Bone Substitutes: Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapatite, beta-tricalcium phosphate, and various other biomaterials. The bone substitutes as inert materials can be incorporated into surrounding tissue or gradually replaced by original tissue.Calcium Phosphates: Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.Bone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.Ceramics: Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed)Calcium Sulfate: A calcium salt that is used for a variety of purposes including: building materials, as a desiccant, in dentistry as an impression material, cast, or die, and in medicine for immobilizing casts and as a tablet excipient. It exists in various forms and states of hydration. Plaster of Paris is a mixture of powdered and heat-treated gypsum.Durapatite: The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.Bone Regeneration: Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.Apatites: A group of phosphate minerals that includes ten mineral species and has the general formula X5(YO4)3Z, where X is usually calcium or lead, Y is phosphorus or arsenic, and Z is chlorine, fluorine, or OH-. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Bone Transplantation: The grafting of bone from a donor site to a recipient site.Tooth Socket: A hollow part of the alveolar process of the MAXILLA or MANDIBLE where each tooth fits and is attached via the periodontal ligament.Biocompatible Materials: Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.Bone Remodeling: The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.Absorbable Implants: Implants constructed of materials designed to be absorbed by the body without producing an immune response. They are usually composed of plastics and are frequently used in orthopedics and orthodontics.Osseointegration: The growth action of bone tissue as it assimilates surgically implanted devices or prostheses to be used as either replacement parts (e.g., hip) or as anchors (e.g., endosseous dental implants).Bone Cements: Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.Porosity: Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.Bone Cysts: Benign unilocular lytic areas in the proximal end of a long bone with well defined and narrow endosteal margins. The cysts contain fluid and the cyst walls may contain some giant cells. Bone cysts usually occur in males between the ages 3-15 years.Hydroxyapatites: A group of compounds with the general formula M10(PO4)6(OH)2, where M is barium, strontium, or calcium. The compounds are the principal mineral in phosphorite deposits, biological tissue, human bones, and teeth. They are also used as an anticaking agent and polymer catalysts. (Grant & Hackh's Chemical Dictionary, 5th ed)Osteogenesis: The process of bone formation. Histogenesis of bone including ossification.Bone Density: The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.Solid-Phase Synthesis Techniques: Techniques used to synthesize chemicals using molecular substrates that are bound to a solid surface. Typically a series of reactions are conducted on the bound substrate that results in either the covalent attachment of specific moieties or the modification of existing function groups. These techniques offer an advantage to those involving solution reactions in that the substrate compound does not have to be isolated and purified between the reaction steps.Compressive Strength: The maximum compression a material can withstand without failure. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p427)Curettage: A scraping, usually of the interior of a cavity or tract, for removal of new growth or other abnormal tissue, or to obtain material for tissue diagnosis. It is performed with a curet (curette), a spoon-shaped instrument designed for that purpose. (From Stedman, 25th ed & Dorland, 27th ed)X-Ray Microtomography: X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.Materials Testing: The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.Oral Surgical Procedures, Preprosthetic: Surgery necessary for a denture to rest on a firm base, free from marked osseous protuberances or undercuts, and devoid of interfering muscle attachments, excess mucoperiosteum, hyperplasias, and fibrous or papillary growths.Bone Resorption: Bone loss due to osteoclastic activity.Alveolar Process: The thickest and spongiest part of the maxilla and mandible hollowed out into deep cavities for the teeth.Alveolar Ridge Augmentation: Preprosthetic surgery involving rib, cartilage, or iliac crest bone grafts, usually autologous, or synthetic implants for rebuilding the alveolar ridge.Nanocomposites: Nanometer-scale composite structures composed of organic molecules intimately incorporated with inorganic molecules. (Glossary of Biotechnology and Nanobiotechology Terms, 4th ed)Bone Marrow: The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.Polyesters: Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours.Tissue Scaffolds: Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.Tooth Extraction: The surgical removal of a tooth. (Dorland, 28th ed)Spinal Fusion: Operative immobilization or ankylosis of two or more vertebrae by fusion of the vertebral bodies with a short bone graft or often with diskectomy or laminectomy. (From Blauvelt & Nelson, A Manual of Orthopaedic Terminology, 5th ed, p236; Dorland, 28th ed)Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Bone Marrow Cells: Cells contained in the bone marrow including fat cells (see ADIPOCYTES); STROMAL CELLS; MEGAKARYOCYTES; and the immediate precursors of most blood cells.Tissue Engineering: Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.Bone Development: The growth and development of bones from fetus to adult. It includes two principal mechanisms of bone growth: growth in length of long bones at the epiphyseal cartilages and growth in thickness by depositing new bone (OSTEOGENESIS) with the actions of OSTEOBLASTS and OSTEOCLASTS.Tibia: The second longest bone of the skeleton. It is located on the medial side of the lower leg, articulating with the FIBULA laterally, the TALUS distally, and the FEMUR proximally.Osteoblasts: Bone-forming cells which secrete an EXTRACELLULAR MATRIX. HYDROXYAPATITE crystals are then deposited into the matrix to form bone.Microscopy, Electron, Scanning: Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.Tibial FracturesBlood Substitutes: Substances that are used in place of blood, for example, as an alternative to BLOOD TRANSFUSIONS after blood loss to restore BLOOD VOLUME and oxygen-carrying capacity to the blood circulation, or to perfuse isolated organs.Bone Diseases: Diseases of BONES.Bioreactors: Tools or devices for generating products using the synthetic or chemical conversion capacity of a biological system. They can be classical fermentors, cell culture perfusion systems, or enzyme bioreactors. For production of proteins or enzymes, recombinant microorganisms such as bacteria, mammalian cells, or insect or plant cells are usually chosen.Bone Matrix: Extracellular substance of bone tissue consisting of COLLAGEN fibers, ground substance, and inorganic crystalline minerals and salts.Skin, Artificial: Synthetic material used for the treatment of burns and other conditions involving large-scale loss of skin. It often consists of an outer (epidermal) layer of silicone and an inner (dermal) layer of collagen and chondroitin 6-sulfate. The dermal layer elicits new growth and vascular invasion and the outer layer is later removed and replaced by a graft.Lumbar Vertebrae: VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.Bone Marrow Transplantation: The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.Wound Healing: Restoration of integrity to traumatized tissue.Stress, Mechanical: A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.Surface Properties: Characteristics or attributes of the outer boundaries of objects, including molecules.Bone Diseases, MetabolicFractures, Bone: Breaks in bones.Bone Morphogenetic Proteins: Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Bone Morphogenetic Protein 2: A potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor cells into OSTEOBLASTS.

Coating titanium implants with bioglass and with hydroxyapatite. A comparative study in sheep. (1/454)

This study compares the osteointegration of titanium implants coated with bioglass (Biovetro GSB formula) and with hydroxyapatite (HAP). Twenty-four bioglass-coated and 24 HAP-coated cylinders were implanted in the femoral diaphyses of sheep, and examined after 2, 4, 6, 8, 12, and 16 weeks. The HAP coating gave a stronger and earlier fixation to the bone than did bioglass. Bioglass formed a tissue interface which showed a macrophage reaction with little new bone formation activity. In contrast, HPA, showed intense new bone formation, with highly mineralised osseous trabeculae in the neighbourhood of the interface.  (+info)

Coral grafting supplemented with bone marrow. (2/454)

Limited success in regenerating large bone defects has been achieved by bridging them with osteoconductive materials. These substitutes lack the osteogenic and osteoinductive properties of bone autograft. A direct approach would be to stimulate osteogenesis in these biomaterials by the addition of fresh bone-marrow cells (BMC). We therefore created osteoperiosteal gaps 2 cm wide in the ulna of adult rabbits and either bridged them with coral alone (CC), coral supplemented with BMC, or left them empty. Coral was chosen as a scaffold because of its good biocompatibility and resorbability. In osteoperiosteal gaps bridged with coral only, the coral was invaded chiefly by fibrous tissue. It was insufficient to produce union after two months. In defects filled with coral and BMC an increase in osteogenesis was observed and the bone surface area was significantly higher compared with defects filled with coral alone. Bony union occurred in six out of six defects filled with coral and BMC after two months. An increase in the resorption of coral was also observed, suggesting that resorbing cells or their progenitors were present in bone marrow and survived the grafting procedure. Our findings have shown that supplementation of coral with BMC increased both the resorption of material and osteogenesis in defects of a clinical significance.  (+info)

Osteoinductive bone graft substitutes. (3/454)

This review will summarize the major efforts currently underway to develop osteoinductive bone graft substitutes for minimally invasive spine fusions. The primary categories of substitute include purified bone growth factors, recombinant bone growth factors, and growth factors delivered by gene therapy approaches. Clinical trials are underway for the purified and recombinant bone growth factors and pre-clinical studies have yielded promising results for a variety of gene therapy techniques for generating bone.  (+info)

Hydroxyapatite coated with heaptocyte growth factor (HGF) stimulates human osteoblasts in vitro. (4/454)

We have studied in vitro the effect of a hydroxyapatite (HA) tricalcium phosphate material coated with hepatocyte growth factor (HA-HGF) on cell growth, collagen synthesis and secretion of metalloproteinases (MMPs) by human osteoblasts. Cell proliferation was stimulated when osteoblasts were incubated with untreated HA and was further increased after exposure to HA-HGF. The uptake of [3H]-proline was increased after treatment with HA. When osteoblasts were exposed to HA-HGF, collagen synthesis was increased with respect to HA. The secretion of MMPs in control cells was undetectable, but in HA and HA-HGF cells MMP 2 and MMP 9 were clearly synthesised. Our results suggest that HA can promote osteoblast activity and that HGF can further increase its bioactivity.  (+info)

Porous apatite-wollastonite glass-ceramic as an intramedullary plug. (5/454)

We evaluated the efficacy and biocompatibility of porous apatite-wollastonite glass ceramic (AW-GC) as an intramedullary plug in total hip replacement (THR) for up to two years in 22 adult beagle dogs. Cylindrical porous AW-GC rods (70% porosity, mean pore size 200 microm) were prepared. Four dogs were killed at 1, 3, 6 and 12 months each and six at 24 months after implantation. Radiological evaluation confirmed the efficacy of porous AW-CG as an intramedullary plug. Histological evaluation showed osteoconduction at one month and resorption of the porous AW-GC, which was replaced by newly-formed bone, at 24 months. Our findings indicate that porous AW-GC can be used clinically as an intramedullary plug in THR.  (+info)

High density polyetherurethane foam as a fragmentation and radiographic surrogate for cortical bone. (6/454)

BACKGROUND: Although one of the most important factors in predicting outcome of articular fracture, the comminution of the fracture is only subjectively assessed. To facilitate development of objective, quantitative measures of comminution phenomena, there is need for a bone fragmentation surrogate. METHODS: Laboratory investigation was undertaken to develop and characterize a novel synthetic material capable of emulating the fragmentation and radiographic behavior of human cortical bone. RESULT: Screening tests performed with a drop tower apparatus identified high-density polyetherurethane foam as having suitable fragmentation properties. The material's impact behavior and its quasi-static mechanical properties are here described. Dispersal of barium sulfate (BaSO4) in the resin achieved radio-density closely resembling that of bone, without detectably altering mechanical behavior. The surrogate material's ultimate strength, elastic modulus, and quasi-static toughness are within an order of magnitude of those of mammalian cortical bone. The spectrum of comminution patterns produced by this material when impacted with varying amounts of energy is very comparable to the spectrum of bone fragment comminution seen clinically. CONCLUSIONS: A novel high-density polyetherurethane foam, when subjected to impact loading, sustains comminuted fracture in a manner strikingly similar to cortical bone. Moreover, since the material also can be doped with radio-opacifier so as to closely emulate bone's radiographic signature, it opens many new possibilities for CT-based systematic study of comminution phenomena.  (+info)

A bone replaceable artificial bone substitute: morphological and physiochemical characterizations. (7/454)

A composite material consisting of carbonate apatite (CAp) and type I atelocollagen (AtCol) (88/12 in wt/wt%) was designed for use as an artificial bone substitute. CAp was synthesized at 58 degrees C by a solution-precipitation method and then heated at either 980 degrees C or 1,200 degrees C. In this study, type I AtCol was purified from bovine tail skins. A CAp-AtCol mixture was prepared by centirfugation and condensed into composite rods or disks. The scanning electron-microscopic (SEM) characterization indicated that the CAp synthesized at 58 degrees C displayed a crystallinity similar to that of natural bone and had a high porosity (mean pore size: about 3-10 microns in diameter). SEM also revealed that the CAp heated at 980 degrees C was more porous than that sintered at 1,200 degrees C, and the 1,200 degrees C-heated particles were more uniformly encapsulated by the AtCol fibers than the 980 degrees C-heated ones. A Fourier transformed-infrared spectroscopic analysis showed that the bands characteristic of carbonate ions were clearly observed in the 58 degrees C-synthesized CAp. To enhance the intramolecular cross-linking between the collagen molecules, CAp-AtCol composites were irradiated by ultraviolet (UV) ray (wave length 254 nm) for 4 hours or vacuum-dried at 150 degrees C for 2 hours. Compared to the non cross-linked composites, the UV-irradiated or dehydrothermally cross-linked composites showed significantly (p < 0.05) low collagen degradation and swelling ratio. Preliminary mechanical data demonstrated that the compressive strengths of the CAp-AtCol composites were higher than the values reported for bone.  (+info)

Spinal fusions: bone and bone substitutes. (8/454)

Vertebral arthrodesis is one of the most commonly performed, yet incompletely understood, procedures in spinal surgery. Despite major progress in internal fixation techniques, the high rate of nonunions indicates that physiologic, biologic and molecular events that are crucial to this process are not well known. This article will analyze the general biology of bone regeneration, and particularly discuss the properties and use of various bone graft materials and graft substitutes.  (+info)

*Goulash

Substitute beef bones for the meat and add vegetables. Also called Hamisgulyás, (Fake Goulash) ...

*Mathys Medical

"Mathys bone graft substitutes". Mathys Ltd Bettlach. "Mathys Sports medicine". Mathys AG Bettlach. Retrieved 2013-11-05. " ... knee and shoulder as well as biomaterials for surgical treatment of bone defects (bone grafting) With an innovative implant for ... Mathys begins to develop and produce implants and instruments for bone surgery and orthopaedics. Starting 1960, the first ... products for bone fracture treatment were merchandised after the guidelines of the Arbeitsgemeinschaft für Osteosynthesefragen ...

*Latin American childlore

But also 'children are clever at inventing substitutes. They make them of bones, stones, sticks, and rags. Their make-believe ...

*Brass quintet

In some pieces, the horn is replaced by an additional trombone. Some quintets substitute a euphonium for the trombone part. ... one trombone or euphonium/baritone horn, and one tuba or bass trombone. However, musicians in a brass quintet often play ... the range and style of many pieces lend themselves to being played with bass trombone as the lowest-pitched instrument. ...

*Goulash

Substitute beef bones for the meat and add vegetables. Also called Hamisgulyás, (Fake Goulash) Bean Gulyás. Omit the potatoes ...

*Cranioplasty

The metallic bone substitutes have largely been replaced by modern plastics. Poly(methyl methacrylate) (PMMA) was introduced in ... The first bone graft was recorded by Job Janszoon van Meekeren, who in 1668 noted that canine bone was used to repair a cranial ... The next advance in cranioplasty was the experimental groundwork in bone grafting, performed in the late 19th century. The use ... Research in cranioplasty is now directed at improving the ability of the host to regenerate bone. As modern day trephiners, ...

*Chronic periodontitis

Bone substitutes may be associated with less gingival recession than EMD." Systemic antibiotics such as amoxicillin or ... and bone-sparing agents. A systematic review". Ann. Periodontol. 8 (1): 12-37. doi:10.1902/annals.2003.8.1.12. PMID 14971246. ... which results in bone and soft tissue destruction. In response to endotoxin derived from periodontal pathogens, several ... Gingival inflammation and bone destruction are often painless. Patients sometimes assume that painless bleeding after teeth ...

*Borscht

Marrow bones are considered best for the bone stock. Meat stock is usually cooked for about two hours, whereas bone stock takes ... Parsnip may be used as a substitute for parsley root, and tomato paste is often used as well as or instead of fresh tomatoes.[ ... Borscht based on bone stock may be served Old Polish style, with marrow from the bones.[54] ... Meat and bones are usually removed afterwards and the meat is only added back into the soup about 10-15 minutes before the ...

*Steerhorn

Today, many orchestras substitute the trombone or bass trombone. The Solti recording, the Golden Ring, had a steerhorn ...

*Wawasee

He sometimes substituted a fish bone for the ring. Turkey Lake became Lake Wawasee in his honor. Wawasee is the namesake of ...

*Joshpara

Mutton can be substituted with beef, or even with chicken. The Broth is made from mutton bones; the ground meat is prepared ... with its pronunciation altering to pel'meni and chicken broth being used as a substitute for the yogurt broth. One of the ...

*2,6-Lutidine

It was isolated from the basic fraction of coal tar and from bone oil. It has been detected in waste water from oil shale ... It is one of several dimethyl-substituted derivative of pyridine. It is a colorless liquid with mildly basic properties and a ...

*Ebrahim Maka

While batting he had two bones of his right hand broken by fast bowler Frank King. Vijay Manjrekar substituted for him and ...

*Dentistry

He suggested that substitutes could be made from carved blocks of ivory or bone. He also introduced dental braces, although ...

*3D bioprinting

... including soft tissue and bone. These constituents can act as future substitutes, even improvements, for the original body ... Thomas D.J. "Using 3D-Bioprinting for Artificial Bones > ENGINEERING.com". www.engineering.com. Retrieved 2016-07-01. "Trail- ... Nakashima, Yasuharu; Okazak, Ken; Nakayama, Koichiet; Okada, Seiji; Mizu-uchi, Hideki (January 2017). "Bone and Joint Diseases ... a research team at Swansea University in the UK is using bioprinting technology to produce soft tissues and artificial bones ...

*Baleen

Like other bone materials, this often functioned as a substitute for ivory. Depending on the species, a baleen plate can be 0.5 ... It is not to be confused (but often is) with whale bone or whale's bone meaning the actual bones of whales, used in carving, ... including a buttress of bone in the upper jaw beneath the eyes, and loose lower jaw bones at the chin. Baleen is believed to ... John Henry Devereux South Carolina architect who used whale jaw bones to adorn the largest mansion on Sullivan's Island Fudge, ...

*Strontium

Its presence in bones can cause bone cancer, cancer of nearby tissues, and leukemia. The 1986 Chernobyl nuclear accident ... In biological systems, calcium is substituted in a small extent by strontium. In the human body, most of the absorbed strontium ... Cabrera, Walter E.; Schrooten, Iris; De Broe, Marc E.; d'Haese, Patrick C. (1999). "Strontium and Bone". Journal of Bone and ... 89Sr is the active ingredient in Metastron, a radiopharmaceutical used for bone pain secondary to metastatic bone cancer. The ...

*Early Cuban bands

The ophicleide (ophicleide) was a sort of bass bugle with keys, invented in 1817; the t-bone would be a valve trombone. They ... Probably it had started with an ophicleide, and later substituted the saxophone. They included a piano by 1929. The group ... Its members at the start of the 20th century included the following: Perico Rojas (trombone); Patricio Valdés and Andrés Rojas ... The orchestra was a típica, with cornet, trombone, ophicleide, two clarinets, two violins, double bass, kettle drum, and güíro ...

*Isotopes of strontium

It causes health problems, as it substitutes for calcium in bone, preventing expulsion from the body. Because it is a long- ... Because strontium has an electron configuration similar to that of calcium, it readily substitutes for Ca in minerals. In ... 89Sr is an artificial radioisotope used in treatment of bone cancer. In circumstances where cancer patients have widespread and ...

*Duck as food

De-boned duck breast can be grilled like steak, usually leaving the skin and fat on. Internal organs such as heart and kidneys ... may also be eaten; the liver in particular is often used as a substitute for goose liver in foie gras. Duck is particularly ...

*Nanophase ceramic

This way as bone grows the substitute can diminish at a similar rate. Averback, Robert S. (May 21, 1992). "Nanophase Ceramics: ... Nano-hydroxyapatite is one nanophase ceramic that is used as a bone substitute. Nano grain size increases the bonding, growth, ... Bone and collagen have structures on the nanoscale. Nanomaterials can be manufactured to simulate these structures which is ... The surfaces of nanophase ceramics can also be modified to be porous allowing osteoblasts to create bone within the structure. ...

*Space habitat

NASA studies with chickens and plants have proven that this is an effective physiological substitute for gravity.[citation ... Long-term on-orbit studies have proven that zero gravity weakens bones and muscles, and upsets calcium metabolism and immune ...

*Borscht

... some of these components may be omitted or substituted for. The stock is typically made by boiling meat, bones, or both. Beef, ... Marrow bones are considered best for the bone stock. Meat stock is usually cooked for about two hours, whereas bone stock takes ... Borscht based on bone stock may be served Old Polish style, with marrow from the bones. Some kinds of the soup, such as Poltava ... Meat and bones are usually removed afterwards and the meat is only added back into the soup about 10-15 minutes before the ...

*Central Park Brass

For the 2008 season Douglas Lyons substituted for Cordell and Michael Seltzer for Albrecht. Arts Briefing - New York Times ... The members are David Spier trumpet, Arthur Murray trumpet, Angela Cordell French horn, Lisa Albrecht trombone, and Morris ...

*Lactagen

Most persons with LI avoid ingestion of milk and dairy products, while others substitute non-lactose-containing foods in their ... Barger-Lux and Heaney (August 1, 1994). "The role of calcium intake in preventing bone fragilty, hypertension and certain ... and low bone density. There is substantial evidence indicating that lactose intolerance is a major factor in limiting calcium ...

*Mark McHugh

McHugh made a substitute appearance against Monaghan in the 2014 National Football League Division 2 Final at Croke Park. Three ... McHugh did not play at minor level, what with the Leaving Certificate and a broken collar bone. He made his senior championship ... debut as a substitute against Down in Ballybofey in 2010. He was part of the 2011 team that won the Ulster Senior Football ...

*Catenin

Mice lacking plakoglobin have cell adhesion defects in many tissues, although β-catenin substitutes for plakoglobin at many ... Coluzzi F, Mandatori I, Mattia C (September 2011). "Emerging therapies in metastatic bone pain". Expert Opin Emerg Drugs. 16 (3 ...

*Jack Clark (television personality)

In 1988, Clark was diagnosed with bone cancer. He continued announcing for Wheel of Fortune for as long as he was able to up ... When Clark was a student at University of California, Berkeley (UC Berkeley), he began his career as a substitute radio ... When he was away, Charlie O'Donnell and Johnny Gilbert began filling in as substitute announcers. Clark died on July 21, 1988 ... he also occasionally substituted for host Allen Ludden). From there, he went on to host 100 Grand (1963) and Dealer's Choice ...
0091] FIGS. 12-16 show some results of testing of an embodiment of the fibrous bone graft material of the present disclosure on a mammal (specifically, in this case a rabbit.) In the testing, a bilateral distal femoral bone defect was created having a size of approximately 5 mm in diameter and 10 mm in length. In addition to an embodiment of the bone graft material of the disclosure, the testing was performed along with commercially available bone graft substitute, Products #1 and #2, in a comparison study. Product #1 is a silicate substituted bone graft material (ACTIFUSE® available from ApaTech, Inc. of Foxborough, Mass.) and Product #2 is a synthetic bone graft substitute (VITOSS®, available from Orthovita of Malvern, Pa.) In particular, FIG. 12 shows a series of radiographic images from testing performed on a mammal comparing the performance of an embodiment the bone graft material with Products 1 and 2 at 4 weeks, 6, weeks and 12 weeks. FIG. 13 shows another series of images from testing ...
No. of Report Pages: 126. Price (Single User Licence): $ 2900. Purchase the Synthetic Dental Bone Graft Substitute Market Report at: https://www.absolutereports.com/purchase/10555586 Several important topics included in the Synthetic Dental Bone Graft Substitute Industry research report are as follows:. • Overview of Synthetic Dental Bone Graft Substitute Industry. • Market Size (Value and Volume) analysis of Synthetic Dental Bone Graft Substitute Industry. • Synthetic Dental Bone Graft Substitute Industry Competition by Manufacturers, Type and Application. • Synthetic Dental Bone Graft Substitute Industry Major Regions Volume, Value and Sales Price Analysis. • Synthetic Dental Bone Graft Substitute Industry Technology and Development Trend. • Research Findings and Conclusion of Synthetic Dental Bone Graft Substitute Industry. To sum it up, the report concludes with an all-inclusive research result on the industry chain of Synthetic Dental Bone Graft Substitute Industry facilitating ...
Does anyone have information regarding defatting and dehydration of bone containing calcium sulfate type bone substitute materials (specifically Osteoset made by Wright Medical)? Will standard methods using ethanol and acetone preserve this calcium sulfate? We will run some samples through using our standard protocol, but I was thinking that others may have already had some experience with these bone substitute materials ...
The purpose of this investigation is to compare new bone formation through histomorphometric analysis following maxillary sinus augmentation using three different bone graft materials. Null Hypothesis is that there is no histomorphometric difference in new bone formation in maxillary sinuses augmented using three different materials; anorganic bovine bone graft (Bio-Oss), anorganic equine bone graft (Equimatrix) and mineralized bone allograft (OSSIF-i sem). Patients who require sinus augmentation prior to implant placement will be selected to participate in this study. All patients will be randomly placed into three groups according to bone graft materials that will be used. Group A (Control group,n=10): Maxillary sinus augmentation using anorganic bovine bone graft (Bio-Oss), Group B (Test group,n=10):Maxillary sinus augmentation using anorganic equine bone graft (Equimatrix), and Group C (Test group,n=10):Maxillary sinus augmentation using mineralized bone allograft (OSSIF-i sem). All the ...
A resorbable bone replacement material made of calcium phosphate particles of different phases which are embedded in an inventive-specific cross-linked collagen matrix. The goal is to form a non-brittle, bone replacement moulded body having a positive fit, i.e. having a shape which is anatomic and/or corresponds to the defect, which perfectly fills the bone defect and can be resorbed thereby. Said goal is achieved by producing the bone replacement material made of a mixture of calcium phosphate particles which is embedded in an inventive cross-linked collagen matrix. In particular, the collagen cross-linking is achieved by a Laccase-induced peptide cross-linking and suitable bridge molecules. Essentially substituted dihydroxyarmotes and/or substrates of the lignolytic polyphenoloxidases, such as Laccases, are suitable as bridge molecules. Also, monocyclic ortho-dihydroxyaromates, monocyclic para-dihydroxyaromates, bicyclic monohydroxyaromates, polycyclic monohydroxyaromates, bicyclic dihydroxyaromates,
A biologic artificial bone includes an artificial fiber material formed from a synthetic polymer with mechanical properties similar to type I collagen. A biocompatible liquid substance is impregnated in the fiber material that hardens and stiffens the fiber material. A bone substitute is impregnated in the hardened and stiffened fiber material forming an artificial bone composite. Vascular channels are formed in the artificial bone composite to facilitate in-growth of vessels and bone forming cells. The construction and methods achieve an artificial composite structure that is similar to natural bone with comparable properties.
Critical size bone defects and non-union fractions are still challenging to treat. Cell-loaded bone substitutes have shown improved bone ingrowth and bone formation. However, a lack of methods for homogenously colonizing scaffolds limits the maximum volume of bone grafts. Additionally, therapy robustness is impaired by heterogeneous cell populations after graft generation. Our aim was to establish a technology for generating grafts with a size of 10.5 mm in diameter and 25 mm of height, and thus for grafts suited for treatment of critical size bone defects. Therefore, a novel tailor-made bioreactor system was developed, allowing standardized flow conditions in a porous poly(L-lactide-co-caprolactone) material. Scaffolds were seeded with primary human mesenchymal stem cells derived from four different donors. In contrast to static experimental conditions, homogenous cell distributions were accomplished under dynamic culture. Additionally, culture in the bioreactor system allowed the induction of ...
There is disclosed a bone substitute material for medical use which satisfies all the requirements of (1) no histotoxicity, (2) osteoconductivity, (3) bone replacement capability, and (4) mechanical strength necessary for a bone reconstruction operation. The bone substitute material for medical use is predominantly composed of carbonate apatite and produced through the formation of carbonate apatite by contacting a block of calcium compound with a phosphate-containing solution, wherein the calcium compound block contains substantially no powders, and at least one of said calcium compound block and said phosphate solution contains a carbonate group, without any sintering. The block of calcium compound is preferably one prepared using an artificially synthesized calcium compound, most preferably a foamed calcium compound.
GBR is a technique used for the regeneration of lost alveolar bone by the help of a grafting material and a barrier membrane. The defect is filled with a bone graft material (allogeneic-, xenogeneic- or alloplastic bone substitute materials) that serves as a scaffold for ingrowth of bone forming cells (osteoconduction) and blood vessels, and prevents collapse of the overlying membrane and soft tissue. The membrane acts as a barrier agains ingrowth of fast proliferating connective tissue cells, hence, giving the bone forming cells time and space for the osseous regeneration of the defect. Moreover, the membrane stabilizes the bone graft material and prevents the migration of particles.
Disclosed herein is a bone graft applicator assembly including a specially designed applicator, attached to a reservoir of bone graft material, such that the graft material can be moved into the delivery portion while the tip of the delivery portion is in place. The instantly disclosed device allows for the collapse of the delivery tip so that the tip can be placed between vertebras or alternatively within any bony structure or implant where the placement of bone graft material would be desirable, and then expanded to allow the bone graft material to be placed between the vertebras or the like while maintaining the geometry of the space into which the bone graft material is being placed.
The objective of this study was to investigate the surface modification of a natural bone substitute, Bio-Oss, coated with a synthetic polymer poly- D,L-lactide (PLA), in order to improve cell growth. Bio-Oss is a natural bone substitute made of the mineralized portion of bovine bone. The material is used mainly to fill bone defects in periodontal and maxillofacial surgery and permit reossification. Poly-α-hydroxyacids such as polylactic acid are receiving an increasing attention due to their ability to retain a great quantity of water, good biocompatibility, low interfacial tension, and minimal mechanical and frictional irritation. All of these features are appealing from the perspective of bioenvironmental mimicking. The human osteosarcoma cell line SAOS-2 was added to the top of scaffolds uncoated or coated with PLA and incubated at 37◦C in 5%CO2 for 15 days. PLA-coated scaffolds improved cell growth. Polymer degradation behaviour, extraction and measurement of the extracellular matrix ...
TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents ...
Segments. The global bone graft substitute market has been segmented on the basis of type and application. Based on type, the market has been segmented as autograft, demineralized bone matrix, synthetic bone grafts, bone morphogenetic protein, and others. Based on the application, the market has been segmented as a spinal fusion, joint reconstruction, long bone, dental, foot & ankle, and others.. Browse Full Report Details @ https://www.marketresearchfuture.com/reports/bone-graft-substitutes-market. Regional analysis. The US accounts for the significant market share due to extensive use of medications and greater expenditure on health care. The fastest uptake of new technology and devices in the US is also an important driver of the global bone graft substitute market. The concentration of the major medical device manufacturers in the developed regions is also adding fuel to the market.. Europe is the second largest market due to a high disposable income and rising awareness regarding bone graft ...
A method for fabricating a substitute component for bone, including the processes of: provision of a chemical spray including at least three of calcium chloride, hydrogen phosphate, hydrogen carbonate and water to form a combined solution; reaction and precipitation of the combined solution onto a substrate; allowing the precipitated particles to form a porous structure on the substrate; applying substantially isostatic pressure to the porous structure to form a compressed structure; and (optional) providing one or more through-holes in the compressed structure to promote osteoinduction.
Because of their bioactive properties and chemical similarity to the inorganic component of bone, calcium phosphate (CaP) materials are widely used for bone regeneration. Six commercially available CaP bone substitutes (Bio-Oss, Actifuse, Bi-Ostetic, MBCP, Vitoss and chronOs) as well as two tricalcium phosph
Most bone augmentation procedures involve the use of bone grafts. An excellent choice for a bone graft is your own bone (Autogenous bone ). Bone harvested from the patients own body is the "gold standard" and often times has the most predictable results. This is described as the best type of graft because such bone is live with active cellular elements that enhance bone growth, whereas other types of grafts are devoid of any active cellular material. synthetic bone graft material. This most likely will come from the adjacent area where implant is being placed or from your chin or ramus (the back part of your lower jaw). If your dentist cannot get enough bone from these areas, he or she may need to get bone from your hip or shin bone (tibia) instead. If you dont like the idea of having bone removed from your body to be placed in your jaw, other excellent option which is commonly used is synthetic bone graft material. These bone graft substitutes do not require a second surgical site as does the ...
A strong, porous article useful as a bone substitute material. The article comprises a continuous strong framework structure having struts defining interstices which interconnect throughout the bulk volume, and may have ceramic or osteoconductive material occupying at least a portion of the same bulk volume as the framework structure. Either as a coating on the strong framework struts or between the framework struts and the ceramic or osteoconductive-osteoinductive materials is a resilient material which serves to distribute stresses within the article.
A strong, porous article useful as a bone substitute material. The article comprises a continuous strong framework structure having struts defining interstices which interconnect throughout the bulk v
chronOS® Bone Graft Substitute (BGS) is a synthetic β-tricalcium phosphate bone void filler which is radiopaque, resorbable and osteoconductive.
chronOS® Bone Graft Substitute (BGS) is a synthetic β-tricalcium phosphate bone void filler which is radiopaque, resorbable and osteoconductive.
An injectable bone mineral substitute material composition comprises an inorganic bone cement powder and a biologically compatible oil. The oil is an intermixture with the cement powder at a concentration of less than 10 wt % of the total weight of the composition in order to improve the rheology of the same. In a method of intermixing a powder of an implant material and a biologically compatible oil to a composition the oil is mixed with the powder of implant material at an elevated temperature.
Alongside the standard donor bone transfer, bone substitutes have established themselves, improved in quality and are being increasingly used in the surgical treatment of dysmorphic defects or defects following inflammation, tumor surgery or trauma, particularly in the last three decades. With the discussion about infectious disease transmission through tissue from bone banks, the use of donor bone has receded into the background. For this reason, suitable bone substitutes are being sought constantly. Implants of many different physical and chemical substance groups have been tested for their suitability as bone substitutes, but an ideal material has yet to be found. In animal experiment models and their clinical application in humans, various bone substitutes have been evaluated for the dynamic of the resulting bone formation using nuclear medical and radiological procedures and have been examined histologically for their value as functional bone substitutes. Compared to autogenous bone grafts, ...
Bone substitutes with enhanced biological activity are required for the replacement, repair and regeneration of skeletal tissue. This project aims to design a bioreactor for stem cell expansion on novel hydroxyapatite bone substitute materials designed for accelerated osseointegration of implants. Mathematical modelling has been used alongside physical and biological experiments to define the bioreactor environment. Initial experiments have been carried out using the osteogenic cell line MG63 seeded on both porous particles1,2 and disks of HA/TCP (hydroxyapatite/tricalcium phosphate). A purpose built flow chamber has been developed to study the shear stress required to detach cells from the HA/TCP surfaces. The CFD package FLUENT has been used to model the fluid dynamics in a fluidised bed bioreactor to investigate the distributor design, aspect ratio and flowrates of the system. Experiments have been carried out to investigate the fluidisation behaviour of the HA/TCP particles. Particles (2-4 ...
Bone & joint health is important at any age. Shop the extensive selection of supplements for natural bone and joint from iHerb for the best value and selection!
Bone & joint health is important at any age. Shop the extensive selection of supplements for natural bone and joint from iHerb for the best value and selection!
Costamagno, Sandrine., 1999: Coudoulous II taphonomy of a natural trap Natural bone accumulations and the interpretation of Middle Palaeolithic archaeofaunas Coudoulous II taphonomie dun aven-piege Contribution des accumulations dorigine naturelle a linterpretation des archeofaunes du Paleolithique moyen
The Straumann® Bone Block Fixation Set is a Guided Bone Regeneration system used for the stabilization and fixation of bone transplants, blocks and struts in oral cavities. The bone transplant fixation technique enables the placement of implants at positions where formerly an implant insertion was not applicable. In cases where the bone defect at the resorbed alveolar crest is too extensive for regeneration by using bone substitute material and barrier membranes only, the bone substitute and barrier membrane can be combined with the fixation of a bone block (maxgraft® bonebuilder, maxgraft® granules & blocks ...
...NEW YORK Dec. 14 2010 /- Reportlinker.com announces tha...a href http://www.reportlinker.com/p0339837/European-Markets-for-Den...a href http://www.reportlinker.com/p0339837/European-Markets-for-Den...In 2010 the total European markets for dental bone graft substitutes ...,Reportlinker,Adds,European,Markets,for,Dental,Bone,Graft,Substitutes,,Dental,Membranes,and,Tissue,Engineering,2011,medicine,advanced medical technology,medical laboratory technology,medical device technology,latest medical technology,Health
AbeBooks.com: Bone Graft Substitutes (9780803133563) by Cato T. Laurencin and a great selection of similar New, Used and Collectible Books available now at great prices.
A new type of artificial bone shaped with a 3-D printer can repair deformed bones and help heal some spine, skull and jaw injuries, researchers say in a new report printed in the journal Science Translational...
Dental Update is the leading dental journal for CPD (Continuing Professional Development) and education. Dental Update gives verifiable CPD and PDP management
Purpose: To evaluate bone graft substitutes used in spine fusion surgery and determine the feasibility of studying the use of adult stem cells. Hypothesis: Using a well designed, randomized clinical trial to compare bone graft substitutes used in spine fusion surgery will help determine the best alternative to autologous bone graft. Design: Retrospective data on two bone graft substitutes will be evaluated. A protocol for studying stem cells in spine fusion will be drafted and the feasibility of implementing the trial will be analyzed. Results: It is difficult to design a randomized clinical trial to investigate a new surgical technique. The lack of standardization among spine surgeons makes it difficult to control for confounding variables.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Conditions for spontaneous bone healing after trauma or orthopedic surgery are not always ideal. Even with the efficacy of modern internal fixation and spinal fusion techniques, factors such as poor vascularity, malnutrition, and substantial bone or soft tissue loss can impede effective bone growth. As a result, the market for bone grafts and substitutes has emerged and exploded. Growing orthopedic and spinal procedure volumes, as well as increasing adoption of synthetic bone substitutes, are primarily driving the expansion of the bone grafts and substitutes market in the forecast period. However, high product cost is a demanding obstacle to be overcome. This report focuses on the market outlook for bone graft and substitute products in North America (Canada, Mexico, and US). The analysis discusses the major drivers and barriers of adoption, and provides an in-depth understanding of the future outlook for this market by segment and geography.. Key Questions Answered What is the current and ...
Bone grafting is a surgical procedure that replaces missing bone in order to repair bone fractures that are extremely complex.. Bone generally has the ability to regenerate completely but requires a very small fracture space or some sort of scaffold to do so. Bone grafts may be autologous (bone harvested from the patients own body, often from the iliac crest), allograft (cadaveric bone usually obtained from a bone bank), or synthetic (often made of hydroxyapatite or other naturally occurring and biocompatible substances) with similar mechanical properties to bone. Most bone grafts are expected to be reabsorbed and replaced as the natural bone heals over a few months time.. The principles involved in successful bone grafts include osteoconduction (guiding the reparative growth of the natural bone), osteoinduction (encouraging undifferentiated cells to become active osteoblasts), and osteogenesis (living bone cells in the graft material contribute to bone remodeling). Osteogenesis only occurs ...
Regenics bone regeneration synthetic materials regenics bone regeneration help regeneration of bone synthetic materials materials regenics synthetic
PURPOSE: The aim of this study was to test whether or not implants associated with bone regeneration show the same survival and success rates as implants placed in native bone in patients requiring both forms of therapy. MATERIAL AND METHODS: Thirty-four patients (median age of 60.3 years, range 18-77.7 years) had been treated 5 years before the follow-up examination. Machined screw-type implants were inserted following one of two surgical procedures: (1) simultaneously with a guided bone regeneration (GBR) procedure, which involved grafting with xenogenic bone substitute material, autogenous bone or a mixture of the two and defect covering with a bio-absorbable collagen membrane (test) and (2) standard implantation procedure without bone regeneration (control). For data recording, one test and one control implant from each patient were assessed. Examination included measurements of plaque control record (PCR), probing pocket depth (PPD), bleeding on probing (BOP), width of keratinized mucosa ...
The speed of degradation of Syn Oss = Rate of bone formation Degrades fully within 6 - 12 months, depending upon regeneration dynamics of the patient.. Syn Oss is indicated for filling of mostly non-stressed, multiple bone defects of the skeleton. The augmentation site should be free of inflamation, soft tissue, granulation tissue & infection. Indications include : Post extraction ridge ...
Bone grafting is a surgical procedure that replaces missing bone in order to repair bone fractures that are extremely complex, pose a significant health risk to the patient, or fail to heal properly. Some kind of small or acute fractures can be cured but risky for large fractures like compound fractures. Bone generally has the ability to regenerate completely but requires a very small fracture space or some sort of scaffold to do so. Bone grafts may be autologous (bone harvested from the patients own body, often from the iliac crest), allograft (cadaveric bone usually obtained from a bone bank), or synthetic (often made of hydroxyapatite or other naturally occurring and biocompatible substances) with similar mechanical properties to bone. Most bone grafts are expected to be reabsorbed and replaced as the natural bone heals over a few months time. The principles involved in successful bone grafts include osteoconduction (guiding the reparative growth of the natural bone), osteoinduction ...
Find orthopedics stem cell bone substitute studies here. Mississsippi Stem Cell Therapy Center promotes stem cell therapy and regenerative medicine.
Is this the study that was awarded a prize last year for being the most cited study with Geistlich biomaterials? Prof. Lindhe: Yes it is. The funny thing is that we mainly conducted it to investigate the soft tissues. Our focus was: is there any difference regarding epithelium cells, connective tissue cells, etc., between the soft tissues above bone and the soft tissues above a bone substitute material? But the reason this study is cited so often is, of course, that we could also show that the osseointegration in the Geistlich Bio-Oss® augmented area was just as good as in the native bone. This much more important finding was, at the time, just a side observation. ...
Specialized manufacturer and supplier of synthetic nano-hydroxyapatite and tricalcium phosphate materials marketed as nanoXIM, used to manufacture medical devices, oral care and food products.
No, in fact, when this technology is perfected the human body should be able to accept the artificial bones more readily than traditional bone substitutes. The living bone tissue grows into the wooden bone quicker because of their similarity in structure (more flexible and spongy). The artificial bone is not raw wood: it is treated first to isolate the carbon, so that it is basically charcoal. and then covered with calcium and the result is chemically transformed into carbonated hydroxyapatite. This technology shows great promise in reducing healing time and later fractures in surrounding bones.. ...
Providing next-generation solutions for orthopaedic repair, Kayal Orthopaedic surgeons are experts in progressive orthobiologic materials, like QuickSet™.. QuickSet is injectable bone cement thats composed of macroporous calcium phosphate. Used to fill bone voids and stabilize bone fragments during joint repair, this biologic substance supports new bone formation and encourages osseointegration (e.g., bone healing between natural bone and a bone implant). During healing, QuickSet is resorbed by the body and replaced with natural bone, which strengthens and restores the area.. Before recommending the use of QuickSet during your traditional or non-invasive orthopedic procedure, your NJ orthopaedic surgeon will carefully review your medical history, symptoms and treatment objectives. While not every patient is a candidate for QuickSet, many experience successful outcomes when this orthobiologic treatment option is used.. ...
Dr. Wang: Patients should not be too concerned if their surgeon plans to use autograft or allograft in their spine surgery. Autograft bone is considered the "gold standard" and is the most commonly used graft for spinal fusion. As we study the results of biologic materials and other graft replacements, the use of autograft will most likely diminish, being replaced by other bone graft products that are used as substitutes.. Allograft bone, especially in the cervical spine, works well and the risk of problems specific to the graft material is quite low. There are a number of allograft-derived bone graft extenders that are often used for bone graft replacement. These are commonly used in all areas of the spine. I would caution, although there are a large number of bone graft materials available for use, and they appear to be safe-there is limited evidence, studies, and data demonstrating they are effective.. I am always pushing surgeons to ask for more definitive data on the effectiveness of bone ...
The search for bone substitutes is a contemporary and relevant subject 9. The large number of studies that present new biomaterials or the further development of known biomaterials confirms this statement. Prior to February 2015, 3,266 studies were published describing porous and absorbable bone substitutes filling bone defects in experimental animals.. A large number of materials have been developed and tested, separately or combined, to increase the capacity of new bone formation. This continuous and effervescent development hinders the classification of these materials 9. In this review, we aimed to classify these materials according to the basic material used in the production of the bone substitute; however, there are overlaps between groups and many materials that are classified into the same group are not always similar. Most of the substitutes contained HA or other types of CPs or a combination of them as the basic material. The accumulated experience on modulating the resorption rate ...
The company grows its corals from selected species using patented technology to provide bioactivity and eliminate biological contamination. Different species are used for different applications. The corals are bred in a farm in the Arava desert near the Dead Sea, so they arent susceptible to marine pollution, contamination and or endangerment from human or marine activity. They also grow 10 times faster than in nature. They also avoid some of the difficulties with some organic grafts from animals or humans, the risk of rejection and transmission of disease ...
The new Accell Evo3 contains more of the patented Accell Bone Matrix than Integras previous generation Accell products. The optimised platform of Accell Evo3 enables the bone healing process to take advantage of the naturally available bone proteins found in DBM and ABM. Accell Evo3 is marketed in combination with a new custom designed open bore syringe.. Accell Evo3 may be used as a bone graft extender in the spine, extremities and pelvis or as bone void filler for the extremities and pelvis, and may replace the need to harvest bone graft material from the iliac crest, thus sparing the patient additional surgery and post-operative pain.. ...
This animal experiment compared the regenerative processes within defined bony defects of the porcine skull after delivery of routinely utilized bone graft materials: anorganic bone matrix (ABM) and an identical ABM carrying the cell binding peptide P-15. Particulated autogenous bone was used as a c …
The current designs of new biomaterials for bone substitutes or scaffolds focus on achieving biocompatibility and sufficient mechanical properties. In this thesis, we investigated the biocompatibility of synthetic polymers called aromatic thermosetting copolyesters (ATSP) as potential biomaterials for bone replacements (implants). These materials are easy to manufacture and have good mechanical properties such as high tensile strength, and high wear resistance. They can be made into bulk, film, foams, and composites. In this thesis, we included all these forms and created a composite by infusing ATSP with 10wt% of hydroxyapatite (minerals of similar compositions as those found in bone). Homogenous distribution of the HA filler improves the physical properties of composite ATSP. In addition to this, having robust adhesive features with metals, high energy absorption limit, and promising tribological properties makes ATSP a strong candidate for different orthopedic implant applications. This ...
Hydroxyapatite specially designed for medical applications. High osteoconductive and osteostimulative properties, biocompatible and non-toxic material, fully synthetic and safe raw material. Promotes bone regeneration and vascularization.
Provides a multifaceted approach to bone maintenance and strength, supports bone collagen formation, bone mineral density, and bone calcium binding sites.
An osteoconductive and osteoinductive biphasic ceramic replacement for bone loss could be an alternative to grafts. The safety and efficacy of this material has been shown in preclinical and clinical trials, demonstrating its suitability. An osteoconductive and osteoinductive biphasic ceramic replacement for bone loss
myotcstore.com - Buy over the counter medicines, vitamins, feminine needs, household and baby care items online at discount prices. Earn Reward Points on every purchase.
You are currently visiting Medline.com in Internet Explorer 8 which is not supported. Please upgrade your browser or switch to a supported browser. For a list of supported browsers visit: https://www.medline.com/help/tech-support/. ...
Geistlich Bio-Gide® Compressed should be used in combination with a void-filling bone graft material such as autologous bone or Geistlich Bio-Oss® or Geistlich Bio-Oss® Collagen. Application of Geistlich Bio-Gide® Compressed membrane is easy:. ...
The use of bone graft materials synthetic, autogenous, allogenous), GTR(barrier membranes), growth factors, PRF, enamel matrix proteins. Periodontal disease leads to bone loss and the patterns of bone destruction are broadly divided into horizontal and vertical or angular. Horizontal bone loss can be seen as loss of bone in a straight line on the radiograph. Vertical bone loss can be seen as saucer-shaped or v- shaped defects and can be filled with bone graft powders. A successful regenerative therapy stops the progress of the disease, helps to fill up the bone defects over 3-6 months and restores the support of the tooth.. 4. Orthodontic interrelationship. 5. Endo-perio management. There exists a communication between the opening of the tooth root(apical foramen) and the periodontium (gingival crevice). When infection from the tooth communicates with the gums or vice-versa, it is called an endo-perio lesion. In either cases, a root canal therapy is needed prior to gum surgery. Both the ...
Principal Investigator:Nagai Hirokazu, Project Period (FY):2015-04-01 - 2018-03-31, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:Surgical dentistry
Dental bone graft material, Bond Apatite by Augma Biomaterials is a revolutionery and a novel dental bone graft cement, Click to learn more about it!
Apr 2017 - 4.1 Mil Pg Views, March 2013 - Posted my paper introducing CLOUD COSMOLOGY & NEUTRAL NEUTRINO rigorously described as the SPACE TIME PENDULUM, September 2010 I am pleased to report that my essay titled A NEW METRIC WITH APPLICATIONS TO PHYSICS AND SOLVING CERTAIN HIGHER ORDERED DIFFERENTIAL EQUATIONS has been published in Physics Essays(AIP) and appeared in their June 2010 quarterly. 40 years ago I took an honors degree in applied mathematics from the University of Waterloo. My interest was Relativity and my last year there saw me complete a 900 level course under Hanno Rund on his work in relativity,as well as differential geometry(pure math) and of course analysis. I continued researching new ideas and knowledge since that time and I have prepared a book for publication titled Paradigms Shift&. I maintain my blog as a day book and research tool to retain data and record impressions and interpretations on material read. Do join my blog and receive Four items of interest daily Monday ...
TechCrunch is a leading technology media property, dedicated to obsessively profiling startups, reviewing new Internet products, and breaking tech news.
Placement apparatus and methods of use for impanation of spacers within an inter-vertebral disc space. In one embodiment, the load-bearing superstructure of the implant is subdivided and the bone forming material is positioned within an internal space of the placement instrument but external to the load bearing elements themselves. At least a portion of the bone graft material is freely contained within the disc space. A method of using the device is also described. In one embodiment, the placement device is used to place the implantable spacers at opposing ends of the disc space using a directly lateral surgical approach.
August 18, 2008 - ETEX Corp. launched EquivaBone, a bone graft substitute that remodels and is replaced with new bone during the healing process.. EquivaBone is a proprietary combination of osteoinductive Demineralized Bone Matrix (DBM) and ETEXs osteoconductive nanocrystalline calcium phosphate. ETEX now offers reportedly the first combination product that is both moldable and injectable and sets hard once implanted. In addition, osteoinductivity of the DBM is certified after sterilization, by lot, for the entirety of shelf life.. Both trauma and spine fusion data were included in the 510k submission which received FDA clearance on April 28, 2008. EquivaBone is intended for use in filling bone voids or defects of the skeletal system (including extremities, pelvis, and spine) that are not intrinsic to the stability of the bone structure.. For more information: www.etexcorp.com. ...
Geistlich Bio-Oss® Collagen contains the No 1 bone substitute Geistlich Bio-Oss® and additionally 10% of collagen. The pliable material is particularly easy to apply.
Abstract: Bony defects caused by periodontitis are often treated by regenerative therapy using autografts and/or allografts. Alloplasts such as hydroxyapatite or ceramics and bioactive glasses are used as osteoconductive materials that serve as scaffold for new bony ingrowth. The purpose of this study was to ascertain the possible regenerative capability of glass reinforced hydroxyapatite (Bonelike¬)¬¬¬ an osteoconductive synthetic graft in the treatment of human periodontal intrabony angular defects. The material was placed in 2 defects in 2 individual patients and clinical parameters such as probing depth (PD) and clinical attachment level (CAL) have been included. Bone fill was determined using an intra oral periapical radiograph (IOPA) and Autocad Software. After 3 months implantation period, there was an improvement in CAL and reduction in PD along with bone fill was observed ...
Delivery assembly for a liquid solution and granulated flakes of bone material. The device is capable of delivering multi component compound such as trinaric system, a liquid solution, living tissue cells and granulated flakes of bone material, or multi compound, to form a bone reconstruction compound and delivering the same. The delivered body of fluid is subjected to static head and dynamic head unclogging settled components and hold them as a body of fluid. The device includes a reservoir, a delivery tube, a moving member, designed to move and provide force or motion vector to the body of fluid in said tube, said reservoir is connected to said delivery tube with a passage allowing body of fluid to pass either by gravity, dynamic head provided by mixing device, or by static head.
MEMPHIS, Tenn. Sept. 28, 2006 Medtronic, Inc. (NYSE: MDT) today introduced two new synthetic bone graft products developed to provide surgeons with a comprehensive MASTERGRAFT ceramic option. MAS...
A bone replacement filler comprising a biomedical ceramic particulate, wherein the filler is able to flow without the application of an external shear stress or compressive force or under a relatively
Anatomy of the Filaga cruciate ligament. In the quest to understand mechanical impli- cations of structural hierarchies found in biological materials, multiscale mechanics may hold the key to understand вbuilding plansв inherent to entire material classes, here bone and bone replacement materials. Most, 1978 29.
Almost all your bodys calcium is stored in bone, but the tiny amount that circulates in your bloodstream is disproportionately vital to normal physiology.. About half of this circulating calcium (50%) is "ionized", which means it carries electrical charges.. Ionized calcium (Ca2+) is the only physiologically active form that can be recognized by our body and absorbed in our bones by stimulating hormones, which trigger the bone formation process .. Ionized calcium in the blood is so vital that the body cannot permit it to fluctuate. Therefore, even a slight increase in the concentration of ionized calcium in the blood triggers the bone building process to take excess calcium into bones.. Utilizing this process is by far the most effective and safe way to build bone density, since it follows the bodys natural bone building mechanism. ...
Dr. Oz discusses important bone health tips and how to maintain your bodys natural bone building process. Watch the video for tips and exercises.
Unlike other more invasive procedures MAKOplasty® can often be performed through a four to six inch incision over your knee with small incisions in both your femur (thigh bone) and tibia (shin). Additionally the preservation of your own natural bone and tissue along with more ideal patient specific implant positioning may also result in a more natural feeling knee. And since healthy bone is preserved, patients who undergo MAKOplasty® partial knee procedures may still be a candidate for a total knee replacement procedure later in life if necessary.. ...
Shop our carefully selected collection of dog treats and bones. Pig ears, natural bones, training treats and dental chews for dogs and puppies.
Shop our carefully selected collection of dog treats and bones. Pig ears, natural bones, training treats and dental chews for dogs and puppies.
The dramatic markings and variations inherent in natural bone give these eye-catching accents their unrivaled character. To create them, skilled artisans choose the most beautiful segments of salvaged buffalo bone, using heat and hand carving to c…
Skulls Unlimited International, Inc. is committed to providing legally and ethically obtained natural bone osteological specimens as well as the finest replica specimens to the educational, medical and research communities. Learn More ...
Illuminate, lift, and contour Enhance the elegance of your natural bone structure with this subtle illuminator and contouring liquid.
A spinal specialist may recommend that a patient undergo a corpectomy in some instances. A corpectomy is a surgical procedure on the spine. Corpectomy in its simplest sense means "remove the body." In this case there is a removal of vertebrae. A spinal surgeon will remove bones or discs to relieve the pressure on a patients nerves and spinal cord. During the procedure, the surgeon will remove portions of the bony sections which comprise the spinal column as well as discs that may be adjacent to the section being removed. Once the NJ spinal surgeon removes the discs and bones, there will be an empty space which will need to be reconstructed. The bones will be replaced through a bone graft or bone substitutes. In some cases there is missing tissue that is causing bone to rub against bone. The tissue must be reconstructed in order to prevent further damage. There are two basic reasons that a spine specialist might suggest a corpectomy for a patient: to remove pressure that is being put on the ...
In ottemperanza con quanto previsto dalla normativa vigente, dichiaro sotto la mia responsabilità di essere un professionista del settore odontoiatrico e di essere pertanto autorizzato a prendere visione del contenuto presente in questo sito internet ...
The maxgraft® bonebuilder is an innovative, customized allogenic bone block which is individually designed and adjusted to the desired 3-dimensional bone contour. Based on planning data and clinician-approved, the bonebuilder is produced by a milling machine and is provided in a sterile condition ready for implantation. The ideal bone substitute for rebuilding 3-dimensional defects and reconstructing the ridge, allowing a patient-friendly treatment ...
CeraPedics Inc., a Lakewood, Colo.-based developer of products for the orthopedic bone substitutes market, has raised $15 million in second-round funding,
Owing to its reliability and treatment predictability, bovine bone grafting material is the material of choice for the majority of dentists. cerabone® is a highly reliable, dimensionally stable and safe bone graft. It is derived from the mineral phase of bovine bone, which shows strong resemblance to the human bone with regard to chemical composition, porosity, and surface structure.
A 6-month Post-operative View of the same area showing resolution of the bony defect with osseous integration of the synthetic grafting material providing re-establishment of a solid lower boarder to the mandible with a couple of small calcific nodules in.. ...
Dental Product Shopper delivers practical, unbiased product information. Our peer to peer product reviews help you select the best products for your practice.
TY - JOUR. T1 - Effect of platelet-rich plasma on the healing of intrabony defects treated with beta tricalcium phosphate and expanded polytetrafluoroethylene membranes. AU - Döri, Ferenc. AU - Huszár, Tamás. AU - Nikolidakis, Dimitris. AU - Tihanyi, Dora. AU - Horváth, Attila. AU - Arweiler, Nicole B.. AU - Gera, I.. AU - Sculean, Anton. PY - 2008/4. Y1 - 2008/4. N2 - Background: Regenerative periodontal therapy using platelet-rich plasma (PRP) and different types of bone substitutes with or without guided tissue regeneration (GTR) has been proposed as a modality to enhance the outcome of regenerative surgery. However, there are limited data from controlled clinical studies evaluating the effect of PRP on the healing of deep intrabony defects treated with a combination of bone substitutes and GTR. The aim of this study was to clinically evaluate the effect of PRP on the healing of deep intrabony defects treated with beta tricalcium phosphate (β-TCP) and GTR by means of a non-bioresorbable ...
phdthesis{f7ddb7f0-7bc5-427f-bc3b-742fdbc376e4, abstract = {Two formulations of biphasic injectable bone substitutes have been developed for the treatment of bone defects and stabilisation of fragility fractures.,br/,,br, ,br/,,br, The first formulation consists of a calcium sulphate matrix with embedded hydroxyapatite (HA) particles to provide osteoconductivity. The mechanical properties of this formulation were investigated by focussing on the factors affecting the compressive strength of the bone substitute. It was found that the relation between liquid and powder in the formulation was the key factor. By adding less liquid the strength increased. However, a lower amount of liquid makes the paste difficult to inject. Other factors that affected the strength were the amount of HA particles, their size and morphology. Increased strength was obtained for a lower content of HA particles with smaller size and smaller specific surface area. It was possible to obtain a strength comparable to ...
In principle, bone has a good self-healing capacity. However, for defects larger than a certain size ("critical size defect") spontaneous healing of bone injury is not possible. Such defects can occur in many diseases such as osteoarthritis, bone cysts and tumors, or as a result of surgical procedures, for instance osteolyses associated with loosened endoprostheses or osteotomies. The gold standard for the treatment of bone defects is an autologous bone transplantation; however, disadvantages of the method include follow-up operations that are necessary in addition to the bone harvesting from the iliac crest, which are connected with significant comorbidity.1 Availability of natural bone is restricted and often not sufficient to heal large bone defects, while maintenance of an extensive bone bank is expensive and complicated by long-term tissue preservation issues. To overcome these difficulties, a number of synthetic and partial synthetic bone substitute materials have been developed. In ...
China Construction Application and Powder Shape Calcium Sulphate Dihydrate, Find details about China Calcium Sulphate, Calcium Sulfate from Construction Application and Powder Shape Calcium Sulphate Dihydrate - Zibo Qingxin Chemicals Co., Ltd.
Anti-static calcium sulphate access floor consists of high-density (1500Kg/m3 ) calcium sulphate core. Galvanized steel sheet is bonded to the bottom of the calcium sulphate core. HPL, PVC or ceramic is sticked to the top of the calcium sulphate...
More than a decade has passed since the first injectable bone substitutes were introduced for use in orthopaedic trauma, and over recent years the number of commercial products has increased dramatically. Despite the fact that these bone substitutes have been on the market for many years, knowledge amongst potential users on how and when they might be useful is still fairly limited. Most injectable bone substitutes belong to one of two major groups: by far the largest group contains products based on various calcium phosphate (CP) mixtures, whilst the smaller group consists of calcium sulphate (CS) compounds. Following mixing, the CP or CS paste can be injected into - for instance - a fracture space for augmentation as an alternative to bone graft, or around a screw for augmentation if the bone is weak. Within minutes an in situ process makes the substitute hard; the mechanical strength in compression resembles that of cancellous bone, whereas the strength in bending and shear is lower. Over ...
Europe Bone Replacement Market by Manufacturers, Countries, Type and Application, Forecast to 2022 is a market research report available at US $4480 for a Single User PDF License from RnR Market Research Reports Library.
There is an increasing need for synthetic bone substitute materials that decrease the need for allografts and autografts. In this study, composites of β-TCP and a biodegradable poly(L-lactide-co-ε-caprolactone) were manufactured using extrusion to form biodegradable composites with high β-TCP contents for osteoconductivity. The hydrolytic degradation of the composites containing 0, 10, 20, 35 and 50% of β-TCP was studied in vitro for 52 weeks. During the study, it was observed that β-TCP did not have an effect on the degradation rate of the polymer matrix. However, the crystallinity of the materials increased throughout the test series and changes in Tgs were also observed as the comonomer ratio of the polymer matrix changed as the degradation proceeded. The results show that the materials have desirable degradation properties and, thus, possess great potential as bioabsorbable and osteoconductive bone filling materials ...
The report Global Calcium Sulphate Industry 2016 Market Research Report provides major statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market. It provides a basic overview of the industry including definitions, classifications, applications and industry chain structure. The Calcium Sulphate market analysis is provided for the international market including development history, competitive landscape analysis, and major regions development status.. Then, the report focuses on global major leading industry players with information such as company profiles, product picture and specification, capacity, production, price, cost, revenue and contact information. Upstream raw materials, equipment and downstream consumers analysis is also carried out. Whats more, the Calcium Sulphate industry development trends and marketing channels are analyzed.. Request a Sample copy @ ...
Manufacturer of Calcium Sulphate Anhydrous, Suppliers of Calcium Sulphate Anhydrous, Dealers of Calcium Sulphate Anhydrous in UAE
Manufacturer of Calcium Sulphate Anhydrous, Suppliers of Calcium Sulphate Anhydrous, Dealers of Calcium Sulphate Anhydrous in Ethiopia
in European Journal of Oral Implantology (2015), 8(3), 233-244. PURPOSE: To evaluate the effectiveness of a bone substitute covered with a resorbable membrane versus open flap debridement for the treatment of periodontal infrabony defects. MATERIALS AND METHODS ... [more ▼]. PURPOSE: To evaluate the effectiveness of a bone substitute covered with a resorbable membrane versus open flap debridement for the treatment of periodontal infrabony defects. MATERIALS AND METHODS: Ninety-seven patients with one infrabony defect, which was 3 mm or deeper and at least 2 mm wide were randomly allocated either to grafting with a bone substitute covered with a resorbable barrier (BG group) or open flap debridement (OFD group) according to a parallel group design in five European centres. Blinded outcome measures assessed tooth loss, complications, patients satisfaction with treatment and aesthetics, changes in probing attachment levels (PAL), probing pocket depths (PPD), gingival recessions (REC), ...
Several studies demonstrated that the use of graft material has better clinical results for the treatment of intrabony defects. The purpose of this study is to compare the clinical and radiographic efficacy of alloplast (Biphasic calcium phosphate) and demineralized freeze-dried bone allograft (DFDBA) in treatment of periodontal intraosseous defects. A split mouth study was conducted in 20 subjects diagnosed with chronic periodontitis presenting atleast two intrabony defects in either arch. One quadrant (Site A) received alloplast (Biphasic calcium phosphate) and the contralateral defect (Site B) received DFDBA. The results of study showed that clinically Site B (DFDBA) showed greater reduction in pocket depth and gain in clinical attachment level than site A (Biphasic calcium phosphate), however it was not statistically significant. Site A (Biphasic calcium phosphate) showed slightly more gingival marginal recession than Site B (DFDBA). Radiographically Site B (DFDBA) showed greater bone fill ...
PURPOSE: The aim of this study was to compare ChronOS (β-tricalcium phosphate), Bio-Oss, and their addition to an autogenous bone graft in a 1:1 ratio in human maxillary sinus bone augmentation. MATERIALS AND METHODS: Thirty maxillary sinuses were divided in 5 groups: group 1 included 6 maxillary sinuses grafted with autogenous bone graft alone; group 2 included 6 maxillary sinuses grafted with ChronOS; group 3 included 6 maxillary sinuses grafted with ChronOS and autogenous bone graft in a 1:1 ratio; group 4 included 6 maxillary sinuses grafted with Bio-Oss; and group 5 included 6 maxillary sinuses grafted with Bio-Oss and autogenous bone graft in a 1:1 ratio ...
Bone graft substitutes are now commonly used in orthopaedic surgery as an alternative to autogenous bone graft. This short review will focus on applications of bone graft substitutes in sports medicine, trauma and spine surgery.. Sports medicine. There is a relative paucity of literature supporting the use of bone graft substitutes in sports medicine compared with trauma or spinal surgery. One of the most common bone grafting indications in sports medicine is opening wedge tibial osteotomy. When compared alongside autogenous iliac crest bone graft (AICBG), union of tibial osteotomy took longer and pain persisted longer when ceramic wedges were used. At six months post-operatively, there was no difference between the two groups in terms of union and outcome.1 Recently, the use of bone grafting in osteotomy has been questioned in a study that showed no difference in complications, union time and rate in grafted and non-grafted osteotomies.2 It is currently unclear whether there is a need to graft ...
TY - JOUR. T1 - A 6-month histological analysis on maxillary sinus augmentation with and without use of collagen membranes over the osteotomy window. T2 - Randomized clinical trial. AU - Barone, A.. AU - Ricci, M.. AU - Grassi, R. F.. AU - Nannmark, U.. AU - Quaranta, A.. AU - Covani, U.. PY - 2013/1. Y1 - 2013/1. N2 - Introduction: Over the years, several modifications have been made to the sinus augmentation technique and to the materials used. However, there is still controversy about the need for using a barrier concurrently with a graft in sinus augmentation procedures. On this basis, the aim of this randomized clinical study was to investigate the effect of resorbable collagen membrane over the osteotomy window on maxillary sinus augmentation healing. Materials and methods: Patients who required maxillary sinus augmentation were evaluated and selected to enter the study. After maxillary sinus grafting, each patient was randomly assigned to control (membrane over the osteotomy window) or ...
1. Chambrone L, Preshaw PM, Ferreira JD, et al. Effects of tobacco smoking on the survival rate of dental implants placed in areas of maxillary sinus floor augmentation: A systematic review. Clin Oral Implants Res. 2014;2w5(4):408-416.. 2. Wallace SS, Froum SJ. Effect of maxillary sinus augmentation on the survival of endosseous dentawl implants. A systematic review. Ann Periodontol. 2013;8(1):328-343.. 3. Ghasemi S, Fotouhi A, Moslemi N, et al. Intra- and postoperative complications of lateral maxillary sinus augmentation in smokers vs nonsmokers: A systematic review and meta-analysis. Int J Oral Maxillofac Implants. 2017;32(4):759-767.. 4. Kozuma A, Sasaki M, Seki K, et al. Preoperative chronic sinusitis as significant cause of postoperative infection and implant loss after sinus augmentation from a lateral approach. Oral Maxillofac Surg. 2017;21(2):193-200.. 5. Marx RE. Platelet-rich plasma: Evidence to support its use. J Oral Maxillofac Surg. 2004;62(4):489-496.. 6. Marx RE, Carlson ER, ...
DOI: 10.11607/prd.00.0110 The purpose of this study was to evaluate: (1) the surgical protocol, effectiveness, and reliability for vertical ridge augmentation using a new titanium-reinforced membrane and osseointegrated implants; and (2) the histologic characteristics of the interface between a pure titanium implant and newly regenerated human bone. Five patients received 15 conical Br nemark-type implants in six different surgical sites requiring vertical augmentation. The implants protruded 4 to 7 mm from the bone crest. Pure titanium miniscrews (1.3 x 10 mm) were positioned distally to the implants, protruding 3 to 4 mm from the bone level. The implants and the miniscrews were covered with a titanium-reinforced membrane, and the flaps were sutured. Membranes were removed at the stage 2 surgery after 9 months of healing. Measurements of biopsy specimens showed a gain in bone height from 3 to 4 mm. Histologic examination showed that all retrieved miniscrews were in direct contact with bone. ...
DOI: 10.11607/prd.00.0342 The aim of the present study was to evaluate clinically and histologically the treatment of intrabony periodontal defects with a bioresorbable membrane barrier. Fifty-two intrabony periodontal defects were treated according to the principles of guided tissue regeneration (GTR) with a bioresorbable membrane. Results were evaluated by assessing probing pocket depth, recession of the gingival margin, and clinical attachment level at baseline and at 1 and 2 years after therapy. Bone level changes were evaluated radiographically. The postoperative phase was uneventful in all cases. There was a mean probing pocket depth reduction from 8.4 to 3.6 mm, a mean increase of gingival margin recession from 1.5 to 3.0 mm, and a mean clinical attachment level change from 9.9 to 6.5 mm. Mean attachment gain was 3.4 mm. Two teeth scheduled for extraction were also treated with the same bioresorbable membrane. The histologic analysis 6 months after treatment revealed the formation of new ...
TY - JOUR. T1 - Simultaneous electrospin-electrosprayed biocomposite nanofibrous scaffolds for bone tissue regeneration. AU - Francis, Lijo. AU - Venugopal, J.. AU - Prabhakaran, Molamma P.. AU - Thavasi, V.. AU - Marsano, E.. AU - Ramakrishna, S.. PY - 2010/10. Y1 - 2010/10. N2 - Currently, the application of nanotechnology in bone tissue regeneration is a challenge for the fabrication of novel bioartificial bone grafts. These nanostructures are capable of mimicking natural extracellular matrix with effective mineralization for successful regeneration of damaged tissues. The simultaneous electrospraying of nanohydroxyapatite (HA) on electrospun polymeric nanofibrous scaffolds might be more promising for bone tissue regeneration. In the current study, nanofibrous scaffolds of gelatin (Gel), Gel/HA (4:1 blend), Gel/HA (2:1 blend) and Gel/HA (electrospin-electrospray) were fabricated for this purpose. The morphology, chemical and mechanical stability of nanofibres were evaluated by means of field ...

Injectable calcium sulphate and calcium phosphate bone substitutesInjectable calcium sulphate and calcium phosphate bone substitutes

This bone substitute showed a favourable tissue response in both rat muscles and rabbit bone. New ingrowing bone was in direct ... This bone substitute showed a favourable tissue response in both rat muscles and rabbit bone. New ingrowing bone was in direct ... Two formulations of biphasic injectable bone substitutes have been developed for the treatment of bone defects and ... Two formulations of biphasic injectable bone substitutes have been developed for the treatment of bone defects and ...
more infohttps://lup.lub.lu.se/search/publication/465520

Examining Bone Substitute MaterialsExamining Bone Substitute Materials

Does anyone have information regarding defatting and dehydration of bone containing calcium sulfate type bone substitute ... Examining Bone Substitute Materials. ,, Previous Message , Next Message ,, From:. Catherine Ambrose ,[email protected] ... but I was thinking that others may have already had some experience with these bone substitute materials? ,, Previous Message ...
more infohttp://www.histosearch.com/histonet/Apr99A/ExaminingBoneSubstituteMa.html

Calcium Sulfate Used as Bone Graft Substitute in Acetabular Fracture FixationCalcium Sulfate Used as Bone Graft Substitute in Acetabular Fracture Fixation

... of the pellets had been replaced by bone. However, in five patients, less than 50% of the pellets had been replaced by bone, ... Computed tomography analysis showed that in 22 patients, the pellets essentially had been (> 90%) replaced by bone and in four ... Patients with the best results had complete containment of the pellets within bone. Therefore, it seems that implanted calcium ... Evaluation of plain radiographs showed that the calcium sulfate pellets became undifferentiated from the surrounding bone at an ...
more infohttps://insights.ovid.com/article/00003086-200305000-00037

Patent US5614206 - Controlled dissolution pellet containing calcium sulfate - Google PatentsPatent US5614206 - Controlled dissolution pellet containing calcium sulfate - Google Patents

Bone Support Ab. Device for providing spongy bone with bone substitute and/or bone reinforcing material, bone substitute and/or ... Bone Support Ab. Device for providing spongy bone with bone substitute and/or bone reinforcing material, bone substitute and/or ... Device for providing spongy bone with bone substitute and/or bone reinforcing material, bone substitute and/or bone reinforcing ... Bone Support Ab. Device for producing a hardenable mass. US8420127. 5 Mar 2004. 16 Apr 2013. Bone Support Ab. Bone substitute ...
more infohttp://www.google.co.uk/patents/US5614206

Calcium sulfate barrier for regeneration of human bone defects. 3 years randomized controlled study - Minerva Stomatologica...Calcium sulfate barrier for regeneration of human bone defects. 3 years randomized controlled study - Minerva Stomatologica...

Calcium phosphate ceramics have been widely applied as bone substitutes, coatings, cements, drug delivery systems and tissue ... This study has evaluates the bone tissue behavior of calcium sulfate barrier in bone repair in human bone, observing the GBR ... 10 patients using BondBone and a Collagen membrane and the remaining 10 patients with Bone substitute and a collagen membrane. ... The guided bone regeneration (GBR) principles are applied in the rebuilding of periodontal tissues, damaged by the periodontal ...
more infohttps://www.minervamedica.it/en/journals/minerva-stomatologica/article.php?cod=R18Y9999N00A0006

Patent US6527810 - Bone substitutes - Google PatentsPatent US6527810 - Bone substitutes - Google Patents

... porous article useful as a bone substitute material. The article comprises a continuous strong framework structure having ... The bone substitute materials of the invention can be formed into the appropriate configurations for use as a bone substitute ... Intimate, load carrying contact often is required between the natural bone and the bone substitute material to promote bone ... and bone cancers may call for treatment involving the use of structural bone substitute materials. A successful bone graft ...
more infohttp://www.google.ca/patents/US6527810

Bone Graft SubstitutesBone Graft Substitutes

... including demineralized bone matrix (DBM), synthetic bone graft extenders and bone morphogenetic proteins (BMP). ... A variety of bone graft substitutes are available or being investigated for use in spine fusion surgery, ... Demineralized Bone Matrix (DBM). Processing of allograft bone (cadaver bone graft) can be manipulated (demineralized) to ... There are a variety of bone graft substitutes that are available for use in spine fusion surgery or are being evaluated in ...
more infohttps://www.spine-health.com/treatment/spinal-fusion/bone-graft-substitutes

Substitutes for bone meal for plantsSubstitutes for bone meal for plants

... a mixture of finely-crushed bones that is a slow-release organic fertiliser. It does not pollute the environment like many ... Bone meal is a byproduct of animal rendering, ... Substitutes for bone meal for plants. By: J. Lang Wood. Updated ... It has a high phosphorus content and is used to increase the fertility of soils and as a substitute for bone meal. It is ... Poultry manure is an organic fertiliser that is naturally high in phosphorus and can be used as a substitute for bone meal. All ...
more infohttps://www.ehow.co.uk/list_7562253_substitutes-bone-meal-plants.html

Patent US7371410 - Bone graft substitute composition - Google PatentsPatent US7371410 - Bone graft substitute composition - Google Patents

A bone graft substitute composition can include calcium sulfate, demineralized bone matrix, cancellous bone, a plasticizing ... A bone graft substitute composition can include essentially of calcium sulfate, a mixing solution, and a plasticizing substance ... Bone graft substitute composition. US8968465. 16 Jan 2014. 3 Mar 2015. Wright Medical Technology, Inc.. Bone graft substitute ... A bone graft substitute composition can include calcium sulfate, demineralized bone matrix, cancellous bone, a plasticizing ...
more infohttp://www.google.ca/patents/US7371410

Bone SubstitutesBone Substitutes

Effect of recombinant human bone morphogenetic protein 2 associated with a variety of bone substitutes on vertical guided bone ... Radiographic Comparison of Bovine Bone Substitute Alone Versus Bovine Bone Substitute and Simvastatin for Human Maxillary Sinus ... The influence of bone substitute materials on the bone volume after maxillary sinus augmentation: a microcomputerized ... Alveolar ridge preservation with guided bone regeneration and a synthetic bone substitute or a bovine-derived xenograft: a ...
more infohttps://www.straumann.com/fi/en/dental-professionals/science/literature/bone-substitutes.html

Bone SubstitutesBone Substitutes

Effect of recombinant human bone morphogenetic protein 2 associated with a variety of bone substitutes on vertical guided bone ... Radiographic Comparison of Bovine Bone Substitute Alone Versus Bovine Bone Substitute and Simvastatin for Human Maxillary Sinus ... The influence of bone substitute materials on the bone volume after maxillary sinus augmentation: a microcomputerized ... Alveolar ridge preservation with guided bone regeneration and a synthetic bone substitute or a bovine-derived xenograft: a ...
more infohttps://www.straumann.com/dk/en/dental-professionals/science/literature/bone-substitutes.html

Testing bone substitutes in a small animal model of revision arthroplasty | SpringerLinkTesting bone substitutes in a small animal model of revision arthroplasty | SpringerLink

This study evaluated a modification of the rat-pin model to enable testing of bone substitute materials. The model was ... Hydroxyapatite Toluidine Blue Proximal Tibia Bone Substitute Tartrate Resistant Acid Phosphatase These keywords were added by ... This study evaluated a modification of the rat-pin model to enable testing of bone substitute materials. The model was ... S. Louisia, M. Stromboni, A. Meunier, L. Sedel and H. Petite, J. Bone Joint Surg. Br. Vol. 81B (1999) 719.Google Scholar ...
more infohttps://link.springer.com/article/10.1023%2FA%3A1016540110569

Global Synthetic Bone Graft Substitutes Sales Market Shares,Global Synthetic Bone Graft Substitutes Sales Market Shares,

... Emerging Technologies, Leisure Application & Gross Revenues 2016 ... 2.2 Global Synthetic Bone Graft Substitutes (Volume and Value) by Type. 2.2.1 Global Synthetic Bone Graft Substitutes Sales and ... 2.3 Global Synthetic Bone Graft Substitutes (Volume and Value) by Regions. 2.3.1 Global Synthetic Bone Graft Substitutes Sales ... 1 Synthetic Bone Graft Substitutes Overview. 1.1 Product Overview and Scope of Synthetic Bone Graft Substitutes. 1.2 ...
more infohttps://www.openpr.com/news/412344/global-synthetic-bone-graft-substitutes-sales-market-shares-emerging-technologies-leisure-application-gross-revenues-2016.html

Global Bone Graft Substitutes Market 2017 by top Manufacturers -... - FMR NewsGlobal Bone Graft Substitutes Market 2017 by top Manufacturers -... - FMR News

Report studies Bone Graft Substitutes in Global market that focuses on the top Manufacturers, Market Segment by Countries, ... global bone graft substitutes marketglobal bone graft substitutes market shareglobal bone graft substitutes market trendglobal ... 1 Bone Graft Substitutes Market Overview. 1.1 Product Overview and Scope of Bone Graft Substitutes. 1.2 Bone Graft Substitutes ... Global Bone Graft Substitutes Market 2017 by top Manufacturers - Sunstar, Geistlich, Zimmer Biomet. Press Release • Aug 23, ...
more infohttp://www.mynewsdesk.com/in/pressreleases/global-bone-graft-substitutes-market-2017-by-top-manufacturers-sunstar-geistlich-zimmer-biomet-2118536

Bone and Tendon Graft Substitutes and Adjuncts (037) - Dental CPBs | AetnaBone and Tendon Graft Substitutes and Adjuncts (037) - Dental CPBs | Aetna

Read about Aetnas policy on bone and tendon graft substitutes and adjuncts in Dental CPB 037. ... Bone and Tendon Graft Substitutes and Adjuncts. March 29, 2017: This CPB is revised to state that the INFUSE Bone Graft is ... INFUSE Bone Graft is to be used with a cage; 2) INFUSE Bone Graft and device is to be implanted via an anterior approach; 3) ...
more infohttps://www.aetna.com/health-care-professionals/clinical-policy-bulletins/dental-clinical-policy-bulletins/DCPB037.html

9780803133563: Bone Graft Substitutes - AbeBooks - Cato T. Laurencin: 08031335619780803133563: Bone Graft Substitutes - AbeBooks - Cato T. Laurencin: 0803133561

Bone Graft Substitutes (9780803133563) by Cato T. Laurencin and a great selection of similar New, Used and Collectible Books ... Factor Based Systems for Use as Bone Graft Substitutes: A Review of the State of the Art: · Bone Morphogenetic Protein (BMP) ... Cell Based Approach for Bone Graft Substitutes · Clinical Issues in the Development of Cellular Systems for Use as Bone Graft ... Section 1 presents a summary of the clinical use of bone allografts and allograft-based bone graft substitutes. Chapters ...
more infohttps://www.abebooks.com/9780803133563/Bone-Graft-Substitutes-Laurencin-Cato-0803133561/plp

Small-sized granules of biphasic bone substitutes support fast implant bed vascularization.  - PubMed - NCBISmall-sized granules of biphasic bone substitutes support fast implant bed vascularization. - PubMed - NCBI

shows SEM pictures of the analyzed bone substitute granules. A1-3 show the properties of BoneCeramic (BC) with granule sizes ... Small-sized granules of biphasic bone substitutes support fast implant bed vascularization.. Barbeck M1, Dard M, Kokkinopoulou ... shows TEM images of the mononuclear cells involved in the tissue reactions to the BoneCeramic 400-700 µm (BC) bone substitute ... shows the tissue reactions as well as the vascularization pattern of the 2 analyzed bone substitute granule types, BoneCeramic ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/26083163

Cranioplasty: Autogenous Bone Graft Versus Artificial Substitutes - Full Text View - ClinicalTrials.govCranioplasty: Autogenous Bone Graft Versus Artificial Substitutes - Full Text View - ClinicalTrials.gov

Cranioplasty: Autogenous Bone Graft Versus Artificial Substitutes. The safety and scientific validity of this study is the ... autologous bone group patient underwent to cranioplasty reconstruction with autologous bone graft ... with autologous bone graft , bone cement or titanium mesh and to compare the clinical outcome and safety among the 3 types of ... Autologous bone grafts remain the best option for adult and pediatric patients with viable donor sites and small-to-medium ...
more infohttps://clinicaltrials.gov/ct2/show/NCT03218150?term=Traumatic+Brain+Injury&

Patente US7972630 - Injectable bone mineral substitute material - Google PatentesPatente US7972630 - Injectable bone mineral substitute material - Google Patentes

An injectable bone mineral substitute material composition comprises an inorganic bone cement powder and a biologically ... Device for providing spongy bone with bone substitute and/or bone reinforcing material, bone substitute and/or bone reinforcing ... Bone Support Ab. Bone substitute composition. US8586101. 20 Dic 2002. 19 Nov 2013. Bone Support Ab. Bioresorbable bone mineral ... Bone substitute composition. US20070186819 *. 24 Abr 2007. 16 Ago 2007. Wright Medical Technology, Inc.. Bone Graft Substitute ...
more infohttp://www.google.es/patents/US7972630?dq=flatulence

Bone graft substitutes in anterior cervical discectomy and fusion | SpringerLinkBone graft substitutes in anterior cervical discectomy and fusion | SpringerLink

Pan H-C, Wang Y-C, Lee C-H, Yang D-Y (2007) Hollow bone cement filled with impacted cancellous bone as a substitute for bone ... Cell-based approaches for bone graft substitutes. In: Laurencin CT (ed) bone graft substitutes. ASTM International, West ... Shors EC (2003) The development of corraline porous ceramic bone. In: Laurencin CT (ed) Bone graft substitutes. ASTM ... Bone graft substitutes: basic information for successful clinical use with special focus on synthetic graft substitutes. In: ...
more infohttps://link.springer.com/article/10.1007/s00586-008-0878-4

Researchers produce bone substitutes from eggshells - Daijiworld.comResearchers produce bone substitutes from eggshells - Daijiworld.com

The research seeks to produce bone substitute materials such as I-tricalcium phosphate (I-TCP), a commonly-used bone substitute ... or bone grafting in which materials having calcium were combined with the latex of the banyan tree to form bone substitutes. ... Researchers produce bone substitutes from eggshells. * Wed, Aug 14 2019 01:30:47 PM ... In modern medicine, damaged and missing bones are replaced with bone from either patient or donor or using artificial materials ...
more infohttps://www.daijiworld.com/news/newsDisplay.aspx?newsID=614667

Using Combination of Synthetic Bone Substitutes During Extractions - Full Text View - ClinicalTrials.govUsing Combination of Synthetic Bone Substitutes During Extractions - Full Text View - ClinicalTrials.gov

Bone Resorption. Bone Diseases. Musculoskeletal Diseases. Periodontal Atrophy. Calcium, Dietary. Bone Density Conservation ... Using Combination of Synthetic Bone Substitutes During Extractions. The safety and scientific validity of this study is the ... Extraction of teeth and implant a bone substitute. Device: Calcium Phosphate, Calcium Sulphate 1cc of Calcium Phosphate and 1cc ... Using the combination of these two bone substitute is taken in order to diminish the alveolar ridge alternations after tooth ...
more infohttps://clinicaltrials.gov/ct2/show/NCT01503593?recr=Open&intr=dietary+calcium&rank=17

FDA: Providers should avoid using certain bone graft substitutes in children | AHA NewsFDA: Providers should avoid using certain bone graft substitutes in children | AHA News

The Food and Drug Administration today advised against routine use of bone graft substitutes containing recombinant proteins ... FDA: Providers should avoid using certain bone graft substitutes in children Jan 21, 2015 - 04:19 PM ... The Food and Drug Administration today advised against routine use of bone graft substitutes containing recombinant proteins ...
more infohttps://www.aha.org/news/headline/2015-01-21-fda-providers-should-avoid-using-certain-bone-graft-substitutes-children

Biotechnology startup receives FDA clearance for synthetic bone graft substituteBiotechnology startup receives FDA clearance for synthetic bone graft substitute

... has received Food and Drug Administration clearance for a carbohydrate-based polymer that can help injured bones heal and ... a synthetic bone graft substitute, supports and guides the growth of new bone -- such as when there is a loss of bone due to ... "The need for bone substitute products is expected to expand," said Jim Keefer, COO of Molecular Matrix. "The global bone graft ... Biotechnology startup receives FDA clearance for synthetic bone graft substitute. *Download PDF Copy ...
more infohttps://www.news-medical.net/news/20180127/Biotechnology-startupc2a0receives-FDA-clearance-for-synthetic-bone-graft-substitute.aspx

Global Dental Bone Graft and Substitutes Market - Trends and... - Coherent Market Insights Pvt LtdGlobal Dental Bone Graft and Substitutes Market - Trends and... - Coherent Market Insights Pvt Ltd

The global dental bone graft and substitutes market was valued at US$ 418.4 million in 2016 and is expected to witness a robust ... Dental Bone Graft and Substitutes Market Insights. Dental bone grafts are used as fillers or scaffolds that facilitate bone ... Development of novel bone graft substitutes is expected to boost growth of the dental bone graft and substitutes market ... dental bone graft and substitutes marketdental bone graft and substitutes market report ...
more infohttp://www.mynewsdesk.com/us/pressreleases/global-dental-bone-graft-and-substitutes-market-trends-and-forecast-to-2025-2365940
  • Apatitic bone substitutes have shown excellent biocompatibility but slow resorption in the human body. (lu.se)
  • The study group consisted of patients sustaining an acetabular fracture with intraarticular comminution or marginal impaction or both in whom calcium sulfate pellets were implanted in lieu of autologous bone graft. (ovid.com)
more