Bordetella bronchiseptica: A species of BORDETELLA that is parasitic and pathogenic. It is found in the respiratory tract of domestic and wild mammalian animals and can be transmitted from animals to man. It is a common cause of bronchopneumonia in lower animals.Bordetella: A genus of gram-negative, aerobic bacteria whose cells are minute coccobacilli. It consists of both parasitic and pathogenic species.Bordetella Infections: Infections with bacteria of the genus BORDETELLA.Bordetella pertussis: A species of gram-negative, aerobic bacteria that is the causative agent of WHOOPING COUGH. Its cells are minute coccobacilli that are surrounded by a slime sheath.Rhinitis, Atrophic: A chronic inflammation in which the NASAL MUCOSA gradually changes from a functional to a non-functional lining without mucociliary clearance. It is often accompanied by degradation of the bony TURBINATES, and the foul-smelling mucus which forms a greenish crust (ozena).Bordetella parapertussis: A species of BORDETELLA with similar morphology to BORDETELLA PERTUSSIS, but growth is more rapid. It is found only in the RESPIRATORY TRACT of humans.Virulence Factors, Bordetella: A set of BACTERIAL ADHESINS and TOXINS, BIOLOGICAL produced by BORDETELLA organisms that determine the pathogenesis of BORDETELLA INFECTIONS, such as WHOOPING COUGH. They include filamentous hemagglutinin; FIMBRIAE PROTEINS; pertactin; PERTUSSIS TOXIN; ADENYLATE CYCLASE TOXIN; dermonecrotic toxin; tracheal cytotoxin; Bordetella LIPOPOLYSACCHARIDES; and tracheal colonization factor.Turbinates: The scroll-like bony plates with curved margins on the lateral wall of the NASAL CAVITY. Turbinates, also called nasal concha, increase the surface area of nasal cavity thus providing a mechanism for rapid warming and humidification of air as it passes to the lung.Pertussis Vaccine: A suspension of killed Bordetella pertussis organisms, used for immunization against pertussis (WHOOPING COUGH). It is generally used in a mixture with diphtheria and tetanus toxoids (DTP). There is an acellular pertussis vaccine prepared from the purified antigenic components of Bordetella pertussis, which causes fewer adverse reactions than whole-cell vaccine and, like the whole-cell vaccine, is generally used in a mixture with diphtheria and tetanus toxoids. (From Dorland, 28th ed)Swine Diseases: Diseases of domestic swine and of the wild boar of the genus Sus.Pasteurella multocida: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria normally found in the flora of the mouth and respiratory tract of animals and birds. It causes shipping fever (see PASTEURELLOSIS, PNEUMONIC); HEMORRHAGIC BACTEREMIA; and intestinal disease in animals. In humans, disease usually arises from a wound infection following a bite or scratch from domesticated animals.Siderophores: Low-molecular-weight compounds produced by microorganisms that aid in the transport and sequestration of ferric iron. (The Encyclopedia of Molecular Biology, 1994)Hemagglutinins: Agents that cause agglutination of red blood cells. They include antibodies, blood group antigens, lectins, autoimmune factors, bacterial, viral, or parasitic blood agglutinins, etc.Nasal Cavity: The proximal portion of the respiratory passages on either side of the NASAL SEPTUM. Nasal cavities, extending from the nares to the NASOPHARYNX, are lined with ciliated NASAL MUCOSA.Pasteurella Infections: Infections with bacteria of the genus PASTEURELLA.Dermotoxins: Specific substances elaborated by plants, microorganisms or animals that cause damage to the skin; they may be proteins or other specific factors or substances; constituents of spider, jellyfish or other venoms cause dermonecrosis and certain bacteria synthesize dermolytic agents.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Bacterial Outer Membrane Proteins: Proteins isolated from the outer membrane of Gram-negative bacteria.Bacterial Proteins: Proteins found in any species of bacterium.Bordetella avium: A species of BORDETELLA isolated from the respiratory tracts of TURKEYS and other BIRDS. It causes a highly contagious bordetellosis.Gene Expression Regulation, Bacterial: Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.Adenylate Cyclase Toxin: One of the virulence factors produced by virulent BORDETELLA organisms. It is a bifunctional protein with both ADENYLYL CYCLASES and hemolysin components.Bacterial Adhesion: Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.Pasteurella: The oldest recognized genus of the family PASTEURELLACEAE. It consists of several species. Its organisms occur most frequently as coccobacillus or rod-shaped and are gram-negative, nonmotile, facultative anaerobes. Species of this genus are found in both animals and humans.Antibodies, Bacterial: Immunoglobulins produced in a response to BACTERIAL ANTIGENS.Respiratory Tract Infections: Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.Adhesins, Bacterial: Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.Pertussis Toxin: One of the virulence factors produced by BORDETELLA PERTUSSIS. It is a multimeric protein composed of five subunits S1 - S5. S1 contains mono ADPribose transferase activity.Trachea: The cartilaginous and membranous tube descending from the larynx and branching into the right and left main bronchi.Virulence: The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.Hemagglutination: The aggregation of ERYTHROCYTES by AGGLUTININS, including antibodies, lectins, and viral proteins (HEMAGGLUTINATION, VIRAL).Genes, Bacterial: The functional hereditary units of BACTERIA.Whooping Cough: A respiratory infection caused by BORDETELLA PERTUSSIS and characterized by paroxysmal coughing ending in a prolonged crowing intake of breath.Bacterial Vaccines: Suspensions of attenuated or killed bacteria administered for the prevention or treatment of infectious bacterial disease.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Respiratory System: The tubular and cavernous organs and structures, by means of which pulmonary ventilation and gas exchange between ambient air and the blood are brought about.Fimbriae, Bacterial: Thin, hairlike appendages, 1 to 20 microns in length and often occurring in large numbers, present on the cells of gram-negative bacteria, particularly Enterobacteriaceae and Neisseria. Unlike flagella, they do not possess motility, but being protein (pilin) in nature, they possess antigenic and hemagglutinating properties. They are of medical importance because some fimbriae mediate the attachment of bacteria to cells via adhesins (ADHESINS, BACTERIAL). Bacterial fimbriae refer to common pili, to be distinguished from the preferred use of "pili", which is confined to sex pili (PILI, SEX).Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Transglutaminases: Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Hydroxamic Acids: A class of weak acids with the general formula R-CONHOH.Alcaligenes: A genus of gram-negative, aerobic, motile bacteria that occur in water and soil. Some are common inhabitants of the intestinal tract of vertebrates. These bacteria occasionally cause opportunistic infections in humans.Copyright: It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Equipment Reuse: Further or repeated use of equipment, instruments, devices, or materials. It includes additional use regardless of the original intent of the producer as to disposability or durability. It does not include the repeated use of fluids or solutions.Quality Control: A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)Polymyxin B: A mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.Colistin: Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.Polymyxins: Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.Cats: The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing): An enzyme that catalyzes the synthesis of fructose-6-phosphate plus GLUTAMINE from GLUTAMATE plus glucosamine-6-phosphate.Transaminases: A subclass of enzymes of the transferase class that catalyze the transfer of an amino group from a donor (generally an amino acid) to an acceptor (generally a 2-keto acid). Most of these enzymes are pyridoxyl phosphate proteins. (Dorland, 28th ed) EC 2.6.1.Prephenate Dehydrogenase: An enzyme that catalyzes the conversion of prephenate to p-hydroxyphenylpyruvate in the presence of NAD. In the enteric bacteria, this enzyme also possesses chorismate mutase activity, thereby catalyzing the first two steps in the biosynthesis of tyrosine. EC 1.3.1.12.

Probing the function of Bordetella bronchiseptica adenylate cyclase toxin by manipulating host immunity. (1/244)

We have examined the role of adenylate cyclase-hemolysin (CyaA) by constructing an in-frame deletion in the Bordetella bronchiseptica cyaA structural gene and comparing wild-type and cyaA deletion strains in natural host infection models. Both the wild-type strain RB50 and its adenylate cyclase toxin deletion (DeltacyaA) derivative efficiently establish persistent infections in rabbits, rats, and mice following low-dose inoculation. In contrast, an inoculation protocol that seeds the lower respiratory tract revealed significant differences in bacterial numbers and in polymorphonuclear neutrophil recruitment in the lungs from days 5 to 12 postinoculation. We next explored the effects of disarming specific aspects of the immune system on the relative phenotypes of wild-type and DeltacyaA bacteria. SCID, SCID-beige, or RAG-1(-/-) mice succumbed to lethal systemic infection following high- or low-dose intranasal inoculation with the wild-type strain but not the DeltacyaA mutant. Mice rendered neutropenic by treatment with cyclophosphamide or by knockout mutation in the granulocyte colony-stimulating factor locus were highly susceptible to lethal infection by either wild-type or DeltacyaA strains. These results reveal the significant role played by neutrophils early in B. bronchiseptica infection and by acquired immunity at later time points and suggest that phagocytic cells are a primary in vivo target of the Bordetella adenylate cyclase toxin.  (+info)

Genetic basis for lipopolysaccharide O-antigen biosynthesis in bordetellae. (2/244)

Bordetella bronchiseptica and Bordetella parapertussis express a surface polysaccharide, attached to a lipopolysaccharide, which has been called O antigen. This structure is absent from Bordetella pertussis. We report the identification of a large genetic locus in B. bronchiseptica and B. parapertussis that is required for O-antigen biosynthesis. The locus is replaced by an insertion sequence in B. pertussis, explaining the lack of O-antigen biosynthesis in this species. The DNA sequence of the B. bronchiseptica locus has been determined and the presence of 21 open reading frames has been revealed. We have ascribed putative functions to many of these open reading frames based on database searches. Mutations in the locus in B. bronchiseptica and B. parapertussis prevent O-antigen biosynthesis and provide tools for the study of the role of O antigen in infections caused by these bacteria.  (+info)

Bordetella bronchiseptica infection in human immunodeficiency virus-infected patients. (3/244)

Bordetella bronchiseptica is a pleomorphic gram-negative coccobacillus that commonly causes respiratory tract infections in dogs. We identified nine human immunodeficiency virus (HIV)-infected persons with culture-confirmed B. bronchiseptica infections (eight respiratory tract and one disseminated infection). The respiratory illnesses ranged in severity from mild upper respiratory tract infection to pneumonia. All nine patients had had at least one AIDS-defining condition before the B. bronchiseptica infection. Two patients had household contact with dogs before their illnesses, and one had household contact with cats. Infection due to B. bronchiseptica is uncommon in HIV-infected persons. Additional data are needed to fully define the spectrum of disease due to B. bronchiseptica infections and to evaluate the possibility that this infection may be acquired from pets. Treatment of B. bronchiseptica infection should be tailored to the patient and should be based on the results of susceptibility testing.  (+info)

Essential role of the iron-regulated outer membrane receptor FauA in alcaligin siderophore-mediated iron uptake in Bordetella species. (4/244)

Phenotypic analysis using heterologous host systems localized putative Bordetella pertussis ferric alcaligin transport genes and Fur-binding sequences to a 3.8-kb genetic region downstream from the alcR regulator gene. Nucleotide sequencing identified a TonB-dependent receptor family homolog gene, fauA, predicted to encode a polypeptide with high amino acid sequence similarity with known bacterial ferric siderophore receptors. In Escherichia coli, the fauA genes of both B. pertussis and Bordetella bronchiseptica directed the production of a 79-kDa polypeptide, approximating the predicted size of the mature FauA protein. B. bronchiseptica fauA insertion mutant BRM17 was unable to utilize ferric alcaligin, and in complementation analyses ferric alcaligin utilization was restored to this mutant by supplying the wild-type fauA gene in trans. Mutant BRM18, carrying a nonpolar in-frame fauA deletion mutation, was defective in ferric alcaligin utilization and (55)Fe-ferric alcaligin uptake and no longer produced a 79-kDa iron-regulated outer membrane protein. In complementation analyses, BRM18 merodiploids bearing the wild-type fauA gene in trans regained ferric alcaligin siderophore transport and utilization functions and produced the 79-kDa protein. Analysis of a plasmid-borne fauA-lacZ operon fusion confirmed that fauA is subject to iron regulation at the transcriptional level and that cis-acting transcriptional control elements mediating fauA iron repressibility reside within the 3.8-kb PstI fauA DNA region. Moreover, expression of the fauA-lacZ fusion gene under iron starvation conditions was shown to be alcR dependent. FauA is a 79-kDa iron-regulated outer membrane receptor protein required for transport and utilization of ferric alcaligin siderophore complexes by Bordetella species.  (+info)

Disruption of tonB in Bordetella bronchiseptica and Bordetella pertussis prevents utilization of ferric siderophores, haemin and haemoglobin as iron sources. (5/244)

The Bordetella bronchiseptica tonB gene was cloned by detection of a chromosomal restriction fragment hybridizing with each of two degenerate oligonucleotides that corresponded to Pro-Glu and Pro-Lys repeats characteristic of known TonB proteins. The tonB(Bb) gene was situated upstream of exbB and exbD homologues and downstream of a putative Fur-regulated promoter. Hybridization results indicated that the tonB operon and flanking regions were highly conserved between B. bronchiseptica, Bordetella pertussis and Bordetella parapertussis. Disruption of tonB in B. bronchiseptica resulted in inability to grow in iron-limiting media, and inability to utilize alcaligin, enterobactin, ferrichrome, desferroxamine B, haemin and haemoglobin. Although it was not possible to inactivate tonB in a clinical B. pertussis isolate, tonB was disrupted in a laboratory B. pertussis strain previously selected for the ability to grow on Luria-Bertani medium. This B. pertussis tonB mutant shared a similar iron complex utilization deficient phenotype with the B. bronchiseptica tonB mutant. The B. bronchiseptica tonB operon present on a plasmid did not complement an Escherichia coli tonB mutant, but inefficient reconstitution of enterobactin utilization was observed in one fepA mutant harbouring plasmid copies of the B. pertussis fepA homologue and tonB(Bb) operon.  (+info)

Bordetella bronchiseptica-mediated cytotoxicity to macrophages is dependent on bvg-regulated factors, including pertactin. (6/244)

The effect of Bordetella bronchiseptica infection on the viability of murine macrophage-like cells and on primary porcine alveolar macrophages was investigated. The bacterium was shown to be cytotoxic for both cell types, particularly where tight cell-to-cell contacts were established. In addition, bvg mutants were poorly cytotoxic for the eukaryotic cells, while a prn mutant was significantly less toxic than wild-type bacteria. B. bronchiseptica-mediated cytotoxicity was inhibited in the presence of cytochalasin D or cycloheximide, an inhibitor of microfilament-dependent phagocytosis or de novo eukaryotic protein synthesis, respectively. The mechanism of eukaryotic cell death was examined, and cell death was found to occur primarily through a necrotic pathway, although a small proportion of the population underwent apoptosis.  (+info)

Pregenomic comparative analysis between bordetella bronchiseptica RB50 and Bordetella pertussis tohama I in murine models of respiratory tract infection. (7/244)

We describe here a side-by-side comparison of murine respiratory infection by Bordetella pertussis and Bordetella bronchiseptica strains whose genomes are currently being sequenced (Tohama I and RB50, respectively). B. pertussis and B. bronchiseptica are most appropriately classified as subspecies. Their high degree of genotypic and phenotypic relatedness facilitates comparative studies of pathogenesis. RB50 and Tohama I differ in their abilities to grow in the nose, trachea, and lungs of BALB/c mice and to induce apoptosis, lung pathology, and an antibody response. To focus on the interactions between the bacteria and particular aspects of the host immune response, we used mice with specific immune defects. Mice lacking B cells and T cells were highly susceptible to B. bronchiseptica and were killed by intranasal inoculation with doses as low as 500 CFU. These mice were not killed by B. pertussis, even when doses as high as 10(5) CFU were delivered to the lungs. B. bronchiseptica, which was highly resistant to naive serum in vitro, caused bacteremia in these immunodeficient mice, while B. pertussis, which was highly sensitive to naive serum, did not cause bacteremia. B. bronchiseptica was, however, killed by immune serum in vitro, and adoptive transfer of anti-Bordetella antibodies protected SCID-beige mice from B. bronchiseptica lethal infection. Neutropenic mice were similarly killed by B. bronchiseptica but not B. pertussis infection, suggesting neutrophils are critical to the early inflammatory response to the former but not the latter. B. bronchiseptica was dramatically more active than B. pertussis in mediating the lysis of J774 cells in vitro and in inducing apoptosis of inflammatory cells in mouse lungs. This side-by-side comparison describes phenotypic differences that may be correlated with genetic differences in the comparative analysis of the genomes of these two highly related organisms.  (+info)

Polymorphism in the pertussis toxin promoter region affecting the DNA-based diagnosis of Bordetella infection. (8/244)

The pertussis toxin (PT) promoter region is a frequently used target for DNA-based diagnosis of pertussis and parapertussis infections. The reported polymorphism in this region has also allowed discrimination of species in mixtures with several Bordetella species by their specific PCR amplicon restriction patterns. In the present study, we investigated the degree of polymorphism in order to confirm the reliability of the assay. Five different sequence types of the amplified 239- or 249-bp region were found among the 33 Bordetella pertussis, B. parapertussis, and B. bronchiseptica American Type Culture Collection reference strains and patient isolates analyzed. According to the sequences that were obtained and according to the PT promoter sequences already available in the databases, restriction enzyme analysis with TaqI, BglI, and HaeII, which gave four different patterns, can be performed to reliably identify B. pertussis, B. parapertussis, and B. bronchiseptica.  (+info)

Adler K, Radeloff I, Stephan B, Greife H, Helelmann K. Bacteriological and virological status in upper respiratory tract infections of cats. Berl.Munch.Tierarztl.Wochenschr. 2007;120 (3-4):120-125.. Veir JK, Ruch-Gallie R, Spindel ME, Lappin MR. Prevalence of selected infectious organisms and comparisons of two anatomic sampling sites in shelter cats with upper respiratory tract diseases. J.Feline Med. Surg. 2008;10(6):551-557.. Schwarz S, Alesik E, Grobbel M, Lübke-Becker A, Werckenthin C, Wieler LH, et al. Antimicrobial susceptibility of Pasteurella multocida and Bordetella bronchiseptica from dogs and cats as determined in the BfT-GermVet monitoring program 2004-2006. Berl. Munch.Tierarztl.Wochenschr. 2007;120(9-10): 423-430.. Bauwens JE, Spach DH, Schacker TW, Mustafa MM, Bowden RA. Bordetella bronchiseptica pneumonia and bacteremia following bone marrow transplantation. J Clin Microbiol 1992;30: 2474-5.. Binns SH, Dawson S, Speakman AJ, et al. Prevalence and risk factors or feline ...
Bordetella bronchiseptica ATCC ® BAA-588D-5™ Designation: Genomic DNA from Bordetella bronchiseptica strain RB50 TypeStrain=False Application:
Coloured scanning electron micrograph (SEM) of Bordetella bronchiseptica, Gram-negative, aerobic, motile, coccobacillus prokaryote (bacterium). Bordetella bronchiseptica typically infects the respiratory tracts of smaller mammals (cats, dogs, rabbits). It causes infectious bronchitis, but rarely infects humans. It does not express pertussis toxin, which is one of the characteristic virulence factors of B. pertussis. It is related to Bordetella pertussis, the obligate human pathogen, that causes pertussis or whooping cough. B. bronchiseptica does not express pertussis toxin, which is one of the characteristic virulence factors of B. pertussis. Humans are not natural carriers of B. bronchiseptica. Magnification: x4,400 when shortest axis printed at 25 millimetres. - Stock Image C032/2756
DEMONSTRATION OF ONE YEAR DURATION-OF-IMMUNITY FOR A FELINE BORDETELLA BRONCHISEPTICA VACCINE. J.R. Williams, R. Laris. OBJECTIVE: The objective of this study was to determine the ability of a modified live intranasal Bordetella bronchiseptica vaccine (Nobivac-Bb) to prevent disease in cats for a period of one year following vaccination. EXPERIMENTAL DESIGN: Forty-eight cats were vaccinated according to manufacturers instructions. Twenty-four vaccinated cats and 12 controls were challenged with a virulent strain of B. bronchiseptica six-months after vaccination, and two additional groups of vaccinates and controls were challenged one year after vaccination. Clinical signs were recorded daily for two weeks after challenge, and clinical scores were calculated for each group. The Mann-Whitney U test was used to determine if clinical scores in the vaccinated groups were significantly different from scores in the control groups. RESULTS: The mean clinical score for vaccinated cats at six-months ...
Nobivac Feline-Bb is for the intranasal vaccination of healthy kittens and cats for prevention of disease caused by Bordetella bronchiseptica. B. bronchiseptica acts as a primary or secondary pathogen in feline respiratory disease.
Twelve specific pathogen-free (SPF) puppies were vaccinated intranasally with a bivalent, modified live vaccine against infectious tracheobronchitis (group 1) and six puppies of the same age and from the same source served as unvaccinated controls (group 2). Both groups were challenged with wild-type Bordetella bronchiseptica and canine parainfluenza virus by the aerosol route 56 weeks after group 1 had been vaccinated, and at the same time six 10-week-old SPF puppies from the same source (group 3) were also challenged. Oronasal swabs were taken regularly before and after the challenge, for the isolation of bacteria and viruses, and the dogs were observed for clinical signs for three weeks after the challenge. The control dogs became culture-positive for B bronchiseptica and canine parainfluenza virus, but the isolation yields from the vaccinated group were significantly lower (P,0·05). The mean clinical scores of the vaccinated group were 61 per cent lower than the scores of group 2 ...
Bordetella bronchiseptica ATCC ® 10580™ Designation: 03127 TypeStrain=False Application: Media testing Quality control strain Quality control strain for BBL and bioMérieux Vitek products Food testing
5] Binns, S. H., Corkill, J. E., Dawson, S., Gaskell, R. M., Hart, C. A., Kariuki, S., Osborn, A. M., Saunders, J. R., and Speakman, A. J. 1997. Characterization of antibiotic resistance plasmids from "Bordetella bronchiseptica". "Journal of Antimicrobial Chemotherapy". 40: 811-816. [[6] Appel J. G. M., Bemis, A. D., and Greisen, A. H. 1977. Pathogenesis of canine bordetellosis. "The Journal of Infectious Diseases". 135: 753-762. [[7] Vanderzee, A, Mooi, F., Emben, J. V., and Musser, J. Molecular evolution and host adaptation of "Bordetella" spp.: phylogenetic analysis using multilocus enzyme electrophoresis and typing with three insertion sequences. 1997. "Journal of Bacteriology". 179: 6609-6617. [[8] Roberts, M., and Stevenson, A. 2003. Use of "Bordetella bronchiseptica" and "Bordetella pertussis" as live vaccines and vectors for heterologous antigens. "FEMS Immunology and Medical Microbiology". 37: 121-128. [[9] Arico, B. and Rappuoli, R. "Bordetella parapertussis" and "Bordetella ...
Both virus and bacterial causes of kennel cough are spread through the air by infected dogs sneezing and coughing. It can also spread through contact with contaminated surfaces and through direct contact. It is highly contagious, even days or weeks after symptoms disappear. Symptoms begin usually two to three days after exposure,[2] and can progress to pneumonia. Various studies have shown that kennel cough is a zoonotic disease, meaning it can transfer from animal to human and vice versa. These studies indicate that Bordetella bronchiseptica infections in humans are uncommon and generally occur in immunocompromised individuals ...
Dr. Burns conducts undergraduate research in the area of microbiology. Students in his lab has performed projects studying interaction of Bordetella bronchiseptica with animal cells, prevalence of Bordetella species in the wild animal population, host specificity of Bordetella bronchiseptica, matrix metalloprotease activation by Group A Streptococcus, coliforms in the Olentangy River Wetlands Research Park, and carriage of Streptococcus pyogenes among Shawnee State University students. Undergraduate students have presented their research at the American Society for Microbiology general meeting, the Ohio Academy of Sciences Annual Meeting, the Beta Beta Beta Biological Honor Society District Convention, and the Celebration of Scholarship Undergraduate Conference, supported by funds from the Department of Natural Sciences, the CAS Deans Office, and the Board of Trustees Award. ...
Replied on 04/19/2011 If she hasnt been vaccinated within the past 6 months she may not be protected as immunity wanes quickly with this particular vaccine. Even if she has been vaccinated recently Bordetella Bronchiseptica is a bacterium that is only part of the complex of pathogens that can cause "Kennel Cough" . Other components can include Adenovirus, Parainfluenza virus , Mycoplasma and occasionally Herpes virus. The most common cause of Kennel Cough is a combination of Parainfluenza virus and Bordetella Bronchiseptica . We vaccinate against the most common strains of Bordetella and the Parainfluenza virus but there are many variants of Bordetella and we cant vaccinate against them all. The good news is that because she was vaccinated some immunity memory is present and she probably wont get as sick as she would have without the vaccine. Keep her as quiet as possible as exercise worsens the cough. Watch her for lethargy, lack of appetite or a cough that interferes with her sleeping. If ...
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
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A syndrome reported in the USA and Europe, typically affecting multiple cats in a group,3 but individual cats too.4 Associated with high mortality (30-50%), interestingly especially in adult cats. Clinical signs include facial and paw cutaneous oedema and ulceration, bruising, pyrexia, icterus and cat flu signs.. Chlamydophila felis. C. felis is a common cause of conjunctivitis, especially in young (, 1 year of age) cats.5 Conjunctivitis, ocular discharge (initially serous and unilateral, then mucopurulent and bilateral) and chemosis are seen, but corneal ulceration is not a feature. Occasionally may see sneezing and a nasal discharge too.. Mycoplasma spp. and Bordetella bronchiseptica. Both Mycoplasma spp. and B. bronchiseptica can be found in normal cats, but have also been associated with disease. Mycoplasma spp. can cause conjunctivitis, and an association with URTD has been reported,6 whilst B. bronchiseptica can cause ocular and nasal discharge, sneezing, pyrexia ± coughing.7. Carrier ...
Eight collie-cross pups, eight weeks old, were inoculated intramuscularly with an aluminum hydroxide adjuvanted preparation of killed Bordetella bronchiseptica; the inoculation was repeated after two weeks. Two weeks after the second inoculation, the vaccinated dogs and a control group of four unvaccinated animals were placed in contact with a group of five pups of similar age which had been experimentally infected with a pathogenic strain of B bronchiseptica by an aerosol method. All four unvaccinated control dogs as well as all five experimentally infected dogs developed a respiratory disease characterised by persistent coughing. Six of the vaccinated dogs remained free from clinical respiratory disease while disease was less severe and of shorter duration in the remaining two than in controls. Only slight changes were found in the lungs of vaccinated animals at necropsy while in the controls there was a severe tracheobronchitis. There was a marked reduction in the numbers of B bronchiseptica ...
Bordetella pertussis (whooping cough) - "no known animal or environmental reservoir" (Mattoo and Cherry 2005 - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1082800/ ). Bordetella bronchiseptica, B. parapertussis, and B. holmesii are "associated with respiratory infections in humans and other mammals" - B. bronchiseptica is "a major cause of kennel cough in dogs" (Mattoo and Cherry 2005 - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1082800/ ). Polio can infect primates: http://jid.oxfordjournals.org/content/175/Supplement_1/S286.full.pdf. Measles: "no animal or environmental reservoir is known to exist" however "Many primate species are susceptible to measles virus infection" http://jid.oxfordjournals.org/content/204/suppl_1/S47.full.pdf+html. Cholera: aquatic plants, animals, and sediments (zzoplankton largest known) http://onlinelibrary.wiley.com/doi/10.1111/j.1758-2229.2009.00128.x/abstract. "Humans are the only natural reservoir for N. ...
Cavitary Pneumonia in an AIDS Patient Caused by an Unusual Bordetella bronchiseptica Variant Producing Reduced Amounts of Pertactin and Other Major Antigens: Al
An inner ear infection may have started with an outer ear infection, which remained unnoticed and untreated and gradually worked its way into the inner ear, or with a middle ear infection, which resulted from an upper respiratory infection. Or it may have arisen from bacteria in the nasal cavity or bloodstream. A radiograph of the head may help determine if the middle ears are affected. Some of the bacteria which have been cultured from ear infections are Staphylococcus sp, Pseudomonas aeruginosa, Pasteurella multocida, Bordetella bronchiseptica, Proteus mirabilis, Streptoccus epidermidis, Bacteroides spp. and Escherichia coli.. Treatment needs to be aggressive and prolonged. If exudate (pus) is found deep in the ear canal, a culture and sensitivity should be done in order to determine the bacterial agent and which antibiotics will be most effective in eliminating the infection. However, if it is impossible to access the bacteria in order to do the culture, many veterinarians will opt to treat ...
This study demonstrates that pig Oral Fluid may contain genetic material of Bordetella bronchiseptica (Bb) and Pasteurella multocida (PMT), which is detectable by qPCR. The detection rate was similar in OF and NS from the same animal or group of animals. These results suggest that OF could be used for monitoring of AR in pigs, reducing labor and animal stress during sample collection, and providing valuable information about the health status of breeding and growing pigs in regards to AR. The findings also suggest that there may be a significant proportion of pigs free from Bb infection, although it is considered a normal inhabitant of the respiratory tract in pigs. ...
Jangkitan bermula dari luar telinga dan terus ke dalam telinga. Atau terdapat bakteria didalam mulut atau salur darah. Dengan menggunakan radiograph dibahagian kepala ia akan dapat dikenalpasti. Beberapa bakteria tersebut ialah Staphylococcus sp, Pseudomonas aeruginosa, Pasteurella multocida, Bordetella bronchiseptica, Proteus mirabilis, Streptococcus epidermidis, Bacteroides spp. and Escherichia Coli. ...
Many 5 or 7-way vaccines that vets will often recommend for puppies can help prevent parainfluenza and other infections that tend to complicate kennel cough infections and bring on more severe symptoms. A vaccine against both parainfluenza and Bordetella bronchiseptica can also be given to puppies to provide a large amount of protection against kennel cough. Side effects of this vaccine can include the appearance of symptoms similar to kennel cough which clear up within a few days, often without treatment. The parainfluenza virus can be spread to other pets for up to 3 or 4 days after vaccination, so keeps your dog isolated from other dogs after the vaccine is administered. ...
Non-core vaccinations include that for Bordetella bronchiseptica, which is usually required by boarding facilities, obedience classes, dog shows and other places where the highly contagious kennel cough can spread. If your dog is often exposed to bodies of water -- ranging from streams to lakes -- your vet may recommend a vaccine against leptospirosis. This bacterial infection, which can prove fatal in some cases, is also spread via contaminated urine and can remain in the soil. If you travel a lot with your pet, or participate in dog shows, the canine influenza virus vaccine is recommended. While a vaccine is available for Lyme disease, many vets dont suggest it for their patients unless the dogs lifestyle puts him at particular risk for this debilitating disease.. ...
CRP is one of the proteins commonly referred to as acute phase reactants. CRP is distinguished by its rapid response to trauma or infection. Increased CRP levels have been found in dogs with arthritis, procitis or thrombophlebitis. Dogs with an increased number of leukocytes had significantly higher CRP levels than dogs with non-inflammatory leukograms. In addition, increased CRP levels have been documented in dogs infected with Ehrlichia canis or Bordetella bronchiseptica. ...
In healthy adult dogs, B. bronchiseptica typically causes no more than a mild illness. In puppies or in dogs with other underlying health issues, however, it can cause severe illness or even death in rare cases.. Diagnosis and Treatment. Although sophisticated testing is available, diagnosis is generally based on a history of exposure to infected dogs or a recent visit to a kennel, combined with the presence of signs of illness. In mild cases, treatment is generally supportive, as the disease typically resolves on its own unless a subsequent infection occurs. Precautionary antibiotics to prevent subsequent infection may be prescribed. In severe cases, treatment may consist of administration of antibiotics as well as medications to help your pet breathe more easily. Cough medication may also be prescribed if appropriate.. A harness, rather than a collar, is recommended for leash walking of ill dogs. A traditional collar puts pressure on already sensitive and irritated tracheal tissues and can ...
CT Beer Trail website (ctbeertrail.net) estimates that close to 15 brewing businesses have opened since 2010. News and events website serves as a gathering place for members and fans. Tastings and onsite tours at breweries draw fans as well.. ...
Today, Doctor Eye Health is going to cover the three artificial tears that address all three layers of the tear film. Learn about the top 3 best eye drops here.
Using antisera raised against serotype 2 and 3 fimbrial subunits from Bordetella pertussis, serologically related polypeptides were detected in Bordetella bronchiseptica, Bordetella parapertussis and Bordetella avium strains. The two B. pertussis fimbrial subunits, and three of the serologically related B. bronchiseptica polypeptides, were shown to be very similar in amino ... read more acid composition and N-terminal amino acid sequence. Homology was observed between the N-termini of these polypeptides, and fimbrial subunits from Escherichia coli, Haemophilus influenzae and Proteus mirabilis. A synthetic oligonucleotide probe, derived from the N-terminal sequence of the B. pertussis serotype 2 fimbrial subunit, was used to identify fimbrial genes in genomic Southern blots. The results suggested the presence of multiple fimbrial subunit genes in B. pertussis, B. bronchiseptica and B. parapertussis. The DNA probe was used to clone one of the three tentative fimbrial subunit genes detected in B. ...
Bordetella is a genus of small (0.2 - 0.7 µm), Gram-negative coccobacilli of the phylum Proteobacteria. Bordetella species, with the exception of B. petrii, are obligate aerobes, as well as highly fastidious, or difficult to culture. All species can infect humans. The first three species to be described (B. pertussis, B. parapertussis, B. bronchiseptica,); are sometimes referred to as the classical species. One of these (B. bronchiseptica) is also motile. B. pertussis and occasionally B. parapertussis cause pertussis or whooping cough in humans, and some B. parapertussis strains can colonise sheep. B. bronchiseptica rarely infects healthy humans, though disease in immunocompromised patients has been reported. B. bronchiseptica causes several diseases in other mammals, including kennel cough and atrophic rhinitis in dogs and pigs, respectively. Other members of the genus cause similar diseases in other mammals, and in birds (B. hinzii, B. avium). The Bordetella genus is named after Jules ...
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This vaccine offers effective, safe and effective atrophic rhinitis prevention in baby pigs. Contains avirulent live cultures of avirulent Bordetella bronchiseptica which colonize and block the adherence of disease-causing strains ...
Yes! Vaccines against parainfluenza and adenovirus type 2 (in combination with other vaccines) are routinely used as part of an adult dogs yearly checkup. Puppies are usually vaccinated for these in combination with distemper, hepatitis, and parvovirus in a series of immunizations. Specific, non-routine vaccines are also available for Bordetella bronchiseptica (another cause of canine cough). Although some veterinary practices do not use this vaccination routinely, it should be considered for pets that board, visit a daycare frequently, or for those whose veterinarian recommends it. It is important to note that the vaccines that are used to prevent this viral disease are made from only one of the over 100 different strains of the virus and therefore are not as effective against some strains as others. Some strains are not included in any vaccine; therefore, there is no prevention against them. Your veterinarian is in the best position to recommend a program of preventative health care ...
... , BRONCHI-SHIELD ORAL is a unique Canine Infectious Respiratory Disease (CIRD) vaccine because it is the first live, avirulent Bordetella bronchiseptica vaccine licensed to be administered orally to
Nobivac Intra-Trac3 ADT is for the prevention of Canine Adenovirus Type 2, Parainfluenza, Bordetella Bronchiseptica Vaccine (MLV). For INTRANASAL use in healthy dogs including pregnant females and healthy puppies.
0095] After the challenge with Bordetella bronchiseptica, general clinical observation was performed for each dog for 21 days, and its clinical symptoms were scored. The clinical scores were computed by scoring symptoms according to the following criteria every day during the observation period and adding them together. (1) Three points when body temperature (rectal temperature) is 40.0° C. or more, two points when 39.6 to 39.9° C., one point when 39.2 to 39.5° C.; (2) one point when hypodynamia is observed; (3) two points when serious anorexia is observed, one point when mild anorexia is observed; (4) one point when diarrhea is observed; (5) one point when vomiting is observed; (6) one point when dehydration is observed; (7) one point when lacrimation or eye discharge is observed in the eye; (8) three points when serious purulent nasal discharge is observed, two points when mild purulent nasal discharge is observed, one point when water-like nasal discharge is observed; (9) three points when ...
Ready to use lyophilised master mixes (8-well strips each) for detection of feline calicivirus, feline herpesvirus-1, Bordetella bronchiseptica, Chlamydophila felis, Mycoplasma felis and internal control. ...
When and how often laboratory tests are done may depend on many factors. The timing of laboratory tests may rely on the results or completion of other tests, procedures, or treatments. Lab tests may be performed immediately in an emergency, or tests may be delayed as a condition is treated or monitored. A test may be suggested or become necessary when certain signs or symptoms appear. Due to changes in the way your body naturally functions through the course of a day, lab tests may need to be performed at a certain time of day. If you have prepared for a test by changing your food or fluid intake, lab tests may be timed in accordance with those changes. Timing of tests may be based on increased and decreased levels of medications, drugs or other substances in the body. The age or gender of the person being tested may affect when and how often a lab test is required. Chronic or progressive conditions may need ongoing monitoring through the use of lab tests. Conditions that worsen and improve may ...
Pertussis toxin is coded by a multi-subunit protein complex. PCR assays focus on the promoter region of the pertussis toxin operon, which is well-characterized and is already used as a target for diagnostic PCR assays. This genetic region is not specific to B. pertussis as it can also be found in the genome of B. parapertussis and B. bronchiseptica. However, these other species contain mutations in their operon sequence, which prevent the expression of the actual toxin. These mutations provide a way to differentiate between the three species of Bordetella using melting temperatures in real-time PCR ...
The Sanger Institute has been funded by the Wellcome Trust to sequence the genomes of Bordetella pertussis strain Tohama I, B. parapertussis strain 12822 and B. bronchiseptica strain RB50 in collaboration with Duncan Maskell and Andrew Preston of the Centre for Veterinary Science, Dept. of Clinical Veterinary medicine, The University of Cambridge. The sequences and analysis are described in: Parkhill et al (2003) Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. Nature Genetics 35 32-40 (DOI: 10.1038/Ng1227), and have been submitted to EMBL/GenBank with the accession numbers: BX470248 (B. pertussis), BX470249 (B. parapertussis) and BX470250 (B. bronchiseptica). The three sequenced Bordetella strains have been deposited with the ATCC and NCTC under the following accession numbers: Bordetella parapertussis 12822: ATCC BAA-587, NCTC 13253 Bordetella bronchiseptica RB50: ATCC BAA-588, NCTC 13252 Bordetella pertussis Tohama ...
Citation: Brockmeier, S., Register, K.B. 2007. Expression of the dermonecrotic toxin by Bordetella bronchiseptica is not necessary for predisposing to infection with toxigenic Pasteurella multocida. Veterinary Microbiology. 125(3-4):284-289. Interpretive Summary: Infection with Bordetella bronchiseptica predisposes pigs to infection with Pasteurella multocida, and coinfection with these agents is often found in cases of progressive atrophic rhinitis, a disease which causes deformed growth of the pigs snout. There are several potential mechanisms by which B. bronchiseptica could predispose to infection with P. multocida. B. bronchiseptica produces a toxin called the dermonecrotic toxin, or DNT, which induces damage to swine nasal tissue and causes pneumonia and could play a role in increased colonization by P. multocida. This experiment was designed to determine whether a strain of B. bronchiseptica which does not produce DNT is still capable of predisposing pigs to infection with P. multocida. ...
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Wehmann E, Khayer B, Magyar T (2015) Heterogeneity of Bordetella bronchiseptica adenylate cyclase (cyaA) RTX domain. Arch Microbiol. 197(1): 105-112. doi: 10.1007/s00203-014-1068-x. Magyar T, Donkó T, Repa I, Kovács M (2013) Regeneration of toxigenic Pasteurella multocida induced severe turbinate atrophy in pigs detected by computed tomography. BMC Vet Res. 9: 222. doi: 10.1186/1746-6148-9-222. Sellyei B, Wehmann E, Magyar T (2012) Sequencing-independent method for the differentiation of the main phylogenetic lineages of Pasteurella multocida. J Vet Diagn Invest. 24(4): 735-738. doi: 10.1177/1040638712447794. Pósa R, Donkó T, Bogner P, Kovács M, Repa I, Magyar T (2011) Interaction of Bordetella bronchiseptica, Pasteurella multocida, and fumonisin B1 in the porcine respiratory tract as studied by computed tomography. Can J Vet Res. 75(3): 176-182.. Sellyei B, Wehmann E, Makrai L, Magyar T (2011) Evaluation of the Biolog system for the identification of certain closely related Pasteurella ...
Adenovirus 1 in canines causes respiratory infections, targets a number of organs within the physique, and causes infectious canine hepatitis (ICH), which is a illness that severely impacts the liver ... ...
Of the 10 identified species in the genus Bordetella, only four are of major medical significance. B. pertussis infects only humans and is the most important Bordetella species causing human disease. B. parapertussis causes an illness in humans that is similar to pertussis but is typically milder; co-infections with B. parapertussis and B. pertussis have been documented. With improved polymerase chain reaction (PCR) diagnostic methodology, up to 20% of patients with a pertussis-like syndrome have been found to be infected with B. holmesii, formerly thought to be an unusual cause of bacteremia. B. bronchiseptica is an important pathogen of domestic animals that causes kennel cough in dogs, atrophic rhinitis and pneumonia in pigs, and pneumonia in cats. Both respiratory infection and opportunistic infection due to B. bronchiseptica are occasionally reported in humans. B. petrii, B. hinzii, and B. ansorpii have been isolated from patients who are immunocompromised. ...
This HIPRA UNIVERSITY course was notable for the participation of experts such as Pedro Lopes, founder and managing partner of the company PMS-Serviços Veterinários, Lda, and assistant professor at the Lusófona University (Lisbon, Portugal) and Enric Marco, owner of MARCO VETGRUP S. L. and internationally renowned consultant. HIPRA was represented by local teams from each country. The sessions included the most important theoretical aspects of the disease, such as its clinical presentations, diagnosis and vaccination as the principal method of prevention, with special emphasis on both progressive and non-progressive atrophic rhinitis. It is important to emphasize the role of Bordetella bronchiseptica as the causal agent of non-progressive atrophic rhinitis, that can also act as a predisposing factor for other respiratory disorders. The sessions also included a practical session that focussed on the evaluation of the nasal turbinates for diagnosis of the disease, during which attendees could ...
VetDepot offers Bronchicine, 10 Dose Vial at the most competitive prices. Get the best deals on all your pet meds at VetDepot. Bacterin recommended for the control of Canine Infectious Tracheobronchitis (Kennel Cough) caused by Bordetella Bronchiseptica.
Looking for Bordetella? Find out information about Bordetella. A genus of gram-negative bacteria which are coccobacilli and obligate aerobes, and fail to ferment carbohydrates. These bacteria are respiratory pathogens.... Explanation of Bordetella
Definition : Molecular assay reagents intended to identify species of Bordetella, a genus of gram-negative coccobacillus bacteria, by detecting specific nucleic-acid information of the target bacteria. Some species of these bacteria may cause infections in the human respiratory tract, including whooping cough.. Entry Terms : "Whooping Cough Diagnostic Reagents" , "Pertussis Diagnostic Reagents" , "Parapertussis Diagnostic Reagents" , "Bordetella Species Detection/Identification Reagents" , "Reagents, Molecular Assay, Infection, Bacteria, Bordetella Species". UMDC code : 21449 ...
Bordetella Vaccines - Bordetella vaccines will ensure your pet doesnt come down with kennel cough. Learn more about bordetella vaccines and treatments.
The determination of the genome sequences of B. pertussis, B. parapertussis, and B. bronchiseptica was completed and the sequences were reported in 2003 by Parkhill et al. (18). We utilized early (August 2001) assemblies of these genome sequences to search for PCR target sequences that might be specific to B. pertussis. Two regions with significant sequence divergence were identified and utilized for the design of the BP283 and BP485 real-time PCR assays. Notably, the diagnostic potential of the region used for the design of our BP485 assay was also predicted previously by others using microarray-based comparative genome hybridization (4). Similarly, previous work using representational difference analysis described the genome region encompassing the BP283 target sequence as being specific to B. pertussis (15). Both assays demonstrated excellent sensitivities and specificities when applied to clinical isolates and nasopharyngeal specimens. In contrast to the IS481 assay, the BP283 and BP485 ...
Many known or suspected bacterial virulence factors require environmentally responsive control factors for expression. In Bordetella species, the BvgAS system represses and activates sets of genes, and mediates a biphasic phenotypic transition. Studies using mutants with altered signaling pathways and reversed regulatory connections have provided insights into the role of BvgAS and this phenotypic transition during the Bordetella-host interaction.
When it comes to vaccinations, many pet parents want to know exactly what their dog is being protected against. Embrace can help you out.
Though Game 1 of the ALCS saw a thrilling comeback by the New York Yankees before an eventual loss in extra-innings, the biggest story to come out of the game was that Derek Jeter would miss the rest of the postseason with a fractured ankle...
|EM>Bordetella pertussis|/EM>, |EM>Bordetella parapertussis|/EM> and |EM>Bordetella bronchiseptica|/EM> are closely related Gram-negative Beta-proteobacteria that colonizes the respiratory tracts of mammals. |EM>B. parapertussis|/EM> causes whooping cough in a wide range of animals. D-Alanine is a necessary precursor in the biosynthesis of cell [...]
Citation. Linz B, Ivanov YV, Preston A, Brinkac L, Parkhill J, Kim M, Harris SR, Goodfield LL, Fry NK, Gorringe AR, Nicholson TL, Register KB, Losada L, Harvill ET. Acquisition and Loss of Virulence-associated Factors During Genome Evolution and Speciation in Three Clades of Bordetella Species.. BMC Genomics. 2016 Sep 30; 17: 767.. External Citation. Abstract. The genus Bordetella consists of nine species that include important respiratory pathogens such as the classical species B. bronchiseptica, B. pertussis and B. parapertussis and six more distantly related and less extensively studied species. Here we analyze sequence diversity and gene content of 128 genome sequences from all nine species with focus on the evolution of virulence-associated factors.. ...
CASE SERIES SUMMARY: This case series documents five cases of pneumonia (with pleural effusion in three cases) caused by cowpox virus (CPxV) in domestic cats. Predisposition to pneumonia may have resulted from mixed infections in two cases (feline herpesvirus and Bordetella bronchiseptica in one cat, and Mycoplasma species in the other). RELEVANCE AND NOVEL INFORMATION: As well as diagnostic confirmation by previously described methods of virus isolation from skin lesions, and demonstration of pox virions in skin samples using electron microscopy and inclusion bodies in histological preparations, this is the first report of diagnosis by virus isolation from bronchoalveolar lavage fluid or pleural fluid, and demonstration of inclusion bodies in cytological preparations ...
Molecular evolution and host adaptation of Bordetella spp.: phylogenetic analysis using multilocus enzyme electrophoresis and typing with three insertion sequences ...
Bordetella are small Gram-negative coccobacilli, of which Bordetella pertussis is the most important human pathogen. It is the cause of whooping cough, which is one of the 10 leading causes of childhood death. Transmission of this highly infectious organism is primarily by aerosolized droplets.Clinical features-presentation varies with age, immunization and previous infection: (1) infants-apnoea, cyanosis, and paroxysmal cough; (2) nonimmunized children-cough, increasing in severity with distressing, repeated, forceful expirations followed by a gasping inhalation (the whoop); (3) children immunized in infancy-whooping, vomiting, sputum production; (4) adults-cough, post-tussive vomiting. Atypical mild illness is common. Complications include pneumonia, pulmonary hypertension, seizures and encephalopathy. Most deaths occur in those less than 2 months old....
... is a vaccine that helps to protect against bacterial pneumonia and kennel cough. This is the vaccine that your dog generally gets administered by drops in the nose. There is also a vaccine that can be given under the skin via injection. Ask your veterinarian which vaccine is best for your dog. ...
If you have a definite diagnosis of Bordetella, ask if they know what ABs would work best for that strain and if they dont know, I would suggest putting the other pigs on a preventative course of trimethoprim/sulfa(30-50mg/kg q12h) or baytril(5-10mg/kg q12h) - Hillyer and Quesenberry. H&Q didnt mention how long a course. Doxy might also work but it isnt mentioned in Hillyer and Quesenberry probably because at the time of print of my book, it wasnt commonly used with pigs. A drug sensitivity culture would remove the guesswork ...
Pertussis (also known as whooping cough) continues to be a global health problem with an estimated 45 million cases annually and 300,00 deaths, which occur most...
Bordetella parapertussis: | | | | |Bordetella parapertussis| | | ... World Heritage Encyclopedia, the aggregation of the largest online encyclopedias available, and the most definitive collection ever assembled.
TY - JOUR. T1 - An iron-regulated gene required for utilization of aerobactin as an exogenous siderophore in Vibrio parahaemolyticus. AU - Funahashi, Tatsuya. AU - Tanabe, Tomotaka. AU - Aso, Hiroaki. AU - Nakao, Hiroshi. AU - Fujii, Yoshio. AU - Okamoto, Keinosuke. AU - Narimatsu, Shizuo. AU - Yamamoto, Shigeo. PY - 2003/5/1. Y1 - 2003/5/1. N2 - A previous investigation using the Fur titration assay system showed that Vibrio parahaemolyticus possesses a gene encoding a protein homologous to IutA, the outer-membrane receptor for ferric aerobactin in Escherichia coli. In this study, a 5.6 kb DNA region from the V. parahaemolyticus WP1 genome was cloned and two entire genes, iutA and alcD homologues, were identified which are absent from Vibrio cholerae genomic sequences. The V. parahaemolyticus IutA and AlcD proteins share 43 % identity with the Escherichia coli IutA protein and 24 % identity with the Bordetella bronchiseptica AlcD protein of unknown function, respectively. Primer extension ...
ONE-STEP CLEANER/DISINFECTANT (EPA Reg. No. 47371-130-5741 and 47371-129-5741). Efficacy according to AOAC Use-Dilution Test modified in the presence of 5% organic soils and 400 ppm water hardness. Effective against Gram Negative pathogens: Acinetobacter calcoaceticus, Bordetella bronchiseptica, Chlamydia psittaci, Enterobacter aerogenes, Enterobacter cloacae, Escherichia coli, Fusobacterium necrophorum, Klebsiella pneumoniae, Legionella pneumophia, Pasteurella multocida, Poteus mirabilis, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella choleraesuis, Salmonella enteritidis, Salmonella typhi, Salmonella typhimurium, Serratia marcescens, Shigella flexneri, Shigella sonnei, Staphylococcus aereus (MRSA), Vancomycin Intermediate Resistant Staphylococcus aureus (VISA). Gram Positive: Listeria monocytogenes, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus faecalis, Streptococcus pyogenes, Vancomycin-resistant Enterococcus faecalis (VRE). Antibiotic Resistant bacteria: Escherichia ...
1ZBO: X-Ray Crystal Structure of Protein BPP1347 from Bordetella parapertussis. Northeast Structural Genomics Consortium Target BoR27.
The Global and Chinese Bordetella Pertussis Industry, 2011-2021 Market Research Report is a professional and in-depth study on the current state of the global Bordetella Pertussis industry with a focus on the Chinese market. The report provides key statistics on the market status of the Bordetella Pertussis manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry.. Complete report of 150 pages published in Jan 2016 is available at http://www.market-research-reports.com/434778-bordetella-pertussis-industry.. Firstly, the report provides a basic overview of the industry including its definition, applications and manufacturing technology. Then, the report explores the international and Chinese major industry players in detail. In this part, the report presents the company profile, product specifications, capacity, production value, and 2011-2016 market shares for each company. Through the statistical analysis, the report depicts the ...
BLOT kit for the detection of specific IgG antibodies to the recombinant antigens of Bordetella pertussis and Bordetella parapertussis in human serum and plasma, for automated processing using the BlueDiver Instrument.
A second focus of my laboratory is to investigate the mechanisms by which Bordetella pertussis, B. bronchiseptica, and B. avium, three gram-negative bacteria that infect the upper respiratory tract of children and domesticated animals, acquire essential nutrients required to colonize the respiratory tract and to sustain progressive infections. Iron (Fe) is one of the most important nutrients required by most, if not all infectious bacteria which must be obtained from the tissues and fluids of the infected host. Using proteomic, recombinant, immunological, and biochemical methods, we are unraveling the genetic and molecular components of these bacteria that mediate acquisition of Fe from host-derived heme, myoglobin, and hemoglobin. We have identified a cluster of genes (bhuRSTUV) which encodes five proteins required for uptake of heme and a second gene cluster (rhuIR) which encodes for two heme-dependent regulatory proteins which control heme-dependent expression of the uptake systems. Our ...
False colour transmission electron micrograph (TEM) of a thin section of the whooping cough bacteria, Bordetella pertussis. The whooping cough bacteria parasitise only humans. They cause a respiratory tract infection characterised by fits of coughing that end in loud inspiratory whoops. The infection is usually contracted in childhood and is potentially fatal in infancy. Adults are sometimes affected. The infection damages the epithelium lining the trachea and bronchi, impairing the beat of the cilia that keep the airways clean. Antibiotics are of very limited effect in treatment. Magnification: X 8800 at 35mm size. - Stock Image B220/0221
There was a report out yesterday that the cases of whooping cough (Bordetella pertussis) in Minnesota have doubled from last month and by May, have exceeded all cases reported there last year. There have been 700 cases so far this … Continue reading →. ...
Dynamics of the population structure of Bordetella pertussis as measured by IS1002-associated RFLP: comparison of pre- and post-vaccination strains and global distribution
Biohazard level, growth media and temperature, gram stain, industrial applications and more information for Bordetella pertussis.
La tos ferina es una enfermedad del tracto respiratorio que se presenta exclusivamente en los seres humanos y es causada por la bacteria gramnegativa Bordetella pertusis.
We report the repeated isolation of Bordetella petrii in the sputum of a 79-year-old female patient with diffuse bronchiectasis and persistence of the bacterium for >1 year. The patient was first hospitalized due to dyspnea, which developed into seve ...
Pinta writes, "It isnt common with pigs but it does happen, and when it does its deadly. I know of 2 outbreaks, that killed the majority of the pigs. After symptoms of Bordetella show, it progresses incredibly rapidly. Watering eyes, puffed fur, and sitting with faces in the corner of the cage are just some of the symptoms I remember being related. Some of pigs died within hours of showing illness." ...
Study Flashcards On p-hemophilus bordetella, legionella at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
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Whooping cough (pertussis) is a bacterial infection commonly found in infants. The infection spreads in the throat and the nose. This is also called as respiratory infection caused by the Bacterium, Bordetella Pertusis and mainly affects the babies younger than 6 months
That ET tube is going down the patients hatch, so disinfect it like crazy. Here are five cleaning methods going head-to-head in fighting strep and Bordetella in a new study ...
... s have been suggested as antimicrobials able to remove Bordetella bronchiseptica biofilms. The mode of killing has ... Irie Y, O'toole GA, Yuk MH (September 2005). "Pseudomonas aeruginosa rhamnolipids disperse Bordetella bronchiseptica biofilms ...
... with probiotics against Bordetella bronchiseptica in mice". The Journal of veterinary medical science / the Japanese Society of ...
These include Bordetella bronchiseptica, Streptococcus phocae, Salmonella dublin, and S. choleraesuis. Corynebacterium caspium ...
"Role of phosphoglucomutase of Bordetella bronchiseptica in lipopolysaccharide biosynthesis and virulence". Infection and ...
There are multiple causative agents, the most common being the bacterium Bordetella bronchiseptica (found in 78.7% of cases in ... respiratory infections involving Bordetella bronchiseptica can be transmissible for several weeks longer. While there was early ... "Simultaneous analysis of the nasal shedding kinetics of field and vaccine strains of Bordetella bronchiseptica". The Veterinary ... "Detection of Respiratory Viruses and Bordetella Bronchiseptica in Dogs with Acute Respiratory Tract Infections". The Veterinary ...
... from Bordetella bronchiseptica". The FASEB Journal. 25 (1 Supplement): 714.2-714.2. ISSN 0892-6638. Retrieved 13 February 2017 ...
"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica". ...
Bordetella parapertussis and Bordetella bronchiseptica". Nature Genetics. 35 (1): 32-40. doi:10.1038/ng1227. PMID 12910271. ... 2003). "Comparative analysis of the genome sequences of Bordetella pertussis, ... and Bordetella. Achtman was one of the inventors of multilocus sequence typing. His research has been funded by the ...
Bordetella parapertussis and Bordetella bronchiseptica". Nature Genetics. 35 (1): 32-40. doi:10.1038/ng1227. PMID 12910271. ... 2003). "Comparative analysis of the genome sequences of Bordetella pertussis, ...
Bordetella bronchiseptica has been identified in cats with owners that also are infected with this pathogen. Individuals having ...
Kennel cough is an infectious respiratory disease which can be caused by one of several viruses or by Bordetella bronchiseptica ...
... see Bordetella bronchiseptica). ...
The most notable of these are Bordetella bronchiseptica, one of the causes of kennel cough, Leptospira sp, which cause ... Bordetella bronchiseptica, parainfluenza virus, and canine coronavirus, should be made between an owner and a veterinarian, ...
Bordetella bronchiseptica, Candida species, Salmonella paratyphi A, and Pasteurella multocida. SBP is thought to result from a ...
Bordetella bronchiseptica Chlamydophila felis Feline calicivirus Feline viral rhinotracheitis (FVR) FHV-1 Cat-scratch disease ...
... bordetella bronchiseptica, porcine parvovirus, and Erysipelothrix rhusiopathiae among others. It is particularly important to ...
Bartonella Bartonella henselae Bartonella quintana Bordetella Bordetella bronchiseptica Bordetella pertussis Borrelia ...
Bordetella MeSH B03.660.075.027.075.024 --- Bordetella avium MeSH B03.660.075.027.075.050 --- Bordetella bronchiseptica MeSH ... Bordetella MeSH B03.440.400.425.117.075.099 --- Bordetella avium MeSH B03.440.400.425.117.075.200 --- Bordetella bronchiseptica ... B03.660.075.027.075.590 --- Bordetella parapertussis MeSH B03.660.075.027.075.600 --- Bordetella pertussis MeSH B03.660.075.027 ... MeSH B03.440.400.425.117.075.540 --- Bordetella parapertussis MeSH B03.440.400.425.117.075.550 --- Bordetella pertussis MeSH ...
Bordetella bronchiseptica-(cat kennel cough) Chlamydophila felis-(chlamydia) In South Africa the term cat flu is also used to ...
... such as Bordetella bronchiseptica, has likely increased in recent years. In some cases, most notably rabies, the parallel ...
Bordetella parapertussis and Bordetella bronchiseptica". Nature Genetics. 35 (1): 32-40. doi:10.1038/ng1227. PMID 12910271. ... and Clinical Manifestations of Respiratory Infections Due to Bordetella pertussis and Other Bordetella Subspecies". Clinical ... 1991). "Effects of Bordetella pertussis infection on human respiratory epithelium in vivo and in vitro". Infection and Immunity ... Luker, K. E.; Collier, J. L.; Kolodziej, E. W.; Marshall, G. R.; Goldman, W. E. (1993). "Bordetella pertussis Tracheal ...
Cotter P, Miller J (1997). "A mutation in the Bordetella bronchiseptica bvgS gene results in reduced virulence and increased ... The most thoroughly studied of the Bordetella species are B. bronchiseptica, B. pertussis and B. parapertussis, and the ... ISBN 0-8385-8529-9. Bauwens J, Spach D, Schacker T, Mustafa M, Bowden R (1992). "Bordetella bronchiseptica pneumonia and ... van den Akker W (1997). "Bordetella bronchiseptica has a BvgAS-controlled cytotoxic effect upon interaction with epithelial ...
Bordetella parapertussis and Bordetella bronchiseptica". Nature Genetics. 35 (1): 32-40. doi:10.1038/ng1227. PMID 12910271. " ... Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus of the genus Bordetella, and the ... 31 Bordetella". In Baron, S. Medical Microbiology (4th ed.). University of Texas Medical Branch. ISBN 0-9631172-1-1. NBK7813. " ... Unlike B. bronchiseptica, B. pertussis is not motile. Its virulence factors include pertussis toxin, filamentous hæmagglutinin ...
Both lineages are thought to have evolved from a B. bronchiseptica-like ancestor. This disease can be symptomatic or ... Bordetella parapertussis is a small Gram-negative bacterium of the genus Bordetella that is adapted to colonise the mammalian ... Wolfe D, Goebel E, Bjornstad O, Restif O, Harvil E (2007). "The O Antigen Enables Bordetella parapertussis To Avoid Bordetella ... "Clinical characteristics of illness caused by Bordetella parapertussis compared with illness caused by Bordetella pertussis". ...
B. bronchiseptica and B. avium are respiratory pathogens of other animals. B. hinzii is not pathogenic and colonizes the ... Bordetella endotoxins are unique to the genus, species, and strain. B. trematum is the only Bordetella species with a semirough ... It is unique in being oxidase negative, since all other species of Bordetella are oxidase positive. Bordetella trematum may be ... Bordetella species typically infect the respiratory tracts of humans, but B. trematum has never been isolated from a human or ...
... such as Bordetella bronchiseptica, has likely increased in recent years.[104] In some cases, most notably rabies, the parallel ...
... for Bordetella bronchiseptica (Public Health Agency of Canada) Genetic sequences of the Bordetella bronchiseptica complex ( ... Bordetella bronchiseptica is a small, Gram-negative, rod-shaped bacterium of the genus Bordetella. It can cause infectious ... J Clin Microbiol 31(7): 1838-44 "Prevention and control of Bordetella bronchiseptica infection in cats". Intervet/Schering- ... Role of canine parainfluenza virus and Bordetella bronchiseptica in kennel cough. Am J Vet Res 45(9): 1862-6. Burns, E. H., Jr ...
Bordetella bronchiseptica (Ferry 1912) Moreno-Lopez 1952. › Bordetella bronchiseptica@. › Brucella bronchiseptica. › Brucella ... Bordetella. Strains i. › 240/2. › 7865. › ATCC 31437 / Bb55. › ATCC 4617 / NCIB 9935 / NCTC 8344 / NRRL B-140, NCTC 8344. › ... "Brucella bronchiseptica" (Ferry 1912) Topley and Wilson 1929. › "Haemophilus bronchisepticus" (Ferry 1912) Wilson and Miles ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
Bordetella bronchiseptica ATCC ® 10580™ Designation: 03127 TypeStrain=False Application: Media testing Quality control strain ... Bordetella bronchiseptica (Ferry) Moreno-Lopez (ATCC® 10580™) Strain Designations: 03127 / Type Strain: no / Biosafety Level: 2 ...
Bordetella bronchiseptica ATCC ® 4617™ Designation: NRRL B-140 TypeStrain=False Application: Assay of colistimethate sodium ... Bordetella bronchiseptica (Ferry) Moreno-Lopez (ATCC® 4617™) Strain Designations: NRRL B-140 / Type Strain: no / Biosafety ...
A naturally occurring analog to phage display, the Bordetella bronchiseptica bacteriophage (BP) employs a highly variable ... Bordetella Is the Subject Area "Bordetella" applicable to this article? Yes. No. ...
Genomic DNA from Bordetella bronchiseptica strain RB50 TypeStrain=False Application: ... Bordetella bronchiseptica (Ferry) Moreno-Lopez (ATCC® BAA-588D-5™) Strain Designations: Genomic DNA from Bordetella ... Bordetella bronchiseptica (Ferry) Moreno-Lopez ATCC® BAA-588D-5™ dried Total DNA: At least 5 µg in 1X TE buffer.. OD260/OD280: ... Genomic DNA from Bordetella bronchiseptica strain RB50 [ATCC® BAA-588™] Biosafety Level 1 Biosafety classification is based on ...
Clonal diversity and host distribution in Bordetella bronchiseptica.. J M Musser, D A Bemis, H Ishikawa, R K Selander ... Clonal diversity and host distribution in Bordetella bronchiseptica. Message Subject (Your Name) has forwarded a page to you ... A total of 303 isolates of Bordetella bronchiseptica recovered from 11 host species were characterized by the electrophoretic ... The population structure of B. bronchiseptica is clonal, and its genetic diversity is limited in comparison with most other ...
... of Bordetella bronchiseptica, Gram-negative, aerobic, motile, coccobacillus prokaryote (bacterium). Bordetella bronchiseptica ... of Bordetella bronchiseptica, Gram-negative, aerobic, motile, coccobacillus prokaryote (bacterium). Bordetella bronchiseptica ... It is related to Bordetella pertussis, the obligate human pathogen, that causes pertussis or whooping cough. B. bronchiseptica ... Humans are not natural carriers of B. bronchiseptica. Magnification: x4,400 when shortest axis printed at 25 millimetres. ...
Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are closely related Gram-negative beta- ... Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.. ... B. parapertussis can also cause whooping cough, and B. bronchiseptica causes chronic respiratory infections in a wide range of ... We sequenced the genomes of B. bronchiseptica RB50 (5,338,400 bp; 5,007 predicted genes), B. parapertussis 12822 (4,773,551 bp ...
Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes.. B Aricò, R ... Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes.. B Aricò, R ... Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes.. B Aricò, R ... Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes. Message Subject ...
The proliferation of Bordetella bronchiseptica-reactive spleen cells occurred during the acute phase of infection. T cells from ... Intranasal inoculation of Bordetella bronchiseptica in mice induces long-lasting antibody and T-cell mediated immune responses. ... This observation could be due to the fact that Bordetella bronchiseptica may persist intracellularly in the host as it was ... These results suggest that Bordetella bronchiseptica infection induces primarily a Th1-type T-cell response. Importantly, the ...
B. bronchiseptica acts as a primary or secondary pathogen in feline respiratory disease. ... Nobivac Feline-Bb is for the intranasal vaccination of healthy kittens and cats for prevention of disease caused by Bordetella ... Bordetella Bronchiseptica Vaccine. Nobivac Feline-Bb is an intranasal vaccine containing an avirulent live culture of ... bronchiseptica may be the sole infectious agent in feline URI.(1) (2) Clinical signs associated with B. bronchiseptica ...
Nobivac Feline-Bb [Bordetella bronchiseptica], 25 Single Dose Vials (1010958). 5.00 stars, based on 1 reviews ...
Bordetella pertussis (strain ATCC 9797 / DSM 5571 / NCTC 10739 / 18323). Bordetella pertussis H921. Bordetella bronchiseptica ( ... Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus). Bordetella parapertussis ( ... Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251). Bordetella pertussis 2356847. Bordetella pertussis B1920. ... Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus). ,p>This subsection of the ...
Bordetella bronchiseptica derived from ATCC® 10580™*, SKU: 0655KKWIK-STIK™ 6 PackDETAILS ...
NAME: Bordetella bronchiseptica. SYNONYM OR CROSS REFERENCE: Kennel cough (dogs) Footnote 1, Haemophilus bronchiseptica ... SURVIVAL OUTSIDE HOST: Bordetella species survive only for a few hours in respiratory secretions Footnote 10. B. bronchiseptica ... Porter, J. F., & Wardlaw, A. C. (1993). Long-term survival of Bordetella bronchiseptica in lakewater and in buffered saline ... Belen, O., Campos, J. M., Cogen, P. H., & Jantausch, B. A. (2003). Postsurgical meningitis caused by Bordetella bronchiseptica ...
Of the Bordetella genus,Bordetella bronchiseptica is the principle effector of respiratory disease in a wide range of mammals ( ... Cloning and sequence of the Bordetella bronchiseptica adenylate cyclase-hemolysin-encoding gene-comparison with the Bordetella ... Characterization of the common antigenic lipopolysaccharide O-chains produced by Bordetella bronchiseptica and Bordetella ... Bordetella bronchiseptica pneumonia with shock in an immunocompetent patient.Scand. J. Infect. Dis.281996197198. ...
Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells.. C A Guzman, M Rohde, M Bock, K N ... Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells.. C A Guzman, M Rohde, M Bock, K N ... Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells.. C A Guzman, M Rohde, M Bock, K N ... Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells. Message Subject (Your Name) has ...
OBJECTIVE: The objective of this study was to determine the ability of a modified live intranasal Bordetella bronchiseptica ... DEMONSTRATION OF ONE YEAR DURATION-OF-IMMUNITY FOR A FELINE BORDETELLA BRONCHISEPTICA VACCINE ... Twenty-four vaccinated cats and 12 controls were challenged with a virulent strain of B. bronchiseptica six-months after ...
... infecting Bordetella bronchisepticawas isolated from wastewater collected at a swine farm in China. Phage vB_BbrM_PHB04 ... Yacoub AT, Katayama M, Tran J, Zadikany R, Kandula M, Greene J (2014) Bordetella bronchiseptica in the immunosuppressed ... A novel virulent bacteriophage, vB_BbrM_PHB04, infecting Bordetella bronchiseptica was isolated from wastewater collected at a ... Goodnow RA (1980) Biology of Bordetella bronchiseptica. Microbiol Res 44(4):722Google Scholar ...
Intranasal immunization of dogs against Bordetella bronchiseptica-induced tracheobronchitis (kennel cough) with modified live- ... Intranasal immunization of dogs against Bordetella bronchiseptica-induced tracheobronchitis (kennel cough) with modified live- ... Bordetella bronchiseptica vaccine Am J Vet Res. 1979 Sep;40(9):1241-3. ...
Bordetella pertussis and Bordetella bronchiseptica were both able to grow in iron-deficient medium when supplemented with iron- ... and lactoferrin-binding proteins of Bordetella pertussis and Bordetella bronchiseptica.. F D Menozzi, C Gantiez, C Locht ... and lactoferrin-binding proteins of Bordetella pertussis and Bordetella bronchiseptica. Message Subject (Your Name) has ... and lactoferrin-binding proteins of Bordetella pertussis and Bordetella bronchiseptica. ...
Bordetella bronchiseptica. URGENT! - Health Alert - Canine Cough in the Community. March 29th, 2017 - There is a strain of ... Bordetella bronchiseptica, kennel cough. Canine Infectious Respiratory Disease Complex Pet Health & Wellness - What Is Canine ... The most prevalent of the bacteria that cause this illness is Bordetella bronchiseptica. This illness involves an inflammation ... In some cases, canine cough has been seen in dogs that were current on their Bordetella vaccine, which suggests that the ...
Bordetella bronchiseptica infections are an important cause for upper tract respiratory disease (URTD) in catteries and rescue ... Bordetella bronchiseptica infection in catteries and rescue shelters. Anyone with experience of cats knows the importance of ... Recent research into respiratory diseases of cats has revealed the importance of a new bug: Bordetella bronchiseptica (more ...
  • B. bronchiseptica strains are usually resistant to streptomycin Footnote 2 , primary penicillins such as penicillin G and ampicillin Footnote 2 , miocycline Footnote 2 , erythromycin Footnote 6 , ceftriaxone Footnote 10 . (canada.ca)
  • Functional assays for PGM revealed that enzyme activity is expressed in both bvg -positive and bvg -negative strains of B. bronchiseptica and is substantially reduced in BB7865 pgm . (asm.org)
  • It has recently been stated that the LPS of some strains of B. bronchiseptica is regulated by the bvg system ( 48 ). (asm.org)
  • However, all tested B. bronchiseptica strains were able to invade dendritic cells and survive intracellularly for at least 72 h. (asm.org)
  • We describe here a side-by-side comparison of murine respiratory infection by Bordetella pertussis and Bordetella bronchiseptica strains whose genomes are currently being sequenced (Tohama I and RB50, respectively). (asm.org)
  • The Sanger Institute has completed a project to sequence further strains within the Bordetella bronchiseptica complex to investigate the evolutionary history and host tropism differences within this group of organsims. (sanger.ac.uk)
  • A novel virulent bacteriophage, vB_BbrM_PHB04, infecting Bordetella bronchiseptica was isolated from wastewater collected at a swine farm in China. (springer.com)
  • The interaction of Bordetella bronchiseptica, toxigenic Pasteurella multocida serotype D, and the mycotoxin fumonisin B(1) (FB(1)) was studied. (semanticscholar.org)
  • This study aims to monitor the prevalence of toxigenic Bordetella bronchiseptica (Bb) and Pasteurella multocida (Pm) in nursing and finishing animals by the RHINICheck test (PCR in oral fluids), and to evaluate the incidence of progressive atrophic rhinitis (PAR) in animals slaughtered at commercial meatpacking units. (hipra.com)
  • In addition, polymerase chain reaction-based detection of phage genes in phage-resistant B. bronchiseptica variants revealed no evidence of lysogenic activity of phage vB_BbrM_PHB04. (springer.com)
  • Detection of genes expressed in Bordetella bronchiseptica colonizing rat trachea by in vivo expressed-tag immunoprecipitation method. (nih.gov)
  • B. bronchiseptica is of worldwide prevalence as it is a commensal organism of the respiratory tract in humans Footnote 4 . (canada.ca)
  • 8. The pharmaceutical composition of claim 4 , wherein the cupredoxin peptide is from an organism selected from the group consisting of Pseudomonas aeruginosa, Alcaligenes faecalis, Achromobacter xylosoxidan, Bordetella bronchiseptica, Methylomonas sp. (google.com)
  • Bordetella trematum is a nonpathogenic, opportunistic organism whose sole source of isolation is open, human wounds. (wikipedia.org)
  • This observation could be due to the fact that Bordetella bronchiseptica may persist intracellularly in the host as it was demonstrated in vitro. (nih.gov)
  • B. bronchiseptica , which was highly resistant to naive serum in vitro, caused bacteremia in these immunodeficient mice, while B. pertussis , which was highly sensitive to naive serum, did not cause bacteremia. (asm.org)
  • B. bronchiseptica was, however, killed by immune serum in vitro, and adoptive transfer of anti- Bordetella antibodies protected SCID-beige mice from B. bronchiseptica lethal infection. (asm.org)
  • B. bronchiseptica was dramatically more active than B. pertussis in mediating the lysis of J774 cells in vitro and in inducing apoptosis of inflammatory cells in mouse lungs. (asm.org)
  • In this report, we determine that Bordetella bronchiseptica can form biofilms in vitro and that the generation of biofilm is maximal in the Bvgi phase. (mendeley.com)
  • The phosphoglucomutase (PGM)-encoding gene of Bordetella bronchiseptica is required for lipopolysaccharide (LPS) biosynthesis. (asm.org)
  • 7 Injectable Bordetella vaccines also have a longer onset to protection since they require two doses separated by a few weeks to initiate immunity. (bmj.com)
  • The alcA gene, essential for the production of the dihydroxamate siderophore, alcaligin, by Bordetella bronchiseptica, was cloned and sequenced. (nih.gov)
  • Here we investigate the role of one such gene, sigE, in stress survival and pathogenesis of Bordetella bronchiseptica . (biomedcentral.com)
  • Several studies, some comparative, have evaluated the efficacy of these vaccines against B bronchiseptica challenge with varying results. (bmj.com)
  • Growth of the organisms under modulating conditions showed that the production of these IRPs is not under the genetic transcriptional control of vir or bvg, the general virulence regulon in Bordetella spp. (asm.org)