A species of BORDETELLA that is parasitic and pathogenic. It is found in the respiratory tract of domestic and wild mammalian animals and can be transmitted from animals to man. It is a common cause of bronchopneumonia in lower animals.
A genus of gram-negative, aerobic bacteria whose cells are minute coccobacilli. It consists of both parasitic and pathogenic species.
Infections with bacteria of the genus BORDETELLA.
A species of gram-negative, aerobic bacteria that is the causative agent of WHOOPING COUGH. Its cells are minute coccobacilli that are surrounded by a slime sheath.
A chronic inflammation in which the NASAL MUCOSA gradually changes from a functional to a non-functional lining without mucociliary clearance. It is often accompanied by degradation of the bony TURBINATES, and the foul-smelling mucus which forms a greenish crust (ozena).
A species of BORDETELLA with similar morphology to BORDETELLA PERTUSSIS, but growth is more rapid. It is found only in the RESPIRATORY TRACT of humans.
A set of BACTERIAL ADHESINS and TOXINS, BIOLOGICAL produced by BORDETELLA organisms that determine the pathogenesis of BORDETELLA INFECTIONS, such as WHOOPING COUGH. They include filamentous hemagglutinin; FIMBRIAE PROTEINS; pertactin; PERTUSSIS TOXIN; ADENYLATE CYCLASE TOXIN; dermonecrotic toxin; tracheal cytotoxin; Bordetella LIPOPOLYSACCHARIDES; and tracheal colonization factor.
The scroll-like bony plates with curved margins on the lateral wall of the NASAL CAVITY. Turbinates, also called nasal concha, increase the surface area of nasal cavity thus providing a mechanism for rapid warming and humidification of air as it passes to the lung.
A suspension of killed Bordetella pertussis organisms, used for immunization against pertussis (WHOOPING COUGH). It is generally used in a mixture with diphtheria and tetanus toxoids (DTP). There is an acellular pertussis vaccine prepared from the purified antigenic components of Bordetella pertussis, which causes fewer adverse reactions than whole-cell vaccine and, like the whole-cell vaccine, is generally used in a mixture with diphtheria and tetanus toxoids. (From Dorland, 28th ed)
Diseases of domestic swine and of the wild boar of the genus Sus.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria normally found in the flora of the mouth and respiratory tract of animals and birds. It causes shipping fever (see PASTEURELLOSIS, PNEUMONIC); HEMORRHAGIC BACTEREMIA; and intestinal disease in animals. In humans, disease usually arises from a wound infection following a bite or scratch from domesticated animals.
Low-molecular-weight compounds produced by microorganisms that aid in the transport and sequestration of ferric iron. (The Encyclopedia of Molecular Biology, 1994)
Agents that cause agglutination of red blood cells. They include antibodies, blood group antigens, lectins, autoimmune factors, bacterial, viral, or parasitic blood agglutinins, etc.
The proximal portion of the respiratory passages on either side of the NASAL SEPTUM. Nasal cavities, extending from the nares to the NASOPHARYNX, are lined with ciliated NASAL MUCOSA.
Infections with bacteria of the genus PASTEURELLA.
Specific substances elaborated by plants, microorganisms or animals that cause damage to the skin; they may be proteins or other specific factors or substances; constituents of spider, jellyfish or other venoms cause dermonecrosis and certain bacteria synthesize dermolytic agents.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Proteins isolated from the outer membrane of Gram-negative bacteria.
Proteins found in any species of bacterium.
A species of BORDETELLA isolated from the respiratory tracts of TURKEYS and other BIRDS. It causes a highly contagious bordetellosis.
Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.
One of the virulence factors produced by virulent BORDETELLA organisms. It is a bifunctional protein with both ADENYLYL CYCLASES and hemolysin components.
Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.
The oldest recognized genus of the family PASTEURELLACEAE. It consists of several species. Its organisms occur most frequently as coccobacillus or rod-shaped and are gram-negative, nonmotile, facultative anaerobes. Species of this genus are found in both animals and humans.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.
Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.
One of the virulence factors produced by BORDETELLA PERTUSSIS. It is a multimeric protein composed of five subunits S1 - S5. S1 contains mono ADPribose transferase activity.
The cartilaginous and membranous tube descending from the larynx and branching into the right and left main bronchi.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
The aggregation of ERYTHROCYTES by AGGLUTININS, including antibodies, lectins, and viral proteins (HEMAGGLUTINATION, VIRAL).
The functional hereditary units of BACTERIA.
A respiratory infection caused by BORDETELLA PERTUSSIS and characterized by paroxysmal coughing ending in a prolonged crowing intake of breath.
Suspensions of attenuated or killed bacteria administered for the prevention or treatment of infectious bacterial disease.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The tubular and cavernous organs and structures, by means of which pulmonary ventilation and gas exchange between ambient air and the blood are brought about.
Thin, hairlike appendages, 1 to 20 microns in length and often occurring in large numbers, present on the cells of gram-negative bacteria, particularly Enterobacteriaceae and Neisseria. Unlike flagella, they do not possess motility, but being protein (pilin) in nature, they possess antigenic and hemagglutinating properties. They are of medical importance because some fimbriae mediate the attachment of bacteria to cells via adhesins (ADHESINS, BACTERIAL). Bacterial fimbriae refer to common pili, to be distinguished from the preferred use of "pili", which is confined to sex pili (PILI, SEX).
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
A class of weak acids with the general formula R-CONHOH.
A genus of gram-negative, aerobic, motile bacteria that occur in water and soil. Some are common inhabitants of the intestinal tract of vertebrates. These bacteria occasionally cause opportunistic infections in humans.
It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)
Further or repeated use of equipment, instruments, devices, or materials. It includes additional use regardless of the original intent of the producer as to disposability or durability. It does not include the repeated use of fluids or solutions.
A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)
A mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Information or data used to ensure the safe handling and disposal of substances in the workplace. Such information includes physical properties (i.e. melting, boiling, flashing points), as well as data on toxicity, health effects, reactivity, storage, disposal, first-aid, protective equipment, and spill-handling procedures.
Elements, compounds, mixtures, or solutions that are considered severely harmful to human health and the environment. They include substances that are toxic, corrosive, flammable, or explosive.

Probing the function of Bordetella bronchiseptica adenylate cyclase toxin by manipulating host immunity. (1/244)

We have examined the role of adenylate cyclase-hemolysin (CyaA) by constructing an in-frame deletion in the Bordetella bronchiseptica cyaA structural gene and comparing wild-type and cyaA deletion strains in natural host infection models. Both the wild-type strain RB50 and its adenylate cyclase toxin deletion (DeltacyaA) derivative efficiently establish persistent infections in rabbits, rats, and mice following low-dose inoculation. In contrast, an inoculation protocol that seeds the lower respiratory tract revealed significant differences in bacterial numbers and in polymorphonuclear neutrophil recruitment in the lungs from days 5 to 12 postinoculation. We next explored the effects of disarming specific aspects of the immune system on the relative phenotypes of wild-type and DeltacyaA bacteria. SCID, SCID-beige, or RAG-1(-/-) mice succumbed to lethal systemic infection following high- or low-dose intranasal inoculation with the wild-type strain but not the DeltacyaA mutant. Mice rendered neutropenic by treatment with cyclophosphamide or by knockout mutation in the granulocyte colony-stimulating factor locus were highly susceptible to lethal infection by either wild-type or DeltacyaA strains. These results reveal the significant role played by neutrophils early in B. bronchiseptica infection and by acquired immunity at later time points and suggest that phagocytic cells are a primary in vivo target of the Bordetella adenylate cyclase toxin.  (+info)

Genetic basis for lipopolysaccharide O-antigen biosynthesis in bordetellae. (2/244)

Bordetella bronchiseptica and Bordetella parapertussis express a surface polysaccharide, attached to a lipopolysaccharide, which has been called O antigen. This structure is absent from Bordetella pertussis. We report the identification of a large genetic locus in B. bronchiseptica and B. parapertussis that is required for O-antigen biosynthesis. The locus is replaced by an insertion sequence in B. pertussis, explaining the lack of O-antigen biosynthesis in this species. The DNA sequence of the B. bronchiseptica locus has been determined and the presence of 21 open reading frames has been revealed. We have ascribed putative functions to many of these open reading frames based on database searches. Mutations in the locus in B. bronchiseptica and B. parapertussis prevent O-antigen biosynthesis and provide tools for the study of the role of O antigen in infections caused by these bacteria.  (+info)

Bordetella bronchiseptica infection in human immunodeficiency virus-infected patients. (3/244)

Bordetella bronchiseptica is a pleomorphic gram-negative coccobacillus that commonly causes respiratory tract infections in dogs. We identified nine human immunodeficiency virus (HIV)-infected persons with culture-confirmed B. bronchiseptica infections (eight respiratory tract and one disseminated infection). The respiratory illnesses ranged in severity from mild upper respiratory tract infection to pneumonia. All nine patients had had at least one AIDS-defining condition before the B. bronchiseptica infection. Two patients had household contact with dogs before their illnesses, and one had household contact with cats. Infection due to B. bronchiseptica is uncommon in HIV-infected persons. Additional data are needed to fully define the spectrum of disease due to B. bronchiseptica infections and to evaluate the possibility that this infection may be acquired from pets. Treatment of B. bronchiseptica infection should be tailored to the patient and should be based on the results of susceptibility testing.  (+info)

Essential role of the iron-regulated outer membrane receptor FauA in alcaligin siderophore-mediated iron uptake in Bordetella species. (4/244)

Phenotypic analysis using heterologous host systems localized putative Bordetella pertussis ferric alcaligin transport genes and Fur-binding sequences to a 3.8-kb genetic region downstream from the alcR regulator gene. Nucleotide sequencing identified a TonB-dependent receptor family homolog gene, fauA, predicted to encode a polypeptide with high amino acid sequence similarity with known bacterial ferric siderophore receptors. In Escherichia coli, the fauA genes of both B. pertussis and Bordetella bronchiseptica directed the production of a 79-kDa polypeptide, approximating the predicted size of the mature FauA protein. B. bronchiseptica fauA insertion mutant BRM17 was unable to utilize ferric alcaligin, and in complementation analyses ferric alcaligin utilization was restored to this mutant by supplying the wild-type fauA gene in trans. Mutant BRM18, carrying a nonpolar in-frame fauA deletion mutation, was defective in ferric alcaligin utilization and (55)Fe-ferric alcaligin uptake and no longer produced a 79-kDa iron-regulated outer membrane protein. In complementation analyses, BRM18 merodiploids bearing the wild-type fauA gene in trans regained ferric alcaligin siderophore transport and utilization functions and produced the 79-kDa protein. Analysis of a plasmid-borne fauA-lacZ operon fusion confirmed that fauA is subject to iron regulation at the transcriptional level and that cis-acting transcriptional control elements mediating fauA iron repressibility reside within the 3.8-kb PstI fauA DNA region. Moreover, expression of the fauA-lacZ fusion gene under iron starvation conditions was shown to be alcR dependent. FauA is a 79-kDa iron-regulated outer membrane receptor protein required for transport and utilization of ferric alcaligin siderophore complexes by Bordetella species.  (+info)

Disruption of tonB in Bordetella bronchiseptica and Bordetella pertussis prevents utilization of ferric siderophores, haemin and haemoglobin as iron sources. (5/244)

The Bordetella bronchiseptica tonB gene was cloned by detection of a chromosomal restriction fragment hybridizing with each of two degenerate oligonucleotides that corresponded to Pro-Glu and Pro-Lys repeats characteristic of known TonB proteins. The tonB(Bb) gene was situated upstream of exbB and exbD homologues and downstream of a putative Fur-regulated promoter. Hybridization results indicated that the tonB operon and flanking regions were highly conserved between B. bronchiseptica, Bordetella pertussis and Bordetella parapertussis. Disruption of tonB in B. bronchiseptica resulted in inability to grow in iron-limiting media, and inability to utilize alcaligin, enterobactin, ferrichrome, desferroxamine B, haemin and haemoglobin. Although it was not possible to inactivate tonB in a clinical B. pertussis isolate, tonB was disrupted in a laboratory B. pertussis strain previously selected for the ability to grow on Luria-Bertani medium. This B. pertussis tonB mutant shared a similar iron complex utilization deficient phenotype with the B. bronchiseptica tonB mutant. The B. bronchiseptica tonB operon present on a plasmid did not complement an Escherichia coli tonB mutant, but inefficient reconstitution of enterobactin utilization was observed in one fepA mutant harbouring plasmid copies of the B. pertussis fepA homologue and tonB(Bb) operon.  (+info)

Bordetella bronchiseptica-mediated cytotoxicity to macrophages is dependent on bvg-regulated factors, including pertactin. (6/244)

The effect of Bordetella bronchiseptica infection on the viability of murine macrophage-like cells and on primary porcine alveolar macrophages was investigated. The bacterium was shown to be cytotoxic for both cell types, particularly where tight cell-to-cell contacts were established. In addition, bvg mutants were poorly cytotoxic for the eukaryotic cells, while a prn mutant was significantly less toxic than wild-type bacteria. B. bronchiseptica-mediated cytotoxicity was inhibited in the presence of cytochalasin D or cycloheximide, an inhibitor of microfilament-dependent phagocytosis or de novo eukaryotic protein synthesis, respectively. The mechanism of eukaryotic cell death was examined, and cell death was found to occur primarily through a necrotic pathway, although a small proportion of the population underwent apoptosis.  (+info)

Pregenomic comparative analysis between bordetella bronchiseptica RB50 and Bordetella pertussis tohama I in murine models of respiratory tract infection. (7/244)

We describe here a side-by-side comparison of murine respiratory infection by Bordetella pertussis and Bordetella bronchiseptica strains whose genomes are currently being sequenced (Tohama I and RB50, respectively). B. pertussis and B. bronchiseptica are most appropriately classified as subspecies. Their high degree of genotypic and phenotypic relatedness facilitates comparative studies of pathogenesis. RB50 and Tohama I differ in their abilities to grow in the nose, trachea, and lungs of BALB/c mice and to induce apoptosis, lung pathology, and an antibody response. To focus on the interactions between the bacteria and particular aspects of the host immune response, we used mice with specific immune defects. Mice lacking B cells and T cells were highly susceptible to B. bronchiseptica and were killed by intranasal inoculation with doses as low as 500 CFU. These mice were not killed by B. pertussis, even when doses as high as 10(5) CFU were delivered to the lungs. B. bronchiseptica, which was highly resistant to naive serum in vitro, caused bacteremia in these immunodeficient mice, while B. pertussis, which was highly sensitive to naive serum, did not cause bacteremia. B. bronchiseptica was, however, killed by immune serum in vitro, and adoptive transfer of anti-Bordetella antibodies protected SCID-beige mice from B. bronchiseptica lethal infection. Neutropenic mice were similarly killed by B. bronchiseptica but not B. pertussis infection, suggesting neutrophils are critical to the early inflammatory response to the former but not the latter. B. bronchiseptica was dramatically more active than B. pertussis in mediating the lysis of J774 cells in vitro and in inducing apoptosis of inflammatory cells in mouse lungs. This side-by-side comparison describes phenotypic differences that may be correlated with genetic differences in the comparative analysis of the genomes of these two highly related organisms.  (+info)

Polymorphism in the pertussis toxin promoter region affecting the DNA-based diagnosis of Bordetella infection. (8/244)

The pertussis toxin (PT) promoter region is a frequently used target for DNA-based diagnosis of pertussis and parapertussis infections. The reported polymorphism in this region has also allowed discrimination of species in mixtures with several Bordetella species by their specific PCR amplicon restriction patterns. In the present study, we investigated the degree of polymorphism in order to confirm the reliability of the assay. Five different sequence types of the amplified 239- or 249-bp region were found among the 33 Bordetella pertussis, B. parapertussis, and B. bronchiseptica American Type Culture Collection reference strains and patient isolates analyzed. According to the sequences that were obtained and according to the PT promoter sequences already available in the databases, restriction enzyme analysis with TaqI, BglI, and HaeII, which gave four different patterns, can be performed to reliably identify B. pertussis, B. parapertussis, and B. bronchiseptica.  (+info)

Adler K, Radeloff I, Stephan B, Greife H, Helelmann K. Bacteriological and virological status in upper respiratory tract infections of cats. Berl.Munch.Tierarztl.Wochenschr. 2007;120 (3-4):120-125.. Veir JK, Ruch-Gallie R, Spindel ME, Lappin MR. Prevalence of selected infectious organisms and comparisons of two anatomic sampling sites in shelter cats with upper respiratory tract diseases. J.Feline Med. Surg. 2008;10(6):551-557.. Schwarz S, Alesik E, Grobbel M, Lübke-Becker A, Werckenthin C, Wieler LH, et al. Antimicrobial susceptibility of Pasteurella multocida and Bordetella bronchiseptica from dogs and cats as determined in the BfT-GermVet monitoring program 2004-2006. Berl. Munch.Tierarztl.Wochenschr. 2007;120(9-10): 423-430.. Bauwens JE, Spach DH, Schacker TW, Mustafa MM, Bowden RA. Bordetella bronchiseptica pneumonia and bacteremia following bone marrow transplantation. J Clin Microbiol 1992;30: 2474-5.. Binns SH, Dawson S, Speakman AJ, et al. Prevalence and risk factors or feline ...
Bordetella bronchiseptica ATCC ® BAA-588D-5™ Designation: Genomic DNA from Bordetella bronchiseptica strain RB50 TypeStrain=False Application:
Coloured scanning electron micrograph (SEM) of Bordetella bronchiseptica, Gram-negative, aerobic, motile, coccobacillus prokaryote (bacterium). Bordetella bronchiseptica typically infects the respiratory tracts of smaller mammals (cats, dogs, rabbits). It causes infectious bronchitis, but rarely infects humans. It does not express pertussis toxin, which is one of the characteristic virulence factors of B. pertussis. It is related to Bordetella pertussis, the obligate human pathogen, that causes pertussis or whooping cough. B. bronchiseptica does not express pertussis toxin, which is one of the characteristic virulence factors of B. pertussis. Humans are not natural carriers of B. bronchiseptica. Magnification: x4,400 when shortest axis printed at 25 millimetres. - Stock Image C032/2756
TY - JOUR. T1 - Clinical and pathological effects of the dermonecrotic toxin of Bordetella bronchiseptica and Pasteurella multocida in specific-pathogen-free piglets.. AU - Eliás, B.. AU - Boros, G.. AU - Albert, M.. AU - Tuboly, S.. AU - Gergely, P.. AU - Papp, L.. AU - Barna Vetró, I.. AU - Rafai, P.. AU - Molnár, E.. PY - 1990/8. Y1 - 1990/8. N2 - The role of dermonecrotic toxin (DNT) of Bordetella bronchiseptica and Pasteurella multocida, purified by repeated chromatography in Sephacryl S-200 gel, in the pathogenesis of atrophic rhinitis (AR) of swine was studied bacteriologically, clinically and pathologically. Two-week-old specific pathogen-free (SPF) piglets were parenterally treated with 30 micrograms of DNT 3 times at 2-day interval and 7-week-old piglets were treated with 15 micrograms of DNT twice a week for 5 weeks. In 2- to 3-week-old piglets, both B. bronchiseptica DNT and P. multocida DNT produced nasal turbinate lesions with similar severity, characterized by damage of the ...
DEMONSTRATION OF ONE YEAR DURATION-OF-IMMUNITY FOR A FELINE BORDETELLA BRONCHISEPTICA VACCINE. J.R. Williams, R. Laris. OBJECTIVE: The objective of this study was to determine the ability of a modified live intranasal Bordetella bronchiseptica vaccine (Nobivac-Bb) to prevent disease in cats for a period of one year following vaccination. EXPERIMENTAL DESIGN: Forty-eight cats were vaccinated according to manufacturers instructions. Twenty-four vaccinated cats and 12 controls were challenged with a virulent strain of B. bronchiseptica six-months after vaccination, and two additional groups of vaccinates and controls were challenged one year after vaccination. Clinical signs were recorded daily for two weeks after challenge, and clinical scores were calculated for each group. The Mann-Whitney U test was used to determine if clinical scores in the vaccinated groups were significantly different from scores in the control groups. RESULTS: The mean clinical score for vaccinated cats at six-months ...
Members of the Bordetella genus alternate between two distinct phenotypic phases in response to changes in their environment. This switch, termed phenotypic modulation, is mediated by the BvgAS sensory transduction system. We developed an animal model based on the interaction of Bordetella bronchiseptica with one of its natural hosts, the rabbit. To investigate the importance of BvgAS signal transduction, we constructed constitutive (RB53) and Bvg- (RB54) phase-locked derivatives of a wild-type strain, RB50. RB50 and RB53, but not RB54, established respiratory infections in B. bronchiseptica-free rabbits with an intranasal 50% infective dose of less than 200 organisms, and the course of the infection closely resembled that observed with naturally infected rabbits. Bacteria were recovered from the nasal cavity, larynx, trachea, and lungs in similar numbers from RB50- and RB53-infected rabbits, yet no pathology was detected by histological examination of lung and tracheal sections. The antibody ...
Nobivac Feline-Bb is for the intranasal vaccination of healthy kittens and cats for prevention of disease caused by Bordetella bronchiseptica. B. bronchiseptica acts as a primary or secondary pathogen in feline respiratory disease.
Twelve specific pathogen-free (SPF) puppies were vaccinated intranasally with a bivalent, modified live vaccine against infectious tracheobronchitis (group 1) and six puppies of the same age and from the same source served as unvaccinated controls (group 2). Both groups were challenged with wild-type Bordetella bronchiseptica and canine parainfluenza virus by the aerosol route 56 weeks after group 1 had been vaccinated, and at the same time six 10-week-old SPF puppies from the same source (group 3) were also challenged. Oronasal swabs were taken regularly before and after the challenge, for the isolation of bacteria and viruses, and the dogs were observed for clinical signs for three weeks after the challenge. The control dogs became culture-positive for B bronchiseptica and canine parainfluenza virus, but the isolation yields from the vaccinated group were significantly lower (P,0·05). The mean clinical scores of the vaccinated group were 61 per cent lower than the scores of group 2 ...
Bordetella bronchiseptica ATCC ® 10580™ Designation: 03127 TypeStrain=False Application: Media testing Quality control strain Quality control strain for BBL and bioMérieux Vitek products Food testing
5] Binns, S. H., Corkill, J. E., Dawson, S., Gaskell, R. M., Hart, C. A., Kariuki, S., Osborn, A. M., Saunders, J. R., and Speakman, A. J. 1997. Characterization of antibiotic resistance plasmids from Bordetella bronchiseptica. Journal of Antimicrobial Chemotherapy. 40: 811-816. [[6] Appel J. G. M., Bemis, A. D., and Greisen, A. H. 1977. Pathogenesis of canine bordetellosis. The Journal of Infectious Diseases. 135: 753-762. [[7] Vanderzee, A, Mooi, F., Emben, J. V., and Musser, J. Molecular evolution and host adaptation of Bordetella spp.: phylogenetic analysis using multilocus enzyme electrophoresis and typing with three insertion sequences. 1997. Journal of Bacteriology. 179: 6609-6617. [[8] Roberts, M., and Stevenson, A. 2003. Use of Bordetella bronchiseptica and Bordetella pertussis as live vaccines and vectors for heterologous antigens. FEMS Immunology and Medical Microbiology. 37: 121-128. [[9] Arico, B. and Rappuoli, R. Bordetella parapertussis and Bordetella ...
Both virus and bacterial causes of kennel cough are spread through the air by infected dogs sneezing and coughing. It can also spread through contact with contaminated surfaces and through direct contact. It is highly contagious, even days or weeks after symptoms disappear. Symptoms begin usually two to three days after exposure,[2] and can progress to pneumonia. Various studies have shown that kennel cough is a zoonotic disease, meaning it can transfer from animal to human and vice versa. These studies indicate that Bordetella bronchiseptica infections in humans are uncommon and generally occur in immunocompromised individuals ...
Dr. Burns conducts undergraduate research in the area of microbiology. Students in his lab has performed projects studying interaction of Bordetella bronchiseptica with animal cells, prevalence of Bordetella species in the wild animal population, host specificity of Bordetella bronchiseptica, matrix metalloprotease activation by Group A Streptococcus, coliforms in the Olentangy River Wetlands Research Park, and carriage of Streptococcus pyogenes among Shawnee State University students. Undergraduate students have presented their research at the American Society for Microbiology general meeting, the Ohio Academy of Sciences Annual Meeting, the Beta Beta Beta Biological Honor Society District Convention, and the Celebration of Scholarship Undergraduate Conference, supported by funds from the Department of Natural Sciences, the CAS Deans Office, and the Board of Trustees Award. ...
Replied on 04/19/2011 If she hasnt been vaccinated within the past 6 months she may not be protected as immunity wanes quickly with this particular vaccine. Even if she has been vaccinated recently Bordetella Bronchiseptica is a bacterium that is only part of the complex of pathogens that can cause Kennel Cough . Other components can include Adenovirus, Parainfluenza virus , Mycoplasma and occasionally Herpes virus. The most common cause of Kennel Cough is a combination of Parainfluenza virus and Bordetella Bronchiseptica . We vaccinate against the most common strains of Bordetella and the Parainfluenza virus but there are many variants of Bordetella and we cant vaccinate against them all. The good news is that because she was vaccinated some immunity memory is present and she probably wont get as sick as she would have without the vaccine. Keep her as quiet as possible as exercise worsens the cough. Watch her for lethargy, lack of appetite or a cough that interferes with her sleeping. If ...
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Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
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A syndrome reported in the USA and Europe, typically affecting multiple cats in a group,3 but individual cats too.4 Associated with high mortality (30-50%), interestingly especially in adult cats. Clinical signs include facial and paw cutaneous oedema and ulceration, bruising, pyrexia, icterus and cat flu signs.. Chlamydophila felis. C. felis is a common cause of conjunctivitis, especially in young (, 1 year of age) cats.5 Conjunctivitis, ocular discharge (initially serous and unilateral, then mucopurulent and bilateral) and chemosis are seen, but corneal ulceration is not a feature. Occasionally may see sneezing and a nasal discharge too.. Mycoplasma spp. and Bordetella bronchiseptica. Both Mycoplasma spp. and B. bronchiseptica can be found in normal cats, but have also been associated with disease. Mycoplasma spp. can cause conjunctivitis, and an association with URTD has been reported,6 whilst B. bronchiseptica can cause ocular and nasal discharge, sneezing, pyrexia ± coughing.7. Carrier ...
Eight collie-cross pups, eight weeks old, were inoculated intramuscularly with an aluminum hydroxide adjuvanted preparation of killed Bordetella bronchiseptica; the inoculation was repeated after two weeks. Two weeks after the second inoculation, the vaccinated dogs and a control group of four unvaccinated animals were placed in contact with a group of five pups of similar age which had been experimentally infected with a pathogenic strain of B bronchiseptica by an aerosol method. All four unvaccinated control dogs as well as all five experimentally infected dogs developed a respiratory disease characterised by persistent coughing. Six of the vaccinated dogs remained free from clinical respiratory disease while disease was less severe and of shorter duration in the remaining two than in controls. Only slight changes were found in the lungs of vaccinated animals at necropsy while in the controls there was a severe tracheobronchitis. There was a marked reduction in the numbers of B bronchiseptica ...
Bordetella pertussis (whooping cough) - no known animal or environmental reservoir (Mattoo and Cherry 2005 - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1082800/ ). Bordetella bronchiseptica, B. parapertussis, and B. holmesii are associated with respiratory infections in humans and other mammals - B. bronchiseptica is a major cause of kennel cough in dogs (Mattoo and Cherry 2005 - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1082800/ ). Polio can infect primates: http://jid.oxfordjournals.org/content/175/Supplement_1/S286.full.pdf. Measles: no animal or environmental reservoir is known to exist however Many primate species are susceptible to measles virus infection http://jid.oxfordjournals.org/content/204/suppl_1/S47.full.pdf+html. Cholera: aquatic plants, animals, and sediments (zzoplankton largest known) http://onlinelibrary.wiley.com/doi/10.1111/j.1758-2229.2009.00128.x/abstract. Humans are the only natural reservoir for N. ...
Cavitary Pneumonia in an AIDS Patient Caused by an Unusual Bordetella bronchiseptica Variant Producing Reduced Amounts of Pertactin and Other Major Antigens: Al
An inner ear infection may have started with an outer ear infection, which remained unnoticed and untreated and gradually worked its way into the inner ear, or with a middle ear infection, which resulted from an upper respiratory infection. Or it may have arisen from bacteria in the nasal cavity or bloodstream. A radiograph of the head may help determine if the middle ears are affected. Some of the bacteria which have been cultured from ear infections are Staphylococcus sp, Pseudomonas aeruginosa, Pasteurella multocida, Bordetella bronchiseptica, Proteus mirabilis, Streptoccus epidermidis, Bacteroides spp. and Escherichia coli.. Treatment needs to be aggressive and prolonged. If exudate (pus) is found deep in the ear canal, a culture and sensitivity should be done in order to determine the bacterial agent and which antibiotics will be most effective in eliminating the infection. However, if it is impossible to access the bacteria in order to do the culture, many veterinarians will opt to treat ...
This study demonstrates that pig Oral Fluid may contain genetic material of Bordetella bronchiseptica (Bb) and Pasteurella multocida (PMT), which is detectable by qPCR. The detection rate was similar in OF and NS from the same animal or group of animals. These results suggest that OF could be used for monitoring of AR in pigs, reducing labor and animal stress during sample collection, and providing valuable information about the health status of breeding and growing pigs in regards to AR. The findings also suggest that there may be a significant proportion of pigs free from Bb infection, although it is considered a normal inhabitant of the respiratory tract in pigs. ...
Jangkitan bermula dari luar telinga dan terus ke dalam telinga. Atau terdapat bakteria didalam mulut atau salur darah. Dengan menggunakan radiograph dibahagian kepala ia akan dapat dikenalpasti. Beberapa bakteria tersebut ialah Staphylococcus sp, Pseudomonas aeruginosa, Pasteurella multocida, Bordetella bronchiseptica, Proteus mirabilis, Streptococcus epidermidis, Bacteroides spp. and Escherichia Coli. ...
The API 20E system for Enterobacteriaceae, recently broadened to include identification of nonfermentative gram-negative bacteria, was evaluated and compared with the conventional method for complete identification of 221 nonfermenters, which were well distributed into 48 species or biotypes and included organisms not listed in the API 20E data base. The results of 16 tests common to both systems were in close agreement. The API 20E system correctly identified 71 (43%) of the 165 organisms included in the API 20E data base. However, almost 90% of Acinetobacter calcoaceticus, three species of Pseudomonas, and Bordetella bronchiseptica were correctly identified to species. ...
Many 5 or 7-way vaccines that vets will often recommend for puppies can help prevent parainfluenza and other infections that tend to complicate kennel cough infections and bring on more severe symptoms. A vaccine against both parainfluenza and Bordetella bronchiseptica can also be given to puppies to provide a large amount of protection against kennel cough. Side effects of this vaccine can include the appearance of symptoms similar to kennel cough which clear up within a few days, often without treatment. The parainfluenza virus can be spread to other pets for up to 3 or 4 days after vaccination, so keeps your dog isolated from other dogs after the vaccine is administered. ...
Treatment is seldom required. Similarly, bacteria like the Bordetella bronchiseptica and Chlamydophila felis can cause respiratory issues in cats.Watch for a runny nose, congestion, wheezing and lethargy. The FVRCP vaccine is vital since it protects against three feline viruses: rhinotracheitis, calicivirus, and panleukopenia (more commonly known as distemper). FCV most severely affects kittens and debilitated cats, but overall death loss is generally low. The chlamydial vaccines are available in combination with FVR-FCV and panleukopenia vaccines. Rhinotracheitis, caused by the feline herpes virus, is a common virus that invades the nose lining, sinuses, throat, windpipe and eye membranes. false positive. The vaccine may cause side effects such as lack of appetite and may feel tired, may run a fever for 24 hours after vaccination, and may not eat as well. Fortunately, we can vaccinate against cat flu. Just as in humans, sneezing in cats is an explosive release of air through the nose and mouth ...
Non-core vaccinations include that for Bordetella bronchiseptica, which is usually required by boarding facilities, obedience classes, dog shows and other places where the highly contagious kennel cough can spread. If your dog is often exposed to bodies of water -- ranging from streams to lakes -- your vet may recommend a vaccine against leptospirosis. This bacterial infection, which can prove fatal in some cases, is also spread via contaminated urine and can remain in the soil. If you travel a lot with your pet, or participate in dog shows, the canine influenza virus vaccine is recommended. While a vaccine is available for Lyme disease, many vets dont suggest it for their patients unless the dogs lifestyle puts him at particular risk for this debilitating disease.. ...
CRP is one of the proteins commonly referred to as acute phase reactants. CRP is distinguished by its rapid response to trauma or infection. Increased CRP levels have been found in dogs with arthritis, procitis or thrombophlebitis. Dogs with an increased number of leukocytes had significantly higher CRP levels than dogs with non-inflammatory leukograms. In addition, increased CRP levels have been documented in dogs infected with Ehrlichia canis or Bordetella bronchiseptica. ...
Nobivac Feline-Bb prevents diseases caused by Bordetella bronchiseptica. Healthy cats and kittens are protected as early as 72 hours post-vaccination.
Differentiation of Bvg-regulated gene expression.Comparative global expression analysis revealed unexpected complexity of the Bordetella BvgAS regulon and insights into possible evolutionary paths for virulence regulation among strains and species of an important group of bacterial pathogens. In particular, B. bronchiseptica, a pathogen and persistent commensal in a broad set of animal species, displayed a wide variety of gene expression profiles in vitro. These profiles may reflect spatially and/or temporally defined patterns during the infectious cycle. The spatial model proposes that colonization of different airway niches and the process of transmission require overlapping yet distinct sets of gene products, the expression of which is regulated by BvgAS in response to environmental conditions characteristic of those anatomic locations. Alternatively, or in addition, BvgAS may regulate a gene expression program in a temporally defined manner, facilitating the establishment of infection (49). ...
In healthy adult dogs, B. bronchiseptica typically causes no more than a mild illness. In puppies or in dogs with other underlying health issues, however, it can cause severe illness or even death in rare cases.. Diagnosis and Treatment. Although sophisticated testing is available, diagnosis is generally based on a history of exposure to infected dogs or a recent visit to a kennel, combined with the presence of signs of illness. In mild cases, treatment is generally supportive, as the disease typically resolves on its own unless a subsequent infection occurs. Precautionary antibiotics to prevent subsequent infection may be prescribed. In severe cases, treatment may consist of administration of antibiotics as well as medications to help your pet breathe more easily. Cough medication may also be prescribed if appropriate.. A harness, rather than a collar, is recommended for leash walking of ill dogs. A traditional collar puts pressure on already sensitive and irritated tracheal tissues and can ...
CT Beer Trail website (ctbeertrail.net) estimates that close to 15 brewing businesses have opened since 2010. News and events website serves as a gathering place for members and fans. Tastings and onsite tours at breweries draw fans as well.. ...
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Using antisera raised against serotype 2 and 3 fimbrial subunits from Bordetella pertussis, serologically related polypeptides were detected in Bordetella bronchiseptica, Bordetella parapertussis and Bordetella avium strains. The two B. pertussis fimbrial subunits, and three of the serologically related B. bronchiseptica polypeptides, were shown to be very similar in amino ... read more acid composition and N-terminal amino acid sequence. Homology was observed between the N-termini of these polypeptides, and fimbrial subunits from Escherichia coli, Haemophilus influenzae and Proteus mirabilis. A synthetic oligonucleotide probe, derived from the N-terminal sequence of the B. pertussis serotype 2 fimbrial subunit, was used to identify fimbrial genes in genomic Southern blots. The results suggested the presence of multiple fimbrial subunit genes in B. pertussis, B. bronchiseptica and B. parapertussis. The DNA probe was used to clone one of the three tentative fimbrial subunit genes detected in B. ...
Bordetella is a genus of small (0.2 - 0.7 µm), Gram-negative coccobacilli of the phylum Proteobacteria. Bordetella species, with the exception of B. petrii, are obligate aerobes, as well as highly fastidious, or difficult to culture. All species can infect humans. The first three species to be described (B. pertussis, B. parapertussis, B. bronchiseptica,); are sometimes referred to as the classical species. One of these (B. bronchiseptica) is also motile. B. pertussis and occasionally B. parapertussis cause pertussis or whooping cough in humans, and some B. parapertussis strains can colonise sheep. B. bronchiseptica rarely infects healthy humans, though disease in immunocompromised patients has been reported. B. bronchiseptica causes several diseases in other mammals, including kennel cough and atrophic rhinitis in dogs and pigs, respectively. Other members of the genus cause similar diseases in other mammals, and in birds (B. hinzii, B. avium). The Bordetella genus is named after Jules ...
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The genus Bordetella comprises several bacterial species that colonize the respiratory tract of mammals. It includes B. pertussis, a human-restricted pathogen that is the causative agent of Whooping Cough. In contrast, the closely related species B. bronchiseptica colonizes a broad range of animals as well as immunocompromised humans. Recent metagenomic studies have identified known and novel bordetellae isolated from different environmental sources, providing a new perspective on their natural history. Using phylogenetic analysis, we have shown that human and animal pathogenic bordetellae have most likely evolved from ancestors that originated from soil and water. Our recent study found that B. bronchiseptica can evade amoebic predation and utilize Dictyostelium discoideum as an expansion and transmission vector, which suggests that the evolutionary pressure to evade the amoebic predator enabled the rise of bordetellae as respiratory pathogens. Interactions with amoeba may represent the starting point
This vaccine offers effective, safe and effective atrophic rhinitis prevention in baby pigs. Contains avirulent live cultures of avirulent Bordetella bronchiseptica which colonize and block the adherence of disease-causing strains ...
Physical Exam. The Choice Package includes a nose-to-tail annual wellness physical exam.. 5-in-1 Vaccine + Lepto. This vaccination is considered a core vaccination for every dog, meaning every dog should receive this vaccination as puppies, then receive booster vaccines based on your veterinarians recommendation.. The causative agent of Leptospirosis is a bacterial organism that is highly contagious that infects humans and animals. Signs of infection in animals include fever, vomiting, diarrhea, anorexia, weakness, depression, and muscle pain. Without treatment, affected animals may succumb to kidney and/or liver failure.. Bordetella Vaccine. Bordetella bronchiseptica, a bacterial organism, is one of several major causes of infectious tracheobronchitis or Kennel Cough, an extremely contagious respiratory disease of dogs. The disease is spread by direct contact and airborne transmission. The highest risk includes dogs frequently attending dog parks, doggy day care, training classes, boarding, ...
Kennel cough in dogs is a respiratory canine infection caused by the canine parainfluenza virus and Bordetella bronchiseptica. When these pathogens attack your fur-baby, it will affect the respiratory tract lining and will cause inflammation of his airways. Kennel cough in dogs can be more complicated than we think as
Yes! Vaccines against parainfluenza and adenovirus type 2 (in combination with other vaccines) are routinely used as part of an adult dogs yearly checkup. Puppies are usually vaccinated for these in combination with distemper, hepatitis, and parvovirus in a series of immunizations. Specific, non-routine vaccines are also available for Bordetella bronchiseptica (another cause of canine cough). Although some veterinary practices do not use this vaccination routinely, it should be considered for pets that board, visit a daycare frequently, or for those whose veterinarian recommends it. It is important to note that the vaccines that are used to prevent this viral disease are made from only one of the over 100 different strains of the virus and therefore are not as effective against some strains as others. Some strains are not included in any vaccine; therefore, there is no prevention against them. Your veterinarian is in the best position to recommend a program of preventative health care ...
Bronchi-Shield Oral 25 Doses, BRONCHI-SHIELD ORAL is a unique Canine Infectious Respiratory Disease (CIRD) vaccine because it is the first live, avirulent Bordetella bronchiseptica vaccine licensed to be administered orally to
BronchiShield - Bronchi-Shield III is a vaccine that prevents diseases caused by Canine Adenovirus Type 1 and Type 2, Parainfluenza, and Bordetella Bronchiseptica. This vaccination includes modified versions of each live virus to help your dogs immune system recognize and resist each virus. It is also easy to dispense as it can be given intranasally. Bronchi-Shield III is recommended for healthy dogs that are at least 8 weeks of age. This package comes with 25 doses of the vaccine to vaccinate multiple dogs and/or to revaccinate dogs annually. Each of the viruses this product aims to prevent can be extremely dangerous to dogs, so order a pack of vaccinations for your dog today! Contains live modified viruses to prevent disease Contains 25 doses of the vaccine for revaccination, etc. Can be dispensed intranasally
Nobivac Intra-Trac3 ADT is for the prevention of Canine Adenovirus Type 2, Parainfluenza, Bordetella Bronchiseptica Vaccine (MLV). For INTRANASAL use in healthy dogs including pregnant females and healthy puppies.
0095] After the challenge with Bordetella bronchiseptica, general clinical observation was performed for each dog for 21 days, and its clinical symptoms were scored. The clinical scores were computed by scoring symptoms according to the following criteria every day during the observation period and adding them together. (1) Three points when body temperature (rectal temperature) is 40.0° C. or more, two points when 39.6 to 39.9° C., one point when 39.2 to 39.5° C.; (2) one point when hypodynamia is observed; (3) two points when serious anorexia is observed, one point when mild anorexia is observed; (4) one point when diarrhea is observed; (5) one point when vomiting is observed; (6) one point when dehydration is observed; (7) one point when lacrimation or eye discharge is observed in the eye; (8) three points when serious purulent nasal discharge is observed, two points when mild purulent nasal discharge is observed, one point when water-like nasal discharge is observed; (9) three points when ...
Ready to use lyophilised master mixes (8-well strips each) for detection of feline calicivirus, feline herpesvirus-1, Bordetella bronchiseptica, Chlamydophila felis, Mycoplasma felis and internal control. ...
When and how often laboratory tests are done may depend on many factors. The timing of laboratory tests may rely on the results or completion of other tests, procedures, or treatments. Lab tests may be performed immediately in an emergency, or tests may be delayed as a condition is treated or monitored. A test may be suggested or become necessary when certain signs or symptoms appear. Due to changes in the way your body naturally functions through the course of a day, lab tests may need to be performed at a certain time of day. If you have prepared for a test by changing your food or fluid intake, lab tests may be timed in accordance with those changes. Timing of tests may be based on increased and decreased levels of medications, drugs or other substances in the body. The age or gender of the person being tested may affect when and how often a lab test is required. Chronic or progressive conditions may need ongoing monitoring through the use of lab tests. Conditions that worsen and improve may ...
Pertussis toxin is coded by a multi-subunit protein complex. PCR assays focus on the promoter region of the pertussis toxin operon, which is well-characterized and is already used as a target for diagnostic PCR assays. This genetic region is not specific to B. pertussis as it can also be found in the genome of B. parapertussis and B. bronchiseptica. However, these other species contain mutations in their operon sequence, which prevent the expression of the actual toxin. These mutations provide a way to differentiate between the three species of Bordetella using melting temperatures in real-time PCR ...
... s have been suggested as antimicrobials able to remove Bordetella bronchiseptica biofilms. The mode of killing has ... Irie Y, O'toole GA, Yuk MH (September 2005). "Pseudomonas aeruginosa rhamnolipids disperse Bordetella bronchiseptica biofilms ...
... with probiotics against Bordetella bronchiseptica in mice". The Journal of Veterinary Medical Science. 72 (9): 1195-202. doi: ...
This is known to be caused by the Bordetella bronchiseptica bacterium. Hedgehogs uncommonly transmit a characteristic fungal ...
These include Bordetella bronchiseptica, Streptococcus phocae, Salmonella dublin, and S. choleraesuis. Corynebacterium caspium ...
"Role of phosphoglucomutase of Bordetella bronchiseptica in lipopolysaccharide biosynthesis and virulence". Infection and ...
There are multiple causative agents, the most common being the bacterium Bordetella bronchiseptica (found in 78.7% of cases in ... Schulz, B; Kurz, S; Balzer, H; Hartmann, K (September 2014). "Detection of Respiratory Viruses and Bordetella Bronchiseptica in ... "Simultaneous analysis of the nasal shedding kinetics of field and vaccine strains of Bordetella bronchiseptica". The Veterinary ... "Naturally occurring respiratory disease in a kennel caused by Bordetella bronchiseptica". The Cornell Veterinarian. 67 (2): 282 ...
... from Bordetella bronchiseptica". The FASEB Journal. 25 (1 Supplement): 714.2. doi:10.1096/fasebj.25.1_supplement.714.2. ISSN ...
"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica". ...
... parainfluenza and Bordetella bronchiseptica. Vaccinations must be valid for the entire quarantine period. The 'Rabies Antibody ...
Bordetella parapertussis and Bordetella bronchiseptica". Nature Genetics. 35 (1): 32-40. doi:10.1038/ng1227. PMID 12910271. CS1 ... 2003). "Comparative analysis of the genome sequences of Bordetella pertussis, ... and Bordetella. Achtman was one of the inventors of multilocus sequence typing. His research has been funded by the ...
Bordetella parapertussis and Bordetella bronchiseptica". Nature Genetics. 35 (1): 32-40. doi:10.1038/ng1227. PMID 12910271. CS1 ... 2003). "Comparative analysis of the genome sequences of Bordetella pertussis, ...
Bordetella bronchiseptica has been identified in cats with owners that also are infected with this pathogen. Individuals having ...
Bordetella pertussis. Bordetella bronchiseptica and Bordetella parapertussis, also able to cause pertussis-like symptoms, also ... Vaccination against Bordetella pertussis is used in infancy to prevent whooping cough. The recent switch from whole-cell ... Adenylate cyclase toxin is a virulence factor produced by some members of the genus Bordetella. Together with the pertussis ... Differences between the toxins of different Bordetella species are mainly in the calcium-binding domain. The toxin is secreted ...
Bordetella bronchiseptica, and Salmonella. Many of the immune activating abilities of LPS can be attributed to the lipid A unit ...
Kennel cough is an infectious respiratory disease which can be caused by one of several viruses or by Bordetella bronchiseptica ...
In veterinary medicine, vaccination against Bordetella bronchiseptica, a cause of kennel cough, can be delivered by the nasal ...
... and Bordetella bronchiseptica sensitive to tulathromycin. Sheep: Treatment of the early stages of infectious pododermatitis ( ...
The most notable of these are Bordetella bronchiseptica, one of the causes of kennel cough, Leptospira sp, which cause ... Bordetella bronchiseptica, parainfluenza virus, and canine coronavirus, should be made between an owner and a veterinarian, ...
Feline calicivirus-(cat respiratory disease) Bordetella bronchiseptica-(cat kennel cough) Chlamydophila felis-(chlamydia) In ...
... such as Bordetella bronchiseptica, has likely increased in recent years. In some cases, most notably rabies, the parallel ... Bordetella, canine parainfluenza virus, and Lyme disease, among others. Cases of veterinary vaccines used in humans have been ...
Bordetella bronchiseptica Chlamydophila felis Feline calicivirus Feline viral rhinotracheitis (FVR) FHV-1 Cat-scratch disease ...
... bordetella bronchiseptica, porcine parvovirus, and Erysipelothrix rhusiopathiae among others. It is particularly important to ...
... a presentation of congenital syphilis A disease of rabbits caused by the bacterium Bordetella bronchiseptica Gund Snuffles, ...
In addition to being at risk of disease from common pathogens such as Bordetella bronchiseptica and Escherichia coli, rabbits ...
Bartonella Bartonella henselae Bartonella quintana Bordetella Bordetella bronchiseptica Bordetella pertussis Borrelia ...
These include: Feline leukemia virus (FeLV) Feline immunodeficiency virus (FIV) Chlamydia felis Bordetella bronchiseptica ...
Bordetella MeSH B03.440.400.425.117.075.099 - Bordetella avium MeSH B03.440.400.425.117.075.200 - Bordetella bronchiseptica ... Bordetella MeSH B03.660.075.027.075.024 - Bordetella avium MeSH B03.660.075.027.075.050 - Bordetella bronchiseptica MeSH ... B03.660.075.027.075.590 - Bordetella parapertussis MeSH B03.660.075.027.075.600 - Bordetella pertussis MeSH B03.660.075.027.800 ... MeSH B03.440.400.425.117.075.540 - Bordetella parapertussis MeSH B03.440.400.425.117.075.550 - Bordetella pertussis MeSH ...
Bordetella parapertussis and Bordetella bronchiseptica". Nature Genetics. 35 (1): 32-40. doi:10.1038/ng1227. PMID 12910271. ... and Clinical Manifestations of Respiratory Infections Due to Bordetella pertussis and Other Bordetella Subspecies". Clinical ... 1991). "Effects of Bordetella pertussis infection on human respiratory epithelium in vivo and in vitro". Infection and Immunity ... Luker, K. E.; Collier, J. L.; Kolodziej, E. W.; Marshall, G. R.; Goldman, W. E. (1993). "Bordetella pertussis Tracheal ...
B. bronchiseptica is gram-negative. The most thoroughly studied of the Bordetella species are B. bronchiseptica, B. pertussis ... After 42 days, the dogs were exposed to Bordetella bronchiseptica. This study determined that the live intranasal Bordetella ... The Bordetella vaccine specifically targets the genus and species Bordetella bronchiseptica, the species typically responsible ... The three most common species of Bordetella are B. pertussis, B. parapertussis and B. bronchiseptica. These species are known ...
... such as Bordetella bronchiseptica, has likely increased in recent years.[104] In some cases, most notably rabies, the parallel ...
... such as Bordetella bronchiseptica, has likely increased in recent years.[118] In some cases, most notably rabies, the parallel ... Bordetella, canine parainfluenza virus, and Lyme disease, among others. ...
Bordetella parapertussis and Bordetella bronchiseptica". Nature Genetics. 35 (1): 32-40. doi:10.1038/ng1227. PMID 12910271. ... The genus Bordetella contains nine species: B. pertussis B. parapertussis, B. bronchiseptica, B. avium, B. hinzii, B. holmesii ... Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus of the genus Bordetella, and the ... Nieves DJ, Heininger U (2016). "Bordetella pertussis". Bordetella pertussis. Microbiology Spectrum. 4. pp. 311-339. doi:10.1128 ...
... bronchiseptica. Emsley, P.; Charles, I. G.; Fairweather, N. F.; Isaacs, N. W. (1996). "Structure of Bordetella pertussis ... PRN is purified from Bordetella pertussis and is used for the vaccine production as one of the important components of ... Pertactin adheres to only ciliated epithelial cells of B. bronchiseptica in vivo. However, in vitro, PRN does not adhere to ... Emsley P, Charles IG, Fairweather NF, Isaacs NW (May 1996). "Structure of Bordetella pertussis virulence factor P.69 pertactin ...
Both lineages are thought to have evolved from a B. bronchiseptica-like ancestor. This disease can be symptomatic or ... Bordetella parapertussis is a small Gram-negative bacterium of the genus Bordetella that is adapted to colonise the mammalian ... Wolfe D, Goebel E, Bjornstad O, Restif O, Harvil E (2007). "The O Antigen Enables Bordetella parapertussis To Avoid Bordetella ... "Clinical characteristics of illness caused by Bordetella parapertussis compared with illness caused by Bordetella pertussis". ...
B. bronchiseptica and B. avium are respiratory pathogens of other animals. B. hinzii is not pathogenic and colonizes the ... Bordetella endotoxins are unique to the genus, species, and strain. B. trematum is the only Bordetella species with a semirough ... It is unique in being oxidase negative, since all other species of Bordetella are oxidase positive. Bordetella trematum may be ... Bordetella species typically infect the respiratory tracts of humans, but B. trematum has never been isolated from a human or ...
... for Bordetella bronchiseptica (Public Health Agency of Canada) Genetic sequences of the Bordetella bronchiseptica complex ( ... Bordetella bronchiseptica is a small, gram-negative, rod-shaped bacterium of the genus Bordetella. It can cause infectious ... J Clin Microbiol 31(7): 1838-44 "Prevention and control of Bordetella bronchiseptica infection in cats". Intervet/Schering- ... Role of canine parainfluenza virus and Bordetella bronchiseptica in kennel cough. Am J Vet Res 45(9): 1862-6. Burns, E. H., Jr ...
... for Bordetella bronchiseptica (Public Health Agency of Canada) Genetic sequences of the Bordetella bronchiseptica complex ( ... Bordetella bronchiseptica is a small, gram-negative, rod-shaped bacterium of the genus Bordetella. It can cause infectious ... J Clin Microbiol 31(7): 1838-44 "Prevention and control of Bordetella bronchiseptica infection in cats". Intervet/Schering- ... Role of canine parainfluenza virus and Bordetella bronchiseptica in kennel cough. Am J Vet Res 45(9): 1862-6. Burns, E. H., Jr ...
Bordetella bronchiseptica (Ferry 1912) Moreno-Lopez 1952. › Bordetella bronchiseptica@. › Brucella bronchiseptica. › Brucella ... Bordetella. Strains i. › 240/2. › 7865. › ATCC 31437 / Bb55. › ATCC 4617 / NCIB 9935 / NCTC 8344 / NRRL B-140, NCTC 8344. › ... "Brucella bronchiseptica" (Ferry 1912) Topley and Wilson 1929. › "Haemophilus bronchisepticus" (Ferry 1912) Wilson and Miles ...
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Bordetella bronchiseptica ATCC ® 10580™ Designation: 03127 TypeStrain=False Application: Media testing Quality control strain ... Bordetella bronchiseptica (Ferry) Moreno-Lopez (ATCC® 10580™) Strain Designations: 03127 / Type Strain: no / Biosafety Level: 2 ...
Bordetella bronchiseptica ATCC ® 4617™ Designation: NRRL B-140 TypeStrain=False Application: Assay of colistimethate sodium ... Bordetella bronchiseptica (Ferry) Moreno-Lopez (ATCC® 4617™) Strain Designations: NRRL B-140 / Type Strain: no / Biosafety ...
Bordetella bronchiseptica Bordetella bronchiseptica is a minute, gram-negative rod-shaped coccobacilli about .5-1 micrometers ... 4,9] Bordetella bronchiseptica is mostly closely related to Bordetella pertussis and Bordetella parapertussis, both of which is ... Bordetella bronchiseptica and the genus Bordetella in general do not use sugars as a carbon source. As expected, the genes ... Bordetella bronchiseptica. From MicrobeWiki, the student-edited microbiology resource. Revision as of 06:55, 5 June 2007 by ...
Bordetella bronchiseptica Description and Significance. Bordetella bronchiseptica is a minute, gram-negative rod-shaped ... Bordetella bronchiseptica is mostly closely related to Bordetella pertussis and Bordetella parapertussis, both of which is ... Bordetella bronchiseptica is most known for causing "kennel cough" in dogs and brochopnemonia in cats. [2,8] Bordetella ... Bordetella bronchiseptica and the genus Bordetella in general do not use sugars as a carbon source. As expected, the genes ...
A naturally occurring analog to phage display, the Bordetella bronchiseptica bacteriophage (BP) employs a highly variable ... Bordetella Is the Subject Area "Bordetella" applicable to this article? Yes. No. ...
Clonal diversity and host distribution in Bordetella bronchiseptica.. J M Musser, D A Bemis, H Ishikawa, R K Selander ... Clonal diversity and host distribution in Bordetella bronchiseptica. Message Subject (Your Name) has forwarded a page to you ... A total of 303 isolates of Bordetella bronchiseptica recovered from 11 host species were characterized by the electrophoretic ... The population structure of B. bronchiseptica is clonal, and its genetic diversity is limited in comparison with most other ...
... of Bordetella bronchiseptica, Gram-negative, aerobic, motile, coccobacillus prokaryote (bacterium). Bordetella bronchiseptica ... of Bordetella bronchiseptica, Gram-negative, aerobic, motile, coccobacillus prokaryote (bacterium). Bordetella bronchiseptica ... It is related to Bordetella pertussis, the obligate human pathogen, that causes pertussis or whooping cough. B. bronchiseptica ... Humans are not natural carriers of B. bronchiseptica. Magnification: x4,400 when shortest axis printed at 25 millimetres. ...
Bordetella bronchiseptica. Mutation(s): 0 Gene Names: BbLPS1.16, wbmF, B7P10_00725. Find proteins for O87989 (Bordetella ... The pathogenic bacteria Bordetella parapertussis and Bordetella bronchiseptica express a lipopolysaccharide O antigen ... The pathogenic bacteria Bordetella parapertussis and Bordetella bronchiseptica express a lipopolysaccharide O antigen ... Crystal structure of the Bordetella bronchiseptica enzyme WbmF in complex with NADH. *DOI: 10.2210/pdb2Q1S/pdb ...
Viable cell numbers (cfu/ml) of the B. pertussis strains and a rough strain of B. bronchiseptica (CSU-P-1) d … ... The viability of four strains of Bordetella bronchiseptica, two strains of B. pertussis and one strain of B. parapertussis ... The viability of four strains of Bordetella bronchiseptica, two strains of B. pertussis and one strain of B. parapertussis ... Serum sensitivity and lipopolysaccharide characteristics in Bordetella bronchiseptica, B. pertussis and B. parapertussis J Med ...
Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are closely related Gram-negative beta- ... Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.. ... B. parapertussis can also cause whooping cough, and B. bronchiseptica causes chronic respiratory infections in a wide range of ... We sequenced the genomes of B. bronchiseptica RB50 (5,338,400 bp; 5,007 predicted genes), B. parapertussis 12822 (4,773,551 bp ...
Human infections associated with Bordetella bronchiseptica. Message Subject (Your Name) has forwarded a page to you from ... Human infections associated with Bordetella bronchiseptica.. B F Woolfrey, J A Moody ... This study examines the potential of Bordetella bronchiseptica to act as a human pathogen. After encountering two patients from ... Evidence suggests that B. bronchiseptica may be rarely encountered as a commensal or colonizer of the respiratory tract of ...
Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes.. B Aricò, R ... Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes.. B Aricò, R ... Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes.. B Aricò, R ... Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes. Message Subject ...
The BvgAS signal transduction system in Bordetella spp. mediates a transition between infectious (Bvg+) and non-infectious (Bvg ... The BvgAS virulence control system regulates type III secretion in Bordetella bronchiseptica Mol Microbiol. 1998 Jun;28(5):945- ... we identified a gene expressed in the Bvg+ phase of Bordetella bronchiseptica that shows a high degree of sequence similarity ... An in-frame deletion of bscN in B. bronchiseptica leads to decreased secretion of several proteins, decreased cytotoxicity ...
The proliferation of Bordetella bronchiseptica-reactive spleen cells occurred during the acute phase of infection. T cells from ... Intranasal inoculation of Bordetella bronchiseptica in mice induces long-lasting antibody and T-cell mediated immune responses. ... This observation could be due to the fact that Bordetella bronchiseptica may persist intracellularly in the host as it was ... These results suggest that Bordetella bronchiseptica infection induces primarily a Th1-type T-cell response. Importantly, the ...
En art av Bordetella som är en parasit och patogen. Den förekommer i andningsvägarna hos däggdjur, såväl vilda som husdjur, och ... Bordetella bronchiseptica. Bordetella bronchiseptica. Svensk definition. En art av Bordetella som är en parasit och patogen. ... A species of BORDETELLA that is parasitic and pathogenic. It is found in the respiratory tract of domestic and wild mammalian ... Alcaligenes bronchisepticus - Brucella bronchiseptica - Haemophilus bronchisepticus - Alcaligenes bronchicanis - Bacterium ...
B. bronchiseptica acts as a primary or secondary pathogen in feline respiratory disease. ... Nobivac Feline-Bb is for the intranasal vaccination of healthy kittens and cats for prevention of disease caused by Bordetella ... Bordetella Bronchiseptica Vaccine. Nobivac Feline-Bb is an intranasal vaccine containing an avirulent live culture of ... bronchiseptica may be the sole infectious agent in feline URI.(1) (2) Clinical signs associated with B. bronchiseptica ...
Nobivac Feline-Bb [Bordetella bronchiseptica], 25 Single Dose Vials (1010958). 5.00 stars, based on 1 reviews ...
Bordetella bronchiseptica RB50. Mutation(s): 3 Gene Names: 2660008, BB2244. EC: 3.4. ... Find proteins for A0A0H3LUS8 (Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)) ... X-Ray Crystal Structure of Phage-related Protein BB2244 from Bordetella bronchiseptica. Northeast Structural Genomics ... Crystal Structure of the phage-related conserved hypothetical protein BB2244 from Bordetella bronchiseptica, Northeast ...
Bordetella pertussis (strain ATCC 9797 / DSM 5571 / NCTC 10739 / 18323). Bordetella pertussis H921. Bordetella bronchiseptica ( ... Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus). Bordetella parapertussis ( ... Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251). Bordetella pertussis 2356847. Bordetella pertussis B1920. ... Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus). ,p>This subsection of the ...
Bordetella bronchiseptica derived from ATCC® 10580™*, SKU: 0655KKWIK-STIK™ 6 PackDETAILS ...
NAME: Bordetella bronchiseptica. SYNONYM OR CROSS REFERENCE: Kennel cough (dogs) Footnote 1, Haemophilus bronchiseptica ... SURVIVAL OUTSIDE HOST: Bordetella species survive only for a few hours in respiratory secretions Footnote 10. B. bronchiseptica ... Porter, J. F., & Wardlaw, A. C. (1993). Long-term survival of Bordetella bronchiseptica in lakewater and in buffered saline ... Belen, O., Campos, J. M., Cogen, P. H., & Jantausch, B. A. (2003). Postsurgical meningitis caused by Bordetella bronchiseptica ...
The ATCC Licensed Derivative Emblem, the ATCC Licensed Derivative word mark and the ATCC catalog marks are trademarks of ATCC. Microbiologics, Inc. is licensed to use these trademarks and to sell products derived from ATCC® cultures. Look for the ATCC Licensed Derivative © Emblem for products derived from ATCC© cultures. ...
Of the Bordetella genus,Bordetella bronchiseptica is the principle effector of respiratory disease in a wide range of mammals ( ... Cloning and sequence of the Bordetella bronchiseptica adenylate cyclase-hemolysin-encoding gene-comparison with the Bordetella ... Characterization of the common antigenic lipopolysaccharide O-chains produced by Bordetella bronchiseptica and Bordetella ... Bordetella bronchiseptica pneumonia with shock in an immunocompetent patient.Scand. J. Infect. Dis.281996197198. ...
Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells.. C A Guzman, M Rohde, M Bock, K N ... Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells.. C A Guzman, M Rohde, M Bock, K N ... Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells.. C A Guzman, M Rohde, M Bock, K N ... Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells. Message Subject (Your Name) has ...
OBJECTIVE: The objective of this study was to determine the ability of a modified live intranasal Bordetella bronchiseptica ... DEMONSTRATION OF ONE YEAR DURATION-OF-IMMUNITY FOR A FELINE BORDETELLA BRONCHISEPTICA VACCINE ... Twenty-four vaccinated cats and 12 controls were challenged with a virulent strain of B. bronchiseptica six-months after ...
... infecting Bordetella bronchisepticawas isolated from wastewater collected at a swine farm in China. Phage vB_BbrM_PHB04 ... Yacoub AT, Katayama M, Tran J, Zadikany R, Kandula M, Greene J (2014) Bordetella bronchiseptica in the immunosuppressed ... A novel virulent bacteriophage, vB_BbrM_PHB04, infecting Bordetella bronchiseptica was isolated from wastewater collected at a ... Goodnow RA (1980) Biology of Bordetella bronchiseptica. Microbiol Res 44(4):722Google Scholar ...
Find details on Bordetella bronchiseptica infection in cats including diagnosis and symptoms, pathogenesis, prevention, ... Most cats are exposed to the bacteria Bordetella bronchiseptica before adulthood.. Print off the owner factsheet on Bordetella ... Binns S H, Dawson S, Speakman A J et al (1999) Prevalence and risk factors for feline Bordetella bronchiseptica infection. Vet ... Coutts A J, Dawson S, Binns S H et al (1996) Studies on natural tranmission of Bordetella bronchiseptica in cats. Vet Microbiol ...
  • It is related to Bordetella pertussis, the obligate human pathogen, that causes pertussis or whooping cough. (sciencephoto.com)
  • This study examines the potential of Bordetella bronchiseptica to act as a human pathogen. (asm.org)
  • Research has demonstrated that B. bronchiseptica acts as a primary or secondary pathogen in feline respiratory disease. (medi-vet.com)
  • B. bronchiseptica is primarily a respiratory tract pathogen found in a variety of animals Footnote 5 . (canada.ca)
  • We have studied the interaction between the respiratory pathogen Bordetella bronchiseptica and murine spleen dendritic cells, important antigen-presenting cells that are found in the airway epithelium. (asm.org)
  • Infection may arise independent of other pathogens as B. bronchiseptica is a primary pathogen. (vetstream.com)
  • OVERVIEW: Bordetella bronchiseptica is a Gram-negative bacterium that colonises the respiratory tract of mammals and is considered to be a primary pathogen of domestic cats. (uzh.ch)
  • B. bronchiseptica is a pathogen that can cause serious infection in humans, especially in immunocompromised or immunoincompetent individuals. (biomedcentral.com)
  • B bronchiseptica may play the role of either primary pathogen or secondary invader. (liverpool.ac.uk)
  • Bordetella bronchiseptica (Bb) is a primary pathogen of domestic cats, particularly in high population density conditions such as rescue shelters and multicat households. (abcdcatsvets.org)
  • Pneumonia, different in extent, was produced in primarily specific pathogen free pigs by intratracheal and intranasal application of eight Bordetella isolates. (meta.org)
  • Bordetella bronchiseptica is a well-known veterinary pathogen, but its implication in human disease is probably not fully recognized. (cdc.gov)
  • Bordetella bronchiseptica is a pathogen of laboratory, domestic, and wild animals and sometimes of humans. (pasteur.fr)
  • In AIDS patients with chronic cough, B. bronchiseptica should be considered as a pathogen causing opportunistic infection. (kowsarpub.com)
  • B. bronchiseptica is a respiratory pathogen which may cause acute or chronic bronchopneumonia and is found in many animals, including dogs, cats, pigs, and rabbits, as well as humans ( 11 , 12 ). (cdc.gov)
  • B. bronchiseptica is an uncommon but recognized human pathogen. (elsevier.com)
  • Clinical and pathological effects of the dermonecrotic toxin of Bordetella bronchiseptica and Pasteurella multocida in specific-pathogen-free piglets. (elsevier.com)
  • Fingerprint Dive into the research topics of 'Clinical and pathological effects of the dermonecrotic toxin of Bordetella bronchiseptica and Pasteurella multocida in specific-pathogen-free piglets. (elsevier.com)
  • Infection with Bordetella bronchiseptica ( Bb ), a pathogen involved in canine infectious respiratory disease complex, can be confirmed using culture or qPCR. (biomedcentral.com)
  • In pigs, B. bronchiseptica and Pasteurella multocida act synergistically to cause atrophic rhinitis, a disease resulting in arrested growth and distortion of the turbinates in the nasal terminus (snout). (wikipedia.org)
  • Severe cases of illness due to B. bronchiseptica are often found to be co-infections with toxigenic Pasteurella multocida Footnote 4 . (canada.ca)
  • Interaction of Bordetella bronchiseptica, Pasteurella multocida, and fumonisin B1 in the porcine respiratory tract as studied by computed tomography. (semanticscholar.org)
  • The interaction of Bordetella bronchiseptica, toxigenic Pasteurella multocida serotype D, and the mycotoxin fumonisin B(1) (FB(1)) was studied. (semanticscholar.org)
  • Silbernagel, "Pasteurella multocida and Bordetella bronchiseptica infections in rabbits," Journal of Clinical Microbiology, vol. (thefreedictionary.com)
  • Estudio prospectivo de la neumonia enzootica por Pasteurella multocida y Bordetella bronchiseptica en dos granjas cuniculas en la altillanura de Bogota. (thefreedictionary.com)
  • This study aims to monitor the prevalence of toxigenic Bordetella bronchiseptica (Bb) and Pasteurella multocida (Pm) in nursing and finishing animals by the RHINICheck test (PCR in oral fluids), and to evaluate the incidence of progressive atrophic rhinitis (PAR) in animals slaughtered at commercial meatpacking units. (hipra.com)
  • Bordetella (B.) bronchiseptica is a causative agent of swine atrophic rhinitis that promotes colonization of the mucous membrane of the swine nasal cavity by Pasteurella (P.) multocida. (bvsalud.org)
  • The role of dermonecrotic toxin (DNT) of Bordetella bronchiseptica and Pasteurella multocida, purified by repeated chromatography in Sephacryl S-200 gel, in the pathogenesis of atrophic rhinitis (AR) of swine was studied bacteriologically, clinically and pathologically. (elsevier.com)
  • Rhiniseng is a vaccine containing a non-toxic recombinant derivative of the Pasteurella multocida toxin and inactivated Bordetella bronchiseptica cells (inactivated means that the bacteria are killed so that they cannot cause the disease anymore). (europa.eu)
  • It is used to reduce the clinical signs and lesions of a disease called progressive and non-progressive atrophic rhinitis, as well as to reduce weight loss associated with Bordetella bronchiseptica and Pasteurella multocida infections during the fattening period. (europa.eu)
  • Abstract: Bordetella bronchiseptica is an uncommon cause of respiratory infection in humans generally occurring in immunocompromised individuals exposed to infected animals. (elsevier.com)
  • Nobivac Feline-Bb is an intranasal vaccine containing an avirulent live culture of Bordetella bronchiseptica. (medi-vet.com)
  • The objective of this study was to determine the ability of a modified live intranasal Bordetella bronchiseptica vaccine (Nobivac-Bb) to prevent disease in cats for a period of one year following vaccination. (vin.com)
  • In some cases, canine cough has been seen in dogs that were current on their Bordetella vaccine, which suggests that the vaccination does not offer immunity to this particular strain of canine cough. (greenacreskennel.com)
  • Three groups of approximately eight-week-old beagles were vaccinated once with 1 ml of placebo vaccine (oral, n=9), 1 ml of Recombitek® Oral Bordetella (oral, n=10) or 1 ml Nobivac® Intra-Trac 3 (intranasal, 0.5 ml/nostril, n=10). (bmj.com)
  • Eight of nine dogs in the placebo group and no dogs in the Recombitek® Oral Bordetella or Nobivac® Intra-Trac 3 vaccine groups developed spontaneous cough of two or more consecutive days (disease case definition). (bmj.com)
  • Since intranasal vaccines were most frequently observed to have the best efficacy, this study was designed to compare the efficacy of a newly developed oral vaccine with an established intranasal vaccine against a B bronchiseptica challenge seven days after vaccination. (bmj.com)
  • Other vaccines, such as the rabies and Bordetella vaccines, may be given in addition to the canine distemper/parvo combination vaccine. (vetstreet.com)
  • Based on your dog's risk for exposure, your veterinarian may recommend vaccinating your dog against Bordetella in addition to administering the canine distemper combination vaccine. (vetstreet.com)
  • An intranasal B. bronchiseptica vaccine is available in addition to the traditional injectable vaccine. (vetsecure.com)
  • There are many commercial vaccines for atrophic rhinitis , including B. bronchiseptica as a killed vaccine antigen (Ag). (bvsalud.org)
  • Can a puppy get kennel cough after receiving Bordetella Bronchiseptica vaccine? (treatmentforkennelcough.com)
  • Most dogs probably prefer the nasal version of the Bordetella vaccine to the sting of the needle. (howstuffworks.com)
  • One way you can help your dog, cat, guinea pig, rabbit or pig avoid kennel cough is by immunizing with the Bordetella vaccine. (howstuffworks.com)
  • A total of 303 isolates of Bordetella bronchiseptica recovered from 11 host species were characterized by the electrophoretic mobilities of 15 metabolic enzymes, and 21 distinctive multilocus genotypes (electrophoretic types) were distinguished on the basis of allele profiles at the enzyme loci. (asm.org)
  • Prüller S, Rensch U, Meemken D, Kaspar H, Kopp PA, Klein G, Kehrenberg C (2015) Antimicrobial susceptibility of Bordetella bronchiseptica isolates from swine and companion animals and detection of resistance genes. (springer.com)
  • Antimicrobial Susceptibility of Bordetella bronchiseptica Isolates. (thefreedictionary.com)
  • The purpose of this study was to determine the clinical significance of 36 B. bronchiseptica isolates from respiratory samples of 22 patients. (cdc.gov)
  • In the present study some characteristics of the virulence of B. bronchiseptica isolates of different origin were studied. (pasteur.fr)
  • The B. petrii isolates were compared with other B. petrii isolates collected from humans or the environment and with isolates of B. pertussis, B. parapertussis, B. bronchiseptica, and B. holmesii, obtained from human respiratory tract infections. (cdc.gov)
  • The population structure of B. bronchiseptica is clonal, and its genetic diversity is limited in comparison with most other pathogenic bacteria, perhaps reflecting a relatively recent origin of the species. (asm.org)
  • The pathogenic bacteria Bordetella parapertussis and Bordetella bronchiseptica express a lipopolysaccharide O antigen containing a polymer of 2,3-diacetamido-2,3-dideoxy-l-galacturonic acid. (rcsb.org)
  • Using differential display, arbitrary-primed polymerase chain reaction (PCR), we identified a gene expressed in the Bvg+ phase of Bordetella bronchiseptica that shows a high degree of sequence similarity to a locus involved in providing energy for type III secretion in pathogenic gram-negative bacteria (yscN in Yersinia spp. (nih.gov)
  • The LPS of the related bacterium Bordetella pertussis displays a structure that generally typifies that of nonenteric bacteria. (asm.org)
  • Most cats are exposed to the bacteria Bordetella bronchiseptica before adulthood. (vetstream.com)
  • The most prevalent of the bacteria that cause this illness is Bordetella bronchiseptica. (greenacreskennel.com)
  • In addition, some vaccinations for diseases that are zoonotic such as leptospirosis or Bordetella bronchiseptica do not prevent an animal from shedding the bacteria if the animal does happen to be come infected. (thefreedictionary.com)
  • Upper respiratory infection caused by Bordetella bacteria. (revivalanimal.com)
  • Among the putative Bordetella transcription factors are a number of genes belonging to the extracytoplasmic function (ECF) group of alternative sigma factors, some of which are known to mediate cell envelope stress responses in other bacteria. (biomedcentral.com)
  • After infection with virulent B. bronchiseptica a very early synthesis and a persistence of anti-adenylate cyclase-hemolysin and anti-filamentous hemagglutinin antibodies were observed in the sera of infected mice, suggesting a persistence of the bacteria or of its antigens. (pasteur.fr)
  • Particularly, conservation of BB3394 in sequenced B. bronchiseptica genomes suggests the importance of this gene for bacteria normal physiology. (conicet.gov.ar)
  • A medium was developed that in most instances allowed the isolation from pigs of Bordetella (Alcaligenes) bronchiseptica in pure, or virtually pure, culture from such sites as the nasal cavity, which contains many other bacteria. (meta.org)
  • Bordetella bronchiseptica is an easily contracted bacteria that causes a hacking cough or, occasionally, a snotty nose. (vetstreet.com)
  • Bordetella bronchiseptica is one of several organisms included on a short list of bacteria and viruses responsible for this kennel cough syndrome. (vetstreet.com)
  • The most thoroughly studied of the Bordetella species are B. bronchiseptica, B. pertussis and B. parapertussis, and the pathogenesis of respiratory disease caused by these bacteria has been reviewed. (wikipedia.org)
  • Other bacteria recycle this molecule back into the cytoplasm, but in Bordetella and Neisseria gonorrhoeae, it is released into the environment. (wikipedia.org)
  • This intermediate (Bvgi) phenotype can be reproduced in wild-type B. bronchiseptica by growth of the bacteria in a medium containing intermediate concentrations of the BvgAS modulator, nicotinic acid. (wikipedia.org)
  • Viruses such as canine adenovirus, canine distemper virus, canine parainfluenza virus, canine respiratory coronavirus, pneumovirus and influenza A virus and bacteria other than B. bronchiseptica such as Mycoplasma cynos and Streptococcus equi subsp. (biomedcentral.com)
  • Like all vaccines, Bordetella works by injecting a small amount of the bacteria or virus into the bloodstream of the animal. (howstuffworks.com)
  • Bordetella bronchiseptica is a small, gram-negative, rod-shaped bacterium of the genus Bordetella. (wikipedia.org)
  • Bordetella bronchiseptica is a bacterium that causes respiratory disease in dogs. (vetstreet.com)
  • Bordetella bronchiseptica is a bacterium associated with a highly contagious respiratory disease in dogs. (vetsecure.com)
  • Bordetella bronchiseptica is a mandatory aerobic bacterium, which has small irregularly stained Gram-negative pleomorphic coccobacillus form. (kowsarpub.com)
  • Bordetella bronchiseptica is a zoonotic bacterium and it can cause infection in most of the mammalian species such as cat, dog, horse, rabbit, and pig. (kowsarpub.com)
  • According to the taxonomical classification, the bacterium B. bronchiseptica belongs to the Proteobacteria phylum, the Alcaligenaceae family and the Bordetella genus [ 7 ]. (biomedcentral.com)
  • B. bronchiseptica does not express pertussis toxin, which is one of the characteristic virulence factors of B. pertussis, but it has the genes to do so, highlighting the close evolutionary relationship between the two species. (wikipedia.org)
  • Bordetella species. (wikipedia.org)
  • Fimbriae and determination of host species specificity of Bordetella bronchiseptica. (wikipedia.org)
  • It is believed that the species diverged 3.5 million years ago through decay of the Bordetella brochiseptica genome, as seen through a large-scale gene loss of the two subsequent species. (kenyon.edu)
  • Pertussis toxin, the major virulence factor of Bordetella pertussis, is not produced by the closely related species Bordetella parapertussis and Bordetella bronchiseptica. (asm.org)
  • The changes (mostly base pair substitutions) in many cases are identical in B. parapertussis and B. bronchiseptica, suggesting that these two species derive from a common ancestor. (asm.org)
  • A species of BORDETELLA that is parasitic and pathogenic. (ki.se)
  • This strict aerobe is motile by peritrichous flagella and is capable of growing rapidly at 35 o C to 37 o C Footnote 4 , Footnote 5 and is relatively simple in its nutritional requirements as compared to other Bordetella species Footnote 5 . (canada.ca)
  • Of the 9 species of Bordetella ( B. ) identified to date, B. bronchiseptica , B. parapertussis and B. holmesii are associated with respiratory infections in humans and other mammals. (biomedcentral.com)
  • Veterinarians have been aware for many years that Bordetella bronchiseptica (Bb) causes disease in dogs, rabbits, pigs, and other species. (thefreedictionary.com)
  • B. bronchiseptica is not host-specific and can be transmitted from one animal species (e. g. dog) to another (e. g. cat) and also to humans (zoonosis! (laboklin.com)
  • Bordetella species are important respiratory pathogens that possess a large number of putative transcription factors. (biomedcentral.com)
  • Despite their importance, no cell envelope stress responses have yet been identified or implicated in pathogenesis in Bordetella species. (biomedcentral.com)
  • Furthermore, we showed that its immunological and protective properties were different from that of B. pertussis adenylate cyclase-hemolysin, confirming that Bordetella species are immunologically different. (pasteur.fr)
  • Bordetella species utilize the BvgAS (Bordetella virulence gene) two-component signal transduction system to sense the environment and regulate gene expression among at least three phases: a virulent Bvg+ phase, a nonvirulent Bvg- phase, and an intermediate Bvgi phase. (mendeley.com)
  • Three groups of monoclonal antibodies (mAbs) were produced that would be useful for immunochemical typing and diagnosis of infections due to Bordetella species, and for the structural analysis of their lipopolysaccharides. (microbiologyresearch.org)
  • However, 2 other Bordetella species, B. bronchiseptica and B. holmesii , behave differently and are able to persist inside their hosts. (cdc.gov)
  • Unlike the "classical" pathogenic species, B. pertussis and B. parapertussis , B. petrii, B. holmesii, and B. bronchiseptica, have the ability to acquire or exchange genomic regions ( 20 , 21 ). (cdc.gov)
  • Most notably, Bordetella bronchiseptica may ocassionally infect people, especially those with respiratory disease or immune compromise.To prevent cross-species transmission as well as reduce stress for all concerned, it is always ideal to house ill animals separately by species. (treatmentforkennelcough.com)
  • Bordetella species, with the exception of B. petrii, are obligate aerobes, as well as highly fastidious, or difficult to culture. (wikipedia.org)
  • Role of canine parainfluenza virus and Bordetella bronchiseptica in kennel cough. (wikipedia.org)
  • Kennel cough (dogs) Footnote 1 , Haemophilus bronchiseptica Footnote 2 , Haemophilus bronchisepticus, Brucella bronchiseptica , Bacillus suisepticus , Alcaligenes bronchicanis , Bacillus bronchisepticus , Alcaligenes bronchisepticus , and atrophic rhinitis (swine) Footnote 3 . (canada.ca)
  • Bordetella pertussis is the cause of whooping cough in humans while Bordetella bronchiseptica is associated with kennel cough in dogs. (thefreedictionary.com)
  • Bordetella 속에는 4가지 종이 포함되어 있는데, 그중에서 Bordetella bronchiseptica 는 토끼, 기니아 피그, 개 등의 야생 포유류의 상기도에 공생하여 기관기관지염(tracheobronchitis)과 비성호흡(snuffles), 켄넬코프(kennel cough) 등의 질병을 일으킨다[ 1 , 2 ]. (ekjm.org)
  • In dogs, Bordetella are known as a component of kennel cough and they are also responsible for respiratory tract diseases in cats, although coughing is not a characteristic symptom in cats. (laboklin.com)
  • While Bordetella-induced kennel cough is classically thought of as causing only relatively mild disease, more severe disease may be seen, especially in a crowded shelter or boarding facility where stress and a high load of secondary pathogens provide a synergistic effect. (treatmentforkennelcough.com)
  • B. bronchiseptica causes several diseases in other mammals, including kennel cough and atrophic rhinitis in dogs and pigs, respectively. (wikipedia.org)
  • Cats infected with B. bronchiseptica have been seen with tracheobronchitis, conjunctivitis, and rhinitis (upper respiratory tract infection - URI), mandibular lymphadenopathy, and pneumonia. (wikipedia.org)
  • Bordetella bronchiseptica pneumonia. (bmj.com)
  • Lorenzo-Pajuelo B, Villanueva JL, Rodríguez-Cuesta J, Vergara-Irigaray N, Bernabeu-Wittel M, Garcia-Curiel A, de Tejada GM (2002) Cavitary pneumonia in an AIDS patient caused by an unusual Bordetella bronchiseptica variant producing reduced amounts of pertactin and other major antigens. (springer.com)
  • DISEASE SIGNS: A wide range of respiratory signs has been associated with B bronchiseptica infection, from a mild illness with fever, coughing, sneezing, ocular discharge and lymphadenopathy to severe pneumonia with dyspnoea, cyanosis and death. (uzh.ch)
  • We present a rare case of B. bronchiseptica pneumonia in a patient with lung cancer. (biomedcentral.com)
  • Bronchoscopy was performed and a diagnosis of B. bronchiseptica pneumonia was made. (biomedcentral.com)
  • We report a rare case of B.bronchiseptica pneumonia in a patient with lung cancer. (biomedcentral.com)
  • Bordetella bronchiseptica is an uncommon opportunistic infection in immune compromised hosts, causing pneumonia, bacteremia, UTIs, meningitis and endocarditis. (thefreedictionary.com)
  • Under conditions of natural exposure, Bordetella pneumonia can be expected to develop primarily due to defective host-patasite relationship. (meta.org)
  • The Bordetella bronchiseptica organism can cause pneumonia, septicemia, and peritonitis in humans with impaired immune systems. (ekjm.org)
  • Sixty-two human cases of Bordetella bronchiseptica have been published in the English literature, and 84 % hadof the cases were associated with pneumonia or bronchitis. (ekjm.org)
  • In the current study, we report a case of Bordetella bronchiseptica pneumonia diagnosed in an immunocompromised patient. (ekjm.org)
  • Bordetella bronchiseptica may lead to disseminated infection, cavitary pneumonia, and rarely fatal tracheobronchitis and sepsis. (kowsarpub.com)
  • It is reported that B. bronchiseptica causes disseminated infection, cavitary pneumonia, and rarely fatal tracheobronchitis or septicemia in these patients ( 4 ). (kowsarpub.com)
  • Here, we report a culture-proven case of B. bronchiseptica pneumonia in an immunocompromised host residing in a household with her dogs who had recently received live-attenuated, intranasal B. bronchiseptica vaccinations. (elsevier.com)
  • Gisel, JJ, Brumble, LM & Johnson, MM 2010, ' Bordetella bronchiseptica pneumonia in a kidney-pancreas transplant patient after exposure to recently vaccinated dogs: Case report ', Transplant Infectious Disease , vol. 12, no. 1, pp. 73-76. (elsevier.com)
  • Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. (nih.gov)
  • Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are closely related Gram-negative beta-proteobacteria that colonize the respiratory tracts of mammals. (nih.gov)
  • Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes. (asm.org)
  • Bordetella pertussis , Bordetella parapertussis and Bordetella bronchiseptica . (sanger.ac.uk)
  • The sequences and analysis are described in: Parkhill et al (2003) Comparative analysis of the genome sequences of Bordetella pertussis , Bordetella parapertussis and Bordetella bronchiseptica . (sanger.ac.uk)
  • PP6, a representative of the first group, recognizes an epitope shared by smooth-type Bordetella parapertussis and Bordetella bronchiseptica lipopolysaccharides (LPS). (microbiologyresearch.org)
  • In rabbits, B. bronchiseptica is often found in the nasal tract. (wikipedia.org)
  • B. bronchiseptica often co-infects the nasal passage at the same time. (wikipedia.org)
  • 1) (2) Clinical signs associated with B. bronchiseptica infection may include fever sneezing nasal discharge coughing and submandibular lymphadenopathy. (medi-vet.com)
  • Brockmeier SL (2004) Prior infection with Bordetella bronchiseptica increases nasal colonization by Haemophilus parasuis in swine. (springer.com)
  • Early after the intranasal instillation of Bordetella bronchiseptica into mice, not only are mature dendritic leukocytes recovered from lung parenchyma and bronchoalveolar lavage fluid but their numbers are also increased in the mediastinal lymph nodes and the nasal mucosa-associated lymphoid tissue. (pasteur.fr)
  • Parallel examination of specimens from the nasal cavities of 219 pigs in the field in southern England confirmed that this medium was better than hitherto recommended for the detection of B bronchiseptica. (meta.org)
  • In 2- to 3-week-old piglets, both B. bronchiseptica DNT and P. multocida DNT produced nasal turbinate lesions with similar severity, characterized by damage of the cilia, epithelial metaplasia, intensive proliferation of osteoblasts, regressive changes, and diffuse osteocytic osteolysis. (elsevier.com)
  • In 7- to 12-week-old piglets, treatment with B. bronchiseptica DNT failed to produce progressive changes in the nasal turbinates. (elsevier.com)
  • The viability of four strains of Bordetella bronchiseptica, two strains of B. pertussis and one strain of B. parapertussis exposed to hyperimmune and pre-colostrum porcine serum was examined. (nih.gov)
  • Viable cell numbers (cfu/ml) of the B. pertussis strains and a rough strain of B. bronchiseptica (CSU-P-1) decreased by 99% and 99.99%, respectively, after exposure for 1 h to porcine hyperimmune serum. (nih.gov)
  • In contrast, smooth B. bronchiseptica strains and the B. parapertussis strain showed no significant decrease in viable cell numbers after the same treatment. (nih.gov)
  • B. bronchiseptica strain CSU-P-1 also showed a 99% decrease in viable cell numbers after exposure to pre-colostrum porcine serum for 1 h whereas the other strains tested showed no decrease in viable numbers under the same conditions. (nih.gov)
  • Analysis of silver-stained SDS-PAGE profiles of lipopolysaccharide (LPS) extracted from the bacterial cells indicated that the smooth strains of B. bronchiseptica and the B. parapertussis strain possessed high mol. (nih.gov)
  • wt O-side chain-like material, whereas the B. pertussis strains and B. bronchiseptica strain CSU-P-1 did not. (nih.gov)
  • An insertion mutant of the wild-type B. bronchiseptica strain BB7865 which disrupted LPS biosynthesis was created and characterized (BB7865 pgm ). (asm.org)
  • Wild-type B. bronchiseptica 5376 attached very efficiently to dendritic cells, whereas the bvg mutant ATCC 10580, wild-type strain BB7865, and its spontaneous delta bvgS mutant BB7866 bound less efficiently. (asm.org)
  • Twenty-four vaccinated cats and 12 controls were challenged with a virulent strain of B. bronchiseptica six-months after vaccination, and two additional groups of vaccinates and controls were challenged one year after vaccination. (vin.com)
  • SUMMARY: R906, a plasmid derived from a wild strain of Bordetella bronchiseptica , was transferred to Escherichia coli k 12. (microbiologyresearch.org)
  • The Sanger Institute has been funded by the Wellcome Trust to sequence the genomes of Bordetella pertussis strain Tohama I, B. parapertussis strain 12822 and B. bronchiseptica strain RB50 in collaboration with Duncan Maskell and Andrew Preston of the Centre for Veterinary Science, Dept. of Clinical Veterinary medicine, The University of Cambridge. (sanger.ac.uk)
  • Mutants of B. bronchiseptica strain RB50 lacking sigE are more sensitive to high temperature, ethanol, and perturbation of the envelope by SDS-EDTA and certain β-lactam antibiotics. (biomedcentral.com)
  • In this work, the B. bronchiseptica strain to be used for RHINISENG® pre-clinical efficacy testing was characterized in an in vivo model to evaluate its ability to cause atrophic rhinitis lesions by its own. (hipra.com)
  • The organism would go through at least four more name changes before Moreno-Lopez founded and described the genus Bordetella (After the first man to isolate the pertussis-causing organism, Jules Bordet). (kenyon.edu)
  • B. bronchiseptica is of worldwide prevalence as it is a commensal organism of the respiratory tract in humans Footnote 4 . (canada.ca)
  • The in vitro interaction of B. bronchiseptica with dendritic cells reported here may be relevant to natural infections caused by this organism that lead to chronicity or an altered immune response. (asm.org)
  • Although the B. bronchiseptica vaccination is not mandatory for every dog, it may be recommended in dogs whose lifestyle increases their risk of exposure to this organism. (vetsecure.com)
  • 8. The pharmaceutical composition of claim 4 , wherein the cupredoxin peptide is from an organism selected from the group consisting of Pseudomonas aeruginosa, Alcaligenes faecalis, Achromobacter xylosoxidan, Bordetella bronchiseptica, Methylomonas sp. (google.com)
  • In dogs, B. bronchiseptica causes acute tracheobronchitis, which typically has a harsh, honking cough. (wikipedia.org)
  • M16492 B.bronchiseptica pertussis toxin pseudogene, complete cds. (atcc.org)
  • B. bronchiseptica does not express pertussis toxin, which is one of the characteristic virulence factors of B. pertussis. (sciencephoto.com)
  • Nucleotide sequencing of an EcoRI fragment of 5 kilobases comprising the regions homologous to the pertussis toxin genes shows that in this region, B. parapertussis and B. bronchiseptica are 98.5% and 96% homologous, respectively, to B. pertussis. (asm.org)
  • Several determinants of virulence expressed by B. pertussis , B. parapertussis , and B. bronchiseptica, such as filamentous hemagglutinin (FHA), pertactin (PRN), and fimbriae (Fim2 and Fim3), and toxins such as pertussis toxin (PT) and adenylate cyclise-hemolysin (AC-Hly) were not detected in B. petrii, except for an FHA-related adhesin with low similarity ( 22 ). (cdc.gov)
  • While its genome does encode complete pathways for biosynthesis of needed intermediates, Bordetella bronchiseptica and the genus Bordetella in general do not use sugars as a carbon source. (kenyon.edu)
  • Of the Bordetella genus, Bordetella bronchiseptica is the principle effector of respiratory disease in a wide range of mammals ( 16 ). (asm.org)
  • Bordetella is a genus of small (0.2 - 0.7 µm), Gram-negative coccobacilli of the phylum Proteobacteria. (wikipedia.org)
  • The Bordetella genus is named after Jules Bordet. (wikipedia.org)
  • B. bronchiseptica is credited as being the primary etiological component of tracheobronchitis in dogs from as early as 1910 ( 14 ) and is known to be associated with atrophic rhinitis, a common bronchial affliction of swine ( 40 ). (asm.org)
  • A novel virulent bacteriophage, vB_BbrM_PHB04, infecting Bordetella bronchiseptica was isolated from wastewater collected at a swine farm in China. (springer.com)
  • 1966 ). Pathology of experimental Bordetella bronchiseptica infection in swine: Atrophic rhinitis. (biologists.org)
  • Bordetella have been frequently detectable from lesioned lung material of swine as well as from the upper respiratory tracts of clinically intact animals. (meta.org)
  • B. bronchiseptica and Bordetella parapertussis do, however, produce an O-antigen of a single sugar polymer, consisting of 2,3-dideoxy-di- N -acetylgalactosaminuronic acid ( 4 , 13 ). (asm.org)
  • B. bronchiseptica adenylate cyclase-hemolysin was purified and was shown to be a major protective antigen against B. bronchiseptica infection. (pasteur.fr)
  • The phosphoglucomutase (PGM)-encoding gene of Bordetella bronchiseptica is required for lipopolysaccharide (LPS) biosynthesis. (asm.org)
  • Human infections associated with Bordetella bronchiseptica. (asm.org)
  • Iron acquisition by the gram-negative pathogens Bordetella bronchiseptica and Bordetella pertussis is thought to occur by hydroxamate siderophore-mediated transport as well as an apparently siderophore-independent process by which host transferrins bind to bacterial surface receptors. (ecu.edu)
  • pertussis and Bordetella holmesii and may be present in Bordetella bronchiseptica (6-10) (see Table 1 in the Data Supplement that accompanies the online version of this Technical Brief at http://www.clinchem.org/content/vol51/issue12). (thefreedictionary.com)
  • Bordetella bronchiseptica is an important bacterial component in canine infectious respiratory disease complex. (bmj.com)
  • Unlike most other Bordetella toxins, tracheal cytotoxin is expressed constitutively, being a normal product of the breakdown of the bacterial cell wall. (wikipedia.org)
  • Bordetella bronchiseptica is a minute, gram-negative rod-shaped coccobacilli about .5-1 micrometers in diameter and 5 micrometers in length. (kenyon.edu)
  • B. bronchiseptica is a gram-negative coccobacillus frequently isolated in the upper respiratory tract of domestic animals and wild animals, e.g. voles, seals, rodents and captive koalas. (biomedcentral.com)
  • Bordetella bronchiseptica is a Gram negative, aerobic coccobacillus. (liverpool.ac.uk)
  • Bordetella pertussis, Bordetella parapertussis and Bb are closely-related Gram-negative coccobacilli that colonise the respiratory tracts of mammals. (abcdcatsvets.org)
  • Bordetella are small gram-negative bacilli which can move by means of flagella. (laboklin.com)
  • Bordetella bronchiseptica is an aerobic, Gram-negative pleomorphic coccobacillus. (kowsarpub.com)
  • B. bronchiseptica infections are mediated by the controlled expression of a number of virulence factors, such as the adhesin filamentous hemagglutinin ( 10 ) and the toxins adenylate cyclase hemolysin and dermonecrotic toxin ( 7 , 50 ). (asm.org)
  • We studied the biochemical mechanism of morphological changes in cells treated with Bordetella dermonecrotizing toxin (DNT). (biologists.org)
  • 1988 ). Contractile action of heat-labile toxin of Bordetella parapertussis on aortic smooth muscle of pigs. (biologists.org)
  • 1989 ). Purification and characterization of Bordetella bronchiseptica dermonecrotic toxin. (biologists.org)
  • Humans are not natural carriers of B. bronchiseptica, which typically infects the respiratory tracts of smaller mammals (cats, dogs, rabbits, etc. (wikipedia.org)
  • It has also had its genome sequenced, primarily to derive data in comparison to its relative Bordetella pertussis, which causes whooping cough in humans. (kenyon.edu)
  • Humans are not natural carriers of B. bronchiseptica. (sciencephoto.com)
  • From this review we conclude that B. bronchiseptica has been rarely isolated from humans despite their considerable exposure to animal sources. (asm.org)
  • Evidence suggests that B. bronchiseptica may be rarely encountered as a commensal or colonizer of the respiratory tract of humans and rarely in association with infection. (asm.org)
  • B. bronchiseptica infection can be transmitted to humans from infected animals by aerosols carrying the infectious agent Footnote 6 , Footnote 9 , Footnote 10 . (canada.ca)
  • However, B. bronchiseptica only rarely infects humans ( 18 , 46 , 54 ). (asm.org)
  • Bordetella bronchiseptica ( B.bronchiseptica ) is a frequent cause of respiratory infections in animals but rarely causes serious infection in humans. (biomedcentral.com)
  • Bordetella bronchiseptica produces respiratory disease primarily in mammals including humans. (conicet.gov.ar)
  • Bordetella bronchiseptica rarely infect humans. (kowsarpub.com)
  • In humans, B. bronchiseptica infection is not common ( 2 ). (kowsarpub.com)
  • B. bronchiseptica rarely infects healthy humans, though disease in immunocompromised patients has been reported. (wikipedia.org)
  • Nobivac Feline-Bb is for vaccination of healthy kittens and cats for prevention of disease caused by B. bronchiseptica. (medi-vet.com)
  • Studies to evaluate the onset of immunity have demonstrated protection against B. bronchiseptica 72 hours after vaccination in 8 week old kittens. (medi-vet.com)
  • Vaccination against upper respiratory infections caused by Bordetella in cats. (tscpets.com)
  • Seven days after vaccination, the three groups were challenged with virulent Bordetella bronchiseptica via aerosolisation. (bmj.com)
  • The study demonstrated that vaccination with either Recombitek® Oral Bordetella or Nobivac® Intra-Trac 3 is effective in preventing disease seven days after vaccination when compared with dogs vaccinated with a placebo. (bmj.com)
  • 1 2 To date, there are injectable, oral and intranasal monovalent and combination vaccines available for vaccination of dogs to reduce or avoid the clinical signs of infection with B bronchiseptica . (bmj.com)
  • Thirty-one days prior to vaccination, all dogs were screened and determined to be serologically negative for antibodies to B bronchiseptica and to be negative for the presence of B bronchiseptica by tracheal culture. (bmj.com)
  • While not considered to be core, Bordetella vaccination may be recommended for dogs whose lifestyle places them at greater risk of contracting the disease. (vetstreet.com)
  • For vaccination of healthy, susceptible dogs and puppies as an aid in the prevention of Canine Upper Respiratory Infection (Canine Cough) caused by canine parainfluenza and Bordetella bronchiseptica . (medi-vet.com)
  • Vaccination can protect your dog from illness associated with Bordetella. (vetstreet.com)
  • Vaccination can protect your dog from illness associated with Bordetella, particularly if your dog frequents kennels, groomers, dog shows, or dog sporting events. (vetstreet.com)
  • Further investigation revealed that the patient's dogs had recently received a live-attenuated B. bronchiseptica intranasal vaccination. (elsevier.com)
  • However studies have shown that B. bronchiseptica may be the sole infectious agent in feline URI. (medi-vet.com)
  • Signs of canine infectious tracheobronchitis typically develop 2 to 14 days after exposure to B. bronchiseptica . (vetsecure.com)
  • Also, kennel conditions (such as group housing) can make it easier to spread infectious organisms, such as B. bronchiseptica . (vetsecure.com)
  • B. bronchiseptica strains are usually resistant to streptomycin Footnote 2 , primary penicillins such as penicillin G and ampicillin Footnote 2 , miocycline Footnote 2 , erythromycin Footnote 6 , ceftriaxone Footnote 10 . (canada.ca)
  • Functional assays for PGM revealed that enzyme activity is expressed in both bvg -positive and bvg -negative strains of B. bronchiseptica and is substantially reduced in BB7865 pgm . (asm.org)
  • It has recently been stated that the LPS of some strains of B. bronchiseptica is regulated by the bvg system ( 48 ). (asm.org)
  • However, all tested B. bronchiseptica strains were able to invade dendritic cells and survive intracellularly for at least 72 h. (asm.org)
  • The Sanger Institute has completed a project to sequence further strains within the Bordetella bronchiseptica complex to investigate the evolutionary history and host tropism differences within this group of organsims. (sanger.ac.uk)
  • Ferry also isolated it later (1912-1913) from the respiratory tracts of guinea pigs, monkeys, and other animals and subsequently changed the name to Bacillus bronchiseptica. (kenyon.edu)
  • 1940 ). The production of pertussis antitoxin in rabbits and the neutralization of pertussis, parapertussis and bronchiseptica toxins. (biologists.org)
  • Because of its toxins, B. bronchiseptica particularly damages the cilia-bearing cells of the respiratory mucosa and it can persist in the respiratory tract for up to three months. (laboklin.com)
  • The expression of many Bordetella adhesins and toxins is controlled by the two-component regulatory system BvgAS. (wikipedia.org)
  • Mixed infection with B. bronchiseptica and P. multocida leads to growth inhibition of pigs , resulting in significant economic loss. (bvsalud.org)
  • Several studies, some comparative, have evaluated the efficacy of these vaccines against B bronchiseptica challenge with varying results. (bmj.com)
  • 7 Injectable Bordetella vaccines also have a longer onset to protection since they require two doses separated by a few weeks to initiate immunity. (bmj.com)
  • This report expands the spectrum of immunocompromised hosts to include renal-pancreas transplant patients who have developed infection from B. bronchiseptica, while illustrating the risks associated with animal contacts and attenuated vaccines in the immunosuppressed population. (elsevier.com)
  • Both groups were challenged with wild-type Bordetella bronchiseptica and canine parainfluenza virus by the aerosol route 56 weeks after group 1 had been vaccinated, and at the same time six 10-week-old SPF puppies from the same source (group 3) were also challenged. (bmj.com)
  • PMID: 11326023 ] On rare occasion, the B. bronchiseptica genome may contain a copy of this sequence. (loinc.org)
  • In this context we searched in B. bronchiseptica genome for putative glycosyltransferases. (conicet.gov.ar)
  • It is sensible to consider B bronchiseptica as a rare cause of zoonotic infections. (uzh.ch)
  • Bordetella bronchiseptica is a rare pulmonary infection, often associated with zoonotic transmission. (elsevier.com)
  • In veterinary medicine, B. bronchiseptica leads to a range of pathologies in different hosts. (wikipedia.org)
  • The BvgAS signal transduction system in Bordetella spp. (nih.gov)
  • Akerley BJ, Monack DM, Falkow S, Miller JF (1992) The bvgAS locus negatively controls motility and synthesis of flagella in Bordetella bronchiseptica . (springer.com)
  • Much of the work on transcriptional regulation during infection in B. bronchiseptica has focused on the BvgAS two-component system. (biomedcentral.com)
  • Much of what is known about this regulatory system is based on work with B. bronchiseptica, but BvgAS is present in B. pertussis, B. parapertussis and B. bronchiseptica and is responsible for phase variation or phenotypic modulation. (wikipedia.org)
  • The regulation of these virulence determinants is under the control of a two-component signal transduction system known as the Bordetella virulence gene ( bvg ) locus. (asm.org)
  • An in-frame deletion of bscN in B. bronchiseptica leads to decreased secretion of several proteins, decreased cytotoxicity towards cultured cell lines and a defect in causing tyrosine dephosphorylation of specific proteins in infected cells in vitro. (nih.gov)
  • This observation could be due to the fact that Bordetella bronchiseptica may persist intracellularly in the host as it was demonstrated in vitro. (nih.gov)
  • In this report, we determine that Bordetella bronchiseptica can form biofilms in vitro and that the generation of biofilm is maximal in the Bvgi phase. (mendeley.com)
  • In vitro assays using mouse spleen cells and flow cytometry revealed that B. bronchiseptica Ag induced high proliferation capability of lymphocytes , especially B lymphocytes , and the proliferating cells showed a significant response to interleukin (IL)-2. (bvsalud.org)
  • 1,9] Due to its effect on mammals such as domestic pets (cats and dogs) and lab animals, Bordetella bronchiseptica has been closely studied. (kenyon.edu)
  • Bordetella bronchiseptica typically infects the respiratory tracts of smaller mammals (cats, dogs, rabbits). (sciencephoto.com)
  • 3) Because B. bronchiseptica is transmitted by the aerosol route animals in close confinement such as in catteries boarding facilities hospitals or pet stores or cats from multi-cat households are at greatest risk for infection. (medi-vet.com)
  • Cats with severe B bronchiseptica infection require supportive therapy and intensive nursing care. (uzh.ch)
  • Cats should not be routinely vaccinated against B bronchiseptica (non-core), since the infection generally causes only a mild disease. (uzh.ch)
  • Bordetella bronchiseptica can also infect very young or immunosuppressed people, so those individuals should not be around dogs or cats that have bordetellosis. (thefreedictionary.com)
  • Empregou-se uma vacina preparada com B. bronchiseptica e P. multocida tipo D, toxigênica, para controlar a rinite atrófica em rebanho de 220 matrizes suínas. (bvsalud.org)
  • The authors emphasize that the DNT of B. bronchiseptica basically differs from that of P. multocida in biological properties, though there are certain similarities between the DNTs. (elsevier.com)
  • B. parapertussis can also cause whooping cough, and B. bronchiseptica causes chronic respiratory infections in a wide range of animals. (nih.gov)
  • Prolonged shedding of B. bronchiseptica can occur, after resolution of clinical signs. (vetstream.com)
  • While the clinical presentation can be quite variable, it is important to note that Bordetella bronchiseptica can be a cause of pulmonary exacerbations and can be difficult to eradicate. (elsevier.com)
  • The proliferation of Bordetella bronchiseptica-reactive spleen cells occurred during the acute phase of infection. (nih.gov)
  • B bronchiseptica is a rare but potentially serious zoonosis. (liverpool.ac.uk)
  • Here we investigate the role of one such gene, sigE, in stress survival and pathogenesis of Bordetella bronchiseptica . (biomedcentral.com)