Bordetella
Bordetella bronchiseptica
Bordetella parapertussis
Bordetella pertussis
Virulence Factors, Bordetella
A set of BACTERIAL ADHESINS and TOXINS, BIOLOGICAL produced by BORDETELLA organisms that determine the pathogenesis of BORDETELLA INFECTIONS, such as WHOOPING COUGH. They include filamentous hemagglutinin; FIMBRIAE PROTEINS; pertactin; PERTUSSIS TOXIN; ADENYLATE CYCLASE TOXIN; dermonecrotic toxin; tracheal cytotoxin; Bordetella LIPOPOLYSACCHARIDES; and tracheal colonization factor.
Bordetella avium
Pertussis Vaccine
A suspension of killed Bordetella pertussis organisms, used for immunization against pertussis (WHOOPING COUGH). It is generally used in a mixture with diphtheria and tetanus toxoids (DTP). There is an acellular pertussis vaccine prepared from the purified antigenic components of Bordetella pertussis, which causes fewer adverse reactions than whole-cell vaccine and, like the whole-cell vaccine, is generally used in a mixture with diphtheria and tetanus toxoids. (From Dorland, 28th ed)
Hemagglutinins
Adenylate Cyclase Toxin
Pertussis Toxin
Probing the function of Bordetella bronchiseptica adenylate cyclase toxin by manipulating host immunity. (1/236)
We have examined the role of adenylate cyclase-hemolysin (CyaA) by constructing an in-frame deletion in the Bordetella bronchiseptica cyaA structural gene and comparing wild-type and cyaA deletion strains in natural host infection models. Both the wild-type strain RB50 and its adenylate cyclase toxin deletion (DeltacyaA) derivative efficiently establish persistent infections in rabbits, rats, and mice following low-dose inoculation. In contrast, an inoculation protocol that seeds the lower respiratory tract revealed significant differences in bacterial numbers and in polymorphonuclear neutrophil recruitment in the lungs from days 5 to 12 postinoculation. We next explored the effects of disarming specific aspects of the immune system on the relative phenotypes of wild-type and DeltacyaA bacteria. SCID, SCID-beige, or RAG-1(-/-) mice succumbed to lethal systemic infection following high- or low-dose intranasal inoculation with the wild-type strain but not the DeltacyaA mutant. Mice rendered neutropenic by treatment with cyclophosphamide or by knockout mutation in the granulocyte colony-stimulating factor locus were highly susceptible to lethal infection by either wild-type or DeltacyaA strains. These results reveal the significant role played by neutrophils early in B. bronchiseptica infection and by acquired immunity at later time points and suggest that phagocytic cells are a primary in vivo target of the Bordetella adenylate cyclase toxin. (+info)Evidence of efficacy of the Lederle/Takeda acellular pertussis component diphtheria and tetanus toxoids and pertussis vaccine but not the Lederle whole-cell component diphtheria and tetanus toxoids and pertussis vaccine against Bordetella parapertussis infection. (2/236)
A subanalysis of a recent cohort efficacy trial of a pertussis vaccine was performed to determine its efficacy against cough illnesses due to Bordetella parapertussis infections. Infants received four doses of either the Lederle/Takeda acellular pertussis component diphtheria and tetanus toxoids and pertussis (DTaP) vaccine or the Lederle whole-cell component diphtheria and tetanus toxoids and pertussis (DTP) vaccine at 3, 4.5, 6, and 15-18 months of age; controls received three doses of diphtheria and tetanus toxoids (DT) vaccine only. All subjects were prospectively followed for cough illnesses of > or = 7 days' duration; cases of B. parapertussis infection were confirmed by positive culture, household contact, or serology. Seventy-six cough illnesses due to B. parapertussis were identified; 24 occurred in 929 DTaP recipients, 37 in 937 DTP recipients, and 15 in 321 DT recipients, resulting in an efficacy of 50% for DTaP vaccine (95% CI [confidence interval], 5% to 74%) and 21% for DTP vaccine (95% CI, -45% to 56%). The data in the present analysis suggest that the Lederle/Takeda DTaP vaccine but not the Lederle whole-cell component DTP vaccine has efficacy against B. parapertussis infection. (+info)Outcomes of Bordetella infections in vaccinated children: effects of bacterial number in the nasopharynx and patient age. (3/236)
Five outbreaks of infection (three pertussis, one parapertussis, and one mixed) in schools were studied prospectively. Nasopharyngeal swabs were obtained from a total of 697 children for culture of Bordetella organisms. Of 50 vaccinated children with culture-confirmed Bordetella infections (29 with pertussis and 21 parapertussis), 40 were symptomatic and 10 remained symptom-free. Smaller numbers of colonies were recovered from the nasopharyngeal swabs of the asymptomatic children than from those of the symptomatic children. Older children had longer durations of illness than younger ones. Our results indicate that during outbreaks children who do not develop disease may have small amounts of Bordetella organisms in their nasopharynges and/or better immune defenses against the disease. (+info)Bordetella bronchiseptica infection in human immunodeficiency virus-infected patients. (4/236)
Bordetella bronchiseptica is a pleomorphic gram-negative coccobacillus that commonly causes respiratory tract infections in dogs. We identified nine human immunodeficiency virus (HIV)-infected persons with culture-confirmed B. bronchiseptica infections (eight respiratory tract and one disseminated infection). The respiratory illnesses ranged in severity from mild upper respiratory tract infection to pneumonia. All nine patients had had at least one AIDS-defining condition before the B. bronchiseptica infection. Two patients had household contact with dogs before their illnesses, and one had household contact with cats. Infection due to B. bronchiseptica is uncommon in HIV-infected persons. Additional data are needed to fully define the spectrum of disease due to B. bronchiseptica infections and to evaluate the possibility that this infection may be acquired from pets. Treatment of B. bronchiseptica infection should be tailored to the patient and should be based on the results of susceptibility testing. (+info)Parapertussis and pertussis: differences and similarities in incidence, clinical course, and antibody responses. (5/236)
OBJECTIVES: To compare the incidence, clinical course, and serologic response to Bordetella antigens in patients with parapertussis and pertussis. DESIGN: Two studies were performed in Sweden during the 1990s, when pertussis vaccines were used only in clinical trials. Study I was a retrospective study of patients with positive Bordetella cultures obtained in clinical routine, and study II involved an active search for patients with Bordetella infections during a placebo-controlled trial of a pertussis toxoid vaccine. RESULTS: Study I includes 58, and study II 23 patients with parapertussis. In study I, the incidence of parapertussis was 0.016 cases per 100 person years in children 0 to 6 years old and 0 in older children and adults. In study II, the incidence rates of parapertussis and pertussis were 0.2 and 16.2 per 100 person years, respectively, in children followed from 3 months to 3 years of age. The median number of days with cough was 21 in parapertussis and 59 in pertussis. The proportions of children with whooping and vomiting were lower in parapertussis than in pertussis. Geometric mean serum filamentous hemagglutinin IgG increased from 6 to 63, and pertactin IgG from 4 to 12 units/mL in parapertussis patients, which was similar to increases in children with pertussis. CONCLUSIONS: Disease caused by Bordetella parapertussis is diagnosed less commonly and is milder and of shorter duration than disease caused by Bordetella pertussis. Parapertussis induced serum IgG against filamentous hemagglutinin and pertactin of similar magnitude as does pertussis, and did not induce serum IgG against pertussis toxin. (+info)Pregenomic comparative analysis between bordetella bronchiseptica RB50 and Bordetella pertussis tohama I in murine models of respiratory tract infection. (6/236)
We describe here a side-by-side comparison of murine respiratory infection by Bordetella pertussis and Bordetella bronchiseptica strains whose genomes are currently being sequenced (Tohama I and RB50, respectively). B. pertussis and B. bronchiseptica are most appropriately classified as subspecies. Their high degree of genotypic and phenotypic relatedness facilitates comparative studies of pathogenesis. RB50 and Tohama I differ in their abilities to grow in the nose, trachea, and lungs of BALB/c mice and to induce apoptosis, lung pathology, and an antibody response. To focus on the interactions between the bacteria and particular aspects of the host immune response, we used mice with specific immune defects. Mice lacking B cells and T cells were highly susceptible to B. bronchiseptica and were killed by intranasal inoculation with doses as low as 500 CFU. These mice were not killed by B. pertussis, even when doses as high as 10(5) CFU were delivered to the lungs. B. bronchiseptica, which was highly resistant to naive serum in vitro, caused bacteremia in these immunodeficient mice, while B. pertussis, which was highly sensitive to naive serum, did not cause bacteremia. B. bronchiseptica was, however, killed by immune serum in vitro, and adoptive transfer of anti-Bordetella antibodies protected SCID-beige mice from B. bronchiseptica lethal infection. Neutropenic mice were similarly killed by B. bronchiseptica but not B. pertussis infection, suggesting neutrophils are critical to the early inflammatory response to the former but not the latter. B. bronchiseptica was dramatically more active than B. pertussis in mediating the lysis of J774 cells in vitro and in inducing apoptosis of inflammatory cells in mouse lungs. This side-by-side comparison describes phenotypic differences that may be correlated with genetic differences in the comparative analysis of the genomes of these two highly related organisms. (+info)Polymorphism in the pertussis toxin promoter region affecting the DNA-based diagnosis of Bordetella infection. (7/236)
The pertussis toxin (PT) promoter region is a frequently used target for DNA-based diagnosis of pertussis and parapertussis infections. The reported polymorphism in this region has also allowed discrimination of species in mixtures with several Bordetella species by their specific PCR amplicon restriction patterns. In the present study, we investigated the degree of polymorphism in order to confirm the reliability of the assay. Five different sequence types of the amplified 239- or 249-bp region were found among the 33 Bordetella pertussis, B. parapertussis, and B. bronchiseptica American Type Culture Collection reference strains and patient isolates analyzed. According to the sequences that were obtained and according to the PT promoter sequences already available in the databases, restriction enzyme analysis with TaqI, BglI, and HaeII, which gave four different patterns, can be performed to reliably identify B. pertussis, B. parapertussis, and B. bronchiseptica. (+info)Biological activities of lipopolysaccharides extracted from porcine vaccine strains. (8/236)
Lipopolysaccharides (LPSs) were purified from Actinobacillus pleuropneumoniae serotype 2, Bordetella bronchiseptica and Haemophilus parasuis serotype 5, which were used for vaccine production in Japan, by the phenol-water procedure. In SDS-PAGE analysis, A. pleuropneumoniae LPS, as well as Escherichia coli LPS, demonstrated a typical ladder profile of a smooth-type LPS. On the other hand, B. bronchiseptica and H. parasuis LPSs lacked the ladder profiles. It was found that the biological activity of these LPSs was comparable to those of E. coli LPS in terms of activation of the clotting enzyme of Limulus amoebocyte lysate, mitogenic activity of mouse spleen cells, stimulation of TNF-alpha and nitric oxide production, but IL-6 production could hardly be observed in any LPS. (+info) Bordetella Infections are bacterial infections caused by the Bordetella pertussis or Bordetella parapertussis bacteria. These bacteria are responsible for causing the respiratory disease known as Whooping Cough. The infection is primarily spread through contact with an infected person's respiratory secretions, such as mucus and saliva.
Symptoms of Bordetella Infections typically include a severe cough, fever, and difficulty breathing. In severe cases, the infection can lead to pneumonia or other complications that may require hospitalization.
Diagnosis of Bordetella Infections is usually made through laboratory tests, such as a PCR (polymerase chain reaction) test or a culture. Treatment typically involves antibiotics, which can help reduce the severity and duration of symptoms. Prevention is key, as there is no specific treatment for Bordetella Infections once they have developed. Vaccination against Bordetella pertussis is recommended for children and adults to protect against infection.
Rhinitis, atrophic is a type of chronic inflammatory condition that affects the nasal passages and sinuses. It is characterized by the loss of the normal architecture of the nasal mucosa, including the epithelium, submucosa, and glands. The condition is often associated with allergies, and symptoms can include nasal congestion, rhinorrhea, and loss of sense of smell.
The term "atrophic" refers to the wasting away or degeneration of tissue, which is a hallmark feature of this condition. The atrophy of the nasal mucosa can lead to a decrease in the production of mucus, which can impair the body's ability to fight off infections and allergens.
Rhinitis, atrophic can be caused by a variety of factors, including allergies, viral infections, and exposure to environmental irritants such as smoke or pollution. The condition is more common in older adults and can be associated with other medical conditions such as asthma, sinusitis, and chronic bronchitis.
There are several risk factors for developing rhinitis, atrophic, including:
1. Allergies: People with allergies are more likely to develop rhinitis, atrophic.
2. Age: The condition is more common in older adults.
3. Family history: A family history of allergies or respiratory conditions can increase the risk of developing rhinitis, atrophic.
4. Exposure to environmental irritants: Smoke, pollution, and other environmental irritants can increase the risk of developing the condition.
5. Previous respiratory infections: People who have had previous respiratory infections, such as the common cold or flu, may be more likely to develop rhinitis, atrophic.
There are several symptoms of rhinitis, atrophic, including:
1. Nasal congestion: The nasal passages can become inflamed and congested, making it difficult to breathe through the nose.
2. Rhinorrhea: Thick, yellowish discharge from the nose is a common symptom of rhinitis, atrophic.
3. Postnasal drip: This can cause a sore throat and coughing.
4. Loss of smell: The inflammation in the nasal passages can damage the olfactory nerve, leading to a loss of sense of smell.
5. Sinus pressure: The condition can lead to sinus pressure and pain.
There are several complications of rhinitis, atrophic, including:
1. Chronic sinusitis: The condition can lead to chronic sinusitis, which can cause pain, facial swelling, and difficulty breathing through the nose.
2. Asthma: Some people with rhinitis, atrophic may develop asthma.
3. Middle ear infections: The infection in the nasal passages can spread to the middle ear, leading to ear infections.
4. Meningitis: In rare cases, the infection can spread to the meninges, leading to meningitis.
There are several treatments for rhinitis, atrophic, including:
1. Nasal decongestants: These medications can help reduce swelling in the nasal passages and relieve congestion.
2. Antihistamines: These medications can help reduce nasal discharge and relieve itching.
3. Corticosteroids: These medications can help reduce inflammation in the nasal passages.
4. Antibiotics: If there is a bacterial infection, antibiotics may be prescribed.
5. Saline nasal sprays: These can help moisturize the nasal passages and thin mucus.
6. Humidifiers: Using a humidifier can help keep the nasal passages moist and relieve congestion.
7. Nasal strips: These can help open up the nasal passages and improve breathing.
8. Surgery: In severe cases, surgery may be necessary to remove polyps or correct anatomical abnormalities.
It is important to note that these treatments may not completely cure the condition, but they can help manage the symptoms and prevent complications. It is also important to work with a healthcare professional to determine the best course of treatment for your specific case.
List Biological Laboratories
"Vaccine Development for the Control of Bordetella Pertussis Infections". Infection and Immunity. 86 (6): e00004-18. doi:10.1128 ...
Bordetella pertussis
Carbonetti, Nicholas H (2007-06-01). "Immunomodulation in the pathogenesis of Bordetella pertussis infection and disease". ... 2003). "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella ... Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus of the genus Bordetella, and the ... Nieves DJ, Heininger U (2016). "Bordetella pertussis". Bordetella pertussis. Microbiology Spectrum. Vol. 4. pp. 311-339. doi: ...
Kennel cough
"Detection of Respiratory Viruses and Bordetella Bronchiseptica in Dogs with Acute Respiratory Tract Infections". The Veterinary ... mixed or secondary infections can progress to lower respiratory infections such as pneumonia. The incubation period is 5-7 days ... Viral infections such as canine parainfluenza or canine coronavirus are only spread for roughly one week following recovery; ... Kennel cough is so named because the infection can spread quickly among dogs in the close quarters of a kennel or animal ...
Harold Lambert (physician)
"Human Serum Antibody Responses to Bordetella pertussis Infection and Pertussis Vaccination". The Journal of Infectious Diseases ... with Arnold Eley and T. Hargreaves: Eley, A.; Hargreaves, T.; Lambert, H. P. (10 July 1965). "Jaundice in Severe Infections". ... Lambert's main research interests were meningitis, respiratory infections, and the optimal use of antibiotics. After retiring ... Journal of Infection. 46 (2): 75-77. doi:10.1053/jinf.2002.1110. PMID 12634067. "A tribute to Professor Harold Lambert". ...
Bordetella holmesii
It is often seen in conjunction with Bordetella pertussis infections (whooping cough), although not always. Weyant, Robbin S.; ... Bordetella holmesii is a Gram-negative, rod-shaped bacterium of the genus Bordetella. It was named in recognition of Barry ... August 2006). "Bordetella holmesii DNA is not detected in nasopharyngeal swabs from Finnish and Dutch patients with suspected ... 1995). "Bordetella holmesii sp. nov., a new Gram-negative species associated with septicemia". Journal of Clinical Microbiology ...
Bordetella
... and Clinical Manifestations of Respiratory Infections Due to Bordetella pertussis and Other Bordetella Subspecies". Clin ... After 42 days, the dogs were exposed to Bordetella bronchiseptica. This study determined that the live intranasal Bordetella ... The Bordetella vaccine is also only about 70% effective (Bryant). There are 3 licensed ways to deliver the Bordetella vaccine ... The Bordetella vaccine specifically targets Bordetella bronchiseptica, the species typically responsible for kennel cough. The ...
Tracheal cytotoxin
1991). "Effects of Bordetella pertussis infection on human respiratory epithelium in vivo and in vitro". Infection and Immunity ... 1991-01-01). "Effects of Bordetella pertussis infection on human respiratory epithelium in vivo and in vitro". Infection and ... 2003). "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella ... and Clinical Manifestations of Respiratory Infections Due to Bordetella pertussis and Other Bordetella Subspecies". Clinical ...
Bordetella parapertussis
"The O Antigen Enables Bordetella parapertussis To Avoid Bordetella pertussis-Induced Immunity". Infection and Immunity. 75 (10 ... Bordetella parapertussis is a small Gram-negative bacterium of the genus Bordetella that is adapted to colonise the mammalian ... "Predisposition of specific pathogen-free lambs to Pasteurella haemolytica pneumonia by Bordetella parapertussis infection". J ... "Clinical characteristics of illness caused by Bordetella parapertussis compared with illness caused by Bordetella pertussis". ...
Adenylate cyclase toxin
The effect on neutrophils is most important in early infection with Bordetella, impairing most of their antimicrobial functions ... Bordetella pertussis. Bordetella bronchiseptica and Bordetella parapertussis, also able to cause pertussis-like symptoms, also ... Vaccination against Bordetella pertussis is used in infancy to prevent whooping cough. The recent switch from whole-cell ... Although phagocytic immune cells migrate to the site of infection in the lungs, they are not able to mount an effective ...
Bordetella avium
As the severity of disease increases the most common comorbidity associated with Bordetella avium is a secondary infection with ... Bordetella avium is a gram negative, nonfermentative, strictly aerobic, motile bacterium from the genus Bordetella which has ... "Prevalence of Bordetella avium Infection in Selected Wild and Domesticated Birds in the Eastern USA". Journal of Wildlife ... Isolation of Bordetella avium and Novel Bordetella Strain from Patients with Respiratory Disease. Emerg Infect Dis. 2009 Jan; ...
Guinea pig
Rabbits may also harbor diseases (such as respiratory infections from Bordetella and Pasteurella), to which guinea pigs are ... abscesses due to infection (often in the neck, due to hay embedded in the throat, or from external scratches), and infections ... Housing guinea pigs with other rodents such as gerbils and hamsters may increase instances of respiratory and other infections ... Common ailments in domestic guinea pigs include respiratory tract infections, diarrhea, scurvy (vitamin C deficiency, typically ...
Bordetella bronchiseptica
J Clin Microbiol 31(7): 1838-44 "Prevention and control of Bordetella bronchiseptica infection in cats". Intervet/Schering- ... Bordetella bronchiseptica is a small, gram-negative, rod-shaped bacterium of the genus Bordetella. It can cause infectious ... Genetic sequences of the Bordetella bronchiseptica complex (Sanger Institute) Type strain of Bordetella bronchiseptica at ... Hewlett, EL (1995). "Bordetella species." In: Principles and Practice of Infectious Diseases (Mandel, GL, Bennett, JE, Dolin, R ...
Pertussis toxin
"Selection and emergence of pertussis toxin promoter ptxP3 allele in the evolution of Bordetella pertussis". Infection, Genetics ... Bordetella parapertussis shows the most similarity to B. pertussis and was therefore used for research determining the role of ... PT is involved in the colonization of the respiratory tract and the establishment of infection. Research suggests PT may have a ... One difference between the different species of Bordetella is that B. pertussis produces PT and the other species do not. ...
Bronchitis
A small number of cases are caused by a bacterial infection such as Mycoplasma pneumoniae or Bordetella pertussis. Risk factors ... Bronchitis usually begins as an infection in the nose, ears, throat, or sinuses. The infection then makes its way down to the ... Acute bronchitis is normally caused by a viral infection. Typically, these infections are rhinovirus, parainfluenza, or ... The infection may last from a few to ten days. The cough may persist for several weeks afterwards, with the total duration of ...
Macrolide
Bordetella pertussis, Haemophilus influenzae), and some respiratory tract and soft-tissue infections. The antimicrobial ... This is evident, as the treatment dosage is much too low to fight infection, and in DPB cases with the occurrence of the ... Macrolides are actively concentrated within leukocytes, and thus are transported into the site of infection. The macrolide ... They are used to treat respiratory tract infections caused by macrolide-resistant bacteria. Ketolides are especially effective ...
Exotoxin
DPT vaccine protects against pertussis, tetanus and diphtheria infections, caused by the exotoxin-producing Bordetella ... However, induction of cell lysis may not be the primary function of the toxins during infection. At low concentrations of toxin ... These "toxins" allow the further spread of bacteria and, as a consequence, deeper tissue infections. Examples are hyaluronidase ... Tweten RK (October 2005). "Cholesterol-dependent cytolysins, a family of versatile pore-forming toxins". Infection and Immunity ...
CyaA
As a result, it enables establishment of Bordetella infection of airway mucosa and promotes immune evasion of B. pertussis, by ... preventing the induction of adaptive immune responses to Bordetella infections. The enzymatic AC activity of CyaA also seems to ... Adenylate cyclase toxin (CyaA) is released from bacterium Bordetella pertussis by the T1SS (Type 1 secretion system) and ... September 2017). "Structure-Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host ...
Vaccine resistance
"Pertactin negative Bordetella pertussis demonstrates higher fitness under vaccine selection pressure in a mixed infection model ... Since the immunity conferred by a vaccine may be different from that induced by infection by the pathogen, the immune evasion ... If vaccine resistance emerges the vaccine may retain some level of protection against serious infection, possibly by modifying ... Hegerle, Nicolas; Guiso, Nicole (2014-09-01). "Bordetella pertussis and pertactin-deficient clinical isolates: lessons for ...
List of MeSH codes (C01)
... bordetella infections MeSH C01.252.400.143.740 - whooping cough MeSH C01.252.400.155 - borrelia infections MeSH C01.252.400.155 ... bacteroides infections MeSH C01.252.400.126 - bartonellaceae infections MeSH C01.252.400.126.100 - bartonella infections MeSH ... moraxellaceae infections MeSH C01.252.400.560.022 - acinetobacter infections MeSH C01.252.400.610 - mycoplasmatales infections ... salmonella infections, animal MeSH C01.252.400.310.821.873 - typhoid fever MeSH C01.252.400.310.850 - serratia infections MeSH ...
Hyperinsulinemic hypoglycemia
Drug induced hyperinsulinism Sulfonylurea Aspirin Pentamidine Quinine Disopyramide Bordetella pertussis vaccine or infection D- ...
Alpha-D-phosphohexomutase superfamily
"Avirulence of a Pseudomonas aeruginosa algC mutant in a burned-mouse model of infection". Infection and Immunity. 63 (10): 4166 ... West NP, Jungnitz H, Fitter JT, McArthur JD, Guzmán CA, Walker MJ (August 2000). "Role of phosphoglucomutase of Bordetella ... Pei J, Ficht TA (January 2004). "Brucella abortus rough mutants are cytopathic for macrophages in culture". Infection and ... Infection and Immunity. 64 (1): 37-43. doi:10.1128/iai.64.1.37-43.1996. PMC 173724. PMID 8557368. Tavares IM, Leitão JH, Sá- ...
Adenylyl cyclase
Guo Q, Shen Y, Lee YS, Gibbs CS, Mrksich M, Tang WJ (September 2005). "Structural basis for the interaction of Bordetella ... and Vibrio vulnificus during infections. These bacteria also secrete proteins that enable the AC-II to enter host cells, where ... These adenylyl cyclases are toxins secreted by pathogenic bacteria such as Bacillus anthracis, Bordetella pertussis, ...
List of feline diseases
... an upper respiratory tract infection, caused by: Bordetella bronchiseptica Chlamydophila felis Feline calicivirus Feline viral ... Feline disease are those infections or diseases that infect cats. Some of these cause symptoms, sickness or the death of the ... fever caused by Rickettsia felis Florida keratopathy Haemophilus felis Head pressing Heart valve dysplasia Hookworm infection ...
Peptidoglycan recognition protein 4
... associated with impaired bacterial clearance and more severe pulmonary inflammation following Bordetella pertussis infection, ... Intranasal administration of PGLYRP4 protects mice from lung infection with S. aureus and E. coli and PGLYRP4-deficient mice ... Skerry C, Goldman WE, Carbonetti NH (February 2019). "Bordetella pertussis and Contributes to Sphingosine-1-Phosphate Receptor ... PGLYRP4 plays a limited role in host defense against infections. ... Agonist-Mediated Disease Attenuation". Infection and Immunity. ...
Pertactin
"Pertactin is required for Bordetella species to resist neutrophil-mediated clearance". Infection and Immunity. 78 (7): 2901-9. ... PRN is purified from Bordetella pertussis and is used for the vaccine production as one of the important components of ... Emsley, P.; Charles, I. G.; Fairweather, N. F.; Isaacs, N. W. (1996). "Structure of Bordetella pertussis virulence factor P.69 ... Emsley P, Charles IG, Fairweather NF, Isaacs NW (May 1996). "Structure of Bordetella pertussis virulence factor P.69 pertactin ...
DA2PPC vaccine
... but the combination of Bordetella with DA2PPC significantly reduces kennel cough infection through prevention of adenovirus, ... Treatment is supportive and consists of antibiotics to prevent secondary infections, anticonvulsants for seizures, and ... is a DNA viral upper respiratory infection contracted through contact of a mucous membrane. Symptoms include: vomiting, ... DA2PPC does not include vaccination against Bordetella, ...
Bordetella trematum
It has been isolated from human ear infection and limb wounds. Below is a list of known B. trematum strains, alternative strain ... Bordetella endotoxins are unique to the genus, species, and strain. B. trematum is the only Bordetella species with a semirough ... It is unique in being oxidase negative, since all other species of Bordetella are oxidase positive. Bordetella trematum may be ... Bordetella species typically infect the respiratory tracts of humans, but B. trematum has never been isolated from a human or ...
Upper respiratory tract infection
... and Bordetella pertussis may prevent them from infecting the URT or reduce the severity of the infection.[citation needed] ... "Infections of the Respiratory System". Chapter 93: Infections of the Respiratory System. National Center for Biotechnology ... An upper respiratory tract infection (URTI) is an illness caused by an acute infection, which involves the upper respiratory ... Guibas GV, Papadopoulos NG (2017). "Viral Upper Respiratory Tract Infections". In Green RJ (ed.). Viral Infections in Children ...
Hedgehog
This ringworm or dermatophytosis infection is caused by Trichophyton erinacei, which forms a distinct mating group within the ... This is known to be caused by the Bordetella bronchiseptica bacterium. Hedgehogs uncommonly transmit a characteristic fungal ... a rare condition in which gas is trapped under the skin as a result of injury or infection and which causes the animal to ... believe anointing camouflages the hedgehog with the new scent of the area and provides a possible poison or source of infection ...
Peptidoglycan recognition protein
Some of these amidases are also directly bactericidal, which further defends the host against infections and helps to control ... "Peptidoglycan Recognition Protein 4 Suppresses Early Inflammatory Responses to Bordetella pertussis and Contributes to ... They likely defend the hosts against infections or regulate colonization by certain commensal bacteria, such as Vibrio fischeri ... Intranasal application of PGLYRP3 or PGLYRP4 in mice protects from intranasal lung infection with Staphylococcus aureus and ...
Pattern recognition receptor
Since all types of PRRs play a role in the identification and eradication of the infection, their specific agonists mount a ... "Mannose receptor and macrophage galactose-type lectin are involved in Bordetella pertussis mast cell interaction". Journal of ... In a healthy individual Helicobacter pylori infection is targeted by the combination of PRRs, namely TLRs, NLRs, RLRs and CLR ... Burberry A, Zeng MY, Ding L, Wicks I, Inohara N, Morrison SJ, Núñez G (June 2014). "Infection mobilizes hematopoietic stem ...
Childhood immunizations in the United States
It can also help prevent ear infections. Previous infection from the disease does not grant immunity from future infection ... Pertussis is a highly contagious disease that is caused by the bacteria Bordetella pertussis. The bacteria clings to cilia in ... People who are in close contact with someone who has the disease are at increased risk of infection. In the case of infection, ... It prevents meningitis, Hib pneumonia, Hib epiglottitis (severe throat infection) and other infections that are a result of ...
Whooping cough
Infection induces incomplete natural immunity that wanes over time. A 2005 study said estimates of the duration of infection- ... Pertussis is caused by the bacterium Bordetella pertussis. It is spread easily through the coughs and sneezes of an infected ... The time between infection and the onset of symptoms is usually seven to ten days. Disease may occur in those who have been ... Pertussis infection in these persons may be asymptomatic, or present as illness ranging from a mild cough to classic pertussis ...
Duncan Maskell
"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica". ... Salmonella infections: clinical, immunological, and molecular aspects. Cambridge: Cambridge University Press. García-Álvarez, ... Infection and Immunity. 56 (2): 419-423. doi:10.1128/IAI.56.2.419-423.1988. ISSN 0019-9567. PMC 259298. PMID 3276625. Reeves, ... He completed a PhD in the Department of Pathology in 1986 on Salmonella infections. At 11, he performed at the Queen Elizabeth ...
Toxoid
OCLC 630453151.{{cite book}}: CS1 maint: others (link) "Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde ... Infection and Immunity. 65 (6): 2088-93. doi:10.1128/IAI.65.6.2088-2093.1997. PMC 175288. PMID 9169736. v t e (CS1 maint: ... Infection and Immunity. 13 (6): 1692-8. doi:10.1128/iai.13.6.1692-1698.1976. PMC 420821. PMID 823107. "NIBSC - Anthrax". www. ...
Azurin
... is a small, periplasmic, bacterial blue copper protein found in Pseudomonas, Bordetella, or Alcaligenes bacteria. Azurin ... Infection and Immunity. 70 (12): 7054-62. doi:10.1128/IAI.70.12.7054-7062.2002. PMC 133031. PMID 12438386. van den Bosch M, ...
Clarithromycin
It is effective against upper and lower respiratory tract infections, skin and soft tissue infections and helicobacter pylori ... Viridans group streptococci Aerobic Gram-negative bacteria Bordetella pertussis Legionella pneumophila Pasteurella multocida ... This includes strep throat, pneumonia, skin infections, H. pylori infection, and Lyme disease, among others. Clarithromycin can ... Other uses include cat scratch disease and other infections due to bartonella, cryptosporidiosis, as a second line agent in ...
Polymerase chain reaction
However, antibodies don't appear until many weeks after infection, maternal antibodies mask the infection of a newborn, and ... Diseases such as pertussis (or whooping cough) are caused by the bacteria Bordetella pertussis. This bacteria is marked by a ... Infections can be detected earlier, donated blood can be screened directly for the virus, newborns can be immediately tested ... The high sensitivity of PCR permits virus detection soon after infection and even before the onset of disease. Such early ...
Immunologic adjuvant
... they may induce the release of inflammatory cytokines which helps to not only recruit B and T cells at sites of infection but ... killed bacteria of the species Bordetella pertussis, Mycobacterium bovis,[citation needed] toxoids Plant saponins from Quillaja ... either in the form of adjuvant used in vaccinations or in the form of invasive moieties during times of natural infection - TLR ... mast cells release heparin and histamine to effectively increase trafficking to and seal off the site of infection to allow ...
Vaccination of dogs
... local environment or lifestyle places them at risk of contracting specific infections. Except in areas where the disease is ... vets may recommend administering a vaccine against the bacteria Bordetella, which causes respiratory illness commonly known as ...
Immunization during pregnancy
In childhood, it usually causes a mild disease but infection in pregnancy can result in fetal infection, or congenital rubella ... Whooping cough, or pertussis, is a contagious respiratory disease caused by the bacteria Bordetella pertussis. It is fatal in ... Infection significantly increased the risk of preterm birth, stillbirth and pre-eclampsia. mRNA COVID-19 vaccines were first ... COVID-19 is a respiratory infection caused by the SARS-CoV2 virus. Before COVID-19 vaccines were available, pregnant women who ...
Subclinical infection
Baylisascaris procyonis Bordetella pertussis (Pertussis or whooping cough) Chlamydia pneumoniae Chlamydia trachomatis ( ... A subclinical infection-sometimes called a preinfection or inapparent infection-is an infection that, being subclinical, is ... Such infections occur both in humans and animals. An example of an asymptomatic infection is a mild common cold that is not ... Subclinical infections are important since they allow infections to spread from a reserve of carriers. They also can cause ...
Bacillus anthracis
Untreated B. anthracis infection is usually deadly. Infection is indicated by inflammatory, black, necrotic lesions (eschars). ... Like Bordetella pertussis, it forms a calmodulin-dependent adenylate cyclase exotoxin known as anthrax edema factor, along with ... Its infection is a type of zoonosis, as it is transmitted from animals to humans. It was discovered by a German physician ... Infections with B. anthracis can be treated with β-lactam antibiotics such as penicillin, and others which are active against ...
AB5 toxin
The bacterium Bordetella pertussis was first identified as the cause of whooping cough and isolated by Jules Bordet and Octave ... In addition to some of these AB5 toxins being used to create vaccines to prevent bacterial infection, they are also being ... Guiso N. 2009.Bordetella pertussis and pertussis vaccines. Clin. Infect. Dis. 49:1565-1569 "1.C.72 The Pertussis Toxin (PTX) ... Pertussis toxin is secreted by the gram-negative bacterium, Bordetella pertussis. Whooping cough is very contagious and cases ...
Risk assessment for organic swine health
Toxoplasma gondii infection in humans and animals in the United States. International Journal for Parasitology 38 (11): 1257-78 ... bordetella bronchiseptica, porcine parvovirus, and Erysipelothrix rhusiopathiae among others. It is particularly important to ... This is probably a result of the alternative system leading to a lower infection level, since no difference in mortality pigs ... Toxoplasma gondii Infection in Animal-Friendly Pig Production Systems. Investigative Ophthalmology and Visual Science. vol. 45 ...
Emerging infectious disease
"Emerging infections: how and why they arise". 27 February 2019. Gerrard, Sonja R.; Li, Li; Barrett, Alan D.; Nichol, Stuart T ... Anaplasmosis Aspergillus BK virus Bordetella pertussis Borrelia miyamotoi Clostridium difficile Cryptococcus gattii ... Emerging infections account for at least 12% of all human pathogens. EIDs can be caused by newly identified microbes, including ... Nosocomial (hospital-acquired) infections, such as methicillin-resistant Staphylococcus aureus are emerging in hospitals, and ...
Vaccine-preventable diseases
31 vaccine-preventable infections. In 2012, the World Health Organization estimated that vaccination prevents 2.5 million ... Bordetella Canine distemper Canine influenza Canine parvovirus Chlamydia Feline calicivirus Feline distemper Feline leukemia ... which leaves them vulnerable to infection if travelling to areas where risk of yellow fever is highest (endemic or transitional ... Haemophilus influenzae serotype b infection, hepatitis B, measles, meningitis, mumps, pertussis, poliomyelitis, rubella, ...
Pharyngitis
Most cases are caused by a viral infection. Strep throat, a bacterial infection, is the cause in about 25% of children and 10% ... Bordetella pertussis, Bacillus anthracis, Corynebacterium diphtheriae, Neisseria gonorrhoeae, Chlamydophila pneumoniae, ... Antibiotics are useful if a bacterial infection is the cause of the sore throat. For viral infections, antibiotics have no ... submandibular space infection (Ludwig's angina), and epiglottitis. Some cases of pharyngitis are caused by fungal infection, ...
Filamentation
Lastly, bacteriophage infection can result in filamentation via the expression of proteins that inhibit divisome assembly. ... In addition, filamentation is induced by nutrient-rich conditions in the intracellular pathogen Bordetella atropi. This occurs ... Microbes and Infection. 12 (6): 488-96. doi:10.1016/j.micinf.2010.03.001. PMC 288367. PMID 20223293. Ragunathan, PT; Vanderpool ... CK (1 December 2019). "Cryptic-prophage-encoded small protein DicB protects Escherichia coli from phage infection by inhibiting ...
Lymphocyte
An increase in lymphocyte concentration is usually a sign of a viral infection (in some rare case, leukemias are found through ... Pertussis toxin (PTx) of Bordetella pertussis, formerly known as lymphocytosis-promoting factor, causes a decrease in the entry ... Lymphocytes are recruited into the upper and lower airways during the early stages of a viral respiratory infection, and it is ... A low normal to low absolute lymphocyte concentration is associated with increased rates of infection after surgery or trauma. ...
Helen Petousis-Harris
Because pertussis is known to be caused by the bacterium Bordetella pertussis, vaccination is effective. A paper co-authored in ... The study shows that vaccination helps to reduce middle ear infections and urges parents to monitor their children closely. ... "Maori and Pacific Island Children Afflicted with Ear Infections". 24 November 2015. Archived from the original on 6 March 2021 ... Petousis-Harris earlier said the study demonstrates that the vaccine Synflorix reduces pneumonia, middle ear infections and ...
Rhinitis
Sinus Infection And Allergic Rhinitis Specialist Library for ENT and Audiology Hay fever resources - online library of high ... and Bordetella pertussis may help prevent it. The management of rhinitis depends on the underlying cause. For allergic rhinitis ... Rhinitis is commonly caused by a viral or bacterial infection, including the common cold, which is caused by Rhinoviruses, ... Vasomotor rhinitis is differentiated from viral and bacterial infections by the lack of purulent exudate and crusting. It can ...
Uromodulin
The excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. The ... "Interaction of human Tamm-Horsfall glycoprotein with Bordetella pertussis toxin". Microbiology. 148 (Pt 4): 1193-1201. doi: ... "Architecture and function of human uromodulin filaments in urinary tract infections". Science. New York, N.Y. 369 (6506): 1005- ...
Opportunistic Pulmonary Bordetella hinzii Infection after Avian Exposure - Volume 21, Number 12-December 2015 - Emerging...
Bordetella petrii infection with long-lasting persistence in human. Emerg Infect Dis. 2011;17:612-8. DOIPubMedGoogle Scholar ... Opportunistic Pulmonary Bordetella hinzii Infection after Avian Exposure On This Page Clinical Cases Microbiological ... Respiratory infection caused by Bordetella hinzii. Arch Bronconeumol. 2013;49:409-10 .PubMedGoogle Scholar ... Bordetella hinzii bacteria cause respiratory infections in birds and have been isolated from rodents on rare occasions (1,2). ...
Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections | BMC Infectious Diseases ...
... pertussis infection alone and those with respiratory viral coinfections. We also analyzed how respiratory infections were ... Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We ... Monthly Distribution of the 53 Cases of Bordetella pertussis Infection Through the 2-Year Study ... From: Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections ...
Virus Coinfection is a Predictor of Radiologically Confirmed Pneumonia in Children with Bordetella pertussis Infection
بحث
Pertussis Clinical Presentation: History, Physical Examination
The most common causative organism is Bordetella pertussis (see the image below), though Bordetella parapertussis has also been ... is a respiratory tract infection characterized by a paroxysmal cough. ... and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies. Clin ... Characteristics of Severe Bordetella pertussis Infection Among Infants Older than 90 Days of Age Admitted to Pediatric ...
Advanced Search Results - Public Health Image Library(PHIL)
SSPT I
Elevated Pertussis Reporting in Response to 2011-2012 Outbreak, New York City, New York, USA - Volume 22, Number 6-June 2016 -...
Vaccination | American Board of Family Medicine
WHO EMRO | Patterns of meningococcal infection in Sudan with emergence of Neisseria meningitidis serogroup W135 | Volume 19,...
Infections caused by Haemophilus and Bordetella species. In: Kelley WN, ed. Textbook of Internal Medicine, 3rd ed. New York, ... Patterns of meningococcal infection in Sudan with emergence of Neisseria meningitidis serogroup W135 ... Infection, Genetics and Evolution, 2001, 1(2):117-122.. *Salih MA et al. Characterization of epidemic and nonepidemic Neisseria ... Tableau des infections à méningocoques au Soudan avec lémergence du sérogroupe W135 de Neisseria meningitidis ...
Search
There were some severe cases of pertussis among infants caused mainly by B. pertussis and dual Bordetella infection. Infection ... Bordetella spp. was isolated in 48.1% of the cases. The isolation rate was highest among infants and decreased with increasing ... B. pertussis was the most common species; however, B. parapertussis infection did occur. ...
KoreaMed
What Are The Real Causes of Sudden Infant Death Syndrome (SIDS)? Why Are Vaccines Excluded?
Infection and Immunity; 33. Biological activities of crystalline pertussigen from Bordetella pertussis. Infection and Immunity ... The effects of posture in infants with more severe lower respiratory tract infection and during active sleep has yet to be ... Groups of healthy infants (n=34), infants with upper respiratory tract infections (n=13) and infants with generalised ... Biological activities of crystalline pertussigen from Bordetella pertussis. ...
Pediatric Pneumonia: Practice Essentials, Background, Pathophysiology
Bordetella pertussis infection leads to pneumonia in as many as 20% of infected infants (as a complication of the whooping ... of all lower respiratory tract infections. Tsolia et al identified a viral infection among 65% of hospitalized children with ... or those with frequent ear infections are at increased risk for invasive pneumococcal disease and infection with resistant ... Bacterial infections in this age group are seen on a regular basis. S pneumoniae is by far the most common bacterial cause of ...
Pertussis: MedlinePlus Medical Encyclopedia
Pertussis, or whooping cough, is an upper respiratory infection. It is caused by the Bordetella pertussis bacteria. It is a ... Pertussis (Bordetella pertussis and Bordetella parapertussis). In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, ... The symptoms of infection often lasts 6 weeks, but it can last as long as 10 weeks. ... DTaP vaccination, one of the recommended childhood immunizations, protects children against pertussis infection. DTaP vaccine ...
Guideline for Infection Control in Hospital Personnel
Pertussis, caused by Bordetella pertussis, is highly communicable. The secondary attack rate is determined primarily by the ... Viral respiratory infections are common problems for infection control programs. The role of viruses in nosocomial infections ... CDC GUIDELINES ON INFECTION CONTROL. INTRODUCTION. OBJECTIVES OF A PERSONNEL HEALTH SERVICE FOR INFECTION CONTROL. ELEMENTS OF ... CDC GUIDELINES ON INFECTION CONTROL. The Guideline for Infection Control in Hospital Personnel is part of the Guidelines for ...
Pesquisa | Biblioteca Virtual em Saúde
Features of Bordetella pertussis, Bordetella spp. infection and whopping cough in Córdoba province, Argentina]. / ... y coqueluche en la provincia de Córdoba, Argentina / Features of Bordetella pertussis, Bordetella spp. infection and whopping ... Caracterización de la infección por Bordetella pertussis, Bordetella spp. ... Caracterización de la infección por Bordetella pertussis, Bordetella spp. y coqueluche en la provincia de Córdoba, Argentina. ...
Dogs and kennel cough - BeeDogs.com
... there is a viral infection with the canine parainfluenza virus followed by a secondary bacterial infection with Bordetella ... The cough can sound very serious; however, the infection usually clears up within one to two weeks. Vets should be able to ... One of the most common respiratory infections in dogs is Infectious tracheobronchitis, which is also known as kennel cough. ... According to vet professionals, this is a highly contagious infection caused by a combination of infectious agents. Many times ...
Marina Annetta Lynch : School of Biochemistry and Immunology - Trinity College Dublin
Lung CD4 tissue-resident memory T cells mediate adaptive immunity induced by previous infection of mice with bordetella ... Induction of inflammatory cytokines in the brain following respiratory infection with bordetella pertussis, Journal of ... McManus, R.M., Finucane, O.M., Wilk, M.M., Mills, K.H.G., Lynch, M.A. , FTY720 Attenuates Infection-Induced Enhancement of Aβ ... McManus R, Mills, KHG, Lynch MA, Respiratory infection promotes T cell infiltration and Aβ deposition in APP/PS1 mice., ...
Evidence of Host-Specific Subgroups among "Histophilus ovis" Isolates | Microbiology Society
Respiratory Therapeutics - WSAVA2008 - VIN
... specifically those due to Bordetella infections), but are not appropriate as the sole therapy for pneumonic cases. ... If the infection is thought to be tracheobronchial (intra-luminal) then there should be concern about antibiotic penetration ... Upper airway cultures (nasal cavity) are rarely helpful as infections there are secondary; tonsillar swabs are not indicative ... and especially the fluoroquinolones are good choices for lower airway infections. The route of administration is a concern for ...
DeCS
Infections with bacteria of the genus BORDETELLA. Preferred term. Bordetella Infections Entry term(s). Bordetella Infection ... Bordetella Infections - Preferred Concept UI. M0002821. Scope note. ... Bordetella Infection. Infection, Bordetella. Infections, Bordetella. Tree number(s):. C01.150.252.400.143. ... Bordetella Infections Descriptor Spanish: Infecciones por Bordetella Spanish from Spain Descriptor. infecciones por Bordetella ...
Azithromycin is as effective as and better tolerated than erythromycin estolate for the treatment of pertussis.
OBJECTIVE: Although universal immunization against Bordetella pertussis (whooping cough) infection has resulted in dramatic ... Treatment of infection may ameliorate symptom severity during the catarrhal phase of pertussis but has no effect on established ... Author(s): Langley JM, Halperin SA, Boucher FD, Smith B, Pediatric Investigators Collaborative Network on Infections in Canada ... The primary outcome measure was bacteriologic cure of infection as determined by cultures of nasopharyngeal aspirates. Culture- ...
Immune efficacy of five novel recombinant Bordetella bronchiseptica proteins | BMC Veterinary Research | Full Text
Currently, there is no vaccine to prevent these infections. To identify useful candidate antigens for such a vaccine, five B. ... The Gram-negative pathogen Bordetella bronchiseptica causes acute and chronic respiratory infection in a variety of animals. ... and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies. Clin ... Infection with and antibody response to Pasteurella multocida and Bordetella bronchiseptica in immature rabbits. Lab Anim Sci. ...
Code System Concept
Alison A. Weiss, PhD
Lethal infection by Bordetella pertussis mutants in the infant mouse model Infection and Immunity, 57 12, 3757-3764 ... Infection and immunity, 68 3, 1735-9. Craig-Mylius, K A; Weiss, A A 1999. Mutants in the ptlA-H genes of Bordetella pertussis ... Infection and immunity, 70 1, 403-6. Rambow-Larsen, Amy A; Weiss, Alison A 2002. The PtlE protein of Bordetella pertussis has ... Infection and immunity, 67 3, 1424-31. Fernandez, R C; Weiss, A A 1998. Serum resistance in bvg-regulated mutants of Bordetella ...
Original article(s) | Vlaams Diergeneeskundig Tijdschrift
The role of Bordetella bronchiseptica infections in respiratory disease in cats is not clear. In this study, the prevalence of ... The infection rate of animals younger than 6 months was similar to that of older cats. The bacterium was isolated more ... To determine the age at which a natural infection of turkey herpesvirus (HVT) occurs in turkeys, two studies were set up. A ... From the serological data obtained in the two studies, it was concluded that a natural infection of HVT takes shortly after ...
Whooping-coughParapertussisBacteriaInfantsBronchiseptica infectionsCanine parainfluenza virusRespiratory infection causedHinziiBacteriumVaccinePneumoniaCommonlyGram-negativePrevalenceTracheobronchitisImmunityDISEASESViral infectionEscherichiaBacteriologicLower airwayPrevention and ControlClinicalEfficacy2017UpperImmuneChronicExposureSecondaryInfectiousSeverityAntibioticsHUMANStudyPreventPracticesPatientsDataProtectionProvideChildren
Whooping-cough3
- Pertussis, or whooping cough, is an upper respiratory infection. (medlineplus.gov)
- OBJECTIVE: Although universal immunization against Bordetella pertussis (whooping cough) infection has resulted in dramatic reductions in the incidence of pertussis, outbreaks continue to occur in countries with excellent vaccine coverage. (druglib.com)
- Whooping cough (pertussis) is an infection of the airways caused by the bacteria Bordetella pertussis . (hopkinsallchildrens.org)
Parapertussis5
- Update on respiratory infection caused by Bordetella parapertussis. (nih.gov)
- Prevalence of Bordetella pertussis and Bordetella parapertussis in infants presenting to the emergency department with bronchiolitis. (medscape.com)
- however, B. parapertussis infection did occur. (who.int)
- Scientists suspect that other Bordetella species may have a role in causing milder infections and that by exchanging genes with B. pertussis and B. parapertussis , these species might enable their evolution and adaptation to humans and other animals. (nih.gov)
- Current diagnostic tests for pertussis detect only B. pertussis and B. parapertussis infections. (nih.gov)
Bacteria4
- Bordetella hinzii bacteria cause respiratory infections in birds and have been isolated from rodents on rare occasions ( 1 , 2 ). (cdc.gov)
- It is caused by the Bordetella pertussis bacteria. (medlineplus.gov)
- Infections with bacteria of the genus BORDETELLA . (nih.gov)
- To determine the range of effects of pertussis toxin (PT), NIAID-funded researchers at the University of Maryland School of Medicine genetically modified B. pertussis to be deficient in PT and compared the course of infection in mice infected with the modified bacteria to that of mice infected with the unmodified version. (nih.gov)
Infants2
- There were some severe cases of pertussis among infants caused mainly by B. pertussis and dual Bordetella infection. (who.int)
- In infants a pertussis infection is characterized by uncontrollable, violent coughing accompanied by a deep "whooping" sound when the patient tries to take a breath. (nih.gov)
Bronchiseptica infections1
- The role of Bordetella bronchiseptica infections in respiratory disease in cats is not clear. (ugent.be)
Canine parainfluenza virus4
- Many times, there is a viral infection with the canine parainfluenza virus followed by a secondary bacterial infection with Bordetella bronchiseptica. (beedogs.com)
- Non-core vaccines in Australia include those which provide protection against infections caused by canine parainfluenza virus, Bordetella bronchiseptica (these both contribute to kennel cough) and leptospirosis [ 1 , 2 ]. (rspca.org.au)
- The canine parainfluenza virus and Bordetella bronchiseptica vaccine (more commonly known together with the core vaccines as a C5 vaccine) is recommended for dogs who regularly come into contact with other dogs, such as on walks, at the park, day-care, puppy preschool, or boarding [ 3 ]. (rspca.org.au)
- If your veterinarian has recommended the canine parainfluenza virus and Bordetella bronchiseptica vaccine, this is usually given as a single intranasal vaccine (dripped into the nostrils, with the dog's head held slightly back), with your puppy's second core C3 vaccine, and then annually [ 1 , 2 ]. (rspca.org.au)
Respiratory infection caused1
- Pertussis is a highly communicable, acute bacterial respiratory infection caused by Bordetella pertussis . (cdc.gov)
Hinzii5
- Bordetella hinzii, a "new" opportunistic pathogen to think about. (nih.gov)
- Characteristics of Bordetella hinzii strains isolated from a cystic fibrosis patient over a 3-year period. (nih.gov)
- Study of a Bordetella hinzii isolate from a laboratory mouse. (nih.gov)
- Secondary Bordetella hinzii pneumonia in a patient with SARS-CoV-2 infection]. (nih.gov)
- We report 2 cases of pulmonary Bordetella hinzii infection in immunodeficient patients. (cdc.gov)
Bacterium2
Vaccine2
- Currently, there is no vaccine to prevent these infections. (biomedcentral.com)
- The development of a new vaccine is critical to the prevention and control of B. bronchiseptica infection. (biomedcentral.com)
Pneumonia1
- Infections with group B Streptococcus , Listeria monocytogenes , or gram-negative rods (eg, Escherichia coli , Klebsiella pneumoniae ) are common causes of bacterial pneumonia. (medscape.com)
Commonly2
- It should be emphasized that these guidelines represent the advice of CDC on questions commonly asked of the Hospital Infections Program, but are not intended to have the force of law or regulation. (cdc.gov)
- Upper respiratory tract infections (URIs) are commonly treated in family physicians' practices. (aafp.org)
Gram-negative1
- The Gram-negative pathogen Bordetella bronchiseptica causes acute and chronic respiratory infection in a variety of animals. (biomedcentral.com)
Prevalence1
- In this review, we summarised human and animal brucellosis, prevalence of infections in Nigeria, and economic impacts on production. (who.int)
Tracheobronchitis2
- One of the most common respiratory infections in dogs is Infectious tracheobronchitis, which is also known as kennel cough. (beedogs.com)
- Aerosolized antibiotics are helpful in selected cases of infectious tracheobronchitis (specifically those due to Bordetella infections), but are not appropriate as the sole therapy for pneumonic cases. (vin.com)
Immunity2
- 1. Fc receptor-mediated immunity against Bordetella pertussis. (nih.gov)
- The goal of vaccines is to build your pet's immunity against certain viruses, which either limit the severity of an infection or completely protect your pet from being infected. (wilsonsanimalhospital.com)
DISEASES3
- Infections are diseases caused by microorganisms and parasites. (nih.gov)
- In addition to helping scientists understand the levels of toxin involved during pertussis infection and the immune system response, the techniques used in this study may be applied to other toxins and other diseases. (nih.gov)
- Bordetella bronchiseptica is an important bacterial pathogen that causes a number of respiratory diseases in livestock and poultry. (biomedcentral.com)
Viral infection1
- This can happen with asthma or with the viral infection bronchiolitis . (hopkinsallchildrens.org)
Escherichia2
- He was hospitalized for 2 episodes of pulmonary infections in October 2012 and February-March 2013, during which Escherichia coli was isolated and for which he received ciprofloxacin. (cdc.gov)
- Intestinal organoids model human responses to infection by commensal and Shiga toxin producing Escherichia coli. (uc.edu)
Bacteriologic2
- We establish bacteriologic management of these infections and suggest therapeutic options if needed. (cdc.gov)
- The primary outcome measure was bacteriologic cure of infection as determined by cultures of nasopharyngeal aspirates. (druglib.com)
Lower airway1
- Amoxicillin or amoxicillin/clavulanate, cephalosporins, doxycycline, potentiated sulfas, and especially the fluoroquinolones are good choices for lower airway infections. (vin.com)
Prevention and Control1
- The Guideline for Infection Control in Hospital Personnel is part of the Guidelines for Prevention and Control of Nosocomial Infections. (cdc.gov)
Clinical4
- GlobalData's clinical trial report, 'Bordetella Pertussis Infections Global Clinical Trials Review, H2, 2014' provides data on the Bordetella Pertussis Infections clinical trial scenario. (clickpress.com)
- This report provides elemental information and data relating to the clinical trials on Bordetella Pertussis Infections. (clickpress.com)
- The databook offers a preliminary coverage of disease clinical trials by their phase, trial status, prominence of the sponsors and also provides briefing pertaining to the number of trials for the key drugs for treating Bordetella Pertussis Infections. (clickpress.com)
- We describe 4 rapidly fatal cases of potentially donor-derived invasive mold infections in the United States, highlighting the importance of maintaining clinical suspicion for these infections in transplant recipients. (cdc.gov)
Efficacy1
- Each guideline begins with a preamble that describes the approaches that have been used or advocated to deal with infection control issues and evaluate, where data exist, their efficacy. (cdc.gov)
20171
- Using a large US hospital database, we describe 192 Candida aurisassociated hospitalizations during 2017-2022, including 38 (20%) C. auris bloodstream infections. (cdc.gov)
Upper4
- The initial (catarrhal) phase is indistinguishable from common upper respiratory infections. (medscape.com)
- A more recent article on antibiotic use in acute upper respiratory tract infections is available. (aafp.org)
- Upper respiratory tract infections account for millions of visits to family physicians each year in the United States. (aafp.org)
- This article outlines the guidelines and indications for appropriate antibiotic use for common upper respiratory infections. (aafp.org)
Immune1
- If your pet gets exposed to the virus they're vaccinated against, it will trigger an immune response where they're body fights against the infection. (wilsonsanimalhospital.com)
Chronic1
- Asthma, allergies , or a chronic infection in the sinuses or airways also might cause lasting coughs. (hopkinsallchildrens.org)
Exposure1
- This is based on an assessment of the dog's location, lifestyle, and risk of exposure to the infection [ 1 , 2 ]. (rspca.org.au)
Secondary1
- Antibiotics may be recommended to prevent secondary bacterial infections. (beedogs.com)
Infectious1
- According to vet professionals, this is a highly contagious infection caused by a combination of infectious agents. (beedogs.com)
Severity1
- Treatment of infection may ameliorate symptom severity during the catarrhal phase of pertussis but has no effect on established paroxysms, emesis, or apnea if given during the paroxysmal or convalescent phases. (druglib.com)
Antibiotics1
- A handout on antibiotic use is available at https://familydoctor.org/familydoctor/en/drugs-procedures-devices/prescription-medicines/antibiotics-when-they-can-and-cant-help.html . (aafp.org)
HUMAN1
- 16. Intracellular survival of virulent Bordetella pertussis in human polymorphonuclear leukocytes. (nih.gov)
Study3
- In May 2013, NIAID grantees at the University of Virginia published a study that measured the quantities of ACT at various stages of infection. (nih.gov)
- These results provide up-to-date information on TB infection among study subpopulations. (cdc.gov)
- To determine risk factors for non-O157 STEC infection, we enrolled 939 patients and 2,464 healthy controls in a case-control study conducted in 10 US sites. (cdc.gov)
Prevent1
- Erythromycin, recommended for treatment of pertussis to prevent transmission of infection, is poorly tolerated because of gastrointestinal side effects. (druglib.com)
Practices1
- To address these last 2 types of practices, realizing that hospitals must make decisions in the absence of definitive data, we have sought the advice of working groups composed of non-CDC experts with broad experience in infection control. (cdc.gov)
Patients2
- In addition, respondents were asked how likely they were to consider pertussis infection in patients with prolonged cough before 2012 and currently. (cdc.gov)
- La culture de type classique a permis d'identifier Neissera meningitidis chez 37 (18,9 %) des 196 patients ayant des symptômes et des signes cliniques de méningite, ce qui a ensuite été confirmé par réaction en chaîne par polymérase. (who.int)
Data1
- From the serological data obtained in the two studies, it was concluded that a natural infection of HVT takes shortly after hatching, within the first days of life. (ugent.be)
Protection1
- 2. Immunoglobulin A-mediated protection against Bordetella pertussis infection. (nih.gov)
Provide1
- The CDC guidelines were developed to provide a central reference for professionals involved in infection control that contains CDC recommendations and is easily accessible to the infection control personnel in hospitals. (cdc.gov)
Children1
- DTaP vaccination , one of the recommended childhood immunizations, protects children against pertussis infection. (medlineplus.gov)