordant pathology, and need for open biopsy. RESULTS: Technical success was achieved in 94.3% of SC bx, 96.4% of Mbx, 92.5% of ABBI, and 98.7% of WL bx. The sensitivity and specificity were 87.5% and 98.6% for SC bx, 87.5% and 100% for Mbx, and 100% and 100% for ABBI. Discordant results or need for a repeat biopsy occurred in 25.7% of SC bx, 23.2% of Mbx, and 7.5% of ABBI biopsies. In 63.6% of ABBI and 50.9% of WL bx, positive margins required reexcision; of the cases with positive margins, 71.4% of ABBI and 70.4% of WL bx had residual tumor in the definitive treatment specimen. CONCLUSION: Although sensitivities and specificities of SC bx and Mbx are good, 20% to 25% of patients will require an open biopsy because a definitive diagnosis could not be reached. This does not occur with the ABBI excisional biopsy specimen. The positive margin rates and residual tumor rates are comparable between the ABBI and WL bx. The ABBI avoids operating room and reexcision costs; therefore, in appropriately selected patients, this appears to be the most efficient method of biopsy.  (+info)

In vitro estrogen-binding by human breast carcinomas. (6/757)

Patients whose breast carcinomas possess only low concentrations of a receptor molecule that binds estrogens with high affinity are unlikely to respond to hormonal manipulative therapy when the disease recurs. The estrogen-binding capacity of 106 breast carcinomas was measured by an in vitro method and was expressed per milligram wet weight and in some cases related to the concentration of deoxyribonucleic acid (DNA) of the tumours. The ability of tumors to bind 3H-estradiol ranged from 0 to 1.3 fm/mg in pre- and perenopausal women, and from 0 to 16.8 fm/mg in postmenopausal women. Menopausal status or serum concentrations of endogenous estrogen, or both, should therefore be considered when tumours are classified into low and high estrogen-binding capacity. It is not necessary to carry out Scatchard analysis for every tumour, and expressing estradiol binding on the basis of DNA concentration may be preferable to expressing in on a wet-weight basis.  (+info)

MammoWeb continuing medical education (CME): a web-based breast imaging CME program. (7/757)

The ubiquity of the world-wide web allows unique educational opportunities for continuing medical education (CME). We have designed a comprehensive breast imaging CME curriculum to permit individual physicians in their homes or offices to use personal computers to ease the burden of this process. Category 1 CME credits can be earned off-hours without having the physician travel out of town. In addition, since the course is computer-based, the overall costs to the participant are substantially reduced. The program can be updated on an ongoing basis to include new technology or to provide additional information requested by the users.  (+info)

Identification of women with early breast cancer by analysis of p43-positive lymphocytes. (8/757)

Regular screening mammographies and increasing knowledge of high-risk groups have resulted in an improvement in the rate of detection of smaller malignant lesions. However, uncertain minimal mammographic features frequently require further costly and often uncomfortable investigation, including repeat radiological controls or surgical procedures, before cancerous lesions can be identified. Placental isoferritin (p43), a protein with immunosuppressive effects, has been detected on the surface of lymphocytes taken from peripheral blood in patients with breast cancer. In this study we evaluated the sensitivity and specificity of the expression of p43-positive lymphocytes as a marker in early stage breast cancer and also investigated its expression on T-cell subpopulations. The presence of p43-positive lymphocytes was investigated using the monoclonal antibody CM-H-9 and flow cytometry in 76 women with controversial, non-palpable mammographic findings who were undergoing surgical biopsy. Patients with early breast cancer (n = 48) had significantly higher p43-positive cell values (median 3.83%, range 0.98-19.4) than patients with benign lumps (n = 28, median 1.43%, range 0.17-3.7) or controls (n = 22, median 1.3%, range 0.4-1.87) (P < 0.0001). At a cut-off level of 2% p43-positive cells a sensitivity of 91.7% and a specificity of 89.3% for detection of breast cancer could be reached. While the median ratio of total CD4+/CD8+ cells was 2.6, a ratio of 1.3 was found for the p43-positive subpopulation (P < 0.001), thus indicating a significant link between p43 and CD8+ cells. The determination of p43-positive lymphocytes in peripheral blood could serve as an additional diagnostic tool in patients with controversial mammographic findings and could also reduce the need for cost-intensive and often uncomfortable management of these patients.  (+info)

TY - JOUR. T1 - A randomized controlled trial of calcium plus vitamin D supplementation and risk of benign proliferative breast disease. AU - Rohan, Thomas E.. AU - Negassa, Abdissa. AU - Chlebowski, Rowan T.. AU - Ceria-Ulep, Clementina D.. AU - Cochrane, Barbara B.. AU - Lane, Dorothy S.. AU - Ginsberg, Mindy S.. AU - Wassertheil-Smoller, Sylvia. AU - Page, David L.. PY - 2009/7. Y1 - 2009/7. N2 - Experimental evidence provides strong support for anti-carcinogenic effects of calcium and vitamin D with respect to breast cancer. Observational epidemiologic data also provide some support for inverse associations with risk. We tested the effect of calcium plus vitamin D supplementation on risk of benign proliferative breast disease, a condition which is associated with increased risk of breast cancer. We used the Womens Health Initiative randomized controlled trial. The 36,282 participants were randomized either to 500 mg of elemental calcium as calcium carbonate plus 200 IU of vitamin D 3 ...
Preneoplasia of the Breast A New Conceptual Approach to Proliferative Breast Disease by Professor, Dr. Werner Boecker | Buy Books at LoveReading.co.uk Safe and accurate preoperative diagnosis of breast lesions is crucial to spare patients unnecessary, disfiguring operations. The book covers the clinical, radiological and histological diagnosis of benign proliferative breast disease and precursor lesions of breast cancer. It focuses on a new immunohistochemical method based on an innovative progenitor cell concept...Find out more
Benign Breast Disease Anatomical Chart -9781587796746 : Benign Breast Disease Anatomical Chart Pub Date: June 2003 Product Type: Print
The resident in the Breast Diseases PGY3 Enhanced Skills Program will:. 1. Demonstrate expertise in the identification, diagnosis and management of common and uncommon family medicine problems. 2. Engage patients in health promotion, including prevention and screening according to evidence based family medicine guidelines. 3. Be able to describe the pathological characteristics of benign and malignant breast disease.. 4. Demonstrate competence in breast assessment and the ability to investigate and manage common breast-related patient presentations such as:. a. A palpable breast mass or skin change. b. Indeterminate breast imaging abnormality. c. Nipple discharge. d. Breast pain. e. Pathological indicators of high-risk or patient with strong family history of breast cancer. 5. Demonstrate expertise in the assessment and clinical management of benign breast diseases such as:. a. Cysts. b. Fibroepithelial lesions. c. Mastitis or breast abscess. d. Atypia or lobular carcinoma in situ. e. ...
J. Michael Dixon, MBChB,MD, FRCS, FRCSEd, FRCP, Edinburgh Breast Unit,Western General Hospital, Edinburgh, Scotland.. The incidence of breast cancer increases with advancing age, and the relative frequency of benign breast disease (BBD) decreases. Therefore, all breast symptoms or abnormalities should be assessed with triple testing (clinical examination, imaging, +/-percutaneous needle biopsy if a localized lesion is identified) to establish a diagnosis.The spectrum of BBD changes substantially from about age 45 onwards.We review some of the benign conditions that occur in older women, such as cysts and duct ectasia, and describe clinical features and management.We also discuss specific BBDs that may be encountered more frequently and in a much older population of women than was previously identified, a consequence of both increased incidence of BBD due to past use of hormone replacement therapy and improved detection ...
Stromal fibroblasts are important for normal breast homeostasis and regulation of epithelial growth; however, this regulatory function is altered during carcinogenesis. To study the role of fibroblasts in the development of breast cancer, fibroblasts derived from normal breast (NAFs) were incorporated into the MCF10AT xenograft model of progressive proliferative breast disease. The persistence of human NAFs in xenografts was established by intracellular labeling and tyramide-coupled fluorescent in situ hybridization.
The number of breast cancer survivors is increasing due to the increased use of mammographic screening and adjuvant therapy. <BR>Adjuvant therapy for breast cancer increases the severity of menopausal symptoms and the incidence of amenorrhoea. <BR>Overall data on risk of HRT on breast cancer survivors are inconclusive. <BR>SSRIs, gabapentin or clonidine may be the best of the non-hormonal agents for treatment of vasomotor symptoms. <BR>Non-hormonal agents are often ineffective and one-third of women are prepared to use HRT. <BR>HRT is the most efficacious treatment and is an option in women with severe vasomotor symptoms refractory to non-hormonal agents. <BR>Benign breast disease is a risk factor for breast cancer depending on histology and family history. <BR>Women with a family history of breast cancer are at increased risk depending on the degree and number of relatives and require close surveillance. <BR>HRT is not thought to increase the risk further
TY - JOUR. T1 - Benign breast disease. T2 - Emerging findings in a diverse population. AU - Hartmann, Lynn C.. AU - Ghosh, Karthik. PY - 2007/3. Y1 - 2007/3. UR - http://www.scopus.com/inward/record.url?scp=33847091224&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=33847091224&partnerID=8YFLogxK. U2 - 10.1111/j.1524-4741.2007.00387.x. DO - 10.1111/j.1524-4741.2007.00387.x. M3 - Article. C2 - 17319850. AN - SCOPUS:33847091224. VL - 13. SP - 113. EP - 114. JO - Breast Journal. JF - Breast Journal. SN - 1075-122X. IS - 2. ER - ...
A Wayne State University researcher has identified characteristics in benign breast disease associated with future cancer risk in African-American women.
To evaluate the spectrum of breast diseases and their association with presenting complains of patients. It was a cross sectional study conducted from 1st January 2010 - 30th December 2012. A total of 254 breast specimens of patients, who were admitted in Civil Hospital Karachi with breast complaints, were included. Specimens were collected either from mastectomy, lumpectomy or needle biopsy from the admitted patients. Informed written consent was taken from all the patients. All patients with primary breast diseases were included. Patients undergoing chemotherapy or with secondary breast disease and slides with insufficient specimen were excluded. All data was entered and analyzed through SPSS 19. There were 254 breast lesions, histologically diagnosed in 3 year review period. The overall mean age of patients with breast lesion was 25.18, SD ± 11.73 with a wide age range of 12-74 years. Most common cases identified are benign 191(75.3%), followed by inflammatory 30(11.8%) and malignant lesions 30(11.8
In this issue of American Family Physician, Morrow1 discusses the evaluation of three common breast problems: breast pain, nipple discharge and breast mass. I agree with the authors assertion that the goal of the evaluation is to exclude cancer and treat symptoms.. It seems prudent to include a review of risk factors in the efforts to exclude breast cancer. Risk factors include age, family history of breast cancer, early menarche, older age at first full-term pregnancy, nulliparity, presence or history of benign breast disease, and late menopause. Potentially modifiable risk factors include higher body mass index, heavy use of alcohol, use of oral contraceptives and not having breast-fed.2. The psychosocial impact of breast problems on patients is a frequently overlooked aspect of the evaluation of common breast problems. Because breast problems cause such a high level of distress for patients, particularly before a definitive diagnosis is obtained,3 physical examination alone may not provide ...
CBS News) -- New research shows alcohol might be linked to benign breast disease in young women. A new study that looked at 16 to 23-year-olds found the more they drank, the higher their risk.. Benign breast disease is a mixed group of different conditions like lumps or cysts, and they can be a warning sign. Theyre just thought the be a marker for increased risk of breast cancer, said Dr. Rulla Tamimi of the Brigham and Womens Hospital study. We consider them altogether; women have about a 50 percent increased risk of developing breast cancer.. Young women who drank six to seven days per week had more than five times the risk of benign breast disease than young women who never drank. Women who drank three to five days per week had three times the risk.. I think this really says that perhaps women should really consider modifying their alcohol intake, said Tamimi.. The findings are a wake-up call after a study last year that found binge drinking among college women in their early 20s ...
NEW SCAN ALMOST 100% ACCURATE IN IDENTIFYING BREAST CANCER. An estimated 1.4 million women undergo breast biopsies every year in the United States for abnormal findings on their mammograms, and approximately 85 percent of these suspicious mammographic findings will turn out to be benign following biopsy.. At the present time, breast imaging technology has not advanced enough to replace biopsy for most women with suspicious abnormalities noted on mammograms, or for women who develop palpable breast lumps. For example, MRI scans can detect 95 to 98 percent of early breast cancers, but MRI is also associated with a very high false-positive rate, in which as many as 25 percent of identified abnormalities turn out, after biopsy, to be benign. In an ideal world, a perfect breast scan would accurately identify 100 percent of cancers and 100 percent of benign breast lesions, but such a scan does not exist at this time. However, a new technology for scanning small cores of breast tissue removed ...
Dr. Hartmann and her co-investigators were heartened to find convincing evidence that women with the most common, non-proliferative forms of benign findings had no increased risk of developing breast cancer -- as long as they did not have a strong family history of breast cancer. However, for proliferative and atypical types, the opposite was true, and these lesions pointed to an increased risk of a future breast cancer, even when the family history of breast cancer was negative. Dr. Hartmann and her colleagues say continued studies of this kind are necessary to help understand the process of breast cancer development.. The study population of 9,087 women was drawn from the Mayo Clinic Surgical and Pathology Indices, identifying women ages 18 to 85, who had a biopsy of a benign breast lesion during a 25-year period from Jan. 1, 1967, through Dec. 31, 1991. Family histories were obtained at time of follow-up and from Mayo medical record questionnaires.. All benign breast samples were evaluated by ...
Background : We studied the associations between c-erbB-2 protein overexpression and p53 protein accumulation in benign breast tissue and the risk of subsequent breast cancer. Methods : We conducted a case-control study nested within the cohort of 4888 women in the National Breast Screening Study NBSS who were diagnosed with benign breast...
Benign breast lesions with malignant clinical and mammographic presentations.: Nine cases of benign breast disease in which mammograms had been false-positive w
Assessed on that basis of pre- and post-treatment evaluation with RPFNA (random periareolar fine needle aspiration). All subjects received a prescription for lovastatin 80 mg/day, to be taken as 40 mg twice-a-day.. Cytology was qualitatively and quantitatively, using the Masood semiquantitative scale to assign a number to each specimen, with higher numbers indicating increasing degrees of abnormality, as follows:. 06-10 Non-proliferative breast disease (NPBD). 11-14 Proliferative breast disease without atypia (PBD-A). 15-18 Proliferative breast disease with atypia (PBD+A). 19-24 Carcinoma in situ and invasive cancer (CIS/IC). If no cells could be obtained after multiple RPFNA attempts, the classification was acellular.. Change from NPBD to PBD-A was considered Unfavorable.. Change from NPBD to Acellular was considered Equivocal.. Change from PBD-A to NPBD was considered Favorable. ...
RESULTS: BS-seq demonstrated that the NBPF1 methylation levels in breast cancer patients were higher than those in patients with benign breast disease and healthy controls. The MSP results showed that the methylation rates of two sites in the NBPF1 promoter were 67.1%and 61.4%in breast cancer patients, 48.2% and 59.6% in patients with benign breast disease, and 40.9% and 48.1% in healthy controls, respectively. The methylation rates of one site were significantly different among the three groups (p , .05), with the highest rate in breast cancer patients. Moreover, there was no statistically significant correlation between the NBPF1 promoter methylation and the major clinicopathological features of the patients ...
Vibro-acoustography (VA) is a newly developed imaging technology that is based on low-frequency vibrations induced in the object by the radiation force of ultrasound. VA is sensitive to the dynamic characteristics of tissue. Here, we evaluate the performance of VA in identifying benign lesions and compare the results to those of mammography. An integrated mammography-VA system designed for in vivo breast imaging was tested on a group of female volunteers, age ≥ 18 years, with suspected breast lesions based on clinical examination. A set of VA scans was acquired after each corresponding mammography. Most lesions were classified as benign based on their histological results. However, in 4 cases, initial diagnosis based on clinical imaging determined that the lesions were cysts. These cysts were aspirated with needle aspiration and disappeared completely under direct ultrasound visualization. Therefore, no biopsies were performed on these cases and lesions were classified as benign based on clinical
Contributed by Professor Kefah Mokbel, lead breast surgeon, The Princess Grace Hospital, and honorary consultant breast surgeon, St Georges Hospital.
Women with benign proliferative breast disease (BPBD) are at increased risk for developing breast cancer. Evidence suggests that accumulation of adipose tissue can influence breast cancer development via hyperinsulinemia, increased estrogen, and/or inflammation. However, there are limited data investigating these pathways with respect to risk of BPBD. We evaluated serologic markers from these pathways in a case-control study of postmenopausal women nested within the Womens Health Initiative Clinical Trial. Cases were the 667 women who developed BPBD during follow-up, and they were matched to 1,321 controls. Levels of insulin, estradiol, C-reactive protein (CRP), and adiponectin were measured in fasting serum collected at baseline. Conditional logistic regression models were used to estimate ORs for the association of each factor with BPBD risk. Among nonusers of hormone therapy, fasting serum insulin was associated with a statistically significant increase in risk of BPBD (OR for highest vs. ...
Did you narrow your search by selecting from the Narrow By boxes? Try removing those filters from the bar above to broaden the search. ...
|i|Introduction|/i|. Mastalgia is a common breast condition among women referred to breast clinics worldwide. Whereas the prevalence is known in the Western world and Asia, the prevalence of the disease is unknown in many African countries. The aim of this study therefore was to determine the prevalence and describe factors associated with mastalgia among women attending a tertiary hospital in sub-Saharan Africa. |i|Methods|/i|. A cross-sectional study was done in Kampala, Uganda. Mastalgia was defined as self-reported breast pain (unilateral or bilateral) for a period not less than two months. A pretested questionnaire was used to collect the data and statistical analysis was performed using SPSS version 11. Ethical approval was obtained. |i|Results|/i|. Out of the 1048 women who presented to the breast clinic during the study period, 168 (16%) were diagnosed with mastalgia in the absence of breast cancer. Noncyclical and cyclical mastalgia were 22/168 (13%) and 5/168 (3%), respectively. The onset of
Test is a risk assessment tool developed by Silbiotech, Inc for patients who have been diagnosed with Atypical and other hyperplasias.
Stay on top of the latest knowledge in the field with this must-have resource for all clinicians who treat breast diseases. Expand your knowledge of every aspect of breast diseases as a diverse and distinguished group of internationally-recognized experts summarize the current knowledge, including biology and epidemiology, clinical features, and management. Ideal for any clinician seeing patients with breast disease, especially carcinoma of the breast, This full color 5th Edition of the authoritative text in the field is designed to foster the understanding necessary to provide optimal patient care.. Features ?Covering the latest major clinical trials, along with concise management summaries for each clinical chapter. Illustrations and tables that emphasize breast imaging, microscopic and gross histology, anatomy, and procedural technique enhance visual understanding. Algorithms on problem management in all aspects of breast disease from benign processes to breast carcinoma inform clinical ...
Melbourne International Breast Congress - joint with the Australasian Society for Breast Disease (ASBD), 4th World Congress on Controversies in Breast Cancer (CoBrCa) and Breast Surgeons of Australia, The collaboration will create a multi-faceted ...
Atypical hyperplasia is identified in 4% to 10% of benign breast biopsies (42-44). Recent data suggest that the absolute risk of future breast cancer imparted after a biopsy demonstrating atypia is about 30% at 25 years, comparable to the risk associated with mantle radiation prior to 31 years, a well-recognized indication for breast cancer risk reduction interventions (33, 45-47). While a prior benign breast biopsy showing atypia confers a substantial risk for the future development of breast cancer, currently used models to predict breast cancer risk are poorly applicable to these women, although a risk model incorporating benign breast biopsy histology recently has been published (48). In current practice, the use of cumulative incidence data is recommended when counseling women with atypical hyperplasia on their future risk of breast cancer and the number of atypical foci is reported as the best further discriminant of risk for these high-risk women (47). Despite these advances, further ...
The authors note that caffeine - found in coffee, chocolate, tea, soft drinks, and various medications - is thought to be the worlds most commonly ingested drug.. That said, recent research focused on women diagnosed with non-cancerous breast disease revealed that cutting caffeine from the diet could improve symptoms among such patients.. Because benign breast disease is considered to be a risk factor for developing the malignant form of the disease, this finding had raised concerns that caffeine might also elevate the risk for breast cancer.. To explore this possibility, Dr. Zhang looked at the diets of almost 39,000 women over the age of 45 over a period of four years, between 1992 and 1995.. All the women were part of The Womens Health Study, a cohort of US health professionals, and 75 percent were registered nurses.. All the women worked as health-care professionals - three-quarters as registered nurses.. The research team observed that nearly one-quarter never drank coffee, and about ...
Aim: To investigate the role of diffusion weighted magnetic resonance imaging (MRI) in differentiation of benign and malignant breast lesions using apparent diffusion coefficient (ADC) values preoperatively.. Methods: A total of 30 women between the ages of 14-75 years (mean, 47, 6 years) with 30 histopathologically verified breast lesions were investigated in this study. The patients were examined by a 1, 5 T MRI device using bilateral phased array breast coil. Spin echo planar diffusion imaging was used to scan patients. Images were obtained by b values 0 and 500 seconds/mm². Mean ADC values of the benign and malignant lesions were measured and calculated. The comparison between the histopathological diagnoses and the mean ADCs were performed by Mann Whitney U test.. Results: The diagnosis of 30 patients with 30 breast lesions were as follows; malign lesions (n=13), benign lesions (n=17). The ADC values were as follows (in units of 10-3mm² /sec): benign breast lesions (range: 1, 09-1, 98, ...
Breast cancer affects 1 in 10 women and the majority of UK women will attend a breast clinic at least once during their lives. The patients journey through assessment and management is one that involves a huge range of healthcare professionals, in which the truly multidisciplinary management style required has previously been only sparsely addressed. This resource provides a practical guide on how to investigate and manage common breast problems for all members of the breast disease team, and covers the whole of the patient journey from assessment through to surgery and adjuvant treatments, giving a practical overview of the whole process of care. It includes the latest evidence, guidance and references on breast disease, together with discussions on current controversies in the field including the management of margins, management of the axilla and the evidence surrounding the NHS Breast Screening Programme. To give practical advice on the realities of being part of a breast care team, this ...
Breast cancer affects 1 in 10 women and the majority of UK women will attend a breast clinic at least once during their lives. The patients journey through assessment and management is one that involves a huge range of healthcare professionals, in which the truly multidisciplinary management style required has previously been only sparsely addressed. This resource provides a practical guide on how to investigate and manage common breast problems for all members of the breast disease team, and covers the whole of the patient journey from assessment through to surgery and adjuvant treatments, giving a practical overview of the whole process of care. It includes the latest evidence, guidance and references on breast disease, together with discussions on current controversies in the field including the management of margins, management of the axilla and the evidence surrounding the NHS Breast Screening Programme. To give practical advice on the realities of being part of a breast care team, this ...
A research team at M.D. Anderson Cancer Center in Houston, TX, is investigating whether the amount of DNA damage seen in the cells in normal breast tissue may be an indicator of future breast cancer risk. The researchers recruited women who had a benign breast biopsy and then went on to develop breast cancer (Phase I) and women who had a benign breast biopsy but did NOT go on to develop breast cancer (Phase II). By recruiting women who did develop breast cancer and women who did not, they will be able to look for markers in the breast cells that might be an indicator of breast cancer risk. The researchers wanted to enroll at least 150 women in the study. The Call to Action for Phase I was sent to Army of Women members on August 11, 2010, while the Call to Action for Phase II was sent on January 18, 2012. When the research team closed enrollment on July 10, 2013, the Army of Women had provided them with 338 women who were interested in enrolling in Phase I and 1,333 women who were interested in ...
TY - JOUR. T1 - Automated classification of focal breast lesions according to S-detect: validation and role as a clinical and teaching tool. AU - Bartolotta, Tommaso Vincenzo. AU - De Vito, Corrado. AU - DAmbrosio, Ferdinando. AU - Migliara, Giuseppe. AU - Di Segni, Mattia. AU - Magri, Valentina. AU - Rubini, Antonello. AU - De Soccio, Valeria. AU - Bonito, Giacomo. AU - Di Segni, Gabriele. AU - Lamorte, Sveva. AU - De Felice, Carlo. AU - Metere, Alessio. AU - Cantisani, Vito. AU - Giacomelli, Laura. AU - De Felice, Carlo. AU - De Felice, Carlo. PY - 2018. Y1 - 2018. N2 - AbstractPURPOSE:To assess the diagnostic performance and the potential as a teaching tool of S-detect in the assessment of focal breast lesions.METHODS:61 patients (age 21-84 years) with benign breast lesions in follow-up or candidate to pathological sampling or with suspicious lesions candidate to biopsy were enrolled. The study was based on a prospective and on a retrospective phase. In the prospective phase, after ...
Pain between breasts - MedHelps Pain between breasts Center for Information, Symptoms, Resources, Treatments and Tools for Pain between breasts. Find Pain between breasts information, treatments for Pain between breasts and Pain between breasts symptoms.
Purple spots on my breast symptoms - Hi Ive found two purple spots on top of my breast and I dont know what they are (i am female)? See your doctor. If the spots are away from the nipple it could be anything like a bruise or bite or insect bite. If they are close to the nipple they can be inflamed montgomery glands (they lubricate the nipple). Go see your doc if it does not spontaneously go away. Do you have nipple discharge? If bloody always go see your doc.
This is a forum where you can post a particular breast pathology question for Dr. Lawton and read other participants questions and Dr. Lawtons answers.. ...
TY - JOUR. T1 - Life after breast cancer.. AU - Stuart, Kirsty. AU - Brennan, Meagan. AU - French, James. AU - Houssami, Nehmat. AU - Boyages, John. PY - 2006/4. Y1 - 2006/4. N2 - This thirteenth article in our series on breast disease explores the many concerns that patients face after completion of their breast cancer treatment. The diagnosis and treatment of breast cancer is an ordeal for women on a number of levels. Similarly, there are often a multitude of issues and concerns raised after the completion of treatment. Having an awareness of these medical and survivorship issues allows the general practitioner to provide important support to both the patient and her family.. AB - This thirteenth article in our series on breast disease explores the many concerns that patients face after completion of their breast cancer treatment. The diagnosis and treatment of breast cancer is an ordeal for women on a number of levels. Similarly, there are often a multitude of issues and concerns raised after ...
Legenda: riscontro frequente *, intermedio **, raro ***. BIBLIOGRAFIA/LETTURE CONSIGLIATE. 1- L.E. Hughes, R.E.Mansel, D.J.T. Webster: Benign disorders and diseases of the breastBaillère Tindall Ed.: 1989. 2 - Thomas D.B.: Role of exogenous female hormones in altering the risk of benign and malignant neoplasms in human.. Cancer Research 1989; 38:3991-4000.. 3- Berkowitz G.S., Canny P.F., Vivolsi V.A. & Al.: Cigarette smoking and benign breast disease. Journal of epidemiology. and community health 1985; 39:308-131.. 4- Foster M.E.,Garrahan N. & Williams S.: Fibroadenoma of the breast - a clinical and pathological study. Journal of the. Royal College of Surgeons ( Edimbourgh) 1987.. 5- Haagensen C.D.: Diseases of the breast, 3rd Ed Philadelphia, W.B Saunders 1986.. 6- Hughes L.E, Mansell R.E, Webster D.J.: Fibroadenoma and related tumors p 59-73 - Cancer in a fibroadenoma p 65 - in. Benign disorders and Diseases of hte Breast: Concepts and Clinical Management; Baillière Tindall 1989.. 7-- Hertel ...
Hyperplasia is also known as proliferative breast disease. Its an overgrowth of the cells that line the ducts or the milk glands. Learn more.
We usually recommend doing it after each period, or once a month if you are beyond the menopause. First you look at yourself in good light in front of a mirror. Look for dimpling, puckering, or redness of the breast. Then lie flat on your back and using your sensitive fingertips search one breast and then the other. If you think you have found a lump, you compare it with the same area on the opposite side, the mirror-image of it. If you can find something there that is similar, it may turn out to be normal tissue. You also look for a dominant lump, or one that is larger than the other normal-sized lumps, and you look for a lack of symmetry from side to side.. Breast problems are evaluated by physical exam, and by testing that includes breast ultrasound, mammography and MRI. We perform a clinical breast exam in our office at least once a year. We check for changes in size or shape, we look for dimples or redness of the skin. We feel for lumps that are larger than they should be, and we ...
Aberrations in the Normal Development and Involution of the breast (ANDI) is an all-encompassing term that is used to describe a wide spectrum of the benign breast diseases. As the name suggests, it is based on the theory that most of the encount...
Background Females with atypical hyperplasia (AH) on a benign breast biopsy (BBB) are at increased risk for the development of breast cancer. not significantly contribute to breast cancer risk. The lack of a significant dose-response relationship between extent and type of atypia and breast cancer risk suggests that it would be premature to use extent of atypia to influence management decisions in women with ADH or ALH. and extent of atypia, it became apparent that association between extent of atypia and breast cancer risk was being driven by type of atypia, i.e. ALH, rather than extent of atypia (Table 3). Hartmann and colleagues have reported that the extent of atypia is significantly related to 97207-47-1 manufacture the subsequent breast cancer risk with relative risks of 3.2, 5.5 and 7.6 for 1, 2 and 97207-47-1 manufacture 3+ foci of atypical hyperplasia 97207-47-1 manufacture ( ...
Power3 Medical Products, Inc. (Houston) is a clinical diagnostics company commercializing powerful proteomics methods for diagnosing a range of serious human illnesses. Among its development-stage tests are diagnostics for cancer, neurologic diseases, and cancer drug resistance. In developing its breast cancer diagnostic, Power3 used 2-D gel electrophoresis to quantify differentially expressed protein biomarkers related to that disease from a group of 39 breast cancer patients and 38 controls with benign breast disease. The result was a proteomic profile of the serum and a statistical model that differentiates breast cancer patients from control subjects.. From thousands of expressed proteins, researchers identified a panel of 22 protein biomarkers whose expression differs significantly between the test groups. These proteins were selected by image analysis and identified using high performance liquid chromatography and mass spectrometry.. No single biomarker among these 22 possessed any ...
Breast cancer affects 1 in 10 women and the majority of UK women will attend a breast clinic at least once during their lives. The patients journey through assessment and management is one that involves a huge range of healthcare professionals, in which the truly multidisciplinary management style required has previously been only sparsely addressed.
A breast lump may either be a cyst filled with fluid or a solid mass of tissue. A sample of the breast tissue (biopsy) must be made to determine whether malignant (cancerous) cells are present. Almost two-thirds of all breast lumps are benign but the chance of a malignant lump is greatly increased if the woman is past menopause.. While the patient is awake and pain-free (using local anesthesia) or asleep and pain-free (using general anesthesia), an incision is made over the lump. The incision for a lumpectomy is usually around 3 to 4 centimeters long. The incision will also depend on the size of the lump that needs to be removed. After the lump is removed in one piece, it is sent to the laboratory for immediate examination. If the lump is found to be cancerous nearby lymph nodes will be removed to check for the extent of the cancer spreading.. ...
Breast lumps or changes are a common health worry for most women. Women may have many kinds of breast lumps and other breast changes throughout their lives, including changes that occur with menstrual periods, pregnancy, and aging. Most breast lumps and breast changes are normal. Breast changes in young girls Breast...
The study included 8736 women who biopsies at the Mayo Clinic benign benign during a 25 - year period from 1967, Breast tissue samples from this Mayo Clinic Benign Breast Disease cohort were evaluated the extent the extent of the recovery. As a group, the Mayo cohort http://www.levitra-danmark.net/vardenafil-hvad-er-det.html . Increased at 40 % risk …. ...
REX Breast Care Specialists offers education, discussion, counseling, and individualized treatment planning to women with benign, suspicious, and malignant breast diseases.
Kevin Wasco specializes in General Surgery and practices primarily at Surgical Associates of Neenah SC in Neenah, Wisconsin. Special interests include: Abdominal Cancer Surgery, Abdominal Surgery, Appendectomy, Bariatric Surgery, Benign Breast Disease,.
Pseudoangiomatous stromal hyperplasia is a rare benign breast neoplasm. The exact prevalence of this condition is unknown. According to the literature, it is an extremely uncommon disease in adolescent patients, especially when presenting with a giant mass causing significant breast enlargement. The clinical management of pseudoangiomatous stromal hyperplasia continues to be a controversial issue, however, surgical treatment remains the most accepted when there is an important mass-effect. We report the case of a 12-year-old premenarchal female, referred to our hospital with complaints of a rapidly enlarging left breast mass, of 12cm in diameter, causing a significant breast asymmetry. The ultrasonographic findings were unspecific. The core needle biopsy of the mass was consistent with pseudoangiomatous stromal hyperplasia, consequently, successful surgical excision was performed. This case illustrates a particularly unusual presentation of pseudoangiomatous stromal hyperplasia in a premenarchal
Hamartomas of the breast, also known as fibroadenolipomas, lipofibroadenomas or adenolipomas, are benign lesions. Hamartomas account for between 0.04 and 1.15% of all benign breast tumors in females. Myoid hamartoma of the breast (MHB) is extremely rare. The present study describes a case of MHB in a 44-year-old female. Screening mammography revealed a lobulated partial indistinct isodense mass measuring ~3.8 cm in the upper outer quadrant of the left breast. Sonographic examinations revealed a 2-3-cm mass in the left breast, which was fairly well circumbscribed and demonstrated complex scattered echogenic areas and isoechoic tissue. A core needle biopsy demonstrated fibrocystic changes, with small focal ductule aggregations. As malignancy could not be excluded, a partial mastectomy was performed using a circumareolar incision. The mass was histopathologically diagnosed as MHB with focal chondromyoxid metaplasia and pseudoangiomatous stromal hyperplasia. The histological diagnosis was based upon ...
Here we present a case of an 11-year old hispanic girl affected by bilateral mammary nodular pseudoangiomatous stromal hyperplasia, an uncommon breast disease, with a review of the literature related to diagnostic workup, differential diagnosis, and management. A rapidly growing mass in the breast may be stressful for both parents and child as the suspicion of malignancy arises. Multiple wide excisions of both breasts were performed.. CONCLUSIONS ...
TY - JOUR. T1 - Molecular breast imaging in pseudoangiomatous stromal hyperplasia. AU - Boughey, Judy C.. AU - Tortorelli, Cindy. AU - Hruska, Carrie. AU - OConnor, Michael. AU - Rhodes, Deborah. PY - 2010/7/1. Y1 - 2010/7/1. UR - http://www.scopus.com/inward/record.url?scp=79959523332&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=79959523332&partnerID=8YFLogxK. M3 - Article. AN - SCOPUS:79959523332. VL - 1. JO - Journal of Surgical Radiology. JF - Journal of Surgical Radiology. SN - 2156-213X. IS - 1. ER - ...
Three cases are presented of complications after bilateral subcutaneous mastectomy with immediate prosthetic replacement, performed for benign breast disease in women who ranged in age from 24 to 32 years, by surgeons outside the field of plastic surgery.
Apologies for the hodge-podge of links presented here. This is from an e-mail communication... basically this is info that I feel important for anyone with FBD, also anyone with a diagnosis of ductal carcinoma in situ. IN SITU means in place . The cancer is in place. It is NOT spreading. I have become complacent. My fibrocystic breast disease is just a memory now. I need to keep posting this stuff because every day I hear of another woman that thinks that: A: fibrocystic breast disease is benign . B: A diagnosis of DCIS is life-threatening. FBD and DCIS are both manifestati ...
Benign (non-cancerous) diseases of the breast are common throughout a womans life. All new breast symptoms require a full assessment and often a biopsy is required to confirm the diagnosis. Probably the most worrying symptom is a breast lump and the cause of a benign lump often depends on the age of the woman. Young women are susceptible to a type of lump called a fibroadenoma often seen in the late teens/ early twenties. They are made up of a combination of connective tissue and active breast tissue (epithelium) and are completely benign. They can be removed or left alone once diagnosed.. Very rarely, the lump is a phyllodes tumour in which the connective tissue is found to be abnormal. The majority of phyllodes tumours are benign but they can be borderline or completely malignant. Phyllodes tumours are usually found in older women and tend to grow rapidly and need to be removed with a cuff of normal tissue to reduce the risk of them returning. Women who have phyllodes tumours removed are seen ...
TY - JOUR. T1 - Acidophilic nuclear inclusions are specific for florid ductal hyperplasia among proliferative breast lesions. AU - Lauer, Scott. AU - Oprea-Ilies, Gabriela. AU - Cohen, Cynthia. AU - Adsay, Volkan. AU - Adams, Amy L.. PY - 2011/6/1. Y1 - 2011/6/1. N2 - Context.-Recently we have observed distinctive acidophilic intranuclear inclusions in cases of usual intraductal hyperplasia of the breast. Similar inclusions were described almost 20 years ago in cases of mammary hyperplasia. These correlated ultrastructurally with so-called helioid inclusions. However, there since has been little discussion of these inclusions in the literature. Objective.-To examine the incidence and specificity of these inclusions in proliferative lesions of the breast. Design.-Forty cases of usual intraductal hyperplasia, 15 cases of atypical ductal hyperplasia, and 34 cases of lowgrade ductal carcinoma in situ were examined for the presence of acidophilic intranuclear inclusions. Results.-Acidophilic ...
Home » Breast lump. Breast lump (Science: oncology, surgery) a breast lump that may be benign or cancerous. Examples of breast lumps include: breast abscess, fat necrosis, fibroadenoma, fibrocystic breast disease and breast cancer. A breast biopsy is the best way to determine the aetiology of a breast lump. Remember, 80 to 85% of all biopsies are benign. ...
CYP19A1 encodes for aromatase, which irreversibly converts androgens to estrogens; variation in this gene may affect individual susceptibility to breast cancer and other sex hormone-dependent outcomes. In a case-control study nested within a breast self-examination trial conducted in China, we examined whether CYP19A1 polymorphisms (rs1870049, rs1004982, rs28566535, rs936306, rs11636639, rs767199, rs4775936, rs11575899, rs10046, and rs4646) were associated with risk of breast cancer and fibrocystic breast conditions. Cases were diagnosed with breast cancer (n = 614) or fibrocystic breast conditions (n = 465) during 1989 to 2000. Controls were free of breast disease during the same period (n = 879). Presence of proliferative changes within the extratumoral tissue of women with breast cancer and the lesions of women with fibrocystic conditions only was assessed. None of the polymorphisms were associated with overall risk of breast cancer or fibrocystic breast conditions. Differences in breast ...
Also called fibrocystic condition, fibrocystic change or cystic mastitis, fibrocystic breast disease is more a characteristic of the breast than a disease. It is often more prominent during ovulation
Fibrocystic breast disease. It really isnt a disease at all. It is not related to breast cancer in any way. Feeling a lump can be very scary and concerning. You need to seek the advice of a physician. It may not be breast cancer; it could be a Fibrocystic Breast Condition.
Learn more about Cyclic Mastalgia at Medical Center of Aurora Related Terms Breast Pain, Cyclic Breast Tenderness, Cyclic Cyclic Mastitis Fibrocystic Breast Disease Uses Principal...
Learn more about Cyclic Mastalgia at Sky Ridge Medical Center Related Terms Breast Pain, Cyclic Breast Tenderness, Cyclic Cyclic Mastitis Fibrocystic Breast Disease Uses Principal...
Learn more about Cyclic Mastalgia at Sky Ridge Medical Center Related Terms Breast Pain, Cyclic Breast Tenderness, Cyclic Cyclic Mastitis Fibrocystic Breast Disease Uses Principal...
Widespread use of mammography ends up in detection of small cancers with favorable diagnosis, in addition to an array of indeterminate lesions, nearly all of which develop into histologically benign. This publication offers an in depth account of the radiology and pathology of screening-detected lesions, with dialogue of hazard evaluate, to aid clinicians within the follow-up of their patients. comparable lesions are handled in consecutive chapters, giving the reader a chance for comparability. The e-book is definitely illustrated with radiological and pathological correlation of typically screening-detected photos together with mucocele-like lesions and columnar lesions. All professionals who care for sufferers with breast affliction, comparable to breast surgeons, radiologists, pathologists and breast care nurses, will locate the ebook highly useful for the management of sufferers with benign or indeterminate breast lesions in a multidisciplinary setting. ...
Fibrocystic breast disease diagnostics (costs for program #140161) ✔ University Hospital Münster ✔ Breast Center ✔ BookingHealth.com
The most common type of breast pain is associated with the menstrual cycle and is nearly always hormonal. Some women begin to have pain around the time of ovulation which continues until the beginning of their menstrual cycle. The pain can either be barely noticeable or so severe that the woman cannot wear tight-fitting clothing or tolerate close contact of any kind. The pain may be felt in only one breast or may be felt as a radiating sensation in the under-arm region.. Some physicians have women chart their breast pain to determine if the pain is cyclical or not. After a few months, the relationship between the menstrual cycle and breast pain will emerge.. Physicians continue to study the role that hormones play in cyclical mastalgia. One study has suggested that some women with cyclical mastalgia have a decreased ratio of progesterone to estrogen in the second half of the menstrual cycle. Other studies have found that an abnormality in the hormone prolactin may affect breast pain. Hormones ...
Fibrocystic Breast Disease. Mammalogy: Diagnostic in Sion, Switzerland ✈. Prices on BookingHealth.com - booking treatment online!
I have Fibrocystic breast disease and went to my GP with this problem , but also saying how my joints ached and felt very exhausted. Bloods done saying I was Borderline Hypothyroid and to recheck in...
Results from a continuing clinical trial in benign breast disease indicate that danazol may induce progesterone receptors and that this effect persists after treatment. In women given danazol the number of biopsy specimens that were positive for progesterone receptors rose from 14 out of 31 before treatment to 23 out of 30 at the end of six months treatment and remained raised at 21 out of 31 six months later. The number of biopsy specimens that were positive for oestrogen receptors rose transiently from eight out of 31 to 12 out of 30 and then fell to six out of 31. A satisfactory clinical response was achieved in 26 of the 31 patients but was maintained in only 11 six months or more after the end of treatment. It was only in this group that a significant and long-standing increase in progesterone receptors was observed. These findings suggest that in some women with benign breast disease who have been treated with danazol changes occur that may have long term benefit. ...
Diagnosing Benign Breast Conditions How are benign breast conditions and infections diagnosed? In addition to obtaining a complete medical history, your physician, in diagnosing a breast condition, may proceed with the following: Perform a complete physical examination to: locate any lump and feel its characteristics (i.e., texture, size, and relationship to the skin and chest muscles). look for changes in the nipples or the skin of the breast. check lymph nodes under the arm and above the collarbones. ...
Fibrocystic breast disease or fibroadenosis is a non-cancerous breast condition. Causes of fibrocystic breast disease or fibroadenosis include breast pain, breast lump, breast swelling.
You are here:Home/Research/ Byzantine Studies/ Resources for Scholars/ Bibliography on Gender in Byzantium/ Saints, Drugs and Surgery: Byzantine Therapeutics for Breast Diseases ...
PT is a rare disease that is classified into benign, borderline, and high grade malignant tumors. The distinction among these three subgroups is based on the combination of histological characteristics of the tumors and also it is predictive of the probable clinical course (4).. The epithelial component of PT may show changes ranging from hyperplasia to invasive carcinoma. Sawyer et al. showed hyperplasia in the epithelial component of PT in 60%, and a moderate to strong overexpression of cyclin D1 in 46% of cases (5). Cyclin D1 is frequently overexpressed in breast cancer and DCIS (6, 7) but not in atypical ductal hyperplasia and other benign breast diseases. So it was unexpected to find such expression in the epithelium of benign tumors (8, 9).. As it was mentioned before, the median age of occurrence of phyllodes tumor is 40 - 50 years, and also ductal carcinoma in situ arising in phyllodes tumor is a rare situation, so our patient aged 26 years old was one of the youngest cases of benign PT ...
A research team at M.D. Anderson Cancer Center in Houston, TX, is investigating whether the amount of DNA damage seen in the cells in normal breast tissue may be an indicator of future breast cancer risk. The researchers recruited women who had a benign breast biopsy and then went on to develop breast cancer (Phase I) and women who had a benign breast biopsy but did NOT go on to develop breast cancer (Phase II). By recruiting women who did develop breast cancer and women who did not, they will be able to look for markers in the breast cells that might be an indicator of breast cancer risk. The researchers wanted to enroll at least 150 women in the study. The Call to Action for Phase I was sent to Army of Women members on August 11, 2010, while the Call to Action for Phase II was sent on January 18, 2012. When the research team closed enrollment on July 10, 2013, the Army of Women had provided them with 338 women who were interested in enrolling in Phase I and 1,333 women who were interested in ...
Background: More than half of women present nipple discharge during reproductive age. Case: This case is about a 36 years old woman with unilateral spontaneous hyaline nipple discharge associated with breast pain. The study of scintimammography was compatible with multifocal proliferative lesion in situ. It was performed cytological smear of nipple discharge. It was paucicellular smear represented by cluster of ductal cells in three-dimensional design with hyperchromatic nuclei in the presence of myoepithelial cells. Red cells and signs of necrosis were not observed. The diagnosis of in situ ductal carcinoma was confirmed in biopsy and mastectomy specimen through the expression of calponin in myoepithelial cells at immunohistochemistry. It is known that the cytological examination of nipple discharge has low sensitivity and specificity. However, it is an easy and inexpensive procedure. Suspicious or positive results, may be important for guidance workup of patients in order to perform earlier ...
Central duct excision (also: major duct excision or Hadfields procedure) is the surgical removal (excision) of all lactiferous duct under the nipple. The excision of a single duct is called microdochectomy, a mere incision of a mammary duct (without excision) is microdochotomy. Central duct excision is a standard treatment of in case there is nipple discharge which stems from multiple ducts or cannot be traced back to a single duct. It is also indicated if there is bloody nipple discharge in patients beyond childbearing age. Duct excision may be indicated for the treatment of recurrent breast abscess and mastitis, and the total removal of all ducts from behind the nipple has been recommended to avoid further recurrence. In particular if the patient wishes to preserve breastfeeding ability, the condition of the mammary duct system is investigated by means of galactography (ductography) or ductoscopy in order to determine whether the excision of a single duct (microdochectomy) would be ...
Breast Conditions Potential breast conditions in young women: A young woman may experience a number of changes in her breasts during puberty and adolescence as she becomes an adult. Some breast changes or conditions are related to her menstrual cycle, while others may occur at any time. While most breast conditions are benign (non-cancerous), it is important for young women to be aware of proper breast health, so that they may detect any problems. Some of the breast conditions young women may experience...
2. Claus EB, Risch N, Thompson WD. Autosomal dominant inheritance of early-onset breast cancer. Implications for risk prediction. Cancer. 19947364351. 3. The palpable breast lump: information and recommendations to assist decision-making when a breast lump is detected. The Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer. Canadian Association of Radiation Oncologists. CMAJ. 1998;158:(suppl 3):S3-8. 4. Diagnosis and management of specific breast abnormalities. Rockville, Md.: Agency for Healthcare Research and Quality, Dept. of Health and Human Services, 2001; evidence report/technology assessment, 1530-4396, no. 33; AHRQ publication no. 01-E 046.. 5. Barton MB, Elmore JG, Fletcher SW. Breast symptoms among women enrolled in a health maintenance organization: frequency, evaluation and outcome. Ann Intern Med. 1999;130:651-7. 6. Liberman L, Abramson AF, Squires FB, Glassman JR, Morris EA, Dershaw DD. The Breast Imaging Reporting and Data System: ...
Summary: Purpose: to improve the diagnosis of relapse and metastasis of breast cancer in the postoperative period. Material and methods. 123 women were examined. Of these, 30 practically healthy women made up a control group, 20 women had benign breast diseases, 73 had breast cancer. The patients with ВС before the surgical intervention were divided into groups according to the stage of the disease. The 1st group consisted of 30 practically healthy women. In the second group - 20 women with fibroadenomas of the breast. In the third group - 33 women with l-ll stages of breast cancer without regional metastases. The 4th group consisted of 22 women with stage II breast cancer with regional metastases, in the 5th group - 18 patients with stage III breast cancer. After surgery, 68 patients were re-examined and divided into 2 analytical groups. The 6th group included women without clinical manifestations of relapses and metastases in the postoperative period - 44 (64.7%). Group 7 consisted of 24 ...
This refers to pain in the breast area that is unrelated to the menstrual cycle. Non-cyclical mastalgia may arise from the breast tissue itself, the underlying ribs, or from conditions such as hiatus hernia and angina. Although non-cyclical breast pain is not usually a symptom of cancer, occasionally, cancer has been detected in women with breast pain, especially if they are over 40 years old. Consequently, if you have non-cyclical mastalgia, it is important to consult your doctor.. Women with non-cyclical breast pain affecting one breast will require breast examination and they should also have a mammogram if they are over 35 years old. Treatment will depend upon the cause of the pain. Inflammation in the ribs can be treated with simple painkillers, such as ibuprofen (tablet or gel), whereas other conditions, such as angina or hiatus hernia, will require specialist treatment.. The general treatment for non-cyclical mastalgia is listed below:. ...
A new breast cancer risk-prediction model combining histologic features of biopsied breast tissue from women with benign breast disease and individual patient demographic information more accurately classified breast cancer risk than the current screening standard. Results of a Mayo Clinic study comparing the new model with the current standard, the Breast Cancer Risk Assessment Tool (BCRAT), are published in the Journal of Clinical Oncology. Study author, Amy C. Degnim, M.D., comments.. ...
A new breast cancer risk model that combines histologic features of biopsied breast tissue from women with benign breast disease and individual patient demographic information more accurately classified breast cancer risk.
Breast intraepithelial neoplasia is a term for a group of noninvasive conditions in which abnormal cells are found in the breast, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS), and atypical ductal hyperplasia (ADH), said Andrea De Censi, MD, director of the medical oncology unit at the National Hospital E.O. Ospedali Galliera - S.C. Oncologia Medica in Genoa, Italy. These conditions significantly increase a womans risk for invasive breast cancer. Because they are often driven by the hormone estrogen, treatment commonly includes five years of tamoxifen, given at 20 mg per day, after surgery and, if needed, radiotherapy ...
Breast pain, or mastalgia, is a common problem, accounting for at least 50% of breast problems presenting in general practice and 14% of referrals to an Australian breast clinic.1 As stated in the beginning, many women suffer breast pain so severe that it affects their lifestyles, marriages and sexual relationships, and even prevents them from hugging their children. If no obvious physical cause is found, the problem is all too often dismissed, without appropriate empathy and reassurance, as a normal physiological effect. However, its aetiology is not clear. ...
The material presented will be of practical relevance to general surgical pathologists, pathologists with particular interest in breast pathology, and pathology trainees. A case-based format will be utilized and cases will serve as springboards for discussion. Attendees will be provided with case histories and images or virtual slides prior to the course. Upon completion of this educational activity, participants should be able to:. ...
The Breast Pathology Fellowship is a Texas Medical Board-approved program offered by the Department of Pathology at UT Southwestern Medical Center.
În urma intraductal papilloma pathology examinări anatomopatologice amănunţite, prin imunohistochimie, diagnosticul final a fost de papilom intraductal cu arii de hiperplazie atipică şi carcinom in situ. Ductal® este amplasat aproape de sine și este cel mai potrivit pentru elemente prefabricate sau lucrări de reparații sau upgrade in-situ.
A mammogram is a procedure that uses low-dose x-rays to image breasts. Mammograms are used to aid in the early detection and diagnosis of breast diseases in women and men. Mammograms are used as a screening tool to detect early breast cancer in women experiencing no symptoms and to detect and diagnose breast disease in women experiencing symptoms such as a lump, pain or nipple discharge. Mammograms are performed by Medical Radiation Technologists with specific training in mammography. The Ontario Breast Screening Program (OBSP) is offered at all Trillium Health Partners locations.. ...
Researchers at Kaiser Permanente have found that patients with a very early form of breast cancer (ductal carcinoma in situ or DCIS) who have higher mammographic density may be at increased risk for subsequent breast cancer, ...
Summary: Purpose: to improve the diagnosis of relapse and metastasis of breast cancer in the postoperative period. Material and methods. 123 women were examined. Of these, 30 practically healthy women made up a control group, 20 women had benign breast diseases, 73 had breast cancer. The patients with ВС before the surgical intervention were divided into groups according to the stage of the disease. The 1st group consisted of 30 practically healthy women. In the second group - 20 women with fibroadenomas of the breast. In the third group - 33 women with l-ll stages of breast cancer without regional metastases. The 4th group consisted of 22 women with stage II breast cancer with regional metastases, in the 5th group - 18 patients with stage III breast cancer. After surgery, 68 patients were re-examined and divided into 2 analytical groups. The 6th group included women without clinical manifestations of relapses and metastases in the postoperative period - 44 (64.7%). Group 7 consisted of 24 ...
Breast cancer; Endometriosis; Female infertility (assisted reproduction); Prostate cancer; Uterine diseases (endometrial ... Thus they are commonly employed in the medical management of prostate cancer and have been used in patients with breast cancer. ... Breast cancer; Endometriosis; Menorrhagia; Precocious puberty; Prostate cancer; Uterine fibroids. Injection; Implant. 1985. ... Fertility medicine; Prostate cancer; Breast cancer; Menorrhagia; Endometriosis; Uterine fibroids; Hyperandrogenism; Hirsutism; ...
Sulik, Gayle (2010). Pink Ribbon Blues: How Breast Cancer Culture Undermines Women's Health. New York: Oxford University Press ... Acute disease. An acute disease is a short-lived disease, like the common cold.. Chronic disease. A chronic disease is one that ... hereditary diseases (including both genetic diseases and non-genetic hereditary diseases), and physiological diseases. Diseases ... Subclinical disease. Also called silent disease, silent stage, or asymptomatic disease. This is a stage in some diseases before ...
Sulik, Gayle (2010). Pink Ribbon Blues: How Breast Cancer Culture Undermines Women's Health. New York: Oxford University Press ... Acute disease. An acute disease is a short-lived disease, like the common cold.. Chronic disease. A chronic disease is one that ... It also sounds like it could imply secondary disease, but acquired disease can be primary disease.. Acute disease disease of a ... hereditary diseases (including both genetic diseases and non-genetic hereditary diseases), and physiological diseases. Diseases ...
California Breast Cancer Organizations (CABCO). *Celiac Disease Foundation. *Center for Science in the Public Interest ... CUE membership is currently about 50 member groups; the earliest members include the National Breast Cancer Coalition, Consumer ...
... breast cancer, venous thromboembolic disease, and osteoporosis.[14][23] In contrast to these potentially increased risks, rare ... The surgical removal of the breasts may be considered for both the psychological reasons and to reduce the risk of breast ... "Orphanet Journal of Rare Diseases. 1: 42. doi:10.1186/1750-1172-1-42. PMC 1634840. PMID 17062147.. ... "Orphanet Journal of Rare Diseases. 1: 42. doi:10.1186/1750-1172-1-42. PMC 1634840. PMID 17062147.. ...
no reduction in cardiovascular disease[38]. *no statistically significant reduction in invasive breast cancer[39] ... Lipids in Health and Disease. 9: 94. doi:10.1186/1476-511X-9-94. PMC 2941756 . PMID 20815907.. ... 2006). "Low-carbohydrate-diet score and the risk of coronary heart disease in women". N. Engl. J. Med. 355 (19): 1991-2002. doi ... Jennifer Petrelli; Kathleen Y. Wolin (2009). Obesity (Biographies of Disease). Westport, Conn: Greenwood. p. 11. ISBN 978-0-313 ...
Intercurrent diseases. Main article: Intercurrent disease in pregnancy. A pregnant woman may have intercurrent diseases, ... Missed periods, tender breasts, nausea and vomiting, hunger, frequent urination[1]. Complications. Miscarriage, high blood ... "Centers for Disease Control and Prevention. 21 August 2017. Archived from the original on 25 August 2017. Retrieved 25 August ... "Pregnancy complicated by disease". Merck Manual, Home Health Handbook. Merck Sharp & Dohme. Archived from the original on 10 ...
Breast diseaseEdit. In a number of breast pathologies, calcium is often deposited at sites of cell death or in association ... Pathologic basis of veterinary disease, fourth edition; Elsevier 2007.. *^ Robbins and Cotran (2009), Pathologic Basis of ... Laminated appearance suggests granulomatous disease while popcorn calcification indicates hamartoma. Malignant lesions may have ...
Straus MJ (1979). "New developments in the treatment of advanced lung cancer". The American Review of Respiratory Disease. 120 ... Straus MJ, Moran RE (1980). "The cell cycle kinetics of human breast cancer". Cancer. 46 (12): 2634-9. doi:10.1002/1097-0142( ... He subsequently took up posts at the Westchester County Medical Center as Chief of Neoplastic Diseases and the New York Medical ... and nodal status in human breast cancer". Cancer. 54 (8): 1586-90. doi:10.1002/1097-0142(19841015)54:8,1586::aid-cncr2820540820 ...
Webster's Benign Disorders and Diseases of the Breast. Elsevier Health Sciences. p. 312. ISBN 0-7020-2774-X. Trop I, Dugas A, ... Pre-operatively, also breast ultrasound and mammogram are performed to rule out other abnormalities of the breast. A ... Duct excision may be indicated for the treatment of recurrent breast abscess and mastitis, and the total removal of all ducts ... p. 1694 J Michael Dixon (22 June 2013). Breast Surgery: Companion to Specialist Surgical Practice. Elsevier Health Sciences. p ...
Szabo S, Haislip A, Garry R (2005). "Of mice, cats, and men: is human breast cancer a zoonosis?". Microsc Res Tech. 68 (3-4): ... News From an Old Disease". Veterinary Pathology. 48 (1): 98-116. doi:10.1177/0300985810390826. PMID 21149845.. ... There are many differences between mammary tumors in animals and breast cancer in humans, including tumor type, malignancy, and ... similarities to and differences from human breast cancer". J Proteome Res. 9 (12): 6380-91. doi:10.1021/pr100671c. PMID ...
As underweight children are more vulnerable to almost all infectious diseases, the indirect disease burden of malnutrition is ... Breast feeding and eating should resume as soon as possible.[42] Drinks such as soft drinks, fruit juices, or sweetened teas ... Overeating leads to many diseases, such as heart disease and diabetes, that may result in death. ... This conditions may include Crohn's disease or untreated coeliac disease.[4][9][52] Malnutrition may also occur due to ...
Breast Disease. 31 (1): 7-18. doi:10.3233/BD-2009-0290. PMC 3228251. PMID 20519801. Cancer Genome Atlas Research, Network. (4 ... Historically cancer was identified, understood, and treated as a monolithic disease. It was seen as a "foreign" component that ... in order to study the disease as a complex adaptive system with emerging properties at multiple biological scales. Cancer ... "Dynamic modelling of oestrogen signalling and cell fate in breast cancer cells". Nat. Rev. Cancer. 11 (7): 523-532. doi:10.1038 ...
Brinker, Nancy; Braun, Susan (1998-12-01). "The Susan G. Komen Breast Cancer Foundation1". Breast Disease. 10 (5-6): 23-28. doi ... Lisa A. Carey is a Distinguished Professor in Breast Cancer Research at UNC School of Medicine, Division Chief of Hematology ... and was named co-chair of the Alliance National Cooperative Group Breast Committee in 2016. In 1998, Carey was hired as a ... was named co-chair of the Alliance National Cooperative Group Breast Committee in 2016. In 2018, Carey was selected to serve on ...
Breast Disease. 11: 113-24. doi:10.3233/bd-1999-11110. PMID 15687597. Joyce JA, Fearon DT (April 2015). "T cell exclusion, ... Alzheimer's disease (AD) is a multi-faceted, age-dependent, progressive neurodegenerative disorder, and is a major cause of ... "A Study to Confirm Safety and Efficacy of BAN2401 in Participants With Early Alzheimer's Disease". Case Medical Research. 2019- ... Monoclonal antibody therapy may prove to be beneficial for cancer, autoimmune diseases, and neurological disorders that result ...
The disease is characterised by the formation of painful abscesses in the mouth, lungs, breast, or gastrointestinal tract. ... Breast Disease. 35 (1): 45-47. doi:10.3233/BD-140381. PMID 25095985. Ryan KJ; Ray CG, eds. (2004). Sherris Medical Microbiology ... but the disease remained classified as a fungus in the 1955 edition of the Control of Communicable Diseases in Man. Violinist ... Disease incidence is greater in males between the ages of 20 and 60 years than in females. Before antibiotic treatments became ...
... from embryogenesis to breast cancer progression". Breast Disease. 29: 91-103. doi:10.3233/bd-2008-29110. PMC 3175751. PMID ... from embryogenesis to breast cancer progression". Breast Disease. 29: 91-103. doi:10.3233/BD-2008-29110. PMC 3175751. PMID ...
Center for Disease Control and Prevention (2013). "Strategies to Prevent Obesity and Other Chronic Diseases: The CDC Guide to ... Montgomery, D.L.; Splett, P.L. (1997). "Economic Benefit of Breast-Feeding Infants Enrolled in WIC". Journal of the American ... There are benefits for mothers too: women who don't breastfeed have increased risk of developing heart disease, hypertension, ... diabetes, high cholesterol, breast cancer, ovarian cancer and hip fractures in later life.[9][10][11] The BFHI aims to increase ...
In a living organism, this can have disastrous effects, often in the form of disease or disorder. A discussion of every disease ... "Saturated fatty acid-induced apoptosis in MDA-MB-231 breast cancer cells. A role for cardiolipin". The Journal of Biological ... The most common of these diseases is cancer, the disease of excessive cellular proliferation, which is often characterized by ... OROV is a disease that is transmitted between humans by the biting midge (Culicoides paraensis).[101] It is referred to as a ...
These drugs also cross the placenta and are secreted in breast milk. Lugol's iodine may be used to block hormone synthesis ... Begbie's disease, Flajani's disease, Flajani-Basedow syndrome, and Marsh's disease.[39] These names for the disease were ... a b c d e f g Basedow's syndrome or disease at Who Named It? - the history and naming of the disease ... Graves' disease[39][40] has also been called exophthalmic goiter.[40] Less commonly, it has been known as Parry's disease,[39][ ...
"Silicone Breast Implants in Relation to Connective Tissue Diseases and Immunologic Dysfunction". Archived from the original on ... "Coronary Heart Disease". Weitz & Luxenberg P.C. Archived from the original on May 30, 2013. Retrieved March 20, 2013.. ... Cardiovascular disease associated with COX-2 inhibitors (i.e. Vioxx)[15]. *Deafness and kidney failure associated with ... "Centers for Disease Control and Prevention (CDC). 2018-07-12. Archived from the original on March 17, 2017. Retrieved March 20, ...
In mammals, including humans, it occurs also via breast milk (transmammary transmission). Infectious diseases that can be ... See also: Mathematical modelling of infectious disease. Tracking the transmission of infectious diseases is called disease ... although all contagious diseases are infectious, not all infectious diseases are contagious). These diseases can also be ... Diseases that are known to be transmissible by kissing or by other direct or indirect oral contact include all of the diseases ...
... skinless chicken breast, the amount is much lower. A 100-g serving of baked chicken breast contains 4 g of fat and 31 g of ... Centers for Disease Control and Prevention. Retrieved March 3, 2014.. *^ "The evolution, and revolution, of flu vaccines". FDA ... Barn systems have been found to have the worst bird welfare.[44] In Southeast Asia, a lack of disease control in free-range ... Other birds with breast muscle more suitable for sustained flight, such as ducks and geese, have red muscle (and therefore dark ...
The guideline recommends "for serious skin, bone, and soft tissue M fortuitum disease, a minimum of 4 months of therapy with at ... Has produced postoperative infections after breast augmentation surgery. Biosafety level 2 The 2007 guideline "Official ... M. fortuitum infection can be a nosocomial (hospital acquired) disease. Surgical sites may become infected after the wound is ... Surgery is generally indicated with extensive disease, abscess formation, or where drug therapy is difficult." Found world-wide ...
Gentilini OD, Boccardo C (2015). "Male Breast Diseases". The Outpatient Breast Clinic: 431-446. doi:10.1007/978-3-319-15907-2_ ... and Tanner stage III/11 of the right and left breast in 1. The 7th patient was noted to have Tanner Ill breasts at her 2nd ... This included breast development to Tanner stage 2 and 3 in 86% of the patients after an average of 5.7 months of treatment, ... Some gynecomastia and breast tenderness developed in one patient treated with 50 mg/day, but significantly improved upon the ...
A common example of pleiotropy is the human disease phenylketonuria (PKU). This disease causes mental retardation and reduced ... These include breast milk, eggs, chicken, beef, pork, fish, nuts, and other foods. A special PKU formula can be obtained in ... "Complications and Treatments , Sickle Cell Disease". CDC. Retrieved 2016-11-11.. *^ a b c d "Marfan Syndrome". National ... "sickle cell disease". Genetics Home Reference. Retrieved 2016-11-11.. *^ MD, Kenneth R. Bridges. "How Does Sickle Cell Cause ...
Centers for Disease Control and Prevention. [2008-09-09].. *^ FDA Backgrounder on Platinum in Silicone Breast Implants. U.S. ... Platinum in silicone breast implants. Biomaterials. 2006, 27 (17): 3274-3286. PMID 16483647. doi:10.1016/j.biomaterials.2006.01 ...
Pittet, B; Montandon, D; Pittet, D (2005). "Infection in breast implants". The Lancet Infectious Diseases. 5 (2): 94-106. doi: ... 2003). "Noma: An "infectious" disease of unknown aetiology". The Lancet Infectious Diseases. 3 (7): 419-31. doi:10.1016/S1473- ... Melbourne Infectious Diseases Group (Australia) 2009: European Society of Clinical Microbiology and Infectious Diseases (ESCMID ... Noma, disease of poverty Pittet, B; Jaquinet, A; Montandon, D (2001). "Clinical experience in the treatment of noma sequelae". ...
Sen M, Gorpelioglu C, Bozer M (2009). "Isolated primary breast tuberculosis: report of three cases and review of the literature ... African Journal of Infectious Diseases. 5 (1): 7-10. doi:10.4314/ajid.v5i1.66508. PMC 3497843. PMID 23878702. Baharoon S (July ... These can affect any organ such as the brain, intestine, ovaries, breast, lungs, esophagus, liver,[citation needed] pancreas, ... importance of recognition and differentiation from that of a breast malignancy: report of three cases and review of the ...
eds.). Diagnosis of Diseases of the Breast. Philadelphia, Pennsylvania: Saunders. ISBN 978-0-7216-9563-1. OCLC 488959603. ... That year he published "A Roentgenologic Study of the Breast". X-ray imaging of the breast had first been investigated by ... He was even able to detect an undiagnosed cancer in a breast that had been removed because of a large cyst. However, Salomon ... Warren developed the technique of producing stereoscopic images of the breast with X-rays while working in the Department of ...
大多數的基因是存在細胞核中,但是細胞中一個稱為粒線體的胞器,也擁有自己的基因組。粒線體基因組在粒線體疾病(mitochondrial disease)中具有一定的重要性。而且這些基因也可以用來研究人類的演化,舉例而言,若分析人類粒線體基因組的變異情況,將 ... Inhibition of breast cancer growth and invasion by single-minded 2s.. Carcinogenesis. PMID 16840439.. ... Olson M, Varki A. Sequencing
"Physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: ... Diseases of the endocrine system (ICD-10 Chapter IV: Endocrine, nutritional and metabolic diseases - Endocrine diseases, E00- ... Diabetes was one of the first diseases described.[21] The importance of insulin in the disease was determined in the 1920s.[22] ... two to four times the risk of cardiovascular disease, including ischemic heart disease and stroke; a 20-fold increase in lower ...
... breast milk, urine and semen.[4][41] The WHO states that only people who are very sick are able to spread Ebola disease in ... "Ebola Virus Disease". SRHD. Retrieved 15 September 2020.. *^ a b c d "Q&A on Transmission, Ebola". Centers for Disease Control ... "About Ebola Virus Disease". Centers for Disease Control and Prevention (CDC). Archived from the original on 16 October 2014. ... "Ebola (Ebola Virus Disease) Transmission". Centers for Disease Control and Prevention (CDC). 5 November 2014. Archived from the ...
... through the End Stage Renal Disease Program) people of all ages with end-stage renal disease. The Medicare Program provides a ... A 2020 JAMA study found that Medicare expansion under the ACA was associated with reduced incidence of advanced-stage breast ... chronic obstructive pulmonary disease; and complications of devices, implants and grafts.[78] ... "Association of Medicaid Expansion Under the Affordable Care Act With Breast Cancer Stage at Diagnosis". JAMA Surgery. doi ...
... and IgG4-related disease.[27] There is some evidence that it is ineffective in treating IgA-mediated autoimmune diseases.[28] ... "Breast cancer research : BCR. 3 (2): 86-90. doi:10.1186/bcr276. PMC 138676. PMID 11250751.. ... Autoimmune diseases[edit]. Rituximab has been shown to be an effective rheumatoid arthritis treatment in three randomised ... Bosch, Xavier; Ramos-Casals, Manuel; Khamashta, Munther A. (2013). Drugs Targeting B-Cells in Autoimmune Diseases. Springer ...
Ischaemic Heart Disease (9.2%) 3. Lower respiratory infection (7%) 4. Diarrhoeal disease (3.3%) 5. Self harm (3%) 6. ... Nepal's Breast Milk Substitute Act (2049) of 1992 promotes and protects breastfeeding and regulates the unauthorized or ... Disease prevalence is higher in Nepal than it is in other South Asian countries, especially in rural areas. Moreover, the ... Traditional beliefs have also been shown to play a significant role in the spread of disease in Nepal. These problems have led ...
It is often described as being "a disease of the diseased", occurring in the very young, the very old, or the very sick. ... with the breast of the bird of the same name. Many pseudoscientific claims by proponents of alternative medicine surround the ... Candidiasis can be a marker for underlying disease, so the overall prognosis may also be dependent upon this. For example, a ... 2006). Andrews' Diseases of the Skin: Clinical Dermatology. Philadelphia: Saunders Elsevier. p. 308. ISBN 0-7216-2921-0. OCLC ...
SP concentrations cannot yet be used to diagnose disease clinically or gauge disease severity. It is not yet known whether ... "Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for bone marrow ... Microbial Toxins and Diarrhoeal Disease. Ciba Found. Symp. 112. pp. 139-54. doi:10.1002/9780470720936.ch8. PMID 2861068.. ... Quantification in diseaseEdit. Elevation of serum, plasma, or tissue SP and/or its receptor (NK1R) has been associated with ...
Breast cancer hypothesis[change , change source]. There is a hypothesis that induced abortion raises the risk of getting breast ... Those with certain diseases, and those over the age 35 also run a greater risk. Other causes for abortions can be the infection ... "Breast Cancer Risks". United States House Committee on Oversight and Government Reform. Retrieved 2008-04-14.. ... Certain diseases or an accidental trauma can also cause a spontaneous abortion. Putting the woman under trauma or stress to ...
... and IgG4-related disease.[27] There is some evidence that it is ineffective in treating IgA-mediated autoimmune diseases.[28] ... "Breast Cancer Research : BCR. 3 (2): 86-90. doi:10.1186/bcr276. PMC 138676. PMID 11250751.. ... "Annals of the Rheumatic Diseases. 62 (90002): 55ii-59. doi:10.1136/ard.62.suppl_2.ii55. PMC 1766758. PMID 14532151.. ... Autoimmune diseasesEdit. Rituximab has been shown to be an effective rheumatoid arthritis treatment in three randomised ...
Coccidians in the genus Aggregata living in the gut cause severe disease to the host. Octopuses have an innate immune system, ... and bare breasts.[131][132] ... The diseases and parasites that affect octopuses have been ...
Mandel SJ, Brent GA, Larsen PR (September 1993). "Levothyroxine therapy in patients with thyroid disease". Annals of Internal ... While a minimal amount of thyroid hormones are found in breast milk, the amount does not influence infant plasma thyroid levels ... For older people (over 50 years old) and people with known or suspected ischemic heart disease, levothyroxine therapy should ... Levothyroxine is also used as interventional therapy in people with nodular thyroid disease or thyroid cancer to suppress ...
By 1682, when William Penn arrived to his American commonwealth, the Lenape had been so reduced by disease, famine, and war ... was a favorite component of headdresses and breast ornaments for males.[32] The Lenape also adorned themselves with various ... as the diseases had arisen on the Asian continent and moved west into Europe, where they had become endemic in the cities. ... due to high fatalities from epidemics of infectious diseases carried by Europeans, such as measles and smallpox, to which they ...
... in patients with HER2-positive metastatic breast cancer progressing after trastuzumab". Breast Cancer Research and Treatment. ... Interstitial lung disease. Mechanism of action[edit]. Like lapatinib and neratinib, afatinib is a protein kinase inhibitor that ... "Breast Cancer Research and Treatment. 134 (3): 1149-59. doi:10.1007/s10549-012-2126-1. PMC 3409367. PMID 22763464.. ... Her2-negative breast cancers showed limited or no response to the drug.[18] ...
... and breast milk.[78] However, according to the CDC, live spirochetes have not been found in breast milk, urine, or semen and ... "Lyme disease rashes and look-alikes". Lyme Disease. Centers for Disease Control and Prevention. 21 December 2018. Archived from ... "Lyme Disease Data and surveillance". Lyme Disease. Centers for Disease Control and Prevention. 5 February 2019. Archived from ... Treatment regimens for Lyme disease range from 14 days in early localized disease, to 14-21 days in early disseminated disease ...
Significant diseases. Cancer, bone fractures. Significant tests. screening tests, X-ray, CT, MRI, PET, bone scan, ...
Colorectal Disease. 10 (8): 789-792. doi:10.1111/j.1463-1318.2007.01381.x. PMID 17868406.. ... which may be useful in case of fecal incontinence or neurologic diseases, including traumatic spinal cord injuries; ... acute abdominal symptoms indicating a serious underlying disease). Although a Journal of Emergency Medicine paper concludes: " ...
Hourigan CS (2006). "The molecular basis of coeliac disease". Clin Exp Med (Review). 6 (2): 53-59. doi:10.1007/s10238-006-0095- ... breast cancer, malignant melanoma, kidney cancer, and colon cancer (in decreasing order of frequency). ... GBD 2015 Disease and Injury Incidence and Prevalence, Collaborators. (8 October 2016). "Global, regional, and national ... Hodgson TS, Nielsen SM, Lesniak MS, Lukas RV (2016). "Neurological Management of Von Hippel-Lindau Disease". Neurologist ( ...
"In Bao Y, Fenwick R. Phytochemicals in health and disease. New York, NY: Dekker. pp. 50-67. ISBN 0-8247-4023-8.. ... In human breast cancer cell lines, quercetin has also been found to act as an agonist of the G protein-coupled estrogen ... or any disease.[2][32] The US Food and Drug Administration has issued warning letters to several manufacturers advertising ... or prevention of disease and/or articles intended to affect the structure or any function of the human body."[33][34] ...
"Microbial Ecology in Health and Disease. 30 (sup1): 1535737. doi:10.1080/16512235.2018.1535737. PMC 6225515. PMID 30425610.. ... Breast feeding babies expel soft, pale yellowish, and not quite malodorous matter; but once the baby begins to eat, and the ... Stokstad, Erik (28 July 2000). "Divining Diet and Disease From DNA". Science. 289 (5479): 530-531. doi:10.1126/science.289.5479 ... "Evidence that disgust evolved to protect from risk of disease". Proc. Biol. Sci. 271 Suppl 4 (Suppl 4): S131-3. doi:10.1098/ ...
"Domperidone and levodopa in Parkinson's disease". British journal of clinical pharmacology 18 (6): 959-62. பப்மெட்:6529536 ... Breast milk, renal அடையாளக் குறிப்புகள் CAS எண் 57808-66-9 ATC குறியீடு A03FA03 ...
In any case, common side effects of antiandrogens in men include breast tenderness, breast enlargement, feminization, hot ... Richard A. Helms; David J. Quan (2006). Textbook of Therapeutics: Drug and Disease Management. Lippincott Williams & Wilkins. ... In males, the major side effects of antiandrogens are demasculinization and feminization.[74] These side effects include breast ... Giuseppe Buonocore; Rodolfo Bracci; Michael Weindling (28 January 2012). Neonatology: A Practical Approach to Neonatal Diseases ...
"PLoS Neglected Tropical Diseases. 6 (9): e1839. doi:10.1371/journal.pntd.0001839. PMC 3459880 . PMID 23029594.. ... No study has proven presence in breast milk, but the high level of viremia suggests it may be possible.[6] ... Descriptions of the disease date from the 1950s.[1] The virus was first described in 1969 from a case in the town of Lassa, in ... The disease is usually initially spread to people via contact with the urine or feces of an infected multimammate rat.[1] ...
Myxomas may also occur outside the heart, usually in the skin and breast. Endocrine tumors may manifest as disorders such as ... endocrine gland manifestation is an ACTH-independent Cushing's syndrome due to primary pigmented nodular adrenocortical disease ...
In medicine, FISH can be used to form a diagnosis, to evaluate prognosis, or to evaluate remission of a disease, such as cancer ... MA-FISH is applied for detecting the HER2 gene in breast cancer tissues.[16] ... Examples of diseases that are diagnosed using FISH include Prader-Willi syndrome, Angelman syndrome, 22q13 deletion syndrome, ... An example is the detection of BCR/ABL translocations, where the secondary color indicates disease. This variation is often ...
... "first severe new disease of the 21st century." She observed that the two new diseases WHO is dealing with in 2013 are the novel ... International Code of Marketing of Breast-milk Substitutes, adopted in 1981. *Framework Convention on Tobacco Control, adopted ... Enhanced global actions for the prevention and control of non-communicable diseases, endorsed in 2011[8] ... combatting non-communicable diseases and female genital mutilation; campaigns to support breastfeeding and to decrease abuse of ...
The emphasis now is on explaining to the general public surgical disease, how it was treated over the centuries and how it is ... Subjects of recent exhibitions have included: breast cancer care, Charles Bell, chloroform, Joseph Lister, women's hospitals, ... In the 19th and early 20th century wax and plaster casts or moulages showing abnormalities and diseases were widely used as ... Recent research projects carried out in the Museum have included studies on genetic markers for disease, facial reconstruction ...
Disease * sw:Disease. Dmitri Mendeleev * sw:Dmitri Mendeleev. DNA * sw:DNA. Dog * sw:Dog. Dome * sw:Dome. Domestic pig * sw: ... Breast * sw:Breast. Breathing * sw:Breathing. Bridge * sw:Bridge. British Empire * sw:British Empire. Bronze Age * sw:Bronze ... Sexually transmitted disease * sw:Maradhi ya zinaa. Shāhnāma * sw:Shāhnāma. Shanghai * sw:Shanghai. Shark * sw:Shark. Sheep * ... Alzheimer's disease * sw:Ugonjwa wa Alzheimer. Amazon River * sw:Amazonas (mto). American Civil War * sw:Vita vya wenyewe kwa ...
A new study which followed 2,000 women with breast cancer for twenty-years post-diagnosis has revealed that breast cancer is ... eleven different diseases, each with a different risk of coming back after treatment. ... New research published in the journal Nature shows that breast cancer is 11 genetically distinct diseases, and each has a ... New research published in the journal Nature shows that breast cancer is 11 genetically distinct diseases, and each has a ...
Health Information on Breast Diseases: MedlinePlus Multiple Languages Collection ... Breast Diseases: MedlinePlus Health Topic - English Enfermedades del seno: Tema de salud de MedlinePlus - español (Spanish) ... Breast Biopsy - 简体中文 (Chinese, Simplified (Mandarin dialect)) Bilingual PDF ... Breast Biopsy - 繁體中文 (Chinese, Traditional (Cantonese dialect)) Bilingual PDF ...
This text is intended as a practical guide for physicians and surgeons who treat diseases of the breast, both benign and ... The management of breast diseases requires a multidisciplinary approach, and this textbook therefore includes the views of a ... This text is intended as a practical guide for physicians and surgeons who treat diseases of the breast, both benign and ... Today the treatment of breast diseases is largely predicated on the results of randomized prospective trials. The results of ...
... fibrocystic breast disease is more a characteristic of the breast than a disease. It is often more prominent during ovulation ... www.healthcentral.com/condition/fibrocystic-breast-disease. Fibrocystic Breast Disease. Fibrocystic Breast Disease. March 27, ... fibrocystic breast disease is more a characteristic of the breast than a disease. It is often more prominent during ovulation ... Fibrocystic breast disease is usually diagnosed when a patient goes to her doctor for a checkup or seeks help for pain, ...
... and intensively focused information about Breast Diseases in a compact format. The editors have built Breast Diseases: New ... The content of Breast Diseases: New Insights for the Healthcare Professional: 2011 Edition has been produced by the worlds ... You can expect the information about Breast Diseases in this eBook to be deeper than what you can access anywhere else, as well ... Breast Diseases: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, ...
... breasts. It is a very common condition and not harmful. Learn more in this article. ... Fibrocystic breast disease causes a person to have lumpy, and sometimes painful, ... breasts that feel heavy. While lumpy breasts and discomfort are common in people with fibrocystic breast disease, it is ... Symptoms of fibrocystic breast disease can include tenderness and swelling. A doctor may diagnose fibrocystic breast disease ...
Posts about fibrocystic breast disease written by What Doctors Dont Tell You, Susan M. Lark MD, and David L. Hoffmann BSc Hons ... Fibrocystic breast disease, also known as cystic mastitis or fibroadenoma, is not only common, but also worrying. Any lump or ... Research shows that thirty percent of American women have fibrocystic breast disease, a benign (non-cancerous) condition ... Fibrocystic Disease (FCD) ;Also known as chronic cystic mastitis. This is the commo ...
Breast cancer is the most common cancer among women in the U.S. and the second leading cause of cancer-related deaths among ... When cancer starts in the breast, it is called breast cancer. As it grows, breast cancer can cause changes in how the breast ... Breast Cancer in Men. Although it is rare, men can get breast cancer. Learn about symptoms of breast cancer in men and things ... Breast cancer symptoms vary, and some women dont have symptoms.. *Men can get breast cancer, but it is not very common. About ...
15 (HealthDay News) -- Young women receiving radiation after having surgery for breast cancer are at increased risk of ... developing a new tumor in the opposite -- or contralateral -- breast, a new Dutch study suggests. ... Younger Breast Cancer Survivors Risk Disease in Other Breast. By Amanda Gardner. HealthDay Reporter. Wednesday, October 15, ... In general, according to the study, women diagnosed with breast cancer in one breast have three to four times the risk of ...
Breast changes such as lumps, bumps, and discharge are common. Some causes can be aging, hormones, and medicines. Learn whats ... Fibroadenoma - breast (Medical Encyclopedia) Also in Spanish * Fibrocystic breast disease (Medical Encyclopedia) Also in ... Breast self exam (Medical Encyclopedia) Also in Spanish * Breast skin and nipple changes (Medical Encyclopedia) Also in Spanish ... ClinicalTrials.gov: Breast Diseases (National Institutes of Health) * ClinicalTrials.gov: Gynecomastia (National Institutes of ...
Pagets disease) of the breast is an uncommon type of cancer that forms around the nipple. It is usually associated with an ... underlying breast cancer. Find out about symptoms, diagnosis, prognosis, and treatment. ... These other diseases are not related to Paget disease of the breast. This fact sheet discusses only Paget disease of the breast ... breast ectasia, and breast infection. Sometimes its possible to feel breast cancer as a breast lump. The breast lump may or ...
A new analysis of data from the PALOMA-2 trial in advanced breast cancer shows that quality of life (QoL) was better for a ... "Advanced breast cancer is, for the moment, an incurable disease, and, therefore, a balance between quantity and quality of life ... Cite this: Disease Control Prolongs QoL in Advanced Breast Cancer - Medscape - Nov 06, 2017. ... "If you can slow disease progression in MBC [metastatic breast cancer] by palbociclib and endocrine therapy, it is very ...
Im experiencing an intermittent dull pain in the center of my chest that feels like its coming from my breast bone as opposed ... Can Mental Stress Lead to Heart Disease? Can depression and anxiety cause heart disease? Get the facts in this Missouri ... Heart Disease Forum This expert forum is not accepting new questions. Please post your question in one of our medical support ... Im experiencing an intermittent dull pain in the center of my chest that feels like its coming from my breast bone as opposed ...
For about a week now Ive noticed unusual pain in between my breasts as if the pain is located on the bone. It becomes painful ... Breast Bone Pain Kimmy600 For about a week now Ive noticed unusual pain in between my breasts as if the pain is located on the ... Breast Bone Pain. For about a week now Ive noticed unusual pain in between my breasts as if the pain is located on the bone. ... Can Mental Stress Lead to Heart Disease? Can depression and anxiety cause heart disease? Get the facts in this Missouri ...
Some breast cancer therapies can be hard on the heart. Experts say it shouldnt stand in the way of treatment and steps can be ... Some treatments for breast cancer can harm your heart.. And heart disease is the number one. cause of death for women in the ... Breast Cancer Treatments Can Increase Risk of Heart Disease. Written by Ann Pietrangelo. on February 8, 2018 ... In fact, breast cancer survivors, particularly women over age 65, are more likely to die from cardiovascular disease than ...
Breast Cancer Screening. Mr Oliver Young. 28th February 2018. Genetics and Genomics in Breast Cancer. Mr Ian Young. 7th March ... Radiotherapy in breast cancer. Dr Alison Stillie. 28th March 2018. Unusual presentations of breast cancer and management. Mr ... Breast Radiology. Dr Ashwini Sharma & Dr Jennifer Royds. 27th November 2017. Breast pathology for surgeons. Dr Jeremy Thomas. ... Congenital abnormalities of breast and breast infection. Professor Mike Dixon. 10th October 2017. ...
Baerbel Froehlin, a hypnotherapist, discovered a lump in her breast and immediately used one of her favorite positive ... Breast Lump Disappears. *New Drug-Free Treatment for Disease Often Works Where Nothing Else Will: From Yeast Infections to ... Parkinsons Disease*EFT provides help for two symptoms of Parkinsons Disease.. *Relieving Parkinsons symptoms, even with a ... Breast Lump Disappears Note: This is one of 3,000 articles written prior to the updated Gold Standard (Official) EFT Tapping ...
Presentation at the 4th IMPAKT Breast Cancer Conference. Breast cancer in young women is a biologically unique disease that ... whether the disease had spread to lymph nodes and breast cancer molecular subtype, in addition to other variables. ... "Young women with breast cancer tend to have a poorer prognosis. This study provides evidence that breast cancer in young women ... "As breast cancer arising below the age of 40 is relatively uncommon, we lack information on whether different gene signatures ...
Pagets disease of the breast is a rash on and around the nipple that can indicate a rare form of breast cancer. Find out what ... Pagets disease of the breast may cause tingling and itching.. The symptoms of Pagets disease vary depending on the stage of ... Pagets disease of the breast or nipple refers to breast changes that can indicate that cancer cells are forming in or around ... Around half of all people with Pagets disease of the breast also have a breast lump behind the nipple. In 90% of these cases, ...
... watchful waiting is inappropriate when a breast lesion develops or enlarges during pregnancy or lactation ... Since breast cancer complicates 1 in 3000 deliveries in the US, ... Diagnosing and Managing Breast Disease During Pregnancy and ... Diagnosing and Managing Breast Disease During Pregnancy and Lactation. MedGenMed 1(2), 1999. [formerly published in Medscape ... During pregnancy, the size and weight of the breasts approximately double as glandular elements proliferate under hormonal ...
APC of Breast Diseases: Breast Cancer - Epidemiology, risk factors, and Genetics BMJ 1994; 309 :1003 ... APC of Breast Diseases: Breast Cancer - Epidemiology, risk factors, and Genetics. BMJ 1994; 309 doi: https://doi.org/10.1136/ ... Risk Factors for Breast cancer. Age The incidence of breast cancer increases with age, doubling about every 10 years until the ... Studies of migrants from Japan to Hawaii show that the rates of breast cancer in migrants assume the rate in the host country ...
Breast cancer patients may be at an increased risk of cardiovascular diseases including heart failure and may benefit from a ... because older breast cancer survivors are more likely to die of heart disease than breast cancer," Dr. Mehta said. "And thats ... who are living with cardiovascular diseases and approximately 3 million breast cancer survivors, many people regard breast ... Breast cancer patients may be at increased risk of cardiovascular diseases. *Download PDF Copy ...
Breast cancer survivor Makieba Hatton and cardiologist Dr. Susan Gilchrist discuss on the 3rd hour of TODAY how the Healthy ... A study published by the American Heart Association says people who have had breast cancer may be at a higher risk for heart ... Program helps breast cancer patients reduce risk of heart disease. TODAY UP NEXT. * Man share battle against pancreatic cancer ... Program helps breast cancer patients reduce risk of heart disease. Duration: 04:05 10/29/2020. ...
Carcinoma of the male breast accounts for less than 1% of all malignancies in men and 0.2% of male cancer... ... Worldwide breast cancers are a common cause of concern for patients as well as for doctors. ... Pagets disease of the breast: there is a role for breast-conserving therapy. Ann Surg Oncol. 2005;12:391-7.CrossRefPubMed ... Pagets disease of the breast areola mimicking cutaneous melanoma. Breast J. 2006;12(3):233-6.CrossRefPubMedGoogle Scholar ...
Paget disease of the nipple is a rare breast cancer that appears as a rash or skin change on the nipple. Learn about symptoms, ... Paget disease of the breast. Paget disease of the breast is a rare type of breast cancer. It develops as a rash or other skin ... Cancer information / Cancer types / Breast / Breast cancer / Cancerous tumours / Paget disease of the breast ... Paget disease of the breast usually causes changes to the nipple, including:* crusting, scaling or flaking ...
... a rare type of cancer that is sometimes called Paget disease of the nipple or mammary Paget disease. ... A fact sheet about Paget disease of the breast, ... What is Paget disease of the breast?. Paget disease of the ... These other diseases are not related to Paget disease of the breast. This fact sheet discusses only Paget disease of the breast ... Who gets Paget disease of the breast?. Paget disease of the breast occurs in both women and men, but most cases occur in women ...
Women who live more than 10 years after a diagnosis of breast cancer are more likely to die of diseases other than cancer, ... Long-term breast cancer survivors die from other diseases. By Rebekah Moan, AuntMinnie.com contributing writer. December 17, ... In the past 40 years, mortality rates from breast cancer have dropped and patients may live long enough after a breast cancer ... But for those who survived, the most common cause of death after 10 years was heart disease, followed by Alzheimers disease. ...
T 0414/07 (Diseases of the breast/ABBOTT) of 3.6.2008. European Case Law Identifier:. ECLI:EP:BA:2008:T041407.20080603. ... The application, entitled Reagents and Methods Useful for Detecting Diseases of the Breast, originated from an International ... which is overexpressed in human breast cancer and believed to be a clinically useful marker for managing patients with breast ... Claim 7 was directed to a test kit useful for the diagnosis of breast cancer comprising a container containing at least one ...
... breast benign diseases are the most common cause of breast problems; up to 30% of women suffer from breast benign diseases and ... The incidence of breast benign diseases is about 5 to 10 times higher than breast cancer. Among breast benign diseases, ... the incidence of breast benign diseases is about 5 to 10 times higher than breast cancer; up to 30% of women suffer from breast ... as well as breast cancer, is absolutely essential for MPM to make real-time noninvasive diagnosing of breast diseases. In this ...
It is the most common type of breast cancer, which can spread from the milk ducts to other parts of the breast or beyond if not ... The 55-year-old lawyer and mother of three had discovered a lump in her breast last week as the presidential campaign was at ... Ginsberg said Edwards detected the lump in her right breast last Friday while on the campaign trail. Her doctor told her it ... Edwards treatment could involve removal of part or all the breast and the lymph nodes around it. That would be followed by ...
  • During these times, hormone level changes often cause the breast cells to retain fluid and develop into nodules or cysts (sacs filled with fluid), which feel like a lump when touched. (healthcentral.com)
  • Fibrocystic breast disease is usually diagnosed when a patient goes to her doctor for a checkup or seeks help for pain, tenderness or a lump that was probably discovered during breast self-examination. (healthcentral.com)
  • During the examination of the lump sample, the pathologist might see excessive fibrous growth between the breast glands or cyst formation within the glands. (healthcentral.com)
  • Fibrocystic breast disease may make it difficult to differentiate between a new breast lump and fibrocystic changes. (medicalnewstoday.com)
  • Any lump or pain in the breast raises the spectre of breast cancer. (healthy.net)
  • If you have a breast lump, pain, discharge or skin irritation, see your health care provider. (medlineplus.gov)
  • Sometimes it's possible to feel breast cancer as a breast lump. (medicinenet.com)
  • The breast lump may or may not be painful or tender. (medicinenet.com)
  • Baerbel Froehlin, a hypnotherapist, discovered a lump in her breast and immediately used one of her favorite positive suggestion techniques to help her body in its own healing. (emofree.com)
  • Two years ago I was scheduled to have a biopsy because my doc had detected a lump in my breast. (emofree.com)
  • When I went into the hospital for my biopsy, the doctor was not able to find the lump in my breast and I went home, filled with relief, joy and incredible motivation. (emofree.com)
  • Around half of all people with Paget's disease of the breast also have a breast lump behind the nipple. (medicalnewstoday.com)
  • As many as 50 percent of people who have Paget disease of the breast have a breast lump that can be felt in a clinical breast exam. (cancer.gov)
  • The 55-year-old lawyer and mother of three had discovered a lump in her breast last week as the presidential campaign was at its peak, and doctors urged her to be tested as soon as possible, her spokesman, David Ginsberg, said. (nypost.com)
  • Ginsberg said Edwards detected the lump in her right breast last Friday while on the campaign trail. (nypost.com)
  • For many types of breast cancer, the first symptom is a lump in the breast. (healthline.com)
  • Learn what a breast cancer lump feels like. (healthline.com)
  • Some women will delay having a breast lump evaluated. (forbes.com)
  • You may have a lump in the same area of the breast that becomes larger before each period and shrinks afterward. (umm.edu)
  • This type of lump is common with fibrocystic breasts. (umm.edu)
  • You may need further tests if a lump was found during a breast exam or your mammogram result was abnormal. (umm.edu)
  • I found a lump in my breast at age 42. (nytimes.com)
  • Painful tender breast lump, either solitary or more commonly multiple tender lumps, usually in upper outer quadrants of the breast. (rxmed.com)
  • One of these subgroups has an initially poor prognosis, but if successfully treated, the disease is unlikely to come back in those who survived five years post-diagnosis. (forbes.com)
  • Conversely, they also found a group of patients with estrogen-receptor positive tumors who generally have a more favorable initial prognosis than those with triple-negative, but have a higher risk of a very late relapse of disease up to 20 years post-diagnosis. (forbes.com)
  • Most of the time the diagnosis of fibrocystic breast characteristics does not require extensive testing. (healthcentral.com)
  • Diagnosis of Paget disease of the breast is confirmed by a biopsy, a sample of tissue taken for laboratory analysis and diagnosis. (medicinenet.com)
  • The average age at diagnosis is 57 years, but the disease has been found in adolescents and in people in their late 80s. (medicinenet.com)
  • They adjusted their findings to take into account the size of the tumor at diagnosis, whether the disease had spread to lymph nodes and breast cancer molecular subtype, in addition to other variables. (redorbit.com)
  • Both immunohistochemistry and breast magnetic resonance imaging methods are complementary and should be correlated to confirm or exclude a diagnosis of Paget's disease. (springer.com)
  • The objective of this chapter is to provide an overview of Paget's disease and to describe the etiopathogenesis, clinicopathological features, differential diagnosis, and recent diagnosis and treatment modalities of Paget's diseases of the nipple in the male breast with cancer. (springer.com)
  • December 17, 2019 -- Women who live more than 10 years after a diagnosis of breast cancer are more likely to die of diseases other than cancer, such as heart and cerebrovascular diseases, according to a large study published online on December 16 in Cancer . (auntminnie.com)
  • They found that of women who died from breast cancer, most deaths occurred within one to five years after diagnosis. (auntminnie.com)
  • In the past 40 years, mortality rates from breast cancer have dropped and patients may live long enough after a breast cancer diagnosis that noncancer-related comorbidities may significantly affect their overall survival. (auntminnie.com)
  • Conversely, 16.3% of the deaths occurred within less than a year of breast cancer diagnosis. (auntminnie.com)
  • While over 50% of women who died within the first five years of diagnosis died of breast cancer, that percentage dropped to less than a quarter among those who survived 10 years. (auntminnie.com)
  • The researchers also found that patients diagnosed with breast cancer between the ages 40 and 64 -- as well as black patients with breast cancer -- seemed to have a higher risk of septicemia and cardiac disease within the first year after diagnosis compared with the general U.S. population. (auntminnie.com)
  • White patients had a statistically significant higher risk of death from chronic liver diseases and cirrhosis within the first year after cancer diagnosis compared with the general U.S. population, whereas Native American/Alaska Native patients had a significantly higher risk of death from chronic obstructive pulmonary disease. (auntminnie.com)
  • Claim 7 was directed to a test kit useful for the diagnosis of breast cancer comprising a container containing at least one polynucleotide having a sequence as defined in claim 1. (epo.org)
  • These findings indicate that, with integration of MPM into currently accepted clinical imaging system, it has the potential to make a real-time diagnosis of breast benign diseases in vivo, as well as breast cancer. (hindawi.com)
  • Keep reading and find out how to identify Paget's disease of the breast and why diagnosis is often delayed. (healthline.com)
  • And upon receiving a breast cancer diagnosis, a person might decline appropriate oncology care. (forbes.com)
  • Coupled with updates to BI-RADS, current practices reflect the indispensable nature of ultrasound to breast disease diagnosis and management. (springer.com)
  • The number of premalignant breast cells in apoptosis at the time of diagnosis will be compared to the number of cells in apoptosis following treatment with 15 (+/- 5) days of ruxolitinib or placebo. (clinicaltrials.gov)
  • The researchers identified women with a primary breast cancer diagnosis in 2006-2011, and no prior cancer history who were then classified with or without hyperthyroidism and hypothyroidism. (endocrineweb.com)
  • With the use of mammography, ultrasound, and magnetic resonance imaging of the breast and the extensive use of needle biopsies, the diagnosis of a benign breast disease can be accomplished without surgery in the majority of patients. (health.am)
  • However, an anatomic location outside the milk line should not preclude a diagnosis of ectopic breast tissue, because there are many well-documented, unusual sites of such tissue, including the knee, lateral thigh, buttock, face, ear, and neck. (health.am)
  • When Pat Messick received the diagnosis, she became one of the people she had always read about: a victim of breast cancer. (baltimoresun.com)
  • Not only are these women's presumably healthy breasts being exposed to highly carcinogenic x-rays, but thousands have received a diagnosis of 'breast cancer' for entirely benign lesions that when left untreated would have caused no harm to them whatsoever. (greenmedinfo.com)
  • According to the researchers, who looked at 24 breast cancer samples, the study findings will help doctors do a better job of classifying tumors, which will improve the diagnosis and treatment of breast cancer. (bio-medicine.org)
  • Practice monthly breast self-examination to check breasts for lumps and changes in lumps after diagnosis. (rxmed.com)
  • The clinical diagnosis of stage 3 breast cancer is often obvious, but delay in diagnosis may occur in certain cases, for example in inflammatory breast cancer which can mimic cellulitis, and in pregnancy. (thefreelibrary.com)
  • It can be scary for a woman to know that she has a family history of the disease, but after diagnosis, what's her prognosis compared with patients without a family history? (newswise.com)
  • Previous research by the group showed that by analyzing the DNA of breast cancers, they can actually be considered to be 11 distinct diseases. (forbes.com)
  • About 1 out of every 100 breast cancers diagnosed in the United States is found in a man. (cdc.gov)
  • The genomic analysis also identified a number of signaling pathways in the breast cancers of young women that could be potential targets for treatment, Dr Azim's group reports. (redorbit.com)
  • With 570 000 new cases in the world each year, breast cancer remains the commonest malignancy in women and comprises 18% of all female cancers. (bmj.com)
  • Worldwide breast cancers are a common cause of concern for patients as well as for doctors. (springer.com)
  • Afifi and colleagues added that the study emphasizes the importance for breast cancer survivors of following proper screening and preventive measures for other cancers. (auntminnie.com)
  • We do know that it represents a small portion of all breast cancers, and it's seen in between 1 and 4 percent of breast cancer cases. (healthline.com)
  • According to the NCI , half of breast cancers are found in women younger than age 62. (forbes.com)
  • In a new study published in the Journal of Hepatology , researchers identified links not only between NAFLD and hepatocellular carcinoma (HCC), which have been well established, but also to cancers outside the liver, including colorectal and breast cancer. (elsevier.com)
  • Further studies are needed to specify which high-risk groups among patients with NAFLD carry a greater risk of developing specific cancers, including HCC, colorectal cancer, and breast cancer and that we should pay more attention to the cancer potential of NAFLD in clinical practice. (elsevier.com)
  • 2 This study confirmed that their data reflected higher fT4 levels were associated with an elevated risk of breast cancer, as well as any solid, non skin cancer, cancers of the gastrointestinal tract and lungs. (endocrineweb.com)
  • According to Mark W. Clemens , M.D., associate professor, Plastic Surgery and senior investigator, the team looked at "certain rare diseases" and found an association with some autoimmune diseases and cancers, including scleroderma and melanoma. (mdanderson.org)
  • Since 1994, scientists have known that mutations in the BRCA gene can contribute to a higher risk of developing breast and ovarian cancers. (time.com)
  • We will be laser-focused on diseases for which there are no known cure and have a poor prognosis, such as hard-to-treat cancers and incurable human genetic disease," Disney says. (scripps.edu)
  • Most breast cancers (22 of 26) arose within or at the margin of the radiation field and were infiltrating ductal carcinomas. (uni-bonn.de)
  • IMPLICATIONS: The high RR for development of breast cancer in women exposed to therapeutic radiation under 30 years of age raises important issues about optimal treatment strategies for patients with Hodgkin's disease, breast cancer, and other cancers. (uni-bonn.de)
  • The other important point is that the treatments for cancer are, in some cases, worse than the disease and that secondary cancers are often a result of the treatment of the first cancer. (bcaction.org)
  • How we think and talk about breast cancer and other cancers clearly has implications for how we address the disease. (bcaction.org)
  • We have looked at the level of the DNA sequence at just how splintered and reorganized the genome is in many breast cancers. (bio-medicine.org)
  • It looks as though some breast cancers have a defect in the machinery that maintains and repairs DNA, and this defect is resulting in large numbers of these abnormalities," said the institute's Dr. Andy Futreal, in the news release. (bio-medicine.org)
  • Identifying the underlying mutated cause will be central to working out how some breast cancers develop. (bio-medicine.org)
  • In recent years, there is increased interests in exploring the relationship between periodontal disease and cancer risk, particularly for cancers in the head and neck, upper gastrointestinal system, lung, and pancreas ( 6 - 9 ). (frontiersin.org)
  • Among the female-specific malignancies, breast cancer remains the most common cancer type in developed countries, accounting for one-third of newly diagnosed cancers ( 10 ). (frontiersin.org)
  • The number one cause of death for women in the U.S. is heart disease, followed by all cancers, among which breast cancer ranks as the second-most deadly. (self.com)
  • As many as 1 in 3 women die each year from cardiovascular disease or stroke -more than from all cancers combined. (self.com)
  • Breast tissue retains fluid and grows larger. (healthcentral.com)
  • Fibrocystic breast disease is a name for healthy breast tissue that feels lumpy and may be painful at times. (medicalnewstoday.com)
  • Breast tissue responds to fluctuating levels of hormones, especially estrogen . (medicalnewstoday.com)
  • Research shows that thirty percent of American women have fibrocystic breast disease, a benign (non-cancerous) condition characterized by round lumps that move freely within the breast tissue. (healthy.net)
  • The hallmark sign of Paget disease of the breast is the presence of certain malignant cells known as Paget cells, which are visible on microscopic examination of the tissue biopsy. (medicinenet.com)
  • The histology reflects preparation for lactation, with an excess of glandular elements over stroma (in contrast to "resting" breast tissue, where stroma predominates). (medscape.com)
  • The results show that MPM has the capability to identify the microstructure of lobule and stroma in normal breast tissue, the interaction of compressed ducts with surrounding collagen fiber in fibroadenoma, and the architecture of cysts filled with cystic fluid in fibrocystic disease. (hindawi.com)
  • Within breast tissue, many endogenous fluorophores including collagen bundles, nicotinamide adenine dinucleotide hydrogen (NAD(P)H), and flavin adenine dinucleotide (FAD) can easily generate strong TPEF signals, and collagen fibers with noncentrosymmetric molecular structure are more effective in producing SHG signals. (hindawi.com)
  • You have dense breast tissue . (healthline.com)
  • This is a procedure in which a needle is used to obtain a small sample of breast tissue from a nipple, areola, or tumor. (healthline.com)
  • Once study participants have completed their ruxolitinib or placebo, participants will undergo surgery to remove the premalignant breast tissue. (clinicaltrials.gov)
  • In vitro studies have shown that high level thyroid hormones have estrogen-like effects and seem to play a role in oncogenic pathways, including that of breast tissue, which gave rise to Dr. Weng's research. (endocrineweb.com)
  • For women under 35, a may be used to look more closely at breast tissue. (umm.edu)
  • Ectopic breast (mammary heterotopia), which has been described as both supernumerary and aberrant breast tissue, is the most common congenital abnormality of the breast. (health.am)
  • Aberrant breast tissue is usually located near the breast, most commonly in the axilla. (health.am)
  • When the nipple is absent, the presence of the accessory breast tissue is difficult to identify. (health.am)
  • The accessory breast tissue responds in the same way as normal breast tissue to physiological influences. (health.am)
  • Accessory breast tissue and polymastia are more common among Asians, especially Japanese, than whites. (health.am)
  • Recognition of ectopic breast tissue is important because it can serve as a milieu for the development of a variety of benign and malignant lesions encountered in the normal breast. (health.am)
  • The most common signs of fibrocystic breasts include lumpiness, tenderness, cysts (packets of fluid), areas of thickening, fibrosis (scar-like connective tissue), and breast pain . (imaginis.com)
  • Fibrocystic breast lumps tend to be smooth, rounded, and mobile (not attached to other breast tissue), though some fibrocystic tissue may have a thickened, irregular feel. (imaginis.com)
  • Serum and tissue LDH levels in patients with breast/gynaecological cancer and benign diseases. (nih.gov)
  • We investigated comparatively the total serum LDH activity and tissue isoenzyme LDH5 and hypoxia-inducible factor 1alpha (HIF1alpha) levels in patients with breast (n = 18) and gynaecological (n = 23) malignancies and benign diseases (n =54). (nih.gov)
  • Serum and tissue LDH is up-regulated in gynaecologic and breast malignancies and in a subset of benign conditions such as fibro- and cystadenomas. (nih.gov)
  • New technology from Purdue University innovators may help improve tissue restoration outcomes for people with breast cancer and other diseases or traumatic injuries. (purdue.edu)
  • Purdue researchers, along with fellowship-trained breast surgeon Carla Fisher of Indiana University School of Medicine, teamed up with Purdue startup GeniPhys to develop and perform preclinical studies on a regenerative tissue filler. (purdue.edu)
  • Such an approach may also benefit other patient populations in need of soft tissue restoration or reconstruction, including children with congenital defects, individuals with difficult-to-heal skin ulcers, individuals suffering from traumatic injuries and cancer patients requiring resection of tumors within tissues other than breast. (purdue.edu)
  • The regenerative tissue filler, when applied to breast tissue voids, such as those associated with breast conserving surgery, restored breast shape and consistency and supported new breast tissue formation over time, including mammary glands, ducts and adipose tissue. (purdue.edu)
  • Method of treating breast disease, including cancer, with a formula and a means of delivery with a topical, intraductal, ductal, and/or intraductal infusion to prevent the formation of cancer or precursors to cancer or atypia or other form of abnormal breast tissue or to treat breast diseases of all kinds. (freepatentsonline.com)
  • May include homeopathic remedies to be used topically or inside the breast with a delivery method to those regions and may be processed with or without photonic programming or an ionic delivery system for greater effectiveness and use against degenerative diseases or cancerous or precancerous diseases, precursors of breast disease, inflammatory breast disease, or accumulation of toxins in the breast tissue. (freepatentsonline.com)
  • This formula and method of its delivery is to treat abnormal breast tissue or other region of the body to be treated, or to prevent the formation of cancer or precursors to cancer or atypia or other form of abnormal breast or other tissue before it spreads or becomes breast cancer and causes metastasis to the brain, liver, bone and other parts of the body. (freepatentsonline.com)
  • The most definitive study yet of the health effects of silicone breast implants has found no association between the implants and connective tissue diseases. (baltimoresun.com)
  • They analyzed data from June 1976 through May 1990, before an avalanche of lawsuits over purported links between silicone breast implants and connective tissue diseases. (baltimoresun.com)
  • The investigators found that women with implants were, if anything, slightly less likely to develop connective tissue diseases such as rheumatoid arthritis, or even to complain of signs and symptoms of disease that resembled those of connective tissue diseases but fell short of meeting the standard diagnostic criteria. (baltimoresun.com)
  • Another study, by researchers at the Mayo Clinic in Rochester, Minn., found no evidence that women with implants had developed any specific connective tissue disease. (baltimoresun.com)
  • Dr. Colditz said he and his colleagues conducted the study in response to growing public alarm over a possible link between implants and connective tissue diseases. (baltimoresun.com)
  • At that time, some women with implants had developed connective tissue diseases, including rheumatoid arthritis, lupus and scleroderma, but there was no proof that the implants had caused the diseases. (baltimoresun.com)
  • Although the FDA was careful to say there was no scientific evidence linking implants and connective tissue diseases, the moratorium fueled the litigation. (baltimoresun.com)
  • The illnesses usually did not fit he standard definitions of connective tissue diseases, but the women's doctors and lawyers said the implants had caused not only classic connective tissue diseases, but also a new sort of disease, with symptoms resembling those of standard diseases but not quite fulfilling standard diagnostic criteria. (baltimoresun.com)
  • ConclusionAn Edinburgh-based team used mice engineered to develop breast cancer to better understand how it spreads from breast tissue to the lung, where it can be fatal. (medworm.com)
  • The breasts are composed of several cell and tissue types, which can be broadly classified as either epithelial or stromal. (gponline.com)
  • The texture of breast tissue is seldom uniform and generalised thickening, often referred to as nodularity, is common. (gponline.com)
  • Breast biopsy involves removing a sample of breast tissue to determine whether it is cancerous or benign. (medindia.net)
  • The condition affects the breasts of women, giving the tissue a ropey or lumpy texture. (earthclinic.com)
  • If you have fibrocystic breast tissue, you will probably experience moderate to severe breast pain as well as unusual breast tissue and even structure. (earthclinic.com)
  • Thyroid function is closely linked to fibrocystic breast tissue. (earthclinic.com)
  • Supplementing with iodine is an effective way to reduce pain, limit cyst development, and eliminate the side effects of thyroid dysfunction on breast tissue. (earthclinic.com)
  • Try taking iodine pills or Lugol's iodine drops as directed to treat fibrocystic breast tissue. (earthclinic.com)
  • Removing caffeine from your diet is actually the most well-known alternative remedy for fibrocystic breast tissue. (earthclinic.com)
  • Caffeine influences breast tissue, causing enlargement and swelling of individual nodules. (earthclinic.com)
  • Reducing your intake of the drug limits the appearance of fibrocystic tissue in your breasts. (earthclinic.com)
  • Fibrocystic breast tissue does not increase your risk of breast cancer. (earthclinic.com)
  • However, you should maintain a regular schedule of breast exams and mammograms to keep track of tissue development and determine the cause of breast changes. (earthclinic.com)
  • Introduction: Mammographic breast density is dependent on the relative proportion of radiolucent fat and radio-dense connective and glandular tissue. (iospress.com)
  • The goals of this research are to increase scientific understanding of early changes in breast tissue, and learn how to better screen, diagnose and treat each individual cancer patient. (vancouverobserver.com)
  • It has since been elucidated that androgens like testosterone and dihydrotestosterone (DHT) function as trophic factors for the prostate gland, stimulating cell division and proliferation and producing tissue growth and glandular enlargement, which, in the context of prostate cancer, results in stimulation of tumors and a considerable acceleration of disease progression. (wikipedia.org)
  • It is hoped that stratifying breast cancer patients in this more detailed way could lead to better personalized medicine approaches, reducing the number of people who relapse as well as reassuring those with a very low risk of relapse. (forbes.com)
  • The doctor will examine the breasts and sometimes recommend a mammogram, an ultrasound exam and (rarely) a needle aspiration. (healthcentral.com)
  • A woman may find out she has breast cancer after a routine mammogram. (cdc.gov)
  • A mammogram can't prevent breast cancer, but it can help find it early. (cdc.gov)
  • Computer enhanced mammogram of a breast cancer. (bmj.com)
  • Benign breast disease can be found during self-exam, an exam by a doctor, or by a mammogram. (breastcancer.org)
  • It's likely that your doctor will also order a diagnostic mammogram to look for signs of breast cancer. (healthline.com)
  • Another mammogram and breast ultrasound may be done. (umm.edu)
  • However, screening mammography may be more difficult to perform on women with fibrocystic breasts because the breast density associated with fibrocystic breasts may eclipse breast cancer on the mammogram film. (imaginis.com)
  • Women participating in the study had a mammogram, physical examination, breast examination, and blood draw, and completed a questionnaire on diet and lifestyle factors. (clinicaltrials.gov)
  • Mid-lateral mammogram of the right breast shown in the upper outer quadrant in a radiopaque mass with margins irregular and speculated. (hindawi.com)
  • My mammogram revealed a Rice Krispie-size lesion in my fibrocystic breasts. (nytimes.com)
  • A medio-lateral mammogram revealed a homogeneous, dense, well-circumscribed lesion in the right breast (Figure 1). (medworm.com)
  • For now the most important thing any woman can do to reduce her risk of dying from breast cancer is to have regular mammogram screening, learn how to perform breast self exams, and have a regular physical examination by their physician. (peoples-health.com)
  • A nipple biopsy allows doctors to correctly diagnose Paget disease of the breast. (cancer.gov)
  • In addition to ordering a nipple biopsy, the doctor should perform a clinical breast exam to check for lumps or other breast changes. (cancer.gov)
  • Your doctor might recommend a biopsy or surgery to diagnose and remove the benign disease. (breastcancer.org)
  • The only way to confirm breast cancer is with a biopsy . (healthline.com)
  • The questions ask about risk factors such as age, child-bearing history, family history of breast cancer, and breast biopsy results. (breastcancer.org)
  • 17% of the women had had a previous breast biopsy. (breastcancer.org)
  • Have a breast biopsy showing ADH (atypical ductal hyperplasia), ALH (atypical lobular hyperplasia), LCIS (lobular carcinoma in situ), or DCIS (ductal carcinoma in situ) requiring surgical excision. (clinicaltrials.gov)
  • D- breast biopsy when clinically indicated as per hospital policy. (clinicaltrials.gov)
  • Women who have a breast biopsy that is benign must discuss the possibility of additional risks with their doctors. (emaxhealth.com)
  • Each year in the United States it is estimated that more than 1 million women have a breast biopsy with benign findings, and Dr. Hartmann encourages clinicians to look more closely at the type of lesions they find. (emaxhealth.com)
  • The Mayo team is evaluating various possible risk factors for a later breast cancer, including age at benign biopsy, family history of breast cancer and the pathologic findings of the benign lesion. (emaxhealth.com)
  • The study population of 9,087 women was drawn from the Mayo Clinic Surgical and Pathology Indices, identifying women ages 18 to 85, who had a biopsy of a benign breast lesion during a 25-year period from Jan. 1, 1967, through Dec. 31, 1991. (emaxhealth.com)
  • The changes typically occur in both breasts, but lumps and pain may be worse in one breast than the other. (medicalnewstoday.com)
  • During the exam, the doctor feels each breast to check for lumps or abnormal areas. (medicalnewstoday.com)
  • Fibrocystic breast changes tend to feel different from the lumps associated with breast cancer. (medicalnewstoday.com)
  • Your age, hormone levels, and medicines you take may cause lumps, bumps, and discharges (fluids that are not breast milk). (medlineplus.gov)
  • Your doctor will observe the appearance of your breasts, especially around the nipples, and check for lumps or unusual thickening. (healthline.com)
  • You find new or different lumps during your breast self-exam . (umm.edu)
  • Fibrocystic breast condition is the most common cause of non-cancerous breast lumps in women between 30 and 50 years of age. (imaginis.com)
  • Some women with fibrocystic breasts only experience mild breast pain and may not be able to feel any breast lumps when performing breast self-exams . (imaginis.com)
  • Other women with fibrocystic breasts may experience more severe breast pain or tenderness and may feel multiple lumps in their breasts. (imaginis.com)
  • Most fibrocystic breast lumps are found in the upper, outer quadrant of the breasts (near the axilla, armpit, region), although these lumps can occur anywhere in the breasts. (imaginis.com)
  • The lumps or irregularities associated with fibrocystic breasts are often tender to touch and may increase or decrease in size during the menstrual cycle. (imaginis.com)
  • Benign breast disease refers to any lumps or mammographically-detected abnormalities that have been biopsied and found to not contain cancerous cells. (emaxhealth.com)
  • Cysts are relatively common breast lumps. (gponline.com)
  • The majority of palpable solid breast lumps in young women are benign proliferative lesions called fibroadenomas. (gponline.com)
  • Fibrocystic breast disease is a generalized term for non- malignant lumps in breasts, causing pain. (rxmed.com)
  • Fibrocystic breast disease is the most frequent cause of lumps in the breast. (rxmed.com)
  • Causes of benign breast disease are unknown, but lumps are probably sustained by estrogen and possibly also related to dietary fat and caffeine intake. (rxmed.com)
  • In fact, breast cancer survivors, particularly women over age 65, are more likely to die from cardiovascular disease than breast cancer, according to an American Heart Association Scientific Statement . (healthline.com)
  • A woman's risk of cardiovascular disease goes up with menopause. (healthline.com)
  • Breast cancer survivors , especially older women over the age of 65, are more likely to die from cardiovascular disease than breast cancer, underscoring the importance of effectively managing heart disease risk factors during and following cancer treatment. (news-medical.net)
  • The publication explores the shared risk factors for breast cancer and cardiovascular disease and the cardiotoxic effects of breast cancer treatments. (news-medical.net)
  • It goes on to recommend strategies to minimise the risk of cardiovascular disease in patients with breast cancer. (news-medical.net)
  • Cardiovascular disease is the leading cause of mortality in women, accounting for 1 in 3 deaths. (news-medical.net)
  • Older postmenopausal breast cancer survivors are now more likely to die of diseases other than breast cancer, and cardiovascular disease is the most common cause of death. (news-medical.net)
  • Furthermore, women who have had breast cancer are more likely to die from cardiovascular disease than women without a history of breast cancer. (news-medical.net)
  • The AHA press release says this: "Breast cancer survivors, especially older women over the age of 65, are more likely to die from cardiovascular disease than breast cancer. (forbes.com)
  • It is associated with metabolic syndrome (i.e. insulin resistance and diabetes) and predisposes to cardiovascular disease. (elsevier.com)
  • Is it merely a bystander - a manifestation of the metabolic syndrome resulting in cardiovascular disease - or is it a liver disease in its own right? (elsevier.com)
  • The risk of having a heart attack, heart failure or other major cardiovascular disease was 20 percent greater among women taking an aromatase inhibitor (AI) than those taking another drug called tamoxifen, an analysis of 29,000 breast cancer patients has found. (livescience.com)
  • Screening and medications for cholesterol to help prevent cardiovascular disease. (uhc.com)
  • The United States Preventive Services Task Force recommends that adults without a history of cardiovascular disease use low- to moderate-dose intensity statins for primary prevention of cardiovascular disease when certain risk factors are identified. (uhc.com)
  • Prior authorization will be required (with exception of lovastatin) to ensure that the member is using the medication for primary prevention of cardiovascular disease and has the noted risk factors. (uhc.com)
  • Existing epidemiological studies have linked periodontal disease to numerous systemic conditions, such as cardiovascular disease ( 1 ), preterm birth ( 2 ), osteoporosis ( 3 ), and diabetes mellitus ( 4 ), all of which may be attributed to systemic infection and inflammation ( 5 ). (frontiersin.org)
  • WEDNESDAY, Oct. 15 (HealthDay News) -- Young women receiving radiation after having surgery for breast cancer are at increased risk of developing a new tumor in the opposite -- or contralateral -- breast, a new Dutch study suggests. (washingtonpost.com)
  • According to the American Cancer Society, radiation therapy is usually employed to destroy lingering cancer cells after a lumpectomy (also known as breast-conserving surgery), after a mastectomy involving a tumor larger than 5 centimeters in size, or when cancer is found in the lymph nodes. (washingtonpost.com)
  • However, women treated with radiation before they turned 45 had a slightly increased risk of a new tumor in the other breast, while women receiving radiation before they were 35 had a 78 percent increased risk. (washingtonpost.com)
  • The cause of Paget disease of the breast is poorly understood, but it may be related to tumor cells from other sites in the breast traveling through the milk ducts to the nipple . (medicinenet.com)
  • The most widely accepted theory is that cancer cells from a tumor inside the breast travel through the milk ducts to the nipple and areola. (medicinenet.com)
  • This would explain why a few people develop Paget disease of the breast without having a tumor inside the same breast. (cancer.gov)
  • Therefore, MPM attracts increasing attentions and investigations in the field of breast cancer including observing tumor initiation, monitoring tumor progression, and detecting tumor metastasis [ 7 - 10 ]. (hindawi.com)
  • We found earlier that high-dose chemotherapy with Allo-SCT produced a tumor response in patients with chemorefractory metastatic breast cancer. (nature.com)
  • Introduction: With the emerging importance of the tumor immune environment in both invasive and preinvasive breast cancer, vaccine therapy may provide a well-tolerated, durable therapy for preinvasive breast cancer by preventing both recurrent preinvasive disease and progression to invasive disease. (washington.edu)
  • Essentially we've moved from knowing what a breast tumor looks like under a microscope to pinpointing its molecular anatomy," he said. (asiaone.com)
  • For the genetic study, Caldas's team worked with the BC Cancer Agency, based in Vancouver, Canada, and analyzed 2,000 tumor samples taken from women diagnosed with breast cancer between five and 10 years ago. (asiaone.com)
  • Among these uncommon clinical aspects, there is mammarian granulomatous lymphadenitis which may appear as a mastitis or a solitary intraparenchymal mass, giving the impression of a breast tumor. (hindawi.com)
  • The mean time to ipsilateral breast tumor recurrence (IBTR) was 2.9 years. (cancernetwork.com)
  • The phase III National Surgical Adjuvant Breast and Bowel Project (NSABP) B-39 trial is currently ongoing and is asking a similar question, but in a large 4,000-patient study-does APBI limited to the region of the tumor bed after a lumpectomy provide equivalent local tumor control compared with conventional WBI in the management of early-stage breast cancer? (cancernetwork.com)
  • Gnant said denosumab likely helps reduce the risk of breast cancer recurrence by keeping dormant tumor cells from becoming active. (health.com)
  • because it takes several months or even a year for a tumor to get large enough to feel in the breast. (peoples-health.com)
  • Having fibrocystic breasts does not place women at a higher or lower risk of developing breast cancer. (healthcentral.com)
  • What Are Fibrocystic Breasts? (imaginis.com)
  • Having fibrocystic breasts, in and of itself, is not a risk factor for breast cancer. (imaginis.com)
  • Fibrocystic breast condition is most common among women between the ages of 30 and 50, although women younger than 30 may also have fibrocystic breasts. (imaginis.com)
  • In the past, many physicians have referred to fibrocystic breasts, or lumpy breasts, as 'fibrocystic breast disease. (imaginis.com)
  • In fact, since fibrocystic breasts are so common among women during their reproductive years, some physicians do not even like to label the symptoms as a 'condition. (imaginis.com)
  • Fibrocystic breasts occur from changes in the glandular and stromal (connective) tissues of the breast. (imaginis.com)
  • Women with fibrocystic breasts often have bilateral cyclic breast pain or tenderness that coincides with their menstrual cycles. (imaginis.com)
  • Symptoms of fibrocystic breasts usually stop after menopause but may be prolonged if a woman takes hormone replacement therapy . (imaginis.com)
  • How Are Fibrocystic Breasts Diagnosed? (imaginis.com)
  • Fibrocystic breasts are often first noticed by the woman, and further investigated by her physician. (imaginis.com)
  • Breast tenderness, pain, and/or lumpiness are common indicators of fibrocystic breasts, especially when they coincide with menstruation. (imaginis.com)
  • Often, fibrocystic breasts will be diagnosed with a physician-performed clinical breast exam alone. (imaginis.com)
  • While having fibrocystic breasts is usually not a risk factor for breast cancer, the condition can sometimes make breast cancer more difficult to detect. (imaginis.com)
  • Therefore, in some cases, breast imaging exams, such as mammography or ultrasound , will need to be performed on women who show symptoms of fibrocystic breasts. (imaginis.com)
  • This text is intended as a practical guide for physicians and surgeons who treat diseases of the breast, both benign and malignant. (springer.com)
  • The prognosis and survival rate for Paget disease of the breast depend upon the extent of spread of the cancer and the presence or absence of malignant tumors in the same breast. (medicinenet.com)
  • Malignant cells known as Paget cells are a telltale sign of Paget disease of the breast. (medicinenet.com)
  • Reed W, Oppedal BR, Eeg Larsen T. Immunohistology is valuable in distinguishing between Paget's disease, Bowen's disease and superficial spreading malignant melanoma. (springer.com)
  • Understandably, a great deal of research is dedicated to the identification of sonographic manifestations of malignant breast disease. (springer.com)
  • Best utilization of rapidly evolving ultrasound technology requires comprehensive knowledge of technique, lexicon, current practice patterns, and mastery of clinical and imaging manifestations of benign and malignant disease. (springer.com)
  • Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA. Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. (springer.com)
  • however, benign lesions of the breast are far more frequent than malignant ones. (health.am)
  • The incidence of benign breast lesions begins to rise during the second decade of life and peaks in the fourth and fifth decades, as opposed to malignant diseases, for which the incidence continues to increase after menopause, although at a less rapid pace. (health.am)
  • Automated Classification of Benign and Malignant Proliferative Breast Lesions. (harvard.edu)
  • The findings of this study, showing that a lifelong history of irregular (and hence more likely anovular) cycles was less frequent among women with benign and malignant breast diseases, support the hypothesis that frequent ovular cycles might be more carcinogenic than anovular ones. (nih.gov)
  • The results of many clinical trials are discussed in detail, and readers will find this book to be a useful guide to the evidence-based treatment of breast diseases. (springer.com)
  • Doing monthly breast self-exams and following a doctor's recommendations for clinical exams and mammograms can help catch any harmful changes early. (medicalnewstoday.com)
  • A doctor may diagnose fibrocystic breast disease after a clinical breast exam and a review of symptoms. (medicalnewstoday.com)
  • Advanced breast cancer is, for the moment, an incurable disease, and, therefore, a balance between quantity and quality of life is of extreme importance to patients," said conference chair Fatima Cardoso, MD, director of the breast unit here at the Champalimaud Clinical Center, in a statement. (medscape.com)
  • Dr. Paula Klein , medical director of Breast Cancer Clinical Trials at Mount Sinai Health System in New York, told Healthline that Adriamycin, also known as the "red devil," is commonly incorporated into aggressive treatment programs. (healthline.com)
  • The researchers from Institut Jules Bordet are in fact planning a clinical trial in which premenopausal breast cancer patients will receive two injections of a drug called denosumab, which is a RANK-ligand inhibitor, one week before surgery. (redorbit.com)
  • This is clinically relevant as it underscores that these gene signatures could identify women below the age of 40 with ER+ disease who are at a low risk of relapse independent of clinical prognostic tools," Dr Azim explained. (redorbit.com)
  • The surgical treatment of Paget's disease is always under debate, but it should be selected on the basis of clinical and radiological assessment as well as extent of involvement of cancer. (springer.com)
  • Even though the clinical and pathological description of breast cancer in men is similar to that of women, considering prognosis, men seems to have worst prognosis. (springer.com)
  • Breast Paget disease: clinical, histopathological and immunohistochemical aspects. (springer.com)
  • However, recognition of clinical and imaging characteristics that support benign diagnoses is equally integral to accurate, cost-effective management of breast disease. (springer.com)
  • Between January 1999 and December 2006, 19 patients with metastatic breast cancer were enrolled in this prospective clinical trial of fludarabine and melphalan with Allo-SCT at The University of Texas M.D. Anderson Cancer Center. (nature.com)
  • Patients with bone involvement were eligible if they had stable disease (SD) that showed clinical improvement. (nature.com)
  • In Amir's study, he and his colleagues conducted a meta-analysis of all seven of the large clinical trials that have compared tamoxifen and AIs, involving more than 29,000 breast cancer patients. (livescience.com)
  • Benign diseases of the breast are common clinical conditions that affect young women. (clinicaltrials.gov)
  • In this study, the investigators will systematically collect epidemiological, developmental and clinical data in young patients presenting with breast complaints. (clinicaltrials.gov)
  • A longitudinal study of the prevalence and characteristics of breast disorders detected by clinical breast examination during pregnancy and six months postpartum in Ibadan, Southwestern Nigeria. (harvard.edu)
  • Expand your knowledge of every aspect of breast diseases as a diverse and distinguished group of internationally-recognized experts summarize the current knowledge, including biology and epidemiology, clinical features, and management. (r2library.com)
  • Algorithms on problem management in all aspects of breast disease from benign processes to breast carcinoma inform clinical practice. (r2library.com)
  • The agency asked the implant manufacturers to limit sales of the devices to women who needed reconstruction of a breast and agreed to participate in a clinical trial. (baltimoresun.com)
  • His technique led to the development of Targaprimir-96 and multiple other disease-modifying compounds, some of which are now moving toward clinical development. (scripps.edu)
  • Benign lymphoreticulosis (cat scratch disease, CSD) may have a clinical course that varies from the most common lymphadenitis localized in the site of inoculation, preceded by the typical "primary lesion," to a context of severe systemic involvement. (hindawi.com)
  • We report a case of CSD of the breast in a 59-year-old woman, analyzing the clinical, histopathological, and instrumental appearance and also performing a literature review. (hindawi.com)
  • During the clinical and instrumental investigations, it may appear as a solitary intraglandular mass mimicking inflammatory breast cancer. (hindawi.com)
  • Clinical breast examination is a simple and inexpensive method of detecting breast cancer especially in women who do not have access to mammography. (medindia.net)
  • Accelerated partial breast irradiation (APBI) was shown to be just as effective and safe as whole breast irradiation (WBI), according to the results of a randomized phase III clinical trial conducted in Italy. (cancernetwork.com)
  • Results from a continuing clinical trial in benign breast disease indicate that danazol may induce progesterone receptors and that this effect persists after treatment. (bmj.com)
  • WEDNESDAY, Dec. 9, 2015 (HealthDay News) -- A pair of drugs already on the market appear to reduce the recurrence of breast cancer in women who've already undergone treatment, two new clinical trials show. (health.com)
  • The study was funded by a grant from Specified Nonprofit Corporation-Advanced Clinical Research Organization and other donors to the Japan Breast Cancer Research Group. (health.com)
  • Locally advanced breast cancer refers to clinical stage 3 disease. (thefreelibrary.com)
  • For the purposes of this article 'locally advanced breast cancer' refers to clinical stage 3 disease which may include involvement of supraclavicular nodes (Table I). The postoperative treatment of T1--2 tumours which are found to be pathologically stage 3 due to 4 or more nodes being involved with cancer, will be covered elsewhere. (thefreelibrary.com)
  • Thus, the reviews will not only discuss recent discoveries but will also reflect on their impact in breast cancer research or clinical management. (iospress.com)
  • The outlook for people diagnosed with Paget disease of the breast depends on a variety of factors, including the presence or absence of invasive cancer in the affected breast and, if invasive cancer is present, whether or not it has spread to nearby lymph nodes . (medicinenet.com)
  • These breast tumors are either ductal carcinoma in situ or invasive breast cancer . (medicinenet.com)
  • Usually, Paget's disease occurs alongside another type of cancer - usually ductal carcinoma in situ (DCIS) or invasive breast cancer - elsewhere in the breast. (medicalnewstoday.com)
  • In 90% of these cases, invasive breast cancer is present. (medicalnewstoday.com)
  • Most women with Paget disease also have invasive ductal carcinoma or ductal carcinoma in situ (DCIS). (cancer.ca)
  • The best way to treat invasive breast cancer is to nip it in the bud. (forbes.com)
  • The result is a Gail score, which estimates the risk of developing invasive breast cancer in the next 5 years. (breastcancer.org)
  • The eligibility requirements included age ⩽ 60 years and histological confirmation of metastatic or recurrent invasive breast cancer that had responded either completely or partially to standard-dose chemotherapy. (nature.com)
  • It is important for pathologists, radiologists, and oncologists to recognize benign lesions, both to distinguish them from in situ and invasive breast cancer and to assess a patient's risk of developing breast cancer, so that the most appropriate treatment modality for each case can be established. (health.am)
  • She has a strong interest in female imaging with expertise in all imaging modalities and imaging-guided minimal invasive breast interventions. (springer.com)
  • She is Deputy Editor of European Radiology, a member and past President of the executive board of the Swiss Society of Radiology as well as member of the core team (scientific advisor) and Course Organizer of the MIBB (minimal invasive breast biopsies) working Group of the Swiss Society of Senology. (springer.com)
  • Twenty-five patients have developed invasive breast cancer, yielding a relative risk (RR) of 4.1 (95% confidence interval [CI] = 2.5-5.7). (uni-bonn.de)
  • Paget J. On disease of the mammary areola preceding cancer of the mammary gland. (springer.com)
  • Kanitakis J. Mammary and extramammary Paget's disease. (springer.com)
  • Lloyd J, Flanagan AM. Mammary and extramammary Paget's disease. (springer.com)
  • Underlying pathology in mammary Paget's disease. (springer.com)
  • Pigmented mammary Paget's disease in a man. (springer.com)
  • Underdevelopment of the breast (hypoplasia), when congenital, is usually associated with genetic disorders, such as ulnar-mammary syndrome, Poland's syndrome, Turner's syndrome, and congenital adrenal hyperplasia. (health.am)
  • Other terms that may be used to describe the condition include 'cystic disease,' 'chronic cystic mastitis,' or 'mammary dysplasia. (imaginis.com)
  • Mastitis is a common cause of tenderness, swelling and pain in breast, owing to inflammation in the mammary gland, Breast infection may occur in some cases. (medindia.net)
  • The majority of women with hereditary breast and ovarian cancer have a mutated form of the BRCA1 or BRCA2 genes, which normally suppress the growth of breast and ovarian tumours. (scienceblog.com)
  • You have close relatives who have had breast or ovarian cancer. (healthline.com)
  • Because of these findings, a structured screening program for breast cancer in this high-risk group has been set up in Germany, making use of existing structures put in place by the German Consortium for Hereditary Breast and Ovarian Cancer (Deutsches Konsortium für familiären Brust- und Eierstockkrebs). (eurekalert.org)
  • Scientists have linked the mutation of a protein associated with a specific gene to breast and ovarian cancer. (nurse.com)
  • It also protects against pregnancy, breast cancer and ovarian cancer. (pediatriconcall.com)
  • The study, led by principal investigator Professor Diana Eccles, recorded patients' personal characteristics, tumour characteristics, treatment and family history of breast/ovarian cancer over a 15-year period. (newswise.com)
  • Paget disease of the breast is a form of breast cancer that affects the skin of the nipple . (medicinenet.com)
  • Paget disease of the breast is a rare type of cancer involving the skin of the nipple and, usually, the darker circle of skin around it, known as the areola . (medicinenet.com)
  • Paget disease of the breast is named after the 19th century British doctor Sir James Paget, who, in 1874, noted a relationship between changes in the nipple and breast cancer . (medicinenet.com)
  • Breast discharge is the spontaneous flow of fluid from the nipple at any time other than during nursing. (medicinenet.com)
  • Paget's disease of the breast or nipple refers to breast changes that can indicate that cancer cells are forming in or around the nipple. (medicalnewstoday.com)
  • The latter, unlike Paget's disease, usually affects the areola first and then the nipple. (medicalnewstoday.com)
  • Paget's disease moves from the nipple and out to the areola. (medicalnewstoday.com)
  • One theory is that a person already has cancer of the breast, and some cancer cells migrate through the milk ducts to the surface of the nipple. (medicalnewstoday.com)
  • El Harroudi T, Tijami F, Otmany A, Jalil A. Paget disease of the male nipple. (springer.com)
  • Ucar AE, Korukluoglu B, Ergul E, Aydin R, Kusdemir A. Bilateral Paget's disease of the male nipple: first report. (springer.com)
  • Bilateral Paget's disease of the nipple in a male. (springer.com)
  • Paget's disease in an adolescent arising in a supernumerary nipple. (springer.com)
  • Peschos D, Tsanou E, Dallas P, Charalabopoulos K, Kanaris C, Batistatou A. Mucinous breast carcinoma presenting as Paget's disease of the nipple in a man: a case report. (springer.com)
  • It develops as a rash or other skin changes on the nipple, usually on only one breast. (cancer.ca)
  • In breast-conserving surgery, the nipple and areola are removed. (healthline.com)
  • In these conditions, cells in the ducts (the pipes that drain the milk out to the nipple) or lobules (the parts of the breast that make milk) are growing faster than normal, but the cells look normal. (breastcancer.org)
  • They usually have a nipple and areola and a separate duct system from that of the normal breast. (health.am)
  • Women presenting with nipple discharge account for 5% of all new referrals to specialist breast clinics. (gponline.com)
  • Also called fibrocystic condition, fibrocystic change or cystic mastitis, fibrocystic breast disease is more a characteristic of the breast than a disease. (healthcentral.com)
  • Fibrocystic breast disease, also known as cystic mastitis or fibroadenoma, is not only common, but also worrying. (healthy.net)
  • Fibrocystic Disease (FCD) ;Also known as chronic cystic mastitis. (healthy.net)
  • The relationship between menstrual cycle patterns and the risk of breast disease was evaluated using data from a hospital-based case-control study of 288 women with benign breast disease (203 chronic cystic diseases and 85 benign tumours), 317 with breast cancer and 602 age-matched controls with a spectrum of acute conditions unrelated to any of the established or potential risk factors for breast disease. (nih.gov)
  • The incidence among women aged 50 approaches two per 1000 women per year, and the disease is the single commonest cause of death among women aged 40-50, accounting for about a fifth of all deaths in this age group. (bmj.com)
  • Age The incidence of breast cancer increases with age, doubling about every 10 years until the menopause, when the rate of increase slows dramatically. (bmj.com)
  • Compared with lung cancer, the incidence of breast cancer is higher at younger ages. (bmj.com)
  • Age adjusted incidence and mortality for breast cancer varies by at least a factor of seven between countries. (bmj.com)
  • Adherence to a number of ideal heart health behaviors or factors from the American Heart Association's' Life's Simple 7 is associated with a trend towards a lower incidence of breast cancer. (news-medical.net)
  • Among breast benign diseases, fibroadenoma is the commonest that can occur in women of any age, with a peak incidence in the second and third decades of life [ 12 ]. (hindawi.com)
  • Fibrocystic disease of the breast is the next common whose incidence increases with increasing age [ 11 ]. (hindawi.com)
  • The exact prevalence and incidence of Paget's disease of the breast in the general population isn't known. (healthline.com)
  • The incidence figures for secondary breast cancer are based on long-term observation of 590 female patients in the German-Austrian pediatric treatment trials dating back to the years 1978 to 1995. (eurekalert.org)
  • The association with disease incidence, pattern and histology will be examined. (clinicaltrials.gov)
  • Effects of danazol on incidence of progesterone and oestrogen receptors in benign breast disease. (bmj.com)
  • Risks for breast cancer incidence and mortality were calculated by comparison with expected rates for a general female population matched by age and race. (uni-bonn.de)
  • However, greater alcohol consumption earlier in life (ages 18-22 years) was associated with higher proliferative BBD rates, suggesting that timing of exposure may be relevant to disease incidence. (aacrjournals.org)
  • Some studies indicate that ingestion of methylxanthine- containing substances (e.g. coffee, tea, cola and chocolates), and smoking cigarettes are associated with a higher incidence and greater extent of fibrocystic breast disease. (rxmed.com)
  • But there remains the possibility that treatment regimens for the first breast cancer, including chemotherapy and radiation, might also play a part. (washingtonpost.com)
  • Some small studies suggest that administering common chemotherapy agents in new ways may reduce heart disease risks. (news-medical.net)
  • Doxorubicin is a chemotherapy drug used in breast cancer therapy that can lead to the damage of heart cells. (news-medical.net)
  • A similar two-fold increase in heart failure was observed when mice with a mutated BRCA1 or BRAC2 gene were treated with doxorubicin, one of the most common chemotherapy drugs for patients with breast cancer. (scienceblog.com)
  • The American Heart Association issued a stark warning Thursday for women with breast cancer: Lifesaving therapies like chemotherapy and radiation can cause heart failure and other serious cardiac problems, sometimes years after treatment," it said in the Post . (forbes.com)
  • For decades, doctors have known that radiation, chemotherapy and other cancer drugs, including Herceptin and hormonal agents, can cause or raise a woman's risk for heart disease. (forbes.com)
  • Twelve patients with metastatic breast carcinoma who had stable disease after standard-dose chemotherapy and six who had a partial response underwent allogeneic transplantation. (nature.com)
  • We conclude that among patients with chemotherapy-sensitive metastatic breast cancer, a fraction will achieve a durable complete response after SCT with a reduced-intensity conditioning regimen. (nature.com)
  • In addition to improvements in chemotherapy, radiation, hormone manipulation, and surgery, immunotherapy has emerged as an effective adjunct for the treatment of breast cancer. (nih.gov)
  • The chemotherapy drug capecitabine (Afinitor) seems to reduce by nearly a third the risk of breast cancer recurrence if women receive the drug following surgery to remove their cancer, researchers were to report Wednesday at the 2015 San Antonio Breast Cancer Symposium. (health.com)
  • For the capecitabine study, Japanese researchers enrolled 910 patients who had HER2-negative breast cancer that did not fully respond to chemotherapy prior to surgery. (health.com)
  • Some have suspected that these patients have breast cancer that is somehow resistant to chemotherapy, and that chemo following surgery might not do them any good, said study author Dr. Masakazu Toi, a professor at Kyoto University Hospital in Japan and founder and senior director of the Japan Breast Cancer Research Group. (health.com)
  • In inflammatory disease preoperative chemotherapy is standard. (thefreelibrary.com)
  • Advantages of giving chemotherapy preoperatively include 'downstaging' (although actual stage grouping always remains the same), which will allow surgery in initially inoperable cases or may even allow breast-conserving therapy. (thefreelibrary.com)
  • Certain tumours may be suitable for breast-conserving surgery after chemotherapy. (thefreelibrary.com)
  • More than 3.8 million breast cancer survivors live in the United States, and in about 10% of breast cancer patients, chemotherapy and radiation can damage the heart. (news9.com)
  • metastatic disease remains the underlying cause of death in the majority of patients with breast cancer who succumb to their disease. (nih.gov)
  • In metastatic disease with bone involvement, bisphosphonates prevent or delay skeletal-related events and can improve pain control. (medworm.com)
  • The good news is that some treatments can extend the lives of some women with metastatic disease, by keeping metastatic breast cancer from advancing, at least for a period of time. (bcaction.org)
  • In general, according to the study, women diagnosed with breast cancer in one breast have three to four times the risk of developing a new cancer in the other breast. (washingtonpost.com)
  • A research team from Egypt and the U.S. studied more than 750,000 women diagnosed with breast cancer in the U.S. between 2000 and 2015. (auntminnie.com)
  • This research won't affect women diagnosed with breast cancer today. (asiaone.com)
  • In this context, the push to view breast cancer as a chronic disease seems to be an effort by the cancer establishment to convince the public that we can manage it successfully, and therefore we need not be concerned by the fact that there are still millions of women diagnosed with breast cancer every year. (bcaction.org)
  • The team is currently developing an affordable test for use in hospitals and investigating better personalized treatment options for breast cancer patients based on their findings. (forbes.com)
  • The reported findings have potentially important implications for treatment, because breast cancer in young women is often aggressive and diagnosed at an advanced stage, meaning the prognosis for these patients is often poor. (redorbit.com)
  • The findings show that breast cancer arising at a young age seems to be associated with age-related biological processes, which appear to be independent of other prognostic factors that are commonly used by oncologists. (redorbit.com)
  • Our findings suggest that individuals who are at risk of breast cancer may also be at a previously unrecognized risk of heart disease," Dr. Verma said. (scienceblog.com)
  • Association of BRCA mutation types, imaging features, and pathologic findings in patients with breast cancer with BRCA1 and BRCA2 mutations. (springer.com)
  • Women with hyperthyroidism appear to have a slight but statistically significant increase (9%) in their risk of developing breast cancer, according to the results of a large, population-based study 1 that echoed similar recent findings. (endocrineweb.com)
  • But based on these preliminary findings, we would recommend, that patients with hyperthyroidism should be more aware of the increased risk of breast cancer and have regular follow up for breast cancer screening. (endocrineweb.com)
  • The term "benign breast diseases" encompasses a heterogeneous group of lesions that may present a wide range of symptoms or may be detected as incidental microscopic findings. (health.am)
  • The findings of the randomized study (S6-03) were presented at the 2014 San Antonio Breast Cancer Symposium, held Dec. 6-9, by Kerin Adelson, M.D., assistant professor of medical oncology at Yale Cancer Center and chief quality officer at Smilow Cancer Hospital at Yale-New Haven. (eurekalert.org)
  • Carlos Caldas, who co-led the study at CRUK's Cambridge Research Institute and the University of Cambridge said the findings mean breast cancer should now be seen as an "umbrella term" for a larger number of diseases. (asiaone.com)
  • Harpal Kumar, CRUK's chief executive, said the new findings would help oncologists make far more precise diagnoses for each breast cancer patient - "and that will enable us to make sure that we really target the right treatment to the right woman. (asiaone.com)
  • Our findings indicate a link between select types of benign breast lesions and the later development of breast cancer," says Lynn Hartmann, M.D., Mayo Clinic oncologist and lead investigator of the study. (emaxhealth.com)
  • Dr. Hartmann and her co-investigators were heartened to find convincing evidence that women with the most common, non-proliferative forms of benign findings had no increased risk of developing breast cancer -- as long as they did not have a strong family history of breast cancer. (emaxhealth.com)
  • The functions of BRCA1 in the brain remain to be fully elucidated, but our findings suggest that it may play an important role in supporting critical brain functions in both health and disease," senior author Lennart Mucke, MD, said in the release. (nurse.com)
  • Our findings confirm that the radiation exposure associated with left-breast cancer radiotherapy is associated with a generally small, increased risk of heart disease later in life. (medindia.net)
  • These findings suggest that in some women with benign breast disease who have been treated with danazol changes occur that may have long term benefit. (bmj.com)
  • The findings reported in the March 14 2010 issue of Cancer Causes and Control suggest that eating a diet full of fiber and nuts at young ages may help women reduce their risk for breast cancer. (emaxhealth.com)
  • We were not especially surprised by the findings, given the pink ribbon is one of the most widely recognized symbols in the United States and may lead to the perception that it (breast cancer) causes more deaths," she says. (self.com)
  • ACR Practice Parameter for the Performance of a Breast Ultrasound Examination. (springer.com)
  • Carpentier B, Hayward J, Strachowski L. Enhancing your acoustics: ultrasound image optimization of breast lesions. (springer.com)
  • Reassessment and follow-up results of BI-RADS category 3 lesions detected on screening breast ultrasound. (springer.com)
  • The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. (springer.com)
  • On MRI, the lesion shows thin marginal spiculature and an early marked increase in the signal after contrast with a peak at the second minute, marking itself compatible with focality type 4 BIRADS (BIRADS was developed by the American College of Radiologists as a standard of comparison for rating mammograms and breast ultrasound images. (hindawi.com)
  • The authors estimate that 19% of the girls treated with radiotherapy for Hodgkin's disease develop secondary breast cancer within 30 years as a result of that therapy. (eurekalert.org)
  • The results were presented by the study's principal investigator, Lorenzo Livi, MD, of the radiotherapy-oncology unit at Florence University Hospital in Florence, Italy, at the 2014 San Antonio Breast Cancer Symposium (SABCS), held December 9-13 in San Antonio, Texas. (cancernetwork.com)
  • Accelerated partial breast irradiation using intensity modulated radiotherapy versus whole breast irradiation: 5-year survival results of a phase 3 randomized trial. (cancernetwork.com)
  • Atypical hyperplasia is associated with a fivefold increase in breast cancer risk and is found in an estimated 4 to 10 percent of women with lumpy breasts. (healthcentral.com)
  • While lumpy breasts and discomfort are common in people with fibrocystic breast disease, it is essential to know when to see a doctor. (medicalnewstoday.com)
  • Fibrocystic breast disease is a common way to describe painful, lumpy breasts. (umm.edu)
  • Hormones made in the ovaries may make a woman's breasts feel swollen, lumpy, or painful before or during menstruation each month. (umm.edu)
  • Heart Disease and Saturated Fat: Do the Dietary Guidelines Have It All Wrong? (medhelp.org)
  • Can Mental Stress Lead to Heart Disease? (medhelp.org)
  • Can depression and anxiety cause heart disease? (medhelp.org)
  • And heart disease is the number one cause of death for women in the United States. (healthline.com)
  • It can have a negative impact on lipid profile, which can lead to heart disease. (healthline.com)
  • Aside from treatment, breast cancer and heart disease share some risk factors. (healthline.com)
  • For some women, hormone replacement therapy can raise the risks of both breast cancer and heart disease. (healthline.com)
  • The statement is an overview of what we currently know about risk factors common to both heart disease and breast cancer, the potential heart damage from some breast cancer treatments, and suggested strategies to prevent or minimize the damage. (news-medical.net)
  • Any patient who is going to undergo breast cancer treatment, whether they have heart disease at the beginning or not, should be aware of the potential effects of the treatments on their heart," said Laxmi Mehta, M.D., chair of the writing group for the new scientific statement. (news-medical.net)
  • Heart disease and breast cancer share a number of risk factors, including advanced age, poor diet, family history, physical inactivity and tobacco use. (news-medical.net)
  • However, during and after the treatment of breast cancer, having optimal control of heart disease risk factors is important, because older breast cancer survivors are more likely to die of heart disease than breast cancer," Dr. Mehta said. (news-medical.net)
  • A study published by the American Heart Association says people who have had breast cancer may be at a higher risk for heart disease. (msn.com)
  • But for those who survived, the most common cause of death after 10 years was heart disease, followed by Alzheimer's disease. (auntminnie.com)
  • Common root for breast cancer, heart disease? (scienceblog.com)
  • Women who are at risk for breast cancer may also be at greater risk for heart disease, new research has found. (scienceblog.com)
  • More importantly, we now understand that breast cancer and heart disease - the two leading causes of death for Canadian women - have a common biological basis, a common soil. (scienceblog.com)
  • Knowing that the BRCA1/2 gene is essential to DNA repair may lead to future treatments for anyone with heart disease, a leading cause of death worldwide. (scienceblog.com)
  • Women who carry this mutated gene now know they may also be at a higher risk for developing heart disease in addition to the risk of developing cancer. (scienceblog.com)
  • Heart disease and breast cancer share common risk factors such as age, sedentary lifestyle and smoking. (news-medical.net)
  • The new scientific statement comes after the release of a compilation of prevalence data and shared risk factors for heart disease and breast cancer, as well as the cardiotoxic effects of cancer therapy. (news-medical.net)
  • It highlights the need to prevent and treat heart disease in patients with breast cancer and emphasises the importance of cardiologists and oncologists working together to optimise the health of cancer patients. (news-medical.net)
  • However, heart disease prior to, during or after cancer treatment can impact outcomes. (news-medical.net)
  • We need to be successful in treating both cancer and heart disease. (news-medical.net)
  • Wanting to avoid heart disease is one reason why I exercise on most days and try to keep a healthy diet. (forbes.com)
  • Never mind the implicit competition about what's worse or a more concerning disease for women: cancer vs. heart disease. (forbes.com)
  • To live to be 65 years old, when a woman's risk of dying from heart disease overwhelms the other, she has to live to reach age 65! (forbes.com)
  • Breast cancer patients who take drugs called aromatase inhibitors after surgery face an increased risk of developing heart disease, according to new research. (livescience.com)
  • Earlier work had suggested a link between AIs and heart disease, but the new study included data from more patients and a longer follow-up period, said researcher Dr. Eitan Amir, an oncologist at Princess Margaret Hospital in Toronto. (livescience.com)
  • Longer follow-ups are necessary to study side effects such as heart disease, which can build slowly and take a long time to become apparent. (livescience.com)
  • Researchers at Columbia University Medical Center in New York have found that women who undergo radiation therapy as part of treatment for early stage breast cancer have a slightly increased risk of heart disease. (medindia.net)
  • Writing in the report, published in the JAMA Internal Medicine, the researchers said that depending on a woman's overall susceptibility to heart disease and how the radiation has been delivered, the risk could be anywhere between 0.05 percent to 3.5 percent. (medindia.net)
  • Women who already have an increased risk of heart disease and who receive radiation therapy on their left breast when lying on their back have the greatest risk of heart disease. (medindia.net)
  • An Indian origin surgeon has suggested that women who are at risk for breast cancer may also be at greater risk for heart disease. (mid-day.com)
  • Apparently, heart disease is in the same boat: lifestyle changes are crucial and, in many cases, have been able to control the disease. (bcaction.org)
  • Breastfed babies have lower risk of obesity, cancer, coronary heart disease, inflammatory bowel disease and Diabetes mellitus. (pediatriconcall.com)
  • The 40-year-old had heart disease, the No. 1 cause of death for breast cancer survivors and women overall. (news9.com)
  • How do we prevent heart disease? (news9.com)
  • Breast cancer survivors could be at risk of heart disease years to even a decade after completion of treatment, Moslehi said. (news9.com)
  • They should also speak to them about how to recognize symptoms of heart disease and take preventive measures to lower their risk. (news9.com)
  • But there may be an unintended consequence to the effectiveness of the campaign: The actual leading cause of death in women-heart disease-is getting less play. (self.com)
  • Women are much more likely than men to have 'atypical' symptoms of heart disease, which can make it challenging to know when there's an issue," Andy Barnett, M.D., medical director of Legacy Health-GoHealth Urgent Care, tells SELF. (self.com)
  • While breast cancer is getting a top spot in health perception nationwide, women are neglecting to realize the dangers of heart disease. (self.com)
  • They decided to look at perception of risk, and asked about 600 women aged 35 to 49 about breast cancer risk versus heart disease risk. (self.com)
  • The researchers found that minority women and those with lower education levels were significantly more likely to believe that breast cancer causes more deaths among women than heart disease, according to lead researcher Julie Kapp, M.P.H, Ph.D., associate professor at the University of Missouri School of Medicine. (self.com)
  • African Americans are also at higher risk of heart disease. (self.com)
  • Heart disease-the number one killer of all Americans, female and male-has its own awareness campaign, of course. (self.com)
  • While breast cancer awareness is, of course, vitally important, the perception of lower risk for heart disease could lead many women to see their hearts as less in need of attention. (self.com)
  • A lot of people expect to see physical symptoms of heart disease but that is not always the case ," he says. (self.com)
  • PubMed and China National Knowledge Infrastructure (CNKI) databases were searched up to February 8, 2018 for observational studies examining the association between periodontal disease and breast cancer. (frontiersin.org)
  • A new study has identified that breast cancer can be several genetically distinct diseases, each with a different risk of coming back after treatment. (forbes.com)
  • New research published in the journal Nature shows that breast cancer is 11 genetically distinct diseases, and each has a different prognosis and chance of coming back after treatment. (forbes.com)
  • Today the treatment of breast diseases is largely predicated on the results of randomized prospective trials. (springer.com)
  • Finally, all chapters in the book are thoroughly revised and updated to provide readers with current understanding of the biology and treatment of breast cancer. (springer.com)
  • Treatment of Paget disease of the breast typically involves surgery (either breast-conserving surgery or mastectomy ). (medicinenet.com)
  • A new analysis of the data shows that for patients in either treatment arm whose disease took longer to progress, there was a significantly greater delay in the time it took for their health-related quality of life (QoL) to deteriorate compared to patients who had experienced progression earlier. (medscape.com)
  • In PALOMA-2, patients' quality of life was assessed by administering the Functional Assessment of Cancer Therapy-Breast (FACT-B) questionnaire at baseline and on day 1 of cycle 2, 3, and 5 until progression of disease or the end of treatment. (medscape.com)
  • At the time at which data were cut off, patients from each treatment arm were stratified on the basis of disease progression. (medscape.com)
  • They want breast cancer patients to be aware of the potential effects of treatment on the heart. (healthline.com)
  • This should not deter or scare patients from undergoing breast cancer treatment but should allow them to make informed decisions with their doctor on the best cancer treatment for them," Mehta said in a press release. (healthline.com)
  • Radiation therapy is another treatment that can cause coronary artery disease or blockages, according to the paper. (healthline.com)
  • Gilchrist explained that some breast cancer patients develop risk factors such as weight gain, loss of fitness, and high blood pressure during treatment. (healthline.com)
  • Moreover, these patients have a significantly higher risk of relapse independent of stage, histological grade, breast cancer molecular subtypes and treatment received. (redorbit.com)
  • Breast cancer patients may be at an increased risk of cardiovascular diseases including heart failure and may benefit from a treatment approach that weighs the benefits of specific therapies against potential damage to the heart, according to a new scientific statement from the American Heart Association published in its journal Circulation . (news-medical.net)
  • Because of this, the early development of heart failure can signal a need to slow down and/or alter a patient's breast cancer treatment because of the risk for worsening the condition or the development of permanent heart failure. (news-medical.net)
  • Some breast cancer treatment agents, such as anthracyclines, can result in abnormal heart rhythms that in some patients are benign but in others can lead to life-threatening heart rhythms. (news-medical.net)
  • Healthcare providers should monitor a woman's heart health before, during and after breast cancer treatment. (news-medical.net)
  • Fortunately, with the advances in breast cancer treatment, there has been a growing number of survivors. (news-medical.net)
  • If you have Paget disease of the breast, your healthcare team will create a treatment plan just for you. (cancer.ca)
  • up to 30% of women suffer from breast benign diseases and require treatment at some time in their lives. (hindawi.com)
  • Edwards' treatment could involve removal of part or all the breast and the lymph nodes around it. (nypost.com)
  • The American Heart Association (AHA) recently published a statement highlighting the need to monitor cardiovascular health in women receiving treatment for breast cancer. (news-medical.net)
  • Breast cancer treatment usually consists of a combination of therapies. (healthline.com)
  • One potential complication of this type of breast cancer is that symptoms can be easily dismissed or misdiagnosed, delaying treatment. (healthline.com)
  • As a woman in her late fifties who's alive after breast cancer treatment-and glad to be so, here and aging―I know I'm at risk. (forbes.com)
  • As I see it, concern about treatment toxicity is all-the-more reason to find breast cancer early. (forbes.com)
  • The long latency period between initial treatment and eventual recurrence in some patients suggests that a tumour may both alter and respond to the host systemic environment to facilitate and sustain disease progression. (nih.gov)
  • As for the survival benefit, Dr. Weng suggested that "even after they are diagnosed with breast cancer, these women may have been more compliant with treatment and thus have a better survival. (endocrineweb.com)
  • Dr. Maurice M. Black,78, an early champion of alternatives to radical mastectomies in the treatment of breast cancer, died Saturday of liver cancer in New York.An internationally renowned expert in the field of breast disease, he published 250 studies dating to July 1953, when he predicted that "the use of ultra radical surgical attempts to cure breast cancer are not consistent with the biology of the disease. (baltimoresun.com)
  • Amir said a trend among patients taking AIs has become clear: They are less likely than patients taking tamoxifen to see their breast cancer recur after treatment. (livescience.com)
  • The fewest deaths, without breast cancer recurrence ," were seen in patients who took tamoxifen for two or three years after their surgery, then switched to an AI for the rest of their treatment, he said. (livescience.com)
  • Treatment of breast cancer in the adjuvant setting has changed rapidly over the last few years. (nih.gov)
  • The current literature regarding vaccine development for the treatment of breast cancer in the adjuvant setting is also reviewed. (nih.gov)
  • LONDON - Scientists who conducted a major international study into the genetics of breast cancer say they can now classify the disease into 10 subtypes - a finding that points to more accurate, tailored treatment for individual patients in future. (asiaone.com)
  • Drugs such as the generic tamoxifen, and aromatase inhibitors like AstraZeneca's Arimidex or Novartis's Femara, which block oestrogen activity, are already used in targeted treatment for breast cancer patients whose tumors produce large amounts of oestrogen receptor (ER). (asiaone.com)
  • An experimental therapy seems to have eradicated cancer in a patient with metastatic breast cancer who had failed every other treatment. (npr.org)
  • The breast cancer patient helped by the treatment says it transformed her life. (npr.org)
  • A detailed description of the Paget's disease of the breast, characteristic signs and symptoms, detection methods and treatment modalities. (medindia.net)
  • Partial breast [irradiation] certainly will be an effective option for treatment in selected breast cancer patients," Livi told Cancer Network via e-mail. (cancernetwork.com)
  • APBI is an alternative treatment to WBI, used in certain early-stage breast cancer patients who typically have small tumors, clear margins after surgery, and cancer with no involvement of the lymph nodes. (cancernetwork.com)
  • Zero and three patients had new ipsilateral breast cancer in the WBI and APBI treatment arms, respectively ( P = .063). (cancernetwork.com)
  • Contralateral breast cancer occurred in seven and three patients in the WBI and APBI treatment arms, respectively ( P = .31). (cancernetwork.com)
  • Still, Livi emphasized that WBI "will remain a key point of treatment for a large [portion] of breast cancer [patients who] underwent breast-conserving surgery. (cancernetwork.com)
  • This study quantifies the risk of breast cancer following Hodgkin's disease treatment according to age at treatment and type of treatment. (uni-bonn.de)
  • Denosumab (Xgeva) is usually given to women undergoing breast cancer treatment because hormone therapy for their disease can make their bones brittle, explained lead researcher Dr. Michael Gnant, a professor of surgery at the Medical University of Vienna in Austria. (health.com)
  • These patients underwent standard treatment for their breast cancer, and then were randomly assigned post-treatment to take either capecitabine or a placebo. (health.com)
  • Previous studies have shown that denosumab reduces bone fractures by half in women following breast cancer treatment, but researchers suspected that the drug might also improve their chances of remaining cancer-free. (health.com)
  • One thing I find interesting at this moment is that advances in treatment have led the cancer industry to begin to talk of breast cancer as a "chronic disease. (bcaction.org)
  • If metastatic breast cancer is ever to actually become a chronic disease, we will need far more progress in the treatment and improved quality of life for those who take these treatments. (bcaction.org)
  • Mastectomy is usually the mainstay of surgical treatment in stage 3 disease but the extent of surgery thought appropriate may vary from surgeon to surgeon, with some having a more conservative approach and others advocating resection of extensive disease with fascia and muscle and a latissimus dorsi flap. (thefreelibrary.com)
  • Breast cancer treatment puts the heart at risk in several ways. (news9.com)
  • The common breast cancer treatment endoxifen has been shown to cause hot flashes and vaginal atrophy as well as a higher risk of endometrial cancer and stroke, according to a report from the University of Illinois at Chicago. (fiercepharma.com)
  • It is a known treatment for "cyclic mastalgia" and other breast-related issues. (earthclinic.com)
  • Continue reading below for specific remedies and feedback from our wonderful readers reporting the most effective treatment for tender breasts. (earthclinic.com)
  • Newswise - A new study has found that women who are diagnosed with breast cancer and have a family history of the disease face no worse of a prognosis after treatment than other women with breast cancer. (newswise.com)
  • The investigators found that there were no significant differences in cancer recurrence rates after treatment for women with a history of breast cancer in their family versus those without. (newswise.com)
  • Successful treatment for breast cancer is just as likely in young patients with a family history of breast cancer, as in those without a family history," said Professor Cutress. (newswise.com)
  • If the outlook is more optimistic than might be expected for these patients, this will help in planning future preventive surgical options at the time of breast cancer treatment. (newswise.com)
  • Further studies should consider whether breast cancer subtypes and other factors, including differences in treatment regimens, influence longer-term survival in young compared to older women, and white compared to black women, the researchers noted. (prweb.com)
  • A cutting-edge research collaboration is tackling early detection and improved treatment of breast cancer. (vancouverobserver.com)
  • If women on AIs are noticing eye or vision changes (e.g., dry eye), they should speak with their physician about the possibility these changes are a side effect of their breast cancer treatment. (bcaction.org)
  • For this study, the researchers looked at more than 7,000 one-year survivors of breast cancer who had been under the age of 71 when they were diagnosed. (washingtonpost.com)
  • Breast cancer in young women is a biologically unique disease that requires customized management strategies, researchers report at the 4th IMPAKT Breast Cancer Conference, in Brussels, Belgium. (redorbit.com)
  • The researchers also found that a gene called RANKL is highly expressed in young women with breast cancer. (redorbit.com)
  • The researchers included 754,270 U.S. women with breast cancer diagnosed from 2000 through 2015 and retrieved through the Surveillance, Epidemiology, and End Results (SEER) program. (auntminnie.com)
  • I don't subscribe to the Cancer or Disease Olympics theory of allocating resources for patients or researchers or causes. (forbes.com)
  • Researchers have updated the BCSC Risk Calculator to include benign breast disease information to make the tool more accurate. (breastcancer.org)
  • But when the researchers used the updated model that included benign breast disease history, they found that 27.8% of the women had a 5-year risk of breast cancer of 3% or higher. (breastcancer.org)
  • 3 The researchers found that hypothyroidism showed a slightly lower albeit not statistically significant risk for breast cancer. (endocrineweb.com)
  • Now a recent study by California researchers has found that low levels of the same protein, BRCA1, might contribute to Alzheimer's disease. (nurse.com)
  • The researchers suspected defects in DNA repair mechanisms could contribute to cognitive decline in Alzheimer's disease and focused their studies on BRCA1, which plays a key role in repairing DNA. (nurse.com)
  • But for the first time, researchers say that the gene may also play a part in the nerve death that's responsible for Alzheimer's disease. (time.com)
  • Two years later, the researchers found the patients assigned capecitabine had a 31 percent reduced risk of disease recurrence compared with those assigned the placebo. (health.com)
  • Researchers enrolled 3,425 postmenopausal patients with early stage, HR-positive breast cancer and randomly assigned 1,711 to 60 milligrams of injected denosumab once every six months. (health.com)
  • After an average follow-up of four years, patients assigned denosumab had an 18 percent reduced risk of disease recurring compared with those assigned placebo, researchers found. (health.com)
  • THURSDAY, Dec. 24 (HealthDay News) -- An analysis of breast cancer genomes has provided insight into how the human genome is rearranged when the disease strikes, researchers report. (bio-medicine.org)
  • Researchers in Chicago have developed a method by which to deliver a breast cancer-preventing drug through the skin to avoid some of the nasty side effects associated with oral ingestion of the drug. (fiercepharma.com)
  • The researchers now plan to investigate whether certain breast cancer gene variants have any impact on the effectiveness of different anticancer treatments. (newswise.com)
  • In a recent study, researchers from the Cancer Prevention Institute of California (CPIC) found that the biological subtype of breast cancer diagnosed in adolescent and young adult women directly affects their risk of dying from the disease. (prweb.com)
  • The researchers found that adolescent and young adult women diagnosed with the subtype HR-/HER2+ have a 1.6 times greater risk of dying from the disease than women with HR+/HER2- breast cancer, which is the most common type, present in 41 percent of study participants. (prweb.com)
  • In a previous study, CPIC researchers found that women 15 to 39 years of age were more likely to be diagnosed with later stage disease, as well as the subtypes associated with poorer survival than older women, the authors noted. (prweb.com)
  • CPIC researchers obtained data from the California Cancer Registry for 5,331 young women ranging in age from 15 to 39 diagnosed with breast cancer between 2005 and 2009. (prweb.com)
  • For comparison purposes, the researchers also evaluated data from 53,860 women between 40 and 64 years of age who had been diagnosed with breast cancer. (prweb.com)
  • Researchers at the University of Missouri were struck by how recent studies indicated that the U.S. has a disadvantage in women's life expectancy compared to peer countries , despite high rates of health screenings like mammography and breast cancer awareness. (self.com)
  • Routine laboratory tests are not helpful in evaluation of benign breast disease. (rxmed.com)
  • The nodules or cysts can spread throughout the breast, may be located in one general area or simply appear as one or more large cysts. (healthcentral.com)
  • Multiple small cysts and an increasing level of breast pain commonly develop when a woman hits her 30s. (healthcentral.com)
  • Cysts and fatty tumors that aren't cancer are examples of benign breast disease. (breastcancer.org)
  • Very little is known about genetic aspects of fibrocystic breast disease, but family history of cysts is common. (rxmed.com)
  • In this review, the most frequently seen benign lesions of the breast are summarized as developmental abnormalities, inflammatory lesions, fibrocystic changes, stromal lesions, and neoplasms. (health.am)
  • This conventional approach has been found to be particularly effective in inflammatory breast cancer. (thefreelibrary.com)
  • Periodontal disease, a complex polymicrobial inflammatory disease, is a public health burden and is partially responsible for tooth loss. (frontiersin.org)
  • Nonalcoholic fatty liver disease (NAFLD) is one of the more common chronic liver diseases worldwide. (elsevier.com)
  • I was diagnosed with chronic Lyme disease in June 2015. (celiac.com)
  • A chronic disease is a disease that is long lasting or recurrent. (bcaction.org)
  • The term chronic describes the course of the disease, or its rate of onset and development. (bcaction.org)
  • By this definition, metastatic breast cancer is recurrent, not chronic. (bcaction.org)
  • If a "chronic" disease is one that the public believes can be successfully managed by the person who is ill-without serious side effects from the treatments-clearly metastatic breast cancer is not a chronic disease. (bcaction.org)
  • clearly metastatic breast cancer is not a chronic disease. (bcaction.org)
  • Breast cancer is also sometimes referred to as a chronic disease, because the risk of recurrence never completely disappears. (bcaction.org)
  • Urging the public to accept the notion of early breast cancer as a chronic disease undermines the demand for true breast cancer prevention. (bcaction.org)
  • We all need to move beyond accepting the notion of breast cancer as a chronic disease if we are to have any hope of truly ending the epidemic. (bcaction.org)
  • 15 ), reported an increased risk of breast cancer among patients with chronic periodontitis [Hazard ratio (HR) = 1.23, 95% confidence interval (CI) = 1.11-1.36] although no such observation was found amongst subjects who underwent gingivectomy or periodontal flap operation (HR = 1.17, 95%CI = 0.86-1.58). (frontiersin.org)
  • Symptoms of fibrocystic breast disease can include tenderness and swelling. (medicalnewstoday.com)
  • Some women only experience mild breast swelling during menstruation, while others experience constant breast tenderness. (imaginis.com)
  • Breast tenderness. (wikipedia.org)
  • Symptoms and signs of Paget disease of the breast can be similar to those of benign skin conditions and can include itching , redness, thickening, or crusting of the skin. (medicinenet.com)
  • Most of the time, people with Paget disease of the breast also have one or more tumors inside the same breast. (medicinenet.com)
  • Paget disease of the breast may be misdiagnosed at first because its early symptoms are similar to those caused by some benign skin conditions . (medicinenet.com)
  • What is Paget disease of the breast? (medicinenet.com)
  • Several other diseases are named after Sir James Paget, including Paget disease of bone and extramammary Paget disease, which includes Paget disease of the vulva and Paget disease of the penis. (medicinenet.com)
  • These other diseases are not related to Paget disease of the breast. (medicinenet.com)
  • This fact sheet discusses only Paget disease of the breast. (medicinenet.com)
  • Who gets Paget disease of the breast? (medicinenet.com)
  • Paget disease of the breast occurs in both women and men, but most cases occur in women. (medicinenet.com)
  • Approximately 1 to 4 percent of all cases of breast cancer also involve Paget disease of the breast. (medicinenet.com)
  • Doctors do not fully understand what causes Paget disease of the breast. (medicinenet.com)
  • Paget disease of the breast is a rare type of breast cancer. (cancer.ca)
  • Paget disease of the breast is more common in women over the age of 50. (cancer.ca)
  • This would explain why Paget disease of the breast and tumors inside the same breast are almost always found together ( 1 , 3 ). (cancer.gov)
  • Moreover, it may be possible for Paget disease of the breast and tumors inside the same breast to develop independently ( 1 ). (cancer.gov)
  • What are the symptoms of Paget disease of the breast? (cancer.gov)
  • The symptoms of Paget disease of the breast are often mistaken for those of some benign skin conditions, such as dermatitis or eczema ( 1 - 3 ). (cancer.gov)
  • Because the early symptoms of Paget disease of the breast may suggest a benign skin condition, and because the disease is rare, it may be misdiagnosed at first. (cancer.gov)
  • People with Paget disease of the breast have often had symptoms for several months before being correctly diagnosed. (cancer.gov)
  • How is Paget disease of the breast diagnosed? (cancer.gov)
  • How is Paget disease of the breast treated? (cancer.gov)
  • For many years, mastectomy , with or without the removal of lymph nodes under the arm on the same side of chest (known as axillary lymph node dissection), was regarded as the standard surgery for Paget disease of the breast ( 3 , 4 ). (cancer.gov)
  • This type of surgery was done because patients with Paget disease of the breast were almost always found to have one or more tumors inside the same breast. (cancer.gov)
  • Among these disorders, Poland's syndrome is the congenital anomaly that has been reported to be associated with breast cancer most often. (health.am)
  • Treatments for breast cancer have improved dramatically in recent years, but unfortunately for some women, their breast cancer returns and spreads, becoming incurable. (forbes.com)
  • There are no specific treatments for fibrocystic breast disease, other than those to minimize discomfort. (healthcentral.com)
  • Some treatments for breast cancer can harm your heart. (healthline.com)
  • During cancer treatments, patients should pay attention not only to their breast health, but also to their general health, including their heart, said Dr. Mehta, who is director of the Women's Cardiovascular Health Program and an associate professor of medicine at The Ohio State University in Columbus, Ohio. (news-medical.net)
  • Other treatments, such as radiation, can affect the heart arteries and cause the development of coronary artery disease or blockages. (news-medical.net)
  • Find out more about these treatments for breast cancer . (cancer.ca)
  • Furthermore, some treatments used in patients with breast cancer can have a negative impact on cardiovascular health. (news-medical.net)
  • With earlier detection and improved treatments, long-term survival among women who develop breast cancer is good. (news-medical.net)
  • Paget's disease of the breast is usually found on only one breast, and it won't respond to topical treatments. (healthline.com)
  • A bunch of recent articles stress that breast cancer treatments can damage the heart. (forbes.com)
  • We now know that breast cancer is not one disease but is multiple different diseases, which may behave in unique ways and respond to different treatments. (vancouverobserver.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • Saving Lives, Protecting People Centers for Disease Control and Prevention. (cdc.gov)
  • Services (HHS) and the Director of the Centers for Disease Control and Prevention (CDC) regarding the formative research, development, implementation, and evaluation of evidence-based activities designed to prevent breast cancer (particularly among those at heightened risk). (cdc.gov)
  • The study was supported in part by the State of California Department of Public Health, the National Cancer Institute and the Centers for Disease Control and Prevention. (prweb.com)
  • Symptoms of fibrocystic breast disease may come and go during the menstrual cycle. (medicalnewstoday.com)
  • A large study found that women who took estrogen HRT after menopause were about twice as likely to develop benign (not cancerous) breast disease as women who didn't take estrogen HRT. (breastcancer.org)
  • Fibrocystic breast condition is a common, non-cancerous condition that affects more than 50% of women at some point in their lives. (imaginis.com)
  • Benign Breast Disease Anatomical Chart -9781587796746 : Benign Breast Disease Anatomical Chart Pub Date: June 2003 Product Type: Print Author/s: Anatomical Chart Company This chart defines benign (non-cancerous) breast disease and illustrates the most common types, such as fibrocystic breast disease, benign breast tumors, and breast infection and inflammation. (egeneralmedical.com)
  • In addition to an increased risk of breast cancer, the results reported here suggest that using estrogen HRT also can increase a woman's risk of benign breast disease. (breastcancer.org)
  • More importantly, we see that many of the same things that improve heart health (healthy diet, healthy weight, exercise, not smoking) can also reduce a woman's risk for breast cancer. (news-medical.net)
  • Bromocriptine reduces prolactin release and suppresses breast milk production after pregnancy . (healthcentral.com)
  • Although it can vary, the pain or discomfort is usually located in the undersides of the breasts or in the upper areas, when the majority of milk glands are. (medicalnewstoday.com)
  • It is the most common type of breast cancer, which can spread from the milk ducts to other parts of the breast or beyond if not treated promptly. (nypost.com)
  • During each menstrual cycle, normal hormonal stimulation causes the breasts’ milk glands and ducts to enlarge, and in turn, the breasts may retain water. (imaginis.com)
  • Joining us to explain how breast milk could be used to fight these diseases is Dr. Rana Alissa who is a pediatrician with UF Health Jacksonville. (news4jax.com)
  • We searched the literature in PubMed ( www.ncbi.nlm.nih.gov/pubmed ), EMBASE ( www.elsevier.com/online-tools/embase ), and Google Scholar ( http://scholar.google.com/ ) for all published articles until January 2013, using the terms "breast-feeding" and "Chagas," "breastfeeding" and " Trypanosoma cruzi ," "milk" and "Chagas," and "milk" and " Trypanosoma cruzi . (cdc.gov)
  • Breast milk is the best food for the babies as it meets all the requirements. (pediatriconcall.com)
  • There is enough evidence to suggest Breast milk offers short term and long term benefits both in developing and developed world. (pediatriconcall.com)
  • Breast milk contains all the nutrients which are required for the normal growth and development. (pediatriconcall.com)
  • All babies can easily digest and absorb Breast milk. (pediatriconcall.com)
  • Breast milk is 70% whey and 30% casein. (pediatriconcall.com)
  • Breast milk fat is rich in polyunsaturated fatty acid and is the major energy source. (pediatriconcall.com)
  • How to express Breast Milk? (pediatriconcall.com)
  • Mother can either express the milk by hand or using a breast pump (Manual or electrical). (pediatriconcall.com)
  • The vast majority of the lesions that occur in the breast are benign. (health.am)
  • Because the majority of benign lesions are not associated with an increased risk for subsequent breast cancer, unnecessary surgical procedures should be avoided. (health.am)
  • Mesenchymal Lesions of the Breast: What Radiologists Need to Know. (harvard.edu)
  • However, for proliferative and atypical types, the opposite was true, and these lesions pointed to an increased risk of a future breast cancer, even when the family history of breast cancer was negative. (emaxhealth.com)
  • All benign breast samples were evaluated by a breast pathologist unaware of initial diagnoses or patient outcomes and assigned to one of three categories of benign breast lesions, non-proliferative, proliferative and atypical. (emaxhealth.com)
  • This information was used to link the risk of subsequent development of breast cancer to specific types of lesions. (emaxhealth.com)
  • A lifelong irregular menstrual pattern [defined as frequent occurrence of menstrual-like episodes of bleeding less than 21 or more than 35 days apart) was negatively associated with the risk of benign breast lesions (relative risk, RR = 0.6, with 95% confidence interval = 0.4-1.0) and of breast cancer (RR = 0.4, with 95% confidence interval = 0.3-0.8]. (nih.gov)
  • Barth D. Bilateral Paget's disease of the breast-case report of long-time misdiagnosed tumors with underlying ductal carcinomas and review of the literature. (springer.com)
  • Elia was told she had breast cancer, ductal carcinoma. (emofree.com)
  • Women receiving post-lumpectomy radiation before the age of 45 had a 1.5-fold increased risk of contralateral breast cancer when compared with women who had undergone post-mastectomy radiation, according to the study. (washingtonpost.com)
  • If you do have breast tumors, removing the whole breast (mastectomy) may be recommended. (healthline.com)
  • New chapters have been added on pathology of in situ carcinomas, prophylactic contralateral mastectomy, implications of obesity in breast cancer, and an overview of survivorship issues. (r2library.com)
  • Commenting on the recently published study, which he was not involved in, Prof Bryan Hennessy, from Beaumont Hospital in Dublin, said: "Young women with breast cancer tend to have a poorer prognosis. (redorbit.com)
  • While waiting for the results of NSABP B-39, partial breast irradiation represents an attractive alternative for early breast cancer patients at low risk of recurrence," said Livi. (cancernetwork.com)
  • In addition, an osteoporosis medication called denosumab appears to reduce recurrence risk by 18 percent in women who have HR-positive breast cancer, a second study reports. (health.com)
  • Sometimes for as long as they live, even though they may well live a long life and die without a breast cancer recurrence. (bcaction.org)
  • It results in a reduction of locoregional recurrence of about two-thirds and also has been shown to improve survival in high-risk and node-positive disease, (6-9) although a consistent survival benefit in stage 3 disease has not been shown. (thefreelibrary.com)
  • Regular breast self-exams, annual exams by your doctor, and routine mammograms also are very important to detect both benign breast disease and breast cancer early. (breastcancer.org)
  • I started doing breast self-exams at age 40, just as I was told to do. (nytimes.com)
  • Also, a drug called dexrazoxane was recently approved for patients with metastatic breast cancer who are getting high doses of doxorubicin. (healthline.com)
  • In addition, a drug called dexrazoxane that could reduce cell damage has recently been approved for patients with metastatic breast cancer who receive high doses of doxorubicin. (news-medical.net)
  • The combination should be studied in other populations of patients, Adelson added, including those who are newly diagnosed with metastatic breast cancer and those who have already progressed on fulvestrant. (eurekalert.org)
  • This study will collect information on the height and weight of women who participated in a 1998 study in Triana, Alabama, on the risk of breast cancer and benign breast disease in relation to environmental exposure to the pesticide DDT and similar chemicals. (clinicaltrials.gov)
  • This study is evaluating how ruxolitinib affects premalignant breast cells. (clinicaltrials.gov)
  • Reporting in the journal Nature Communications , Lennart Mucke and his colleagues at the Gladstone institute of Neurological Disease have found that the BRCA1 gene not only affects the way cells can grow by promoting cancer, but can also interfere with nerve cells' ability to repair their DNA. (time.com)
  • Chagas disease is a zoonotic infection caused by the parasite Trypanosoma cruzi, which affects an estimated 8 -11 million people globally. (medworm.com)
  • Carcinoma of the male breast accounts for less than 1% of all malignancies in men and 0.2% of male cancer deaths. (springer.com)
  • Paget's disease of the ectopic breast with an underlying intraductal carcinoma: report of a case. (springer.com)
  • Lobular carcinoma in situ (LCIS): LCIS is abnormal cell growth in the breast lobules. (breastcancer.org)
  • While the word "carcinoma" is in its name, LCIS isn't a true breast cancer. (breastcancer.org)
  • Ideal for any clinician seeing patients with breast disease, especially carcinoma of the breast, This full color 5th Edition of the authoritative text in the field is designed to foster the understanding necessary to provide optimal patient care. (r2library.com)