Bone neoplasms. Medical search

Tumors or cancer located in bone tissue or specific BONES.

A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.

The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.

Bone loss due to osteoclastic activity.

The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.

Cells contained in the bone marrow including fat cells (see ADIPOCYTES); STROMAL CELLS; MEGAKARYOCYTES; and the immediate precursors of most blood cells.

The growth and development of bones from fetus to adult. It includes two principal mechanisms of bone growth: growth in length of long bones at the epiphyseal cartilages and growth in thickness by depositing new bone (OSTEOGENESIS) with the actions of OSTEOBLASTS and OSTEOCLASTS.

Diseases of BONES.

Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.

Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Extracellular substance of bone tissue consisting of COLLAGEN fibers, ground substance, and inorganic crystalline minerals and salts.

Connective tissue cells of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere.

Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES.

The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.

Progenitor cells from which all blood cells derive.

The result of a positive or negative response (to drugs, for example) in one cell being passed onto other cells via the GAP JUNCTIONS or the intracellular milieu.

Neoplasms composed of bony tissue, whether normal or of a soft tissue which has become ossified. The concept does not refer to neoplasms located in bones.

Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.

Neoplasms developing from some structure of the connective and subcutaneous tissue. The concept does not refer to neoplasms located in connective or soft tissue.

Neoplasms composed of tissues of the OVARY or the TESTIS, not neoplasms located in the ovaries or testes. Gonadal tissues include GERM CELLS, cells from the sex cord, and gonadal stromal cells.

Neoplasms composed of fatty tissue or connective tissue made up of fat cells in a meshwork of areolar tissue. The concept does not refer to neoplasms located in adipose tissue.

Neoplasms composed of nerve tissue. This concept does not refer to neoplasms located in the nervous system or its component nerves.

The last bone in the VERTEBRAL COLUMN in tailless primates considered to be a vestigial tail-bone consisting of three to five fused VERTEBRAE.

Bones that constitute each half of the pelvic girdle in VERTEBRATES, formed by fusion of the ILIUM; ISCHIUM; and PUBIC BONE.

Five fused VERTEBRAE forming a triangle-shaped structure at the back of the PELVIS. It articulates superiorly with the LUMBAR VERTEBRAE, inferiorly with the COCCYX, and anteriorly with the ILIUM of the PELVIS. The sacrum strengthens and stabilizes the PELVIS.

Mammals of the family Phocoenidae comprising four genera found in the North Pacific Ocean and both sides of the North Atlantic Ocean and in various other seas. They differ from DOLPHINS in that porpoises have a blunt snout and a rather stocky body while dolphins have a beak-like snout and a slender, streamlined body. They usually travel in small groups. (From Walker's Mammals of the World, 5th ed, pp1003-4)

A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.

The comparative study of animal structure with regard to homologous organs or parts. (Stedman, 25th ed)

A type II keratin that is found associated with the KERATIN-10 in terminally differentiated epidermal cells such as those that form the stratum corneum. Mutations in the genes that encode keratin-1 have been associated with HYPERKERATOSIS, EPIDERMOLYTIC.

Centers for acquiring, characterizing, and storing organs or tissue for future use.

Using fine needles (finer than 22-gauge) to remove tissue or fluid specimens from the living body for examination in the pathology laboratory and for disease diagnosis.

A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.

A polymer prepared from polyvinyl acetates by replacement of the acetate groups with hydroxyl groups. It is used as a pharmaceutic aid and ophthalmic lubricant as well as in the manufacture of surface coatings artificial sponges, cosmetics, and other products.

A product formed from skin, white connective tissue, or bone COLLAGEN. It is used as a protein food adjuvant, plasma substitute, hemostatic, suspending agent in pharmaceutical preparations, and in the manufacturing of capsules and suppositories.

A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.

Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.

A subclass of iridoid compounds that include a glycoside moiety, usually found at the C-1 position.

A system of categories to which morbid entries are assigned according to established criteria. Included is the entire range of conditions in a manageable number of categories, grouped to facilitate mortality reporting. It is produced by the World Health Organization (From ICD-10, p1). The Clinical Modifications, produced by the UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES, are larger extensions used for morbidity and general epidemiological purposes, primarily in the U.S.

Bony structure of the mouth that holds the teeth. It consists of the MANDIBLE and the MAXILLA.

Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.

Process of substituting a symbol or code for a term such as a diagnosis or procedure. (from Slee's Health Care Terms, 3d ed.)

Tumors or cancer of the MANDIBLE.

Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.

Presentations of summary statements representing the majority agreement of physicians, scientists, and other professionals convening for the purpose of reaching a consensus--often with findings and recommendations--on a subject of interest. The Conference, consisting of participants representing the scientific and lay viewpoints, is a significant means of evaluating current medical thought and reflects the latest advances in research for the respective field being addressed.

Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.

Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.

A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round "blue cells", granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small ("oat") cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)

Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.

Relative efficacy of 32P and 89Sr in palliation in skeletal metastases. (1/5419)

32p and 89Sr have been shown to produce significant pain relief in patients with skeletal metastases from advanced cancer. Clinically significant pancytopenia has not been reported in doses up to 12 mCi (444 MBq) of either radionuclide. To date, no reports comparing the relative efficacy and toxicity of the two radionuclides in comparable patient populations have been available. Although a cure has not been reported, both treatments have achieved substantial pain relief. However, several studies have used semiquantitative measures such as "slight," "fair," "partial" and "dramatic" responses, which lend themselves to subjective bias. This report examines the responses to treatment with 32P or 89Sr by attempting a quantification of pain relief and quality of life using the patients as their own controls and compares toxicity in terms of hematological parameters. METHODS: Thirty-one patients with skeletal metastases were treated for pain relief with either 32P (16 patients) or 89Sr (15 patients). Inclusion criteria were pain from bone scan-positive sites above a subjective score of 5 of 10 despite analgesic therapy with narcotic or non-narcotic medication, limitation of movement related to the performance of routine daily activity and a predicted life expectancy of at least 4 mo. The patients had not had chemotherapy or radiotherapy during the previous 6 wk and had normal serum creatinine, white cell and platelet counts. 32P was given orally as a 12 mCi dose, and 89Sr was given intravenously as a 4 mCi (148 MBq) dose. The patients were monitored for 4 mo. RESULTS: Complete absence of pain was seen in 7 of 16 patients who were given 32P and in 7 of 15 patients who were given 89Sr. Pain scores fell by at least 50% of the pretreatment score in 14 of 16 patients who were given 32P and 14 of 15 patients who were given 89Sr. Mean duration of pain relief was 9.6 wk with 32P and 10 wk with 89Sr. Analgesic scores fell along with the drop in pain scores. A fall in total white cell, absolute granulocyte and platelet counts occurred in all patients. Subnormal values of white cells and platelets were seen in 5 and 7 patients, respectively, with 32P, and in 0 and 4 patients, respectively, after 89Sr therapy. The decrease in platelet count (but not absolute granulocyte count) was statistically significant when 32P patients were compared with 89Sr patients. However, in no instance did the fall in blood counts require treatment. Absolute granulocyte counts did not fall below 1000 in any patient. There was no significant difference between the two treatments in terms of either efficacy or toxicity. CONCLUSION: No justification has been found in this study for the recommendation of 89Sr over the considerably less expensive oral 32P for the palliation of skeletal pain from metastases of advanced cancer. (+info)

A fluorescent orthotopic bone metastasis model of human prostate cancer. (2/5419)

Here, we report a fluorescent spontaneous bone metastatic model of human prostate cancer developed by surgical orthotopic implantation of green fluorescent protein (GFP)-expressing prostate cancer tissue. Human prostate cancer PC-3 cells were transduced with the pLEIN expression retroviral vector containing the enhanced GFP and neomycin resistance genes. Stable GFP high-expression PC-3 clones were selected in vitro with G418, which were then combined and injected s.c. in nude mice. For metastasis studies, fragments of a single highly fluorescent s.c. growing tumor were implanted by surgical orthotopic implantation in the prostate of a series of nude mice. Subsequent micrometastases and metastases were visualized by GFP fluorescence throughout the skeleton, including the skull, rib, pelvis, femur, and tibia The central nervous system, including the brain and spinal cord, was also involved with tumor, as visualized by GFP fluorescence. Systemic organs, including the lung, plural membrane, liver, kidney, and adrenal gland, also had fluorescent metastases. The metastasis pattern in this model reflects the bone and other metastatic sites of human prostate cancer. Thus, this model should be very useful for the study and development of treatment for metastatic androgen-independent prostate cancer. (+info)

Ibandronate reduces osteolytic lesions but not tumor burden in a murine model of myeloma bone disease. (3/5419)

We determined the effects of the potent bisphosphonate ibandronate in a murine model of human myeloma bone disease. In this model, bone lesions typical of the human disease develop in mice following inoculation of myeloma cells via the tail vein. Treatment with ibandronate (4 micrograms per mouse per day) significantly reduced the occurrence of osteolytic bone lesions in myeloma-bearing mice. However, ibandronate did not prevent the mice from developing hindlimb paralysis and did not produce a detectable effect on survival. There was no significant effect of ibandronate on total myeloma cell burden, as assessed by morphometric measurements of myeloma cells in the bone marrow, liver, and spleen, or by measurement of serum IgG2b levels. These results support clinical findings that bisphosphonates may be useful for the treatment of myeloma-associated bone destruction, but suggest that other therapies are also required to reduce tumor growth. (+info)

Gastrin-releasing peptide receptors in the human prostate: relation to neoplastic transformation. (4/5419)

Bombesin-like peptides such as gastrin-releasing peptide (GRP) have been shown to play a role in cancer as autocrine growth factors that stimulate tumor growth through specific receptors. To search for potential clinical indications for GRP analogues, it is important to identify human tumor types expressing sufficient amounts of the respective receptors. In the present study, we have evaluated the expression of GRP receptors in human nonneoplastic and neoplastic prostate tissues using in vitro receptor autoradiography on tissue sections with 125I-Tyr4-bombesin as radio-ligand. GRP receptors were detected, often in high density, in 30 of 30 invasive prostatic carcinomas and also in 26 of 26 cases of prostatic intraepithelial proliferative lesions, corresponding mostly to prostatic intraepithelial neoplasias. Well-differentiated carcinomas had a higher receptor density than poorly differentiated ones. Bone metastases of androgen-independent prostate cancers were GRP receptor-positive in 4 of 7 cases. Conversely, GRP receptors were identified in only a few hyperplastic prostates and were localized in very low density in glandular tissue and, focally, in some stromal tissue. In all of the cases, the receptors corresponded to the GRP receptor subtype of bombesin receptors, having high affinity for GRP and bombesin and lower affinity for neuromedin B. These data demonstrate a massive GRP receptor overexpression in prostate tissues that are neoplastically transformed or, like prostatic intraepithelial neoplasias, are in the process of malignant transformation. GRP receptors may be markers for early molecular events in prostate carcinogenesis and useful in differentiating prostate hyperplasia from prostate neoplasia Such data may not only be of biological significance but may also provide a molecular basis for potential clinical applications such as GRP-receptor scintigraphy for early tumor diagnosis, radiotherapy with radiolabeled bombesin-like peptide analogues, and chemotherapy with cytotoxic bombesin analogues. (+info)

Prognostic significance of extent of disease in bone in patients with androgen-independent prostate cancer. (5/5419)

PURPOSE: To evaluate the prognostic significance of a bone scan index (BSI) based on the weighted proportion of tumor involvement in individual bones, in relation to other factors and to survival in patients with androgen-independent prostate cancer. PATIENTS AND METHODS: Baseline radionuclide bone scans were reviewed in 191 assessable patients with androgen-independent disease who were enrolled onto an open, randomized trial of liarozole versus prednisone. The extent of skeletal involvement was assessed by scoring each scan using the BSI and independently according to the number of metastatic lesions. The relationship of the scored bone involvement to other known prognostic factors was explored in single- and multiple-variable analyses. RESULTS: In single-variable analyses, the pretreatment factors found to be associated with survival were age (P = .0446), performance status (P = .0005), baseline prostate-specific antigen (P = .0001), hemoglobin (P = .0001), alkaline phosphatase (P = .0002), AST (P = .0021), lactate dehydrogenase (P = .0001), and treatment (P = .0098). The extent of osseous disease was significant using both the BSI (P = .0001) and the number of lesions present (P = .0001). In multiple-variable proportional hazards analyses, only BSI, age, hemoglobin, lactate dehydrogenase, and treatment arm were associated with survival. When the patient population was divided into three equal groups, with BSI values of < 1.4%, 1.4% to 5.1%, and > 5.1%, median survivals of 18.3, 15.5, and 8.1 months, respectively, were observed (P = .0079). CONCLUSION: The BSI quantifies the extent of skeletal involvement by tumor. It allows the identification of patients with distinct prognoses for stratification in clinical trials. Further study is needed to assess the utility of serial BSI determinations in monitoring treatment effects. The BSI may be particularly useful in the evaluation of agents for which prostate-specific antigen changes do not reflect clinical outcomes accurately. (+info)

Biochemical markers of bone turnover in breast cancer patients with bone metastases: a preliminary report. (6/5419)

BACKGROUND: Some biochemical markers of bone turnover are expected to reflect the disease activity of metastatic bone tumor. In the present study six biochemical markers were evaluated to determine appropriate markers for the detection of metastatic bone tumors from breast cancer (BC). METHODS: A panel of bone turnover markers was assessed in 11 normocalcemic patients with bone metastases from BC and in 19 BC patients without clinical evidence of bone metastases. Bone formation was investigated by measuring serum bone isoenzyme of alkaline phosphatase (BALP), osteocalcin (OC) and carboxy-terminal propeptide of type I procollagen (PICP): Bone resorption was investigated by measuring serum carboxy-terminal telopeptide of type I collagen (ICTP), fasting urinary pyridinoline (Pyr) and deoxypyridinoline (D-Pyr). RESULTS: PICP was influenced by age and menopausal status. Significant correlations were observed between each of bone turnover markers except between BALP and OC. The mean levels of the six bone turnover markers were higher in patients with bone metastases than in those without them and significance was observed except for OC. The best diagnostic efficiency by receiver-operating characteristic (ROC) analysis was provided by ICTP followed by Pyr or D-Pyr, BALP, PICP and OC and significance was observed between ICTP and OC. Multiple logistic regression analysis adjusted by age revealed that the only significant marker related to bone metastases was ICTP. CONCLUSIONS: Serum ICTP appears to be the leading marker of bone metastases from BC. However, to reveal the clinical usefulness of these markers, further examination will be needed to account for the ease and cost-effectiveness of the measurements. (+info)

Phase I trial of the combination of daily estramustine phosphate and intermittent docetaxel in patients with metastatic hormone refractory prostate carcinoma. (7/5419)

BACKGROUND: To apply our preclinical findings of cytotoxic synergy with the combination of estramustine phosphate (EP) and docetaxel as the basis of treatment of hormone refractory metastatic prostate cancer in man. To determine the optimal dosage and the toxicities of these two agents for future trials. PATIENTS AND METHODS: Seventeen patients with hormone refractory metastatic prostate cancer who were ambulatory with performance status < or = 2, normal marrow, renal and hepatic function were entered. Prior exposure to EP or a taxane were exclusion factors. EP was given orally at a dose of 14 mg/kg of body weight daily with concurrent docetaxel administered every 21 days as an intravenous infusion over 1 hour with dexamethasone 8 mg. PO BID for five days. EP dosages were kept static; docetaxel dosages were explored in a minimum of three patients per level for dosages of 40, 60, 70, and 80 mg/m2. Patients were evaluated weekly. Prostate specific antigen (PSA) was measured every three weeks. RESULTS: Five patients were entered at a docetaxel dose of 40 mg/m2, three at 60 mg/m2, six at 70 mg/m2, and three at 80 mg/m2. Only one patient had received prior chemotherapy. Grades 1 or 2 hypocalcemia and hypophosphatemia were seen at all dosage levels. Other grade 2 or less toxicities not related to dosage included alopecia, anorexia, stomatitis, diarrhea, and epigastric pain. Dose limiting toxicities (DLT) as grade 4 leukopenia and grade 4 fatigue were seen at 80 mg/m2. The phase II dose was defined at 70 mg/m2 with rapidly reversible leukopenia and minor liver function abnormalities. At this dosing level, dose intensity was 88% and 86% over consecutive cycles for docetaxel and EP, respectively. Two vascular events occurred at this dose level (70 mg/m2): one arterial and the other venous. PSA decreases greater than 50% from baseline were seen in 14 of 17 patients at all dosage levels. Four of the 17 patients demonstrated a complete biochemical response (PSA < or = 4 ng/ml). One patient had a partial response with measurable lung and liver lesions. CONCLUSION: EP given continuously with every three-week docetaxel at a dose of 70 mg/m2 is tolerable with evidence of antitumor activity based upon significant declines in PSA in the majority of patients and improvement of lung metastasis in one patient. Larger phase II studies of this combination in a homogenous population are warranted. (+info)

Treatment of localized primary non-Hodgkin's lymphoma of bone in children: a Pediatric Oncology Group study. (8/5419)

PURPOSE: The treatment of primary lymphoma of bone (PLB) in children has traditionally included radiotherapy to the primary site; more recently, it has included systemic chemotherapy. Because of concern about the untoward effects of treatment in a disease that is curable, we attempted to determine whether radiotherapy can be safely excluded from treatment. PATIENTS AND METHODS: The results of three consecutive Pediatric Oncology Group (POG) studies were examined to determine the impact on outcome of radiotherapy as adjunctive treatment in children and adolescents receiving chemotherapy for early-stage primary lymphoma of bone. RESULTS: From 1983 to 1997, 31 patients with localized PLB were entered onto POG studies of early-stage non-Hodgkin's lymphoma (NHL). Between 1983 and 1986, seven patients were treated with 8 months of chemotherapy with irradiation (XRT) of the primary site. After 1986, patients were treated without XRT; four received 8 months of chemotherapy, and 20 received 9 weeks of chemotherapy. Primary sites were the femur (nine), tibia (eight), mandible (five), mastoid (one), maxilla (one), zygomatic arch (one), rib (one), clavicle (one), scapula (one), ulna (one), talus (one), and calcaneous (one). Histologic classification revealed 21 cases of large cell lymphoma, five cases of lymphoblastic lymphoma, two cases of small, noncleaved-cell lymphoma, and three cases of NHL that could not be classified further. One patient relapsed at a distant site 22 months after completion of therapy. There have been no deaths. CONCLUSION: Localized PLB is curable in most children and adolescents with a 9-week chemotherapy regimen of modest intensity, and radiotherapy is an unnecessary adjunct. (+info)

CS1 maint: discouraged parameter (link) Coley, William (1949). Neoplasms of Bone. New York: Medical Book Department of Harper ... Dashiell visited Coley after suffering from a hand injury which he soon discovered to be an aggressive bone tumor. Treatment ... McCarthy, Edward (2006). "The Toxins of William B. Coley and the Treatment of Bone and Soft-Tissue Sarcomas". The Iowa ... William Bradley Coley (January 12, 1862 - April 16, 1936) was an American bone surgeon and cancer researcher best known for his ...

https://en.wikipedia.org/wiki/William_Coley

Coley, William (1949). Neoplasms of Bone. New York: Medical Book Department of Harper & Brothers. pp. 565-570.. ... McCarthy, Edward F., MD, "The Toxins of William B. Coley and the Treatment of Bone and Soft-Tissue Sarcomas". Iowa Orthopedic ... William Bradley Coley (January 12, 1862 - April 16, 1936) was an American bone surgeon and cancer researcher best known for his ... McCarthy, Edward (2006). "The Toxins of William B. Coley and the Treatment of Bone and Soft-Tissue Sarcomas". The Iowa ...

https://en.m.wikipedia.org/wiki/William_Coley

Altered expression of cell cycle regulatory proteins in benign and malignant bone and soft tissue neoplasms. „In Vivo". 21 (5 ... Bone Cancer Version 2.2016. „NCCN", 2016. *PG. Casali, JY. Blay, A. Bertuzzi, S. Bielack i inni. Bone sarcomas: ESMO Clinical ... Osteosarcoma in Paget's disease of bone. „J Bone Miner Res". 21 Suppl 2, s. P58-63, Dec 2006. DOI: 10.1359/jbmr.06s211. PMID: ... a b c d e Andrew L. Folpe, Carrie Y. Inwards: Bone and Soft Tissue Pathology: A Volume in the Foundations in Diagnostic ...

https://pl.wikipedia.org/wiki/Kostniakomięsak

Oliveira AM, Chou MM (January 2014). "USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular ... Horvai TE, Link TM (2012). Bone and soft tissue pathology (1st ed.). Philadelphia, Pa.: Elsevier/Saunders. ISBN 978-1-4377-2520 ...

https://en.wikipedia.org/wiki/Nodular_fasciitis

Due to thin bone and weak barriers, the neoplasm can extend into the sinonasal passages, pterygomaxillary fossa and eventually ... Smaller mandibular neoplasms have been enucleated where the cavity of the tumour is curetted, allowing preservation of the bone ... Recurrence within a bone graft (following resection of the original tumor) does occur, but is less common. Seeding to the bone ... Preferable removal includes 10mm of normal bone around the neoplasm. Larger ameloblastomas can require partial resection of the ...

https://en.wikipedia.org/wiki/Ameloblastoma

Myeloid neoplasms always concern bone marrow cell lineage and are related to hematopoietic cells. Myeloid tissue can also be ... Myeloid tissue, in the bone marrow sense of the word myeloid (myelo- + -oid), is tissue of bone marrow, of bone marrow cell ... Yuan J, Nguyen CK, Liu X, Kanellopoulou C, Muljo SA (2012). "Lin28b reprograms adult bone marrow hematopoietic progenitors to ... lineage, or resembling bone marrow, and myelogenous tissue (myelo- + -genous) is any tissue of, or arising from, bone marrow; ...

https://en.wikipedia.org/wiki/Myeloid_tissue

Effect of Sr90 Upon Life Span and Neoplasms of Bone and the Blood-forming Tissues. Miriam P. Finkel, Birute O. Biskis, and ... Delayed effects of bone-seeking radionuclides (Ed. Mays, C.W., et al.). 417. Finkel, M. P., Biskis, B. O., & Jinkins, P. B. ( ... Finkel, M. P., Biskis, B. O., & Scribner, G. M. (1958). The influence of strontium-90 upon life span and neoplasms of mice (No ... 1960). Illinois bone tumor death certificate study. Annual report-Division of Biological and Medical Research. Argonne National ...

https://en.wikipedia.org/wiki/Miriam_Posner_Finkel

... is an uncommon osteoid tissue-forming primary neoplasm of the bone. It has clinical and histologic manifestations ... of all primary bone tumors and only 14% of benign bone tumors making it a relatively rare form of bone tumor.[citation needed] ... Bone scintigraphy (bone scan) demonstrates abnormal radiotracer accumulation at the affected site, substantiating clinical ... Therefore, bone scans are useful only in conjunction with other radiologic studies and are not best used alone.[citation needed ...

https://en.wikipedia.org/wiki/Osteoblastoma

Leukaemias are subdivided into lymphoid and myeloid neoplasms, depending on which bone marrow cells are cancerous. The myeloid ... In adults, blood cells are formed in the bone marrow, by a process that is known as haematopoiesis. In CMML, there are ... Bone marrow core biopsies may show a predominance of myelocytic and monocytic cells, abnormal localisation of immature ... The FAB criteria for diagnosis are as follows: Monocyte count >1x109/L 0-19% blasts in bone marrow 1x109/L No Philadelphia ...

https://en.wikipedia.org/wiki/Chronic_myelomonocytic_leukemia

The myeloproliferative neoplasms (MPNs), previously myeloproliferative diseases (MPDs), are a group of diseases of the bone ... Although not a malignant neoplasm like other cancers, MPNs are classified within the hematological neoplasms. There are four ... According to the WHO Classification of Hematopoietic and Lymphoid Neoplasms 2008 myeloproliferative neoplasms are divided into ... All MPNs arise from precursors of the myeloid lineages in the bone marrow. The lymphoid lineage may produce similar diseases, ...

https://en.wikipedia.org/wiki/Myeloproliferative_disease

While chondrosarcoma is the most common form of a secondary malignant bone neoplasm found in cases of Ollier disease, other ... Early detection and consistent and repeated monitoring is important in order to prevent and treat any potential bone neoplasms ... Clinical and radiological evaluations are conducted in order to detect the presence of bone neoplasms or lesions typically ... Abnormal bone growth such as shortening or thickening and deformity may be observed in patients of Ollier disease. These bone ...

https://en.wikipedia.org/wiki/Ollier_disease

... and a number of neoplasms of the bone marrow. Causes of increased breakdown include genetic conditions such as sickle cell ... Signs of severe anemia in human bones from 4000 years ago have been uncovered in Thailand. Janz TG, Johnson RL, Rubenstein SD ( ... In manual examination, activity of the bone marrow can also be gauged qualitatively by subtle changes in the numbers and the ... Even where the source of blood loss is obvious, evaluation of erythropoiesis can help assess whether the bone marrow will be ...

https://en.wikipedia.org/wiki/Anemia

... is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. It may ... Bone marrow transplants are rarely undertaken in people with polycythemia; since this condition is non-fatal if treated and ... In the past, injection of radioactive isotopes (principally phosphorus-32) was used as another means to suppress the bone ... red cell mass arterial oxygen saturation abdominal ultrasound serum erythropoietin level bone marrow aspirate and trephine ...

https://en.wikipedia.org/wiki/Polycythemia_vera

Other embolizations are also performed for symptom relief or prior to surgery to reduce bleeding Bone Cancer: bone metastases ... such as osteoporosis or underlying neoplasm. Analogous to vertebroplasty, the purpose of sacroplasty is to provide ... to stabilize the bone. These treatments may be palliatively for bone metastases pain or for some cases such as osteoid osteoma ... A needle is placed through the skin and into the bone under CT guidance and a polymethylmethacrylate mixture is injected into ...

https://en.wikipedia.org/wiki/Interventional_radiology

Overall survival prognosis is about 30%. Deaths due to malignant neoplasms of the bones and joints account for an unknown ... usually associated with an underlying bone pathology such as Paget's disease of bone. Osteosarcoma is the most common bone ... Large doses of Sr-90, nicknamed bone seeker, increases the risk of bone cancer and leukemia in animals and is presumed to do so ... The tumor causes a great deal of pain, and can even lead to fracture of the affected bone. As with human osteosarcoma, bone ...

https://en.wikipedia.org/wiki/Osteosarcoma

In cases of a supposed myeloid neoplasm, a bone marrow biopsy will be performed utilizing cytogenetic analysis. This type of ... A bone marrow aspirate may be utilized to confirm an increase in basophils or significantly high numbers of precursors to the ... Elevation of basophils may also be representative of multiple other underlying neoplasms such as polycythemia vera (PV), ... The root cause of basophilia can be determined through a bone marrow biopsy, genetic testing to look for genetic mutations, or ...

https://en.wikipedia.org/wiki/Basophilia

However, it is controversial whether it represents a true neoplasm or rather a developmental disorder of growing bone. ... They originate from the growth plate, and are located in adjacent parts of the metaphysis and diaphysis of long bones, most ... No treatment is needed in asymptomatic patients and spontaneous remission with replacement by bone tissue is to be expected. ... A nonossifying fibroma is a common benign bone tumor in children and adolescents. ...

https://en.wikipedia.org/wiki/Nonossifying_fibroma

T-Cell Lymphoblastic Leukemia (T-ALL) is a type of acute lymphoblastic leukemia with aggressive malignant neoplasm of the bone ... Bone marrow consists of a combination of solid and liquid components. Bone marrow aspiration and biopsies are typically done ... Acute Lymphoblastic Leukemia (ALL) is a condition where immature white blood cells accumulate in the bone marrow, subsequently ... Patients often present extensive bone marrow involvement, mediastinal mass, adenopathy, CNS involvement, and splenomegaly. ...

https://en.wikipedia.org/wiki/T-Cell_Acute_Lymphoblastic_Leukemia

A phosphaturic mesenchymal tumor is an extremely rare benign neoplasm of soft tissue and bone that inappropriately produces ... Rowe, PS; de Zoysa, PA; Dong, R; Wang, HR; White, KE; Econs, MJ; Oudet, CL (Jul 2000). "MEPE, a new gene expressed in bone ... Adult patients have worsening myalgias, bone pains and fatigue which are followed by recurrent fractures. Children present with ... Jun 2007). "Cinacalcet in the management of tumor-induced osteomalacia". Journal of Bone and Mineral Research. 22 (6): 931-37. ...

https://en.wikipedia.org/wiki/Oncogenic_osteomalacia

It may also occur with fractures of the facial bones, neoplasms, during asthma attacks, when the Heimlich maneuver is used, and ...

https://en.wikipedia.org/wiki/Subcutaneous_emphysema

Occasionally, a bone metastasis of a GCCL could potentially be mistaken for a primary giant-cell tumor of bone - interestingly ... Spivach A, Borea B, Bertoli G, Daris G (July 1976). "[Primary lung neoplasm of rare incidence: giant cell carcinoma]". Minerva ... Pai SB, Lalitha RM, Prasad K, Rao SG, Harish K (September 2005). "Giant cell tumor of the temporal bone-a case report". BMC Ear ... The new paradigm recognizes that lung cancers are a large and extremely heterogeneous family of malignant neoplasms, with over ...

https://en.wikipedia.org/wiki/Giant-cell_carcinoma_of_the_lung

... tracheal neoplasms MeSH C04.588.448.200 - bone marrow neoplasms MeSH C04.588.531.500 - mammary neoplasms, experimental MeSH ... skull base neoplasms MeSH C04.588.149.828 - spinal neoplasms MeSH C04.588.180.260 - breast neoplasms, male MeSH C04.588.180.390 ... bile duct neoplasms MeSH C04.588.274.120.250.250 - common bile duct neoplasms MeSH C04.588.274.120.401 - gallbladder neoplasms ... femoral neoplasms MeSH C04.588.149.721 - skull neoplasms MeSH C04.588.149.721.450 - jaw neoplasms MeSH C04.588.149.721.450.583 ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C04)

... pseudogout Neoplasms Neurovascular disorders Bone and cartilage disorders Extraarticular disorders Bursitis/Tendinitis of the ... Epigenetics in Bone and Joint Disorders. Medical Epigenetics. Boston: Academic Press. pp. 295-314. doi:10.1016/B978-0-12-803239 ... Bone, Spine : Revue du Rhumatisme. 81 (2): 118-24. doi:10.1016/j.jbspin.2014.01.001. PMID 24556284. Janeways: "immunology" ...

https://en.wikipedia.org/wiki/Rheumatism

... bone marrow neoplasms MeSH C15.378.420.155 - anemia, sickle cell MeSH C15.378.420.155.440 - hemoglobin sc disease MeSH C15.378. ... bone marrow neoplasms MeSH C15.378.190.625 - myelodysplastic syndromes MeSH C15.378.190.625.062 - anemia, refractory MeSH ... splenic neoplasms MeSH C15.604.744.742 - splenic rupture MeSH C15.604.744.742.500 - splenosis MeSH C15.604.744.909 - ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C15)

Macrosomia Macroglossia Advanced bone age Organomegaly Neonatal hypoglycemia Neoplasms Congenital diaphragmatic hernia ( ... One of the most noted features of OGS is the increased risk of neoplasms in certain OGSs. SGBS in particular has been found to ... Limb patterning and skeletal development may also go awry when GCP3 mutations inhibit regulations of responses to bone ...

https://en.wikipedia.org/wiki/Simpson–Golabi–Behmel_syndrome

The skull bone structure can also be subject to a neoplasm that by its very nature reduces the volume of the intracranial ... Neoplasms will often show as differently colored masses (also referred to as processes) in CT or MRI results. ... "CNS and Miscellaneous Intracranial and Intraspinal Neoplasms" (PDF). SEER Pediatric Monograph. National Cancer Institute. pp. ... More generally a neoplasm may cause release of metabolic end products (e.g., free radicals, altered electrolytes, ...

https://en.m.wikipedia.org/wiki/Brain_tumors

The skull bone structure can also be subject to a neoplasm that by its very nature reduces the volume of the intracranial ... "CNS and Miscellaneous Intracranial and Intraspinal Neoplasms" (PDF). SEER Pediatric Monograph. National Cancer Institute. pp. ... More generally a neoplasm may cause release of metabolic end products (e.g., free radicals, altered electrolytes, ... Due to the BBB, cancerous cells of a primary neoplasm cannot enter the bloodstream and get carried to another location in the ...

https://en.m.wikipedia.org/wiki/Brain_tumor

... a malignant neoplasm of bone and articular cartilage of limbs ICD-10 code C40-8W, C40-8, C40-9 and C40-9W, diesel locos ...

https://en.wikipedia.org/wiki/C40

... a malignant neoplasm of bone Open Scripting Architecture, for AppleScript Open Services Access, a set of standards for mobile ...

https://en.wikipedia.org/wiki/Osa

... will learn in depth about the pathology and treatment of various forms of primary benign and malignant neoplasms of the bones ... to the bones, which is much more common; these specialists deal mostly with primary bone tumors). The physician will study ... Due to the relative rarity of primary bone tumor in relation to other forms of cancer, there are fewer than two hundred ... it is advisable when confronted with primary malignancy of the bone to seek out the treatment of an orthopedic oncologist, due ...

https://en.wikipedia.org/wiki/Orthopedic_oncologist

Recently they have been shown to reside for much longer periods in the bone marrow as long-lived plasma cells (LLPC). They ... Plasmacytoma, multiple myeloma, Waldenström macroglobulinemia and plasma cell leukemia are malignant neoplasms ("cancer") of ... After leaving the bone marrow, the B cell acts as an antigen presenting cell (APC) and internalizes offending antigens, which ... Plasma cells originate in the bone marrow; B cells differentiate into plasma cells that produce antibody molecules closely ...

https://en.wikipedia.org/wiki/Plasma_cells

Bind bones and other tissues to each other. Alpha polypeptide chains. tendon, ligament, skin, cornea, cartilage, bone, blood ... Connective tissue neoplasms including sarcomas such as hemangiopericytoma and malignant peripheral nerve sheath tumor in ... Special connective tissue consists of reticular connective tissue, adipose tissue, cartilage, bone, and blood.[8] Other kinds ... cartilage and bone.[15]:158 Cells of the immune system, such as macrophages, mast cells, plasma cells and eosinophils are found ...

https://en.m.wikipedia.org/wiki/Fibrous_connective_tissue

Several severe adverse health effects, such as an increased incidence of cancers, thyroid diseases, CNS neoplasms, and possibly ... As studies of biological samples (including bone, thyroid glands and other tissues) have been undertaken, it has become ...

https://en.wikipedia.org/wiki/Downwinders

Bone tumor. C. *The Cancer Council Australia. *Cancer of unknown primary origin ... Salivary gland neoplasm. *Sarcoma. *Skin cancer. *Small intestine cancer. *Small-cell carcinoma ...

https://simple.wikipedia.org/wiki/Category:Cancer

... bone marrow - bone marrow suppression - booster - branched DNA assay - breakthrough infection - Broadway Cares/Equity Fights ... neoplasm - nephrotoxic - neuralgia - neurological complications of AIDS - neuropathy - neutralization - neutralizing antibody ...

https://en.m.wikipedia.org/wiki/Index_of_AIDS-related_topics

ද්‍රව තරල පිටතට ගෙන පරීක්‍ෂා කිරීම(Bone Marrow Biopsy FNAC) වැනි පරීක්‍ෂණ මගින් පිළිකා කල් තබා හදුනා ගත හැක. ... Malignant tumor, malignant neoplasm. A coronal CT scan showing a malignant mesothelioma. Legend: → tumor ←, ✱ central pleural ...

https://si.wikipedia.org/wiki/පිළිකා

Neoplasms 60% increase in death rate 60% increased death rate from neoplasms. In 1999-2003, neoplasms accounted for 17% of all ... I had to come to the somewhat uncomfortable conclusion that even Andrew Bolt was becoming Indigenous because the bones of his ... is that people have a connection with their ancestors whose bones are in the soil. Whose dust is part of the sand. ...

https://en.m.wikipedia.org/wiki/Indigenous_Australians

The fibrous connective tissue that connects bones to other bones and is also known as articular ligament, articular larua, ...

https://en.m.wikipedia.org/wiki/Glossary_of_biology

In experiments, it new bone fully covered skull wounds in test animals and stimulated growth in human bone marrow stromal cells ... Neoplasm: Tumor suppressor genes/proteins and Oncogenes/Proto-oncogenes. Ligand. Growth factors. ... A non-viral PDGF "bio patch" can regenerate missing or damaged bone by delivering DNA in a nano-sized particle directly into ... Repairing bone fractures, fixing craniofacial defects and improving dental implants are among potential uses. The patch employs ...

https://en.wikipedia.org/wiki/Platelet-derived_growth_factor

The radioisotopes travel selectively to areas of damaged bone, and spare normal undamaged bone. Isotopes commonly used in the ... Hypopituitarism commonly develops after radiation therapy for sellar and parasellar neoplasms, extrasellar brain tumours, head ... Total body irradiation (TBI) is a radiation therapy technique used to prepare the body to receive a bone marrow transplant. ... Patients receiving palliative radiation to treat uncomplicated painful bone metastasis should not receive more than a single ...

https://en.wikipedia.org/wiki/Radiation_therapy

"Islet Cell Tumors of the Pancreas / Endocrine Neoplasms of the Pancreas". The Sol Goldman Pancreas Cancer Research Center. ... See page 95 for citation regarding "... lesser degree of involvement of bones and brain and other anatomical sites." ... Farrell JJ, Fernández-del Castillo C (juni 2013). "Pancreatic cystic neoplasms: management and unanswered questions". ... "ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms of the digestive system: Well ...

https://da.m.wikipedia.org/wiki/Bugspytkirtelkræft

Bridges, M.; Jones, A. M. E.; Bones, A. M.; Hodgson, C.; Cole, R.; Bartlet, E.; Wallsgrove, R.; Karapapa, V. K.; Watts, N.; ... Tse, G; Eslick, G.D. (2014). "Cruciferous vegetables and risk of colorectal neoplasms: a systematic review and meta-analysis". ...

https://en.m.wikipedia.org/wiki/Glucosinolates

Other less common sites of origin include the prostate, kidney, thyroid, skin, colon and blood or bone marrow. ... Eye neoplasms can affect all parts of the eye, and can be a benign tumor or a malignant tumor (cancer). Eye cancers can be ... Retrieved from "https://en.wikipedia.org/w/index.php?title=Eye_neoplasm&oldid=895356793" ...

https://en.m.wikipedia.org/wiki/Eye_neoplasm

Bone scans should reveal osteoblastic appearance due to increased bone density in the areas of bone metastasis-opposite to what ... "Male Genitals - Prostate Neoplasms". Pathology study images. University of Virginia School of Medicine. Archived from the ... The most common symptom is bone pain, often in the vertebrae (bones of the spine), pelvis, or ribs. Spread of cancer into other ... a bone scan look for spread to the bones, and endorectal coil magnetic resonance imaging to closely evaluate the prostatic ...

https://fa.wikipedia.org/wiki/سرطان_پروستات?match=en

"CNS and Miscellaneous Intracranial and Instraspinal Neoplasms" (PDF). SEER Pediatric Monograph. National Cancer Institute. pp ...

https://kn.wikipedia.org/wiki/ಮೆದುಳಿನ_ಕ್ಯಾನ್ಸರ್_ಗೆಡ್ದೆ

B21.) Human Immunodeficiency Virus (HIV) disease Resulting in malignant neoplasms *(B21.0) HIV disease resulting in Kaposi's ... A18.0) Tuberculosis of bones and joints. *(A18.1) Tuberculosis of genitourinary system ... B21.3) HIV disease resulting in other malignant neoplasms of lymphoid, haematopoietic and related tissue ...

https://hi.wikipedia.org/wiki/आइसीडी-१०_अध्याय_ब

Also, bone marrow depression (inducing leukopenia and thrombocytopenia) and acute kidney and liver failure have been reported. ... Folate deficiency hinders DNA synthesis and cell division, affecting hematopoietic cells and neoplasms the most because of ...

https://en.wikipedia.org/wiki/Vitamin_b9

ISBN 0-7020-2606-9. Huete-Garin, A.; S.S. Sagel (2005). "Chapter 6: "Mediastinum", Thymic Neoplasm". In J.K.T. Lee; S.S. Sagel ... In the two lobes, hematopoietic precursors from the bone-marrow, referred to as thymocytes, mature into T cells. Once mature, T ... Cells in the thymus can be divided into thymic stromal cells and cells of hematopoietic origin (derived from bone marrow ... Schwarz, B. A.; Bhandoola, A. (2006). "Trafficking from the bone marrow to the thymus: a prerequisite for thymopoiesis". ...

https://en.wikipedia.org/wiki/Thymus

Bone pain, joint pain (caused by the spread of "blast" cells to the surface of the bone or into the joint from the marrow ... "The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia". Blood. 127 (20): ... A bone marrow biopsy provides conclusive proof of ALL, typically with ,20% of all cells being leukemic lymphoblasts.[27] A ... These lymphoblasts build up in the bone marrow and may spread to other sites in the body, such as lymph nodes, the mediastinum ...

https://en.m.wikipedia.org/wiki/Acute_lymphoblastic_leukemia

神經母細胞瘤（Neuroblastoma）是一種在特定神經組織中形成的癌症。它最常從一側腎上腺開始，但也可以在頸部、胸部、腹部或脊髓中發展。[1]症狀包括骨痛（英语：bone pain）、腹部、頸部或胸部腫塊，或皮膚下無痛的藍色腫

https://zh.wikipedia.org/wiki/神經母細胞瘤

Large cell lung carcinoma (LCLC) is a heterogeneous group of undifferentiated malignant neoplasms originating from transformed ... Signs of more advanced cases include bone pain, nervous system changes (headache, weakness, dizziness, balance problems, ... in that the tumor cells lack light microscopic characteristics that would classify the neoplasm as a small-cell carcinoma, ... most typically with brain imaging and or scans of the bones.[32] ...

https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma

... as a type of myeloproliferative neoplasm, a group of cancers in which there is abnormal growth of cells in the bone marrow. ... A bone marrow biopsy will reveal collagen fibrosis, replacing the marrow that would normally occupy the space.[citation needed] ... Primary myelofibrosis (PMF) is a rare bone marrow blood cancer.[1] It is classified by the World Health Organization (WHO) ... The bone marrow in a typical case is hypercellular and diffusely fibrotic. Both early and late in disease, megakaryocytes are ...

https://en.m.wikipedia.org/wiki/Myelofibrosis

Neoplasm CD34[1] Stromelysin-3[10] Factor XIIIa[6] Dermatofibroma - + + Dermatofibrosarcoma protuberans + - - ...

https://en.wikipedia.org/wiki/Benign_fibrous_histiocytoma

Krumbhaar EB (1919). "Role of the blood and the bone marrow in certain forms of gas poisoning". JAMA. 72: 39-41. doi:10.1001/ ... Secondary neoplasm[edit]. Development of secondary neoplasia after successful chemotherapy or radiotherapy treatment can occur ... In very severe myelosuppression, which occurs in some regimens, almost all the bone marrow stem cells (cells that produce white ... Virtually all chemotherapeutic regimens can cause depression of the immune system, often by paralysing the bone marrow and ...

https://en.wikipedia.org/wiki/Chemotherapeutics

"Neoplasms and cancer" has been chosen to reflect the fact that not all tumours are benign. The word "cancer" has been included ... The above documentation is transcluded from ಟೆಂಪ್ಲೇಟು:Bone and cartilage navs/doc. (edit , history). Editors can experiment in ...

https://kn.wikipedia.org/wiki/ಟೆಂಪ್ಲೇಟು:Central_nervous_system_navs

Osteoporotic bone marrow defect. *Paget's disease of bone. *Periapical abscess *Phoenix abscess ... Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...

https://en.wikipedia.org/wiki/Lupus_erythematosus–lichen_planus_overlap_syndrome

Bone marrow-derived cells that normally mature in the bloodstream ⇨ leukemia. *Bone marrow-derived cells that normally mature ... 8560-8580) Complex epithelial neoplasms. Carcinoma In situ[edit]. The term carcinoma in situ (or CIS) is a term for cells that ... and imaging studies in a logical fashion to obtain information about the size of the neoplasm and the extent of its invasion ... or other notable characteristics consistent with a more highly differentiated neoplasm. ...

https://en.wikipedia.org/wiki/Carcinomas

It can also involve bone marrow transplantation. Information on prognosis is limited by the rarity of the condition. Prognosis ... myeloproliferative neoplasms, chemotherapy for other cancers or exposure to toxins were defined as secondary AEL. These cases ... Acute erythroid leukemias can be classified as follows: 50% or more of all nucleated bone marrow cells are erythroblasts, ... Orazi, Attilio; O'Malley, Dennis P.; Arber, Daniel A. (2006-07-20). Illustrated Pathology of the Bone Marrow. Cambridge ...

https://en.wikipedia.org/wiki/Acute_erythroid_leukemia

endocrine bone disease: Osteitis fibrosa cystica (Brown tumor). infectious bone disease: Osteomyelitis (Sequestrum, Involucrum ... Fibrous dysplasia (Monostotic, Polyostotic) · Skeletal fluorosis · bone cyst (Aneurysmal bone cyst) · Hyperostosis (Infantile ... "Bone. 30 (2): 368-76. doi:10.1016/S8756-3282(01)00685-8. PMID 11856644.. Unknown parameter ,month=. ignored (help)CS1 maint: ... "Decision rules for selecting women for bone mineral density testing: application in postmenopausal women referred to a bone ...

https://kn.wikipedia.org/wiki/ಆಸ್ಟಿಯೊಪೊರೋಸಿಸ್‌

... By Erik L. Ridley, AuntMinnie staff writer. January 21, 2015 -- ... biopsy of bone neoplasms yields similar accuracy to CT-guided biopsy for evaluating primary and metastatic bone lesions, while ... set out to compare the diagnostic accuracy of ultrasound-guided biopsy with CT-guided biopsy for primary and metastatic bone ...

https://www.auntminnie.com/index.aspx?sec=log&URL=https:%2F%2Fwww.auntminnie.com%2Findex.aspx%3Fsec%3Dlog%E2%8A%82%3Dpas%E2%88%A8iginalURL%3Dhttps:%252F%252Fwww.auntminnie.com%252Findex.aspx%253Fsec%253Dnws%2526sub%253Drad%2526pag%253Ddis%2526itemId%253D109836

Pfizer is currently recruiting for the NCT00381095 Bone Neoplasms, Intractable Pain, Cancer Cancer trial. Review trial ...

https://www.pfizer.com/science/find-a-trial/nct00381095

... malignant bone neoplasms in dogs were much more prevalent than the benign ones, (2); OS were the most prevalent bone neoplasms ... of all malignant bone neoplasms observed in this study. Other malignant bone neoplasms diagnosed, in descending order of ... Clinical signs associated with primary bone neoplasms depend much more on the location than on the type of the neoplasm itself ... Osteosarcoma was the most prevalent bone tumor, accounting for 86.7% of all malignant primary bone neoplasms diagnosed. Most ...

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2012001200018&lng=en&tlng=en

... changes in the bone marrow (BM) stroma might arise from pressure exerted by the neoplastic clone in shaping a supportive ... The bone marrow stroma in hematological neoplasms--a guilty bystander Nat Rev Clin Oncol. 2011 Mar 29;8(8):456-66. doi: 10.1038 ... In the setting of hematological neoplasms, changes in the bone marrow (BM) stroma might arise from pressure exerted by the ... The role of bystander BM stromal elements in the setting of hematological neoplasms is discussed, strengthening the rationale ...

https://pubmed.ncbi.nlm.nih.gov/21448151/?dopt=Abstract

Bone marrow niche / extracellular matrix disruption in myeloproliferative neoplams. Myeloproliferative neoplasm-associated bone ... Bone marrow niche dysregulation in myeloproliferative neoplasms Message Subject (Your Name) has forwarded a page to you from ... Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow. J Exp Med. 2015;212(5):759-774. ... Direct or indirect targeting of the bone marrow niche in myeloproliferative neoplasms: is there a role?. To date, the only ...

http://www.haematologica.org/content/105/5/1189

The concept does not refer to neoplasms located in bones. ... Neoplasms composed of bony tissue, whether normal or of a soft ... Tissue Neoplasms, Bone; Neoplasms, Bone Tissue; Bony Tissue Neoplasms; Neoplasms, Bony Tissue; Bone Tissue Neoplasm; Bony ... Tissue Neoplasm; Neoplasm, Bone Tissue; Neoplasm, Bony Tissue; Tissue Neoplasm, Bone; Tissue Neoplasm, Bony; Tissue Neoplasms, ... Bone Tissue Neoplasms (Tissue Neoplasms, Bone). Subscribe to New Research on Bone Tissue Neoplasms ...

http://www.curehunter.com/public/keywordSummaryD018213-Bone-Tissue-Neoplasms-Tissue-Neoplasms--Bone.do

Mineralized bone was also lost. The cytokine CCL3, known to be involved in bone loss, was increased in AML cells in mice and ... The normal bone marrow anatomy (here using the example of the femur) is composed of different types of bone, blood vessels and ... It was shown that PTHinduced bone remodeling led to a release of su-praphysiological levels of TGFβ1 from the bone matrix ... A hostel for the hostile: the bone marrow niche in hematologic neoplasms ...

https://haematologica.org/article/view/7550

ICD-9 code 213.6 for Benign neoplasm of pelvic bones sacrum and coccyx is a medical classification as listed by WHO under the ... Benign neoplasm of pelvic bones sacrum and coccyx (213.6). ICD-9 code 213.6 for Benign neoplasm of pelvic bones sacrum and ... coccyx is a medical classification as listed by WHO under the range -BENIGN NEOPLASMS (210-229).. ...

https://www.aapc.com/codes/icd9-codes/213.6

ICD-9 code 198.5 for Secondary malignant neoplasm of bone and bone marrow is a medical classification as listed by WHO under ... Secondary malignant neoplasm of bone and bone marrow (198.5). ICD-9 code 198.5 for Secondary malignant neoplasm of bone and ... bone marrow is a medical classification as listed by WHO under the range -MALIGNANT NEOPLASM OF OTHER AND UNSPECIFIED SITES ( ...

https://www.aapc.com/codes/icd9-codes/198.5

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.. W S Pear, ... Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. ... Using a bone marrow reconstitution assay with cells containing retrovirally transduced TAN1 alleles, we analyzed the oncogenic ... Moreover, the murine tumors caused by TAN1 in the bone marrow transplant model are very similar to the TAN1-associated human ...

http://jem.rupress.org/content/183/5/2283?ijkey=a06392ead9eef6ba7b1ccf9bbcbda4dec7b4c308&keytype2=tf_ipsecsha

Bone Fracture Risk Increased in Patients With Myeloproliferative Neoplasms Susan Moench, PhD, PA-C ... Close more info about Bone Fracture Risk Increased in Patients With Myeloproliferative Neoplasms ... Close more info about Bone Fracture Risk Increased in Patients With Myeloproliferative Neoplasms ... Close more info about Bone Fracture Risk Increased in Patients With Myeloproliferative Neoplasms ...

https://www.oncologynurseadvisor.com/home/cancer-types/myeloproliferative-neoplasms/risk-of-bone-fracture-greater-in-pts-with-mpn/

Standards Reporting Form: Bone Marrow Synoptic Reporting for Hematologic Neoplasms - CAP US ...

https://g-i-n.net/document-store/standards-reporting-forms/cap-us/standards-reporting-form-cap-bone-marrow-synoptic-reporting-hematologic-neoplasms/view

Metastatic tumour of bone Metastatic tumor of bone Secondary cancer of bone Secondary malignant neoplasm of bone and bone ... Synonyms - Secondary malignant neoplasm of bone Metastatic malignant neoplasm to bone Secondary malignant neoplasm of bone ( ... ICD-10 Code C79.5 Secondary malignant neoplasm of bone and bone marrow SNOMED-CT Term Secondary malignant neoplasm of bone ( ... Bone Metastases (39). Management of metastatic cancer deposits in bone MeSH Search Term "Neoplasm Metastasis"[mesh] ...

http://www.orthopaedicweblinks.com/OCOSH_Classification/Orthopaedic_Oncology/index.html

Trisacryl gelatin microspheres versus polyvinyl alcohol particles in the preoperative embolization of bone neoplasms. - Antonio ... Trisacryl gelatin microspheres versus polyvinyl alcohol particles in the preoperative embolization of bone neoplasms.. Abstract ... in the preoperative embolization of bone neoplasms, on the basis of intraoperative blood loss quantified by the differences in ... From January 1997 to December 2002, preoperative embolization of bone tumors (either primary or secondary) was carried out in ...

http://www.curehunter.com/public/pubmed15383854.do

long bones (M9261/3) - see Neoplasm, bone, malignant. *. malignant (M9310/3) 170.1. *. jaw (bone) (lower) 170.1. *. upper 170.0 ... Home > 2015 ICD-9-CM Diagnosis Codes > Neoplasms 140-239 > Benign Neoplasms 210-229 > Benign neoplasm of bone and articular ... adenomatoid (M9054/0) - see also Neoplasm, by site, benign*. odontogenic (M9300/0) 213.1*. upper jaw (bone) 213.0. ... Fibroma (M8810/0) - see also Neoplasm, connective tissue, benign*. ameloblastic (M9330/0) 213.1*. upper jaw (bone) 213.0. ...

http://www.icd9data.com/2015/Volume1/140-239/210-229/213/213.1.htm

... neoplasms. Learn vocabulary, terms, and more with flashcards, games, and other study tools. ... muscles and bones, skin, Fluids and electrolytes, reproductive, genetics, ... inflammation/immune, blood, muscles and bones, skin, Fluids and electrolytes, reproductive, genetics, neoplasms. ... bone pain. weight loss and fatigue. fever. enlarged lymph nodes, spleen, and liver. *if leukemic cells infiltrte the central ...

https://quizlet.com/145835848/inflammationimmune-blood-muscles-and-bones-skin-fluids-and-electrolytes-reproductive-genetics-neoplasms-flash-cards/

... ... in patients with bone metastases (BM). In neuroendocrine neoplasms (NEN), BM are a negative prognostic factor, however tend to ... in Patients with Bone Metastases of Neuroendocrine Neoplasms. Introduction: Antiresorptive therapy (ART) with bisphosphonates ... Keywords: bone metastases, skeletal related event, survival, bisphosphonates, 68Ga-PET, 18FDG-PET, CT scan ...

https://www.enets.org/bone-metastases-and-skeletal-related-events-in-patients-with-neuroendocrine-neoplasms-nen-the-role-of-zoledronic-acid.html

Stephen Oh discuss their views on when and why patients should have a bone marrow biopsy. ... How often should MPN patients have a bone marrow biopsy? Dr. Brady Stein and Dr. ... How often should MPN patients have a bone marrow biopsy? Dr. Brady Stein and Dr. Stephen Oh discuss their views on bone marrow ... Also, we look to see how actionable a bone marrow might be. Am I going to respond to it? Am I going to change your therapy? Am ...

https://www.patientpower.info/video/how-often-should-mpn-patients-have-a-bone-marrow-biopsy

Benign neoplasm of bones of skull and face. 2016 2017 2018 2019 2020 Billable/Specific Code *D16.4 is a billable/specific ICD- ... Benign neoplasm of bone and articular cartilage. 2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code Type 1 Excludes*benign ... Benign neoplasm of lower jaw bone. 2016 2017 2018 2019 2020 Billable/Specific Code Applicable To*Keratocyst of mandible ... Benign neoplasm of lower jaw bone. 2016 2017 2018 2019 2020 Billable/Specific Code Applicable To*Keratocyst of mandible ...

https://www.icd10data.com/ICD10CM/Codes/C00-D49/D10-D36/D16-/D16.4

D16.0 Benign neoplasm of scapula and long bones of upper limb D16.00 Benign neoplasm of scapula and long bones of unspecified ... Benign neoplasm of short bones of left upper limb. 2016 2017 2018 2019 2020 Billable/Specific Code *D16.12 is a billable/ ... Benign neoplasm, short bone of left arm. ICD-10-CM D16.12 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0): *564 ... Benign neoplasm of bone and articular cartilage. 2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code Type 1 Excludes*benign ...

https://www.icd10data.com/ICD10CM/Codes/C00-D49/D10-D36/D16-/D16.12

Dynamic contact problems in bone neoplasm analyses and the primal-dual active set (PDAS) method. (English). In: Brandts, J., ... In the contribution growths of the neoplasms (benign and malignant tumors and cysts), located in a system of loaded bones, will ... Because the geometry of the system of loaded and possible fractured bones with enlarged neoplasms changes in time, the ... dynamic contact problems; mathematical models of neoplasms - tumors and cysts; Coulomb and Tresca frictions; variational ...

https://dml.cz/handle/10338.dmlcz/702974

Secondary malignant neoplasm of bone and bone marrow information including symptoms, causes, diseases, symptoms, treatments, ... Bone and bone *Malignant neoplasm *Bone marrow *Bone marrow symptoms *Bone marrow disease *Bone marrow disorder *Malignant * ... Neoplasm (16 causes) *Neoplasm pain *Bone Hierarchical classifications of Secondary malignant neoplasm of bone and bone marrow ... Secondary malignant neoplasm of bone and bone marrow: Related Topics. These medical condition or symptom topics may be relevant ...

https://www.rightdiagnosis.com/medical/secondary_malignant_neoplasm_of_bone_and_bone_marrow.htm

Build: Wed Jun 21 18:33:50 EDT 2017 (commit: 4a3b2dc). National Center for Advancing Translational Sciences (NCATS), 6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-435-0888. ...

https://pharos.nih.gov/idg/diseases/umls:C0206639

... metabolic bone disease, metastatic neoplasms, mri, osteoporosis, pain, physical therapy, primary bone neoplasms, radiography, ...

https://www.orthopaedicclinic.com.sg/tag/primary-bone-neoplasms/

Subsequent primary neoplasms among bone sarcoma survivors; increased risks remain after 30 years of follow-up and in the latest ...

http://www.nature.com/bjc/?error=cookies_not_supported&code=dab8b0de-6fa6-4638-9952-ddc33b14b894

... in order to get rid of the primary bone cancer, medicine used surgery, sometimes, including amputation of affected limbs. Today ... Treatment of primary bone neoplasms. Long ago, in order to get rid of the primary bone cancer, medicine used surgery, sometimes ... There are few types of primary bone tumors (based on bone cancer symptoms and outpatient examination), from which depends the ... you can remove only affected zone and replace it with a bone implant, plastic, metal or with the help of new method - benign ...

http://bonecancersymptoms.org/2009/01/the-treatment-of-primary-bone-cancer/

Carla nasceu em Viana do Castelo em 1977. Licenciada em Anatomia Patológica, Citológica e Tanatológica pela Escola Superior de Tecnologia da Saúde em Lisboa. Concluiu a certificação em Laboratory Management pela ASCP (American Association of Clinical Pathology) em Setembro de 2016. Mestre em Genética Molecular e Biomedicina pela Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa. Trabalhou no Centro Hospitalar Lisboa Central entre 1998 e 2015, exercendo histopatologia e imunohistoquímica, sendo co-responsável pelo sector. Trabalha no Dr. Joaquim Chaves, Laboratório de Anatomia Patológica desde 2004 onde exerce funções de Coordenação Técnica e da Qualidade.. ...

https://pathologika.com/bone-marrow-synoptic-reporting-for-hematologic-neoplasms-guideline/

Patient - Neoplasm Bone Tumour. Summary. *Bone tumours in the foot account for less than 2% of all bone tumours, and ... Most heel bone tumours are discovered on xray for other unrelated conditions. ... Benign tumours may require surgical excision and a period of recovery for bone strengthening. ... They can become painful if they cause enlargement of the bone or fractures. ...

https://healthfirstsoutham.yourfootpain.co.uk/2018/11/14/patient-neoplasm-bone-tumour/

Evidence-based guideline provides a framework for a synoptic format for clear bone marrow reporting to advance patient ... The evidence-based guideline "Bone Marrow Synoptic Reporting for Hematologic Neoplasms" provides a framework for a synoptic ... Considering the possible ancillary studies that could be ordered on a bone marrow specimen, which ones are required on a ... The guideline tackles the complexities of the bone marrow organ and establishes an evidence-based framework that laboratories ...

https://www.cap.org/protocols-and-guidelines/cap-guidelines/current-cap-guidelines/bone-marrow-synoptic-reporting-for-hematologic-neoplasms

However, the role of ,i,RTEL1,/i, mutations in other bone marrow failure (BMF) syndromes and myeloid neoplasms, and the ... Heterozygous RTEL1 variants in bone marrow failure and myeloid neoplasms Judith C W Marsh 1 2 , Fernanda Gutierrez-Rodrigues 3 ... Heterozygous RTEL1 variants in bone marrow failure and myeloid neoplasms Judith C W Marsh et al. Blood Adv. 2018. . ... However, the role of RTEL1 mutations in other bone marrow failure (BMF) syndromes and myeloid neoplasms, and the contribution ...

https://phgkb.cdc.gov/PHGKB/phgHome.action?action=forward&dbsource=huge&id=160826

Objectives: To compare histopathological and clinical findings of metastasis to the temporal bone with previous reports and to determine the prevalence of these metastases in patients with nonsystemic cancer. (elsevier.com)
These were evaluated histopathologically for metastasis to and site of involvement within the temporal bone, and histological characteristics of the tumor. (elsevier.com)
Moreover, the patients who have bone metastasis at presentation are even rare. (symptoma.com)
Radiation therapy can help to relieve localized pain due to bone metastasis. (symptoma.com)
This study will explore the biologic activity of guanabenz in reducing bone turn over in solid tumor patients with bone metastasis. (clinicaltrials.gov)
Bone metastasis give rise to major complications that lead to significant morbidity and impairment of life quality. (clinicaltrials.gov)
The most common primary for bone metastasis is prostate, lung and breast carcinoma. (clinicaltrials.gov)
The primary objective is to compare the diagnostic performance of 18F- Fluoride PET/CT scanning to that of conventional bone scanning for detecting cancer that has spread to the bone (bone metastasis). (clinicaltrials.gov)
Nylen CO Cancer metastasis in the temporal bone simulating acute inflammation in the middle ear. (jamanetwork.com)
Bone metastasis is cancer that starts in one area and then spreads to a bone. (drugs.com)
What is bone metastasis? (drugs.com)
Your risk for bone metastasis is higher if you have had cancer for a long time. (drugs.com)
What are the signs and symptoms of bone metastasis? (drugs.com)
How is bone metastasis treated? (drugs.com)
What can I do to manage my bone metastasis? (drugs.com)
In breast cancer, bone is the second most common site of metastatic spread, and 90% of patients dying of breast cancer have bone metastasis. (bioportfolio.com)
Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. (genecards.org)
Solitary bone metastasis of unknown origin may pose a diagnostic challenge, and should be considered a potential primary tumor until proven otherwise. (wheelessonline.com)

A retrospective study of necropsy and biopsy cases of 90 primary bone tumors (89 malignant and one benign) in dogs received over a period of 22 years at the Laboratório de Patologia Veterinária, Universidade Federal de Santa Maria, was performed. (scielo.br)
Generally, they are aggressive tumors, with local bone destruction, invasion of adjacent soft tissues, and high metastatic potential (Dernell et al. (scielo.br)
The presumptive diagnosis of primary bone tumors in dogs involves several aspects such as age, breed, anatomical location, and radiological appearance of the lesion. (scielo.br)
Moreover, the murine tumors caused by TAN1 in the bone marrow transplant model are very similar to the TAN1-associated human tumors and suggest that TAN1 may be specifically oncotropic for T cells. (rupress.org)
Benign and malignant tumors affecting bone, cartilage, muscle or other soft tissue of the limbs and axial skeleton. (orthopaedicweblinks.com)
2903 Bone Metastases (BM) in Neuroendocrine Tumors (NET): Imaging Characteristics and Clinical Implications. (enets.org)
For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned. (icd10data.com)
In the contribution growths of the neoplasms (benign and malignant tumors and cysts), located in a system of loaded bones, will be simulated. (dml.cz)
There are few types of primary bone tumors (based on bone cancer symptoms and outpatient examination ), from which depends the type of surgery and radiotherapy. (bonecancersymptoms.org)
Bone tumors may be malignant or benign. (symptoma.com)
Benign bone tumors are generally asymptomatic , whereas progressive bone pain at the site of the lesion, accompanied by swelling and typically occurring during the night or at rest, is characteristic for bone sarcomas [3] [5]. (symptoma.com)
Irregular borders of identified lesions, areas of bone destruction and extension into soft tissues are main signs of malignant tumors, while sharply demarcated lesions may be suggestive of benign tumor growth [3]. (symptoma.com)
In fact, a lack of clinical suspicion is the primary reason why bone tumors are diagnosed late [3]. (symptoma.com)
The literature describes eight types of benign bone tumors - osteoma, benign giant cell tumor, osteoid osteoma , osteoblastoma , osteochondroma, aneurysmal bone cyst , fibrous dysplasia and enchondroma [2]. (symptoma.com)
On the basis of their morphological characteristics, bone tumors can be bone-forming, cartilage-forming, or fibrous tissue forming [6]. (symptoma.com)
It is estimated that approximately 3,300 new cases of malignant bone and joint tumors will appear in the United States yearly and on the basis of these findings, they are one of the rarest groups of malignancies encountered in clinical practice [7]. (symptoma.com)
Tumors of the temporal bone and skull base tend to arise in one of three locations: (1) the mastoid or middle ear, (2) the jugular foramen, or (3) the petroclival junction or petrous apex. (mhmedical.com)
Proctor BLindsay JR Tumors involving the petrous pyramid of the temporal bone. (jamanetwork.com)
Maddox HE Metastatic tumors of the temporal bone. (jamanetwork.com)
Schuknecht HFAllam AFMurakami Y Pathology of secondary malignant tumors of the temporal bone. (jamanetwork.com)
Jahn AFFarkashidy JBerman JM Metastatic tumors in the temporal bone: a pathophysiologic study. (jamanetwork.com)
Belal A Metastatic tumors of the temporal bone: a histological report. (jamanetwork.com)
Nelson EGHinojosa R Histopathology of metastatic temporal bone tumors. (jamanetwork.com)
Adams GLPaparella MMel-Fiky FM Primary and metastatic tumors of the temporal bone. (jamanetwork.com)
Malignant tumors of bone. (medlineplus.gov)
An x-ray, CT, or MRI may be used to check your bones for tumors. (drugs.com)
bone tumors Up to Fifty (50) patients will be recruited in this feasibility study. (bioportfolio.com)
Breast and prostate cancer metastasize to bone most frequently, which reflects the high incidence of both these tumors, as well as their prolonged clinical courses. (bioportfolio.com)
Tumors or cancer located in bone tissue or specific BONES. (bioportfolio.com)
Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. (healthtap.com)
Enchondromas constitute 3-10% of all bone tumors and 12-24% of benign bone tumors. (medscape.com)
[ 2 ] and 9% of all bone tumors. (medscape.com)
they represent four to thirteen percent of all primary bone tumors. (wheelessonline.com)
In order of frequency, the most prevalent benign tumors of the spine are osteoblastomas, aneurysmal bone cysts and osteoid osteomas. (wheelessonline.com)
Radiology is central in the management of patients with suspected primary bone tumors. (wheelessonline.com)

Osteosarcoma was the most prevalent bone tumor, accounting for 86.7% of all malignant primary bone neoplasms diagnosed. (scielo.br)
Temporal bone metastases were not observed in cases where the primary tumor was adequately treated. (elsevier.com)
Absence of temporal bone involvement in cases in which the primary tumor was adequately treated stresses the need for early management of cancer. (elsevier.com)
pain was a bone tumor. (symptoma.com)
Bone sarcomas, primarily osteosarcoma and Ewing sarcoma are malignant forms and the pathogenesis primarily includes genetic mutations that cause aberrant growth and formation of tumor cells. (symptoma.com)
A bone tumor, (also spelled bone tumour), is a neoplastic growth of tissue in bone. (icd.codes)
Micrograph of an osteosarcoma, a malignant primary bone tumor. (icd.codes)
Right, Higher magnification of the same temporal bone showing tumor (T) in the mastoid (M) (hematoxylin-eosin, original magnification ×50). (jamanetwork.com)
Tumor (T) had invaded most of the temporal bone (hematoxylin-eosin, original magnification ×4). (jamanetwork.com)
Ewing sarcoma is a malignant bone tumor that forms in the bone or soft tissue. (medlineplus.gov)
The tumor often spreads ( metastasizes) to the lungs and other bones. (medlineplus.gov)
Children may also break a bone at the site of the tumor after a minor injury. (medlineplus.gov)
The largest bone tumor center in China. (cancerindex.org)
[4] Dashiell visited Coley after suffering from a hand injury which he soon discovered to be an aggressive bone tumor. (wikipedia.org)
What is its relation with bone tumor? (healthtap.com)
A bone tumor is a type of neoplasm. (healthtap.com)
A bone tumor is more specific and tells us more information. (healthtap.com)
1 CM pituitary neoplasm, stable but has been called tumor, hypophysitis, nothing, leading to $1ks of mris with no certainty as to diagnosis of pituitary or partial adrenal insuff, biopsy worth risks? (healthtap.com)
neoplasms of uncertain behavior" means a rare tumor that the pathologist cannot say with certainty either is or is not cancer . (healthtap.com)
Osteochondroma is the most common benign bone tumor. (medscape.com)
Atlas of Genetics and Cytogenetics in Oncology and Haematology (AGCOH) Adamantinoma of long bones is a low-grade, malignant biphasic tumor, characterized by a variety of morphological patterns, most commonly epithelial cells, surrounded by a relatively bland spindle-cell osteo-fibrous component. (orthopaedicweblinks.com)
Adamantinoma - 1o bone tumor with predilection for tibial diaphysis presenting during early adulthood Signs & Symptoms: - painful masses with variable symptom duration ranging from few months to few years Xrays: - well-circumscribed, eccentric, lytic lesions of tibial diaphysis - may be multicystic lesion with surrounding sclerosis - expansion of bone +/- intact cortex but no. (orthopaedicweblinks.com)
Oncologic pain is related to the tumor itself: it can be secondary to the release of chemical mediators, increased pressure within the bone, micro-fractures, stretching of the periosteum, or reactive muscle spasms. (wheelessonline.com)
Neurological deficits occur when the neural elements are compressed by either the tumor or by retropulsed bone fragments from a pathological fracture. (wheelessonline.com)
The main differential diagnosis of a primary bone tumor is metastatic disease, which is significantly more common. (wheelessonline.com)

The incidence of bone metastases (BM) in patients with NENs is 12-25%, and skeletal related events (SREs) occur in up to 21% of affected cases. (enets.org)
Antiresorptive therapy (ART) with bisphosphonates or denosumab is effective in preventing skeletal-related events (SREs) in patients with bone metastases (BM). (enets.org)
Transcatheter-Arterial embolization (TAE) is an established regional, palliative treatment option for liver metastases in patients (pts) with neuroendocrine neoplasms (NENs). (enets.org)
Up to 73% of patients with neuroendocrine neoplasms (NEN) present with distant metastases at diagnosis. (enets.org)
Bone metastases (BM) are usually reported in less than 10% of patients. (enets.org)
Results: Of 212 patients with primary nondisseminated malignant neoplasms, 47 had metastases to the temporal bone (76 temporal bones). (elsevier.com)
Conclusions: In the largest series to date, we found temporal bone metastases more frequently than previously reported. (elsevier.com)
These three have the highest cancer incidence in the USA with up to 85% prevalence of bone metastases at the time of death. (clinicaltrials.gov)
Clinical trials of HIFU in bone metastases have indicated that the method is safe and gives an effective reduction of patient pain. (clinicaltrials.gov)
Morton ALButler SAKhan AJohnson AMiddleton P Temporal bone metastases: pathophysiology and imaging. (jamanetwork.com)
Current treatments for patients with bone metastases are primarily palliative and include localized therapies (radiation and surgery), systemic therapies (chemotherapy, hormonal therapy, radiopharmaceutical, and bisphosphonates although the primary goal of the use of these therapies are often to address the disease itself), and analgesics (opioids and non-steroidal anti-inflammatory drugs). (bioportfolio.com)
Recently, radiofrequency ablation has been tested as a treatment option for bone metastases [8]. (bioportfolio.com)
A palliative treatment for painful bone metastases that is non-invasive, without long-term toxicity and having minimal complications would be a useful tool for treating physicians and also a beneficial option for patients suffering from painful bone metastases. (bioportfolio.com)
Results of preliminary studies indicate that ExAblate treatment of painful bone metastases may be a beneficial treatment option [14, 15]. (bioportfolio.com)
The categories that have been provided for the classification of malignant neoplasms distinguish between those that are stated or presumed to be primary (originate in) of the particular site or types of tissue involved, those that are stated or presumed to be secondary (deposits, metastases, or spread from a primary elsewhere) of specified sites, and malignant neoplasms without specification of site. (cdc.gov)

Its specific role in the pathogenesis, response to therapy, and transformation of myeloproliferative neoplasms has only recently been explored. (haematologica.org)
Niche functionality is likely affected not only by the genomic background of the myeloproliferative neoplasm-associated mutated hematopoietic stem cells, but also by disease-associated 'chronic inflammation', and subsequent adaptive and innate immune responses. (haematologica.org)
In this timely article, we will review current knowledge surrounding the deregulated bone marrow niche in myeloproliferative neoplasms and suggest how this may be targeted, either directly or indirectly, potentially influencing therapeutic choices both now and in the future. (haematologica.org)
Philadelphia chromosome negative' myeloproliferative neoplasms (MPN) are a group of relatively rare hematologic diseases characterized by a clonal proliferation of blood cells, most commonly secondary to acquired hematopoietic stem cell (HSC) mutations that directly or indirectly induce upregulation of the JAK-STAT pathway. (haematologica.org)
Results of a retrospective analysis showed a significantly elevated risk of bone fractures in a population-based cohort of patients with myeloproliferative neoplasms (MPNs) , particularly polycythemia vera (PV), compared with the overall population. (oncologynurseadvisor.com)

Osteosarcoma (OS) is considered the most common primary bone neoplasm in dogs. (scielo.br)
The most common types of primary bone tumour are osteosarcoma and Ewing's sarcoma, both of which are most frequently diagnosed in children and young adults. (cancerindex.org)
Buzzoword on bone biopsy with osteosarcoma? (brainscape.com)

D16.20 is a billable code used to specify a medical diagnosis of benign neoplasm of long bones of unspecified lower limb. (icdlist.com)
To code a diagnosis of this type, you must use one of the three child codes of C40.0 that describes the diagnosis 'malignant neoplasm of scapula and long bones of upper limb' in more detail. (icd.codes)
Most often, it starts in the long bones of the arms and legs, the pelvis, or the chest. (medlineplus.gov)
It usually presents before the onset of puberty and is often located within the long bones. (medscape.com)
Osteochondromas most commonly occur in the hands and feet, and enchondromas typically involve the iliac crests and metaphyses of long bones. (medscape.com)
It is characterized by skeletal anomalies (short stature, platyspondyly, short broad ilia) and enchondromas in the long bones or pelvis. (medscape.com)
What benign bone neoplasms can present on the metaphysis of long bones? (brainscape.com)
Adamantinoma of long bones: clinical, pathological and ultrastructural features. (orthopaedicweblinks.com)
Adamantinoma of the long bones is a rare, low-grade malignant neoplasm of unknown histogenesis, which affects mainly the tibia of young adults (Keeney et al. (orthopaedicweblinks.com)
Abstract Adamantinoma is a rare tumour of long bones whose pathogenesis is unknown. (orthopaedicweblinks.com)

January 21, 2015 -- Ultrasound-guided biopsy of bone neoplasms yields similar accuracy to CT-guided biopsy for evaluating primary and metastatic bone lesions, while saving money, offering patient convenience, and avoiding radiation dose, according to research from the Henry Ford Health System. (auntminnie.com)
The researchers set out to compare the diagnostic accuracy of ultrasound-guided biopsy with CT-guided biopsy for primary and metastatic bone lesions. (auntminnie.com)
How Often Should MPN Patients Have a Bone Marrow Biopsy? (patientpower.info)
Dr. Brady Stein and Dr. Stephen Oh discuss their views on bone marrow biopsy as it relates to prognosis and treatment. (patientpower.info)
And in most cases, for ET nowadays, we do need to do a bone marrow biopsy to establish the diagnosis. (patientpower.info)
But when we are able to make a diagnosis officially based on valid criteria, then we discuss the option of a bone marrow biopsy. (patientpower.info)
Now, when I offer a bone marrow biopsy, of course, that's not really an offer that many people will take. (patientpower.info)
If I think the character of your disease is changing, if I think after 15 years of ET or PV, and I'm seeing something different, and I'm suspecting that it's making its movement or transformation into a new entity, then I need a bone marrow biopsy to make that diagnosis. (patientpower.info)
We retrospectively analyzed the bone marrow biopsy of two MPNs cohorts of patients with polycythemia (PV) (n=64) and non-PV patients [including essential thrombocythemia (ET), and early/prefibrotic primary myelofibrosis (PMF)] (n=222). (unicatt.it)
Open up in another screen Fig. 3 CT guided-needle biopsy demonstrating the lytic bone tissue lesion from the talus. (synbiosci.com)
Open up in another screen Fig. 5 Intraoperative bone tissue biopsy with fluoroscopy, disclosing lytic lesion on talus. (synbiosci.com)
Bone marrow biopsy: interpretive guidelines for the surgical pathologist. (springer.com)
Morice WG, Kurtin PJ, Hodnefield JM, Shanafelt TD, Hoyer JD, Remstein ED, Hanson CA. Predictive value of blood and bone marrow flow cytometry in B-cell lymphoma classification: comparative analysis of flow cytometry and tissue biopsy in 252 patients. (springer.com)
Chronic myelomonocytic leukemia: The role of bone marrow biopsy immunohistology. (springer.com)

Finally, it provides the rationale for a "two-pronged" approach, directly targeting cancer cells themselves while also targeting the bone microenvironment to make it inhospitable to malignant cells and, ultimately, eradicating cancer stem-like cells. (haematologica.org)
Symptoms of bone cancer, treatment and types. (bonecancersymptoms.org)
Long ago, in order to get rid of the primary bone cancer, medicine used surgery, sometimes, including amputation of affected limbs. (bonecancersymptoms.org)
The Pathology and Laboratory Quality Center (the Center) of the College of American Pathologists (CAP) has advanced blood cancer diagnostics by developing recommendations to standardize the basic components of a synoptic report template for bone marrow samples. (cap.org)
As the cancer dissolves the bone, it breaks easily. (symptoma.com)
Cancer that starts in a bone is uncommon. (icdlist.com)
Cancer that has spread to the bone from another part of the body is more common. (icdlist.com)
The most common symptom of bone cancer is pain. (icdlist.com)
Surgery is often the main treatment for bone cancer. (icdlist.com)
Because bone cancer can come back after treatment, regular follow-up visits are important. (icdlist.com)
What Is Bone Cancer? (medlineplus.gov)
How Is Bone Cancer Diagnosed? (medlineplus.gov)
How Is Bone Cancer Staged? (medlineplus.gov)
What Are the Risk Factors for Bone Cancer? (medlineplus.gov)
What Happens After Treatment for Bone Cancer? (medlineplus.gov)
What's New in Bone Cancer Research and Treatment? (medlineplus.gov)
The purpose of this trial is to prove whether Zoledronic acid combine radiotherapy can reduce radiotherapy dose in treatment of non-small cell lung cancer bone metastasis'pain relief or not. (clinicaltrials.gov)
The trial will accrue four hundred-eighty eight (488) evaluable patients with breast cancer, prostate cancer or lung cancer (approximately 163 of each cancer type) referred for routine bone scanning by their respective physicians. (clinicaltrials.gov)
NCCN clinical practice guidelines in oncology (NCCN guidelines): Bone cancer. (medlineplus.gov)
Cancer that spreads to a bone can weaken the bone and increase your risk for fractures. (drugs.com)
Smoking increases your risk for new or returning cancer, and can cause bone loss. (drugs.com)
Cancer can prevent new bone from forming, or create extra bone. (drugs.com)
Bone cancer can cause the bone to dissolve and release stored calcium. (drugs.com)
Treatment will depend on the type of cancer that spread to a bone. (drugs.com)
For example, if you had breast cancer that spread to a bone, you will need treatment used for breast cancer. (drugs.com)
Medicine may be given to reduce bone pain, slow damage caused by the cancer, or prevent the cancer from causing the bone to fracture. (drugs.com)
In contrast, secondary bone cancer is where the cancer started in another part of the body but has then spread to the bones. (cancerindex.org)
Other less common types of bone cancer include: Chondrosarcoma (a cancer arising in cartilage cells, usually found in adults between ages 50-75, though the less common mesenchymal-chondrosarcoma is more frequent in younger patients), Malignant Fibrous Histiocytoma of bone (MFH), Chondoma (a rare low grade malignancy occuring mostly between ages 30 -70), and other rare tumours. (cancerindex.org)
BCRT became a registered the charity in 2006 and raises funds for research into primary bone cancer, and provides information and support for patients and their families. (cancerindex.org)
William Bradley Coley (January 12, 1862 - April 16, 1936) was an American bone surgeon and cancer researcher best known for his early contributions to the study of cancer immunotherapy . (wikipedia.org)
Please would like to know what is meant by thyroid shows well defined follicular neoplasm composed of cells with granular cyloplasm, is it cancer? (healthtap.com)
A malignant neoplasm of the liver means cancer . (healthtap.com)
You need to know the nature of the neoplasm (a generic name saying it is likely cancer but you need to know what kind of cancer it might be). (healthtap.com)
Fanconi anemia (FA) is an inherited bone marrow failure syndrome characterized by chromosomal fragility, progressive marrow failure, and cancer predisposition. (bloodjournal.org)
Diseases associated with MRC2 include Primary Bone Cancer and Gliofibroma . (genecards.org)

68Ga-DOTA-TATE PET/CT plays an important role in neuroendocrine neoplasm(NEN)diagnosis and biological charecteristcs evaluation.Skeleton is the second common metastatic organ in NEN after liver and it affects the quality of patient's life. (enets.org)
And then if you do have one as a baseline from the beginning of your diagnosis, how often do you recommend bone marrow biopsies after? (patientpower.info)
For myelofibrosis, you have to have a bone marrow to make a diagnosis. (patientpower.info)
For polycythemia vera, the diagnosis can be made without a bone marrow. (patientpower.info)
C40.31 is a billable code used to specify a medical diagnosis of malignant neoplasm of short bones of right lower limb. (icdlist.com)
dental or fixture trauma, or a current or prior diagnosis of osteonecrosis of the jaw (ONJ), of exposed bone in the mouth, or of slow healing after dental procedures. (knowcancer.com)

Less well understood, but of growing interest, is the interaction between cells in the bone marrow during the initiation, maintenance and treatment of hematologic neoplasms. (haematologica.org)
The evidence-based guideline " Bone Marrow Synoptic Reporting for Hematologic Neoplasms " provides a framework for a synoptic format for clear, appropriate bone marrow reporting to advance patient safety and treatment of hematopoietic disorders. (cap.org)
The guideline includes nine statements to assist pathologists in producing complete and clear synoptic reports for hematologic neoplasms. (cap.org)
Diagnostic criteria are based on the 2008 WHO classification of hematologic neoplasms. (springer.com)

In order to determine the appropriate code for each reported neoplasm, a number of factors must be taken into account including the morphological type of neoplasm and qualifying terms. (cdc.gov)

What does "238.0 neoplasm of uncertain behavior of bone and articular cartilage" mean on a babies discharge papers? (healthtap.com)

A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. (icd10data.com)
Open in a separate windows Fig. 1 A remote avulsion lesion of the tip of the remaining lateral malleolus mentioned having a well corticated bone tissue fragment. (synbiosci.com)
An MRI performed at the moment showed a well-circumscribed lesion from the talar throat with reactive bone tissue marrow edema (Fig. 2). (synbiosci.com)
Frontal radiograph of the right hand demonstrates a lytic expansile lesion in the fifth metacarpal bone, with thinning of the cortex that has a somewhat scalloped appearance. (medscape.com)
The lesion involves the diaphysis and approaches the end of the bone near the metacarpophalangeal joint. (medscape.com)
Because of pain, the lesion was curetted and packed with morselized allograft bone. (medscape.com)

In dogs, unlike what is seen in humans and in some other species of domestic animals, malignant bone neoplasms are much more prevalent than benign neoplasms (Brodey 1979, Misdorp 1980, Dorfman et al. (scielo.br)

Neoplasms composed of bony tissue, whether normal or of a soft tissue which has become ossified. (curehunter.com)
Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified ( C25.9 ). (icd10data.com)
To evaluate the tolerance for and effectiveness of carbon ion radiotherapy in patients with unresectable bone and soft tissue sarcomas. (nih.gov)
Fifty-seven patients with 64 sites of bone and soft tissue sarcomas not suited for resection received carbon ion radiotherapy. (nih.gov)
Carbon ion radiotherapy seems to be a safe and effective modality in the management of bone and soft tissue sarcomas not eligible for surgical resection, providing good local control and offering a survival advantage without unacceptable morbidity. (nih.gov)
Iced section analysis uncovered spindle cells admixed with large cells, fibrous tissues, and bone tissue. (synbiosci.com)
Bone and soft tissue pathology (1st ed. (wikipedia.org)

The Cemento-ossifying fibroma (COF) is a benign fibro-osseous neoplasm of odontogenic origin, that is preferentially localized in the molar and premolar mandibular area. (scielo.cl)

Multiple myeloma is a malignant disease usually originating in the bone marrow, although other tissues may be involved. (chiro.org)
They are differentiated from neoplasms composed of bone marrow cells, such as MULTIPLE MYELOMA. (bioportfolio.com)

Clinical signs associated with primary bone neoplasms depend much more on the location than on the type of the neoplasm itself (Jongeward 1985). (scielo.br)
The plethora of ongoing clinical trials will hopefully translate into improved treatments options for patients suffering from bone metastatic cancers. (symptoma.com)
The administered radioactivity will be determined based on the sites routine clinical practice for conventional bone imaging. (clinicaltrials.gov)
Page : 57-8 Surana SS, Mogra NK, Dube MK, Dhruva AK Adamantinoma of tibia is a rarely encountered neoplasm of dispute histogenesis and variable clinical. (orthopaedicweblinks.com)

Left, Left temporal bone of a 52-year-old man who had transitional cell carcinoma of the urinary bladder. (jamanetwork.com)
Left, Right temporal bone of a 61-year-old man who had undifferentiated carcinoma of the lungs. (jamanetwork.com)
Left temporal bone of a 37-year-old woman who had follicular carcinoma of the thyroid. (jamanetwork.com)
Separate categories are provided in ICD-10 for coding malignant primary and secondary neoplasms (C00-C96), carcinoma in situ (D00-D09), benign neoplasms (D10-D36), and neoplasms of uncertain or unknown behavior (D37-D48). (cdc.gov)

However, the role of RTEL1 mutations in other bone marrow failure (BMF) syndromes and myeloid neoplasms, and the contribution of monoallelic RTEL1 mutations to disease development are not well defined. (cdc.gov)
one constituting unselected patients with idiopathic BMF, unexplained cytopenia, or myeloid neoplasms (n = 457) and a second cohort comprising selected patients on the basis of the suspicion of constitutional/familial BMF (n = 59). (cdc.gov)
Topics covered include myeloid neoplasms of the bone marrow, including both chronic and acute myeloid leukemias. (springer.com)
Dunphy CH, O'Malley DP, Perkins SL, Chang CC. Analysis of immunohistochemical markers in bone marrow sections to evaluate for myelodysplastic syndromes and acute myeloid leukemias. (springer.com)

Dysspondyloenchondromatosis is a nonhereditary skeletal dysplasia characterized by anisospondyly and multiple enchondromas in vertebrae and the metaphyseal and diaphyseal parts of long tubular bones, leading to kyphoscoliosis and lower limb asymmetry. (medscape.com)

ICD-9 code 213.6 for Benign neoplasm of pelvic bones sacrum and coccyx is a medical classification as listed by WHO under the range -BENIGN NEOPLASMS (210-229). (aapc.com)
ICD-9 code 198.5 for Secondary malignant neoplasm of bone and bone marrow is a medical classification as listed by WHO under the range -MALIGNANT NEOPLASM OF OTHER AND UNSPECIFIED SITES (190-199). (aapc.com)

Morphology of Blood Disorders, 2nd edition is an outstanding atlas with over 800 high-quality digital images, covering the whole spectrum of blood and bone marrow morphology, with particular emphasis on malignant haematology. (wiley.com)
The two authors, Giuseppe D Onofrio and Gina Zini, both from Catholic University of the Sacred Heart, Rome, Italy are recognized experts in the morphology of blood and bone marrow. (wiley.com)
Morphology, behavior, and site must all be considered when coding neoplasms. (cdc.gov)
Therapy effect: impact on bone marrow morphology. (elsevier.com)

As a consequence, the number of patients developing metastatic bone disease during their lifetime has also increased. (bioportfolio.com)

Percentage of Participants occur bone pain recurrence at 1 to 12 month after radiotherapy. (clinicaltrials.gov)

The bone marrow niche is a complex and dynamic structure composed of a multitude of cell types which functionally create an interactive network facilitating hematopoietic stem cell development and maintenance. (haematologica.org)
This review summarizes the emerging concepts of the normal and leukemic hematopoietic bone marrow niche. (haematologica.org)
Interest in the leukemic stem-like cell (LSC) niche in the bone marrow (BM) developed due to the major advances made in the understanding of the normal hematopoietic stem/progenitor cell (HSPC) niche over the last 15 years. (haematologica.org)
Using a bone marrow reconstitution assay with cells containing retrovirally transduced TAN1 alleles, we analyzed the oncogenic potential of both nuclear and extranuclear forms of truncated TAN1 in hematopoietic cells. (rupress.org)

Bony fusion was initiated by inserting bone grafts from the iliac crests into the titanium cage. (chiro.org)
The World Health Organization (WHO) defines osteochondroma as a cartilage-capped bony projection on the external surface of a bone. (medscape.com)
As this metaplastic cartilage is stimulated, enchondral bone formation occurs, developing a bony stalk. (medscape.com)

Osteochondroma is a benign, cartilaginous neoplasm that is found in any bone that undergoes enchondral bone formation in its development. (medscape.com)

For example, in PMF, patients may range from those lacking any discernible symptomatology to those describing debilitating constitutional symptoms, abdominal discomfort due to splenomegaly, bone pain, and symptomatic anemia, amongst others. (haematologica.org)
Methods: Autopsy records of 864 patients were screened to select those with primary nondisseminated malignant neoplasms. (elsevier.com)
Metastatic disease must be considered as a cause of hearing loss in patients with a history of malignant neoplasm. (elsevier.com)
Number of patients who had blood specimens taken to collect and evaluate markers of bone formation and bone resorption. (clinicaltrials.gov)
Objective response is defined as the patients bone pain relief reach PR(Partial remission) or CR(Complete remission).and Objective response rate is defined as Objective response patients'percentage in total patients. (clinicaltrials.gov)
RESULTS: Among 19 patients treated for NB resistant to induction therapy, 12 of 15 had complete remission (CR) of bone marrow (BM) disease, and three others who had less than partial responses achieved prolonged progression-free survival (one remains on study at 21+ months, two had PD at 12 and 17 months). (mendeley.com)
Treatment with external beam radiation therapy (EBRT) is the standard of care for patients with localized bone pain, and results in the palliation of pain for many of these patients. (bioportfolio.com)
Patients must have objective evidence of metastatic disease to bone. (knowcancer.com)

Small B-cell neoplasms with typical mantle cell lymphoma immunophenotypes often include chronic lymphocytic leukemias. (springer.com)

Anatomy10

Organisms1

Diseases17

Chemicals and Drugs6

Analytical, Diagnostic and Therapeutic Techniques and Equipment4

Phenomena and Processes6

Disciplines and Occupations1

Technology, Industry, Agriculture2

Information Science3

Health Care5

Publication Characteristics1

Relative efficacy of 32P and 89Sr in palliation in skeletal metastases. (1/5419)

A fluorescent orthotopic bone metastasis model of human prostate cancer. (2/5419)

Ibandronate reduces osteolytic lesions but not tumor burden in a murine model of myeloma bone disease. (3/5419)

Gastrin-releasing peptide receptors in the human prostate: relation to neoplastic transformation. (4/5419)

Prognostic significance of extent of disease in bone in patients with androgen-independent prostate cancer. (5/5419)

Biochemical markers of bone turnover in breast cancer patients with bone metastases: a preliminary report. (6/5419)

Phase I trial of the combination of daily estramustine phosphate and intermittent docetaxel in patients with metastatic hormone refractory prostate carcinoma. (7/5419)

Treatment of localized primary non-Hodgkin's lymphoma of bone in children: a Pediatric Oncology Group study. (8/5419)

Bone Neoplasms

Bone and Bones

Bone Remodeling

Bone Density

Bone Resorption

Bone Marrow

Bone Marrow Cells

Bone Development

Bone Diseases

Bone Regeneration

Pancreatic Neoplasms

Bone Matrix

Stromal Cells

Hematologic Neoplasms

Bone Marrow Transplantation

Hematopoietic Stem Cells

Bystander Effect

Neoplasms, Bone Tissue

Soft Tissue Neoplasms

Neoplasms, Connective and Soft Tissue

Neoplasms, Gonadal Tissue

Neoplasms, Adipose Tissue

Neoplasms, Nerve Tissue

Coccyx

Pelvic Bones

Sacrum

Porpoises

Lipoma

Anatomy, Comparative

Keratin-1

Tissue Banks

Biopsy, Fine-Needle

Sarcoma

Polyvinyl Alcohol

Gelatin

Embolization, Therapeutic

Microspheres

Iridoid Glycosides

Polyvinyls

International Classification of Diseases

Jaw

Databases, Factual

Clinical Coding

Jaw Diseases

Mandibular Neoplasms

Neuroendocrine Tumors

Webcasts

Consensus Development Conferences as Topic

Accreditation

Congresses as Topic

Carcinoma, Neuroendocrine

Diphosphonates

Relative efficacy of 32P and 89Sr in palliation in skeletal metastases. (1/5419)

A fluorescent orthotopic bone metastasis model of human prostate cancer. (2/5419)

Ibandronate reduces osteolytic lesions but not tumor burden in a murine model of myeloma bone disease. (3/5419)

Gastrin-releasing peptide receptors in the human prostate: relation to neoplastic transformation. (4/5419)

Prognostic significance of extent of disease in bone in patients with androgen-independent prostate cancer. (5/5419)

Biochemical markers of bone turnover in breast cancer patients with bone metastases: a preliminary report. (6/5419)

Phase I trial of the combination of daily estramustine phosphate and intermittent docetaxel in patients with metastatic hormone refractory prostate carcinoma. (7/5419)

Treatment of localized primary non-Hodgkin's lymphoma of bone in children: a Pediatric Oncology Group study. (8/5419)

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Doxycycline Decreases Tumor Burden in a Bone Metastasis Model of Human Breast Cancer | Cancer Research

WHATS UP DOC? Osteosarcoma is a primary bone cancer - Entertainment & Life - Norwell Mariner - Norwell, MA

WHATS UP DOC? Osteosarcoma is a primary bone cancer - Entertainment & Life - The Weston Town Crier - Weston, MA

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Symptoms of Primary Bone Cancer

EMEA (Europe, Middle East and Africa) Metastatic Bone Tumor Treatment Market Report 2017 - QY Research

Primary bone lymphoma

Primary and secondary bone lymphomas by Carlo Messina, David Christie et al.

Primary bone lymphoma of the left radius: a case report and related literature review | European Journal of Medical Research |...

Cancers | Free Full-Text | Integrin αvβ3 Signaling in Tumor-Induced Bone Disease

Bone-Targeted Therapy for Metastatic Prostate Cancer

Clinical usefulness of bisphosphonates in oncology: Treatment of bone metastases, antitumoral activity and effect on bone...

IJMS | Free Full-Text | Development of a Patient-Derived Xenograft (PDX) of Breast Cancer Bone Metastasis in a Zebrafish Model

MINERALIZED 3-D TUMOR MODELS TO STUDY BREAST CANCER BONE METASTASIS | Innovative Molecular Analysis Technologies (IMAT)

MINERALIZED 3-D TUMOR MODELS TO STUDY BREAST CANCER BONE METASTASIS | Innovative Molecular Analysis Technologies (IMAT)