Borna disease virus
A species in the genus Bornavirus, family BORNAVIRIDAE, causing a rare and usually fatal encephalitic disease in horses and other domestic animals and possibly deer. Its name derives from the city in Saxony where the condition was first described in 1894, but the disease occurs in Europe, N. Africa, and the Near East.
Newcastle disease virus
Foot-and-Mouth Disease Virus
Mononegavirales
Infectious bursal disease virus
Bornaviridae
Virus Replication
Aphthovirus
Parapoxvirus
Vero Cells
Horses
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Cercopithecus aethiops
Brain
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Viral Structural Proteins
Viral proteins that are components of the mature assembled VIRUS PARTICLES. They may include nucleocapsid core proteins (gag proteins), enzymes packaged within the virus particle (pol proteins), and membrane components (env proteins). These do not include the proteins encoded in the VIRAL GENOME that are produced in infected cells but which are not packaged in the mature virus particle,i.e. the so called non-structural proteins (VIRAL NONSTRUCTURAL PROTEINS).
Newcastle Disease
Hemorrhagic Disease Virus, Rabbit
Gene Expression Regulation, Viral
Marek Disease
Reverse transcription-nested polymerase chain reaction for detecting p40 RNA of Borna disease virus, without risk of plasmid contamination. (1/250)
Several methods for the detection of Borna disease virus (BDV) RNA have been reported, one being the reverse transcription-nested polymerase chain reaction (RT-nested PCR) method. However, due to the possibility of contamination of the cloned DNA in a reaction tube, false-positive results might be obtained by RT-nested PCR. To detect only BDV RNA without anxiety of contamination, we developed an RT-nested PCR system using "mRNA selective PCR kit". Using this system, cDNA of BDV p40 in the plasmid (up to 5 x 10(7) molecules) was not amplified. BDV specific sequence was amplified from total RNA (more than 50 pg) of MDCK/BDV cells, which were persistently infected with BDV. These results indicate that this mRNA selective RT-nested PCR system can specifically amplify target RNA as distinguished from plasmid contaminated. (+info)A serosurvey of Borna disease virus infection in wild rats by a capture ELISA. (2/250)
For a serological diagnostic test for Borna disease (BD), we developed a capture ELISA with specificity and sensitivity based on detection of antibodies against BD virus (BDV) p40 protein. Using our capture ELISA system, the antibody response of rats inoculated intracerebrally with BDV at 4 weeks after birth showed a sharp increase from 1 to 4 weeks postinoculation (p.i.) and a steady level after 5 weeks p.i. To investigate prevalence of BDV infection among wild rats, we examined sera of Rattus norvegicus in Kami-iso town, Oshima district, Hokkaido, suggesting that rats in this area had not been infected by BDV. (+info)Immortalized cell lines derived from mice lacking both type I and type II IFN receptors unify some functions of immature and mature dendritic cells. (3/250)
Cells with dendritic morphology obtained from several organs of mice lacking both type I and II IFN receptors were immortalized by a retrovirus and analysed for their phenotype and for their function to induce cognate immune responses in vitro and in vivo. Two cell lines called AG101 (skin) and AG116 (brain) were cloned and analysed in more detail. They constitutively expressed the cell surface markers CD45, CD11b, MHC class II, F4/80, N418, B7-2 and ICAM1 but were CD8- and B220-negative. Cells from both lines were capable of taking up ovalbumin (OVA). The processed protein was presented to the OVA-specific T cell hybridoma BO97.105 which responded specifically with the production of IL-2. AG101 and AG116 cells were able to induce a mixed lymphocyte reaction as shown by a 50-fold increase of IL-2 production over background. Naive T cells were stimulated by antigen-primed AG101 and AG116, resulting in a T cell proliferation which was 20-30 times over background, and in IL-2 production it was 10 times the background. The capacity of AG101 or AG116 cells to prime naive T cells was directly compared with freshly isolated and cultured cutaneous dendritic cells (DC) from 129 Sv/Ev mice (wtDC). After cognate T cell interaction, IL-6 (20-100-fold) and IL-12 p40 (100-1000-fold) were similarly up-regulated in either AG101, AG116 or mature wtDC. To analyse the capacity of the immortalized DC to induce antibodies in vivo, cell line AG116 was permanently infected with Borna disease virus (BDV) which is unable to replicate in adult mice. One hundred and twenty-nine Sv/Ev mice injected with different cell numbers of AG116 carrying BDV (but not control cells) produced antibodies against the viral BDVp40 and BDVp24 protein. Therefore, the cell lines AG101 and AG116 appear to unify some functions of immature and mature DC. They are able to pick up antigen and process it. In the absence of externally added cytokines, the antigen presented on AG101 or AG116 cells drives T cells with an efficiency similar to mature DC. The cloned cell lines may prove to be useful to study both immune response and replication of infectious agents in the absence of functional interferon receptors. (+info)Nuclear localization of the protein from the open reading frame x1 of the Borna disease virus was through interactions with the viral nucleoprotein. (4/250)
Previous studies have predicted the presence of a small open reading frame (ORFx1) located between ORF-1 and ORF-2 of the Borna disease viral (BDV) genome. The ORFx1 is expressed as a p10 protein that is localized in the nucleus and cytoplasm of BDV-infected cells. In this study, we cloned the nucleotide sequence of ORFx1 into expression vectors and showed that it is expressed as p10. An anti-p10 serum gave nuclear and cytoplasmic staining of cells persistently infected with BDV. Immunoprecipitation of p10 from BDV-infected cells coprecipitated the p40 nucleoprotein N and the 24-kDa viral phosphoprotein P. Transient transfection of noninfected cells showed that p10 and p40 can be coprecipitated and revealed that p10 localized in the cytoplasm was imported into the nucleus in the presence of the BDV p40 N. In vitro protein-protein interaction studies on solid phase showed the direct interaction of the p10 with the BDV N protein. The subcellular distribution of p10 and its interaction with p40 suggest that this protein may play a role in the nuclear replication and/or transcription of BDV. (+info)Pathogenesis of borna disease virus: granulocyte fractions of psychiatric patients harbor infectious virus in the absence of antiviral antibodies. (5/250)
Borna disease virus (BDV) causes acute and persistent infections in various vertebrates. During recent years, BDV-specific serum antibodies, BDV antigen, and BDV-specific nucleic acid were found in humans suffering from psychiatric disorders. Furthermore, viral antigen was detected in human autopsy brain tissue by immunohistochemical staining. Whether BDV infection can be associated with psychiatric disorders is still a matter of debate; no direct evidence has ever been presented. In the present study we report on (i) the detection of BDV-specific nucleic acid in human granulocyte cell fraction from three different psychiatric patients and (ii) the isolation of infectious BDV from these cells obtained from a patient with multiple psychiatric disorders. In leukocyte preparations other than granulocytes, either no BDV RNA was detected or positive PCR results were obtained only if there was at least 20% contamination with granulocytes. Parts of the antigenome of the isolated virus were sequenced, demonstrating the close relationship to the prototype BDV strains (He/80 and strain V) as well as to other human virus sequences. Our data provide strong evidence that cells in the granulocyte fraction represent the major if not the sole cell type harboring BDV-specific nucleic acid in human blood and contain infectious virus. In contrast to most other reports of putative human isolates, where sequences are virtually identical to those of the established laboratory strains, this isolate shows divergence in the region previously defined as variable in BDV from naturally infected animals. (+info)Inhibition of Borna disease virus replication by ribavirin. (6/250)
The guanosine analogue ribavirin was tested for antiviral activity in two neural cell lines, human oligodendrocytes and rat glia, against Borna disease virus (BDV) strains V and He/80. Ribavirin treatment resulted in lower levels of virus and viral transcripts within 12 h. Addition of guanosine but not adenosine resulted in a profound reduction of the ribavirin effect. Ribavirin appears to be an effective antiviral agent for treatment of BDV infection in vitro. A likely mechanism for its activity is reduction of the intracellular GTP pool, resulting in inhibition of transcription and capping of BDV mRNAs. (+info)T cell ignorance in mice to Borna disease virus can be overcome by peripheral expression of the viral nucleoprotein. (7/250)
Infection of neonates with Borna disease virus (BDV) induces severe meningoencephalitis and neurological disorder in wild-type but not in beta(2)-microglobulin-deficient mice of strain MRL (H-2(k)). Temporary in vivo depletion of CD8(+) T cells delayed BDV-induced disease for several weeks. Depletion of CD4(+) T cells had a similar beneficial effect, indicating that the BDV-induced neurological disorder in mice is a CD4(+) T cell-dependent immunopathological process that is mediated by CD8(+) T cells. Lymphocytes prepared from brains of diseased mice were mainly from the CD8(+) T cell subset. They showed up-regulation of activation markers and exerted strong MHC I-restricted cytotoxic activity against target cells expressing the BDV nucleoprotein p40. Infection of B10.BR (H-2(k)) or congenic C57BL/10 (H-2(b)) mice resulted in symptomless, lifelong persistence of BDV in the brain. Superinfection with a recombinant vaccinia virus expressing BDV p40 but not with other vaccinia viruses induced severe neurological disease and encephalitis in persistently infected B10.BR mice but not in persistently infected C57BL/10 mice, indicating that the disease-inducing T cell response is restricted to the nucleoprotein of BDV in H-2(k) mice. Our results demonstrate that the cellular arm of the immune system may ignore the presence of a replicating virus in the central nervous system until proper antigenic stimulation at a peripheral site triggers the antiviral response. (+info)Enhancement of Borna disease virus transcription in persistently infected cells by serum starvation. (8/250)
Transcription of Borna disease virus (BDV) in persistently infected MDCK (MDCK/BDV) cells increased in the fetal bovine serum free media as detected by Northern blot analysis. Especially, the amount of 1.9-kb RNA without cap formation at the 5' end and polyadenylation at the 3' end, increased as compared to other mRNA molecules of BDV. Growth arrest of MDCK/BDV cells observed in the condition of serum starvation might be important for increasing viral transcription. Since N-cadherin is the responsible factor for cell-to-cell contact, MDCK/BDV cells were cultured in calcium free medium which inhibits the interaction of N-cadherin. However, inhibition of cell-to-cell contact by N-cadherin is not effective on up regulation of viral transcription. Our finding in this study indicates that enhancement of BDV transcription by serum starvation is a useful technique for further investigation in understanding of mechanisms of BDV transcription. (+info) Borna disease (BoD) is a viral disease that affects animals, including horses, sheep, and goats. It is caused by the Borna virus (BoV), which is a member of the Paramyxoviridae family. The disease was first identified in Germany in 1892 and has since been reported in many countries around the world.
The symptoms of BoD can vary depending on the species of animal infected, but they typically include fever, loss of appetite, lethargy, difficulty walking or standing, seizures, and paralysis. The disease can be fatal in up to 90% of cases, especially in young animals.
BoV is primarily transmitted through the respiratory route, but it can also be spread through contact with infected animals or their tissues. Infected animals can shed the virus for several weeks before showing any symptoms, making it difficult to track the spread of the disease.
There is no specific treatment for BoD, and prevention is largely dependent on controlling the spread of the virus. Vaccination is not always effective against BoV, and there is currently no licensed vaccine available for horses or other animals. However, researchers are working to develop a vaccine that could provide protection against BoV.
In summary, Borna disease is a highly contagious and potentially fatal viral disease that affects animals, particularly horses, sheep, and goats. It is caused by the Borna virus, which can be transmitted through respiratory or contact routes, and there is currently no specific treatment or licensed vaccine available. Prevention relies on controlling the spread of the virus, and researchers are working to develop a vaccine that could provide protection against BoV.
Horse Diseases: Horse diseases refer to any health issues that affect horses, including equine influenza, strangles, and west nile virus. These diseases can be caused by a variety of factors, such as bacteria, viruses, parasites, and genetic predisposition.
Some common horse diseases include:
1. Equine Influenza (EI): A highly contagious respiratory disease caused by the equine influenza virus. It can cause fever, coughing, and nasal discharge.
2. Strangles: A bacterial infection of the lymph nodes, which can cause swelling of the neck and difficulty breathing.
3. West Nile Virus (WNV): A viral infection that can cause fever, weakness, and loss of coordination. It is transmitted by mosquitoes and can be fatal in some cases.
4. Tetanus: A bacterial infection caused by Clostridium tetani, which can cause muscle stiffness, spasms, and rigidity.
5. Rabies: A viral infection that affects the central nervous system and can be fatal if left untreated. It is transmitted through the saliva of infected animals, usually through a bite.
6. Cushing's Disease: A hormonal disorder caused by an overproduction of cortisol, which can cause weight gain, muscle wasting, and other health issues.
7. Laminitis: An inflammation of the laminae, the tissues that connect the hoof to the bone. It can be caused by obesity, overeating, or excessive exercise.
8. Navicular Syndrome: A condition that affects the navicular bone and surrounding tissue, causing pain and lameness in the foot.
9. Pneumonia: An inflammation of the lungs, which can be caused by bacteria, viruses, or fungi.
10. Colic: A general term for abdominal pain, which can be caused by a variety of factors, including gas, impaction, or twisting of the intestines.
These are just a few examples of the many potential health issues that can affect horses. Regular veterinary care and proper management can help prevent many of these conditions, and early diagnosis and treatment can improve the chances of a successful outcome.
Foot-and-mouth disease (FMD) is a highly contagious viral disease that affects cloven-hoofed animals such as cattle, pigs, sheep, and goats. It is caused by one of seven serotypes of the foot-and-mouth disease virus (FMDV), which are classified into two main genera: A and O. The disease is characterized by fever, blisters on the feet and in the mouth, and difficulty swallowing or eating.
The symptoms of FMD can vary depending on the severity of the infection and the age of the animal. In mild cases, the only symptoms may be a slight fever and blisters on the feet, while in severe cases, the blisters may become ulcers, and the animal may develop difficulty swallowing or eating, leading to weight loss and dehydration.
The virus is transmitted through contact with infected animals or their secretions, such as saliva, mucus, and manure. It can also be spread by contaminated feed or equipment, and by insects such as flies and midges. The incubation period for FMD is typically 3-14 days, but it can range from 2 to 30 days.
FMD is a significant threat to animal health and welfare, and can have severe economic consequences for farmers and the livestock industry as a whole. In addition, the disease can be transmitted to humans through close contact with infected animals, although this is rare.
There are several tests available to diagnose FMD, including serological tests such as ELISAs and virus isolation techniques. The disease is typically controlled through a combination of stamping out (killing all animals in an affected herd) and vaccination. Vaccination can be used to protect animals that are not yet infected, or to reduce the severity of the disease in animals that are already infected.
In summary, foot-and-mouth disease is a highly contagious viral disease that affects cloven-hoofed animals and can have severe economic and animal health consequences. It is characterized by fever, blisters on the feet and in the mouth, and difficulty swallowing or eating. Diagnosis is based on clinical signs and laboratory tests, and control measures include stamping out and vaccination.
Newcastle disease (ND) is a highly contagious viral disease that affects birds, particularly chickens and turkeys. It is caused by a paramyxovirus and can lead to significant economic losses in the poultry industry. The disease is named after the city of Newcastle upon Tyne in England, where it was first identified in 1926.
Symptoms of ND include:
* Respiratory problems such as coughing, sneezing, and difficulty breathing
* Decreased egg production or weight loss in laying hens
* Weakness, lethargy, and difficulty standing or walking
* Diarrhea, vomiting, and dehydration
* Swollen eyes, sinuses, and neck
Newcastle disease is transmitted through the air via droplets from infected birds, as well as through contaminated fomites such as feed, bedding, and other objects. It can also be spread by wild birds that have become carriers of the virus.
There are several forms of ND, including:
* Classical ND: This is the most common form of the disease and is characterized by rapid onset and high mortality rates in infected flocks.
* LaSota strain: This is a less virulent form of ND that is often used as a vaccine to protect against classical ND.
* Mesogenic ND: This form of the disease is characterized by slower onset and lower mortality rates than classical ND.
Diagnosis of ND typically involves a combination of clinical signs, laboratory tests such as PCR or ELISA, and postmortem examination of infected birds.
Control and prevention of ND primarily involve vaccination, sanitation, and biosecurity measures to reduce the risk of virus introduction and spread. In areas where the disease is endemic, strict controls on the movement of poultry and poultry products can help to minimize the risk of transmission.
Marek disease is a highly contagious and often fatal viral disease that affects chickens and turkeys. It is caused by a herpesvirus and is characterized by paralysis, loss of coordination, and difficulty breathing. The disease gets its name from the Czech veterinarian, Dr. Josef Marek, who first described it in 1907.
The virus that causes Marek disease is highly contagious and can be spread through direct contact with infected birds, as well as through contact with contaminated feathers, bedding, or other objects. Infected birds may not show any symptoms until they are stressed, exposed to cold weather, or experience a weakened immune system.
The symptoms of Marek disease can vary depending on the strain of the virus and the age and health of the bird. Some common symptoms include:
* Paralysis of the legs, wings, or beak
* Loss of coordination and balance
* Difficulty breathing or rapid breathing
* Swelling of the eyes or neck
* Weight loss
* Decreased egg production in laying hens
There is no cure for Marek disease, and it is usually fatal. However, vaccines are available to help prevent the disease in healthy birds. If you suspect that your bird has Marek disease, it is important to isolate it immediately and seek veterinary care as soon as possible.
Borna disease virus
The ancestral virus seems likely to have been a high AT content virus. Borna disease was first described in 1885 as "heated ... The Borna disease viruses 1 and 2 (BoDV-1 and BoDV-2) are members of the species Mammalian 1 orthobornavirus and cause Borna ... "N-terminal domain of Borna disease virus G (p56) protein is sufficient for virus receptor recognition and cell entry". Journal ... Wolff T, Pfleger R, Wehner T, Reinhardt J, Richt JA (April 2000). "A short leucine-rich sequence in the Borna disease virus p10 ...
W. Ian Lipkin
Lipkin, W. I; Hornig, M; Briese, T (2001). "Borna disease virus and neuropsychiatric disease--a reappraisal". Trends in ... "Does Borna Disease Virus Cause Mental Illness? , Columbia Public Health". www.publichealth.columbia.edu. January 31, 2012. ... Bode, L; Ludwig, H (2003). "Borna Disease Virus Infection, a Human Mental-Health Risk". Clinical Microbiology Reviews. 16 (3): ... "Borna disease is a neurotropic negative-strand RNA virus that infects a wide range of vertebrate hosts," causing "an immune- ...
Borna disease
March 2022). "New World camelids are sentinels for the presence of Borna disease virus". Transboundary and Emerging Diseases. ... Borna disease, also known as sad horse disease, is an infectious neurological syndrome of warm-blooded animals, caused by Borna ... Borna virus dangerous to humans after all". FOCUS Online. 2018-03-27. Retrieved 2022-06-09. "Human Infection with Borna Disease ... Borna diseases viruses 1 and 2 appear to have wide host ranges, having been detected in horses, cattle, sheep, new world ...
Bicolored shrew
... white-toothed shrew is a natural reservoir species for the Borna disease virus which is the causative agent of Borna disease, a ... "Shrews as Reservoir Hosts of Borna Disease Virus". Emerging Infectious Diseases. 12 (4): 675-677. doi:10.3201/eid1204.051418. ... Kamhieh S, Flower RL (June 2006). "Borna disease virus (BDV) infection in cats. A concise review based on current knowledge". ... Rott, R.; Herzog, S.; Bechter, K.; Frese, K. (1991). "Borna disease, a possible hazard for man?". Archives of Virology. 118 (3- ...
Bornaviridae
"Borna Disease Virus Infection in Animals and Humans". Emerging Infectious Diseases. 3 (3): 343-352. doi:10.3201/eid0303.970311 ... Diseases associated with bornaviruses include Borna disease, a fatal neurologic disease of mammals restricted to central Europe ... Richt, JA; Rott, R (2001). "Borna disease virus: a mystery as an emerging zoonotic pathogen". Vet J. 161 (1): 24-40. doi: ... Milad Azami, Farid Azizi Jalilian, Ali Khorshidi, Younes Mohammadi, Zeinab Tardeh, The association between Borna Disease Virus ...
Ștefan S. Nicolau
Nicolau and Galloway were also the first to identify the sensitivity of the Borna disease virus to lipid solvents, an ... "Preliminary studies on the biology of Borna disease virus". Journal of General Virology. 70 (12): 3507-3511. doi:10.1099/0022- ... The two were the first researchers to conduct experimental studies of the Borna disease in sheep and cattle and to describe the ... Nicolau, S.; Galloway, I. A. (1928), "Borna disease and enzootic encephalo-myelitis of sheep and cattle", Medical Research ...
Infections associated with diseases
Bode, L; Ludwig, H (2003). "Borna disease virus infection, a human mental-health risk". Clinical Microbiology Reviews. 16 (3): ... JC Virus and Simian Virus 40 Infection in Humans, and Association with Human Tumors". Polyomaviruses and Human Diseases. ... Lists of diseases, Infectious diseases, Infectious causes of cancer, Diseases and disorders, Inflammations). ... June 2010). "Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine". Cell ...
Tupaia (mammal)
A study investigating the effects of the Borna disease virus on treeshrews has given new insight into neurological disease. ... Sprankel, H., Richarz, K., Ludwig, H. and Rott, R. (1978). Behavior Alterations in Tree Shrews Induced by Borna Disease Virus. ... Their susceptibility to viruses has also piqued interest in using them to study immune responses to infections such as ... Recent studies have used treeshrews to study infectious, metabolic, neurological, and psychiatric diseases, as well as cancers ...
Avian bornavirus
In general these viruses show only about 65% sequence identity with mammalian Borna disease virus 1 (BoDV-1). The overall ... "Novel Borna Virus in Psittacine Birds with Proventricular Dilatation Disease". Emerging Infectious Diseases. 14 (12): 1883-1886 ... Avian bornaviruses have been reported, yet not proven, as the cause of proventricular dilatation disease (PDD), a disease of ... "Use of Avian Bornavirus Isolates to Induce Proventricular Dilatation Disease in Conures". Emerging Infectious Diseases. 16 (3 ...
Animal model of autism
Pletnikov, M. V.; Moran, T. H.; Carbone, K. M. (2002). "Borna disease virus infection of the neonatal rat: Developmental brain ... Much research has been done into the use of a rat model to show how Borna virus infection, exposure to valproic acid in utero, ... Centers for Disease Control (2008-02-08). "Mercury and vaccines (thimerosal)". Retrieved 2011-08-01. Crawley, J. N. (2012). " ... Klauck, S. M.; Poustka, A. (2006). "Animal models of autism". Drug Discovery Today: Disease Models. 3 (4): 313-318. doi:10.1016 ...
Perforin-1
Nöske K, Bilzer T, Planz O, Stitz L (1998). "Virus-Specific CD4+ T Cells Eliminate Borna Disease Virus from the Brain via ...
MiR-122
August 2010). "Modulation of miR-122 on persistently Borna disease virus infected human oligodendroglial cells". Antiviral ... Jangra RK, Yi M, Lemon SM (July 2010). "Regulation of hepatitis C virus translation and infectious virus production by the ... other RNA viruses and viral mimetics (e.g. poly(I:C)). Recent studies have shown that replication of hepatitis C virus (HCV) is ... Biomarkers in Liver Disease. V. B. Patel and V. R. Preedy. Dordrecht, Springer Netherlands: ISBN 978-94-007-7675-3, page 193- ...
Sue VandeWoude
... where she studied the virus associated with Borna disease. She joined the faculty of Colorado State University in 1990 and ... VandeWoude studies viruses including Feline Immunodeficiency Virus, Feline Leukemia Virus, and Feline Foamy Virus that infect ... Susan VandeWoude is a veterinarian and researcher in the United States, specializing in viral diseases of cats. She is ...
Risk factors of schizophrenia
Polio, measles, varicella-zoster, rubella, herpes simplex, maternal genital infections, Borna disease virus, and Toxoplasma ... It is a pathogenic theory of disease in which it is thought that a proximal cause of certain cases of schizophrenia is the ... In 2013 this dataset was expanded to identify in total 13 candidate loci for the disease, and also implicated calcium signaling ... An updated meta-analysis on CNVs for schizophrenia published in 2015 expanded the number of CNVs indicated in the disease, ...
Mady Hornig
She directs the clinical core of an international investigation of the role of Borna disease virus in human mental illness and ... based on neonatal rat infection with Borna disease virus. In 2004, Hornig published a controversial paper concluding that, in a ... In the 1990s, Hornig investigated the potential link between the Borna virus and depression in humans. Hornig has been ... In 2008, she published a study concluding that there was no association between presence of measles vaccine virus in the gut of ...
Causes of autism
Laboratory rats infected with Borna disease virus show some symptoms similar to those of autism but blood studies of autistic ... Viruses have long been suspected as triggers for immune-mediated diseases such as multiple sclerosis but showing a direct role ... or whether they are secondary to the disease processes. As autoantibodies are found in diseases other than ASD, and are not ... Is gluten the great etiopathogenic agent of disease in the XXI century?]" [Is gluten the great etiopathogenic agent of disease ...
Borna
... a family of viruses associated with Borna disease Borna disease virus Borna language (Democratic Republic of the Congo), a ... Look up Borna in Wiktionary, the free dictionary. Borna may refer to: Borna, Leipzig, a town in Saxony, Germany Borna, a ... a Croatian masculine given name Bertin Borna (1930-2007), a Beninese politician Borna disease, an infectious neurological ... India Borna (duke), the Duke of Dalmatia c. 810-821, a vassal of the Frankish Empire Borna (given name), ...
Proventricular dilatation disease
Novel borna virus in psittacine birds with proventricular dilatation disease. Emerging infectious diseases 14(12), 1883-6.e ... Kristen Bole (2008-07-29). "UCSF researchers identify virus behind mysterious parrot disease". UCSF News Office. Archived from ... Proventricular dilatation disease (PDD) is an incurable probably viral disease of psittacine birds. It was first recognized and ... The virus can also affect the Purkinje cells of the heart, the adrenal medulla, the brain, and the spinal cord. On necropsy the ...
RNA virus
Borna disease virus Family Filoviridae - includes Ebola virus, Marburg virus Family Mymonaviridae Family Nyamiviridae Family ... virus Extra small virus Goji berry chlorosis virus Harmonia axyridis virus 1 Hepelivirus Jingmen tick virus Le Blanc virus ... includes Yellow fever virus, West Nile virus, Hepatitis C virus, Dengue fever virus, Zika virus Family Fusariviridae Family ... Viruses portal Virus classification List of viruses Viral replication Positive/negative-sense Animal viruses Double-stranded ...
List of MeSH codes (C02)
... kyasanur forest disease MeSH C02.782.417.505 - lassa fever MeSH C02.782.417.560 - marburg virus disease MeSH C02.782.417.762 - ... borna disease MeSH C02.782.580.250 - filoviridae infections MeSH C02.782.580.250.400 - hemorrhagic fever, ebola MeSH C02.782. ... border disease MeSH C02.782.350.675.106 - bovine virus diarrhea-mucosal disease MeSH C02.782.350.675.200 - classical swine ... marburg virus disease MeSH C02.782.580.600 - paramyxoviridae infections MeSH C02.782.580.600.080 - avulavirus infections MeSH ...
List of MeSH codes (B04)
... borna disease virus MeSH B04.820.455.300 - filoviridae MeSH B04.820.455.300.200 - ebola-like viruses MeSH B04.820.455.300.650 ... borna disease virus MeSH B04.909.777.455.300 - filoviridae MeSH B04.909.777.455.300.200 - ebola-like viruses MeSH B04.909. ... border disease virus MeSH B04.820.250.700.150 - diarrhea viruses, bovine viral MeSH B04.820.250.700.150.100 - diarrhea virus 1 ... african horse sickness virus MeSH B04.820.630.550.100 - bluetongue virus MeSH B04.820.630.550.400 - hemorrhagic disease virus, ...
Virus
Many serious diseases such as rabies, Ebola virus disease, AIDS (HIV), avian influenza, and SARS are caused by viruses. The ... January 1999). "High seroprevalence of Borna virus infection in schizophrenic patients, family members and mental health ... Viruses are important pathogens of livestock. Diseases such as foot-and-mouth disease and bluetongue are caused by viruses. ... A virus has either a DNA or an RNA genome and is called a DNA virus or an RNA virus, respectively. The vast majority of viruses ...
COVID-19 pandemic in Croatia
Concerns over the virus began as soon as it began its rapid rise in China and its effects on the international scale became ... A day after, Croatian player Borna Ćorić confirmed he was infected as well, with organizers urging fans and citizens who were ... They left self-isolation on 18 March after none of them showed symptoms of the disease. On 24 March, Croatia national football ... On 12 March, the first recovery was reported, and on 18 March, the first death from the virus was confirmed. The pandemic in ...
Deep learning
AtomNet was used to predict novel candidate biomolecules for disease targets such as the Ebola virus and multiple sclerosis. In ... At the same time, many image generator tools were born. AI-based image generators usually work under GPT-3 technology. It is ... Modern deep learning tools demonstrate the high accuracy of detecting various diseases and the helpfulness of their use by ...
COVID Moonshot
It was possible to sequence the virus and characterize key proteins extremely quickly because the new virus was somewhat ... "Structural Genomics Centers for Infectious Diseases". National Institute of Allergy and Infectious Diseases (NIAID). Retrieved ... von Delft, Annette; Mowbray, Charles; Nyaoke, Borna (24 December 2021). "The Moonshot: Crowdsourcing To Develop The First Open- ... Mpro does not mutate easily, so it is less likely that variants of the virus will adapt that can avoid the effects of such a ...
Aral Sea
In 1971, weaponized smallpox from the island reached a nearby ship, which then allowed the virus to spread to the city of Aral ... In June 2007, BBC World broadcast a documentary called Back From the Brink? made by Borna Alikhani and Guy Creasey, which ... and infectious diseases are common ailments. Liver, kidney, and eye problems can also be attributed to the toxic dust storms. ... Archives of Disease in Childhood. 88 (11): 966-968. doi:10.1136/adc.88.11.966. PMC 1719339. PMID 14612357. Small, Ian; van der ...
Wheat
There are many wheat diseases, mainly caused by fungi, bacteria, and viruses. Plant breeding to develop new disease-resistant ... Pronin, Darina; Borner, Andreas; Weber, Hans; Scherf, Ann (10 July 2020). "Wheat (Triticum aestivum L.) Breeding from 1891 to ... Both of these diseases are soil borne. Stem rust diseases: Caused by basidiomycete fungi e.g. Ug99 Viral diseases: Wheat ... A wide range of organisms infect wheat, of which the most important are viruses and fungi. The main wheat-disease categories ...
Gluten-related disorders
A four-of-five rule was proposed 2010 for confirming celiac disease, with the disease confirmed if at least four of the ... Despite its name, DH is neither related to nor caused by herpes virus: the name means that it is a skin inflammation having an ... Pronin, Darina; Borner, Andreas; Weber, Hans; Scherf, Ann (10 July 2020). "Wheat (Triticum aestivum L.) Breeding from 1891 to ... A survey of geriatrics with celiac disease in Finland revealed that the incidence of disease was much higher than the general ...
Execution of Imam Khomeini's Order
... virus yjc.ir The Iranian vaccine neutralizes the British virus mehrnews.com The Iranian vaccine neutralized the British virus ... "The country's first special pharmaceutical economic zone was registered in Alborz". Borna News. Retrieved 3 September 2018. " ... research on the medicine of the disease, launching the 4030 phone line with the help of 2,200 doctors and paramedics for ... the results show that this vaccine also neutralizes the British mutated COVID-19 virus. This vaccine has passed its phase 2 and ...
Roaring Twenties
A new woman was born-a "flapper" who danced, drank, smoked and voted. This new woman cut her hair, wore make-up, and partied. ... In 1928, Scottish biologist Alexander Fleming discovered a substance that killed a number of disease-causing bacteria. In 1929 ... "was carried about America by the rural-evangelical virus". However, as Arthur S. Link emphasized, the progressives did not ...
Rafael Nadal
"Inside the rare disease tennis champ Rafael Nadal battles to maintain solid footing". The Palm Beach Post. Retrieved 7 ... Later, he was upset by Borna Ćorić at the quarterfinals of the 2014 Swiss Indoors. After the loss, he announced that he would ... Two weeks prior to the Australian Open, Nadal officially withdrew from the tournament citing a stomach virus. Nadal's ... Nadal lost in the opening round at the Cincinnati Masters to eventual champion Borna Ćorić. Despite this setback, Nadal was the ...
Obstructive sleep apnea
The Epstein-Barr virus, for example, is known to be able to dramatically increase the size of lymphoid tissue during acute ... Stroke and other cardiovascular diseases are related to OSA, and those under the age of 70 have an increased risk of early ... Borner, Urs; Tschopp, Kurt (2021-03-30). "Night-to-night variability in obstructive sleep apnea using peripheral arterial ... This repeated brain hypoxia is also considered to be a cause of Alzheimer's disease. Diagnosis of obstructive sleep apnea is ...
Borna [bor′nә] disease virus - Volume 15, Number 9-September 2009 - Emerging Infectious Diseases journal - CDC
Emerging Infectious Diseases. 2009;15(9):1452. doi:10.3201/eid1509.e11509.. APA. (2009). Borna [bor′nә] disease virus. Emerging ... Borna disease virus was named after the town of Borna in Saxony, southeastern Germany, where in 1885 many horses in a German ... Borna disease virus and its role in neurobehavioral disease. Washington: ASM Press; 2002. ... Borna [bor′nә] disease virus. Volume 15, Number 9-September 2009 ...
Mechanism of the antiviral action of 1-beta-D-arabinofuranosylcytosine on Borna disease virus. - Institut Pasteur
... negative-stranded RNA virus that causes neurological diseases in a variety of warm-blooded animal species. Recently, we showed ... This finding was surprising for an RNA virus, since Ara-C is a DNA polymerase inhibitor. Thus, we sought to better define the ... Borna disease virus (BDV) is a nonsegmented, negative-stranded RNA virus that causes neurological diseases in a variety of warm ... Mechanism of the antiviral action of 1-beta-D-arabinofuranosylcytosine on Borna disease virus.. ...
Sindromul de oboseală cronică - Wikipedia
The Association Between Borna Disease Virus and Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis (PDF). ... Disease Ontology, accesat în 15 mai 2019. *^ a b c Monarch Disease Ontology release 2018-06-29sonu[*][[Monarch Disease Ontology ... release 2018-06-29sonu (Release of the Monarch Disease Ontology),​]]. Verificați valoarea ,titlelink=. (ajutor); ,access-date= ...
Indulging Idiots: Looking for XMRV in vaccines | ScienceBlogs
Over the past 30 years, numerous studies have linked Borna disease virus (BDV) with mental illnesses such as bipolar disorder, ... So you have had the underlying virus, and then amplified it with that vaccine, and then set off the disease, such that your ... No Evidence of Murine Leukemia Virus-Related Viruses in Live Attenuated Human Vaccines. Guess what. ... No Evidence of Murine Leukemia Virus-Related Viruses in Live Attenuated Human Vaccines. Switzer. Their conclusion: "We found no ...
endogenous viral DNA | Virology Blog
... and inhibition of Borna disease virus replication by viral DNA in the ground squirrel genome. You can find TWiV #303 at www. ... TWiV 303: Borna this way. This Week in Virology / By Vincent Racaniello ... On episode #303 of the science show This Week in Virology, the TWiV team discusses transmission of Ebola virus, ...
MH DELETED MN ADDED MN
Border disease virus B4.909.777.310.700.100 Borna disease virus B4.909.777.455.149.135 Bornaviridae B4.909.777.455.149 Boron ... Hemorrhagic Disease Virus, Epizootic B4.909.777.714.550.400 Hemorrhagic Disease Virus, Rabbit B4.909.777.162.500.380 ... Lujo virus B4.909.777.80.70.100.525 Lumpy skin disease virus B4.909.204.783.160.150.500 Lunch G7.203.300.590.560 G7.203.650.353 ... Newcastle disease virus B4.909.777.455.600.650.70.600 Nidovirales B4.909.777.500 Nigericin D3.830.620 Nipah Virus B4.909. ...
DeCS
Borna disease virus Entry term(s). Encephalomyelitis Virus, Enzootic Enzootic Encephalomyelitis Virus Near East Equine ... virus de la enfermedad de Borna. Entry term(s). virus de la encefalomielitis equina del Oriente Próximo virus de la ... Virus de la maladie de Borna Entry term(s):. Encephalomyelitis Virus, Enzootic. Enzootic Encephalomyelitis Virus. Near East ... Borna disease virus - Preferred Concept UI. M0002827. Scope note. A species in the genus Bornavirus, family BORNAVIRIDAE, ...
A narrative review on the similarities and dissimilarities between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)...
... as well as inflammatory or autoimmune diseases. It is concluded that sickness behavior and ME/CFS are two different conditions. ... ME/CFS is a chronic disease underpinned by a state of energy depletion. While sickness is an acute response to infection/injury ... Borna disease virus, Chlamydia pneumoniae and Borrelia burgdorferi [182].. In summary, sickness behavior and ME/CFS are related ... CA = breast carcinoma; CVD = cardiovascular disease; IBD = inflammatory bowel disease; MS = multiple sclerosis; PD = ...
Avian Borna Virus (PDD) - Animal Genetics
ABV is believed to be the primary agent for Proventricular Dilitation Disease (PDD). New Publication! Diagnosis of Avian Borna ... Animal Genetics offers rtPCR and ELISA testing for Avian Borna Virus (ABV). ... Virus infection in psittaciformes by serum antibody detection and reverse transcription polymerase chain reaction assay using ... Borna disease virus (BDV) is a negative-stranded neurotropic RNA virus. A neurotropic virus is a virus which can infect nerve ...
Different pH requirements are associated with divergent inhibitory effects of chloroquine on human and avian influenza A...
To explore whether the low pH-dependency of influenza A viruses might affect the antiviral effects of chloroquine at clinically ... This timing approximately corresponds to that of virus/cell fusion. Moreover, there was a clear correlation between the EC50 of ... chloroquine in vitro and the electrostatic potential of the HA subunit (HA2) mediating the virus/cell fusion process. Overall, ... achievable concentrations, we tested the antiviral effects of this drug on selected human and avian viruses belonging to ...
CIENCIASMEDICASNEWS: Occupation-Associated Fatal Limbic Encephalitis Caused by Variegated Squirrel Bornavirus 1, Germany, 2013 ...
Borna disease virus - fact and fantasy. Virus Res. 2011;162:162-72. DOIPubMed ... Inhibition of Borna disease virus replication by ribavirin. J Virol. 1999;73:7903-6.PubMed ... We obtained polyclonal antiserum against VSBV-1 and Borna disease virus (BoDV) N and P proteins from rabbits immunized with the ... Immune-mediated pathogenesis of Borna disease. Zentralbl Bakteriol Mikrobiol Hyg [A]. 1988;270:295-301. DOIPubMed ...
Pesquisa | Biblioteca Virtual em Saúde - BRASIL
Cerebrospinal fluid in Borna disease virus 1 (BoDV-1) encephalitis. Neumann, Bernhard; Hierl, Andreas; Wunderlich, Silke; Meier ... Borna disease virus 1 (BoDV-1) has been recognized as a rare cause of very severe encephalitis with rapid onset in central ... Borna disease virus 1 (BoDV-1) causes rare but often fatal encephalitis in humans. Late diagnosis prohibits an experimental ... Antibodies against viral nucleo-, phospho-, and X protein contribute to serological diagnosis of fatal Borna disease virus 1 ...
Professor Fiona Wood - Pobl - Prifysgol Caerdydd
Borna disease virus: The generation and review of a scientific study. Social Science & Medicine 63(4), pp. 1072-1083. (10.1016/ ... Borna disease virus: The generation and review of a scientific study. Social Science & Medicine 63(4), pp. 1072-1083. (10.1016/ ... Disease trajectories and ACT/RCPCH categories in paediatric palliative care. Palliative Medicine 24(8), pp. 796-806. (10.1177/ ... Disease trajectories and ACT/RCPCH categories in paediatric palliative care. Palliative Medicine 24(8), pp. 796-806. (10.1177/ ...
Value Set Concept Details
FIT -
Portfolio
MH DELETED MN ADDED MN
Border disease virus B4.909.777.310.700.100 Borna disease virus B4.909.777.455.149.135 Bornaviridae B4.909.777.455.149 Boron ... Hemorrhagic Disease Virus, Epizootic B4.909.777.714.550.400 Hemorrhagic Disease Virus, Rabbit B4.909.777.162.500.380 ... Lujo virus B4.909.777.80.70.100.525 Lumpy skin disease virus B4.909.204.783.160.150.500 Lunch G7.203.300.590.560 G7.203.650.353 ... Newcastle disease virus B4.909.777.455.600.650.70.600 Nidovirales B4.909.777.500 Nigericin D3.830.620 Nipah Virus B4.909. ...
MH DELETED MN ADDED MN
Border disease virus B4.909.777.310.700.100 Borna disease virus B4.909.777.455.149.135 Bornaviridae B4.909.777.455.149 Boron ... Hemorrhagic Disease Virus, Epizootic B4.909.777.714.550.400 Hemorrhagic Disease Virus, Rabbit B4.909.777.162.500.380 ... Lujo virus B4.909.777.80.70.100.525 Lumpy skin disease virus B4.909.204.783.160.150.500 Lunch G7.203.300.590.560 G7.203.650.353 ... Newcastle disease virus B4.909.777.455.600.650.70.600 Nidovirales B4.909.777.500 Nigericin D3.830.620 Nipah Virus B4.909. ...
MH DELETED MN ADDED MN
Border disease virus B4.909.777.310.700.100 Borna disease virus B4.909.777.455.149.135 Bornaviridae B4.909.777.455.149 Boron ... Hemorrhagic Disease Virus, Epizootic B4.909.777.714.550.400 Hemorrhagic Disease Virus, Rabbit B4.909.777.162.500.380 ... Lujo virus B4.909.777.80.70.100.525 Lumpy skin disease virus B4.909.204.783.160.150.500 Lunch G7.203.300.590.560 G7.203.650.353 ... Newcastle disease virus B4.909.777.455.600.650.70.600 Nidovirales B4.909.777.500 Nigericin D3.830.620 Nipah Virus B4.909. ...
Viruses - LABOKLIN Europe
Chronic wasting disease (CWD) information online: Friedrich-Loeffler-Institut
Laboratory for phylogenetic analyses with emphasis on influenza viruses and borna viruses ... Laboratory for phylogenetic analyses with emphasis on influenza viruses and borna viruses ... Laboratory for Molecular Virus Characterization. *Laboratory for NGS-based pathogen characterization and animal disease ... Laboratory for Molecular Virus Characterization. *Laboratory for NGS-based pathogen characterization and animal disease ...
Portal:Contents/Portals - MEpedia
Borna disease virus, Brucellosis, Chickenpox, Chronic Epstein-Barr virus, COVID-19, Ebola virus disease, Encephalitis ... Bacterial diseases, Category:Parasitic diseases, Category:Viral diseases ... Adrenal glands, Endocrine diseases and disorders, Endocrine signs and symptoms, Thyroid diseases ... Immune diseases and disorders, Immunomodulators, Immunostimulants, Infectious agents, Infectious diseases, Interferons, Toll- ...
Infectious diseases in shelter situations and their management
Aujeszkys Disease - Pseudorabies in cats. *Borna virus infection. *West Nile virus infection (WNV) ... Hartmann K (2006): Feline Leukemia Virus Infection. In: Greene CE (ed.): Infectious diseases of the dog and cat. 3rd ed., ... Sellon RK, Hartmann K (2006): Feline Immunodeficiency Virus Infection. In: Greene CE (ed.): Infectious diseases of the dog and ... Information about transmission and shedding of viruses is provided in Table 1, of other infectious diseases in Table 2. ...
Avian bornavirus (ABV) is the presumed causative agent of proventricular dilatation - bioerc-iend.org
Indirect Immunofluorescence Assay Antibodies against ABV had been detected by usage of an IIFA on persistently Borna disease ... In addition, infectious computer virus was isolated by using samples from brain and retina as described (25). To exclude the ... Avian bornavirus (ABV) is the presumed causative agent of proventricular dilatation disease (PDD), a significant fatal disease ... Experimental Disease of Cockatiels For inoculation reasons, we divided the cockatiels into 2 organizations (organizations ic ...
Djokovic donates 40,000 euros to Serbian town hit hard by virus
The town declared a state of emergency in late June due to the spread of the respiratory disease. ... Apart from Djokovic three other tennis players -- Grigor Dimitrov, Borna Coric and Viktor Troicki -- who participated in the ... Djokovic donates 40,000 euros to Serbian town hit hard by virus. July 02, 2020 , 09:54 ... Djokovic donates 40,000 euros to Serbian town hit hard by virus (Photo: Andrej ISAKOVIC / AFP). ...
Pathogen Advanced Molecular Detection Database|Archive|PHGKB
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases ... New bunya-like viruses: Highlighting their relations. Guterres Alexandro et al. Infection, genetics and evolution : journal of ... Borner Janus et al. BMC genomics 2017 Jan (1) 100 * Laboratory Testing of Donors and Stool for Fecal Microbiota Transplantation ... Genomic infectious disease epidemiology in partially sampled and ongoing outbreaks. Didelot Xavier et al. Molecular biology and ...
Skeletal Dysplasia 2
5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma | Nature Medicine
Fujita Institute for Virus Research, Kyoto University for providing Rig-I and the empty control vector and C. Borner (Institute ... de Fougerolles, A., Vornlocher, H.P., Maraganore, J. & Lieberman, J. Interfering with disease: a progress report on siRNA-based ... Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437, 1167-1172 (2005). ... Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441, 101-105 (2006). ...
Pritzker calls on retired health workers to join coronavirus fight - Chronicle Media
"This virus is here and it is in our communities.". The number of reported cases was 64 a week ago. Health officials expect ... J.B. Pritzker speaks to the media Saturday about the states efforts to stem the outbreak of the novel coronavirus disease, ... J.B. Pritzker grocery stores Illinois Illinois Department of Public Health c isolation pandemic Pritzker stay at home virus ... IDPH has reported just two people, a Chicago couple who contracted the virus in January, as having fully recovered, but Ezike ...
American Association of Zoo Veterinarians Conference 2012 - VINCausative agentInfectionEmerging InfectioViralProventricular DilatatCenters for DiseasPathogenNegative-strandedBornaviridaeReplication1885OutbreaksInfectionsAvianInfectious agentsAntiviralPathogensOutbreakSusceptibilityBacteriaChronicSerotypesReplicate2022ClinicalProteinHepatitisHorsesBirdsCommonlyRoleAnimalCasesTownCellGermanyGeneralEuropeControlCatsManagementRare
Causative agent4
- The causative agent was later found to be a negative-stranded RNA virus, which may also be a human pathogen. (cdc.gov)
- Bornavirus is the causative agent of Borna disease. (animalgenetics.com)
- Jan 29, 2015 · Search titles only By: Search Advanced search… Avian Borna Virus, the causative agent for Proventricular Dilatation Disease ("PDD") and several other neurological problems, has with good reason been an important issue in the avian community for some time. (bellatv.it)
- Avian bornavirus (ABV) is the presumed causative agent of proventricular dilatation disease (PDD), a significant fatal disease in psittacines. (bioerc-iend.org)
Infection4
- Diagnosis of Avian Borna Virus infection in psittaciformes by serum antibody detection and reverse transcription polymerase chain reaction assay using feather calami. (animalgenetics.com)
- This infection can be expressed in varying degrees from mild behavioral changes to severe neurological disease. (animalgenetics.com)
- While sickness is an acute response to infection/injury, the trigger factors in ME/CFS are less well defined and encompass acute and chronic infections, as well as inflammatory or autoimmune diseases. (biomedcentral.com)
- By testing human scra for their power to protect monkeys against yellow fever virus, Beeuwkes, Baucr, and Mahaffy (5) were able to determine the endemicity of yellow fever in parts of West Africa where cases were seldom recognized, and to show that certain other regions were free of the infection. (nih.gov)
Emerging Infectio2
- Emerging Infectious Diseases , 15 (9), 1452. (cdc.gov)
- In support of improving patient care, this activity has been planned and implemented by Medscape, LLC and Emerging Infectious Diseases. (blogspot.com)
Viral3
- On episode #303 of the science show This Week in Virology, the TWiV team discusses transmission of Ebola virus, and inhibition of Borna disease virus replication by viral DNA in the ground squirrel genome. (virology.ws)
- Some of us previously analysed the reported effects of chloroquine on replication of several viruses and concluded that the drug should be studied as a broad spectrum antiviral agent against emerging viral infections, being relatively well tolerated, cheap, and immediately available worldwide [ 9 ]. (biomedcentral.com)
- The past few years have seen a tremendous increase in the knowledge of the viral diseases of birds, thanks to new molecular-based and traditional diagnostic tools. (beautyofbirds.com)
Proventricular Dilatat1
- Bornavirus was first described in psittaciforms in 2008 by researchers at UCSF who were studying a group of five parrots suffering from Proventricular Dilatation Disease (PDD). (animalgenetics.com)
Centers for Diseas3
- Centers for Disease Control and Prevention. (cdc.gov)
- The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
Pathogen2
- In 1989, Lipkin identified the Borna virus using purely molecular tools, thus pioneering the practice of using molecular methods for pathogen discovery and surveillance. (nih.gov)
- Indirect Immunofluorescence Assay Antibodies against ABV had been detected by usage of an IIFA on persistently Borna disease pathogen (BDV)Cinfected Madin-Darby canine kidney cells. (bioerc-iend.org)
Negative-stranded3
- Borna disease virus (BDV) is a nonsegmented, negative-stranded RNA virus that causes neurological diseases in a variety of warm-blooded animal species. (archives-ouvertes.fr)
- Borna disease virus (BDV) is a negative-stranded neurotropic RNA virus. (animalgenetics.com)
- Using microarray technology, the group isolated a negative-stranded RNA virus from three of the five birds. (animalgenetics.com)
Bornaviridae3
- A species in the genus Bornavirus, family BORNAVIRIDAE , causing a rare and usually fatal encephalitic disease in horses and other domestic animals and possibly deer. (nih.gov)
- Especie del género Bornavirus, familia BORNAVIRIDAE, que causa una enfermedad encefalÃtica rara y por lo general mortal en caballos y otros animales domésticos y posiblemente ciervos. (bvsalud.org)
- This virus was determined to be a member of the Bornaviridae family. (animalgenetics.com)
Replication2
- As a weak base capable of accumulating within cellular organelles, chloroquine appears to be capable of interfering with pH-dependent steps in the replication of several viruses. (biomedcentral.com)
- Accordingly, the antiviral effects are exerted at an early step of virus replication. (biomedcentral.com)
18852
- Borna disease virus was named after the town of Borna in Saxony, southeastern Germany, where in 1885 many horses in a German cavalry regiment died of a fatal neurologic disease. (cdc.gov)
- Borna disease was first recognized in 1885 in cavalry horses in the town of Borna in Saxony, Germany. (animalgenetics.com)
Outbreaks3
- not only are disease outbreaks frequent, but new pathogens or virulent variants of endemic pathogens can emerge as a result of rapid transmission cycles and the consequent evolution and selection of infectious agents, such as viruses and bacteria. (abcdcatsvets.org)
- During "Microbe Hunting in the 21st Century," Lipkin will discuss state-of-the-art diagnostic and surveillance techniques that he and his colleagues use to rapidly assess and respond to new pathogenic microbes so that disease outbreaks may be mitigated and potentially averted. (nih.gov)
- Genomic infectious disease epidemiology in partially sampled and ongoing outbreaks. (cdc.gov)
Infections2
- So you have had the underlying virus, and then amplified it with that vaccine, and then set off the disease, such that your immune system could no longer control other infections, and created an immune deficiency. (scienceblogs.com)
- Under less-than-ideal conditions, incoming cats should be kept in quarantine for a minimum of 3 weeks (considering cats incubating feline parvo/panleukopenia virus (FPV) or FCV infections or reactivating latent feline herpesvirus (FHV) infections, and until their vaccination becomes effective). (abcdcatsvets.org)
Avian6
- Animal Genetics offers rtPCR and ELISA testing for Avian Borna Virus (ABV). (animalgenetics.com)
- To explore whether the low pH-dependency of influenza A viruses might affect the antiviral effects of chloroquine at clinically achievable concentrations, we tested the antiviral effects of this drug on selected human and avian viruses belonging to different subtypes and displaying different pH requirements. (biomedcentral.com)
- The broad-spectrum antiviral effects of chloroquine deserve particular attention in a time in which there are several cases of avian influenza A virus transmission to humans from poultry, and the availability of antiviral drugs is fundamental during preparation and evaluation of effective vaccines. (biomedcentral.com)
- We here report the results of an initial evaluation of susceptibility to chloroquine of human and avian influenza A viruses. (biomedcentral.com)
- It ran me about $250 to have a budgie tested for PBFD, Chlyamidia, and a few others.Furthermore, novel avian models of human diseases or embryonic development could also be established for research purposes. (bellatv.it)
- Diseases caused by previously unknown bacteria, fungi, parasites, and viruses had then to be dealt with by the avian veterinary community. (beautyofbirds.com)
Infectious agents2
- Viruses are infectious agents which cannot replicate outside a host cell. (beautyofbirds.com)
- Stress, poor nutrition etc. facilitate spread of infectious agents and development of disease. (abcdcatsvets.org)
Antiviral1
- Mechanism of the antiviral action of 1-beta-D-arabinofuranosylcytosine on Borna disease virus. (archives-ouvertes.fr)
Pathogens3
- While sickness behavior is a state of energy conservation, which plays a role in combating pathogens, ME/CFS is a chronic disease underpinned by a state of energy depletion. (biomedcentral.com)
- The constant movement of birds from differing geographic regions exposed them to diseases not found in their natural environments, making them vulnerable to a wide variety of pathogens. (beautyofbirds.com)
- As researchers identified the pathogens, they developed assays, tests and treatments, and the number and severity of the diseases caused by these pathogens began to lessen, so that now there are fewer cases of some diseases than were seen in the earlier years. (beautyofbirds.com)
Outbreak5
- Compartmentalisation of the shelter into individual sections can facilitate containment of a disease outbreak, should it occur. (abcdcatsvets.org)
- In 1999, he led the team that identified West Nile virus as the cause of an encephalitis outbreak in New York State. (nih.gov)
- The 33-year-old Djokovic donated the money to Novi Pazar, in Serbia's southwest, to help it fight a growing outbreak of the disease, the SportKlub TV sports channel reported. (com.vn)
- Gov. J.B. Pritzker speaks to the media Saturday about the state's efforts to stem the outbreak of the novel coronavirus disease, COVID-19, during a news conference Saturday, March 21 in Chicago. (chronicleillinois.com)
- SPRINGFIELD - Gov. J.B. Pritzker on Saturday, March 21 issued a "call to action" to retired health care workers to help fight Illinois' COVID-19 outbreak as the state enters its first day under a "stay-at-home" order aimed to stifle the spread of the disease. (chronicleillinois.com)
Susceptibility2
- Susceptibility to chloroquine appears to be dependent on the pH requirements of the viruses and the electrostatic potential of haemagglutinin subunit 2 (HA2), which is involved in virus/cell fusion. (biomedcentral.com)
- The Susceptibility of the Mouse to Yellow Fever When the susceptibility of the white mouse to the virus of yellow fever was announced in 1930 by Theiler (10, 11), it seemed that the "laboratory animal needed for replacing the monkey in the protection test had been found. (nih.gov)
Bacteria3
- New research confirms that cloacal swabs and fecal samples are not a reliable source of ABV RNA due to the inconsistent shedding of the virus and destructive forces like bacteria, enzymes, and other contaminants found in the feces. (animalgenetics.com)
- Obligate intracellular parasites include protozoa, bacteria and viruses. (beautyofbirds.com)
- A bacteriophage is a virus that infects bacteria and may integrate into the genetic material of its host cell. (beautyofbirds.com)
Chronic2
- Multiple sclerosis is a multifactorial chronic inflammatory disease of the central nervous system that leads to demyelination and neuronal cell death, resulting in functional disability. (bvsalud.org)
- Chronic wasting disease (CWD) of cervids (among others red deer, moose, reindeer) is a transmissible spongiform encephalopathy (TSE) similar to scrapie in small ruminants and BSE in cattle. (fli.de)
Serotypes1
- Genomic epidemiology of penicillin non-susceptible pneumococci with non-vaccine serotypes causing invasive disease in the USA. (cdc.gov)
Replicate2
- Well, if you are harboring one virus, and you replicate it a whole bunch, you've now broken the balance between the immune response and the virus. (scienceblogs.com)
- A virus must attach to and penetrate a cell membrane, release its genetic material and replicate within the co-opted cell. (beautyofbirds.com)
20221
- 2022. Monitoring and managing lifestyle behaviours using wearable activity trackers: a mixed methods study of views from the Huntington's disease community . (cardiff.ac.uk)
Clinical1
- For reptiles , we also offer growing viruses in cell culture for cases in which the above-mentioned diagnostic methods are not possible or have not yielded findings that match the clinical picture. (laboklin.com)
Protein2
- All viruses have a protective capsid, or coat, which is the virus' shell, composed of aggregated repeating protein subunits. (beautyofbirds.com)
- The nucleocapsid , or core, is the virus' genetic material, composed of nucleic acid (DNA or RNA) enclosed by the capsid protein coat. (beautyofbirds.com)
Hepatitis1
- Cholestatic hepatitis caused by glybenclamide in a patient with hepatitis C virus]. (nih.gov)
Horses1
- A similar disease had been observed in horses, sheep, and cattle for more than 100 years. (cdc.gov)
Birds4
- It is also important to note that in many cases birds infected with ABV may not develop any symptoms of Borna disease or PDD for years or even decades before the onset of disease. (animalgenetics.com)
- It is still unknown if a percentage of birds may never develop any symptoms of disease but may continue to function as a reservoir for ABV and allow the virus to infect other birds. (animalgenetics.com)
- When psittacines and other birds were brought to European and North American countries from Africa, Asia, South America and Australia during the bird craze of the 1970's and 1980's, few people considered the diseases these birds might bring with them. (beautyofbirds.com)
- To understand the effects of these viruses on the birds, it would be beneficial to start with some information about viruses in general. (beautyofbirds.com)
Commonly2
- A few commonly known neurotropic viruses are Rabies, Herpes virus, Poliovirus, and Japanese Encephalitis. (animalgenetics.com)
- Limbic encephalitis is commonly regarded as an autoimmune-mediated disease. (blogspot.com)
Role1
- Borna disease virus and its role in neurobehavioral disease. (cdc.gov)
Animal1
- Regenerative properties have been shown in various animal models of diseases of the central nervous system. (bvsalud.org)
Cases2
- It has long been believed that PDD is caused by an enveloped neurotropic virus that in some cases causes cytokine storm resulting from lymphocyte infiltration to the proventriculus (forestomach), ventriculus (gizzard), and areas of the small intestines. (animalgenetics.com)
- 3 cases of floxacillin-induced cholestatic liver disease]. (nih.gov)
Town1
- The town declared a state of emergency in late June due to the spread of the respiratory disease. (com.vn)
Cell6
- This timing approximately corresponds to that of virus/cell fusion. (biomedcentral.com)
- Moreover, there was a clear correlation between the EC 50 of chloroquine in vitro and the electrostatic potential of the HA subunit (HA2) mediating the virus/cell fusion process. (biomedcentral.com)
- Without a host cell, viruses cannot carry out their life-sustaining functions or reproduce. (beautyofbirds.com)
- Viruses are both acellular (a tissue or organism that lacks distinct cells) and intracellular (lives within a host cell) parasites. (beautyofbirds.com)
- A single, complete, fully developed virus particle independent of a host cell is called a virion. (beautyofbirds.com)
- The lipids in the envelope are derived from the cell that the virus took over. (beautyofbirds.com)
Germany2
- Utilizing the RNeasy Mini Package (QIAGEN, Hilden, Germany) based on the producers guidelines, we isolated total RNA for sequencing from 200 L of virus-containing supernatant. (bioerc-iend.org)
- Environmental and genetic factors seem to is the effect of mycotoxins from mold in the home and Lyme determine how a child adapts to the toxic insult and which disease, which is often passed on from the asymptomatic In Germany, only one in four children are still healthy, Autism Recovery: A Practical Resource-Oriented said Dr. Klinghardt. (dosingpdf.com)
General1
- Home 1 / Guidelines 2 / General 3 / GUIDELINE for Infectious diseases in shelter situations and their mana. (abcdcatsvets.org)
Europe1
- Its name derives from the city in Saxony where the condition was first described in 1894, but the disease occurs in Europe, N. Africa, and the Near East. (nih.gov)
Control2
- Furthermore, they focus on recommendations regarding prevention and control of infectious diseases. (abcdcatsvets.org)
- Good building design can aid infectious disease control. (abcdcatsvets.org)
Cats2
- In 1995, the virus was isolated from cats suffering from a "staggering disease. (animalgenetics.com)
- Cats showing any signs of infectious disease should be moved immediately to the isolation facilities. (abcdcatsvets.org)
Management1
- Persons who work in shelters are highly motivated but not always sufficiently trained in hygiene and disease management. (abcdcatsvets.org)
Rare1
- BACKGROUND AND OBJECTIVES: Motor Neuron Diseases (MND) are rare diseases but have a high impact on affected individuals and society. (bvsalud.org)
