Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
Aquaporin 4 is the major water-selective channel in the CENTRAL NERVOUS SYSTEM of mammals.
Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening.
Fluids composed mainly of water found within the body.
Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states.
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
The ratio of the density of a material to the density of some standard material, such as water or air, at a specified temperature.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
An azo dye used in blood volume and cardiac output measurement by the dye dilution method. It is very soluble, strongly bound to plasma albumin, and disappears very slowly.
Pressure within the cranial cavity. It is influenced by brain mass, the circulatory system, CSF dynamics, and skull rigidity.
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
The circulation of blood through the BLOOD VESSELS of the BRAIN.
Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.
Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
A subfamily of the Muridae consisting of several genera including Gerbillus, Rhombomys, Tatera, Meriones, and Psammomys.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
Increased pressure within the cranial vault. This may result from several conditions, including HYDROCEPHALUS; BRAIN EDEMA; intracranial masses; severe systemic HYPERTENSION; PSEUDOTUMOR CEREBRI; and other disorders.
The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
An excessive amount of fluid in the cornea due to damage of the epithelium or endothelium causing decreased visual acuity.
Abnormal fluid retention by the body due to impaired cardiac function or heart failure. It is usually characterized by increase in venous and capillary pressure, and swollen legs when standing. It is different from the generalized edema caused by renal dysfunction (NEPHROTIC SYNDROME).
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
Compounds that increase urine volume by increasing the amount of osmotically active solute in the urine. Osmotic diuretics also increase the osmolarity of plasma.
A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)
A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A condition resulting from the excessive retention of water with sodium depletion.
A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
Elements of limited time intervals, contributing to particular results or situations.
A class of porins that allow the passage of WATER and other small molecules across CELL MEMBRANES.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
Elevated level of AMMONIA in the blood. It is a sign of defective CATABOLISM of AMINO ACIDS or ammonia to UREA.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
An acute disease of young pigs that is usually associated with weaning. It is characterized clinically by paresis and subcutaneous edema.
The part of the brain that connects the CEREBRAL HEMISPHERES with the SPINAL CORD. It consists of the MESENCEPHALON; PONS; and MEDULLA OBLONGATA.
Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.
A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
The arterial blood vessels supplying the CEREBRUM.
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
Embolism or thrombosis involving blood vessels which supply intracranial structures. Emboli may originate from extracranial or intracranial sources. Thrombosis may occur in arterial or venous structures.
Restoration of blood supply to tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. It is primarily a procedure for treating infarction or other ischemia, by enabling viable ischemic tissue to recover, thus limiting further necrosis. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing REPERFUSION INJURY.
Veins draining the cerebrum.
Enzymes that catalyze the degradation of collagen by acting on the peptide bonds.
A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)
Large endothelium-lined venous channels situated between the two layers of DURA MATER, the endosteal and the meningeal layers. They are devoid of valves and are parts of the venous system of dura mater. Major cranial sinuses include a postero-superior group (such as superior sagittal, inferior sagittal, straight, transverse, and occipital) and an antero-inferior group (such as cavernous, petrosal, and basilar plexus).
Abnormal accumulation of fluid in tissues of any part of the LARYNX, commonly associated with laryngeal injuries and allergic reactions.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Assessment of sensory and motor responses and reflexes that is used to determine impairment of the nervous system.
A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
Surgery performed on the nervous system or its parts.
Forceful administration into the peritoneal cavity of liquid medication, nutrient, or other fluid through a hollow needle piercing the abdominal wall.
A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.

Transforming growth factor-alpha acting at the epidermal growth factor receptor reduces infarct volume after permanent middle cerebral artery occlusion in rats. (1/1215)

Transforming growth factor-alpha (TGF-alpha) is a ligand for the epidermal growth factor (EGF) receptor (EGFR), and is more abundant than EGF in the brain. The authors studied whether administration of exogenous TGF-alpha into the brain can protect neurons against ischemia in a model of permanent middle cerebral artery (MCA) occlusion in the rat, and whether any effect of TGF-alpha was mediated by EGFR by administering 4,5-dianilinophthalimide (DAPH), a protein-tyrosine kinase inhibitor with high selectivity for EGFR. Rats received either TGF-alpha (10 or 25 ng), DAPH (100 ng), DAPH plus TGF-alpha (25 ng), or vehicle in the ipsilateral first ventricle. Drugs were administered twice: 30 minutes before and 30 minutes after MCA occlusion, and infarct volume was evaluated 24 hours later. Transforming growth factor-alpha at the dose of 25 ng caused a statistically significant reduction of infarct volume (60%) in relation to ischemic rats administered vehicle. This reduction was no longer seen when TGF-alpha was administered in combination with DAPH. The present results show that TGF-alpha can protect neurons from ischemic damage, and that this effect is mediated by EGFR. It is suggested that activation of EGFR-mediated intracellular signalling pathways contributes to the survival of neural cells susceptible to ischemic injury.  (+info)

Computerised axial tomography in patients with severe migraine: a preliminary report. (2/1215)

Patients suffering from severe migraine, usually for many years, have been examined by the EMI scanner between attacks. Judged by criteria validated originally by comparison with pneumoencephalography, about half of the patients showed evidence of cerebral atrophy. Perhaps of more significance than generalised atrophy was the frequency of areas of focal atrophy and of evidence of infarction.  (+info)

Two similar cases of encephalopathy, possibly a reversible posterior leukoencephalopathy syndrome: serial findings of magnetic resonance imaging, SPECT and angiography. (3/1215)

Two young women who had encephalopathy that resembled reversible posterior leukoencephalopathy syndrome are presented. The brain magnetic resonance imaging (MRI) of these patients exhibited similar T2-high signal lesions, mostly in the white matter of the posterior hemispheres. Xe-SPECT during the patients' symptomatic period showed hypoperfusion in the corresponding areas, and angiography demonstrated irregular narrowing of the posterior cerebral artery. Clinical manifestations subsided soon after treatment, and the abnormal radiological findings also were almost completely resolved. Thus, we concluded that transient hypoperfusion followed by ischemia and cytotoxic edema might have had a pivotal role in these cases.  (+info)

Significance of acute cerebral swelling in patients with sylvian hematoma due to ruptured middle cerebral artery aneurysm, and its management. (4/1215)

A retrospective study of 75 patients treated surgically for ruptured middle cerebral artery (MCA) aneurysm within 48 hours evaluated clinical grade at admission, secondary development and management of cerebral swelling associated with space-occupying hematoma, cerebral infarction caused by vasospasm, development of hydrocephalus, and clinical outcome. Clinical grade at admission was significantly better in patients without than in those with hematoma (p < 0.01). Twenty-seven patients with sylvian hematoma caused by ruptured MCA aneurysm often developed ipsilateral cerebral swelling in the early period after subarachnoid hemorrhage. Seventeen of these patients developed serious cerebral swelling and received barbiturate therapy. Nine of these 17 patients had good outcome, but six patients died of cerebral swelling. The incidence of hydrocephalus was significantly higher in patients with than in those without hematoma (p < 0.01). The incidence of infarction was more pronounced in patients with sylvian hematoma. Clinical outcome was significantly better in patients without than in those with sylvian hematoma (p < 0.01). Development of cerebral swelling in patients with sylvian hematoma due to ruptured MCA aneurysm has a significant effect on outcome, and improvements in management are required.  (+info)

Cerebral blood flow in the monkey after focal cryogenic injury. (5/1215)

A focal cryogenic lesion was made in the left superior frontal gyrus of the anesthetized macaque brain. Cerebral blood flow (CBF) was determined by the hydrogen clearance technique before and during the 4 hours following trauma. Local CBF in tissue adjacent to the lesion increased in the first half hour after the lesion was made and then decreased during the ensuing 3 1/2 hours. Local CBF in the contralateral superior frontal gyrus, as well as total CBF and oxygen consumption, were unchanged by cryogenic trauma. The spread of vasogenic edema into uninjured tissue probably accounts for the observed decrease in local CBF. This experimental model may assist in discovering therapy to alter favorably the spatial and temporal profile of pathologic CBF changes in tissue surrounding an acute lesion of the brain.  (+info)

Abrupt exacerbation of acute subdural hematoma mimicking benign acute epidural hematoma on computed tomography--case report. (6/1215)

A 75-year-old male was hit by a car, when riding a bicycle. The diagnosis of acute epidural hematoma was made based on computed tomography (CT) findings of lentiform hematoma in the left temporal region. On admission he had only moderate occipitalgia and amnesia of the accident, so conservative therapy was administered. Thirty-three hours later, he suddenly developed severe headache, vomiting, and anisocoria just after a positional change. CT revealed typical acute subdural hematoma (ASDH), which was confirmed by emergent decompressive craniectomy. He was vegetative postoperatively and died of pneumonia one month later. Emergent surgical exploration is recommended for this type of ASDH even if the symptoms are mild due to aged atrophic brain.  (+info)

Epilepsy after two different neurosurgical approaches to the treatment of ruptured intracranial aneurysm. (7/1215)

One-hundred-and-fifty-two patients who underwent surgery for intracranial aneurysm were studied to determine the incidence of postoperative epilepsy in relation to the site of the aneurysm and the type of surgical approach. The overall incidence of epilepsy was 22%. Of the 116 patients treated by the intracranial approach 27.5% developed epilepsy, in contrast with only 5% of the 36 patients who had carotid artery ligation in the neck. Epilepsy occurred most frequently (35%) with middle cerebral artery aneurysms, especially if moderate or severe operative trauma was sustained and there was postoperative dysphasia.  (+info)

Glial and capillary density of the pontine white matter in swelling and atrophy. (8/1215)

A total of 48 autopsied brains were morphometrically examined for the relation between pontine geometry and structural parameters. In each case, the numerical density of neuroglial cells Nv(G) and the linear density of capillary network Lv(C) of the pontine white matter were determined stereologically from the counts of glial nuclear profiles and capillary transections per constant area of a histological section with a constant thickness. It was revealed that in general the glial numerical density increased with advancing atrophy and decreased with increasing swelling, whereas the capillary linear density remained fairly constant especially in the advanced stage of brain swelling. Further analysis of this relation using a model of pontine geometry has made it clear that the total capillary length in the swollen white matter increases probably at the expense of the capillary caliber as swelling advances. The changes in the ratio Lv(C)/Nv(G) under pathological conditions are emphasized and possible utility of classifying stages of acute brain swelling from a viewpoint of microvascular dimension is suggested.  (+info)

The word "edema" comes from the Greek word "oidema", meaning swelling.

There are several types of edema, including:

1. Pitting edema: This type of edema occurs when the fluid accumulates in the tissues and leaves a pit or depression when it is pressed. It is commonly seen in the skin of the lower legs and feet.
2. Non-pitting edema: This type of edema does not leave a pit or depression when pressed. It is often seen in the face, hands, and arms.
3. Cytedema: This type of edema is caused by an accumulation of fluid in the tissues of the limbs, particularly in the hands and feet.
4. Edema nervorum: This type of edema affects the nerves and can cause pain, numbness, and tingling in the affected area.
5. Lymphedema: This is a condition where the lymphatic system is unable to properly drain fluid from the body, leading to swelling in the arms or legs.

Edema can be diagnosed through physical examination, medical history, and diagnostic tests such as imaging studies and blood tests. Treatment options for edema depend on the underlying cause, but may include medications, lifestyle changes, and compression garments. In some cases, surgery or other interventions may be necessary to remove excess fluid or tissue.

There are several different types of brain injuries that can occur, including:

1. Concussions: A concussion is a type of mild traumatic brain injury that occurs when the brain is jolted or shaken, often due to a blow to the head.
2. Contusions: A contusion is a bruise on the brain that can occur when the brain is struck by an object, such as during a car accident.
3. Coup-contrecoup injuries: This type of injury occurs when the brain is injured as a result of the force of the body striking another object, such as during a fall.
4. Penetrating injuries: A penetrating injury occurs when an object pierces the brain, such as during a gunshot wound or stab injury.
5. Blast injuries: This type of injury occurs when the brain is exposed to a sudden and explosive force, such as during a bombing.

The symptoms of brain injuries can vary depending on the severity of the injury and the location of the damage in the brain. Some common symptoms include:

* Headaches
* Dizziness or loss of balance
* Confusion or disorientation
* Memory loss or difficulty with concentration
* Slurred speech or difficulty with communication
* Vision problems, such as blurred vision or double vision
* Sleep disturbances
* Mood changes, such as irritability or depression
* Personality changes
* Difficulty with coordination and balance

In some cases, brain injuries can be treated with medication, physical therapy, and other forms of rehabilitation. However, in more severe cases, the damage may be permanent and long-lasting. It is important to seek medical attention immediately if symptoms persist or worsen over time.

Symptoms of pulmonary edema may include:

* Shortness of breath (dyspnea)
* Coughing up frothy sputum
* Chest pain or tightness
* Fatigue
* Confusion or disorientation

Pulmonary edema can be diagnosed through physical examination, chest x-rays, electrocardiogram (ECG), and blood tests. Treatment options include oxygen therapy, diuretics, and medications to manage underlying conditions such as heart failure or sepsis. In severe cases, hospitalization may be necessary to provide mechanical ventilation.

Prevention measures for pulmonary edema include managing underlying medical conditions, avoiding exposure to pollutants and allergens, and seeking prompt medical attention if symptoms persist or worsen over time.

In summary, pulmonary edema is a serious condition that can impair lung function and lead to shortness of breath, chest pain, and other respiratory symptoms. Prompt diagnosis and treatment are essential to prevent complications and improve outcomes for patients with this condition.

The term ischemia refers to the reduction of blood flow, and it is often used interchangeably with the term stroke. However, not all strokes are caused by ischemia, as some can be caused by other factors such as bleeding in the brain. Ischemic stroke accounts for about 87% of all strokes.

There are different types of brain ischemia, including:

1. Cerebral ischemia: This refers to the reduction of blood flow to the cerebrum, which is the largest part of the brain and responsible for higher cognitive functions such as thought, emotion, and voluntary movement.
2. Cerebellar ischemia: This refers to the reduction of blood flow to the cerebellum, which is responsible for coordinating and regulating movement, balance, and posture.
3. Brainstem ischemia: This refers to the reduction of blood flow to the brainstem, which is responsible for controlling many of the body's automatic functions such as breathing, heart rate, and blood pressure.
4. Territorial ischemia: This refers to the reduction of blood flow to a specific area of the brain, often caused by a blockage in a blood vessel.
5. Global ischemia: This refers to the reduction of blood flow to the entire brain, which can be caused by a cardiac arrest or other systemic conditions.

The symptoms of brain ischemia can vary depending on the location and severity of the condition, but may include:

1. Weakness or paralysis of the face, arm, or leg on one side of the body
2. Difficulty speaking or understanding speech
3. Sudden vision loss or double vision
4. Dizziness or loss of balance
5. Confusion or difficulty with memory
6. Seizures
7. Slurred speech or inability to speak
8. Numbness or tingling sensations in the face, arm, or leg
9. Vision changes, such as blurred vision or loss of peripheral vision
10. Difficulty with coordination and balance.

It is important to seek medical attention immediately if you experience any of these symptoms, as brain ischemia can cause permanent damage or death if left untreated.

Brain neoplasms can arise from various types of cells in the brain, including glial cells (such as astrocytes and oligodendrocytes), neurons, and vascular tissues. The symptoms of brain neoplasms vary depending on their size, location, and type, but may include headaches, seizures, weakness or numbness in the limbs, and changes in personality or cognitive function.

There are several different types of brain neoplasms, including:

1. Meningiomas: These are benign tumors that arise from the meninges, the thin layers of tissue that cover the brain and spinal cord.
2. Gliomas: These are malignant tumors that arise from glial cells in the brain. The most common type of glioma is a glioblastoma, which is aggressive and hard to treat.
3. Pineal parenchymal tumors: These are rare tumors that arise in the pineal gland, a small endocrine gland in the brain.
4. Craniopharyngiomas: These are benign tumors that arise from the epithelial cells of the pituitary gland and the hypothalamus.
5. Medulloblastomas: These are malignant tumors that arise in the cerebellum, specifically in the medulla oblongata. They are most common in children.
6. Acoustic neurinomas: These are benign tumors that arise on the nerve that connects the inner ear to the brain.
7. Oligodendrogliomas: These are malignant tumors that arise from oligodendrocytes, the cells that produce the fatty substance called myelin that insulates nerve fibers.
8. Lymphomas: These are cancers of the immune system that can arise in the brain and spinal cord. The most common type of lymphoma in the CNS is primary central nervous system (CNS) lymphoma, which is usually a type of B-cell non-Hodgkin lymphoma.
9. Metastatic tumors: These are tumors that have spread to the brain from another part of the body. The most common types of metastatic tumors in the CNS are breast cancer, lung cancer, and melanoma.

These are just a few examples of the many types of brain and spinal cord tumors that can occur. Each type of tumor has its own unique characteristics, such as its location, size, growth rate, and biological behavior. These factors can help doctors determine the best course of treatment for each patient.

Infarction Middle Cerebral Artery (MCA) is a type of ischemic stroke that occurs when there is an obstruction in the middle cerebral artery. This artery supplies blood to the temporal lobe of the brain, which controls many important functions such as memory, language, and spatial reasoning. When this artery becomes blocked or ruptured, it can cause a lack of blood supply to the affected areas resulting in tissue death (infarction).

The symptoms of an MCA infarction can vary depending on the location and severity of the blockage. Some common symptoms include weakness or paralysis on one side of the body, difficulty with speech and language, memory loss, confusion, vision problems, and difficulty with coordination and balance. Patients may also experience sudden severe headache, nausea, vomiting, and fever.

The diagnosis of MCA infarction is based on a combination of clinical examination, imaging studies such as CT or MRI scans, and laboratory tests. Imaging studies can help to identify the location and severity of the blockage, while laboratory tests may be used to rule out other conditions that may cause similar symptoms.

Treatment for MCA infarction depends on the underlying cause of the blockage or rupture. In some cases, medications such as thrombolytics may be given to dissolve blood clots and restore blood flow to the affected areas. Surgery may also be required to remove any blockages or repair damaged blood vessels. Other interventions such as endovascular procedures or brain bypass surgery may also be used to restore blood flow.

In summary, middle cerebral artery infarction is a type of stroke that occurs when the blood supply to the brain is blocked or interrupted, leading to damage to the brain tissue. It can cause a range of symptoms including weakness or paralysis on one side of the body, difficulty with speech and language, memory loss, confusion, vision problems, and difficulty with coordination and balance. The diagnosis is based on a combination of clinical examination, imaging studies, and laboratory tests. Treatment options include medications, surgery, endovascular procedures, or brain bypass surgery.

Symptoms of cerebral hemorrhage may include sudden severe headache, confusion, seizures, weakness or numbness in the face or limbs, and loss of consciousness. The condition is diagnosed through a combination of physical examination, imaging tests such as CT or MRI scans, and laboratory tests to determine the cause of the bleeding.

Treatment for cerebral hemorrhage depends on the location and severity of the bleeding, as well as the underlying cause. Medications may be used to control symptoms such as high blood pressure or seizures, while surgery may be necessary to repair the ruptured blood vessel or relieve pressure on the brain. In some cases, the condition may be fatal, and immediate medical attention is essential to prevent long-term damage or death.

Some of the most common complications associated with cerebral hemorrhage include:

1. Rebleeding: There is a risk of rebleeding after the initial hemorrhage, which can lead to further brain damage and increased risk of death.
2. Hydrocephalus: Excess cerebrospinal fluid can accumulate in the brain, leading to increased intracranial pressure and potentially life-threatening complications.
3. Brain edema: Swelling of the brain tissue can occur due to the bleeding, leading to increased intracranial pressure and potentially life-threatening complications.
4. Seizures: Cerebral hemorrhage can cause seizures, which can be a sign of a more severe injury.
5. Cognitive and motor deficits: Depending on the location and severity of the bleeding, cerebral hemorrhage can result in long-term cognitive and motor deficits.
6. Vision loss: Cerebral hemorrhage can cause vision loss or blindness due to damage to the visual cortex.
7. Communication difficulties: Cerebral hemorrhage can cause difficulty with speech and language processing, leading to communication difficulties.
8. Behavioral changes: Depending on the location and severity of the bleeding, cerebral hemorrhage can result in behavioral changes, such as irritability, agitation, or apathy.
9. Infection: Cerebral hemorrhage can increase the risk of infection, particularly if the hemorrhage is caused by a ruptured aneurysm or arteriovenous malformation (AVM).
10. Death: Cerebral hemorrhage can be fatal, particularly if the bleeding is severe or if there are underlying medical conditions that compromise the patient's ability to tolerate the injury.

Types: There are several types of brain infarction, including:

1. Cerebral infarction: This type of infarction occurs when there is a blockage or obstruction in the blood vessels that supply the cerebrum, which is the largest part of the brain.
2. Cerebellar infarction: This type of infarction occurs when there is a blockage or obstruction in the blood vessels that supply the cerebellum, which is located at the base of the brain.
3. Brain stem infarction: This type of infarction occurs when there is a blockage or obstruction in the blood vessels that supply the brain stem, which is the part of the brain that controls vital functions such as breathing, heart rate, and blood pressure.

Symptoms: The symptoms of brain infarction can vary depending on the location and size of the affected area, but common symptoms include:

1. Sudden weakness or numbness in the face, arm, or leg
2. Sudden confusion or trouble speaking or understanding speech
3. Sudden difficulty seeing or blindness
4. Sudden difficulty walking or loss of balance
5. Sudden severe headache
6. Difficulty with coordination and movement
7. Slurred speech
8. Vision changes
9. Seizures

Diagnosis: Brain infarction is typically diagnosed using a combination of physical examination, medical history, and imaging tests such as CT or MRI scans. Other diagnostic tests may include blood tests to check for signs of infection or blood clotting abnormalities, and an electroencephalogram (EEG) to measure the electrical activity of the brain.

Treatment: The treatment of brain infarction depends on the underlying cause, but common treatments include:

1. Medications: To control symptoms such as high blood pressure, seizures, and swelling in the brain.
2. Endovascular therapy: A minimally invasive procedure to open or remove blockages in the blood vessels.
3. Surgery: To relieve pressure on the brain or repair damaged blood vessels.
4. Rehabilitation: To help regain lost function and improve quality of life.

Prognosis: The prognosis for brain infarction depends on the location and size of the affected area, as well as the promptness and effectiveness of treatment. In general, the earlier treatment is received, the better the outcome. However, some individuals may experience long-term or permanent disability, or even death.

1) They share similarities with humans: Many animal species share similar biological and physiological characteristics with humans, making them useful for studying human diseases. For example, mice and rats are often used to study diseases such as diabetes, heart disease, and cancer because they have similar metabolic and cardiovascular systems to humans.

2) They can be genetically manipulated: Animal disease models can be genetically engineered to develop specific diseases or to model human genetic disorders. This allows researchers to study the progression of the disease and test potential treatments in a controlled environment.

3) They can be used to test drugs and therapies: Before new drugs or therapies are tested in humans, they are often first tested in animal models of disease. This allows researchers to assess the safety and efficacy of the treatment before moving on to human clinical trials.

4) They can provide insights into disease mechanisms: Studying disease models in animals can provide valuable insights into the underlying mechanisms of a particular disease. This information can then be used to develop new treatments or improve existing ones.

5) Reduces the need for human testing: Using animal disease models reduces the need for human testing, which can be time-consuming, expensive, and ethically challenging. However, it is important to note that animal models are not perfect substitutes for human subjects, and results obtained from animal studies may not always translate to humans.

6) They can be used to study infectious diseases: Animal disease models can be used to study infectious diseases such as HIV, TB, and malaria. These models allow researchers to understand how the disease is transmitted, how it progresses, and how it responds to treatment.

7) They can be used to study complex diseases: Animal disease models can be used to study complex diseases such as cancer, diabetes, and heart disease. These models allow researchers to understand the underlying mechanisms of the disease and test potential treatments.

8) They are cost-effective: Animal disease models are often less expensive than human clinical trials, making them a cost-effective way to conduct research.

9) They can be used to study drug delivery: Animal disease models can be used to study drug delivery and pharmacokinetics, which is important for developing new drugs and drug delivery systems.

10) They can be used to study aging: Animal disease models can be used to study the aging process and age-related diseases such as Alzheimer's and Parkinson's. This allows researchers to understand how aging contributes to disease and develop potential treatments.

Symptoms of intracranial hypertension can include headache, nausea and vomiting, confusion, seizures, and loss of consciousness. Treatment options depend on the underlying cause, but may include medications to reduce pressure, draining excess CSF, or surgery to relieve obstruction.

Intracranial hypertension can be life-threatening if left untreated, as it can lead to permanent brain damage and even death. Therefore, prompt medical attention is essential for proper diagnosis and management of this condition.

Causes:

1. Viral hepatitis (hepatitis A, B, or C)
2. Overdose of medications or supplements
3. Toxic substances (e.g., alcohol, drugs, or chemicals)
4. Sepsis or other infections that spread to the liver
5. Certain autoimmune disorders (e.g., hemochromatosis, Wilson's disease)
6. Cancer that has metastasized to the liver
7. Blood vessel blockage or clotting in the liver
8. Lack of blood flow to the liver

Symptoms:

1. Jaundice (yellowing of skin and eyes)
2. Nausea and vomiting
3. Abdominal swelling and discomfort
4. Fatigue, weakness, and loss of appetite
5. Confusion or altered mental state
6. Seizures or coma
7. Pale or clay-colored stools
8. Dark urine

Diagnosis:

1. Physical examination and medical history
2. Laboratory tests (e.g., liver function tests, blood tests, imaging studies)
3. Biopsy of the liver tissue (to rule out other liver diseases)

Treatment:

1. Supportive care (fluids, nutrition, and medication to manage symptoms)
2. Addressing underlying causes (e.g., stopping alcohol or drug use, treating infections)
3. Transjugular intrahepatic portosystemic shunt (TIPS), a procedure that creates a new pathway for blood to flow through the liver
4. Liver transplantation (in severe cases where other treatments have failed)

Prognosis:
The prognosis for acute liver failure depends on the underlying cause of the condition and the severity of the liver damage. In general, the earlier the diagnosis and treatment, the better the outcome. However, acute liver failure can be a life-threatening condition, and the mortality rate is high, especially in cases where there is severe liver damage or no available donor liver for transplantation.

Some common symptoms of corneal edema include:

* Blurred vision
* Haziness or clouding of the cornea
* Increased sensitivity to light
* Redness or discharge in the eye
* Pain or discomfort in the eye

Corneal edema can be diagnosed through a comprehensive eye exam, which may include a visual acuity test, dilated eye exam, and imaging tests such as cornea scans or ultrasound. Treatment for corneal edema depends on the underlying cause and may involve antibiotics, anti-inflammatory medications, or other therapies to reduce swelling and promote healing. In some cases, surgery may be necessary to remove scar tissue or improve drainage of fluid from the eye.

If left untreated, corneal edema can lead to more serious complications such as corneal ulcers or vision loss. Therefore, it is important to seek medical attention if you experience any symptoms of corneal edema to prevent any further damage and ensure proper treatment.

A condition characterized by swelling of the heart and surrounding tissues due to an accumulation of fluid. This can occur as a result of various conditions such as heart failure, coronary artery disease, or cardiomyopathy. The swelling can lead to symptoms such as shortness of breath, fatigue, and difficulty exercising. Treatment options include diuretics, ACE inhibitors, and other medications to manage the underlying condition causing the edema.

Example sentence: "The patient was diagnosed with cardiac edema and started on a regimen of diuretics and ACE inhibitors to help reduce the swelling and improve their symptoms."

Cerebral infarction can result in a range of symptoms, including sudden weakness or numbness in the face, arm, or leg on one side of the body, difficulty speaking or understanding speech, sudden vision loss, dizziness, and confusion. Depending on the location and severity of the infarction, it can lead to long-term disability or even death.

There are several types of cerebral infarction, including:

1. Ischemic stroke: This is the most common type of cerebral infarction, accounting for around 87% of all cases. It occurs when a blood clot blocks the flow of blood to the brain, leading to cell death and tissue damage.
2. Hemorrhagic stroke: This type of cerebral infarction occurs when a blood vessel in the brain ruptures, leading to bleeding and cell death.
3. Lacunar infarction: This type of cerebral infarction affects the deep structures of the brain, particularly the basal ganglia, and is often caused by small blockages or stenosis (narrowing) in the blood vessels.
4. Territorial infarction: This type of cerebral infarction occurs when there is a complete blockage of a blood vessel that supplies a specific area of the brain, leading to cell death and tissue damage in that area.

Diagnosis of cerebral infarction typically involves a combination of physical examination, medical history, and imaging tests such as CT or MRI scans. Treatment options vary depending on the cause and location of the infarction, but may include medication to dissolve blood clots, surgery to remove blockages, or supportive care to manage symptoms and prevent complications.

Meningioma can occur in various locations within the brain, including the cerebrum, cerebellum, brainstem, and spinal cord. The most common type of meningioma is the meningothelial meningioma, which arises from the arachnoid membrane, one of the three layers of the meninges. Other types of meningioma include the dural-based meningioma, which originates from the dura mater, and the fibrous-cap meningioma, which is characterized by a fibrous cap covering the tumor.

The symptoms of meningioma can vary depending on the location and size of the tumor, but they often include headaches, seizures, weakness or numbness in the arms or legs, and changes in vision, memory, or cognitive function. As the tumor grows, it can compress the brain tissue and cause damage to the surrounding structures, leading to more severe symptoms such as difficulty speaking, walking, or controlling movement.

The diagnosis of meningioma typically involves a combination of imaging studies such as MRI or CT scans, and tissue sampling through biopsy or surgery. Treatment options for meningioma depend on the size, location, and aggressiveness of the tumor, but may include surgery, radiation therapy, and chemotherapy. Overall, the prognosis for meningioma is generally good, with many patients experiencing a good outcome after treatment. However, some types of meningioma can be more aggressive and difficult to treat, and the tumor may recur in some cases.

The symptoms of water intoxication can vary depending on the severity of the condition, but may include:

* Headache
* Nausea and vomiting
* Seizures
* Confusion and disorientation
* Slurred speech
* Weakness or fatigue
* Increased heart rate
* Low blood pressure

In severe cases, water intoxication can cause seizures, coma, and even death.

The diagnosis of water intoxication is based on a combination of symptoms, medical history, and laboratory tests, such as blood tests to measure electrolyte levels. Treatment typically involves cessation of fluid intake, administration of electrolytes, and monitoring of vital signs. In severe cases, hospitalization may be necessary to monitor and treat the condition.

Prevention of water intoxication is key, and this can be achieved by drinking fluids in moderation and avoiding excessive intake during physical activity or in hot weather. It is also important to monitor fluid intake in individuals who are at risk, such as endurance athletes or those with certain medical conditions.

In summary, water intoxication is a serious condition that can occur when a person consumes too much water, leading to an imbalance of electrolytes in the body. It is important to be aware of the symptoms and seek medical attention if they occur, as prompt treatment can help prevent complications and death.

This condition is most commonly seen in people with advanced liver disease, such as cirrhosis or liver cancer. It can also be caused by other conditions that affect the liver, such as hepatitis or portal hypertension.

Symptoms of hepatic encephalopathy can include confusion, disorientation, slurred speech, memory loss, and difficulty with coordination and balance. In severe cases, it can lead to coma or even death.

Diagnosis of hepatic encephalopathy is typically made through a combination of physical examination, medical history, and diagnostic tests such as blood tests and imaging studies. Treatment options include medications to reduce the production of ammonia in the gut, antibiotics to treat any underlying infections, and transjugular intrahepatic portosystemic shunt (TIPS) to improve liver function. In severe cases, a liver transplant may be necessary.

Overall, hepatic encephalopathy is a serious condition that can have significant impact on quality of life and survival in people with advanced liver disease. Early detection and prompt treatment are essential to prevent complications and improve outcomes.

Causes of Hyperammonemia:

1. Liver disease or failure: The liver is responsible for filtering out ammonia, so if it is not functioning properly, ammonia levels can rise.
2. Urea cycle disorders: These are genetic conditions that affect the body's ability to break down protein and produce urea. As a result, ammonia can build up in the bloodstream.
3. Inborn errors of metabolism: Certain inherited disorders can lead to hyperammonemia by affecting the body's ability to process ammonia.
4. Sepsis: Severe infections can cause inflammation in the body, which can lead to hyperammonemia.
5. Kidney disease or failure: If the kidneys are not functioning properly, they may be unable to remove excess ammonia from the bloodstream, leading to hyperammonemia.

Symptoms of Hyperammonemia:

1. Lethargy and confusion
2. Seizures
3. Coma
4. Vomiting
5. Diarrhea
6. Decreased appetite
7. Weight loss
8. Fatigue
9. Headache
10. Nausea and vomiting

Diagnosis of Hyperammonemia:

1. Blood tests: Measurement of ammonia levels in the blood is the most common method used to diagnose hyperammonemia.
2. Urine tests: Measurement of urea levels in the urine can help determine if the body is able to produce and excrete urea normally.
3. Imaging tests: Imaging tests such as CT or MRI scans may be ordered to look for any underlying liver or kidney damage.
4. Genetic testing: If the cause of hyperammonemia is suspected to be a genetic disorder, genetic testing may be ordered to confirm the diagnosis.

Treatment of Hyperammonemia:

1. Dietary changes: A low-protein diet and avoiding high-aminogram foods can help reduce ammonia production in the body.
2. Medications: Medications such as sodium benzoate, sodium phenylbutyrate, and ribavirin may be used to reduce ammonia production or increase urea production.
3. Dialysis: In severe cases of hyperammonemia, dialysis may be necessary to remove excess ammonia from the blood.
4. Liver transplantation: In cases where the cause of hyperammonemia is liver disease, a liver transplant may be necessary.
5. Nutritional support: Providing adequate nutrition and hydration can help support the body's metabolic processes and prevent complications of hyperammonemia.

Complications of Hyperammonemia:

1. Brain damage: Prolonged elevated ammonia levels in the blood can cause brain damage, leading to cognitive impairment, seizures, and coma.
2. Respiratory failure: Severe hyperammonemia can lead to respiratory failure, which can be life-threatening.
3. Cardiac complications: Hyperammonemia can cause cardiac complications such as arrhythmias and heart failure.
4. Kidney damage: Prolonged elevated ammonia levels in the blood can cause kidney damage and failure.
5. Infections: People with hyperammonemia may be more susceptible to infections due to impaired immune function.

In conclusion, hyperammonemia is a serious condition that can have severe consequences if left untreated. It is essential to identify the underlying cause of hyperammonemia and provide appropriate treatment to prevent complications. Early detection and management of hyperammonemia can improve outcomes and reduce the risk of long-term sequelae.

Example sentence: "The patient experienced a transient ischemic attack, which was caused by a temporary blockage in one of the blood vessels in their brain."

Synonyms: TIA, mini-stroke.

Edema disease is caused by a picornavirus and is characterized by fever, lethargy, loss of appetite, and difficulty breathing due to severe inflammation of the respiratory tract. The skin becomes edematous (swollen) and hemorrhages occur under the skin and in internal organs such as the lungs and liver. Death can occur within 24 to 48 hours after the onset of symptoms.

The disease is transmitted through direct contact with infected swine or contaminated fomites, and the virus can survive for several days in the environment. The incubation period is typically 3-7 days, and infected animals may not show any clinical signs until they are heavily infected.

There is no specific treatment or vaccine available for edema disease, and control measures are focused on preventing the spread of the virus through proper sanitation, biosecurity measures, and culling of infected animals. The disease is considered highly contagious and can have a significant impact on swine populations if not controlled promptly.

The symptoms of meningeal neoplasms vary depending on the location, size, and type of tumor. Common symptoms include headaches, seizures, weakness or numbness in the arms or legs, and changes in vision, memory, or behavior. As the tumor grows, it can compress or displaces the brain tissue, leading to increased intracranial pressure and potentially life-threatening complications.

There are several different types of meningeal neoplasms, including:

1. Meningioma: This is the most common type of meningeal neoplasm, accounting for about 75% of all cases. Meningiomas are usually benign and grow slowly, but they can sometimes be malignant.
2. Metastatic tumors: These are tumors that have spread to the meninges from another part of the body, such as the lung or breast.
3. Lymphoma: This is a type of cancer that affects the immune system and can spread to the meninges.
4. Melanotic neuroectodermal tumors (MNTs): These are rare, malignant tumors that usually occur in children and young adults.
5. Hemangiopericytic hyperplasia: This is a rare, benign condition characterized by an overgrowth of blood vessels in the meninges.

The diagnosis of meningeal neoplasms is based on a combination of clinical symptoms, physical examination findings, and imaging studies such as CT or MRI scans. A biopsy may be performed to confirm the diagnosis and determine the type of tumor.

Treatment options for meningeal neoplasms depend on the type, size, and location of the tumor, as well as the patient's overall health. Surgery is often the first line of treatment, and may involve removing as much of the tumor as possible or using a laser to ablate (destroy) the tumor cells. Radiation therapy and chemotherapy may also be used in combination with surgery to treat malignant meningeal neoplasms.

Prognosis for meningeal neoplasms varies depending on the type of tumor and the patient's overall health. In general, early diagnosis and treatment improve the prognosis, while later-stage tumors may have a poorer outcome.

1. Atrial fibrillation (a type of irregular heartbeat)
2. Heart disease or valve problems
3. Blood clots in the legs or lungs
4. Infective endocarditis (an infection of the heart valves)
5. Cancer and its treatment
6. Trauma to the head or neck
7. High blood pressure
8. Atherosclerosis (the buildup of plaque in the arteries)

When a blockage occurs in one of the blood vessels of the brain, it can deprive the brain of oxygen and nutrients, leading to cell death and potentially causing a range of symptoms including:

1. Sudden weakness or numbness in the face, arm, or leg
2. Sudden confusion or trouble speaking or understanding speech
3. Sudden trouble seeing in one or both eyes
4. Sudden severe headache
5. Dizziness or loss of balance
6. Fainting or falling

Intracranial embolism and thrombosis can be diagnosed through a variety of imaging tests, including:

1. Computed tomography (CT) scan
2. Magnetic resonance imaging (MRI)
3. Magnetic resonance angiography (MRA)
4. Cerebral angiography
5. Doppler ultrasound

Treatment options for intracranial embolism and thrombosis depend on the underlying cause of the blockage, but may include:

1. Medications to dissolve blood clots or prevent further clotting
2. Surgery to remove the blockage or repair the affected blood vessel
3. Endovascular procedures, such as angioplasty and stenting, to open up narrowed or blocked blood vessels
4. Supportive care, such as oxygen therapy and pain management, to help manage symptoms and prevent complications.

The symptoms of a brain abscess can vary depending on the location and size of the abscess, but may include:

* Headache
* Fever
* Confusion or disorientation
* Seizures
* Weakness or numbness in the arms or legs
* Vision problems
* Speech difficulties

If a brain abscess is suspected, a doctor will typically perform a physical examination and order imaging tests such as CT or MRI scans to confirm the diagnosis. Treatment usually involves antibiotics to treat the underlying infection, as well as surgery to drain the abscess and remove any infected tissue. In severe cases, hospitalization may be necessary to monitor and treat the patient.

With prompt and appropriate treatment, most people with a brain abscess can recover fully or almost fully, but in some cases, the condition can result in long-term complications such as memory loss, cognitive impairment, or personality changes. In rare instances, a brain abscess can be fatal if not treated promptly and properly.

Brain Edema. San Diego: Academic Press. pp. 315-335. doi:10.1016/b978-0-12-803196-4.00017-5. ISBN 978-0-12-803196-4. Ehmsen J, ...
Brain Edema IX. Acta Neurochirurgica. Supplementum. Vol. 60. pp. 15-9. doi:10.1007/978-3-7091-9334-1_4. ISBN 978-3-7091-9336-5 ... NMDA is an excitatory receptor in the brain, when activated normally the receptor acts as an ion channel and there is an influx ... PCP is well known for its primary action on the NMDA receptor, an ionotropic glutamate receptor, in rats and in rat brain ... Some studies found that, like other NMDA receptor antagonists, PCP can cause a kind of brain damage called Olney's lesions in ...
Brain Edema IX. Acta Neurochirurgica. Supplementum. Vol. 60. pp. 15-9. doi:10.1007/978-3-7091-9334-1_4. ISBN 978-3-7091-9336-5 ... Brain. 128 (Pt 2): 300-7. doi:10.1093/brain/awh354. PMID 15634735. Banks P, Franks NP, Dickinson R (March 2010). "Competitive ... glutamate binding sites in rat brain synaptic membranes". Brain Research. 520 (1): 351-353. doi:10.1016/0006-8993(90)91729-Z. ... "Muscimol prevents NMDA antagonist neurotoxicity by activating GABAA receptors in several brain regions". Brain Research. 993 (1 ...
... cerebral edema (swelling of the brain); changes in the blood flow to the brain; and raised intracranial pressure (the pressure ... Primary and secondary brain injury are ways to classify the injury processes that occur in brain injury. In traumatic brain ... Other factors in secondary damage are breakdown of the blood-brain barrier, edema, ischemia and hypoxia. Ischemia is one of the ... It occurs after a variety of brain injury including subarachnoid hemorrhage, stroke, and traumatic brain injury and involves ...
"Brain - Intramyelinic Edema - Nonneoplastic Lesion Atlas". ntp.niehs.nih.gov. Retrieved 2021-04-13. Wang J, Leone P, Wu G, ... Liu D, Zhu M, Zhang Y, Diao Y (January 2021). "Crossing the blood-brain barrier with AAV vectors". Metabolic Brain Disease. 36 ... pressure and intramyelinic edema in CD patients suggest the existence of an efficient MWP in the brain. The MWP is a membrane ... In human trials, NAA levels in patient's brain and urine was found to drop after one year of treatment. This is coupled with ...
Koizumi, J.; Y. Yoshida; T. Nakazawa; G. Ooneda (1986). "Experimental studies of ischemic brain edema. I: a new experimental ... This approach is useful to study hypoxic ischemia in the developing brain, since newborn rat pups are utilized in this model. ... However, in various settings global ischemia is also relevant, e.g. in global anoxic brain damage due to cardiac arrest. ... After intravenous injection of photosensitive dyes like rose-bengal, the brain is irradiated through the skull via a small hole ...
... insufficient oxygen in the brain); cerebral edema (swelling of the brain); and raised intracranial pressure (the pressure ... When the pressure within the skull rises too high, it can cause brain death or brain herniation, in which parts of the brain ... at the Wayback Machine Wikimedia Commons has media related to Traumatic brain injuries. Brain injury at Curlie The Brain Injury ... A traumatic brain injury (TBI), also known as an intracranial injury, is an injury to the brain caused by an external force. ...
Hypoxia, anoxia can lead to cytotoxic edema through several mechanisms Extracellular brain edema, or vasogenic edema, is caused ... When brain edema types are combined, there is typically a primary form and the edema type and context of the cause must be ... The association of brain edema with increased in hospital risk of death was observed in TBI across all level of severity. Edema ... Mild traumatic brain injury (TBI) represents 70-90% of all reported head injuries. The presence of brain edema on the initial ...
"Brain Edema" or "Critical Care Nursing"). Most of these are accompanied by a short description or definition, links to related ...
Oedem des Hirns, Hydrocephalus, 1878 - Edema of the brain, Hydrocephalus. Anatomie Des Centres Nerveux, 1879 - Anatomy of the ... Huguenin specialized in research of brain and nerve disorders. He contributed treatises on encephalitis, meningitis, et al. to ...
Larsen FS, Wendon J (2002). "Brain edema in liver failure: basic physiologic principles and management". Liver Transpl. 8 (11 ... In ALF, hepatic encephalopathy leads to cerebral edema, coma, brain herniation, and eventually death. Detection of ... Consider a brain computed tomography (CT) scan to rule out other causes of altered or impaired mental status. Stimulation and ... It may vary from subtle deficit in higher brain function (e.g. mood, concentration in grade I) to deep coma (grade IV). ...
This can be thought of as an example of brain edema of the "cytotoxic" type. Despite numerous studies demonstrating the central ... Coma and seizures represent the most advanced stage; cerebral edema (swelling of the brain tissue) leads to death. ... A CT scan of the brain usually shows no abnormality except in stage IV encephalopathy, when brain swelling (cerebral oedema) ... A CT scan of the brain may be required to exclude bleeding in the brain, and if seizure activity is suspected an ...
One of the serious effects of traumatic brain injury includes edema. Animal studies show that progesterone treatment leads to a ... Stein DG (March 2008). "Progesterone exerts neuroprotective effects after brain injury". Brain Research Reviews. 57 (2): 386-97 ... brain stem, thalamus and corpus callosum of the female rat". Brain Research. 125 (2): 313-24. doi:10.1016/0006-8993(77)90624-2 ... Brain Research. Brain Research Reviews. 37 (1-3): 116-32. doi:10.1016/s0165-0173(01)00112-6. PMID 11744080. S2CID 44931783. ...
They both inexplicably die at age three because of brain edema. Victor later finds out they had been given the antibiotic ... This causes their brains to grow too large for their skulls, killing them. Their parents, however, were told their children had ...
Edema is the build-up of fluid within the brain tissue. Usually, the ring enhancement is directed toward the cortical surface. ... This cognitive impairment is associated with the loss of brain tissue, known as brain atrophy which is a result of the ... doi:10.1093/brain/awn098. PMC 2442427. PMID 18535080. Yiu EM, Laughlin S, Verhey LH, Banwell BL (2013). "Clinical and Magnetic ... A mass effect is the effect of a mass on its surroundings, for example, exerting pressure on the surrounding brain matter. ...
Headaches due to multiple factors including brain lesions, edema, and papilledema. Mental confusion, loss of cognitive function ... Patients with RVCL develop vision loss, brain lesions, strokes, brain atrophy, and dementia. Patients with RVCL also exhibit ... Although brain and eye disease are universally present in patients with RVCL, the disease is truly a multi-system disorder ... All patients develop brain and eye disease, leading to disability, vision loss, and premature death. All patients with RVCL ...
In the larger doses of donanemab, patients had cerebral edema (brain swelling). Cerebral edema is commonly known as ARIA-E, ... No patients had ARIA-E but there were cases of ARIA-H leaving small haemorrhages in the brain. The two cases with ARIA-H were ... A PET scan was also used to measure the amount of plaque in the brain. TRAILBLAZER-ALZ was the method used to improve the ... Aβ peptides are deposited in the brain and when in excess will bind together to create a protein plaque. Donanemab targets this ...
In 2018 she suffered a cerebral edema and underwent emergency brain surgery. She died of leukemia. Briceño was awarded the Emma ...
Harmful chemicals damage the blood-brain barrier. Cerebral edema (swelling of the brain) occurs due to leakage of large ... This "vasogenic edema" causes compression of and damage to brain tissue (Freye 2011; Acquired Mitochondropathy-A New Paradigm ... If and when the brain is reperfused, a number of factors lead to reperfusion injury. An inflammatory response is mounted, and ... The ischemic (ischaemic) cascade is a series of biochemical reactions that are initiated in the brain and other aerobic tissues ...
Possible problems that arise from the surgery include hemorrhage, brain edema, and hemiparesis. MRIs are typically done after 1 ... In CT scans, the presence of PNETs will be indicated by an elevated density and an increase in volume of the brain. The CT scan ... Another essential difference between them is the location of their respective blood vessels within the brain. It has also been ... It is a rare disease occurring mostly among children, accounting for 1.9 to 7% of childhood brain tumors. Symptoms involve ...
In 2007, Krista Mørkøre developed a cerebral edema, causing her brain to swell. This resulted in paralysis of the right side of ...
The cytokines trigger edema, endothelial thickening, and infiltration of neutrophils in brain tissue. Two cytokines, interferon ... In some cases, inflammation of the brain can be seen if the brain or the nervous system is attacked as a result of problems ... Some pathogens are also capable of passing over the blood-brain barrier and entering the brain through the bloodstream, despite ... If the swelling appears to have increased to a dangerous level, surgery may be needed to relieve pressure on the brain. The ...
AVPR1b has also shown involvement in regulation of brain water content and cerebral edema. This was revealed as increased ... Subsequent studies have shown that it is also present in the brain and some peripheral tissues. Inactivation of the Avpr1b gene ... The increase after a reduction of brain water content from salt water loading indicated AVPR1B's role in the neuroendocrine ... Brain and Behavior. 6 (7): 653-60. doi:10.1111/j.1601-183X.2006.00294.x. PMC 2486432. PMID 17284170. Wersinger SR, Kelliher KR ...
2007). "Minocycline-induced hypersensitivity syndrome presenting with meningitis and brain edema: a case report". Journal of ... Brain swelling and rheumatoid arthritis are rare side effects of minocycline in some people. Minocycline, like most ... Nonaka K, Nakazawa Y, Kotorii T (December 1983). "Effects of antibiotics, minocycline and ampicillin, on human sleep". Brain ... It crosses the blood-brain barrier better than doxycycline and other tetracyclines, reaching therapeutically relevant ...
"Progesterone administration modulates AQP4 expression and edema after traumatic brain injury in male rats". Experimental ... Allopregnanolone, a neurosteroid, aids the continued neurogenesis in the brain. Levels of allopregnanolone in the brain decline ... Studies Find Brains Grow New Cells Michael Specter: Rethinking the Brain - How the songs of canaries upset a fundamental ... Traumatic brain injuries vary in their mechanism of injury, producing a blunt or penetrating trauma resulting in a primary and ...
"Beneficial Effect of Agmatine on Brain Apoptosis, Astrogliosis, and Edema after Rat Transient Cerebral Ischemia." BMC ... Rapid elimination from non-brain organs of ingested (un-metabolized) agmatine by the kidneys has indicated a blood half life of ... Halaris A, Plietz J (2007). "Agmatine : metabolic pathway and spectrum of activity in brain". CNS Drugs. 21 (11): 885-900. doi: ... It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and ...
This can lead to cerebral edema, potentially resulting in seizures, permanent brain damage, or death. Therefore, significant ... Hypernatremia due to diabetes insipidus as a result of a brain disorder, may be treated with the medication desmopressin. If ... Rapidly lowering the sodium concentration with free water, once this adaptation has occurred, causes water to flow into brain ... Severe symptoms include confusion, muscle twitching, and bleeding in or around the brain. Normal serum sodium levels are 135- ...
"Neuroprotective and brain edema-reducing efficacy of the novel cannabinoid receptor agonist BAY 38-7271". Brain Research. 989 ( ... with proposed uses in the treatment of traumatic brain injury. It is a full agonist with around the same potency as CP 55,940 ... a novel highly selective and highly potent cannabinoid receptor agonist for the treatment of traumatic brain injury". CNS Drug ...
Damage to the brain caused swelling (cerebral edema), and Nixon slipped into a deep coma. He died at 9:08 p.m. on April 22, ... and traveled to his brain. He was taken to New York Hospital-Cornell Medical Center in Manhattan, initially alert but unable to ...
"Contribution of vasogenic and cellular edema to traumatic brain swelling measured by diffusion-weighted imaging". Journal of ... For example, anatomical MRI brain scans are often mapped to the MNI template as to represent all the brain scans in common ... For example, an anatomical MRI brain scan of a patient with severe brain abnormalities (i.e., a tumor or surgical procedure), ... "The MNI brain and the Talairach atlas". M. Sabuncu; S. K. Balci; M. E. Shenton; P. Golland (2009). "Image-driven Population ...
2015). "Toxic role of prostaglandin E2 receptor EP1 after intracerebral hemorrhage in mice". Brain Behav. Immun. 46: 293-310. ... correlations with angiogenesis and cerebral edema". Neurochem. Int. 58 (8): 872-9. doi:10.1016/j.neuint.2011.02.014. PMC ...
Marjorie Manning (Beverly Polcyn), a previous elderly multiple sclerosis patient suffering sepsis and pulmonary edema, comes in ... the girl finally awakens but just thrashes around and is sent for a new CT to diagnose possible brain damage. Dr. Julia Wise ( ...
CPP values above CPPopt are believed to cause hyperemia, i.e. to high cerebral blood flow that may cause cerebral edema and ... A high PRx indicating disturbed pressure autoregulation predicts poor outcome in traumatic brain injury. PRx varies with the ... in order to guide therapy to protect the brain from dangerously high or low cerebral blood flow. PRx uses mathematical ... Short pressure reactivity index versus long pressure reactivity index in the management of traumatic brain injury. J Neurosurg ...
Timmerman, Luke (2 June 2015). "ASCO Wrapup: Immunotherapy Shines, Hope For Brain Tumors, & The Great Cancer Drug Price Debate ... edema, fever, chills, myasthenia gravis, and flu-like symptoms. Pembrolizumab is a therapeutic antibody that binds to and ...
Problems with brain development can also be a factor. The brain undergoes a complicated process during development in which ... edema, or autoimmune processes. They are very medication and therapy-resistant, and the primary therapeutic goal is to stop ... Throughout the brain, the placement of these neurons is normally quite precise. If this system doesn't work exactly right, ... Brain abscesses or tumors can be-at least temporarily or partially, if not fully and permanently-surgically treated and ...
Blood-brain barrier - Semipermeable capillary border that allows selective passage of blood constituents into the brain Blood- ... This can be a result of several possible causes, including blast injury, swimming-induced pulmonary edema, and breathing gas ...
... appears to be particularly important to osmoregulation, and preventing edema-induced stroke, transient ischemic attack or ... and brain isoforms". Biochemistry. 30 (21): 5139-5145. doi:10.1021/bi00235a004. PMID 2036379. Froguel P, Zouali H, Sun F, Velho ... between the blood circulation and the interstitial spaces is critical in some cases of edema including cerebral edema. ... neural tube and cardiac defects in the early-developing brain, spine, and heart depend upon functional GLUT2 carriers, and ...
Simka M (May 2009). "Blood brain barrier compromise with endothelial inflammation may lead to autoimmune loss of myelin during ... Venous pathology is commonly associated with hypertension, infarcts, edema and transient ischemia, and occurs more often with ... Zamboni theorized that malformed blood vessels cause increased deposition of iron in the brain, which in turn triggers ... Lassmann H (July 2005). "Multiple sclerosis pathology: evolution of pathogenetic concepts". Brain Pathology. 15 (3): 217-22. ...
Ecuador told Cando's family that the cause was brain edema, but staff later stated the cause of death was cardiac arrest as the ...
Edema and fiber damage were not noted in another cohort of animals studied 9 days after landing. However, in additional studies ... Experimental Brain Research. Experimentelle Hirnforschung. Experimentation Cerebrale. 113 (1): 104-16. doi:10.1007/bf02454146. ... These included eccentric-like lesioned sarcomeres, myofibrillar disruptions, edema, and evidence of macrophage activation and ... edema occurs in the target anti-gravity muscles such as the soleus and the adductor longus (AL). This is thought to occur by ...
The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273-81. doi: ... 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction ... Glover M, Zuber AM, O'Shaughnessy KM (2009). "Renal and brain isoforms of WNK3 have opposite effects on NCCT expression". J. Am ...
... severe metabolic alterations and cerebral edema that can lead to brain death. In these cases the mortality without liver ... Bergeron, M; Swain, MS; Reader, TA; Grondin, L; Butterworth, RF (July 1990). "Effect of ammonia on brain serotonin metabolism ... Bergeron, M; Layrargues, GP; Butterworth, RF (September 1989). "Aromatic and branched-chain amino acids in autopsied brain ... Metabolic Brain Disease. 17 (4): 463-75. doi:10.1023/A:1021986624600. PMID 12602522. S2CID 19491464. Butterworth, RF (2003). " ...
... and in serious cases edema of the brain, apnea, coma, or respiratory failure. Treatment includes lowering leucine intake and a ... Zinnanti, William J.; Lazovic, Jelena (2012). "Interrupting the mechanisms of brain injury in a model of maple syrup urine ... "Classical maple syrup urine disease and brain development: Principles of management and formula design". Molecular Genetics and ...
... the brain does not receive optical information, through various causes (H54/B73) River blindness - blindness caused by long- ... Macular edema - distorted central vision, due to a swollen macula (H35.9) Retinal disorder, unspecified (H36.0) Diabetic ... poor or blurry vision due to either no transmission or poor transmission of the visual image to the brain (H53.0) Leber's ... a disconnection between the optic nerve and the brain and/or spinal cord (H57.9) Red eye - conjunctiva appears red typically ...
Joëlle Mogensen, 29, French singer (Il était une fois), pulmonary edema. Birch Monroe, 80, American country musician John ... Born: Martin Andersson, Swedish footballer Rachel Boston, American actress; in Signal Mountain, Tennessee Louis Brain, English- ...
Brain and development. 2002 Jul;34(4): 348-52 Lahat E, et al. Alice in Wonderland syndrome and infectious mononucleosis in ... Macular edema and surgical re-attachment for macula-off rhegmatogenous retinal detachment can also cause an increased ... may result from different areas of the brain being affected by migraine. Macropsia may present itself as a symptom of both ...
When taken with Parkinson's drugs other than L-DOPA, side effects include peripheral edema, fall, joint pain, cough, and ... "Making armor for the brain". The Jerusalem Post. Finberg JP, Lamensdorf I, Commissiong JW, Youdim MB (1996). "Pharmacology and ... somewhat compensating for the diminished quantities made in the brains of people with Parkinson's. Selegiline was the first ...
As a result, the muscle cells contract permanently, the communication between the brain and the muscles is disrupted and ... Vacuolar myelinopathy is characterized by widespread vacuolization of the myelinated axons (intramyelenic edema) in the white ... Brain Research. 497 (1): 64-71. doi:10.1016/0006-8993(89)90970-0. PMID 2551452. S2CID 140209787. Lobner, D; Piana, PM; Salous, ... "Dietary exposure to an environmental toxin triggers neurofibrillary tangles and amyloid deposits in the brain". Proceedings of ...
The brain swelling is likely a result of vasogenic edema, the penetration of the blood-brain barrier by fluids. This process ... One theory is that variations in brain size play a role, but the increase in brain volume from edema does not likely cause ... It appears to be a vasogenic edema (fluid penetration of the blood-brain barrier), although cytotoxic edema (cellular retention ... High-altitude cerebral edema (HACE) is a medical condition in which the brain swells with fluid because of the physiological ...
While the best brains of the country, whether in statesmanship or warcraft were in the frontline at Gauhati, the King had to ... Deaths from edema, Year of death uncertain). ...
Still other branches of the I-a axons synapse with interneurons leading to brain centers, e.g., the cerebellum, that coordinate ... There are also juxtacapillary (J) receptors, which respond to events such as pulmonary edema, pulmonary emboli, pneumonia, and ... Experimental Brain Research. 66 (1): 141-54. doi:10.1007/bf00236210. PMID 3582528. S2CID 22450227. Biswas A, Manivannan M, ... these receptors transduce sound for the brain. Cutaneous mechanoreceptors can also be separated into categories based on their ...
As the brain receives its plentiful supply of afferent information relating to ventilation, it is able to compare it to the ... A chest x-ray is useful to confirm or rule out a pneumothorax, pulmonary edema, or pneumonia. Spiral computed tomography with ... It is believed the central processing in the brain compares the afferent and efferent signals; and dyspnea results when a " ... A low level of brain natriuretic peptide is useful in ruling out congestive heart failure; however, a high level, while ...
The OECs were taken from the patient's olfactory bulbs in his brain and then grown in the lab, these cells were then injected ... Complications of spinal cord injuries include pulmonary edema, respiratory failure, neurogenic shock, and paralysis below the ... It results from lack of input from the brain that quells muscle responses to stretch reflexes. It can be treated with drugs and ... Its use in traumatic brain injury is also not recommended. Surgery may be necessary, e.g. to relieve excess pressure on the ...
Intracerebral hemorrhages and accompanying edema may disrupt or compress adjacent brain tissue, leading to neurological ... A CT scan is the best test to look for bleeding in or around your brain. In some hospitals, a perfusion CT scan may be done to ... In some hospitals, a perfusion MRI scan may be done to see where the blood is flowing and not flowing in your brain. Angiogram ... Substantial displacement of brain parenchyma may cause elevation of intracranial pressure (ICP) and potentially fatal ...
... with edema, lymphadenopathy, pruritus and common secondary bacterial infections Skin atrophy - loss of elasticity, the skin ... but are protected in vertebrates from the action of ivermectin by the blood-brain barrier. Ivermectin is thought to ...
... brain edema, intracranial hypertension, seizures, ataxia and coma). This could happen in two different ways: ammonia itself ... Bosoi, C. R.; Rose, C. F. (2009). "Identifying the direct effects of ammonia on the brain". Metab Brain Dis. 24 (1): 95-102. ... Hyperammonemia in the brain, typically occurring as a secondary complication of primary liver disease and known as hepatic ... encephalopathy, is a condition that affects glutamate/GABA-glutamine cycling in the brain. Current research into autism also ...
Atrophy of the brain begins to accelerate at around seventy years of age, which leads to a significant reduction in brain mass ... This can lead to congestive heart failure or pulmonary edema. Another example is the decline in muscle mass, which although ... The reduction of brain size can lead to issues with eyesight, cognition and hearing. Because falls are the most common ... Since the skull does not decrease in size with the brain, there is significant space between the two when this occurs which ...
Other brain regions regulated by retinoic acid and potentially disrupted by isotretinoin include the frontal cortex and the ... Scheinfeld N, Bangalore S (May 2006). "Facial edema induced by isotretinoin use: a case and a review of the side effects of ... A further effect of isotretinoin on the brain involves retinoic acid function in the hypothalamus, the hormone regulatory ... and abnormalities in brain function. Isotretinoin is classified as FDA Pregnancy Category X and ADEC Category X, and use is ...
Role of nitric oxide in blood-brain barrier permeability, brain edema and cell damage following hyperthermic brain injury. An ... in several brain regions exhibiting leakage of the blood-brain barrier (BBB), brain edema formation and cell injury. ... brain edema and cell injury. These neuroprotective effects were most marked in the EGB-761 pretreated rats. Our observations ... Ginkgolide B significantly attenuated upregulation of cNOS and iNOS in the brain and also reduced the BBB permeability ...
brain edema and those with a hematoma in the brain. A classifier build from measurements in these two frequency ranges can ... Volumetric electromagnetic phase-shift spectroscopy of brain edema and hematoma. Volumetric electromagnetic phase-shift ... from a limited pilot study with 46 healthy volunteers and eight patients with CT radiology confirmed brain edema and brain ... Edema/diagnóstico por imagem; Edema/patologia; Condutividade Elétrica; Feminino; Hematoma/diagnóstico por imagem; Hematoma/ ...
Brain Edema XV. Katayama, Yoichi. 236,75€. Retinal Degenerative Diseases. Anderson, Robert E. ...
Angiopoietin-like protein 1 decreases blood brain barrier damage and edema following focal cerebral ischemia in mice. ...
Congestion and edema of the brain, widespread perivenous demyelination mainly in the cerebral and cerebellar white matter, ... A computed tomographic scan on day 15 showed brain edema and multiple inflammatory/demyelination lesions in the subcortical ... brain edema; and disseminated intravascular coagulation.. Neurologic disease is a well-known extrapulmonary complication of M. ... M. pneumoniae RNA can be detected in brain tissue by nucleic acid hybridization (8), and the presence of the organism was ...
Computed tomography scan of the brain showed diffuse cerebral edema. A wet mount of cerebrospinal fluid obtained by lumbar ... The ameba migrates from the nose to the brain along the olfactory nerve through the cribriform plate, destroys brain tissue, ... and causes cerebral edema. The case fatality rate for PAM exceeds 97% (3), and the median time from symptom onset to death is 5 ...
... noncongenital insult to the brain from an external mechanical force, possibly leading to permanent or temporary impairment of ... Definition Traumatic brain injury (TBI) is a nondegenerative, ... Cerebral edema. Edema may be caused by the effects of the above ... Brain Trauma Foundation. Updated Brain Trauma Foundation guidelines for treating severe traumatic brain injury (TBI) in infants ... Mild traumatic brain injury in the United States, 1998--2000. Brain Inj. 2005 Feb. 19(2):85-91. [QxMD MEDLINE Link]. ...
Fatal brain edema after ingestion of ecstasy and benzylpiperazine Dtsch Med Wochenschr. 2001. ... A mass fragmentographic assay of 3-methoxytyramine in rat brain J Neurochem. 1976. ...
Brain swelling (cerebral edema). *Increased blood acid level (lactic acidosis). When to Contact a Medical Professional. ... This draws the water out of the bodys other organs, including the brain. ...
These patients show signs of acute encephalitis and diffuse brain edema. Signs of increased intracranial pressure are seen in ... Degeneration of cysts may be associated with a strong host inflammatory response in the brain tissue, which can produce signs ...
Meningoencephalitis, focal necrosis of neurons in cortex, basal ganglia, brain stem, extensive edema. Slight cuffing with ...
Money for Traumatic Brain Injury Victims. Lawyer to help you sue for medical expenses, pain and suffering, disability, ... suffered a head injury and died from brain edema.. "Brain edema leading to an expansion of brain volume has a crucial impact on ... Classically, two major types of traumatic brain edema exist: vasogenic due to blood-brain barrier (BBB) disruption resulting ... Cerebral contusion - Signs of cerebral contusion (bruising of the brain) include brain swelling (cerebral edema) and ...
Categories: Brain Edema Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 3 ...
... and diagnosis requires exclusion of other causes of pulmonary edema (eg, high-altitude pulmonary edema). ... Neurogenic pulmonary edema develops within a few hours after a neurologic insult, ... is a relatively rare form of pulmonary edema caused by an increase in pulmonary interstitial and alveolar fluid. ... 5] traumatic brain injury (TBI), [6] and seizures. [7] Neurogenic pulmonary edema most commonly develops within a few hours ...
Purinergic-Receptor-Stimulation-Reduces-Cytotoxic-Edema-and-Brain-Infarcts-in-Mouse-Induced-by-pone.0014401.s009.ogv 6.6 s, 320 ... Purinergic-Receptor-Stimulation-Reduces-Cytotoxic-Edema-and-Brain-Infarcts-in-Mouse-Induced-by-pone.0014401.s010.ogv 6.4 s, 320 ... Local-ATP-Generation-by-Brain-Type-Creatine-Kinase-(CK-B)-Facilitates-Cell-Motility-pone.0005030.s005.ogv 26 s, 441 × 336; 1.67 ... Local-ATP-Generation-by-Brain-Type-Creatine-Kinase-(CK-B)-Facilitates-Cell-Motility-pone.0005030.s006.ogv 14 s, 441 × 336; 1.82 ...
Hypoxic Ischemic Brain Injury and Cerebral Edema. This image shows a noncontrast CT in a patient with hypoxic brain injury and ... Brain assessment Neuroimaging with CT or MRI is done first to exclude intracerebral hemorrhage, subdural or epidural hematoma, ... If it is mild, damage proceeds slowly; thus, even if perfusion is 40% of normal, 3 to 6 hours may elapse before brain tissue is ... Hemorrhagic stroke Intracerebral Hemorrhage Intracerebral hemorrhage is focal bleeding from a blood vessel in the brain ...
Acute exacerbations of multiple sclerosis, cerebral edema associated with primary or metastatic brain tumor, craniotomy, or ... edema, pulmonary edema, syncope, tachycardia, thromboembolism, thrombophlebitis, vasculitis. ... In cerebral edema, dexamethasone sodium phosphate injection is generally administered initially in a dosage of 10 mg ... As sodium retention with resultant edema and potassium loss may occur in patients receiving corticosteroids, these agents ...
Computerized tomography scan of the brain showed no cerebral edema or evidence of bleeding. On August 18, he developed ... After excluding carbon monoxide and heavy metal poisoning, anoxic brain injury, and metabolic disorders, the treating ... choreoathetosis that progressed to involve both arms, legs, and both sides of his face; a brain magnetic resonance imaging ...
Diffuse scalp edema was noted, but the brain parenchyma, cerebrospinal fluid spaces, and bony structures appeared normal. A CT ... Brain infarction, or stroke, is uncommon in infants, with an incidence of 0.6 per 100,000 each year. Only 0.5-1% of these cases ... Magnetic resonance imaging (MRI) of the brain (Figure 2) 3 days later showed an area of infarction in the left posterior ... Sebire G. Cerebral venous sinus thrombosis in children: risk factors, presentation, diagnosis and outcome. Brain. 2005;128(3): ...
... develop cerebral edema severe enough to cause brain herniation. In these instances, decompressive craniectomy, hematoma ... Contrast-enhanced brain MRI provides detailed information about the brain parenchyma and is probably more accurate for ... Contrast-enhanced brain MRI provides detailed information about the brain parenchyma and is probably more accurate for ... Contrast-enhanced brain MRI provides detailed information about the brain parenchyma and is probably more accurate for ...
Olive leaf extracts may also prove helpful in stroke, brain edema, infarct volume and other neurological disorders. Olive leaf ... Subject: What does GABA Do in the Brain? GABA. GABA or Gamma Amino Butyric Acid is a neurotransmitter of the brain. It is ... The Brain. As mentioned above, GABA is an inhibitory neurochemical. It functions at the inhibitory synapses of the brain by ... During brain development, GABA also plays a significant role. It significantly controls the proliferation of brain progenitor ...
He was taken to surgery to drain the hematoma but suffered rapid brain edema and expired. ... The tear was healing well with minimal edema.. An intensivist provided care to the heavily sedated patient, who developed ... They were unable to palpate sutures due to edema. Blood pressure was normal. That night, nurses noted abnormal movements along ... Allegations of improper performance of vaginal delivery (including brachial plexus injuries from shoulder dystocia, brain ...
3D multimodal MRI brain glioma tumor and edema segmentation: a graph cut distribution matching approach ». Computerized Medical ... Isointense infant brain segmentation with a hyper-dense connected convolutional neural network ». IEEE 15th International ... Benchmark on automatic six-month-old infant brain segmentation algorithms: the iSeg-2017 challenge ». IEEE Transactions on ... Deep CNN ensembles and suggestive annotations for infant brain MRI segmentation ». Computerized Medical Imaging and Graphics. ...
A 3T MRI study on biphasic blood-brain barrier opening and the dynamics of edema formation. Journal of Cerebral Blood Flow and ... Trampel, R.; Reimer, E.; Huber, L.; Ivanov, D.; Heidemann, R. M.; Schäfer, A.; Turner, R.: Anatomical brain imaging at 7T using ... Opitz, A.; Windhoff, M.; Heidemann, R. M.; Turner, R.; Thielscher, A.: How the brain tissue shapes the electric field induced ... Isotropic submillimeter fMRI in the human brain at 7 T: Combining reduced field-of-view imaging and partially parallel ...
... gross examination revealed massive cerebral edema with uncal herniation and intracytoplasmic inclusions in the brain and spinal ... Screening of urine for drugs was negative, and computerized axial tomography of the brain was within normal limits. Later on ... At the Washington State Department of Health Public Health Laboratories a specimen of brain tissue obtained at autopsy also was ... Despite trauma, decomposition, and partial consumption of the specimen by maggots, the bat brain was positive for rabies by DFA ...
Small interfering RNA-mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema ... Induktion of Brain-Derived Neurotrophic Factor in Plaque-Associated Glial Cells of Aged APP23 Transgenic Mice ...
  • He died of intractable cerebral edema on day 17 of illness, 10 days after the onset of neurologic symptoms. (cdc.gov)
  • Computed tomography scan of the brain showed diffuse cerebral edema. (cdc.gov)
  • The ameba migrates from the nose to the brain along the olfactory nerve through the cribriform plate, destroys brain tissue, and causes cerebral edema. (cdc.gov)
  • Ischemic stroke is sudden neurologic deficits that result from focal cerebral ischemia associated with permanent brain infarction (eg, positive results on diffusion-weighted MRI). (msdmanuals.com)
  • Partial or complete thrombotic occlusion occurs most often at the main trunk of the middle cerebral artery and its branches but is also common in the large arteries at the base of the brain, in deep perforating arteries, and in small cortical branches. (msdmanuals.com)
  • Acute exacerbations of multiple sclerosis, cerebral edema associated with primary or metastatic brain tumor, craniotomy, or head injury. (nih.gov)
  • Computerized tomography scan of the brain showed no cerebral edema or evidence of bleeding. (cdc.gov)
  • On autopsy, gross examination revealed massive cerebral edema with uncal herniation and intracytoplasmic inclusions in the brain and spinal cord. (cdc.gov)
  • 1,2 When a cerebral vein is occluded, retrograde pressure prevents the drainage of local brain capillaries, inhibiting perfusion and causing infarction. (appliedradiology.com)
  • Cerebral ischemia-reperfusion injury in rats - A 3T MRI study on biphasic blood-brain barrier opening and the dynamics of edema formation. (mpg.de)
  • Occurrence of hepatic encephalopathy or coma in ALF is a poor prognostic sign and is associated with the development of cerebral edema, intracranial hypertension and subsequent mortality from brain herniation [ 7 ]. (intechopen.com)
  • Though advances in the care of the patient with ALF have led to both a decrease in the incidence and associated mortality of persons developing cerebral edema and intracranial hypertension [ 7 ], careful vigilance should be exercised because development and progression of encephalopathy can be rapid and fatal. (intechopen.com)
  • Aumento de los líquidos intra o extracelulares en el tejido cerebral. (bvsalud.org)
  • El edema cerebral citotóxico (hinchazón debida al aumento del líquido intracelular) indica un trastorno del metabolismo celular, y se asocia comúnmente con lesiones hipóxicas o isquémicas (ver HIPOXIA CEREBRAL). (bvsalud.org)
  • El aumento del líquido extracelular puede ser producido por un aumento de la permeabilidad capilar cerebral (edema vasogénico), gradiente osmótico, bloqueo local en las vías de los líquidos intersticiales, o por obstrucción del flujo del LCR (es decir, HIDROCEFALIA obstructiva). (bvsalud.org)
  • Computed tomography (CT) brain was suggestive of cerebral edema and the CT chest was suggestive of diffuse opacities in bilateral lung fields. (who.int)
  • An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (bvsalud.org)
  • Patients with primary brain tumours often develop vasogenic edema and increased intracranial pressure. (bvsalud.org)
  • hemorrhages or diffuse brain edema. (cdc.gov)
  • These patients show signs of acute encephalitis and diffuse brain edema. (medscape.com)
  • Diffuse scalp edema was noted, but the brain parenchyma, cerebrospinal fluid spaces, and bony structures appeared normal. (appliedradiology.com)
  • M. pneumoniae antigens were demonstrated by immunohistochemical analysis of brain tissue, indicating neuroinvasion as an additional pathogenetic mechanism in central neurologic complications of M. pneumoniae infection. (cdc.gov)
  • Degeneration of cysts may be associated with a strong host inflammatory response in the brain tissue, which can produce signs and symptoms of encephalitis. (medscape.com)
  • At the Washington State Department of Health Public Health Laboratories a specimen of brain tissue obtained at autopsy also was positive by DFA, and rabies virus was isolated by mouse inoculation. (cdc.gov)
  • Analysis at CDC also included viral isolation from sputum obtained on March 14 and a positive DFA and nucleotide sequence analysis result from brain tissue obtained at autopsy. (cdc.gov)
  • How the brain tissue shapes the electric field induced by transcranial magnetic stimulation. (mpg.de)
  • and iv) additional swelling of the brain tissue, leading to IHT, which adds even more damage to the brain tissue ( 11 , 12 ). (spandidos-publications.com)
  • Increased intracellular or extracellular fluid in brain tissue. (bvsalud.org)
  • Infection in the brain or the tissue that surrounds the brain , as well as a brain abscess . (medlineplus.gov)
  • Any acute central nervous system (CNS) insult can result in pulmonary edema. (medscape.com)
  • Acute severe hyponatremia may lead to brain edema with neurologic consequences and be lethal if not promptly diagnosed and treated. (oregonstate.edu)
  • Brain swelling (brain edema) from altitude sickness, carbon monoxide poisoning, or acute brain injury. (medlineplus.gov)
  • Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). (bvsalud.org)
  • a brain magnetic resonance imaging study was consistent with basal ganglia injury. (cdc.gov)
  • After excluding carbon monoxide and heavy metal poisoning, anoxic brain injury, and metabolic disorders, the treating physicians attributed his neurologic findings to sulfuryl fluoride poisoning, manifested by basal ganglia necrosis. (cdc.gov)
  • however, in patients with ongoing brain injury and elevated intracranial pressure (ICP), the NPE often persists. (medscape.com)
  • Often, the term brain injury is used synonymously with head injury, which may not be associated with neurologic deficits. (medscape.com)
  • Neurogenic pulmonary edema most commonly develops within a few hours after a neurologic insult, and is characterized by dyspnea, bilateral basal pulmonary crackles, and the absence of cardiac failure. (medscape.com)
  • Neurogenic pulmonary edema trigger zones may exist in these structures, with specific neurologic foci or centers producing massive sympathetic discharges that lead to neurogenic pulmonary edema. (medscape.com)
  • For example, allergy medications may be taken to relieve the swelling from allergies, blood thinners may be prescribed to treat blood clot in the leg which led to edema, diuretics may treat leg edema due to liver disease or congestive heart failure, and limiting sodium intake may also help (Hoffman, 2020). (differencebetween.net)
  • 0 No symptoms at all avoiding more brain injury [29, 30]. (who.int)
  • The symptoms of edema depend on the affected area, the amount of swelling, and the cause. (differencebetween.net)
  • VALUE RFVF 10050 ='Chills' 10100 ='Fever' 10120 ='Other symptoms of body temperature' 10121 ='Feeling cold' 10122 ='Feeling hot' 10123 ='Feeling hot and cold' 10150 ='Tiredness, exhaustion' 10200 ='General weakness' 10250 ='General ill feeling' 10300 ='Fainting (syncope)' 10350 ='Symptoms of fluid abnormalities' 10351 ='Edema' 10352 ='Excessive sweating, perspiration' 10353 ='Excessive thirst' 10400 ='Weight gain' 10450 ='Weight loss' 10451 ='Recent weight loss' 10452 ='Underweight' 10460 ='Symptoms of face, not elsewhere class. (cdc.gov)
  • Volumetric electromagnetic phase-shift spectroscopy of brain edema and hematoma. (bvsalud.org)
  • We describe the technology and report results from a limited pilot study with 46 healthy volunteers and eight patients with CT radiology confirmed brain edema and brain hematoma . (bvsalud.org)
  • brain edema and those with a hematoma in the brain . (bvsalud.org)
  • scalp incision reaching or crossing the Brain manipulations during hematoma midline with the craniotomy flap diameter evacuation could be more hazardous for the about 15 cm centered on the hematoma core. (who.int)
  • Neurogenic pulmonary edema (NPE) is a relatively rare form of pulmonary edema caused by an increase in pulmonary interstitial and alveolar fluid. (medscape.com)
  • No specific laboratory study confirms the diagnosis of neurogenic pulmonary edema (NPE). (medscape.com)
  • The pathogenesis of neurogenic pulmonary edema (NPE) is not completely understood. (medscape.com)
  • Within the central nervous system, the sites responsible for the development of neurogenic pulmonary edema are not fully elucidated. (medscape.com)
  • Experimentally, bilateral lesions of the nuclei in the medulla produce profound pulmonary and systemic hypertension and pulmonary edema. (medscape.com)
  • Alpha-adrenergic blockade (with phentolamine) and spinal cord transection at the C7 level prevent the formation of neurogenic pulmonary edema, suggesting an important role for sympathetic activation. (medscape.com)
  • Alterations in pulmonary vascular pressures appear to be the most likely Starling force to influence the formation of neurogenic pulmonary edema. (medscape.com)
  • People with pulmonary edema experience shortness of breath and low oxygen levels. (differencebetween.net)
  • Traumatic brain injury (TBI) is a nondegenerative, noncongenital insult to the brain from an external mechanical force, possibly leading to permanent or temporary impairment of cognitive, physical, and psychosocial functions, with an associated diminished or altered state of consciousness. (medscape.com)
  • Inconsistency in the definition and classification of traumatic brain injury (TBI), along with discrepancies in data collection, has made the epidemiology of TBI difficult to describe accurately. (medscape.com)
  • When our law firm represents traumatic brain injury (TBI) victims, we immediately start working on a strategy for obtaining the best possible compensation package for our client. (pritzkerlaw.com)
  • How Much is My Traumatic Brain Injury Case Worth? (pritzkerlaw.com)
  • The husband suffered severe traumatic brain injury. (pritzkerlaw.com)
  • Reported prognostic factors for poor short-term outcome in CVST include anatomical characteristics of disease such as the presence of brain herniation and hemorrhage, or features of the clinical presentation such as seizures, depressed consciousness, and altered mental status. (cdc.gov)
  • Contrast-enhanced brain MRI provides detailed information about the brain parenchyma and is probably more accurate for diagnosing CVT than non-contrast-enhanced magnetic resonance venography sequences. (lww.com)
  • Specifically, ascites is fluid buildup in the abdomen while edema is simply the medical term for swelling Their distinctions are discussed below. (differencebetween.net)
  • A computed tomographic scan on day 15 showed brain edema and multiple inflammatory/demyelination lesions in the subcortical white matter of both hemispheres and within the brain thalami, capsulae internae, midbrain, and pons. (cdc.gov)
  • Abnormal connection between the arteries and veins in the brain that usually forms before birth. (medlineplus.gov)
  • Role of nitric oxide in blood-brain barrier permeability, brain edema and cell damage following hyperthermic brain injury. (nih.gov)
  • Exposure of rats to heat stress at 38 degrees C for 4 h resulted in marked upregulation of constitutive NOS (cNOS) and a mild but significant expression of inducible NOS (iNOS) in several brain regions exhibiting leakage of the blood-brain barrier (BBB), brain edema formation and cell injury. (nih.gov)
  • Pretreatment with the potent antioxidative compound EGB-761 or its constituent, Ginkgolide B significantly attenuated upregulation of cNOS and iNOS in the brain and also reduced the BBB permeability disturbances, brain edema and cell injury. (nih.gov)
  • Our observations strongly suggest that (i) EGB-761 and Ginkgolide B pretreatment offer significant neuroprotection in hyperthermic brain injury, (ii) upregulation of cNOS and iNOS are injurious to the cell and, (iii) oxidative stress plays an important role in NOS expression and cell injury. (nih.gov)
  • While this is a small-scale pilot study , it illustrates the potential of VEPS to change the paradigm of medical diagnostic of brain injury through a VEPS classifier-based technology . (bvsalud.org)
  • Magnetic resonance imaging (MRI) of the brain (Figure 2) 3 days later showed an area of infarction in the left posterior parietal lobe and extending inferiorly into the left periventricular white matter, with adjacent foci of susceptibility effect suspected to be thrombosed cortical veins. (appliedradiology.com)
  • Infants with congenital heart disease are also at increased risk for brain infarction caused by arterial emboli. (appliedradiology.com)
  • undertaken from July 15th, 2017 to March 15th, 2018.The multicentrique de cohorte prospective a inclus des Glasgow Coma Scale helped to determine the severety of the patients consécutifs admis en phase aiguë d AVC, disease at admission. (who.int)
  • More than half of critically des patients avec AVC en phase aiguë présentent ill patients exhibit admission hyperglycemia with age, severity of stroke and known diabetes as its main associated principaux facteurs de risque a risk factors. (who.int)
  • For patient education resources, see the Brain and Nervous System Center and Stroke . (medscape.com)
  • During stroke the blood-brain barrier (BBB) is damaged which can result in vasogenic brain edema and inflammation. (uni-wuerzburg.de)
  • L-Theanine works by crossing the blood brain barrier and increasing dopamine and GABA levels in the brain. (vitanetonline.com)
  • It receives blood from a vein in the nasal cavity, runs backwards, and gradually increases in size as blood drains from veins of the brain and the DURA MATER. (bvs.br)
  • The reduced blood supply leads to decreased delivery of oxygen and glucose to affected areas of the brain. (uni-wuerzburg.de)
  • Edema has many causes such as varicose veins, too much salt intake, prolonged sitting or standing, and side effects of medications (i.e., those prescribed for diabetes, high blood pressure, inflammation, and pain). (differencebetween.net)
  • As for the leg edema due to heart disease, the swelling may lead to an added 10 or 20 pounds which can disrupt blood flow and cause skin ulcers. (differencebetween.net)
  • Problems with blood vessels and bleeding in the brain can cause a headache. (medlineplus.gov)
  • Blood flow to part of the brain stops. (medlineplus.gov)
  • Weakening of the wall of a blood vessel that can break open and bleed into the brain. (medlineplus.gov)
  • Clots in the veins prevent blood flow from leaving the brain (sinus thrombosis). (medlineplus.gov)
  • Oxygen and glucose deprivation (OGD) can cause upregulation of glucose uptake of brain endothelial cells. (uni-wuerzburg.de)
  • Thus, applications of neural probes are not limited to extracellular recording, brain-machine interface, and deep brain stimulation, but also include a wide range of new applications such as brain mapping, restoration of neuronal functions, and investigation of brain disorders. (mdpi.com)
  • Anatomical brain imaging at 7T using two-dimensional GRASE. (mpg.de)
  • In conclusion, the addition of MK801 during the OGD phase reduced significantly the glucose uptake after the subsequent reoxygenation phase in brain endothelial cells. (uni-wuerzburg.de)
  • Both hemodynamic (cardiogenic) and nonhemodynamic (noncardiogenic) components contribute to edema formation. (medscape.com)
  • Talk to Eric or Fred about a lawsuit for permanent brain damage seeking compensation for medical expenses, cost of care, lost income, pain and suffering, disability and other damages. (pritzkerlaw.com)
  • healthy subjects and those with a medical conditions in the brain . (bvsalud.org)
  • These different models allowed improvements on the understanding of intracranial hypertension establishment, neuroinflammation, immunology, brain hemodynamics and served to the development of therapeutic strategies. (spandidos-publications.com)
  • A classifier build from measurements in these two frequency ranges can provide instantaneous diagnostic of the medical condition of the brain of a patient , from a single set of measurements. (bvsalud.org)
  • 75% within the first 24 hours after the ictus management does not show superiority of and the edema volume may exceed the early surgery over best medical treatment [3- volume of the ICH itself [14-16]. (who.int)