A species of BORDETELLA with similar morphology to BORDETELLA PERTUSSIS, but growth is more rapid. It is found only in the RESPIRATORY TRACT of humans.
A genus of gram-negative, aerobic bacteria whose cells are minute coccobacilli. It consists of both parasitic and pathogenic species.
Infections with bacteria of the genus BORDETELLA.
A species of gram-negative, aerobic bacteria that is the causative agent of WHOOPING COUGH. Its cells are minute coccobacilli that are surrounded by a slime sheath.
A species of BORDETELLA that is parasitic and pathogenic. It is found in the respiratory tract of domestic and wild mammalian animals and can be transmitted from animals to man. It is a common cause of bronchopneumonia in lower animals.
A respiratory infection caused by BORDETELLA PERTUSSIS and characterized by paroxysmal coughing ending in a prolonged crowing intake of breath.
A suspension of killed Bordetella pertussis organisms, used for immunization against pertussis (WHOOPING COUGH). It is generally used in a mixture with diphtheria and tetanus toxoids (DTP). There is an acellular pertussis vaccine prepared from the purified antigenic components of Bordetella pertussis, which causes fewer adverse reactions than whole-cell vaccine and, like the whole-cell vaccine, is generally used in a mixture with diphtheria and tetanus toxoids. (From Dorland, 28th ed)
A set of BACTERIAL ADHESINS and TOXINS, BIOLOGICAL produced by BORDETELLA organisms that determine the pathogenesis of BORDETELLA INFECTIONS, such as WHOOPING COUGH. They include filamentous hemagglutinin; FIMBRIAE PROTEINS; pertactin; PERTUSSIS TOXIN; ADENYLATE CYCLASE TOXIN; dermonecrotic toxin; tracheal cytotoxin; Bordetella LIPOPOLYSACCHARIDES; and tracheal colonization factor.
One of the virulence factors produced by BORDETELLA PERTUSSIS. It is a multimeric protein composed of five subunits S1 - S5. S1 contains mono ADPribose transferase activity.
The lipopolysaccharide-protein somatic antigens, usually from gram-negative bacteria, important in the serological classification of enteric bacilli. The O-specific chains determine the specificity of the O antigens of a given serotype. O antigens are the immunodominant part of the lipopolysaccharide molecule in the intact bacterial cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
A species of BORDETELLA isolated from the respiratory tracts of TURKEYS and other BIRDS. It causes a highly contagious bordetellosis.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Agents that cause agglutination of red blood cells. They include antibodies, blood group antigens, lectins, autoimmune factors, bacterial, viral, or parasitic blood agglutinins, etc.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
The simplest saturated hydrocarbon. It is a colorless, flammable gas, slightly soluble in water. It is one of the chief constituents of natural gas and is formed in the decomposition of organic matter. (Grant & Hackh's Chemical Dictionary, 5th ed)
A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFAMIDE or CYCLOPHOSPHAMIDE.
A genus of anaerobic, irregular spheroid-shaped METHANOSARCINALES whose organisms are nonmotile. Endospores are not formed. These archaea derive energy via formation of methane from acetate, methanol, mono-, di-, and trimethylamine, and possibly, carbon monoxide. Organisms are isolated from freshwater and marine environments.
The systematic study of the complete DNA sequences (GENOME) of organisms.
A system of categories to which morbid entries are assigned according to established criteria. Included is the entire range of conditions in a manageable number of categories, grouped to facilitate mortality reporting. It is produced by the World Health Organization (From ICD-10, p1). The Clinical Modifications, produced by the UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES, are larger extensions used for morbidity and general epidemiological purposes, primarily in the U.S.
A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
Chemical reactions or functions, enzymatic activities, and metabolic pathways of living things.
Comprehensive, methodical analysis of complex biological systems by monitoring responses to perturbations of biological processes. Large scale, computerized collection and analysis of the data are used to develop and test models of biological systems.
Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
Sequential operating programs and data which instruct the functioning of a digital computer.
Databases devoted to knowledge about specific genes and gene products.
The portion of an interactive computer program that issues messages to and receives commands from a user.

PFGE and pertactin gene sequencing suggest limited genetic variability within the Finnish Bordetella parapertussis population. (1/39)

The outer-membrane protein pertactin (Prn) of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica is believed to function as an adhesin and is an important immunogen. The emergence of B. pertussis and B. bronchiseptica Prn variants has been reported. The aim of this study was to determine whether similar variation is found in B. parapertussis Prn and to characterize Finnish clinical B. parapertussis isolates that were collected in 1982-2000. Of 76 B. parapertussis isolates studied, seven (9 %) were found to have silent and non-silent nucleotide changes. In addition, one (1 %) had eight PQP repeats instead of nine. Three closely related B. parapertussis XbaI PFGE patterns were found. Genetic variation of B. parapertussis was found to be very limited, suggesting that B. parapertussis is a stable organism that is well-adapted to its own ecological niche.  (+info)

Comparison of culture and PCR for detection of Bordetella pertussis and Bordetella parapertussis under routine laboratory conditions. (2/39)

A PCR assay for the detection of Bordetella pertussis and Bordetella parapertussis was compared with the conventional culture method under routine laboratory conditions. Detection of B. pertussis was based on the amplification of a section of the IS481 insertion sequence and confirmation of positive results was based on a sequence of the pertussis toxin promoter region. Detection of B. parapertussis was based on the amplification of a section of the IS1001 insertion sequence. An internal control was included. Data were available for the period 28 November 2000 to 9 July 2003. In this period, 3096 patients were examined for infection with B. pertussis and B. parapertussis by culture and PCR on the same day. B. pertussis was found in 496 (16 %) patients; 208 (42 %) were diagnosed by PCR alone whereas 17 (3 %) were diagnosed by culture alone. B. parapertussis was found in 64 (2 %) patients. The sensitivity of the PCR was 97 % and of culture 58 %. The specificity of PCR was 93 % when regarding culture as 100 % sensitive. There was a significant relationship between laboratory method and age, as the superiority of PCR was most marked in the age group 0.5-3 years. The PCR assay proved highly sensitive for the diagnosis of pertussis. The specificity estimate of the PCR assay suffers from the influence of a gold-standard method with a low sensitivity. The PCR assay is considered highly specific due to the amplification of two different sequences in two separate assays.  (+info)

The BvgAS signal transduction system regulates biofilm development in Bordetella. (3/39)

The majority of Bordetella sp. virulence determinants are regulated by the BvgAS signal transduction system. BvgAS mediates the control of multiple phenotypic phases and a spectrum of gene expression profiles specific to each phase in response to incremental changes in the concentrations of environmental signals. Studies highlighting the critical role of this signaling circuitry in the Bordetella infectious cycle have focused on planktonically growing bacterial cells. It is becoming increasingly clear that the major mode of bacterial existence in the environment and within the body is a surface-attached state known as a biofilm. Biofilms are defined as consortia of sessile microorganisms that are embedded in a matrix. During routine growth of Bordetella under agitating conditions, we noticed the formation of a bacterial ring at the air-liquid interface of the culture tubes. We show here that this surface adherence property reflects the ability of these organisms to form biofilms. Our data demonstrate that the BvgAS locus regulates biofilm development in Bordetella. The results reported in this study suggest that the Bvg-mediated control in biofilm development is exerted at later time points after the initial attachment of bacteria to the different surfaces. Additionally, we show that these biofilms are highly tolerant of a number of antimicrobials, including the ones that are currently recommended for treatment of veterinary and human infections caused by Bordetella spp. Finally, we discuss the significance of the biofilm lifestyle mode as a potential contributor to persistent infections.  (+info)

Chromosome-borne class A BOR-1 beta-Lactamase of Bordetella bronchiseptica and Bordetella parapertussis. (4/39)

A narrow-spectrum clavulanic acid-inhibited class A beta-lactamase, BOR-1, was identified in a Bordetella bronchiseptica clinical isolate. It shared 45% amino acid identity with L-2 from Stenotrophomonas maltophilia. An identical beta-lactamase gene was found in B. bronchiseptica and Bordetella parapertussis reference strains that may contribute only in part to their resistance phenotype.  (+info)

Characterization of the filamentous hemagglutinin-like protein FhaS in Bordetella bronchiseptica. (5/39)

Filamentous hemagglutinin (FHA) is a large (>200 kDa), rod-shaped protein expressed by bordetellae that is both surface-associated and secreted. FHA mediates bacterial adherence to epithelial cells and macrophages in vitro and is absolutely required for tracheal colonization in vivo. The recently sequenced Bordetella bronchiseptica genome revealed the presence of a gene, fhaS, that is nearly identical to fhaB, the FHA structural gene. We show that although fhaS expression requires the BvgAS virulence control system, it is maximal only under a subset of conditions in which BvgAS is active, suggesting an additional level of regulation. We also show that, like FHA, FhaS undergoes a C-terminal proteolytic processing event and is both surface-associated and secreted and that export across the outer membrane requires the channel-forming protein FhaC. Unlike FHA, however, FhaS was unable to mediate adherence of B. bronchiseptica to epithelial cell lines in vitro and was not required for respiratory tract colonization in vivo. In a coinfection experiment, a DeltafhaS strain was out-competed by wild-type B. bronchiseptica, indicating that fhaS is expressed in vivo and that FhaS contributes to bacterial fitness in a manner revealed when the mutant must compete with wild-type bacteria. These data suggest that FHA and FhaS perform distinct functions during the Bordetella infectious cycle. A survey of various Bordetella strains revealed two distinct fhaS alleles that segregate according to pathogen host range and that B. parapertussis(hu) most likely acquired its fhaS allele from B. pertussis horizontally, suggesting fhaS may contribute to host-species specificity.  (+info)

Clearance of Bordetella parapertussis from the lower respiratory tract requires humoral and cellular immunity. (6/39)

Bordetella parapertussis and Bordetella pertussis are closely related species that cause whooping cough, an acute, immunizing disease. Their coexistence in the same host populations at the same time and vaccine studies showing that B. pertussis vaccines have little effect on B. parapertussis infection or disease suggest that the protective immunity induced by each does not efficiently cross protect against the other. Although the mechanisms of protective immunity to B. pertussis have been well studied, those of B. parapertussis have not. The present study explores the mechanism by which B. parapertussis is cleared from the lower respiratory tract by anamnestic immunity. Serum antibodies are necessary and sufficient for elimination of this bacterium, and CD4(+) T cells, complement, and neutrophils are required for serum antibody-mediated clearance. Mice lacking immunoglobulin A had no defect in their ability to control or clear infection. Interestingly, serum antibody-mediated clearance of B. parapertussis did not require Fc receptors that are required for antibody-mediated clearance of B. pertussis. Together these data support a model for the mechanism of protective immunity to B. parapertussis that is similar but distinct from that of B. pertussis.  (+info)

Comparative toll-like receptor 4-mediated innate host defense to Bordetella infection. (7/39)

Bordetella pertussis, B. parapertussis, and B. bronchiseptica are closely related species associated with respiratory disease in humans and other mammals. While B. bronchiseptica has a wide host range, B. pertussis and B. parapertussis evolved separately from a B. bronchiseptica-like progenitor to naturally infect only humans. Despite very different doubling times in vitro, all three establish similar levels of infection in the mouse lung within 72 h. Recent work has revealed separate roles for Toll-like receptor 4 (TLR4) in immunity to B. pertussis and B. bronchiseptica, while no role for TLR4 during B. parapertussis infection has been described. Here we compared the requirement for TLR4 in innate host defense to these organisms using the same mouse infection model. While B. bronchiseptica causes lethal disease in TLR4-deficient mice, B. pertussis and B. parapertussis do not. Correspondingly, TLR4 is critical in limiting B. bronchiseptica but not B. pertussis or B. parapertussis bacterial numbers during the first 72 h. Interestingly, B. bronchiseptica induces a TLR4-dependent cytokine response that is considerably larger than that induced by B. pertussis or B. parapertussis. Analysis of their endotoxins using RAW cells suggests that B. bronchiseptica lipopolysaccharide (LPS) is 10- and 100-fold more stimulatory than B. pertussis or B. parapertussis LPS, respectively. The difference in LPS stimulus is more pronounced when using HEK293 cells expressing human TLR4. Thus, it appears that in adapting to infect humans, B. pertussis and B. parapertussis independently modified their LPS to reduce TLR4-mediated responses, which may compensate for slower growth rates and facilitate host colonization.  (+info)

Characterization of serological responses to pertussis. (8/39)

We have compared the use of five nonvaccine antigens to the use of conventional vaccine antigens, pertussis toxin (PT), and filamentous hemagglutinin (FHA) for the serological diagnosis of pertussis by enzyme-linked immunosorbent assay (ELISA). The nonvaccine antigens included the catalytic region of adenylate cyclase toxin (CatACT), the C-terminal region of FHA (C-FHA), lipooligosaccharide (LOS), the peptidoglycan-associated lipoprotein (PAL), and the BrkA protein. The serological responses of individuals with culture-confirmed pertussis were compared to those of adults with no recent history of a coughing disease. An immunoglobulin G (IgG) ELISA for PT was the most sensitive (92.2%) test for the serodiagnosis of pertussis. Of the nonvaccine antigens, ELISA for IgG responses to CatACT (sensitivity, 62.8%), C-FHA (sensitivity, 39.2%), and LOS IgA (sensitivity, 29.4%) were less sensitive but could also distinguish culture-positive individuals from control individuals. The use of a combination of multiple ELISA targets improved the sensitivity of the assay for serological diagnosis. Elevated IgG and IgA antibody titers persisted for more than a year in the individuals with culture-confirmed pertussis.  (+info)

Bordetella parapertussis: | | | | |Bordetella parapertussis| | | ... World Heritage Encyclopedia, the aggregation of the largest online encyclopedias available, and the most definitive collection ever assembled.
Bordetella parapertussis ATCC ® 15311D-5™ Designation: Genomic DNA from Bordetella parapertussis Strain 522 TypeStrain=True Application:
Despite decades of worldwide pertussis vaccination, whooping cough is re-emerging in highly vaccinated countries (CDC 2002; Celentano et al. 2005). A rise in non-vaccine alleles coincident with widespread vaccination has been documented for Bordetella pertussis (Elomaa et al. 2005; Van Amersfoorth et al. 2005; Van Gent et al. 2009) leading some authors to propose that vaccine-driven epitope-evolution in B. pertussis is one factor-among several others (Berbers et al. 2009)-that may contribute to whooping cough re-emergence in humans (Mooi et al. 2001). However, it is not clear how Bordetella parapertussis-the other major aetiological agent of human whooping cough-might respond to the selective pressure exerted by large-scale pertussis vaccination. Here, we postulate that the widespread and long-term use of acellular subunit pertussis vaccines creates hosts that are more favourable for B. parapertussis.. All commercial whooping cough vaccines currently contain either killed whole cells or purified ...
ICD-10 A37.11 is whooping cough due to bordetella parapertussis with pneumonia (A3711). This code is grouped under diagnosis codes for certain infectious and parasitic diseases.
A37.11 ICD 10 CM Code for Whooping cough due to Bordetella parapertussis with pneumonia, Convert ICD 10 CM code A37.11 to ICD 9 CM code.
1ZBO: X-Ray Crystal Structure of Protein BPP1347 from Bordetella parapertussis. Northeast Structural Genomics Consortium Target BoR27.
|EM>Bordetella pertussis|/EM>, |EM>Bordetella parapertussis|/EM> and |EM>Bordetella bronchiseptica|/EM> are closely related Gram-negative Beta-proteobacteria that colonizes the respiratory tracts of mammals. |EM>B. parapertussis|/EM> causes whooping cough in a wide range of animals. D-Alanine is a necessary precursor in the biosynthesis of cell [...]
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Free, official coding info for 2018 ICD-10-CM A37.11 - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.
2KAT: Solution structure of protein BPP2914 from Bordetella parapertussis. Northeast Structural Genomics Consortium target BpR206
Bordetella pertussis and Bordetella parapertussis are the causal agents of whooping cough in humans. They produce diverse virulence factors, including adenylate cyclase-hemolysin (AC-Hly), a secreted toxin of the repeat in toxins (RTX) family with cyclase, pore-forming, and hemolytic activities. Post-translational modifications (PTMs) are essential for the biological activities of the toxin produced by B. pertussis. In this study, we compared AC-Hly toxins from various clinical isolates of B. pertussis and B. parapertussis, focusing on (i) the genomic sequences of cyaA genes, (ii) the PTMs of partially purified AC-Hly, and (iii) the cytotoxic activity of the various AC-Hly toxins. The genes encoding the AC-Hly toxins of B. pertussis and B. parapertussis displayed very limited polymorphism in each species. Most of the sequence differences between the two species were found in the C-terminal part of the protein. Both toxins harbored PTMs, mostly corresponding to palmitoylations of the lysine 860 residue
Directly proving aP vaccination puts treated people at risk of acquiring B. parapertussis is very difficult, but we hope our study highlights the need for more thorough B. parapertussis epidemiological data and encourages further work in this neglected area. If our experiments are capturing the phenomenology of what is happening under aP vaccination in humans, it may be important to consider the introduction of vaccines that better protect against both bordetellae; for example, live attenuated B. pertussis nasal vaccines (Mielcarek et al. 2006), wP vaccines containing both B. pertussis and B. parapertussis (Burianova-Vysoka et al. 1970), or supplementation of aP vaccines with B. parapertussis protective antigens (Zhang et al. 2009a). An enhanced understanding of the evolutionary consequences of widespread aP vaccination is needed in order to optimize the next generation of vaccination strategies and fully reap the benefits of this powerful medical intervention ...
Pertussis (whooping cough) is a respiratory tract infection characterized by a paroxysmal cough. The most common causative organism is Bordetella pertussis (see the image below), though Bordetella parapertussis has also been associated with this condition in humans.
Buy Azitrobac Online! Azitrobac is a macrolide antibiotic of azalides group. Azitrobac inhibits RNA-dependent protein synthesis of sensitive microorganisms. It active against gram-positive bacteria: Staphylococcus aureus, Streptococcus spp. (including Streptococcus pneumoniae, Streptococcus pyogenes group A); gram-negative bacteria: Haemophilus influenzae, Haemophilus parainfluenzae, Haemophilus ducreyi, Moraxella catarrhalis, Escherichia coli, Bordetella pertussis, Bordetella parapertussis, Borrelia burgdorferi, Neisseria gonorrhoeae, Campylobacter spp., Legionella pneumophila; anaerobic bacteria: Bacteroides fragilis.
The NATtrol BV Negative Control from PubMed Publications delivered next week by Gentaur to your Lab is the best reagent. The catalog number is NATBVNEG-BD and the price is 229 EUR.. ...
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Methane is metabolized principally by methanotrophs and methanogens in the global carbon cycle. Methanotrophs consume methane as the only source of carbon, while methanogens produce methane as a metabolic byproduct. Methylotrophs, which are microorganisms that can obtain energy for growth by oxidizing one-carbon compounds, such as methanol and methane, are situated between methanotrophs and methanogens. Methanogens can obtain energy for growth by converting a limited number of substrates to methane under anaerobic conditions. Three types of methanogenic pathways are known: CO2 to methane [MD:M00567], methanol to methane [MD:M00356], and acetate to methane [MD:M00357]. Methanogens use 2-mercaptoethanesulfonate (CoM; coenzyme M) as the terminal methyl carrier in methanogenesis and have four enzymes for CoM biosynthesis [MD:M00358]. Coenzyme B-Coenzyme M heterodisulfide reductase (Hdr), requiring for the final reaction steps of methanogenic pathway, is divided into two types: cytoplasmic HdrABC in ...
BLOT kit for the detection of specific IgG antibodies to the recombinant antigens of Bordetella pertussis and Bordetella parapertussis in human serum and plasma, for automated processing using the BlueDiver Instrument.
ID Q7WA84_BORPA Unreviewed; 113 AA. AC Q7WA84; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 08-MAY-2019, entry version 75. DE RecName: Full=Flagellar protein {ECO:0000256,RuleBase:RU362064}; GN Name=fliO {ECO:0000313,EMBL:CAE36803.1}; GN OrderedLocusNames=BPP1501 {ECO:0000313,EMBL:CAE36803.1}; OS Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253). OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Alcaligenaceae; Bordetella. OX NCBI_TaxID=257311 {ECO:0000313,Proteomes:UP000001421}; RN [1] {ECO:0000313,Proteomes:UP000001421} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=12822 / ATCC BAA-587 / NCTC 13253 RC {ECO:0000313,Proteomes:UP000001421}; RX PubMed=12910271; DOI=10.1038/ng1227; RA Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N., RA Harris D.E., Holden M.T., Churcher C.M., Bentley S.D., Mungall K.L., RA Cerdeno-Tarraga A.M., Temple L., James K., Harris B., Quail M.A., RA Achtman M., Atkin ...
ID Q7WA69_BORPA Unreviewed; 120 AA. AC Q7WA69; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 08-MAY-2019, entry version 72. DE SubName: Full=Putative flagellar protein {ECO:0000313,EMBL:CAE36820.1}; GN OrderedLocusNames=BPP1518 {ECO:0000313,EMBL:CAE36820.1}; OS Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253). OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Alcaligenaceae; Bordetella. OX NCBI_TaxID=257311 {ECO:0000313,Proteomes:UP000001421}; RN [1] {ECO:0000313,Proteomes:UP000001421} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=12822 / ATCC BAA-587 / NCTC 13253 RC {ECO:0000313,Proteomes:UP000001421}; RX PubMed=12910271; DOI=10.1038/ng1227; RA Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N., RA Harris D.E., Holden M.T., Churcher C.M., Bentley S.D., Mungall K.L., RA Cerdeno-Tarraga A.M., Temple L., James K., Harris B., Quail M.A., RA Achtman M., Atkin R., Baker S., Basham D., Bason N., ...
Definition : Molecular assay reagents intended to identify species of Bordetella, a genus of gram-negative coccobacillus bacteria, by detecting specific nucleic-acid information of the target bacteria. Some species of these bacteria may cause infections in the human respiratory tract, including whooping cough.. Entry Terms : Whooping Cough Diagnostic Reagents , Pertussis Diagnostic Reagents , Parapertussis Diagnostic Reagents , Bordetella Species Detection/Identification Reagents , Reagents, Molecular Assay, Infection, Bacteria, Bordetella Species. UMDC code : 21449 ...
CAN 152:516583 1-3 Pharmacology 9000-81-1 (Acetylcholinesterase); 9001-08-5 Role: BSU (Biological study, unclassified), BIOL (Biological study) (bivalent beta -carbolines as potential multitarget anti-alzheimer agents); 103800-21-1P; 1225056-56-3P; 1225056-70-1P; 1225056-71-2P; 1225056-72-3P; 1225056-73-4P; 1225056-74-5P; 1225056-75-6P Role: PAC (Pharmacological activity), RCT (Reactant), SPN (Synthetic preparation), THU (Therapeutic use), BIOL (Biological study), PREP (Preparation), USES (Uses), RACT (Reactant or reagent) (bivalent beta -carbolines as potential multitarget anti-alzheimer agents); 244-63-3 (9H-Pyrido[3,4-b]indole); 30684-42-5; 58982-28-8 (9H-Pyrido[3,4-b]indol-6-ol) Role: PAC (Pharmacological activity), RCT (Reactant), THU (Therapeutic use), BIOL (Biological study), USES (Uses), RACT (Reactant or reagent) (bivalent beta -carbolines as potential multitarget anti-alzheimer agents); 5667-11-8P; 53952-75-3P; 950993-91-6P; 1225056-47-2P; 1225056-48-3P; 1225056-49-4P; 1225056-50-7P; ...
ECDC is addressing the harmonisation and improvement of pertussis diagnosis for surveillance and outbreak detection/monitoring in order to assure quality and comparability of data. The guidance and protocol are intended for real-time PCR on DNA extracted from clinical specimens obtained from patients with suspected whooping cough (i.e. Bordetella pertussis or B. parapertussis). ...
ECDC is addressing the harmonisation and improvement of pertussis diagnosis for surveillance and outbreak detection/monitoring in order to assure quality and comparability of data. The guidance and protocol are intended for real-time PCR on DNA extracted from clinical specimens obtained from patients with suspected whooping cough (i.e. Bordetella pertussis or B. parapertussis). ...
Header: /usr/site/nrniv/simctrl/hoc/RCS/local.hoc,v 1.15 2003/02/13 15:32:06 billl Exp $ // // This file contains local modifications to nrnoc.hoc and default.hoc // // Users should not edit nrnoc.hoc or default.hoc. Any local // changes to these files should be made in this file. // ------------------------------------------------------------ //* MODIFICATIONS TO NRNOC.HOC // The procedures declared here will overwrite any duplicate // procedures in nrnoc.hoc. // ------------------------------------------------------------ //*MODIFICATIONS TO DEFAULT.HOC // // Vars added here may not be handled properly within nrnoc.hoc //------------------------------------------------------------ //** String defaults //** Simulation defaults long_dt = .001 // msec objref sfunc,tmpfile sfunc = hoc_sf_ // needed to use is_name() tmpfile = new File() // check for existence before opening a users local.hoc file proc write_comment () { tmpfile.aopen(index) tmpfile.printf(%s\n,$s1) tmpfile.close() } func asin ...
Using antisera raised against serotype 2 and 3 fimbrial subunits from Bordetella pertussis, serologically related polypeptides were detected in Bordetella bronchiseptica, Bordetella parapertussis and Bordetella avium strains. The two B. pertussis fimbrial subunits, and three of the serologically related B. bronchiseptica polypeptides, were shown to be very similar in amino ... read more acid composition and N-terminal amino acid sequence. Homology was observed between the N-termini of these polypeptides, and fimbrial subunits from Escherichia coli, Haemophilus influenzae and Proteus mirabilis. A synthetic oligonucleotide probe, derived from the N-terminal sequence of the B. pertussis serotype 2 fimbrial subunit, was used to identify fimbrial genes in genomic Southern blots. The results suggested the presence of multiple fimbrial subunit genes in B. pertussis, B. bronchiseptica and B. parapertussis. The DNA probe was used to clone one of the three tentative fimbrial subunit genes detected in B. ...
Bordetella pertussis is an aerobic gram-negative bacterial pathogen that causes the human respiratory disease whooping cough. Despite widespread vaccination, whooping cough is reemerging due to decreased vaccine efficacy. One of the hallmarks of infection is lymphocytosis, which is induced by the pertussis toxin. Lymphocytes such as CD4+ T cells navigate to infected tissues through surface-trafficking molecules, which are imprinted during their interaction with tissue-associated dendritic cells. We hypothesized that the pertussis toxin affects the imprinting process resulting in altered expression of trafficking molecules on CD4+ T cells. We tested this hypothesis using a mouse model of infection. Imprinting levels on CD4+ T cells were compared to Bordetella parapertussis, a related strain that lacks pertussis toxin. Our results indicated that 5 days post-infection, the percentage of lung dendritic cells increased and adopted a mature phenotype (displaying an increased capability to migrate and present
Pertussis toxin is coded by a multi-subunit protein complex. PCR assays focus on the promoter region of the pertussis toxin operon, which is well-characterized and is already used as a target for diagnostic PCR assays. This genetic region is not specific to B. pertussis as it can also be found in the genome of B. parapertussis and B. bronchiseptica. However, these other species contain mutations in their operon sequence, which prevent the expression of the actual toxin. These mutations provide a way to differentiate between the three species of Bordetella using melting temperatures in real-time PCR ...
Id: simctrl.hoc,v 1.14 2000/11/27 21:59:33 billl Exp $ // Graphic routines for neuremacs simulation control proc sim_panel () { xpanel(simname) xvarlabel(output_file) xbutton(Init, stdinit()) xbutton(Init & Run, run()) xbutton(Stop, stoprun=1) xbutton(Continue till Tstop, continueRun(tstop)) xvalue(Continue till, runStopAt, 1, {continueRun(runStopAt) stoprun=1}, 1, 1) xvalue(Continue for, runStopIn, 1, {continueRun(t + runStopIn) stoprun=1}, 1,1) xbutton(Single Step, steprun()) xvalue(Tstop, tstop, 1, tstop_changed(), 0, 1) graphmenu() sim_menu_bar() misc_menu_bar() xpanel() } proc misc_menu_bar() { xmenu(Miscellaneous) xbutton(Label Graphs, labelgrs()) xbutton(Label With String, labelwith()) xbutton(Label Panel, labelpanel()) xbutton(Parameterized Function, load_template(\FunctionFitter\) makefitter()) xmenu() } proc sim_menu_bar() { xmenu(Simulation Control) xbutton(File Vers, elisp(\sim-current-files\)) xbutton(File ...
Hello Id like to ask your help on improving my dps. Feels I should do better, but I cant find what Im missing... Ive been very lucky with drops, but especially on multitarget fights my fellow guild hunter does better job. I blame that on my.. eh, just messing things and dots up. But to get basics...
The Sanger Institute has been funded by the Wellcome Trust to sequence the genomes of Bordetella pertussis strain Tohama I, B. parapertussis strain 12822 and B. bronchiseptica strain RB50 in collaboration with Duncan Maskell and Andrew Preston of the Centre for Veterinary Science, Dept. of Clinical Veterinary medicine, The University of Cambridge. The sequences and analysis are described in: Parkhill et al (2003) Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. Nature Genetics 35 32-40 (DOI: 10.1038/Ng1227), and have been submitted to EMBL/GenBank with the accession numbers: BX470248 (B. pertussis), BX470249 (B. parapertussis) and BX470250 (B. bronchiseptica). The three sequenced Bordetella strains have been deposited with the ATCC and NCTC under the following accession numbers: Bordetella parapertussis 12822: ATCC BAA-587, NCTC 13253 Bordetella bronchiseptica RB50: ATCC BAA-588, NCTC 13252 Bordetella pertussis Tohama ...
The genus Bordetella consists of Gram-negative β-proteobacteria, including the three human pathogens Bordetella pertussis, Bordetella parapertussis an...
5] Binns, S. H., Corkill, J. E., Dawson, S., Gaskell, R. M., Hart, C. A., Kariuki, S., Osborn, A. M., Saunders, J. R., and Speakman, A. J. 1997. Characterization of antibiotic resistance plasmids from Bordetella bronchiseptica. Journal of Antimicrobial Chemotherapy. 40: 811-816. [[6] Appel J. G. M., Bemis, A. D., and Greisen, A. H. 1977. Pathogenesis of canine bordetellosis. The Journal of Infectious Diseases. 135: 753-762. [[7] Vanderzee, A, Mooi, F., Emben, J. V., and Musser, J. Molecular evolution and host adaptation of Bordetella spp.: phylogenetic analysis using multilocus enzyme electrophoresis and typing with three insertion sequences. 1997. Journal of Bacteriology. 179: 6609-6617. [[8] Roberts, M., and Stevenson, A. 2003. Use of Bordetella bronchiseptica and Bordetella pertussis as live vaccines and vectors for heterologous antigens. FEMS Immunology and Medical Microbiology. 37: 121-128. [[9] Arico, B. and Rappuoli, R. Bordetella parapertussis and Bordetella ...
Bordetella is a genus of small (0.2 - 0.7 µm), Gram-negative coccobacilli of the phylum Proteobacteria. Bordetella species, with the exception of B. petrii, are obligate aerobes, as well as highly fastidious, or difficult to culture. All species can infect humans. The first three species to be described (B. pertussis, B. parapertussis, B. bronchiseptica,); are sometimes referred to as the classical species. One of these (B. bronchiseptica) is also motile. B. pertussis and occasionally B. parapertussis cause pertussis or whooping cough in humans, and some B. parapertussis strains can colonise sheep. B. bronchiseptica rarely infects healthy humans, though disease in immunocompromised patients has been reported. B. bronchiseptica causes several diseases in other mammals, including kennel cough and atrophic rhinitis in dogs and pigs, respectively. Other members of the genus cause similar diseases in other mammals, and in birds (B. hinzii, B. avium). The Bordetella genus is named after Jules ...
The genus Bordetella comprises several bacterial species that colonize the respiratory tract of mammals. It includes B. pertussis, a human-restricted pathogen that is the causative agent of Whooping Cough. In contrast, the closely related species B. bronchiseptica colonizes a broad range of animals as well as immunocompromised humans. Recent metagenomic studies have identified known and novel bordetellae isolated from different environmental sources, providing a new perspective on their natural history. Using phylogenetic analysis, we have shown that human and animal pathogenic bordetellae have most likely evolved from ancestors that originated from soil and water. Our recent study found that B. bronchiseptica can evade amoebic predation and utilize Dictyostelium discoideum as an expansion and transmission vector, which suggests that the evolutionary pressure to evade the amoebic predator enabled the rise of bordetellae as respiratory pathogens. Interactions with amoeba may represent the starting point
Rachel M. Stenger, Martien C. M. Poelen, Ed E. Moret, Betsy Kuipers, Sven C. M. Bruijns, Peter Hoogerhout, Marcel Hijnen, Audrey J. King, Frits R. Mooi, Claire J. P. Boog, Cécile A. C. M. van Els ...
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Of the 10 identified species in the genus Bordetella, only four are of major medical significance. B. pertussis infects only humans and is the most important Bordetella species causing human disease. B. parapertussis causes an illness in humans that is similar to pertussis but is typically milder; co-infections with B. parapertussis and B. pertussis have been documented. With improved polymerase chain reaction (PCR) diagnostic methodology, up to 20% of patients with a pertussis-like syndrome have been found to be infected with B. holmesii, formerly thought to be an unusual cause of bacteremia. B. bronchiseptica is an important pathogen of domestic animals that causes kennel cough in dogs, atrophic rhinitis and pneumonia in pigs, and pneumonia in cats. Both respiratory infection and opportunistic infection due to B. bronchiseptica are occasionally reported in humans. B. petrii, B. hinzii, and B. ansorpii have been isolated from patients who are immunocompromised. ...
The determination of the genome sequences of B. pertussis, B. parapertussis, and B. bronchiseptica was completed and the sequences were reported in 2003 by Parkhill et al. (18). We utilized early (August 2001) assemblies of these genome sequences to search for PCR target sequences that might be specific to B. pertussis. Two regions with significant sequence divergence were identified and utilized for the design of the BP283 and BP485 real-time PCR assays. Notably, the diagnostic potential of the region used for the design of our BP485 assay was also predicted previously by others using microarray-based comparative genome hybridization (4). Similarly, previous work using representational difference analysis described the genome region encompassing the BP283 target sequence as being specific to B. pertussis (15). Both assays demonstrated excellent sensitivities and specificities when applied to clinical isolates and nasopharyngeal specimens. In contrast to the IS481 assay, the BP283 and BP485 ...
Bordetella are small Gram-negative coccobacilli, of which Bordetella pertussis is the most important human pathogen. It is the cause of whooping cough, which is one of the 10 leading causes of childhood death. Transmission of this highly infectious organism is primarily by aerosolized droplets.Clinical features-presentation varies with age, immunization and previous infection: (1) infants-apnoea, cyanosis, and paroxysmal cough; (2) nonimmunized children-cough, increasing in severity with distressing, repeated, forceful expirations followed by a gasping inhalation (the whoop); (3) children immunized in infancy-whooping, vomiting, sputum production; (4) adults-cough, post-tussive vomiting. Atypical mild illness is common. Complications include pneumonia, pulmonary hypertension, seizures and encephalopathy. Most deaths occur in those less than 2 months old....
When and how often laboratory tests are done may depend on many factors. The timing of laboratory tests may rely on the results or completion of other tests, procedures, or treatments. Lab tests may be performed immediately in an emergency, or tests may be delayed as a condition is treated or monitored. A test may be suggested or become necessary when certain signs or symptoms appear. Due to changes in the way your body naturally functions through the course of a day, lab tests may need to be performed at a certain time of day. If you have prepared for a test by changing your food or fluid intake, lab tests may be timed in accordance with those changes. Timing of tests may be based on increased and decreased levels of medications, drugs or other substances in the body. The age or gender of the person being tested may affect when and how often a lab test is required. Chronic or progressive conditions may need ongoing monitoring through the use of lab tests. Conditions that worsen and improve may ...
Cologuard, a noninvasive multitarget stool screening test for CRC, has been found to have a sensitivity for cancer equal to colonoscopy. But questions remain as to where the test fits into the CRC screening algorithm.
... the herd is never protected, because, at any one point in time, there are very large portions of the herd that are not immune, because either the vaccine-induced immunity did not take, or it waned.
Bordetella bronchiseptica ATCC ® BAA-588D-5™ Designation: Genomic DNA from Bordetella bronchiseptica strain RB50 TypeStrain=False Application:
Nobivac Feline-Bb is for the intranasal vaccination of healthy kittens and cats for prevention of disease caused by Bordetella bronchiseptica. B. bronchiseptica acts as a primary or secondary pathogen in feline respiratory disease.
We report the repeated isolation of Bordetella petrii in the sputum of a 79-year-old female patient with diffuse bronchiectasis and persistence of the bacterium for >1 year. The patient was first hospitalized due to dyspnea, which developed into seve ...
Bordetella Vaccines - Bordetella vaccines will ensure your pet doesnt come down with kennel cough. Learn more about bordetella vaccines and treatments.
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Assignment 1. Select a topic from a list of emerging or reemerging infectious diseases (also found in module 3). 2. Provide the clinical name of the disease,
Viayna, E, Sola I, Bartolini M, De Simone A, Tapia-Rojas C, Serrano FG, Sabate R, Juarez-Jimenez J, Perez B, Luque FJ et al.. 2014. Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents. Journal of Medicinal Chemistry. 57 ...
"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica". ...
2003). "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella ... and Bordetella. Achtman was one of the inventors of multilocus sequence typing. His research has been funded by the ...
2003). "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella ...
Bordetella pertussis. Bordetella bronchiseptica and Bordetella parapertussis, also able to cause pertussis-like symptoms, also ... Vaccination against Bordetella pertussis is used in infancy to prevent whooping cough. The recent switch from whole-cell ... Adenylate cyclase toxin is a virulence factor produced by some members of the genus Bordetella. Together with the pertussis ... Differences between the toxins of different Bordetella species are mainly in the calcium-binding domain. The toxin is secreted ...
... of modified Bordet-Gengou and modified Regan-Lowe media for the isolation of Bordetella pertussis and Bordetella parapertussis ... has replaced Bordet-Gengou medium as the medium of choice for routine Bordetella pertussis incubation. Bordetella bacteria were ... Bordet-Gengou agar is a type of agar plate optimized to isolate Bordetella, containing blood, potato extract, and glycerol, ... ISBN 0-9631172-1-1. BD Bordet Gengou Agar with 15% Sheep Blood (product insert also describing Bordetella Agar with Charcoal) ...
... of modified Bordet-Gengou and modified Regan-Lowe media for the isolation of Bordetella pertussis and Bordetella parapertussis ...
Bordetella parapertussis shows the most similarity to B. pertussis and was therefore used for research determining the role of ... Rats infected with B. parapertussis or a PT-deficient mutant of B. pertussis did not show this symptom; neither of these two ... One difference between the different species of Bordetella is that B. pertussis produces PT and the other species do not. ... Bagley K, Abdelwahab S, Tuskan R, Fouts T, Lewis G (2002). "Pertussis toxin and the adenylate cyclase toxin from Bordetella ...
2003). "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella ... and Clinical Manifestations of Respiratory Infections Due to Bordetella pertussis and Other Bordetella Subspecies". Clinical ... 1991). "Effects of Bordetella pertussis infection on human respiratory epithelium in vivo and in vitro". Infection and Immunity ... Luker, K. E.; Collier, J. L.; Kolodziej, E. W.; Marshall, G. R.; Goldman, W. E. (1993). "Bordetella pertussis Tracheal ...
The three most common species of Bordetella are B. pertussis, B. parapertussis and B. bronchiseptica. These species are known ... The most thoroughly studied of the Bordetella species are B. bronchiseptica, B. pertussis and B. parapertussis, and the ... B. pertussis and occasionally B. parapertussis cause pertussis or whooping cough in humans, and some B. parapertussis strains ... After 42 days, the dogs were exposed to Bordetella bronchiseptica. This study determined that the live intranasal Bordetella ...
2003). "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella ... The genus Bordetella contains nine species: B. pertussis B. parapertussis, B. bronchiseptica, B. avium, B. hinzii, B. holmesii ... B. pertussis, B. parapertussis and B. bronchiseptica form a closely related phylogenetical group. B. parapertussis causes a ... Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus of the genus Bordetella, and the ...
B. pertussis and B. parapertussis are respiratory pathogens that cause pertussis. B. bronchiseptica and B. avium are ... Bordetella endotoxins are unique to the genus, species, and strain. B. trematum is the only Bordetella species with a semirough ... It is unique in being oxidase negative, since all other species of Bordetella are oxidase positive. Bordetella trematum may be ... Bordetella species typically infect the respiratory tracts of humans, but B. trematum has never been isolated from a human or ...
... is a small Gram-negative bacterium of the genus Bordetella that is adapted to colonise the mammalian ... Wolfe D, Goebel E, Bjornstad O, Restif O, Harvil E (2007). "The O Antigen Enables Bordetella parapertussis To Avoid Bordetella ... "Clinical characteristics of illness caused by Bordetella parapertussis compared with illness caused by Bordetella pertussis". ... Type strain of Bordetella parapertussis at BacDive - the Bacterial Diversity Metadatabase v t e. ...
... parapertussis. Unlike B. pertussis, B. bronchiseptica is generally resistant to macrolide antibiotics. It is also generally ... Bordetella bronchiseptica is a small, gram-negative, rod-shaped bacterium of the genus Bordetella. It can cause infectious ... Genetic sequences of the Bordetella bronchiseptica complex (Sanger Institute) Type strain of Bordetella bronchiseptica at ... Hewlett, EL (1995). "Bordetella species." In: Principles and Practice of Infectious Diseases (Mandel, GL, Bennett, JE, Dolin, R ...
Bordetella bronchiseptica MeSH B03.660.075.027.075.590 - Bordetella parapertussis MeSH B03.660.075.027.075.600 - Bordetella ... Bordetella parapertussis MeSH B03.440.400.425.117.075.550 - Bordetella pertussis MeSH B03.440.400.425.117.800 - Taylorella MeSH ... Bordetella MeSH B03.440.400.425.117.075.099 - Bordetella avium MeSH B03.440.400.425.117.075.200 - Bordetella bronchiseptica ... Bordetella MeSH B03.660.075.027.075.024 - Bordetella avium MeSH B03.660.075.027.075.050 - ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
... as well as Bordetella pertussis which causes whooping cough. Other members of the class can infect plants, such as Burkholderia ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX−). Lac+. *Klebsiella pneumoniae * ...
Bordetella pertussis/Bordetella parapertussis *Pertussis. γ. Enterobacteriales. (OX-). Lac+. *Klebsiella pneumoniae * ...
Bordetella parapertussis (Pertussis) ...
Bordetella-Clinical Manifestations. In: Barron's Medical Microbiology (4th ed.). Univ of Texas Medical Branch. ISBN 0-9631172-1 ... A similar, milder disease is caused by B. parapertussis.[37]. PreventionEdit. The primary method of prevention for pertussis is ... and Clinical Manifestations of Respiratory Infections Due to Bordetella pertussis and Other Bordetella Subspecies". Clin ... Pertussis is caused by the bacterium Bordetella pertussis.[4] It is an airborne disease which spreads easily through the coughs ...
Bordetella parapertussis (Pertussis) ...
Pertussis is caused by the bacterium Bordetella pertussis. It is spread easily through the coughs and sneezes of an infected ... A similar, milder disease is caused by B. parapertussis. The primary method of prevention for pertussis is vaccination. ... Pertussis is caused by the bacterium Bordetella pertussis. It is an airborne disease (through droplets) that spreads easily ...
Bordetella parapertussis is a small Gram-negative bacterium of the genus Bordetella that is adapted to colonise the mammalian ... Wolfe D, Goebel E, Bjornstad O, Restif O, Harvil E (2007). "The O Antigen Enables Bordetella parapertussis To Avoid Bordetella ... "Clinical characteristics of illness caused by Bordetella parapertussis compared with illness caused by Bordetella pertussis". ... Type strain of Bordetella parapertussis at BacDive - the Bacterial Diversity Metadatabase v t e. ...
Taxonomy - Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253) Basket 0 ... Bordetella parapertussis 12822. ›Bordetella parapertussis str. 12822. ›Bordetella parapertussis strain 12822. Rank i. - ... Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253). Taxonomy navigation. › Bordetella parapertussis ...
Genomic DNA from Bordetella parapertussis Strain 522 TypeStrain=True Application: ... Bordetella parapertussis ATCC 15311 16S rRNA, partial sequence. Nucleotide (GenBank) : X68368 B.parapertussis gene for 23S ... Genomic DNA from Bordetella parapertussis Strain 522 [ATCC® 15311™] Biosafety Level 1 Biosafety classification is based on U.S ... Bordetella parapertussis (Eldering and Kendrick) Moreno-Lopez (ATCC® 15311D-5™) Strain Designations: Genomic DNA from ...
Genomic DNA from Bordetella parapertussis Strain 522 TypeStrain=True Application: ... Bordetella parapertussis ATCC 15311 16S rRNA, partial sequence. Nucleotide (GenBank) : X68368 B.parapertussis gene for 23S ... Bordetella parapertussis (Eldering and Kendrick) Moreno-Lopez ATCC® 15311D-5™ dried At least 5 µg in 1X TE buffer. OD260/OD280 ... Genomic DNA from Bordetella parapertussis Strain 522 [ATCC® 15311™] Biosafety Level 1 Biosafety classification is based on U.S ...
Methane metabolism - Bordetella parapertussis Bpp5 [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show ...
... parapertussis exposed to hyperimmune and pre-colostrum porcine serum was examined. Viable cell numbers (cfu/ml) of the B. ... The viability of four strains of Bordetella bronchiseptica, two strains of B. pertussis and one strain of B. ... The viability of four strains of Bordetella bronchiseptica, two strains of B. pertussis and one strain of B. parapertussis ... Serum sensitivity and lipopolysaccharide characteristics in Bordetella bronchiseptica, B. pertussis and B. parapertussis J Med ...
Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are closely related Gram-negative beta- ... Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.. ... B. parapertussis can also cause whooping cough, and B. bronchiseptica causes chronic respiratory infections in a wide range of ... We sequenced the genomes of B. bronchiseptica RB50 (5,338,400 bp; 5,007 predicted genes), B. parapertussis 12822 (4,773,551 bp ...
Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes.. B Aricò, R ... Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes.. B Aricò, R ... Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes.. B Aricò, R ... Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes. Message Subject ...
X-Ray Crystal Structure of Protein BPP1347 from Bordetella parapertussis. Northeast Structural Genomics Consortium Target BoR27 ... Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253). N/A. Find proteins for Q7WAM7 (Bordetella parapertussis ( ... X-Ray Crystal Structure of Protein BPP1347 from Bordetella parapertussis. Northeast Structural Genomics Consortium Target BoR27 ... Crystal Structure of the Hypothetical Protein BPP1347 from Bordetella parapertussis, Northeast Structural Genomics Target BoR27 ...
Solution structure of protein BPP2914 from Bordetella parapertussis. Northeast Structural Genomics Consortium target BpR206 ... Solution structure of protein BPP2914 from Bordetella parapertussis. Northeast Structural Genomics Consortium target BpR206. * ...
Bordetella bronchiseptica OSU553. Bordetella pertussis. Bordetella pertussis 2356847. Bordetella pertussis H921. Bordetella ... Bordetella bronchiseptica OSU553. Bordetella pertussis. Bordetella pertussis 2356847. Bordetella pertussis H921. Bordetella ... sp,Q7W671,PIMT_BORPA Protein-L-isoaspartate O-methyltransferase OS=Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC ... Bordetella pertussis (strain ATCC 9797 / DSM 5571 / NCTC 10739 / 18323). Bordetella pertussis B1920. And more. 259. UniRef90_ ...
... including Bordetella parapertussis and Bordetella holmesii (16), although B. parapertussis infections are usually less severe ( ... Discrimination of Bordetella parapertussis and Bordetella pertussis organisms from clinical isolates by PCR using biotin- ... Whooping cough caused by Bordetella pertussis and Bordetella parapertussis in an immunized population. JAMA 280:635-637. ... PCR is increasingly being used as a diagnostic test for the detection of Bordetella pertussis and Bordetella parapertussis DNA ...
... the toxin promoter region and Bordetella parapertussis insertion sequence IS1001 were designed. PCR assays were capable of ... Novel real-time PCR assays targeting the Bordetella pertussis insertion sequence IS481, ... Real-time PCR-based detection of Bordetella pertussis and Bordetella parapertussis in an Irish paediatric population J Med ... Seven specimens (0.5 %) were B. parapertussis culture positive and 10 (0.8 %) were B. parapertussis PCR positive, with all ...
The efficacy of a whole cell pertussis vaccine and fimbriae against Bordetella pertussis and Bordetella parapertussis ... The efficacy of a whole cell pertussis vaccine and fimbriae against Bordetella pertussis and Bordetella parapertussis ...
View Bordetella parapertussis E838, titered (1 mL) 0801644 from our online collection of viruses, microorganisms, and other ...
Creative Biolabs offers the best Recombinant Bordetella Parapertussis infA1 Protein (aa 1-72), which is useful for vaccine ... Recombinant Bordetella Parapertussis infA1 Protein (aa 1-72) (VAng-Lsx4456). CAT. Size. Price. Quantity. ... Bordetella is a genus of small (0.2 - 0.7 µm), Gram-negative coccobacilli of the phylum Proteobacteria. Bordetella species, ... The Bordetella genus is named after Jules Bordet. All species can infect humans. The first three species to be described (B. ...
A rapid real-time multiplex PCR assay for detecting and differentiating Bordetella pertussis and Bordetella parapertussis in ... N2 - A rapid real-time multiplex PCR assay for detecting and differentiating Bordetella pertussis and Bordetella parapertussis ... AB - A rapid real-time multiplex PCR assay for detecting and differentiating Bordetella pertussis and Bordetella parapertussis ... T1 - Multiplex lightcycler PCR assay for detection and differentiation of Bordetella pertussis and Bordetella parapertussis in ...
Whooping cough due to Bordetella parapertussis with pneumonia. 2016 2017 2018 Billable/Specific Code *A37.11 is a billable/ ... Short description: Whooping cough due to Bordetella parapertussis w pneumonia. *The 2018 edition of ICD-10-CM A37.11 became ... Whooping cough due to Bordetella parapertussis without pneumonia. 2016 2017 2018 Billable/Specific Code ... Whooping cough due to bordetella with pneumonia. ICD-10-CM A37.11 is grouped within Diagnostic Related Group(s) (MS-DRG v35.0): ...
n. pertussis, the specific epithet of Bordetella pertussis; N.L. gen. n. parapertussis, resembling Bordetella pertussis ... Parent taxon: Bordetella Moreno-López 1952 (Approved Lists 1980) Assigned by: Moreno-Lopez M. El genero Bordetella. ... Name: Bordetella parapertussis (Eldering and Kendrick 1938) Moreno-López 1952 (Approved Lists 1980) ... lpsn.dsmz.de/species/bordetella-parapertussis. Copy to clipboard. Link copied to clipboard ...
Inefficient toll-like receptor-4 stimulation enables Bordetella parapertussis to avoid host immunity. PloS one. 2009 Jan 26;4(1 ... Fingerprint Dive into the research topics of Inefficient toll-like receptor-4 stimulation enables Bordetella parapertussis to ... Inefficient toll-like receptor-4 stimulation enables Bordetella parapertussis to avoid host immunity. / Wolfe, Daniel N.; ... Wolfe, DN, Buboltz, AM & Harvill, ET 2009, Inefficient toll-like receptor-4 stimulation enables Bordetella parapertussis to ...
Bordetella parapertussis, , , ... World Heritage Encyclopedia, the aggregation of the largest online encyclopedias available, ... Bordetella parapertussis is a small Gram-negative bacterium of the genus Bordetella that is adapted to colonise the mammalian ... Wolfe D, Goebel E, Bjornstad O, Restif O, Harvil E (2007). "The O Antigen Enables Bordetella parapertussis To Avoid Bordetella ... parapertussis, however, because the O-antigen is found only on B. parapertussis. This antigen protects B. parapertussis against ...
"Bordetella parapertussis 12822". Graphical representation of Chlorocyclohexane and chlorobenzene degradation (Bordetella ... parapertussis 12822) (PNG image hosted by the Kyoto Encyclopedia of Genes and Genomes, KEGG). ...
ICD-10 A37.11 is whooping cough due to bordetella parapertussis with pneumonia (A3711). This code is grouped under diagnosis ... Whooping cough due to Bordetella parapertussis w pneumonia. Long Description: Whooping cough due to Bordetella parapertussis ... A37.11 WHOOPING COUGH DUE TO BORDETELLA PARAPERTUSSIS W PNEUMONIA Home > ICD-10 List > Certain infectious and parasitic ... Whooping cough due to other Bordetella species without pneumonia. 9. A37.81. Whooping cough due to other Bordetella species ...
span,,b,Purpose.,/b, Human-adapted ,i,Bordetella parapertussis,/i, is one of the causative agents of whooping cough; however, ... A novel multilocus variable-number tandem repeat analysis for Bordetella parapertussis Kazunari Kamachi 1 , Nao Otsuka 1 , Rei ... A novel multilocus variable-number tandem repeat analysis for Bordetella parapertussis Kazunari Kamachi et al. J Med Microbiol. ... Purpose. Human-adapted Bordetella parapertussis is one of the causative agents of whooping cough; however, there are currently ...
... from Bordetella parapertussis Bpp5. Plus protein sequence and external database links. ... Domain assignment for gi,410474031,ref,YP_006897312.1, from Bordetella parapertussis Bpp5. Domain architecture ... GntR family transcriptional regulator [Bordetella parapertussis Bpp5]. Sequence. ...
Diagenode Diagnostics specialises in real-time pcr kits for detection of Bordetella pertussis and Bordetella parapertussis ... Bordetella pertussis. FAM 520 nm. Insertion sequence (IS) 481. 250 µL. Bordetella parapertussis. Yellow dye 549 nm. Insertion ... SDS-DDGR-10-EN-v01-Bordetella-pertussis-parapertussis V01. EN. Download. SDS. DDGR-10-L100. SDS-DDGR-10-FR-v01-Bordetella- ... Among the nine species of Bordetella identified to date, only four members (B. pertussis, B. parapertussis, B. holmesii, B. ...
C-terminal domain superfamily in Bordetella parapertussis 12822. Domain architectures illustrate each occurrence of the ... 1 domain combinations include a Methylesterase CheB, C-terminal domain domain in Bordetella parapertussis 12822. With a total ... Home > Genomes > Bordetella parapertussis 12822 > Methylesterase CheB, C-terminal domain > Domain combinations ... Domain combinations for Methylesterase CheB, C-terminal domain superfamily in Bordetella parapertussis 12822. ...
A37.10 is a billable code used to specify a medical diagnosis of whooping cough due to bordetella parapertussis without ... Whooping cough due to Bordetella parapertussis w/o pneumonia. Long Description:. Whooping cough due to Bordetella parapertussis ... Infection due to Bordetella parapertussis. Diagnostic Related Groups. The ICD-10 code A37.10 is grouped in the following groups ... A37.10 is a billable code used to specify a medical diagnosis of whooping cough due to bordetella parapertussis without ...
Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. B. pertussis, and occasionally B. parapertussis, ... Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.. ... Bordetella parapertussis 12822: ATCC BAA-587, NCTC 13253 Bordetella bronchiseptica RB50: ATCC BAA-588, NCTC 13252 Bordetella ... Bordetella parapertussis and Bordetella bronchiseptica. Nature Genetics 35 32-40 (DOI: 10.1038/Ng1227), and have been submitted ...
Bordetella bronchiseptica B. holmesii. Bordetella holmesii B. parapertussis. Bordetella parapertussis. B. pertussis. Bordetella ...
  • Bordetella parapertussis is a small Gram-negative bacterium of the genus Bordetella that is adapted to colonise the mammalian respiratory tract. (wikipedia.org)
  • Bordetella is a genus of small (0.2 - 0.7 µm), Gram-negative coccobacilli of the phylum Proteobacteria. (creative-biolabs.com)
  • The Bordetella genus is named after Jules Bordet. (creative-biolabs.com)
  • Bordetella is a Gram-negative encapsulated coccobacillus of the genus Bordetella, and the causative agent of the respiratory infection named pertussis or whooping cough. (diagenodediagnostics.com)
  • There are eight species in the genus Bordetella , some of these species are known to also harbor the insertion sequences IS481 and IS1001, the targets for the Eragen pertussis and parapertussis primers respectively (and always harbored by pertussis and parapertussis) . (childrenshospitaloakland.org)
  • The Bordetella genus contains at the moment a dozen species, of which at least five are responsible for respiratory diseases in humans and/or animals. (mdpi.com)
  • Immunity derived from B. pertussis does not protect against infection by B. parapertussis, however, because the O-antigen is found only on B. parapertussis. (wikipedia.org)
  • The incidence of infection with B. parapertussis is low while the incidence of RSV infection in infants suspected of having pertussis is high, with a similar age distribution to B. pertussis infection. (nih.gov)
  • Bordetella bronchiseptica and B. pertussis stimulate robust TLR4 responses that are required to control the infection, but a close relative, B. parapertussis, poorly stimulates this receptor, and TLR4 deficiency does not affect its course of infection. (elsevier.com)
  • In a mouse model of infection, B. parapertussis grew rapidly in the lungs, but no measurable increase in TLR4-mediated cytokine, chemokine, or leukocyte responses were observed over the first few days of infection. (elsevier.com)
  • As we have previously shown, B. parapertussis grows efficiently during the first week of infection even in animals passively immunized with antibodies. (elsevier.com)
  • The ICD-10-CM code A37.10 might also be used to specify conditions or terms like infection due to bordetella or infection due to bordetella parapertussis. (icdlist.com)
  • Our data raise the possibility that widespread aP vaccination can create hosts more susceptible to B. parapertussis infection. (crazzfiles.com)
  • A method of detecting Bordetella pertussis and Bordetella parapertussis infection is provided. (edu.au)
  • If positive, hybridization to a Bordetella pertussis-specific probe and/or a Bordetella parapertussis-specific probe is used to determine whether the porin gene fragment is indicative of Bordetella pertussis and/or Bordetella parapertussis infection. (edu.au)
  • To classify the study population in the Argentinian National Health Surveillance System framework, determine the proportion of infection by Bordetella pertussis and Bordetella parapertussis , and identify factors associated with the cases of suspected whooping cough attended to in the city of Mar del Plata and its outskirts during the period 2011- 2015. (bvsalud.org)
  • This is a group of tests that are performed to detect and diagnose a Bordetella pertussis infection. (labtestsonline.org.au)
  • Pertussis, commonly called whooping cough, is a respiratory infection caused by the bacteria Bordetella pertussis . (labtestsonline.org)
  • Pertussis tests are used to detect and diagnose a Bordetella pertussis infection, commonly known as whooping cough, a highly contagious infection of the respiratory tract. (labcorp.com)
  • As part of this project ECDC is publishing two complementary guidance and protocols on Bordetella pertussis , the first on serological diagnosis of human infection and the second on the use of RT-PCR (real time polymerase chain reaction) for diagnosis of bordetella infections. (europa.eu)
  • The guidance and protocol is intended for real-time PCR on DNA extracted from clinical specimens obtained from patients with suspected whooping cough (i.e. infection with Bordetella pertussis or B. parapertussis ). (europa.eu)
  • The Sanger Institute has been funded by the Wellcome Trust to sequence the genomes of Bordetella pertussis strain Tohama I, B. parapertussis strain 12822 and B. bronchiseptica strain RB50 in collaboration with Duncan Maskell and Andrew Preston of the Centre for Veterinary Science, Dept. of Clinical Veterinary medicine, The University of Cambridge. (sanger.ac.uk)
  • CC Bordetella parapertussis 12822, complete genome. (univ-lyon1.fr)
  • This antigen protects B. parapertussis against antibodies specific to B. pertussis, so the bacteria are free to colonize the host's lungs without being subject to attack by previous antibodies. (wikipedia.org)
  • Pertussis-like symptoms are also caused by related species of bacteria, including Bordetella parapertussis and Bordetella holmesii ( 16 ), although B. parapertussis infections are usually less severe ( 8 ). (asm.org)
  • It is caused by the Bordetella pertussis bacteria. (medlineplus.gov)
  • An infectious condition caused by the bacteria Bordetella pertussis. (rightdiagnosis.com)
  • Bordetella bacteria are respiratory pathogens. (accessscience.com)
  • B. parapertussis can also cause whooping cough, and B. bronchiseptica causes chronic respiratory infections in a wide range of animals. (nih.gov)
  • The real-time PCR designed for B. pertussis and B. parapertussis provides sensitive and specific diagnosis of B. pertussis and B. parapertussis infections and is therefore suitable for implementation in the diagnostic laboratory. (asm.org)
  • The efficacy of a whole cell pertussis vaccine and fimbriae against Bordetella pertussis and Bordetella parapertussis infections in a respiratory mouse model. (rivm.nl)
  • Among the nine species of Bordetella identified to date, only four members ( B. pertussis, B. parapertussis, B. holmesii, B. bronchiseptica ) have been associated with respiratory infections in humans and others mammals. (diagenodediagnostics.com)
  • Three groups of monoclonal antibodies (mAbs) were produced that would be useful for immunochemical typing and diagnosis of infections due to Bordetella species, and for the structural analysis of their lipopolysaccharides. (microbiologyresearch.org)
  • Although Bordetella pertussis is considered the main causative agent of whooping cough in humans, Bordetella parapertussis infections are not uncommon. (crazzfiles.com)
  • B. parapertussis CFUs were higher in aP-relative to sham-vaccinated hosts regardless of whether infections were single or mixed. (crazzfiles.com)
  • The rationale to design and employ vaccines that target only B. pertussis stems from the assumption that B. parapertussis infections are not widely prevalent. (crazzfiles.com)
  • Primary infections with either B. pertussis or Bordetella parapertussis stimulated a vigorous antibody response to ACT. (greenmedinfo.com)
  • Bordetella holmesii can cause invasive infections but can also be isolated from the respiratory tract of patients with whooping-cough like symptoms. (mdpi.com)
  • Bordetella bronchiseptica causes infections that are typically chronic and often asymptomatic in a broad range of animals ( 21 ). (asm.org)
  • Respiratory infections may also be caused by bacterial pathogens, including Bordetella pertussis , Bordetella parapertussis , Chlamydophila pneumoniae , and Mycoplasmoides pneumoniae (previously Mycoplasma pneumoniae ). (mayocliniclabs.com)
  • Cherry JD, Heininger U. Pertussis and other Bordetella Infections. (medscape.com)
  • The real-time PCR for IS 481 detects both B. pertussis and Bordetella holmesii , and the real-time PCR for IS 1001 detects both B. parapertussis and B. holmesii . (asm.org)
  • The sensitivity was 1 to 10 CFU/ml for B. pertussis , 10 CFU/ml for B. parapertussis , and 10 CFU/ml for B. holmesii in both assays. (asm.org)
  • Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. (nih.gov)
  • Four highly polymorphic variable number tandem repeat (VNTR) loci in the B. parapertussis genome were selected and amplified by multiplex PCR. (cdc.gov)
  • The sequences and analysis are described in: Parkhill et al (2003) Comparative analysis of the genome sequences of Bordetella pertussis , Bordetella parapertussis and Bordetella bronchiseptica . (sanger.ac.uk)
  • B. pertussis primers target a 51 bp fragment in the multicopy insertion sequence IS481 (~240 copies/genome), and B. parapertussis primers target a 70 bp region in IS1001 (~20 copies/genome). (childrenshospitaloakland.org)
  • It is believed that the species diverged 3.5 million years ago through decay of the Bordetella brochiseptica genome, as seen through a large-scale gene loss of the two subsequent species. (kenyon.edu)
  • The discriminatory power of MLVA was evaluated with three laboratory reference strains and 50 human isolates of B. parapertussis . (cdc.gov)
  • Multiplex PCR-based MLVA characterized 53 B. parapertussis reference strains and isolates into 25 MLVA types and the Simpson diversity index was 0.91 (95 % confidence interval, 0.86-0.97). (cdc.gov)
  • Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015. (greenmedinfo.com)
  • This trait was only described in B. pertussis and B. parapertussis strains, as well as in B. petrii isolates by the past. (mdpi.com)
  • In the United States, the proportion of Bordetella pertussis isolates lacking pertactin, a component of acellular pertussis vaccines, increased from 14% in 2010 to 85% in 2012. (aappublications.org)
  • High prevalence of pertactin (PRN)-deficient Bordetella pertussis isolates has been found in these countries. (eurosurveillance.org)
  • Pertussis toxin, the major virulence factor of Bordetella pertussis, is not produced by the closely related species Bordetella parapertussis and Bordetella bronchiseptica. (asm.org)
  • AF157361 Bordetella parapertussis strain ATCC 15311 pertussis toxin gene, promotor region. (atcc.org)
  • U04949 Bordetella parapertussis ATCC 15311 16S rRNA, partial sequence. (atcc.org)
  • For example, Bordetella holmseii (ATCC strain 51541) harbors multiple copies of an IS481-like element and three to five copies of an IS1001-like element that shares only 87% sequence similarity [1]. (childrenshospitaloakland.org)
  • Bordetella pertussis is the causative agent of whooping cough (pertussis), an infectious disease that occurs worldwide with a high prevalence among young unvaccinated infants ( 1 , 27 ) and recently has reemerged in highly vaccinated populations ( 10 ). (asm.org)
  • Bordetella pertussis , the causative agent of whooping cough, is a strict human pathogen with no known animal or environmental reservoir. (asm.org)
  • The viability of four strains of Bordetella bronchiseptica, two strains of B. pertussis and one strain of B. parapertussis exposed to hyperimmune and pre-colostrum porcine serum was examined. (nih.gov)
  • In contrast, smooth B. bronchiseptica strains and the B. parapertussis strain showed no significant decrease in viable cell numbers after the same treatment. (nih.gov)
  • Analysis of silver-stained SDS-PAGE profiles of lipopolysaccharide (LPS) extracted from the bacterial cells indicated that the smooth strains of B. bronchiseptica and the B. parapertussis strain possessed high mol. (nih.gov)
  • Phylogenetic analyses have shown that B. parapertussis strains isolated from humans are distinct from those isolated from sheep, and there is little or no transmission between the two reservoirs (sheep and human). (sanger.ac.uk)
  • The Sanger Institute has completed a project to sequence further strains within the Bordetella bronchiseptica complex to investigate the evolutionary history and host tropism differences within this group of organsims. (sanger.ac.uk)
  • Bordetella species, with the exception of B. petrii , are obligate aerobes, as well as highly fastidious, or difficult to culture. (creative-biolabs.com)
  • Bordetella petrii sp. (straininfo.net)
  • A37.10 is a billable code used to specify a medical diagnosis of whooping cough due to bordetella parapertussis without pneumonia. (icdlist.com)
  • Indeed, the vast majority of whooping cough studies do not attempt to identify B. parapertussis because differential diagnosis does not affect clinical management and this probably leads to under-reporting. (crazzfiles.com)
  • However, when differential diagnosis has been carried out, B. parapertussis was found to comprise between 2 and 36 per cent of cases ( Watanabe & Nagai 2004 ) and, in one study, to constitute the major aetiological agent ( Borska & Simkovicova 1972 ). (crazzfiles.com)
  • Seven specimens (0.5 %) were B. parapertussis culture positive and 10 (0.8 %) were B. parapertussis PCR positive, with all culture-positive samples yielding PCR-positive results. (nih.gov)
  • Of the specimens, 12 were positive (9 B. pertussis and 3 B. parapertussis) and 68 specimens were negative by all methods. (elsevier.com)
  • All of these characteristics represent a significant improvement in the detection of B. pertussis and B. parapertussis in nasopharyngeal specimens. (elsevier.com)
  • Research laboratories can identify B. pertussis and B. parapertussis from specimens such as nasopharyngeal swabs (NPS) using a sample to answer platform. (luminexcorp.com)
  • Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are closely related Gram-negative beta-proteobacteria that colonize the respiratory tracts of mammals. (nih.gov)
  • Novel real-time PCR assays targeting the Bordetella pertussis insertion sequence IS481, the toxin promoter region and Bordetella parapertussis insertion sequence IS1001 were designed. (nih.gov)
  • Even though Bordetella species are closely related at the nucleotide sequence level, they differ in several respects, such as severity of disease and host range specificity. (asm.org)
  • 033.8, Whooping cough due to other specified organism, which also includes Bordetella bronchiseptica . (fortherecordmag.com)
  • Bordetella pertussis is the causative agent of pertussis, or whooping cough, a disease characterized by prolonged cough that may be associated with an inspiratory whoop and post-tussive vomiting. (mayocliniclabs.com)
  • Bordetella pertussis and parapertussis are closely related gram-negative coccobacilli responsible for cyclical outbreaks of a whooping cough occurring every three to five years. (childrenshospitaloakland.org)
  • Bordetella bronchiseptica is mostly closely related to Bordetella pertussis and Bordetella parapertussis, both of which is believed to have risen originally from Bordtella bronchiseptica. (kenyon.edu)
  • A rapid real-time multiplex PCR assay for detecting and differentiating Bordetella pertussis and Bordetella parapertussis in nasopharyngeal swabs was developed. (elsevier.com)
  • Results for Bordetella culture and/or direct fluorescent antibody testing and a second LightCycler PCR assay (target, pertussis toxin gene) were compared to results of the LC-PCR-IS assay for 111 nasopharyngeal swabs submitted for pertussis testing. (elsevier.com)
  • The method includes amplification of a Bordetella porin gene fragment from a sample such as a human nasopharyngeal aspirate using a Bordetella-specific primer, a Bordetella pertussis-specific primer and a Bordetella parapertussis-specific primer. (edu.au)
  • They also provided nasopharyngeal aspirates or, in a few centers, swab samples for culture and/or PCR detection of Bordetella pertussis and an acute blood sample for detection of anti-PT immunoglobulin G (IgG). (asm.org)
  • Many of the mutations common to B. parapertussis and B. bronchiseptica involve the promoter region, which becomes very inefficient. (asm.org)
  • B. pertussis only infects humans while B. parapertussis infects both humans and sheep. (sanger.ac.uk)
  • Bordetella bronchiseptica'' is a minute, gram-negative rod-shaped coccobacillus about .5-1 micrometers in diameter and 5 micrometers in length. (kenyon.edu)
  • Bordetella pertussis is an aerobic, gram-negative bacterium that causes symptoms by producing multiple antigenic and biologically active components, including pertussis toxin, filamentous hemagglutinin, and agglutinogens. (thefreelibrary.com)
  • B. pertussis , and occasionally B. parapertussis , can cause whooping cough in human infants. (sanger.ac.uk)
  • X68368 B.parapertussis gene for 23S ribosomal RNA. (atcc.org)
  • The presence of the Bordetella gene fragment is then detected by hybridization to a Bordetella-specific probe. (edu.au)
  • The Bordetella master virulence regulatory system, BvgAS, controls a spectrum of gene expression states, including the virulent Bvg + phase, the avirulent Bvg − phase, and at least one Bvg-intermediate (Bvg i ) phase. (asm.org)
  • These findings suggest B. parapertussis evolved in a host population that had already developed immunity to B. pertussis, where being able to evade B. pertussis immunity was an advantage. (wikipedia.org)
  • This led us to hypothesize that inefficient TLR4 stimulation enables B. parapertussis to evade host immunity. (elsevier.com)
  • Together, these results indicate that inefficient TLR4 stimulation by B. parapertussis enables it to avoid host immunity and grow to high numbers in the respiratory tract of naïve and immunized hosts. (elsevier.com)
  • Further, we show that aP vaccination impedes host immunity against B. parapertussis- measured as reduced lung inflammatory and neutrophil responses. (crazzfiles.com)
  • We evaluated the diagnostic performance of a genomic DNA amplification method for Bordetella pertussis and Bordetella parapertussis compared with culture isolation. (unife.it)
  • Since the efficacy of culture isolation, regarded as the standard for the detection of B. pertussis and B. parapertussis, declines after the first stage of pertussis or with prior vaccination or antibiotic therapy, PCR, although not yet standardized, may provide an alternative diagnostic tool. (unife.it)
  • This assay (LC-PCR-IS) targets the insertion sequences IS481 and IS1001 of B. pertussis and B. parapertussis, respectively, and is performed using the LightCycler (Roche Molecular Biochemicals, Indianapolis, Ind. (elsevier.com)
  • Pertussis (whooping cough) is an acute illness, caused by the Bordetella pertussis bacterium, involving the respiratory tract. (health.gov.au)
  • Lipsitch 1997 ), we hypothesize that the prolonged and widespread use of B. pertussis- specific aP vaccines has the potential to increase carriage of species not included in the vaccine, namely B. parapertussis . (crazzfiles.com)
  • The widely used acellular whooping cough vaccines (aP) are comprised solely of B. pertussis antigens that hold little or no efficacy against B. parapertussis . (crazzfiles.com)
  • Here, we postulate that the widespread and long-term use of acellular subunit pertussis vaccines creates hosts that are more favourable for B. parapertussis . (crazzfiles.com)
  • Expression of nearly all known Bordetella virulence and colonization factors is controlled by the BvgAS signal transduction system (reviewed in reference 8 ). (asm.org)
  • B. pertussis , which causes whooping cough in children and coughing illness in adolescents and adults ( 63 ), and B. parapertussis , which confers similar but milder clinical symptoms ( 22 ). (asm.org)
  • Bordetella parapertussis causes a similar, but generally less severe illness. (mayocliniclabs.com)
  • The aim of this study was to estimate the incidence of private practitioner-attended cough illness that could be attributed to Bordetella pertussis in adults aged ≥50 years in the US. (biomedcentral.com)

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