Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.
Polymerized methyl methacrylate monomers which are used as sheets, moulding, extrusion powders, surface coating resins, emulsion polymers, fibers, inks, and films (From International Labor Organization, 1983). This material is also used in tooth implants, bone cements, and hard corneal contact lenses.
A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
Substances used to bond COMPOSITE RESINS to DENTAL ENAMEL and DENTIN. These bonding or luting agents are used in restorative dentistry, ROOT CANAL THERAPY; PROSTHODONTICS; and ORTHODONTICS.
The methyl esters of methacrylic acid that polymerize easily and are used as tissue cements, dental materials, and absorbent for biological substances.
Dental cements composed either of polymethyl methacrylate or dimethacrylate, produced by mixing an acrylic monomer liquid with acrylic polymers and mineral fillers. The cement is insoluble in water and is thus resistant to fluids in the mouth, but is also irritating to the dental pulp. It is used chiefly as a luting agent for fabricated and temporary restorations. (Jablonski's Dictionary of Dentistry, 1992, p159)
Procedures to repair or stabilize vertebral fractures, especially compression fractures accomplished by injecting BONE CEMENTS into the fractured VERTEBRAE.
A polymer obtained by reacting polyacrylic acid with a special anion-leachable glass (alumino-silicate). The resulting cement is more durable and tougher than others in that the materials comprising the polymer backbone do not leach out.
The maximum compression a material can withstand without failure. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p427)
The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
A relatively hard, translucent, restorative material used primarily in anterior teeth. (From Boucher's Clinical Dental Terminology, 4th ed, p50)
The methyl ester of methacrylic acid. It polymerizes easily to form POLYMETHYL METHACRYLATE. It is used as a bone cement.
Water-soluble low-molecular-weight polymers of acrylic or methacrylic acid that form solid, insoluble products when mixed with specially prepared ZnO powder. The resulting cement adheres to dental enamel and is also used as a luting agent.
The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.
Bone loss due to osteoclastic activity.
The joining of objects by means of a cement (e.g., in fracture fixation, such as in hip arthroplasty for joining of the acetabular component to the femoral component). In dentistry, it is used for the process of attaching parts of a tooth or restorative material to a natural tooth or for the attaching of orthodontic bands to teeth by means of an adhesive.
Zirconium. A rather rare metallic element, atomic number 40, atomic weight 91.22, symbol Zr. (From Dorland, 28th ed)
A compound used as an x-ray contrast medium that occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield.
The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001)
Tumors or cancer located in bone tissue or specific BONES.
Crumbling or smashing of cancellous BONE by forces acting parallel to the long axis of bone. It is applied particularly to vertebral body fractures (SPINAL FRACTURES). (Blauvelt and Nelson, A Manual of Orthopedic Terminology, 1994, p4)
The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.
Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.
Broken bones in the vertebral column.
Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.
A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapatite, beta-tricalcium phosphate, and various other biomaterials. The bone substitutes as inert materials can be incorporated into surrounding tissue or gradually replaced by original tissue.
The mechanical property of material that determines its resistance to force. HARDNESS TESTS measure this property.
Used as a dental cement this is mainly zinc oxide (with strengtheners and accelerators) and eugenol. (Boucher's Clinical Dental Terminology, 4th ed, p50)
The growth and development of bones from fetus to adult. It includes two principal mechanisms of bone growth: growth in length of long bones at the epiphyseal cartilages and growth in thickness by depositing new bone (OSTEOGENESIS) with the actions of OSTEOBLASTS and OSTEOCLASTS.
Cells contained in the bone marrow including fat cells (see ADIPOCYTES); STROMAL CELLS; MEGAKARYOCYTES; and the immediate precursors of most blood cells.
SURFACE-ACTIVE AGENTS that induce a dispersion of undissolved material throughout a liquid.
The longest and largest bone of the skeleton, it is situated between the hip and the knee.
Diseases of BONES.
Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.
A property of the surface of an object that makes it stick to another surface.
Replacement for a hip joint.
Nonexpendable items used in the performance of orthopedic surgery and related therapy. They are differentiated from ORTHOTIC DEVICES, apparatus used to prevent or correct deformities in patients.
Infections resulting from the implantation of prosthetic devices. The infections may be acquired from intraoperative contamination (early) or hematogenously acquired from other sites (late).
Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.
Procedures to restore vertebrae to their original shape following vertebral compression fractures by inflating a balloon inserted into the vertebrae, followed by removal of the balloon and injection of BONE CEMENTS to fill the cavity.
Supplies used in building.
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
Replacement of the hip joint.
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
Chemical reaction in which monomeric components are combined to form POLYMERS (e.g., POLYMETHYLMETHACRYLATE).
The grafting of bone from a donor site to a recipient site.
An adhesion procedure for orthodontic attachments, such as plastic DENTAL CROWNS. This process usually includes the application of an adhesive material (DENTAL CEMENTS) and letting it harden in-place by light or chemical curing.
Prostheses used to partially or totally replace a human or animal joint. (from UMDNS, 1999)
The administration of medication by insertion of a tiny needle or catheter into the spinal sac or epidural cavity.
The growth action of bone tissue as it assimilates surgically implanted devices or prostheses to be used as either replacement parts (e.g., hip) or as anchors (e.g., endosseous dental implants).
Characteristics or attributes of the outer boundaries of objects, including molecules.
Extracellular substance of bone tissue consisting of COLLAGEN fibers, ground substance, and inorganic crystalline minerals and salts.
The second longest bone of the skeleton. It is located on the medial side of the lower leg, articulating with the FIBULA laterally, the TALUS distally, and the FEMUR proximally.
An aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the PSEUDOMONAS species. It is a 10% component of the antibiotic complex, NEBRAMYCIN, produced by the same species.
The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.
Substances that reduce the growth or reproduction of BACTERIA.
The hardening or polymerization of bonding agents (DENTAL CEMENTS) via chemical reactions, usually involving two components. This type of dental bonding uses a self-cure or dual-cure system.
The spinal or vertebral column.
Inorganic compounds that contain calcium as an integral part of the molecule.
Specific alloys not less than 85% chromium and nickel or cobalt, with traces of either nickel or cobalt, molybdenum, and other substances. They are used in partial dentures, orthopedic implants, etc.
The generic term for salts derived from silica or the silicic acids. They contain silicon, oxygen, and one or more metals, and may contain hydrogen. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th Ed)
Bone-forming cells which secrete an EXTRACELLULAR MATRIX. HYDROXYAPATITE crystals are then deposited into the matrix to form bone.
Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
A cellulose derivative which is a beta-(1,4)-D-glucopyranose polymer. It is used as a bulk laxative and as an emulsifier and thickener in cosmetics and pharmaceuticals and as a stabilizer for reagents.
Holding a DENTAL PROSTHESIS in place by its design, or by the use of additional devices or adhesives.
Magnesium oxide (MgO). An inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
A prosthesis or restoration placed for a limited period, from several days to several months, which is designed to seal the tooth and maintain its position until a permanent restoration (DENTAL RESTORATION, PERMANENT) will replace it. (From Jablonski, Dictionary of Dentistry, 1992)
The description and measurement of the various factors that produce physical stress upon dental restorations, prostheses, or appliances, materials associated with them, or the natural oral structures.
The properties, processes, and behavior of biological systems under the action of mechanical forces.
A computer based method of simulating or analyzing the behavior of structures or components.
Any of the numerous types of clay which contain varying proportions of Al2O3 and SiO2. They are made synthetically by heating aluminum fluoride at 1000-2000 degrees C with silica and water vapor. (From Hawley's Condensed Chemical Dictionary, 11th ed)
A scraping, usually of the interior of a cavity or tract, for removal of new growth or other abnormal tissue, or to obtain material for tissue diagnosis. It is performed with a curet (curette), a spoon-shaped instrument designed for that purpose. (From Stedman, 25th ed & Dorland, 27th ed)
A dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)
A dead body, usually a human body.
Poly-2-methylpropenoic acids. Used in the manufacture of methacrylate resins and plastics in the form of pellets and granules, as absorbent for biological materials and as filters; also as biological membranes and as hydrogens. Synonyms: methylacrylate polymer; poly(methylacrylate); acrylic acid methyl ester polymer.
Surgical reconstruction of a joint to relieve pain or restore motion.
Blocking of a blood vessel by fat deposits in the circulation. It is often seen after fractures of large bones or after administration of CORTICOSTEROIDS.
Breaks in bones.
The reaction product of bisphenol A and glycidyl methacrylate that undergoes polymerization when exposed to ultraviolet light or mixed with a catalyst. It is used as a bond implant material and as the resin component of dental sealants and composite restorative materials.
Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
The process of bone formation. Histogenesis of bone including ossification.
The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.
Polymerized forms of styrene used as a biocompatible material, especially in dentistry. They are thermoplastic and are used as insulators, for injection molding and casting, as sheets, plates, rods, rigid forms and beads.
Synthetic resins, containing an inert filler, that are widely used in dentistry.
The hardening or polymerization of bonding agents (DENTAL CEMENTS) via exposure to light.
The plan and delineation of prostheses in general or a specific prosthesis.
VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.
Replacement for a knee joint.
A potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor cells into OSTEOBLASTS.
Procedures used to treat and correct deformities, diseases, and injuries to the MUSCULOSKELETAL SYSTEM, its articulations, and associated structures.
The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS.
A prosthetic restoration that reproduces the entire surface anatomy of the visible natural crown of a tooth. It may be partial (covering three or more surfaces of a tooth) or complete (covering all surfaces). It is made of gold or other metal, porcelain, or resin.
Partial or total replacement of a joint.
The hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root, which is harder and denser than bone but softer than enamel, and is thus readily abraded when left unprotected. (From Jablonski, Dictionary of Dentistry, 1992)
Acrylic acids or acrylates which are substituted in the C-2 position with a methyl group.
Inorganic compounds that contain aluminum as an integral part of the molecule.
A group of twelve VERTEBRAE connected to the ribs that support the upper trunk region.
Elements of limited time intervals, contributing to particular results or situations.
A subfield of acoustics dealing in the radio frequency range higher than acoustic SOUND waves (approximately above 20 kilohertz). Ultrasonic radiation is used therapeutically (DIATHERMY and ULTRASONIC THERAPY) to generate HEAT and to selectively destroy tissues. It is also used in diagnostics, for example, ULTRASONOGRAPHY; ECHOENCEPHALOGRAPHY; and ECHOCARDIOGRAPHY, to visually display echoes received from irradiated tissues.
A type of porcelain used in dental restorations, either jacket crowns or inlays, artificial teeth, or metal-ceramic crowns. It is essentially a mixture of particles of feldspar and quartz, the feldspar melting first and providing a glass matrix for the quartz. Dental porcelain is produced by mixing ceramic powder (a mixture of quartz, kaolin, pigments, opacifiers, a suitable flux, and other substances) with distilled water. (From Jablonski's Dictionary of Dentistry, 1992)
Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull).
Cements that act through infiltration and polymerization within the dentinal matrix and are used for dental restoration. They can be adhesive resins themselves, adhesion-promoting monomers, or polymerization initiators that act in concert with other agents to form a dentin-bonding system.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed)
Materials placed inside a root canal for the purpose of obturating or sealing it. The materials may be gutta-percha, silver cones, paste mixtures, or other substances. (Dorland, 28th ed, p631 & Boucher's Clinical Dental Terminology, 4th ed, p187)
Polymers of high molecular weight which at some stage are capable of being molded and then harden to form useful components.
Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.
The internal resistance of a material to moving some parts of it parallel to a fixed plane, in contrast to stretching (TENSILE STRENGTH) or compression (COMPRESSIVE STRENGTH). Ionic crystals are brittle because, when subjected to shear, ions of the same charge are brought next to each other, which causes repulsion.
A mild astringent and topical protectant with some antiseptic action. It is also used in bandages, pastes, ointments, dental cements, and as a sunblock.
Light sources used to activate polymerization of light-cured DENTAL CEMENTS and DENTAL RESINS. Degree of cure and bond strength depends on exposure time, wavelength, and intensity of the curing light.
One of a pair of irregularly shaped quadrilateral bones situated between the FRONTAL BONE and OCCIPITAL BONE, which together form the sides of the CRANIUM.
An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.
A test to determine the relative hardness of a metal, mineral, or other material according to one of several scales, such as Brinell, Mohs, Rockwell, Vickers, or Shore. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Composite materials composed of an ion-leachable glass embedded in a polymeric matrix. They differ from GLASS IONOMER CEMENTS in that partially silanized glass particles are used to provide a direct bond to the resin matrix and the matrix is primarily formed by a light-activated, radical polymerization reaction.
Use of a metal casting, usually with a post in the pulp or root canal, designed to support and retain an artificial crown.
X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.
Restorations of metal, porcelain, or plastic made to fit a cavity preparation, then cemented into the tooth. Onlays are restorations which fit into cavity preparations and overlay the occlusal surface of a tooth or teeth. Onlays are retained by frictional or mechanical factors.
Relating to the size of solids.
Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.
An inner coating, as of varnish or other protective substance, to cover the dental cavity wall. It is usually a resinous film-forming agent dissolved in a volatile solvent, or a suspension of calcium hydroxide in a solution of a synthetic resin. The lining seals the dentinal tubules and protects the pulp before a restoration is inserted. (Jablonski, Illustrated Dictionary of Dentistry, 1982)
Procedures that avoid use of open, invasive surgery in favor of closed or local surgery. These generally involve use of laparoscopic devices and remote-control manipulation of instruments with indirect observation of the surgical field through an endoscope or similar device.
Use of radiolabeled antibodies for diagnostic imaging of neoplasms. Antitumor antibodies are labeled with diverse radionuclides including iodine-131, iodine-123, indium-111, or technetium-99m and injected into the patient. Images are obtained by a scintillation camera.
A white powder prepared from lime that has many medical and industrial uses. It is in many dental formulations, especially for root canal filling.
The seepage of fluids, debris, and micro-organisms between the walls of a prepared dental cavity and the restoration.
Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
A restoration designed to remain in service for not less than 20 to 30 years, usually made of gold casting, cohesive gold, or amalgam. (Jablonski, Dictionary of Dentistry, 1992)
Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.
A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.
A group of phosphate minerals that includes ten mineral species and has the general formula X5(YO4)3Z, where X is usually calcium or lead, Y is phosphorus or arsenic, and Z is chlorine, fluorine, or OH-. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Materials used in the production of dental bases, restorations, impressions, prostheses, etc.
Benign unilocular lytic areas in the proximal end of a long bone with well defined and narrow endosteal margins. The cysts contain fluid and the cyst walls may contain some giant cells. Bone cysts usually occur in males between the ages 3-15 years.

Cement migration after THR. A comparison of charnley elite and exeter femoral stems using RSA. (1/1009)

Studies using roentgen stereophotogrammetric analysis (RSA) have shown that the femoral components of cemented total hip replacements (THR) migrate distally relative to the bone, but it is not clear whether this occurs at the cement-implant or the cement-bone interface or within the cement mantle. Our aim was to determine where this migration occurred, since this has important implications for the way in which implants function and fail. Using RSA we compared for two years the migration of the tip of the stem with that of the cement restrictor for two different designs of THR, the Exeter and Charnley Elite. We have assumed that if the cement restrictor migrates, then at least part of the cement mantle also migrates. Our results have shown that the Exeter migrates distally three times faster than the Charnley Elite and at different interfaces. With the Exeter migration was at the cement-implant interface whereas with the Charnley Elite there was migration at both the cement-bone and the cement-implant interfaces.  (+info)

Induction of macrophage C-C chemokine expression by titanium alloy and bone cement particles. (2/1009)

Particulate wear debris is associated with periprosthetic inflammation and loosening in total joint arthroplasty. We tested the effects of titanium alloy (Ti-alloy) and PMMA particles on monocyte/macrophage expression of the C-C chemokines, monocyte chemoattractant protein-1 (MCP-1), monocyte inflammatory protein-1 alpha (MIP-1alpha), and regulated upon activation normal T expressed and secreted protein (RANTES). Periprosthetic granulomatous tissue was analysed for expression of macrophage chemokines by immunohistochemistry. Chemokine expression in human monocytes/macrophages exposed to Ti-alloy and PMMA particles in vitro was determined by RT-PCR, ELISA and monocyte migration. We observed MCP-1 and MIP-1alpha expression in all tissue samples from failed arthroplasties. Ti-alloy and PMMA particles increased expression of MCP-1 and MIP-1alpha in macrophages in vitro in a dose- and time-dependent manner whereas RANTES was not detected. mRNA signal levels for MCP-1 and MIP-1alpha were also observed in cells after exposure to particles. Monocyte migration was stimulated by culture medium collected from macrophages exposed to Ti-alloy and PMMA particles. Antibodies to MCP-1 and MIP-1alpha inhibited chemotactic activity of the culture medium samples. Release of C-C chemokines by macrophages in response to wear particles may contribute to chronic inflammation at the bone-implant interface in total joint arthroplasty.  (+info)

The inadequacy of standard radiographs in detecting flaws in the cement mantle. (3/1009)

Radiological assessment of the cement mantle is used routinely to determine the outcome of total hip replacement. We performed a simulated replacement arthroplasty on cadaver femora and took standard postoperative radiographs. The femora were then sectioned into 7 mm slices starting at the calcar, and high-resolution faxitron radiographs were taken of these sections. Analysis of the faxitron images showed that defects in the cement mantle were observed up to 100 times more frequently than on the standard films. We therefore encourage the search for a better technique in assessing the cement mantle.  (+info)

Total knee replacement: should it be cemented or hybrid? (4/1009)

OBJECTIVE: To compare the complication rates associated with total knee arthroplasty against the types of fixation (hybrid or cemented), using a single total knee design (the anatomic modular knee [AMK] prosthesis). DESIGN: A prospective, nonrandomized, controlled trial. SETTING: University Hospital in London, Ont., a tertiary care teaching centre. PATIENTS: Two groups made up of 484 knees in 395 patients (89 bilateral). INTERVENTIONS: In 260 knees a hybrid configuration (cemented tibia and noncemented femur) was used (group 1). In 224 knees the femoral and tibial components were cemented (group 2). All patellae were cemented in both groups. MAIN OUTCOME MEASURES: Clinical results were assessed by The Knee Society Clinical Rating Scores at 3 months, 6 months and yearly intervals. Radiographic results were determined by 3-foot standing radiographs and at each follow-up visit standing knee radiographs, lateral and skyline views. Radiographs were analysed for alignment, presence or absence of radiolucent lines or changes in the position of the implant. All reoperations and nonoperative complications were recorded. RESULTS: At an average follow-up of 4.8 years, 8 knees (1.6%) required reoperation. An analysis of the complications leading to reoperation demonstrated no difference between the 2 groups. CONCLUSIONS: There was no difference in outcome whether the femoral component was cemented or not. Medium-term results of the AMK are excellent with a very low reoperation rate.  (+info)

Massive pelvic and femoral pseudotumoral osteolysis secondary to an uncemented total hip arthroplasty. (5/1009)

A 51 year-old man developed an extensive osteolytic response to wear debris in an uncemented porous-coated total hip arthroplasty, with metal/polyethylene interface, which had been implanted eighteen years previously. This reaction, which involved the upper femur and the ilium, produced a mass which compressed the pelvic viscera.  (+info)

Pulmonary embolism caused by acrylic cement: a rare complication of percutaneous vertebroplasty. (6/1009)

A pulmonary embolus of acrylic cement was present in a 41-year-old woman with Langerhans' cell vertebral histiocytosis (LCH) after percutaneous vertebroplasty. Chest radiograph and CT confirmed pulmonary infarction and the presence of cement in the pulmonary arteries. She was treated with anticoagulants, and responded favorably. This rare complication occurred because perivertebral venous migration was not recognized during vertebroplasty. Adequate preparation of cement and biplane fluoroscopy are recommended for vertebroplasty.  (+info)

More failures of uncemented acetabular screw-rings than of cemented polyethylene cups in total hip arthroplasties. (7/1009)

The results of 498 total hip arthroplasties were prospectively studied. In 329 patients a cemented acetabular polyethylene cup was inserted. In 169 patients a threaded socket without cement was introduced. Follow-up ranged from 6 to 8 years and follow-up rate was over 90%. Of the 169 threaded sockets 8 required revision (4.7%), and 3 acetabular components were seen to be loose on X-ray. Of the cemented cups, only 2 (0.6%) required revision and none were considered loose on X-ray.  (+info)

Mid-term migration of a cemented total hip replacement assessed by radiostereometric analysis. (8/1009)

We have previously reported the short-term migration of cemented Hinek femoral components using radiostereometric analysis (RSA). We now report the mid-term migration. During the first 2 years after implantation the prosthesis subsided into varus and rotated internally. Between years 3 and 8 the prosthesis continued to rotate internally with the head moving posteriorly (0.07 mm/year, P=0.004). It also continued to fall into varus with the tip moving laterally (0.07 mm/year, P=0.04). The head (0.06 mm/year, P<0.0001), shoulder (0.04 mm/year, P=0.0001) and tip (0.04 mm/year, P=0.001) continued to migrate distally. There were two cases of failure due to aseptic loosening during the follow-up period. During the second year both of these had posterior head migration, which was abnormally rapid (>2 SD from the mean). We have demonstrated that a cemented implant has slow but significant levels of migration and rotation for at least 8 years after implantation. Our study confirms that implants with abnormally rapid posterior head migration during the second year are likely to fail.  (+info)

BACKGROUND: Although shoulder arthroplasty is an accepted treatment for osteoarthritis, loosening of the glenoid component, which mainly occurs at the bone-cement interface, remains a major concern. Presently, the mechanical effect of the cement mantel thickness on the bone-cement interface is still unclear. METHODS: Finite element analysis of a prosthetic scapula was used to evaluate the effect of cement thickness on stresses and micromotions at the bone-cement interface. The glenoid component was all-polyethylene, keeled and flat back. Cement mantel thickness was gradually increased from 0.5 to 2.0 mm. Two glenohumeral contact forces were applied: concentric and eccentric. Two extreme cases were considered for the bone-cement interface: bonded and debonded. FINDINGS: Within cement, stress increased as cement thickness decreased, reaching the fatigue limit below 1.0 mm. Bone stress was below its ultimate strength and was minimum between 1.0 and 1.5mm. Interface stress was close to the interface
This study aimed to compare the effect of antibiotic-loaded bone cement (ALBC) versus plain bone cement (PBC) on revision rates for periprosthetic joint infection (PJI) and all-cause revisions following primary elective total hip arthroplasty (THA) and total knee arthroplasty (TKA). MEDLINE, Embase, Web of Science, and Cochrane databases were systematically searched for studies comparing ALBC versus PBC, reporting on revision rates for PJI or all-cause revision following primary elective THA or TKA. A random-effects meta-analysis was performed. The study was registered in the International Prospective Register of Systematic Reviews (PROSPERO ID CRD42018107691). Nine studies and one registry report were identified, enabling the inclusion of 371,977 THA and 671,246 TKA. Pooled analysis for THA demonstrated ALBC was protective against revision for PJI compared with PBC (relative risk (RR) 0.66, 95% confidence interval (CI) 0.56 to 0.77; p < 0.001), however, no differences were seen for all-cause ...
A bone cement mixer having a cartridge filled with bone cement powder and a monomer well for receiving monomer liquid to be flowed into the bone cement powder. The monomer liquid flows by gravity in a stream near the outer periphery of the bone cement powder. The stream penetrates the bone cement powder and forms a partial cylinder of monomer-rich powder essentially uniformly along the height of the bone cement powder. The powder and liquid are then mechanically mixed to form bone cement.
Bone cement has been successfully used to anchor artificial joints. The bone cement delivery system is a series of medical equipment that uses bone cement for treatment. Scope of the Report: Bone cement has been successfully used to anchor artificial joints. The bone cement delivery system is a series of medical equipment that uses bone cement for treatment. Bone cement delivery systems have become popular in various types of orthopedic surgery/surgery. There are many benefits to using this device,
Bone Cement Market 2018 Global Analysis, Growth, Trends and Opportunities Research Report Forecasting to 2023. PUNE, MAHARASHTRA, INDIA, February 13, 2018 / - Summary. adds Bone Cement Market 2018 Global Analysis, Growth, Trends and Opportunities Research Report Forecasting to 2023 reports to its database.. This report provides in depth study of Bone Cement Market using SWOT analysis i.e. Strength, Weakness, Opportunities and Threat to the organization. The Bone Cement Market report also provides an in-depth survey of key players in the market which is based on the various objectives of an organization such as profiling, the product outline, the quantity of production, required raw material, and the financial health of the organization.. Bone cement is used for fixation of prosthesis to living bone in orthopaedic musculoskeletal surgical procedures. Commonly referred to as PMMA (polymethylmethacrylate)In this report, 1 pcs bone cement refers to2 main ...
To prevent complication caused by leakage of bone cement injected into the vertebral body, organism damage caused by the leakage of the monomer or a non-cured component from bone cement and decrease of strength caused by insufficient curing of bone cement, in the percutaneous kyphoplasty, a leakage prevention bag for injecting and filling a bone cement is used, wherein the bad is made of a bioabsorbable material having a molecular weight of 5,000 to 500,000 and has a bag having the thickness of 10 to 800 μm, an injection tube is attached to an injection port for injecting the bone cement of the bag, the bag is inserted into a cavity formed in the vertebra body, and the bone cement is injected and filled into the bag through the tube.
Headline: Bitcoin & Blockchain Searches Exceed Trump! Blockchain Stocks Are Next!. United States Bone Cement Gun Market Production, Supply, Sales, and Demand Research Report is a systematically conducted exhaustive study of the United States Bone Cement Gun market. The aim of the United States Bone Cement Gun Industry report is to assist novice as well as seeded players in gaining astute business intelligence and make apt decisions based on it.. Detailed TOC and Charts & Tables of United States Bone Cement Gun Market Research Report available at- The analysis in the United States Bone Cement Gun Market report is of a two-fold perspective, production and sales. This commercial study encompasses detailed investigation of production, supply, sales, demand, price, cost, income and revenue on United States Bone Cement Gun Industry in Major Regions.. The report analyses the entire production and supply chain of the industry and provides information as per ...
The fracture or failure behaviours of four commercial acrylic-based bone cements have been examined in tensile, bending and compression modes, and their mechanical properties are reviewed. It was found that Palacos R-40 bone cement had high radiopaque agent concentration, with high surface hardness. It exhibited a much lower bending strength and bending modulus compared with the other three bone cements (CMW1, CMW2000 and Simplex P). The textures of tensile fracture surfaces produced were similar for the four bone cements studied. The fracture surface was fragmented by crevices, which developed through the matrix and around large undissolved polymethylmethacrylate (PMMA) beads. Three bands with different features existed on the bending fracture surfaces, with an abrupt transition between them. It appears that the agglomerates of zirconium dioxide particles are implicated in Palacos R-40 bone cement fracture surface. The examination of compressive failed specimens revealed that a yielded crack ...
0003]Polymethylmethacrylate bone cements can be mixed in suitable mixing beakers with spatulas by mixing the cement powder with the monomer liquid. This procedure is disadvantageous in that inclusions of air may be present in the cement dough thus formed and may later cause destabilization of the bone cement. For this reason, it is preferable to mix bone cement powder with the monomer liquid in vacuum mixing systems, since mixing in a vacuum removes inclusions of air from the cement dough all but completely and attains optimal cement quality (Breusch, S. J. et al., Der Stand der Zementiertechnik in Deutschland [The State of Cementing Technology in Germany], Z. Orthop., 137: 101-07 (1999)). Bone cements mixed in a vacuum have substantially lower porosity and thus show improved mechanical properties. A large number of vacuum cementing systems have been disclosed of which the following shall be named for exemplary purposes: U.S. Pat. Nos. 6,033,105; 5,624,184; 4,671,263; 4,973,168; 5,100,241; ...
A bone cement mixing apparatus for mixing a powder bone cement component with a liquid bone cement component includes a bowl and a lid removably secured to the bowl. The lid has a sealable liquid delivery port defined therein which is adapted to sealingly receive an outlet coupling of a liquid delivery device. The bone cement mixing apparatus also includes a crank rotatably attached to the lid and a blade positioned in the bowl. The blade is secured to the crank such that rotation of the crank causes rotation of the blade. A method for mixing bone cement is also disclosed.
Global Bone Cement & Glue Market report delineates the thorough and collective examination of Bone Cement & Glue industry during the past, present and conjecture period. All the business verticals like aggressive market situation, regional Bone Cement & Glue nearness, and improvement openings are clarified. Top players (Stryker, Zimmer Biomet, Depuy Synthes (A Part Of Johnson & Johnson), Smith & Nephew, Arthrex, Djo Global, Exactech, Teknimed, Heraeus Medical, Cryolife, Cardinal Health, Trimph) of Bone Cement & Glue industry, their business strategies, and growth opportunities are covered in this report. A report is incomplete without having the knowledge of the key players or competitors within the market. Many basic aspects build the market that drives the expansion of associate degree trade or an organization.. Get an exclusive sample of research report: Report Sample. The report analyses the Bone Cement & Glue market based on its engaging quality and venture achievability. Likewise, it ...
We studied fluid flow at the stem-cement interface of bonded and debonded, polished and rough model femoral components. In a first series of experiments, fluid flow along the interface between bone cement and well-fixed model femoral components, differing in surface finish, and in shape, was measured. Fluid migration along the bone-cement interface of rough stems (Ra 3 microm) was greater than that on polished stems (p | 0.001). This was true of cylindrical and conical tapered stems. On stems with the same surface finish, shape did not influence fluid migration. In a second series of experiments, fluid flow along the stem-cement interface of 5 highly polished and 10 rough-finished (5 of Ra approximately 1.5 microm and 5 of Ra approximately 3 microm), debonded, tapered circular stems was measured. None of the rough stems could prevent fluid flow along the stem-cement interface. Polished tapered stems sealed the interface and, after 48 hrs of continuous pressure, no fluid flow was observed. This
icotec ag partners with G-21 to provide combined bone cement and delivery solution for pedicle screw augmentation procedures. (Credit: PRNewsfoto/icotec ag). icotec ag, a leading medical device manufacturer of Carbon/PEEK implants, strategically corporates with G-21 to distribute their bone cements in conjunction with icotecs VADER® Pedicle Screw System in the United States.. The VADER® Pedicle System is intended to restore the integrity of the spinal column even in the absence of fusion in patients with advanced stage tumors involving the thoracic or lumbar spine in whom life expectance, prior to oncological treatment, is of insufficient duration to permit achievement of fusion.. The VADER® screws fenestration allows for bone cement augmentation following icotecs state-of-the-art standard open, minimally invasive, or percutaneous surgical procedure to increase stability in patients with compromised bone quality caused by spinal tumors.. The G-21 bone cements are a perfect complement to ...
Market Trends. Several techniques have been implemented in recent years to prevent bone infections, including stringent and effective antiseptic operative processes and systemic antibiotic prophylaxis. The use of antibiotic-loaded bone cement is becoming increasingly common among these procedures. Demand for the product is also being driven by the rising prevalence of osteoporosis and hip and knee replacement surgeries, particularly among the aging population.. Moreover, Other factors driving market growth include continued growth in the orthobiological industry, progressing healthcare industry and rising public awareness. Rapid technological advancements and increased research and development activities are expected to boost the global antibiotic bone cement industrys growth during the forecast period.. Read Full Report Online: Key Market Players. The major players in the market are Smith & Nephew, Inc., Stryker ...
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Two-stage exchange with antibiotic-loaded bone cement spacers remains the gold standard for chronic periprosthetic joint infection (PJI). Rifampicin is highly efficient on stationary-phase staphylococci in biofilm; however, its addition to PMMA to manufacture spacers prevents polymerization and reduces mechanical properties. Isolation of rifampicin during polymerization by microencapsulation could allow manufacturing rifampicin-loaded bone cement maintaining elution and mechanical properties. Microcapsules of rifampicin with alginate, polyhydroxybutyratehydroxyvalerate (PHBV), ethylcellulose and stearic acid (SA) were synthesized. Alginate and PHBV microcapsules were added to bone cement and elution, compression, bending, hardness, setting time and microbiological tests were performed. Repeated measures ANOVA and Bonferroni post-hoc test were performed, considering a p,0.05 as statistical significance. Bone cement specimens containing alginate microcapsules eluted more rifampicin than PHBV ...
Bone cement creep behavior was studied using commercial available clinical bone cement. Creep deformation was measured using a micrometer with a resolution of 1 μm. It was demonstrated that the restraint has a very strong effect on the creep of bone cement, half-restrained specimens creep more than that of fully restrained specimens. The creep of the investigated bone cement increased with the dynamic loading cycles, and two creep stages, a high initial creep rate followed by a steady creep stage, can be identified. The relationship between the creep deformation and the loading cycles was expressed by a single logarithmic model.. ...
The Global market size of Bone cement mixers is $XX million in 2018 with XX CAGR from 2014 to 2018, and it is expected to reach $XX million by the end of 2024 with a CAGR of XX% from 2019 to 2024.. Global Bone cement mixers Market Report 2019 - Market Size, Share, Price, Trend and Forecast is a professional and in-depth study on the current state of the global Bone cement mixers industry. The key insights of the report:. Download for a sample copy of this report @ 1.The report provides key statistics on the market status of the Bone cement mixers manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry.. 2.The report provides a basic overview of the industry including its definition, applications and manufacturing technology.. 3.The report presents the company profile, product specifications, capacity, production value, and 2013-2018 market shares ...
The efficacy of antibiotic-loaded acrylic bone cements (ALBC) for prophylaxis of deep surgical site infections (deep SSIs) after primary cemented joint replacement surgery remains controversial. Therefore, the purpose of this study was to examine the issue, with respect to three types of arthroplasty, namely, total knee arthroplasty (TKA), total hip arthroplasty (THA), and bipolar hip arthroplasty (BHA).
The mechanical effects of varying the depth of cement penetration in the cement-bone interface were investigated using finite element analysis (FEA) and validated using companion experimental data. Two FEA models of the cement-bone interface were created from micro-computed tomography data and the penetration of cement into the bone was varied over six levels each. The FEA models, consisting of the interdigitated cement-bone constructs with friction between cement and bone, were loaded to failure in tension and in shear. The cement and bone elements had provision for crack formation due to excessive stress. The interfacial strength showed a strong relationship with the average interdigitation (r(2)=0.97 and r(2)=0.93 in tension and shear, respectively). Also, the interface strength was strongly related with the contact area (r(2)=0.98 and r(2)=0.95 in tension and shear, respectively). The FEA results compared favorably to the stiffness-strength relationships determined experimentally. Overall, ...
A novel bone cement composed of sintered zinc-calcium-silicate phosphate and hybrid polyalkenoates has been developed. Synthesis and formulation of glass fillers, monomers and polymers as well as formulation of the cement were described. The effects of sintering, polymer content, glass powder/polymer liquid (P/L) ratio and comonomer on compressive strength (CS) and curing time (CT) were investigated. The effects of P/L ratio and comonomers on shrinkage as well as exotherm were also studied. Results show that the experimental cement was 61% higher in CS, 10% lower in diametral tensile strength, 35% lower in flexural strength, 62% less in exotherm, and 68% less in shrinkage, compared to conventional polymethylmethacrylate cement. With increasing polymer content and P/L ratio in the cement formulation CS of the cement increased but CT decreased. Curing time, shrinkage and exotherm of the cement decreased with increasing P/L ratio. It appears that this novel cement may be a potential candidate for ...
A custom made femoral component is made using the femoral cavity and an internal latex envelope as the mold. After the femoral cavity is worked into a roughly conical shape, an internal latex envelope is inserted into the cavity and filled with bone cement. An endoskeleton is inserted down the femoral cavity into the bone cement. The internal latex mold conforms to the shape of the cavity and an accurate negative of the cavity is created as the bone cement solidifies. The femoral component is pulled from the cavity and the internal latex envelope is peeled off the component. All traces of the internal latex envelope is removed from the femoral cavity and component. The femoral component is then reimplanted.
A prosthetic cement spacer for controlling the thickness of cement applied between a prosthetic insert and a support member, such as an acetabulum, includes a generally cylindrical standoff body portion fabricated from acrylic bone cement and a pointed wire concentric with said standoff body and outwardly extending from one end a sufficient length to anchor into the acetabulum bone surface. The method of use of these prosthetic cement spacers involves preparation of the acetabulum so that there is sufficient clearance space for the prosthetic cement spacers and then to insert the pointed wires into the acetabulum bone surface in an equilateral triangular arrangement thereby providing three points of contact for the prosthetic insert, such as an acetabular cup. By selecting three prosthetic cement spacers all having substantially the same standoff body height, the clearance region between the acetabulum bone surface and the acetabular cup is controlled and provides a uniform cement thickness
The standard cementing technique for total hip and knee arthroplasty (THA, TKA) was modified by interposing osteoconductive porous polycrystalline hydroxyapatite (HA) granules at the cement-bone interface to augment cement-bone bonding. Twenty-one specimens from the acetabulum and two specimens from the femur containing well-fixed bone-cement interface were retrieved five months to twenty-two years after THA and TKA with an interface bioactive bone cement technique. Histological findings were evaluated in terms of the retrieved sites, the interval between index operation and revision, patient age at retrieval and bone pathology. Dense bone ingrowth was observed in all specimens retrieved from the superior wall of the acetabulum. Cancellous bone ingrowth was observed in specimens retrieved from the infero-medial wall of the acetabulum. Connective tissue interposition and osteolysis were observed at the sites where hydroxyapatite granules were absent. Findings of bone ingrowth for the HA ...
2018 Trans Tech Publications, Switzerland. In this research, mechanical properties of bone cement containing micro- and nano-hydroxyapatite (HAp) particles were studied. The bone cement was prepared from mixing between polymethyl methacrylate (PMMA) and methyl methacrylate (MMA). Hydroxyapatite powder was prepared from bovine bone. The bone was heated in hot water at 200oc for the elimination of tissue, after which the bone was dried and calcined at 800oc for 3 hrs. The calcined bone then was crushed into powder and ball-milled for 24 hrs. The micro-HAp particle was then obtained. The micro particles were then further milled employing the Vibro-milling machine for 2 hrs. The micro- and nano- HAp sizes are about 0.5 µm and 140 nm, respectively. The both size powders were treated with γ-methacrylic-propyl-tri-methoxy silane. The acetic acid was added to control the pH of the solution, until it reached 2.9 before they were mixed into the bone cement with equally wt%. The mixture was casted using ...
TY - JOUR. T1 - LOWER RISK OF THROMBOEMBOLIC DISEASE AFTER TOTAL HIP REPLACEMENT WITH NON-CEMENTED THAN WITH CEMENTED PROSTHESES. AU - Francis, C. W.. AU - Marder, V. J.. AU - Evarts, C. M.. PY - 1986/4/5. Y1 - 1986/4/5. N2 - During the course of a prospective, randomised trial comparing dextran 40 with antithrombin III plus heparin as prophylaxis against thrombosis after total hip replacement, an unexpectedly low incidence of postoperative thromboembolic disease was found in patients receiving non-cemented (0 of 23) rather than cemented prostheses (4 of 13, 31%). Despite the small number of patients, the difference was significant and necessitated modification of the protocol. These preliminary findings suggest that the type of hip replacement used was more important than the type of antithrombotic medication in preventing venous thrombosis and pulmonary embolism.. AB - During the course of a prospective, randomised trial comparing dextran 40 with antithrombin III plus heparin as prophylaxis ...
Seda is a supplier of G21 Bone Cement: find out more on this quality orthopedic bone cement, used in Vertebroplasty and other applications. Download data sheet.
Antibiotics 2014-2019Viscosity 2014-2019Vacuum mixing system 2014-2019 Elbow » Primary elbow arthroplasty » Bone cement » Antibiotics 2014-2019 Elbow » Primary elbow arthroplasty » Bone cement » Viscosity 2014-2019 Elbow » Primary elbow arthroplasty » Bone cement » Vacuum mixing system 2014-2019
Two-stage revision arthroplasty is today considered as the gold standard for control of chronic deep prosthetic infection. Although the revision arthroplasty should only be considered when infection is eliminated, the diagnosis of residual infection prior to the revision remains a challenging problem. We evaluated triple-phase bone scintigraphy as a useful diagnostic test for the detection of residual infection around the antibiotic-impregnated cement spacer in patients waiting for the second-stage revision hip or knee arthroplasty. Increased uptake of radioisotope in all three phases was considered positive for infection. The final diagnosis was based on histopathological results in addition to microbiologic examinations of surgical specimens. Histopathological examination showed positive in 17 and negative in 13 out of 30 examinations. Among 17 samples positive for histopathology, there were only 4 samples positive for bacterial culture. All samples negative for histopathology showed negative for
Poly (methyl methacrylate) (PMMA) bone cement is widely used in vertebral body augmentation procedures such as vertebroplasty and balloon kyphoplasty. Filling high modulus PMMA increases the modulus of filled verterbra, increasing the risk of fracture in the adjacent vertebra. On the other hand, in porous PMMA bone cements, wear particle generation and deterioration of mechanical performance are the major drawbacks. This study adopts a new approach by utilizing linoleic acid coated strontium substituted hydroxyapatite nanoparticle (Sr-5 HA) and linoleic acid as plasticizer reducing bone cements modulus with minimal impact on its strength. We determined the compressive strength (UCS) and modulus (Ec), hydrophobicity, injectability, in vitro bioactivity and biocompatibility of this bone cement at different filler and linoleic acid loading. At 20 wt % Sr5-HA incorporation, UCS and Ec were reduced from 63 ± 2 MPa, 2142 ± 129 MPa to 58 ± 2 MPa, 1785 ± 64 MPa, respectively. UCS and Ec were ...
Current commercial polymethylmethacrylate based antibiotics-loaded bone cements exhibit low drug release antibiotics embedded inside polymerized bone cement
TY - JOUR. T1 - The effect of vacuum mixing and pre-heating the femoral component on the mechanical properties of the cement mantle. AU - Baleani, M.. AU - Bialoblocka-Juszczyk, E.. AU - Engels, G. E.. AU - Viceconti, M.. PY - 2010/3. Y1 - 2010/3. N2 - We investigated the effect of pre-heating a femoral component on the porosity and strength of bone cement, with or without vacuum mixing used for total hip replacement. Cement mantles were moulded in a manner simulating clinical practice for cemented hip replacement. During polymerisation, the temperature was monitored. Specimens of cement extracted from the mantles underwent bending or fatigue tests, and were examined for porosity. Pre-heating the stem alone significantly increased the mean temperature values measured within the mantle (+14.2°C) (p ,0.001) and reduced the mean curing time (-1.5 min) (p ,0.001). The addition of vacuum mixing modulated the mean rise in the temperature of polymerisation to 11°C and reduced the mean duration of the ...
TY - CONF. T1 - Characterisation of mechanical properties of acrylic bone cement as a function of aging conditions and mixing environment. AU - Makem, Jonathan. PY - 2005/1. Y1 - 2005/1. M3 - Paper. SP - 326. EP - 335. ER - ...
F2118-14 Standard Test Method for Constant Amplitude of Force Controlled Fatigue Testing of Acrylic Bone Cement Materials constant-amplitude uniaxial tension-compression fatigue~
The cement-bone interface plays an important role in load transfer between cemented implant systems and adjacent bone, but little is known about the micromechanical behavior of this interface following in vivo service. Small samples of postmortem-retrieved cement-bone specimens from cemented total hip replacements were prepared and mechanically loaded to determine the response to tensile and compressive loading. The morphology of the cement-bone interface was quantified using a CT-based stereology approach. Laboratoryprepared specimens were used to represent immediate postoperative conditions for comparison. The stiffness and strength of the cement - bone interface from postmortem retrievals was much lower than that measured from laboratory-prepared specimens. The cement-bone interfaces from postmortem retrievals were very compliant (under tension and compression) and had a very low tensile strength (0.21±0.32 MPa). A linear regression model, including interface contact fraction and ...
PURPOSE The usual treatment in cervical nerve root compression syndrome is the ventral fusion with bone cement. We examined the influence of this interponate on the postoperative changes of the cervical spine. MATERIALS AND METHODS 33 patients were followed-up postoperatively over 6 months, who were treated with 39 ventral fusions because of cervical myelopathy. The lateral view of the cervical spine was used to measure the size of the bone cement interponate, the height of the intervertebral body space and the angle of both vertebral bodies. RESULTS There was no change on the size of the interponate. Postoperatively there was a slight enlargement of the intervertebral body space. During further follow-up examinations there was a decrease to the preoperative size because of the destruction of the endplates. Similar to this observation, there was a change of the angle in the operated segment. First there was a decrease of the angle, later an increase. 6 months postoperatively the preoperatively
Robust fixation of implants is very important as in younger patients these joints are required to last 20 to 30 years or even more. Charnley used a material called acrylic bone cement to fix the implants to the bone which had previously been used by dental surgeons and this material can still be very effective. The bone cement is made by mixing a fluid component with a powder component and the liquid becomes doughy within a few minutes, becomes like putty within about four of five minutes and most cements set around the ten minute mark. The exact setting characteristics of the cement do differ somewhat depending on the different types of materials used in the bone cement. So some bone cements can set quite quickly in five minutes and others can set over a longer period over 15 minutes. Once set the cement is very strong under compression and forms a very good bond between the prosthesis whether it be the femoral component or acetabular component or indeed the femoral component of a knee ...
In a device for injecting bone cement, the discharge direction of the bone cement after insertion of the cannula should be controllable in a certain region. This is made possible through a radial exit aperture ( 5 ) which is provided on the front end of the cannula ( 3 ). Since the cannula is inserted with the aid of a guide wire ( 1 ), it has an orifice ( 4 ) on its front end, which orifice must be closed off by means of a ball ( 15 ) prior to the injection. A plunger serves to insert the ball ( 15 ). So that the situation of the radial aperture ( 5 ) is known at all times, even with inserted cannula, the handle ( 17 ) of the cannula has an asymmetrical shape.
SEATTLE (AP) -- The physician who used a non-FDA-approved bone cement during a womans spinal surgery and the company that ran an illegal test market to promote the dangerous product should be held accountable for her death, a lawyer for the womans daughter told a jury Monday.. Reba Golden was vibrant and healthy when she agreed to let Dr. Jens Chapman operate on her back in 2007, but the surgeon never told Golden or her family that he planned to use a bone cement associated with blood clotting and patient deaths, said attorney Rick Friedman, who represents Cynthia Wilson in a lawsuit against the surgeon, the University of Washington and Synthes Inc.. Read More. ...
GlobalDatas new report, Asia-Pacific Orthopedic Bone Cement and Casting Materials Market Outlook to 2020, provides key market data on the Asia-Pacific Orthopedic Bone Cement and Casting Materials
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Orthopedic Bone Cement Market Trends, Analysis, Industry Overview and Business Research Reports. Orthopedic Bone Cement Market Syndicate Report, Share, Size and Forecast Reports - UK and US
The invention relates to surgical bone cement compositions and more particularly to bone cement compositions having aneasthetic properties, and to methods for producing analgesia.
Bone cement PubMed Central PMC. Dec 15 2013 · 2 Historical perspective Themistokles Gluck 1870 had fixed a total knee prosthesis made of ivory using cement made of plaster and colophony 3 Otto Rohm and Kulzer were early pioneers who worked extensively on the physical properties and uses of bone cement The era of modern PMMA bone cements comes from the patent by Degussa and Kulzer 1943 who had described the Read More + ...
A bone cement having a dry component including a large constituent and a small constituent. The small constituent fills a substantial volume of the interstitial spaces between the particles of the large constituent. Therefore, only a second or minor interstitial space is left remaining between the individual particles of the small constituent and the particles of the small constituent and the particles of the large constituent. Therefore, a reduced amount of a polymerizable component need be added to the dry component to form a bone cement. Such a bone cement formulation decreases the exothermic temperature of the bone cement and decreases the possibility of tissue necrosis in the implantation area.
Distance traveled by the cement restrictor increased, which was statistically signifi-cant p .0006. this also correlated with the cement grade p .0007. cement type low viscosity cement orthoset 3 radioopaque bone cement wright medical technology was used in 37 pro-cedures and high viscosity cement zimmer bone cement dough type feature .
The demand for hip and knee joint operations is increasing rapidly. Today, doctors implant almost 200,000 artificial hips and 120,000 knee joint prostheses (endoprosthetics) every year in Germany alone. Implanting artificial joints has become routine but still presents challenges, since the success of the operation depends on the secure and long-term anchoring of the prostheses in bone. Heraeus Medical has been developing specialized bone cements and the related mixing systems for many years. Now, with an innovative ready-to-use cementing system, Dr. Sebastian Vogt (Heraeus Medical) has simplified mixing and handling bone cement for doctors and surgical staff. Dr. Vogt and his team have developed a completely new, paste-like bone cement. Previously, bone cement came powdered and had to be combined with a liquid in a vacuum system, then mixed to form a homogeneous paste. Now the innovative paste-like bone cement can be applied directly to the implant site in a patients hip or knee with a ...
TY - JOUR. T1 - Fatigue crack propagation in polymethylmethacrylate bone cements. AU - Wright, Timothy M.. AU - Robinson, Raymond P.. PY - 1982/9/1. Y1 - 1982/9/1. N2 - The fatigue crack propagation behaviour of a conventional polymethylmethacrylate (PMMA) bone cement was examined and compared with those of a low-viscosity PMMA cement and a carbon-fibre reinforced PMMA cement. The low-viscosity PMMA cement, developed for use in cement pressurization systems, did not differ significantly from conventional PMMA cement in its crack propagation behaviour. The carbon-fibre reinforced PMMA cement exhibited crack propagation rates which were approximately an order of magnitude less than those of conventional PMMA at the same range of stress intensity factor. Fractography of the test specimens revealed separation around prepolymerized PMMA beads and void formation around barium sulphate particles. Examination of carbon reinforced PMMA specimens showed poor mechanical bonding between the carbon fibres ...
The population in developed countries is ageing and the number of people experiencing joint-related conditions, such as osteoarthritis, is expected to increase. Joint replacements are currently the most effective treatment for severe joint conditions and although many of these procedures are successful, infection developing after the procedure is still an issue, requiring complex and expensive revisions. Whilst incorporating a powdered antibiotic within the bone cement can reduce infection rates, the powder frequently agglomerates, resulting in poor antibiotic release characteristics and compromised mechanical performance of the cement. To overcome these issues, a novel delivery system consisting of antibiotic-loaded nano-sized liposomes was developed for inclusion into polymethyl methacrylate (PMMA) bone cement. This system was tested in a commercial cement (Palacos R) and consistently delivered a higher percentage (22%) of the incorporated antibiotic when compared to the powdered antibiotic ...
Although poly(methylmethacrylate) (PMMA) cements are widely used in orthopaedics, they have numerous drawbacks. This study aimed to improve their bioactivity and osseointegration by incorporating strontium-containing borate bioactive glass (SrBG) as the reinforcement phase and bioactive filler of PMMA cement. The prepared SrBG/PMMA composite cements showed significantly decreased polymerization temperature when compared with PMMA and retained properties of appropriate setting time and high mechanical strength. The bioactivity of SrBG/PMMA composite cements was confirmed in vitro, evidenced by ion release (Ca, P, B and Sr) from SrBG particles. The cellular responses of MC3T3-E1 cells in vitro demonstrated that SrBG incorporation could promote adhesion, migration, proliferation and collagen secretion of cells. Furthermore, our in vivo investigation revealed that SrBG/PMMA composite cements presented better osseointegration than PMMA bone cement. SrBG in the composite cement could stimulate new-bone
The gold standard for bone replacement today, autologous bone, suffers from several disadvantages, such as the increased risk of infection due to the need for two surgeries. Degradable synthetic materials with properties similar to bone, such as calcium phosphate cements, are a promising alternative. Calcium phosphate cements are suited for a limited amount of applications and improving their physical properties could extend their use into areas previously not considered possible. For example, cement with increased strength could be used as load bearing support in selected applications. The focus of this thesis is, therefore, on how the physical properties of acidic calcium phosphate cements (brushite cements) are affected by compositional variations, with the ultimate aim of making it possible to formulate brushite cements with desired properties.. In this thesis a method to measure the porosity of a cement was developed. This method is advantageous over existing methods as it is easy to use, ...
The gold standard for bone replacement today, autologous bone, suffers from several disadvantages, such as the increased risk of infection due to the need for two surgeries. Degradable synthetic materials with properties similar to bone, such as calcium phosphate cements, are a promising alternative. Calcium phosphate cements are suited for a limited amount of applications and improving their physical properties could extend their use into areas previously not considered possible. For example, cement with increased strength could be used as load bearing support in selected applications. The focus of this thesis is, therefore, on how the physical properties of acidic calcium phosphate cements (brushite cements) are affected by compositional variations, with the ultimate aim of making it possible to formulate brushite cements with desired properties.. In this thesis a method to measure the porosity of a cement was developed. This method is advantageous over existing methods as it is easy to use, ...
Has bone cement in a procedure failed requiring revision surgery? Suffered from Bone Cement Implantation Syndrome? Lawyers handling bone cement lawsuits.
Ball Mills Cement Factory For Clinker Mixing , Crusher ... cement factory for clinker mixing , ® Crusher. Heavy Industry(shanghai) is the best cement factory for clinker mixing manufacturers and suppliers ... » Request a quotation. Cement mill,Cement mill price,Raw material mill,China ... The Handling Materials and Application of Cement Mill: Cement mill is widely used for the cement, the silicate product, new type building material, fire-proof ... » Request a quotation. UNITED STATES PORTLAND CEMENT PLANTS UNITED STATES PORTLAND CEMENT PLANTS (Ranked by size, ... RC Cement Company, Inc. - Festus, MO Essroc Cement Corp. - Nazareth, PA Texas Industries - Oro Grande, CA » Request a quotation. Cement production line,Cement making plant,Cement ... The Major Equipment of Cement Production Line: The main equipment of cement production line are vibrating feeder, jaw crusher, impact crusher, cement ball mill, lifer ... » Request a quotation. Chapter 1 - Introduction to Cement Production Chapter 1 - ...
TY - CONF. T1 - Incorporation of chitosan in acrylic bone cement: effect on antibiotic release and bacterial biofilm formation.. AU - Brady, Aaron. AU - Tunney, Michael. AU - Dunne, Nicholas. PY - 2007. Y1 - 2007. KW - biofilm. KW - bone cement. M3 - Poster. T2 - Society for General Microbiology. Y2 - 1 March 2012 through 1 March 2012. ER - ...
Kerrier calcium sulfate beads are fully absorbable unlike PMMA bone cement and have clear advantages over commercial Plaster of Paris (POP). Order online today.
Calcium phosphate cements are used in medicine to fill bone defects or give support to screws and plates in fracture fixation. The cements are formed via mixing a powder with water and the mixture harden through a dissolution-precipitation reaction. Today the cement mixing is performed in the operating room and consists of several complicated steps that need to be performed under sterile conditions. This renders the mixing a risk factor, potentially leading to harm for the patient e.g. unsatisfactory healing or infection. To reduce this risk, premixed cements have been developed using glycerol as mixing liquid. The premixed cement sets when it is exposed to body liquids. Therefore, premixed cement can be delivered to the operating room in prefilled syringes ready for use, thus eliminating the mixing step.. The aim of this thesis is to describe differences between premixed and water-mixed cements and their advantages and drawbacks. The differences will be discussed based on results obtained from ...
Pre-revision radiographs showed the presence of both full and partial RLL. On contact radiographs of 5 mm thick sections of the interface the total percentage of radiolucency ranged from 0 to 90% between patients. There was no consistent pattern for the distribution of radiolucency. Histological assessment demonstrated that under every tibial component there were areas where there was direct contact and interdigitation between bone and cement. The amount of direct bone-cement contact was between 19% and 95% of the tibial tray surface area. The remaining tissue was mainly fibrocartilage but there was also fibrous tissue. The presence of radiolucency was strongly inversely correlated with the percentage of cement-bone contact ...
Bioceramics 19: The Effect of Lif-Maleic Acid Added Calcium Aluminate Bone Cement and Ca-PMMA Composite Bone Cement on Bone Regeneration in Rat Calvarial Defects
Calcium phosphate cements (CPC) are well-established bone replacement materials that have been used in dentistry and orthopedics for more than 25 years. The monitoring of bone cements and the associated healing processes in the human body is difficult and so far has often been achieved using cytotoxic X-ray contrast agent additives. These additives have a negative effect on the mechanical properties and setting time of the bone cement. In this paper, we present a novel approach to prepare contrastive CPC by the incorporation of luminescent Eu3+-doped hydroxyapatite (Eu:HAp) nanoparticles. Eu-doped CPC (Eu:CPC) exhibited enhanced mechanical properties compared to pure CPC. Furthermore, the red photoluminescence of Eu:CPC may allow the observation of CPC-related healing processes without the use of harmful ionizing radiation.
Characterization of the intricate pore structure of calcium phosphate cements is a key step to successfully link the structural properties of these synthetic bone grafts with their most relevant properties, such as in vitro or in vivo behaviour, drug loading and release properties, or degradation over time. This is a challenging task due to the wide range of pore sizes in calcium phosphate cements, compared to most other ceramic biomaterials. This work provides a critical assessment of three different techniques based on different physical phenomena, namely mercury intrusion porosimetry (MIP), Nitrogen sorption, and thermoporometry (TPM) for the detailed characterization of four calcium phosphate cements with different textural properties in terms of total porosity, pore size distribution (PSD), and pore entrance size distribution (PESD). MIP covers a much wider size range than TPM and Nitrogen sorption, offering more comprehensive information at the micrometer level. TPM, and especially ...
A heavy infiltrate of foreign-body macrophages is commonly seen in the fibrous membrane which surrounds an aseptically loose cemented implant. This is in response to particles of polymethylmethacrylate (PMMA) bone cement and other biomaterials. We have previously shown that monocytes and macrophages responding to particles of bone cement are capable of differentiating into osteoclastic cells which resorb bone. To determine whether the radio-opaque additives barium sulphate (BaSO4) and zirconium dioxide (ZrO2) influence this process, particles of PMMA with and without these agents were added to mouse monocytes and cocultured with osteoblast-like cells on bone slices. Osteoclast differentiation, as shown by the presence of the osteoclast-associated enzyme tartrate-resistant acid phosphatase (TRAP) and lacunar bone resorption, was observed in all cocultures. The addition of PMMA alone to these cocultures caused no increase in TRAP expression or bone resorption relative to control cocultures. Adding PMMA
WEDNESDAY, April 7, 2021 (HealthDay News) - Among patients with normal renal function at baseline who are treated with a high-dose antibiotic-loaded bone cement (ALBC) spacer and systemic antibiotic therapy after resection of a periprosthetic joint infection (PJI) following a primary total knee arthroplasty (TKA), 14 percent develop acute kidney injury (AKI), according to a study published online March 29 in The Journal of Bone & Joint Surgery.. Louis Dagneaux, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues examined the incidence, risk factors, and outcomes of AKI in a cohort of 424 patients who had been treated with 455 ALBC spacers after resection of a PJI following a primary TKA from 2000 to 2017. The spacers contained a mean of 8 g of vancomycin and 9 g of an aminoglycoside per construct; 86 spacers also had amphotericin B. All patients also received systemic antibiotics for a mean of six weeks.. The researchers identified 54 AKIs in 52 of the 359 patients (14 percent) ...
This video demonstrates placing gel foam (GF) soaked in adrenaline around incudostapedial joint in all directions. Important structures around joint segregated so as to avoid any over spillage of bone cement on surrounding structures. Bone cement paste dropped over incudostapedial joint. Final cementing of incudostapedial joint. Make sure the cement is not touching any structure other than the joint after final placement.
A double-blind study release on August 5, 2009 in the New England Journal of Medicine showed that vertebroplasty a procedure that involves the injection of medical cement into the spines of patients who have spinal fractures proved only equally effective as simulated vertebroplasty with no spinal cement injection. One group of patients received the actual vertebroplasty procedure, and the control group received a mock procedure including everything but the cement injections into their spines.. The studys leader, Dr. David Kallmes, said that while vertebroplasty has been long accepted and utilized as a treatment option for many years, there has been no data or research to verify its effectiveness. The findings of the study conducted by a team of researchers at the Mayo Clinic in Rochester, MN showed that relief of pain and improvement in dysfunctions related to the pain proceeded similarly in both the group of patients who received the vertebroplasty and the control group who did not. The ...
This study aims to evaluate in vitro the release properties and biological behavior of original compositions of strontium (Sr)-loaded bone mineral cements. Strontium was introduced into vaterite CaCO3-dicalcium phosphate dihydrate cement via two routes: as SrCO3 in the solid phase (SrS cements), and as SrCl2 dissolved in the liquid phase (SrL cements), leading to different cement compositions after setting. Complementary analytical techniques implemented to thoroughly investigate the release/dissolution mechanism of Sr-loaded cements at pH 7.4 and 37°C during 3 weeks revealed a sustained release of Sr and a centripetal dissolution of the more soluble phase (vaterite) limited by a diffusion process. In all cases, the initial burst of the Ca and Sr release (highest for the SrL cements) that occurred over 48 h did not have a significant effect on the expression of bone markers (alkaline phosphatase, osteocalcin), the levels of which remained overexpressed after 15 days of culture with human ...
Fluid Penetration into Antimicrobial Loaded Bone Cement is a Good Indicator for Antimicrobial Release. Background: Antimicrobial loaded bone cement (ALBC)
C~ment® is a product range of bone cements that is used for the fixation of artificial joints. Bone cement fills the space between the prosthesis and the bone. It allows for an immediate and stable fixation of the surgical implant. The C~ment® product range distinguishes itself by its convenient mixing characteristics and excellent mechanical properties.. C~ment is a European Registered Trade Mark property of Biomed of France. C~® is a copyright Logo and Registered Trade Mark of Biomed of France.. C~ment® is available in four types:. - a standard viscosity C~ment® 1 in a 40g pack ...
Megjegyzés: Chemicals/CAS: amikacin, 37517-28-5, 39831-55-5; cefazolin, 25953-19-9, 27164-46-1; clindamycin, 18323-44-9; daptomycin, 103060-53-3; flucloxacillin, 1847-24-1, 5250-39-5; fusidic acid, 6990-06-3; gentamicin, 1392-48-9, 1403-66-3, 1405-41-0; meropenem, 96036-03-2; oxacillin, 1173-88-2, 66-79-5, 7240-38-2; palacos, 9011-14-7, 9011-87-4; tobramycin, 32986-56-4; vancomycin, 1404-90-6, 1404-93-9; Anti-Bacterial Agents; Polymethyl Methacrylate, 9011-14-7 Tradenames: Cemex; Endurance; Palacos, Schering Plough; SmartSet Manufacturers: Schering ...
The RFA and/or vertebroplasty with cement injection were successful in all patients (100%). Except for one patient who had cement leakage, no intraprocedural complications occurred. After RFA, severe refractory pain was greatly relieved in all patients, with pretreatment VAS score of 8.1±1.4 significantly reduced to 5.5±1.1 at 24 h, 2.8±0.6 at one week and 1.4±0.8 at 6 months (P,0.01). The EORTC QLQ-C30 scale at one month demonstrated significant improvement (P,0.05) in the physical (P=0.03) and emotion function (P=0.003), global health status (P=0.002), pain (P=0.001) and insomnia (P=0.002). The analgesics were reduced after the procedure and stopped two months later in all patients, with greatly improved quality of life and no apparent pain. Followed up for 6-12 months, all patients remained alive with no recurrence of pain. ...
In orthopaedics, PMMA bone cement is used to affix implants and to remodel lost bone. It is supplied as a powder with liquid methyl methacrylate (MMA). When mixed these yield a dough-like cement that gradually hardens. Surgeons can judge the curing of the PMMA bone cement by pressing their thumb on it. Although PMMA is biologically compatible, MMA is considered to be an irritant and a possible carcinogen. PMMA has also been linked to cardiopulmonary events in the operating room due to hypotension. [8] Bone cement acts like a grout and not so much like a glue in arthroplasty. Although sticky, it primarily fills the spaces between the prosthesis and the bone preventing motion. It has a Youngs modulus between cancellous bone and cortical bone. Thus it is a load sharing entity in the body not causing bone resorption. [9] ...
Fingerprint Dive into the research topics of Biomechanical behavior of novel composite PMMA-CaP bone cements in an anatomically accurate cadaveric vertebroplasty model. Together they form a unique fingerprint. ...
Polymer modified calcium phosphate cements made with cement powders of varying tetracalcium phosphate [TTC P] content were prepared using two different molecular weight fractions of poly(acrylic acid)
Hydroxyapatite cement was investigated in situ for the reconstruction of juxta-articular defects. Polymethylmethacrylate is currently the most commonly used material for the reconstruction of bone defects following the exteriorization and curettage of aggressive benign tumors. In vitro, we compared the effects of hydroxyapatite cement and polymethylmethacrylate in restoring the stiffness of the subchondral plate in a caprine femoral defect model. Ten matched pairs of caprine femora underwent nondestructive compression testing normal to the load-bearing surface. A standardized subchondral defect 12 mm in diameter was created in the medial femoral condyle. Compression testing was repeated to determine the reduction in stiffness caused by the defect. Each femur from each pair was randomly assigned to one of two groups (n=9), and the defects were augmented with either polymethylmethacrylate or hydroxyapatite cement. After 12 hours, compression testing was repeated to determine the subchondral stiffness
About Heraeus Medical. Heraeus Medical is a leader in the area of bone cements and biomaterials for surgical orthopaedics and trauma surgery. This enables the company to make an important contribution to supporting surgeons and the surgical team and to improve surgery outcomes. In the area of biomaterials, Heraeus Medical focuses on products for use in bone and joint surgery. The core product PALACOS® is considered the gold standard among bone cements and has repeatedly proven itself for over 60 years of clinical use. The first bone cement with antibiotic for infection prophylaxis in endoprosthetics was developed more than 45 years ago with PALACOS® R+G.. About Heraeus A globally leading technology group, Heraeus is headquartered in Hanau, Germany. Founded in 1851, it is a family-owned portfolio company which traces its roots back to a pharmacy opened by the family in 1660. Today, Heraeus combines businesses in the environmental, energy, electronics, health, mobility and industrial ...
After diagnosis of infection and informed consent, patients will be taken to the operating room. After anesthetization, patients will be randomized to either an articulating spacer or static spacer. Randomization will be performed by prepared opaque envelopes administered by a nonparticipant in the study. After a complete debridement of devitalized tissue, explantation of infected components and any associated cement, either an articulating or static spacer will be placed. All spacers will be formed using 3.0 g of Vancomycin and 1.0 g of Tobramycin for each 40 g packet of cement. Articulating spacers will be formed of antibiotic-impregnated cement using the Stage One system (Biomet, Warsaw, IN) sized to fit the endosteal and acetabular bone defect. Static spacers will be hand-made with a rod of antibiotic-impregnated cement and cement beads of sufficient quantity to fill the acetabulum.. Post-operatively, all patients will be made touch-down weight bearing protected with a walker or crutches. At ...
Autori: zaharia c., moreau m.f., zecheru t., marculescu b., filmon r., cincu c., basle m.f., chappard d. Editorial: 34th european symposium on calcified tissues, copenhagen, 2007.. Rezumat:. Poly(methyl methacrylate -pMMA) is used as dental or bone cement. A major drawback of the polymeric biomaterials is that they are radiolucent since they hardly absorb X-ray radiation due to the absence of heavy elements within their structure ...
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Class Action Lawsuit Information regarding Bone Cement Implantation Syndrome (BCIS) after hip replacement surgery. Click here or call (866) 588-0600.
Calcium Phosphate Bone Cements. By Erdem Şahin. Biomaterials utilized in biomedical applications are of various characteristics and cements are unique in their in situ, biomimetic formation ability. They present the most topographically complex surfaces that usually elicit a favorable cellular response for tissue regeneration. In addition their composition may provide an effective chemical gradient around the resorbing implant to induce desired cellular activity that leads to rapid wound healing and regeneration. These are the main reasons for many cement systems to function well in the body, especially as hard tissue replacements. The properties and the setting mechanisms of the clinically most relevant cement system, calcium phosphate cements have been elucidated in this chapter.. Part of the book: Cement Based Materials ...
Finally, I wonder how much my forehead can be protrude by surgery. You know I am Asian, and I want to make my forehead and brow bone protrude as much as a Caucasian, if its possible. I really want to know whether its possible or not.. A: I have done forehead and brow bone augmentation over my career by every conceivable method including PMMA and hydroxyapatite bone cements, prefrormed Medpor implants and, more recently, custom forehead and brow bone implants.. Each of these methods have their own distinct advantages and disadvantages…neither one is perfect. Bone cements are very good to use but they require a lot of intraoperative shaping, can be very expensive (HA cements) and can lead to frontal bossing/protrusions if the forehead and brow bones is brought too far forward. (as bone cements should not extend beyond the anterior temporal lines onto the tenporalis muscle fascia where they will not adhere and can lead to visible edging). To place them well, they require a long coronal incision ...
TABLE-US-00019 TABLE 16 Compressive strength (MPa) values of TTCP/DCPA/CSH composite porous blocks prepared from TTCP/DCPA/CSH/KCl (pore-forming agent)-mixed powders mixed with 0.6M (NH4)2HPO4 (L/P = 0.33 cc/g) Impregnated in Impregnated in TTCP/ Without Without 1M (NH4)2HPO4, 1M (NH4)2HPO4, DCPA:CSH impregnation impregnation at 37° C. for 1 d at 37° C. for 1 d (weight TTCP/DCPA/CSH:KCl = TTCP/DCPA/CSH:KCl = TTCP/DCPA/CSH:KCl = TTCP/DCPA/CSH:KCl = ratio) 1:1 (weight ratio) 1:2 (weight ratio) 1:1 (weight ratio) 1:2 (weight ratio) 90:10 4.86 ± 0.43 0.92 ± 0.18 8.43 ± 0.73 1.62 ± 0.28 85:15 5.00 ± 0.64 0.82 ± 0.23 7.29 ± 0.54 1.22 ± 0.19 75:25 4.18 ± 0.49 0.74 ± 0.10 7.03 ± 0.49 0.98 ± 0.18 65:35 3.74 ± 0.42 0.51 ± 0.07 5.19 ± 0.26 0.91 ± 0.05 55:45 2.36 ± 0.19 0.42 ± 0.06 4.01 ± 0.56 0.71 ± 0.10 Impregnated in Impregnated in TTCP/ 1M K2HPO4, 1M K2HPO4, DCPA:CSH at 37° C. for 1 d at 37° C. for 1 d (weight TTCP/DCPA/CSH:KCl = TTCP/DCPA/CSH:KCl = ratio) 1:1 (weight ratio) 1:2 ...
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Laboratory bench tests have shown that porosity reduction increases the fatigue life of bone cement specimens. Clinically, however, the effect porosity reduction is subject to debate. We hypothesized that the discrepancy between clinical and experimental findings is related to differences in the stress distribution, which is typically uniform in experimental test specimens, while stress concentrations exist in cement around hip implants. We simulated fatigue failure of cement in a finite element model of an experimental test specimen and of a transverse slice of a total hip arthroplasty with a sharp-cornered stem. Four levels of porosity were introduced. In the fatigue test specimen model, the fatigue life clearly was dependent on the level of porosity, while in the transverse slice model, the level of porosity had virtually no effect on failure of the cement mantle. The results of the simulations confirmed our hypothesis. In simulations of laboratory tests, pores clearly acted as crack ...
Bone Cement & Glue Market Research: Global Status & Forecast by Geography, Type & Application (2015-2025) is a market research report available at US $2280 for a Single User PDF License from RnR Market Research Reports Library.
Zimmer Biomet offers bone cement options and a broad spectrum of surgical equipment designed to save time and money in the operating room.
Zimmer Biomet offers bone cement options and a broad spectrum of surgical equipment designed to save time and money in the operating room.
Bone Cement - MedDirect is NZs No.1 Online Medical Product Directory - find New Zealand Medical Companies supplying products you are looking for.
Polymethyl-methacrylate (PMMA) as part of bone cement is a widely used material in the context of orthopaedic implants and also in cranioplasty. Although PMMA is characterised by excellent biocompatibility with low intrinsic toxicity and inflammatory activation, a minor portion of patients develop allergic reactions. We present the case of a 39-year-old woman with an increasing headache and a corresponding erythema over the parieto-occipital cranioplasty, which was performed 42 days prior using a PMMA compound. A patch test specific for bone cement components confirmed the diagnosis of a PMMA delayed-type hypersensitivity reaction. The prevalence of allergic reactions to bone cement components are known to vary from between 0.6% and 1.6%, however no adequate, pre-interventional diagnostic tool is currently available. Therefore, physicians are required to consider this differential diagnosis even after an extremely delayed onset of symptoms. This case describes the first ever-reported case in the ...
Fingerprint Dive into the research topics of Effect of cement volume on the strength and stiffness of vertebral bodies after vertebroplasty: Ex vivo evaluation. Together they form a unique fingerprint. ...
Arthroscopic revision of rotator cuff lesions is an increasingly popular procedure with a relatively safe profile. However, associated deep articular infection has been described, with potentially destructive joint sequelae. When occurring, it poses
Cement; Wolverine (November 21, 1992) Cockroaches; Broken Bones; Dentist Chair; Rhinoceros (November 28, 1992) Omnimax ... Funny Bone Chat; Onions & Tears Chat (November 19, 1983) Color Blindness; Taste Buds; Black Hole Chat (November 26, 1983) ... Bone Marrow; King's Singers; Rotting Foods (December 9, 1995) Wild Lion Vet; Bicycles; Fish Breathing; Insect Warfare (December ... Bones; Coyotes (December 28, 1996) Wetlands; Eco-Filtration; Drinking Water; Water Tower (January 4, 1997) Lost World Dinosaurs ...
She is currently editing a book on Bone Cements by the Woodhead Publishing UK (Journal). Her profile on ORCID can be found here ... Deb, S. (2008). Orthopaedic Bone Cements. Elsevier. ISBN 978-1-84569-517-0. Deb, S., ed. (2015). Biomaterials for Oral and ... "Curently editing a book on Bone Cements: Woodhead Publishing UK (Journal) - Research Portal, King's College, London". kclpure. ... Palmer, Richard M. Evaluation of a β-Calcium Metaphosphate Bone Graft Containing Bone Morphogenetic Protein-7 in Rabbit ...
Anselmetti, Giovanni Carlo (June 2010). "Osteoplasty: Percutaneous Bone Cement Injection beyond the Spine". Seminars in ... It is the surgical alteration or reshaping of bone. It may be used to relieve pain associated with metastatic bone disease.[ ... Osteoplasty is the branch of surgery concerned with bone repair or bone grafting. ... Percutaneous osteoplasty involves the use of bone cement to reduce pain and improve mobility. Resection osteoplasty is used in ...
The haversian canal contains the bone's blood supplies. The boundary of an osteon is the cement line. Each haversian canal is ... Haversian canals Cortical bone (compact bone) Cancellous bone (spongy bone) Ross, Lawrence M.; Lamperti, Edward D., eds. (2006 ... Bone [dead link] - BioWeb at University of Wisconsin System Histology of osteons "Video ... In bioarchaeological research and in forensic investigations, osteons in a bone fragment can be used to determine the sex of an ...
... Medical manufactures bone cements and develops coatings for medical implants. Its products are used in orthopedic ...
Bone cement has been the material most often used, in spite of its tendency to slippage and resorption, and a consequent high ... Resurfacing with calcium phosphate bone cement". Australian Journal of Otolaryngology. 4 (3): 167-173. Teixido, Michael; ... the gap in the temporal bone can be repaired by surgical resurfacing of the affected bone or plugging of the superior ... A clinical sign of this phenomenon is the ability of the patient to hear (not feel) a tuning fork placed upon the ankle bone. ...
The basin is made of cement and tile. The dimensions of the sculpture are 9'6" × 4' × 4'. The dimensions of the fountain basin ... Instruments consist of saxophones, sousaphones, trombones, trumpets, and tubas. The sculpture sits in a fountain basin, which ...
According to the indictment, before the marketing program began, pilot studies showed the company that the bone cement reacted ... In October 2010, Synthes and its subsidiary Norian both plead guilty to crimes relating to illegally implanting bone cement ... firm to pay $23M for illegal bone cement tests". Yahoo News/Associated Press. Retrieved 2010-10-05. CS1 maint: discouraged ... In 2009 the U.S. attorney in Philadelphia accused the company of illegally promoting a bone void filler for unapproved uses, ...
Bone cement acts like a grout and not so much like a glue in arthroplasty. Although sticky, it does not bond to either the bone ... In orthopedic surgery, PMMA bone cement is used to affix implants and to remodel lost bone. It is supplied as a powder with ... A disadvantage of this bone cement is that it heats up to 82.5 °C (180.5 °F) while setting that may cause thermal necrosis of ... "Low-modulus PMMA bone cement modified with castor oil". Bio-Medical Materials and Engineering. 21 (5-6): 323-332. doi:10.3233/ ...
In medicine, it is used in bone cement and to replace eye lenses. Acrylic paint consists of PMMA particles suspended in water. ...
The bones were crushed on cement with mallets and added to the ashes. These were transported every night in sacks made of ... Eventually, the camp authorities bought a bone-crushing machine (Knochenmühle) from Schriever and Co. in Hamburg to speed up ...
Gruber, H. E.; Mekikian, P. (1991). "Application of stains-all for demarcation of cement lines in methacrylate embedded bone". ... It is used in SDS-PAGE, agarose gel electrophoresis and histologic staining, e.g. staining of growth lines in bones. Green, M. ...
DTA may be used in cement chemistry, mineralogical research and in environmental studies. DTA curves may also be used to date ... "The application of differential thermal analysis and thermogravimetric analysis to dating bone remains". Journal of Forensic ... Ramachandran V.S. "Applications of differential thermal analysis in cement chemistry". Chap. V, Chemical Publishing Co., Inc., ... bone remains or to study archaeological materials. Using DTA one can obtain liquidus & solidus lines of phase diagrams. ...
4-7-year stereoradiographic follow-up of 84 cemented prostheses". The Journal of Bone and Joint Surgery. British Volume. 76 (6 ... Two synchronised x-ray foci are used to obtain a stereo image of the bone and the prosthesis. The positions of the foci are ... To achieve the high accuracy, the following steps are carried out: Small radio opaque markers are introduced in the bone and ... The coordinates of the bone and prosthesis markers are accurately measured and the three-dimensional position of the markers is ...
A cement line demarcates articular calcified cartilage from subchondral bones.[citation needed] Once damaged, cartilage has ... Bone morphogenetic proteins are growth factors released during embryonic development to induce condensation and determination ... This temporary cartilage is gradually replaced by bone (Endochondral ossification), a process that ends at puberty. In contrast ... and new bone produced in the vascular space in a process similar to endochondral ossification at the physis. ...
The cement that reflected these features was produced by CMW Laboratories Limited and was called CMW bone cement. Charnley also ... Charnley was convinced that the best way to fix the prosthesis into the femur was to use bone cement that acted as a grout ... His first attempt consisted in introducing antibiotics such as gentamicin into the bone cement; the number of bacteria ... He was resident in the hospital for six months in 1946, during which he developed his interest in bone grafting. In order to ...
The cement can be used for fixing bone grafts, bone filling and repairing the loss due to osteoporosis. She works for the Sree ... The 10th award was in 2020 and it was for her novel bone cement. (with Krishnan, V.K.) A comparison of efficiency of two ... She was recognised particularly for developing a bone cement which can also be used as a cheaper alternative to dental fillings ...
The femoral, tibial and patella components of a total knee replacement are fixed to the bone by either using cement or ... cement. Alternative techniques exist that affix the implant without cement. These cement-less techniques may involve ... The ends of these bones are then accurately cut to shape using cutting guides oriented to the long axis of the bones. The ... On the tibia the component is flat, although it sometimes has a stem which goes down inside the bone for further stability. A ...
Loosening of the components: the bond between the bone and the components or the cement may break down or fatigue. As a result ... cement. Alternative techniques exist that affix the implant without cement. These cement-less techniques may involve ... The ends of these bones are then accurately cut to shape using cutting guides oriented to the long axis of the bones. The ... the component moves inside the bone, causing pain. Fragments of wear debris may cause an inflammatory reaction with bone ...
... hundreds of sculptures made from chicken bones, ceramic and cast cement; pin-up style photos of his wife, Marie; plus dozens of ... in leftover chicken and turkey bones. Architecturally imposing bone structures resulted. After soaking the bones in ammonia and ... This time, however, his paintings were informed by the decade he spent constructing architectural bone sculptures. His later ... The exhibit, entitled "Eugene Von Bruenchenhein: Freelance Artist-Poet and Sculptor-Inovator-Arrow maker and Plant man-Bone ...
Cement from Kandos Cement Works was a regular source of traffic until the work's closure in 2011. Grain was formerly shipped ... Primary traffic on the line today is coal trains from the Airly Colliery following the closures of the Baal Bone and Charbon ... "Kandos Cement Plant". Cement Australia. Retrieved 16 September 2018. "Harvest stopped dead in its tracks". The Sydney Morning ... Coal operations were initiated by the State Rail Authority at Baal Bone in July 1986 and at Charbon in December 1986. Charbon ...
Nebiros is slain due to Firestorm changing the water in his body to cement. Faust regains his soul. The combined forces of the ... Not willing to risk Blue Devil's safety, he eliminates the magical connection by plunging the last of Blue Devil's bones into ... In battle, Faust releases Blue Devil, whose bones he had apparently bought from a mysterious marketplace. ...
"Technological issues for the development of more efficient calcium phosphate bone cements: A critical assessment". Biomaterials ... is a component used in the formation of some hydroxyapatite calcium phosphate cements that used for the repair of bone defects ... One example of a hydroxyapatite cement forming reaction is that of tetracalcium phosphate and dicalcium diphosphate dihydrate: ... Tetracalcium phosphate is a component in some calcium phosphate cements that have medical applications. Tetracalcium phosphate ...
The pin was held in place by an organic resin, analogous to modern bone cement. By doing so, those who performed the operation ...
Many different types of glue held these sections together, most commonly Irish glue and bone glue. This was until hilton glue, ... or cement glue, was introduced because of its waterproof qualities. Even today, Tonkin split-bamboo rods are still popular in ...
... "splint bones". They are the remnants of the second and the fourth toe. Modern horses retain the splint bones; they are often ... Eohippus, with left forefoot (third metacarpal colored) and tooth (a enamel; b dentin; c cement) detailed ... William Clark's 1807 expedition to Big Bone Lick found "leg and foot bones of the Horses", which were included with other ... However, all of the major leg bones were unfused, leaving the legs flexible and rotatable. Its wrist and hock joints were low ...
... to immobilize broken bones, or for metal casting). Mixed with polymers, it has been used as a bone repair cement. Small amounts ... It has been used in bone regeneration as a graft material and graft binder/extender and as a barrier in guided tissue ... Titus, Harry W.; McNally, Edmund; Hilberg, Frank C. (1933-01-01). "Effect of Calcium Carbonate and Calcium Sulphate on Bone ... Taylor H.F.W. (1990) Cement Chemistry. Academic Press, ISBN 0-12-683900-X, pp. 186-187. "About tofu coagulant". www. ...
Use of the bone cement resulted in the deaths of three people. Wyss was not indicted, but four top executives of Synthes were ... Attorneys for Eastern Pennsylvania for using an untested calcium-phosphate-based bone cement on human patients without ... "Bad to the Bone - a Medical Horror Story",, 18 September 2012. "Three people died in illegal human experiments ... a medical device manufacturer making internal screws and plates for broken bones. In an early initiative, Wyss opened a Synthes ...
"While time hardens cement, at this age, it does not heal bones". "K S Sudarshan: Born into RSS". " ...
Bioclastic phosphates or bone beds: Bone beds are bedded phosphate deposits that contain concentrations of small skeletal ... Bioclastic phosphates can also be cemented by phosphate minerals. Phosphatization: Phosphatization is a type of rare diagenetic ... The bones and teeth of certain fish (e.g. anchovies) absorb phosphorus and are later deposited and buried in the ocean sediment ... It is also present as hydroxyapatite Ca5(PO4)3OH or Ca10(PO4)6(OH)2, which is often dissolved from vertebrate bones and teeth, ...
This is accomplished by the exchange of natural bone constituents, deposition in voids or defects, adsorption onto the bone ... After deposition, sediments are compacted as they are buried beneath successive layers of sediment and cemented by minerals ... Due to the increase in porosity of bones through collagen loss, the bone becomes susceptible to hydrolytic infiltration where ... 2002). "The Survival of Organic Matter in Bone: A Review". Archaeometry. 44 (3): 383-394. doi:10.1111/1475-4754.t01-1-00071.. ...
Animal dung occasionally is used as a cement to make adobe mudbrick huts,[19] or even in throwing sports such as cow pat ... These are studied to determine the diet and health of the people who produced them through the analysis of seeds, small bones, ...
Environment Agency record of proposal to use Meat & Bone meal as a power source ... Lafarge Cement UK bought Blue Circle industries PLC in 2001, creating the largest cement maker in the world. Cement from the ... Aberthaw Cement Works are cement works in the Vale of Glamorgan near the village of Aberthaw in Wales. ... The Aberthaw and Bristol Channel Portland Cement Company was established in 1912 by the Beynon family. The site at Aberthaw was ...
Later, when lead-making and bone-processing for soap and china came to be established, they too located in the East End rather ... Prefabricated post-war home at Chiltern Open Air Museum: Universal House, steel frame clad with corrugated asbestos cement ...
This was until hilton glue, or cement glue, was introduced because of its waterproof qualities.[4][5][6] Even today, Tonkin ... Many different types of glue held these sections together, most commonly Irish glue and bone glue. ...
... most famous song and a performance of it on Top of the Pops cemented their national fame.[63] It gave them their first top ten ... Paul Oakenfold and Frankie Bones, a Zimbabwean drum orchestra, and the reggae artist Gary Clail.[70] The event, considered a ... and when he agreed the band's line-up was cemented.[19] Leaving their previous bands behind, they worked solely on new material ...
... to immobilize broken bones, or for metal casting). Mixed with polymers, it has been used as a bone repair cement. Small amounts ... a b Taylor H.F.W. (1990) Cement Chemistry. Academic Press, ISBN 0-12-683900-X, pp. 186-187. ... In flue-gas desulfurization, exhaust gases from fossil-fuel power stations and other processes (e.g. cement manufacture) are ... a mineral phase essential in cement clinker production.[11] ...
Surgical resection Radiation therapy Sclerotherapy Percutaneous bone cement Bone graft Prosthesis Surgical stabilization ... As the disease progresses bone deformity occurs with further loss of bone mass and, in the tubular bones (the long bones of the ... Massive osteolysis (acute spontaneous absorption of bone, phantom bone, disappearing bone): its relation to hemangiomatosis. J ... complete or near-complete resorption of the bone occurs and may extend to adjacent bones, though spontaneous arrest of bone ...
... through which he cementing connections with scholars across Europe.[42] His job made him well known in Britain's small ... were respectable while stone and bone tools were banausic." ...
Bird bones are not infrequently encountered compared to other lagerstätten, but usually occur as single bones and are often ... These have been used in the past for making cement. They were once dug for this purpose at Sheppey, near Sittingbourne, and at ... bones Primapus - a swift-like bird Primodroma - a tubenose, possibly a storm-petrel Prophaeton - a tropicbirds relative ...
... both of which were fixed to the bone using PMMA (acrylic) bone cement. For over two decades, the Charnley Low Friction ... He found that joint surfaces could be replaced by implants cemented to the bone. His design consisted of a stainless steel one- ... The Journal of Bone and Joint Surgery. Needham, MA. 88 (3): 660-667. doi:10.2106/JBJS.E.01208. PMID 16510834. Retrieved ... However, traction was the standard method of treating thigh bone fractures until the late 1970s when the Harborview Medical ...
The limb bones were also very robust.[9] The arm bones are stout, with the humerus resembling that of Camarasaurus, and those ... helped cement Brontosaurus as a quintessential dinosaur in the public consciousness.[56] ... The hip bones included robust ilia and the fused pubes and ischia. The tibia and fibula bones of the lower leg were different ... The material of this specimen, CM 566, includes vertebrae from various regions, one pelvic bone, and some bones of the hind ...
It was determined that Timur was a tall and broad-chested man with strong cheek bones. At 5 feet 8 inches (173 centimeters), ... Khorasan revolted one year later, so Timur destroyed Isfizar, and the prisoners were cemented into the walls alive. The next ...
Bone, both human and animal, was also sculpted; human bones may have been trophies, or relics of ancestors.[191] The Maya ... Limestone was burned at high temperatures in order to manufacture cement, plaster, and stucco.[227] Lime-based cement was used ... Puuc sites replaced rubble cores with lime cement, resulting in stronger walls, and also strengthened their corbel arches;[264] ...
High grade limestone (used in the manufacture of cement, lime, sugar and paper) occurs in the district and is mined extensively ... bones etc. Scope of forestry is enormous in this district and Forest Department is taking care of this aspect for economic use ...
It consists of a mass of very hard, hair-like filaments cemented together around a spongy internal core. This layering affect ... Bone is never soaked. Bone, antler, and horn objects are stored in tightly closed display cases or drawers to buffer them from ... Antler, which is a modified form of bone, grows out of the skull bones of certain species of animals and is shed once a year. ... It consists of a thick layer of compact bone, an inner section of spongy bone, and internal blood vessels that are less and ...
Bone, James (2009-12-03). "Climate scientist James Hansen hopes the summit will fail". Timesonline. London. Retrieved 2009-12- ... notably cement manufacturers and farmers.[182] Nevertheless, the tax generated sufficient praise to attract broad attention in ... cement, paper, chemical, gas, electric power, auto manufacturing and electronics, and information technology sectors. The ...
It is applied to the back using diluted rubber cement (using benzene as the solvent). No sights or other modern attachments are ... Oracle bone script version of the yi character. The reflex bow had been the most important weapon in Korean wars with Chinese ...
Potassium carbonate is used to produce animal feed supplements, cement, fire extinguishers, food products, photographic ... Bone ash. *List of mines in Saskatchewan. ReferencesEdit. *^ a b c d Potash, USGS 2008 Minerals Yearbook ...
In cement mixes, mortars, concrete, grouts[edit]. Sodium hydroxide is used in some cement mix plasticisers. This helps ... and the only solid that remains are bone hulls, which could be crushed between one's fingertips.[33] Sodium hydroxide is ... homogenise cement mixes, preventing segregation of sands and cement, decreases the amount of water required in a mix and ... increases workability of the cement product, be it mortar, render or concrete. ...
However, it can slightly affect restorations made with composite materials, cements and dental amalgams. Tooth whitening will ... and bone.[26] Ingestion during the years of tooth development causes yellow-green discoloration of dentine visible through the ... Glass ionomer and other cements - studies suggest that solubility of these materials may increase.[62] ...
... , also known as glue, cement, mucilage, or paste,[1] is any non-metallic substance applied to one or both surfaces of ... Egg-based pastes were used to bond gold leaves incorporated various natural ingredients such as blood, bone, hide, milk, cheese ... This material, known as pozzolanic cement, was used in the construction of the Roman Colosseum and Pantheon.[13] The Romans ... White glue, contact adhesives and rubber cements are members of the drying adhesive family. As the solvent evaporates, the ...
Osteoporotic bone marrow defect. *Paget's disease of bone. *Periapical abscess *Phoenix abscess ... Glass ionomer cements Composites Dentin bonding agents Lasers. Neodymium:yttrium aluminum garnet (Nd:YAG) laser ...
"Haunted" Maya Underwater Cave Holds Human Bones". Retrieved 24 June 2019.. *^ Rock, Tim (2007). Diving & Snorkeling Belize (4th ... groundwater may dissolve the carbonate cement holding the sandstone particles together and then carry away the lax particles, ...
The deal cemented Pfizer's position as the largest pharmaceutical company in the world, with the merged company generating over ... The medicine, called Bosulif, treats chronic myelogenous leukemia (CML), a blood and bone marrow disease that usually affects ...
... sometimes used as a portal of entrance into the vertebral body for fixation with pedicle screws or for placement of bone cement ... Position of human lumbar vertebrae (shown in red). It consists of 5 bones, from top to down, L1, L2, L3, L4 and L5. ...
The bones of frigatebirds are markedly pneumatic, making them very light and contributing only 5% to total body weight. The ... The nest is subsequently covered with (and cemented by) guano. Frigatebirds prefer to nest in trees or bushes, though when ... A cladistic study of the skeletal and bone morphology of the classical Pelecaniformes and relatives found that the frigatebirds ... pectoral girdle is strong as its bones are fused. The pectoral muscles are well-developed, and weigh as much as the ...
The bones were recovered and buried under the name "John Bones Doe". At the time, a pathology report on the bones indicated ... On the night of June 11, 1962, with all preparations in place, the men began their escape.[17] However, the cement employed to ... "John Bones Doe", and DNA from the bones was compared to a DNA sample from one of Morris's paternal relatives. The DNA did not ... "John Bones Doe"; It was not a match and so the bones did not belong to either Anglin brother. ...
At the bone marrow, transferrin is reduced from Fe3+ and Fe2+ and stored as ferritin to be incorporated into hemoglobin.[136] ... It is also used to reduce chromate in cement. It is used to fortify foods and treat iron deficiency anemia. Iron(III) sulfate ...
... be appropriate to tie vertical wall elements into the foundation using specialty connectors and bolts glued with epoxy cement ... dog-bone' shape flange.[26] ...
Our market leading Hydroxyapatite bone cements for cranial applications provide you with flexible delivery systems to assist ... Bone cements. Setting the standard in HA bone cements.. Our market leading Hydroxyapatite bone cements for cranial applications ...
Due to its cementing properties, 4MATRIX can be used with or without membrane coverage, reducing working time and costs. ... Optimal Bone Regeneration: During the augmentation procedure, the biphasic calcium sulfate component of 4MATRIX remains intact ... The Biphasic Calcium sulfate completely degrades in strict relation to the bone formation rate (4-10 weeks), while the HA acts ... Advanced composition, simplicity and ease of use: These terms best describe the new 4MATRIX Bone Graft solution delivered by ...
The invention relates to surgical bone cement compositions and more particularly to bone cement compositions having aneasthetic ... Bone cement was temporarily applied to keep the bones spaced and aligned, but this time the cement was Howmedica bone cement ... bone cement powder (40 g)+bone cement liquid (17.9 g)=57.95 g. The mean mass of bone cement discs in an individual experiment ... released from said bone cement composition when the bone cement composition is in a subject and the strength of the bone cement ...
... During balloon kyphoplasty, bone cement (often a pasty compound called PMMA) is ...
... polymeric bone cements, are provided. A feature of the subject methods is that vibration is employed in conjunction with the ... use of the cement, e.g., in preparation of the cement, in preparation of the target site, in delivery of the cement to the ... target site, and/or following delivery of the cement to the target site. Also provided are devices, systems and kits that find ... Methods of employing bone defect filling, e.g., ... bone cement (Zimmer); the CMW™ bone cement (Depuy); the ...
An orthopaedic bone cement mixing device comprising a mixing bowl (1) and a lid (3), said lid (3) having a handle (4) extending ... Automated bone cement mixing apparatus. US6033105 *. 4. Aug. 1999. 7. M rz 2000. Barker; Donald. Integrated bone cement mixing ... Method of mixing bone cement with two mixing paddles. US7967499. 12. Jan. 2010. 28. Juni 2011. Stryker Corporation. Bone cement ... Bone cement mixing apparatus. EP1068893A3 *. 14. Juli 2000. 5. Dez. 2001. DePuy Orthopaedics Inc.. Bone cement mixing apparatus ...
Injecting a calcium-based cement into the bones of some people with knee or hip pain could help them avoid joint replacement ... The cement braces the bruised or injured joint bone from the inside, Vasileff explained, and eventually is replaced by new bone ... "We dont want to send the message to people who have bone-on-bone, with big bone spurs and limited range of motion that theyre ... 11, 2018 (HealthDay News) -- Injecting a calcium-based cement into the bones of some people with knee or hip pain could help ...
... are anchored with bone cement. The bone cement fills the free space between the prosthesis and the bone and plays the important ... Bone cements are provided as two-component materials. Bone cements consist of a powder (i.e., pre-polymerized PMMA and or PMMA ... If the patient is known to have any allergies to constituents of the bone cement, according to current knowledge bone cement ... Anchorage without cement - cement-free implant placement - is the alternative. New bone cement formulations require ...
Such a bone cement formulation decreases the exothermic temperature of the bone cement and decreases the possibility of tissue ... Therefore, a reduced amount of a polymerizable component need be added to the dry component to form a bone cement. ... A bone cement having a dry component including a large constituent and a small constituent. The small constituent fills a ... Bone cement containing bone marrow. WO2011109684A1. 4 Mar 2011. 9 Sep 2011. Synthes Usa, Llc. Bone cement system for bone ...
Injecting a calcium-based cement into the bones of some people with knee or hip pain could help them avoid joint replacement ... The cement braces the bruised or injured joint bone from the inside, Vasileff explained, and eventually is replaced by new bone ... "We dont want to send the message to people who have bone-on-bone, with big bone spurs and limited range of motion that theyre ... The calcium phosphate cement flows into the spongy inside portion of the bone, filling in microfractures and other damaged ...
Material scientists at the University of Jena have developed a bone replacement based on calcium phosphate cement and ... For this reason, calcium phosphate cement has so far mainly been used on bones that do not play a load-bearing role in the ... Material scientists at the University of Jena have developed a bone replacement based on calcium phosphate cement and ... However, doctors often have to lend a helping hand to repair bones after a fracture or due to a defect. Increasingly, bone ...
OrtoWay develops innovative surgical tools used in spinal surgery.The Company was established in October 2006 by a group of five experts in biomaterials, spi...
... ... 3.2.1 Bone Cement Market, China, Revenue ($m), by Segment, 2005-2012 11. 3.2.2 Bone Cement Market, China, Revenue ($m), by ... 3.4 Orthopedic Bone Cement and Casting Materials Market, China, Volume (Units), 2012-2020 17. 3.4.1 Bone Cement Market, China, ... 3 Orthopedic Bone Cement and Casting Materials Market, China 7. 3.1 Orthopedic Bone Cement and Casting Materials Market, China ...
The system includes a mixing cartridge for receiving liquid and powder components of bone cement, a mixing device for mixing ... and a delivery gun for discharging the bone cement from the mixing cartridge. The mixing cartridge comprises a cylinder having ... A bone cement mixing and delivery system is provided. ... 32, a bone cement loading system is shown. The bone cement ... A bone cement mixing and delivery system for combining liquid and powder components of bone cement and delivering the bone ...
Bone Etched Cement is a large scale concrete grid like pattern in a light grey. Approximate Design Repeat Length*: 8.9 ... Bone Etched Cement Y0421 Promoted Finish. 07 Textured Gloss FINISH Y0421 Features. *. Large-Scale Pattern. This is a large- ... Bone Etched Cement is a large scale concrete grid like pattern in a light grey. ... Bone Etched Cement is a large scale concrete grid like pattern in a light grey. ...
In the pristine cement powders, Ag in its metallic form was found, whereas for CPC-Ag 0.6 wt % and CPC-Ag 1.0 wt % cements, ... The CPC-Ag 0 wt % cement exhibited a compressive strength of 6.5 ± 1.0 MPa, whereas for the doped cements (CPC-Ag 0.6 wt % and ... cements, better performances being observed for the cement with a higher Ag-content. ... Silver-ion release from CPC-Ag 0.6 wt % and CPC-Ag 1.0 wt % cements, measured by the Atomic Emission Spectroscopy, corresponds ...
Jens Chapman did not act below the standard of medical care when he used the Norian bone cement on Reba Golden's back in ... Jury sides with surgeon in bone cement trial. Published August 8, 2016. ... of Washington surgeon who was sued by the daughter of a patient who died after the doctor used a non-FDA-approved bone cement ... but concluded that an informed person would have opted to use the cement anyway.. Wilson had also sued Synthes, the maker of ...
... Materials Market 2026 with the Current State of the Industry, Major ... Bone cement is a material used for the fixation of joint implants to the bone. Chemical bone cement is Plexiglas, which is a ... which is found naturally in bones and teeth. The recently approved bone cement has been used successfully in 4,000 operations ... which makes the use of antibiotic bone cements essential. Casting materials are used for supporting broken or injured bone. ...
... into lesions in patients whose cancer has spread to their bones can allow these individuals to live the remainder of their ... Bone cement eases cancer pain. Injecting "bone cement" into lesions in patients whose cancer has spread to their bones can ... Osteoplasty involves injecting bone cement (here they used polymethyl-methacrylate or PMMA) into a bone lesion with the help of ... Injecting "bone cement" into lesions in patients whose cancer has spread to their bones can literally allow these individuals ...
Compact bovine bone subjected to constant torsional load for long periods of time exhibits large anelastic effects. ... Displacements occur at the cement lines and are responsible for part or all of the long-term deformation. The absence of an ... asymptotic creep strain is consistent with an interpretation of the cement line as a viscous interface. ...
You have invented a new elastic bone cement for spinal fractures. How will it be used? ... "We began with an existing bone cement and added a softener that gives the bone cement some new and different characteristics, ... Elastic bone cement for those with brittle bones Hello there, Cecilia Persson, researcher in biomaterials and biomechanics at ... Today, the bone cement thats injected is mainly an effective pain relief treatment. The problem is that the cement is very ...
... Growth During 2018 ? 2025: Global Players 3M, Orthofix, Zimmer & ... In addition, bone cement provides bone stability during internal fixation surgery. Growing older population promotes market ... Bone fixation is a surgical procedure that stabilizes and fix bone grafts and bone filling… ... Bone Implant Market Gaining Momentum Worldwide - CT-Bone, 3D printed Bone Implan … ...
The cement paste (55.86 ± 0.23) obtained higher bone-to-implant contact (BIC) percentage values (better quality, closer contact ... The highest BIC and bone formation percentages were obtained on day 60. These results suggest that the cement paste is ... cement. Biphasic α´L + β-C2Sss was synthesized by solid-state processing, and was used as a raw material to prepare the cement ... A porous cement made of the high temperature forms of C2S, with a low phosphorous substitution level, was produced. An apatite- ...
Buy a discounted Paperback of Bone Cements and Cementing Technique online from Australias leading online bookstore. ... Booktopia has Bone Cements and Cementing Technique by G. H. I. M. Walenkamp. ... Bone Cements and Cementing Technique. By: G. H. I. M. Walenkamp (Editor), D. W. Murray (Editor), U. Henze (Editor), H.-J. Kock ... Bone Cement Porosity in Vacuum Mixing Systems. p. 81. Efficacy of a New Prepacked Vacuum Mixing System with Palamed® G Bone ...
Find Bone Cement related suppliers, manufacturers, products and specifications on GlobalSpec - a trusted source of Bone Cement ... Bone-Implant Interface in Orthopedic Surgery The bone-cement interface represents a complex structure of acrylic bone cement ... The Well-Cemented Total Hip Arthroplasty The basic science aspects include properties of bone cement , mixing and bone ... He was the first surgeon to use a cement gun to deliver bone cement , was active in the design of both cemented and uncemented ...
... antibiotic-loaded PMMA bone cements used for vacuum- and hand-mixed cement using a Cemvac vacuum mixing system. We also ... unloaded bone cements after hand-mixing. The porosity of cements was reduced in all vacuum-mixed cements, as compared with hand ... antibiotic-loaded PMMA bone cements used for vacuum- and hand-mixed cement using a Cemvac vacuum mixing system. We also ... The effect of mixing on gentamicin release from polymethylmethacrylate bone cements Acta Orthop Scand. 2003 Dec;74(6):670-6. ...
The bone cement and glue market covers various types of bone cement and glues that are used to fix implants during orthopedic ... On the basis of type, the market is categorized into bone cement and bone glue. The bone glue segment is expected to grow at ... and growth in the demand for bone cement and glue.. Given the immense opportunities in major applications of bone cement and ... The bone cement and glue market is geographically segmented into North America, Europe, Asia Pacific, and the Rest of the World ...
... no difference could be found in the in vivo response to these cements in comparison to the base, commercially available cement ... However, there is no data available on the in vivo biocompatibility of any low-modulus cement. In this study, the in vitro ... Furthermore, the in vivo radiopacity of the cements appeared unaltered. While these results are promising, the mechanical ... which has led to the development of low-modulus cements. ... behavior of these cements in vivo remains to be investigated. ...
Scientists developed a novel bone implant manufacturing method Citation: Bioactive cement scaffold aids bone grafts (2006, ... Bioactive cement scaffold aids bone grafts. U.S. scientists say theyve developed a technology for implants that might improve ... for making scaffolds for bone tissue that is seeded with a patients own cells and formed with a cement paste made of bone ... ... Bioactive cement scaffold aids bone grafts. Your friends email ...
Bone Cement Market report is an overview of the Global Bone Cement Industry It covers all the recent trends including key ... Along with Bone Cement Market research study buyer also gets valuable information about global Bone Cement Production and its ... The Bone Cement Market report provides basic information about Bone Cement industry, definition, classification, application, ... 4.Manufacturing Process Analysis of Bone Cement. This Bone Cement research also includes some of proven effective marketing ...
  • Chemical bone cement is Plexiglas, which is a polymer-based material comprising poly-methyl-methacrylate (PMMA) or co-polymers. (
  • The introduction of the new acrylic bone cements Palamed and Copal is the reason for combining the recent knowledge of some of the experts in the field in this book. (
  • The biocompatibility of acrylic bone cement as it has been traditionally formulated and used has been reported in the literature (1, 2). (
  • Description: also to acrylic resin and other bone cements . (
  • The high stiffness of acrylic bone cements has been hypothesized to contribute to the increased number of fractures encountered after vertebroplasty, which has led to the development of low-modulus cements. (
  • In this study, the in vitro cytotoxicity and in vivo biocompatibility of two types of low-modulus acrylic cements, one modified with castor oil and one with linoleic acid, were evaluated using human osteoblast-like cells and a rodent model, respectively. (
  • In spite of their success in vertebroplasty-they provide pain relief and stability to the fracture site-acrylic bone cements present some issues. (
  • In fact, most commercial acrylic bone cements have an elastic modulus in the range of 1700-3700 MPa [ 9 , 10 ], while the elastic modulus of vertebral trabecular bone is typically in the range of 10-750 MPa [ 11 - 13 ], encompassing osteoporotic to healthy bone. (
  • used aromatic amines as well as acrylic monomers, both derived from oleic acid, to optimize the properties of bone cements [ 14 ]. (
  • Both stem and bone are assumed to be rigidly connected by a layer of acrylic bone cement (PMMA) and the layer taken are of constant cross section. (
  • Porosity of various preparations of acrylic bone cements. (
  • Calcium phosphate cement was used in four cases and acrylic cement in one case. (
  • 5.1 This test method describes a uniaxial, constant amplitude, fully reversed fatigue test to characterize the fatigue performance of a uniform cylindrical waisted specimen manufactured from acrylic bone cement. (
  • The test method can be used to compare different acrylic bone cement formulations and products and different mixing methods and environments (that is, mixing temperature, vacuum, centrifugation, and so forth). (
  • 1.1 This test method describes test procedures for evaluating the constant amplitude, uniaxial, tension-compression uniform fatigue performance of acrylic bone cement materials. (
  • 1.2 This test method is relevant to orthopedic bone cements based on acrylic resins, as specified in Specification F451 and ISO 16402. (
  • It is not the intention of this test method to directly simulate the clinical use of these materials, but rather to allow for comparison between acrylic bone cements to evaluate fatigue behavior under specified conditions. (
  • ISO 16402 Flexural Fatigue Testing of Acrylic Resin Cements Used in Orthopedics Available from American National Standards Institute (ANSI), 25 W. 43rd St., 4th Floor, New York, NY 10036, (
  • The fracture or failure behaviours of four commercial acrylic-based bone cements have been examined in tensile, bending and compression modes, and their mechanical properties are reviewed. (
  • The two major categories of bone cement are nondegradable acrylic bone cements (ABCs) and degradable calcium phosphate cements (CPCs). (
  • In this paper, we report the design of new biantibiotic acrylic bone cements for in situ delivery. (
  • They include a last generation antibiotic (daptomycin or linezolid) in combination with vancomycin and are performed based on a novel modification of the Palacos R® acrylic bone cement, which is based on two components, a liquid (methyl methacrylate) and a solid (polymeric phase). (
  • More recently bone cement has been used in the spine in either vertebroplasty or kyphoplasty procedures. (
  • The procedure is analogous to vertebroplasty, which has been around for a few years, where you put little needles into the spine and inject a cement mixture," Montgomery said. (
  • The bone cement and glue market covers various types of bone cement and glues that are used to fix implants during orthopedic procedures such as arthroplasty, kyphoplasty, vertebroplasty, and several types of fractures. (
  • PMMA-based cements are currently used in a variety of applications, such as joint arthroplasty, percutaneous vertebroplasty, and kyphoplasty [ 3 , 4 ]. (
  • Their high stiffness in comparison to that of cancellous bone results in a property mismatch that has been hypothesized to be a contributing factor to adjacent vertebral fractures occurring shortly after vertebroplasty [ 5 - 8 ]. (
  • Percutaneous vertebroplasty (PVP) is widely used in the treatment of painful osteoporotic vertebral compression fractures with the injection of PMMA cement, and the controversy for PMMA damage to the osteoporotic bone tissue and to affect the fractures repairing never stops. (
  • PMMA would not cause local bone permanent necrosis, and interface injury repairing cycle could be prolonged in a vertebroplasty. (
  • To counter this problem, vertebroplasty device manufacturers are exploring various alternatives to PMMA such as bio-ceramic bone cement , composite resin cement (such as Cortoss by Orthovita), calcium phosphate and calcium sulfate cement, carbonated hydroxyapatite cement, partially absorbable bone cement (Cerament by BoneSupport) and so on. (
  • Reported uncommon short-term complications include infection, cement embolization, and extradural extravasation of the polymethylmethacrylate bone cement (predominately with vertebroplasty), causing nerve root or spinal cord impingement, and in rare cases necessitating decompressive surgery. (
  • In a separate study of vertebroplasty, in vitro evaluations were performed to compare the use of CORTOSS to polymethylmethacrylate (PMMA), the orthopedic bone cement that is widely used "off-label" in vertebral augmentation procedures. (
  • Masala S, Schillaci O, Massari F, Danieli R, Ursone A, Fiori R, Simonetti G. MRI and bone scan imaging in the preoperative evaluation of painful vertebral fractures treated with vertebroplasty and kyphoplasty. (
  • Injectable form of bone cement is being used for various applications in vertebroplasty. (
  • However, in this process, surgeons use special balloons to create spaces within the vertebra that are then filled with vertebroplasty bone cement. (
  • This in turn is increasing the use of vertebroplasty and kyphoplasty bone cement. (
  • Vertebroplasty bone cements should possess a number of properties that differentiate them from total hip arthroplasty (THA) or total knee arthroplasty (TKA) bone cements. (
  • Vertebroplasty bone cement are self-curing compounds that are used in a flowable state with adequate viscosity to be injected efficiently and turn into fully cured cement in the body to deliver sufficient support to the fractured vertebra. (
  • Vertebroplasty bone cement should have substantial mechanical strength and toughness to provide long-term support to the patient. (
  • Vertebroplasty is performed under high contrast X-ray imaging, hence the bone cement needs to be radiopaque to provide clear contrast to the clinician during the surgery. (
  • The global vertebroplasty bone cement market is projected to grow at a steady pace during the forecast period owing to a multitude of factors. (
  • Rise in the number of patients with spinal problems occurring due to accidents, trauma, tumors, sedentary lifestyle, age, and osteoporosis is anticipated to drive the global vertebroplasty bone cement market during the forecast period. (
  • Hence, increase in the number of accidents is expected to propel demand for vertebroplasty bone cement during the forecast period. (
  • Increase in the geriatric population and rise in the number of lifestyle-related disorders are also expected to augment the global vertebroplasty bone cement market. (
  • Major players operating in the global vertebroplasty bone cement market include DePuy Synthes, Stryker Corporation, Teknimed, Heraeus Medical, DJO Global, and Zimmer Biomet. (
  • This is necessary because the human hip is acted on by approximately 10-12 times the body weight and therefore the bone cement must absorb the forces acting on the hips to ensure that the artificial implant remains in place over the long term. (
  • The cement paste (55.86 ± 0.23) obtained higher bone-to-implant contact (BIC) percentage values (better quality, closer contact) in the histomorphometric analysis, and defect closure was significant compared to the control group (plastic). (
  • The implant is further reinforced to about the same strength as spongy natural bone by covering it with several layers of a biodegradable fiber mesh already used in clinical practice. (
  • It works by filling the empty space between the bone and an implant, which anchors the joint. (
  • But many people have experienced the devastating pain of implant failure after bone cement failed to perform as desired. (
  • Some big-name bone cement products have been linked to a loosening of the implant in which its used to secure and in incidences of BCIS. (
  • It happens when the implant is attached to the tibia bone more-so than the femur. (
  • The three-dimensional finite element model of the proximal femur with initial bone density distribution was adapted to implant a cementless stem. (
  • Conversely, a cement thickening rigidifies the cemented implant, consequently increasing interfacial stresses and micromotions. (
  • 1] J. Jansen, E. Ooms, N. Verdonschot, J. Wolke, Injectable calcium phosphate cement for bone repair and implant fixation, Orthop Clin North Am 36 (2005) 89-95. (
  • A common technique to aid in implant fixation into surrounding bone is to inject bone cement into the space between the implant and surrounding bone. (
  • In addition, PMMA by itself is not visible using typical medical imaging techniques (such as X-rays required to assess new bone formation surrounding the implant). (
  • There were 62 such cases involving bone cement for this procedure reported during this time period, when up to 200,000 patients would have been treated with a hip implant to treat their hip fractures. (
  • Cemented THA has been found to be durable and the cemented femoral component has proven to be the best performing implant in many cases [ 2 - 4 ]. (
  • Hip implant operations which involved the use of bone cement has resulted in the deaths of more than 40 patients in the U.K. According to researchers at the National Health Service (NHS), at least 62 patients have died or suffered adverse health complications following hip replacement surgery where bone cement was used. (
  • Experimental investigation of the effect of surface roughness on bone-cement-implant shear bond strength. (
  • The results indicated that both cements were osteoconductive, biocompatible and biodegradable but their different physicochemical and biological properties had a marked influence on their post-implant behaviour. (
  • Polymer based surgical bone cements have been used for many years to fill voids in bones and to improve fixation of implanted orthopaedic prosthetic devices. (
  • Bone cement is a material used for the fixation of joint implants to the bone. (
  • In addition, bone cement provides bone stability during internal fixation surgery. (
  • Moreover, bone cements provide stability to the bone during internal fixation surgery. (
  • Kirschner wires or K-wires are sterilized, sharpened, smooth stainless steel pins widely used to hold bone fragments together (pin fixation) or to provide an anchor for skeletal traction in fractures. (
  • AbstractThe usage of cemented fixation for total hip replacement still exists for older people and patients having voids and irregular femurs. (
  • Although promising, there are numerous disadvantages of using PMMA in bone fixation applications which has limited its wide spread use. (
  • In a study of 25,000 patients on the National Joint Registry in Australia, statisticians similarly reported that although cemented fixation carried an increased risk of death within one day of surgery, it resulted in a reduced risk of mortality at all time periods thereafter: one week, one month and one year. (
  • An obvious means to improve the fixation of a cancellous bone screw is to augment the surrounding bone with cement. (
  • Previous studies have shown that bone augmentation with Calcium Phosphate (CaP) cement significantly improves screw fixation. (
  • The present study aims to show the effect of cement distribution on the screw fixation strength for various cortical thicknesses and to determine the conditions at which cement augmentation can compensate for the absence of cortical fixation in osteoporotic bone. (
  • These bone constructs were used to test the fixation strength of cancellous bone screws in different cortical thicknesses and different cement augmentation depths. (
  • Indeed, cement augmentation without cortical fixation increased pullout forces over that of screws without cement augmentation but with cortical fixation. (
  • Since cement augmentation significantly increased pullout force in all cases, we conclude that the loss of cortical fixation can be compensated by cement augmentation. (
  • The bone cement fills the free space between the prosthesis and the bone and plays the important role of an elastic zone. (
  • The cause of the low polymerization temperature in the body is the relatively thin cement coating, which should not exceed 5 mm, and the temperature dissipation via the large prosthesis surface and the flow of blood. (
  • Bone cement plugs the gap between bone and prosthesis. (
  • Healthcare giants such as Exactech, Inc. have received USFDA approval for Optetrak Logic Constrained Condylar (CC) Prosthesis to treat the bones. (
  • Bone Cement is being used for in arthroplasty procedures for over four decades for the purpose of total joint replacement prosthesis to periprosthetic bone. (
  • The bone cement may be prepackaged in a syringe, or may be molded for use in connection with a particular prosthesis, or may be packaged unitarily with a prosthesis. (
  • In these procedures, the prosthesis is typically cemented in place by use of a polymethylmethacrylate bone cement. (
  • Keaveny, T. and Bartel, D. (1993) Mechanical consequences of bone ingrowth in a hip prosthesis inserted without cement. (
  • Revision operation (thorough debridement + removal of the prosthesis + antibiotic bone-cement implanting + local or systematical application of antibiotics + joint replacement) is the golden rule of treating joint infection. (
  • After hospitalized, patient's erythrocyte sedimentation was 125 mm/h and C reactive protein 171.49 mg/L. Joint puncture, bacterial culture and drug-sensitivity test were performed before the surgery, and on Mach 29, 2015, focal debridement of the infected joint + removal of the prosthesis + antibiotic bone cement implanting + focal tube insertion occludes perfusion washing. (
  • Bone casting is useful in a variety of orthopedic applications including hip arthroplasty, wrist joint arthroplasty and others, for example, calcium phosphate-based materials are now widely used. (
  • The polymethyl methacrylate (PMMA) cement segment is expected to dominate the market in 2025 owing to extensive use of PMMA in various orthopedic procedures such as arthroplasty, kyphoplasty, and verteboplasty. (
  • The bone cement market by application was segmented into broplasty, arthroplasty, and kyphoplasty. (
  • BACKGROUND: Although shoulder arthroplasty is an accepted treatment for osteoarthritis, loosening of the glenoid component, which mainly occurs at the bone-cement interface, remains a major concern. (
  • During cemented hip arthroplasty, bone cement may contaminate the bearing surface. (
  • Surgeons should be aware of this potentially serious effect on the bearing and be vigilant to avoid bone cement contamination during arthroplasty surgery. (
  • Since Sir John Charnley first used bone cement in conjunction with the Low Friction Arthroplasty in 1962, poly methyl methacrylate (PMMA) bone cement and polyethylene has been used extensively in total hip arthroplasty (THA) [ 1 ]. (
  • Bone cement complications were first reported back in 2009, but it continues to be used during hip arthroplasty surgery, often in elderly patients with heart problems. (
  • Bone cement implantation syndrome is a toxic reaction that occurs in patients who undergo hip arthroplasty surgery with bone cement. (
  • Many studies demonstrate the antibacterial effectiveness of antibiotic-loaded bone cement for the treatment of deep infections following hip and knee arthroplasty. (
  • Post-operative management of local infection after unicompartmental knee arthroplasty with antibiotic bone cement implanting: Nursing. (
  • Bone Cement Market report is an overview of the Global Bone Cement Industry It covers all the recent trends including key developments in the global Bone Cement market in present analysis and future predictions of the global Bone Cement market trends along with the projections provided in the research report. (
  • Global Bone Cement Market Report provides main statistics connected to the overall market and value forecast over a period, from 2019 to 2028. (
  • According to a new market research study titled 'Bone Cement Market to 2025 - Global Analysis and Forecasts by Type, Application and End User, the global bone cement market was valued at US$ 927.3 Mn in 2017 and is estimated to reach US$ 1414.1 Mn by 2025. (
  • The report highlights the trends prevalent in the global bone cement market and the factors driving the market along with those that act as deterrents to its growth. (
  • The global bone cement market is a mature market in the developing countries as well as in developing economies worldwide. (
  • The global bone cement market by type was led by polymethyl methacrylate (PMMA) cement segment. (
  • To analyze and forecast the global Bone Cement market on the basis of type, application, and end user. (
  • The key findings and recommendations highlight crucial progressive industry trends in the global Bone Cement market, thereby allowing players across the value chain to develop effective long-term strategies. (
  • Key players in bone cement and casting materials market are Smith & Nephew plc, Zimmer Biomet Holdings, Exactech, BSN medical GmbH, 3M Health Care Ltd, Stryker Corporation, Orthofix International, and DePuy Orthopaedics. (
  • GlobalData's new report, 'China Orthopedic Bone Cement and Casting Materials Market Outlook to 2020', provides key market data on the China Orthopedic Bone Cement and Casting Materials market. (
  • The report also provides company shares and distribution shares data for each of these market categories, and global corporate-level profiles of the key market participants, pipeline products, and news and deals related to the Orthopedic Bone Cement and Casting Materials market wherever available. (
  • Market size for Orthopedic Bone Cement and Casting Materials market categories -Bone Cement and Casting Materials. (
  • Global corporate-level profiles of key companies operating within the China Orthopedic Bone Cement and Casting Materials market. (
  • adds report "Mexico Orthopedic Bone Cement and Casting Materials Market Outlook to 2020" to its store. (
  • This report provides key market data on the Mexico Orthopedic Bone Cement and Casting Materials market. (
  • Orthopedic Bone Cement Market Size Worth $1.1 Billion by 2025: Grand View Research, Inc. (
  • Orthopedic bone cement helps support and anchor artificial joints and fractured bones. (
  • The motive of this strategic research report entitled "Global Orthopedic Bone Cement and Casting Materials Market 2017″ is to provide company officials, industry investors, and industry members with consequential insights to enable them make reliable strategic decisions regarding the opportunities in the global Orthopedic Bone Cement and Casting Materials market. (
  • Global Orthopedic Bone Cement and Casting Materials Market 2017 "offers crucial insights into the global Orthopedic Bone Cement and Casting Materials market along with the market size and estimates for the duration 2017 to 2023. (
  • Most of the Key Players Functioning in the Orthopedic Bone Cement and Casting Materials Market follow the strategy of operational extension in order to boost the production capacity, market existence, client base. (
  • This Report scrutinize the global Orthopedic Bone Cement and Casting Materials market in terms of product type, applicaion service, client, and geography.The global Orthopedic Bone Cement and Casting Materials market covers major continents. (
  • The global Orthopedic Bone Cement and Casting Materials market gets segmentized into two parts product and application. (
  • The Report serves as a valuable guide for the industry players and other individuals who are interested in studying the Orthopedic Bone Cement and Casting Materials market. (
  • The set time can be tailored to help the physician safely apply the bone cement into the bone bed to either anchor metal or plastic prosthetic device to bone or used alone in the spine to treat osteoporotic compression fractures. (
  • You have invented a new elastic bone cement for spinal fractures. (
  • Increasing adoption of bone glue due to its innovative and advanced applications in the management of fractures is the main factor contributing to the high growth rate of this segment. (
  • Therefore, cements with a lower stiffness are desired in order to potentially decrease the risk of additional fractures, and such cements have been the object of investigation by different research groups. (
  • In 2000, spinal surgeons had few options if they wanted to use a cement-type product to treat vertebral-compression fractures to reduce pain. (
  • The company says that the cement is ideal "for the treatment of complex osteoporotic and oncologic fractures. (
  • Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. (
  • This study is a multi-center, non-randomized prospective case series of tibial plateau fractures using Norian Drillable to fill bone voids, to evaluate OR time, blood loss, complications, ease of use, fracture stabilization and patient function and pain over time. (
  • Norian tested the cement from 2002 to 2004 on 200 patients, though the bonding agent explicitly stated it was "not intended for treatment of vertebral compression fractures. (
  • In the 2013 'Guidance on the management of hip fractures in adults', NICE recommended the use of cement due to both improve clinical outcomes and reduced mortality at 30 days . (
  • During balloon kyphoplasty, bone cement (often a pasty compound called PMMA) is injected into the cavity created with the balloon tamp inside the fractured vertebral body. (
  • Where the target bone site is a porous cancellous structure, e.g., as may be encountered in a reduced fracture or inside a compromised vertebral body, one approach is to deliver the cement under high pressure, so that it adequately penetrates the cancellous bone tissue. (
  • PMMA cement were injected into vertebral body in rabbits via mimic PVP, sacrificed at 1 h, 24 h, 3 d, 7 d, 4 w, and 12 w. (
  • To prevent complication caused by leakage of bone cement injected into the vertebral body, organism damage caused by the leakage of the monomer or a non-cured component from bone cement and decrease of strength caused by insufficient curing of bone cement, in the percutaneous kyphoplasty, a leakage prevention. (
  • In this study, we investigated whether the distribution of the cement in the vertebral body is related to the occurrence of recompression after surgery. (
  • Patients with bone cement distributed around both upper and lower endplates had a significantly less incidence of recompression (4/50 patients), when compared to other patterns of cement distribution (eg, below upper endplate, above lower endplate, and in the middle of vertebral body). (
  • The logistic multiple regression analysis also indicated that patients with bone cement distributed around both the upper and lower endplates had a lower risk of recompression when compared to patients with bone cement distributed in the middle of vertebral body (odds ratio =0.223, P =0.003). (
  • Extravasated methyl methacrylate in the venous system is a common finding after vertebral augmentation procedures and any radiopaque stripe arising from a cemented vertebral body should be first described as probable cement leakage. (
  • Abstract: This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate chitosan block bone and chitosan membrane on the regeneration of 1- wall intrabony defects in the beagle dogs. (
  • Abstract: Manganese is one of metallic elements which appear in biological apatite like bone and teeth. (
  • Our market leading Hydroxyapatite bone cements for cranial applications provide you with flexible delivery systems to assist with OR efficiency and patient outcomes. (
  • Composed of pure biphasic calcium sulfate & hydroxyapatite and characterized by a predetermined setting time and resorption rate, 4MATRIX is the preferred augmentation product for a wide variety of dental bone grafting procedures. (
  • The formulated hydroxyapatite component contributes to the longer term space maintaining properties and provides higher mechanical strength and stabilization of the graft for newly regenerated bone. (
  • The cement mixes together with a mineral called hydroxyapatite, which is found naturally in bones and teeth. (
  • Based on the materials used, the bone cement market is classified as polymethylmethacrylate (PMMA), acrylate-based plastics, ceramics, calcium sulfate, calcium phosphate and corraline hydroxyapatite cement. (
  • also modified their cements with strontium-substituted hydroxyapatite-nanoparticles and linoleic acid and reported similar compressive strengths accompanied by a reduction of 63.9% in Young's modulus when 20 wt% nanoparticles with 15 vol% linoleic acid were incorporated [ 15 ]. (
  • On the basis of material used, the bone cements market is segmented into polymethyl methacrylate (PMMA), acrylate based plastics, ceramics, calcium sulfate, calcium phosphate and coralline hydroxyapatite cements. (
  • In this study we investigated a composite prepared from a hydroxyapatite forming bone cement and mesoporous bioactive glass (MBG) granules as a potential carrier for biologically active proteins. (
  • The presence of this magnesium in the hydroxyapatite layer could improve the adhesion of the bone cement to living bone. (
  • Lastly, although PMMA does support new bone growth, studies have highlighted decreased osteoblast (bone forming cell) functions on PMMA compared to other common orthopedic coating materials, such as calcium phosphates and hydroxyapatite. (
  • An orthopaedic bone cement mixing device comprising a mixing bowl (1) and a lid (3), said lid (3) having a handle (4) extending outwardly therefrom. (
  • It is by far the most common choice of bone cement due to its workability and is widely used in orthopaedic theatres (Wang & Dunne 2008). (
  • The fatigue life for orthopaedic bone cement is to be determined up to 5 million (5 × 10 6 ) cycles. (
  • This fatigue test method is not intended to represent the clinical use of orthopaedic bone cement, but rather to characterize the material using standard and well-established methods. (
  • Antibiotic-loaded bone cement was developed in view of the infections occurring in the orthopaedic surgery. (
  • After a thorough inspection of the global orthopaedic bone cement and casting materials market, the analysts have noticed that bone cement and casting materials manufacturing companies are more focussed towards minimizing the pricing and demand for orthopaedic treatment. (
  • This report covers the global orthopaedic bone cement and casting materials market performance in terms of revenue contribution from various segments. (
  • This section also includes Future Market Insights' analysis of key trends, drivers, restraints and opportunities, which are influencing the growth of the global orthopaedic bone cement and casting materials market. (
  • The primary objective of the report is to offer updates and information related to market opportunities in the global orthopaedic bone cement and casting materials market. (
  • The key part of this report is Future Market Insights' analysis and recommendations on the global orthopaedic bone cement and casting materials market. (
  • The report takes an overview of the global orthopaedic bone cement and casting materials market. (
  • The overview mainly consists of market taxonomy and market dynamics that underlines factors influencing the growth of the global orthopaedic bone cement and casting materials market. (
  • The general market scenario is assumed for orthopaedic bone cement and casting materials sales and driving factors are assumed to develop the market forecast. (
  • The report covers the competitive landscape that provides a dashboard view of companies that manufacture and provide services in the global orthopaedic bone cement and casting materials market. (
  • The data that is provided in the global orthopaedic bone cement and casting materials market is validated using the triangulation method, wherein secondary and primary data and Future Market Insights' analysis contribute to the final data. (
  • Clinical orthopaedic use of calcium phosphate cement has been limited due to its slow resorption rate, but a new macroporous a-tricalcium phosphate (a-TCP) bone cement has been designed to accelerate resorption and to increase bone ingrowth. (
  • Right ventricular perforation and pulmonary embolism with polymethylmethacrylate cement after percutaneous kyphoplasty. (
  • Zarate B, Gutierrez J, Wakhloo AK, Gounis MJ, Reyes-Sánchez A. Clinical evaluation of a new kyphoplasty technique with directed cement flow. (
  • The excellent tissue compatibility of PMMA allowed bone cements to be used for anchorage of head prostheses in the 1950s. (
  • However, a disadvantage of high-pressure delivery methods is that they can result in penetration beyond the site of interest, and delivery may be hard to control, such that even when the pressure source is removed, cement still penetrates the tissue, perhaps to undesirable areas and/or causing undesirable side effects. (
  • Such a bone cement formulation decreases the exothermic temperature of the bone cement and decreases the possibility of tissue necrosis in the implantation area. (
  • The resulting apatite - a fundamental building block of bone tissue - then closes the crack again. (
  • The technology provides a method for making scaffolds for bone tissue that is seeded with a patient's own cells and formed with a cement paste made of bone minerals. (
  • Described in recent and upcoming journal articles,* the new technology provides a method for making scaffolds for bone tissue. (
  • Osteoporosis is a medical condition, characterized by low bone density along with deterioration of bone tissue. (
  • However, they lack sufficient porosity to allow immediate bone ingrowth and thus foster rapid integration into the bone tissue. (
  • These materials have potential application in fabricating 3D scaffolds for bone tissue engineering and regenerative medicine, or as medical devices. (
  • The remodelling rate equation is obtained from the structural optimization task of maximizing the stiffness subject to a biological cost associated with metabolic maintenance of bone tissue in time. (
  • The conversion of this bioactive glass into calcium phosphate products could also attract surrounding bone growth, further integrating implants with tissue and removing space on the cement surfaces where biofilms can form. (
  • Jansen, PLGA microsphere/calcium phosphate cement composites for tissue engineering: in vitro release and degradation characteristics, J Biomater Sci Polym Ed 19 (2008) 1171-1188. (
  • The biomaterials can be applied to bone reparation and bone tissue engineering scaffolds The nano-pore structure, degradability, bioactivity and bio-mineralization characteristic of the biomaterials were investigated in details using XRD, SEM/EDX, FTIR, BET and DSC/TG techniques. (
  • Specifically, the PMMA polymerization reaction is highly exothermic in situ, thus, damaging surrounding bone tissue while curing. (
  • Comprehensive clinical tests of the compatibility of bone cements with the body were conducted before their use in surgery. (
  • Bone cement is considered a reliable anchorage material with its ease of use in clinical practice and particularly because of its proven long survival rate with cemented-in prostheses. (
  • Calcium phosphate bone cements (CPCs) with antibacterial properties are demanded for clinical applications. (
  • This book presents comparative clinical and preclinical studies in classical and modern bone cements focusing on properties, techniques, antibiotic-loaded cements, and osteolysis. (
  • Synthes and Norian, along with four top executives, were indicted in 2009 on charges of conducting unauthorized clinical trials despite warnings that the bone cement caused deadly blood clots. (
  • Wyss directed a few sites to perform 60 to 80 procedures in spinal surgeries using the Norian bone cement and to publish clinical results. (
  • PURPOSE: To describe the technique and clinical outcome of percutaneous injection of bone cement in the treatment of symptomatic para-articular intraosseous cysts. (
  • However, factors such as porosity, viscosity, radiopacifiers, sterilization, biocompatibility and presence of antibiotic additives and mixing methods are known to affect the clinical performance of bone cements. (
  • The evidence that the safe use of bone cement confers clinical advantage for the outcome of hip surgery after fracture of the hip is overwhelming. (
  • The National Institute for Health and Care Excellence (NICE) recommends the use of cement due to both improved clinical outcomes and reduced mortality at 30 days. (
  • There is strong evidence that the safe use of bone cement confers clinical advantages compared to surgery that does not use bone cement. (
  • Unsaturated fatty acids and their glycerol esters are both natural compounds that can be used to modify the properties of bone cements. (
  • The bone cement viscosity changes over time from a runny liquid into a dough like state that can be safely applied and then finally hardens into solid hardened material. (
  • While the individual components are not always perfectly safe as pharmaceutical additives and active substances per se, as bone cement the individual substances are either converted or fully enclosed in the cement matrix during the polymerization phase from the increase in viscosity to curing. (
  • San Jose, California -- Vertebral treatment technology company DFINE has announced the launch of the latest addition to its family of ultra-high viscosity bone cements. (
  • Called StabiliT ERx, the next generation semantic has five times greater viscosity than other PMMA bone cements. (
  • Ryan focuses on cases involving high-viscosity bone cements and cases involving defective dietary supplements. (
  • He primarily focuses on cases involving high-viscosity bone cements , which are causing early revision surgeries due to mechanical loosening. (
  • There are three types of bone cement: low, medium, or high-viscosity cement (HVC). (
  • The results indicated that the static shear strength was more dependent on cement type than cement viscosity and volume. (
  • However, both cement type and viscosity were contributory factors on porosity and micropore size in the cement surface. (
  • This study aimed to investigate the processing parameters and biocompatibility of a novel biphasic dicalcium silicate (C 2 S) cement. (
  • In vitro bioactivity and biocompatibility studies were assessed by soaking the cement samples in simulated body fluid (SBF) and human adipose stem cell cultures. (
  • However, there is no data available on the in vivo biocompatibility of any low-modulus cement. (
  • In summary, we conclude that injectable CPC-dense PLGA composites proved to be the most suitable material for a potential use as off the shelf material due to its good biocompatibility, enhanced degradability and subsequent bone formation. (
  • In vitro biocompatibility of cements on human osteoblasts is ensured. (
  • An ideal antibiotic-loaded bone cement must not affect the normal bone graft characteristics of biocompatibility, bioresorbability, osteoconductivity, osteoinductivity, structural similarity, easy to use, and cost-effectiveness. (
  • This study reports on the incorporation of the self-setting polysaccharide derivative hydrogel (silanized-hydroxypropyl methylcellulose, Si-HPMC) into the formulation of calcium phosphate cements (CPCs) to develop a novel injectable material for bone substitution. (
  • Calcium phosphate cements (CPCs) are the predominant type of bone substitute material used for reasons of injectability and hence perfect filling potential for bone defects. (
  • In this study, the performance of injectable CPCs as a bone substitute material for alveolar bone defects created in Beagle dogs was evaluated. (
  • The bone glue segment is expected to grow at the fastest rate during the forecast period. (
  • The increasing number of hospital in-patient-based orthopedic procedures is driving the demand for bone cement and glue in this segment. (
  • In 2017, the polymethyl methacrylate (PMMA) cement segment held a largest market share of 47.1% of the bone cement market, by type. (
  • Advanced composition, simplicity and ease of use: These terms best describe the new 4MATRIX Bone Graft solution delivered by MIS Implants Technologies Ltd. (
  • This all-in-one innovative product was developed to simplify dental bone grafting procedures for dental prosthetic solutions and implants. (
  • This intrinsic self-healing ability - and the greater load-bearing capacity associated with fibre reinforcement - could considerably expand the areas in which bone implants made of calcium phosphate cement can be used, which could possibly also include load-bearing areas of the skeleton in the future. (
  • Description: ISO 21534:2007 specifies particular requirements for total and partial joint replacement implants, artificial ligaments and bone cement , referred to as implants in the text. (
  • U.S. scientists say they've developed a technology for implants that might improve construction or repair of facial, skull and jaw bones. (
  • A new technology for implants that may improve construction or repair of bones in the face, skull and jaw, has been developed by researchers from the American Dental Association Foundation (ADAF) and the National Institute of Standards and Technology (NIST). (
  • For example, prosthetic knee implants can come in either cemented or cementless form. (
  • During cementation and pressurization of the femoral stem and/or acetabular component, it is possible that bone cement could extrude around the implants and contaminate the bearing surface of the acetabular liner/component. (
  • Debonding of cemented bone implants is regarded as a major contributor to complications. (
  • More particularly, the present invention is directed to improved polymethylmethacrylate bone cements for securing metal and plastic prostheses to bone and to the methods of preparing such bone cements. (
  • A team from the University of Limerick in 2017 developed a new type of cement, which reduces the time needed for orthopedic operations and helps broken bones to heal and conjoin more quickly. (
  • 6. The method according to claim 1 , wherein said target bone site comprises a fracture. (
  • However, doctors often have to lend a helping hand to repair bones after a fracture or due to a defect. (
  • It exhibited a much lower bending strength and bending modulus compared with the other three bone cements (CMW1, CMW2000 and Simplex P). The textures of tensile fracture surfaces produced were similar for the four bone cements studied. (
  • It appears that the agglomerates of zirconium dioxide particles are implicated in Palacos R-40 bone cement fracture surface. (
  • This leads to connective tissues such as ligaments attached to the bones becoming less flexible and more constrained which results in early bone loss and increased risk of fracture. (
  • There have been recent media reports regarding use of bone cement in hip replacement surgery following a hip fracture. (
  • The BMJ Open article is based on a study that has looked at risk of death or severe harm associated with partial hip replacements for people with a fracture at the top of the thigh bone (fractured neck of femur) where bone cement has been used in the surgical procedure. (
  • The BMJ Open article suggests an increased mortality with cement use of 1 in 2900 procedures, an increased risk of mortality of 0.03%, yet the mortality associated with a hip fracture is 8.6% at 30 days, suggesting there are other major factors which influence survival. (
  • Asia Pacific is expected to have the fastest growth rate due to improving healthcare infrastructure, heavy burden of orthopedic medical conditions, rising awareness about management of orthopedic diseases, and growth in the demand for bone cement and glue. (
  • Ageing population is another important factor responsible for increasing demand for bone cement. (
  • Furthermore, rise in umber of osteoporosis cases and increase in number of bone disease cases are expected to boost the demand for bone cement in the coming years. (
  • 2020) Self-healing capacity of fiber-reinforced calcium phosphate cements. (
  • Particles of 13-93B3 with diameters of 5 μm, 33 μm, and 100 μm were mixed into a PMMA-based commercial bone cement, DePuy SmartSet MV, to create composites with 20%, 30%, and 40% glass loadings. (
  • The composites were formed into pellets and paired with bone cement control groups. (
  • Results from these tests suggest that composites made of 13-93B3 and bone cement may have a promising future in helping to prevent periprosthetic infections and would benefit from further investigation. (
  • Jansen, Effect of polymer molecular weight on the bone biological activity of biodegradable polymer/calcium phosphate cement composites. (
  • Properties of nanofiller-loaded poly (methyl methacrylate) bone cement composites for orthopedic applications: a review. (
  • The chemical composition, microstructure, and mechanical properties of the raw materials and resulting calcium phosphate cements and composites have been characterized by X-ray Diffraction (XRD), scanning electron microscope (SEM), electron energy dispersive spectrometer (EDS), and Instron universal mechanical testing machine. (
  • 4MATRIX's unique and novel engineering process produces a composite graft material with rapid bone regeneration and optimal space maintaining properties. (
  • To facilitate these operations, bone substitute companies are engaged in a constant search for the ultimate matrix that can bond their products, for preventing particle migration and obtaining the stability of the bone graft. (
  • The evolution of dental bone graft cement simplifying and enhancing our augmentation abilities, while paving the future of the maxillofacial and dental augmentation field. (
  • Rationale for bone grafting procedures and graft selection. (
  • Use of cement bone grafts in the orthopedic medical field is state of the art , and have existed for years. (
  • However, in the dental field, the use of bone grafts cements is relatively unfamiliar. (
  • What is referred to as bone cement implantation syndrome (BCIS) is described in the literature. (
  • Bone cement lawsuits are being filed for the development of the life-threatening reaction called Bone Cement Implantation Syndrome (BCIS) and in certain cases when the bone cement failed and required the patient to undergo revision surgery. (
  • In addition, some unfortunate patients have suffered from Bone Cement Implantation Syndrome, which causes a deadly reaction during or shortly after cementation, causing side effects like hypoxia and pulmonary embolism, among other life-threatening reactions. (
  • The two main complications from bone cement failure are implantation syndrome and aseptic loosening. (
  • Known as Bone Cement Implantation Syndrome (BCIS) , it is a serious and life-threatening condition. (
  • There is speculation that these toxins and particles can make their way into surrounding tissues, veins, nerves at the implantation site from the needle used during surgery to apply the cement. (
  • The BMJ Open article is "What is the risk of death or severe harm due to bone cement implantation syndrome among patients undergoing hip hemiarthroplasy for fractured neck of femur? (
  • It is known that in a small proportion of cases the use of bone cement can lead to 'bone cement implantation syndrome' (BCIS) at or around the time of the operation, and surgeons and anaesthetists are aware of the techniques they need to use to reduce the risk of this occurrence. (
  • Hip surgery patients who are treated with bone cement can potentially develop a rare but life-threatening side effect known as Bone Cement Implantation Syndrome . (
  • Bone Cement Implantation Syndrome (BCIS) is a rare and poorly-understood syndrome that occurs when bones spontaneously release fat and marrow into the bloodstream after bone cement is injected. (
  • No inflammatory reaction was detected at any time period following implantation with either macroporous or standard cement. (
  • Copal is a new antibiotic-loaded bone cement especially designed for revision cases. (
  • Albany, US, 2019-Sep-20 - /EPR Network / -Infections are among the major issues encountered during various orthopedic surgeries, and antibiotic-loaded bone cement is commonly used to avoid any sorts of medical predicaments. (
  • To ensure the safety of patients undergoing orthopedic surgeries, the demand for antibiotic-loaded bone cement is increasing across the healthcare industry. (
  • The antibiotic-loaded bone cement market is gaining momentum with the growing awareness about the therapeutic effects of antibiotic-loaded bone cement during various orthopedic surgeries. (
  • Growing applications of antibiotic-loaded bone cement in most orthopedic surgeries, especially for treating hip and knee joint infection, is likely to boost the growth of the antibiotic-loaded bone cement market in the upcoming years. (
  • Antibiotic-loaded Bone Cement is the pre-fabricated cement which passes certain regulations and is approved by FDA. (
  • The antibiotic selection is also a fundamental issue for the preparation of antibiotic-loaded bone cement. (
  • The most regularly used antibiotics in the development of antibiotic-loaded bone cement include gentamycin, tobramycin and vancomycin. (
  • The effectiveness of antibiotic-loaded bone cement is hugely dependent on the choice of antibiotics and their proper mixing of antibiotics with the cement. (
  • Though the effectiveness of antibiotic-loaded bone cement has contributed greatly to the growth of the antibiotic-loaded bone cement market, its economic benefits have been doubted by end-users. (
  • Thereby, offering cost-effective and economic benefits of antibiotic-loaded bone cement remains the primary priority for stakeholders in the antibiotic-loaded bone cement market. (
  • Manufacturers in the antibiotic-loaded bone cement market are investing heavily in providing more effective products to deal with various problems occurred during orthopedic surgeries such as antibiotic resistance and bacterial adhesion. (
  • This marks an emerging trend among leading manufacturers, distributors, and other stakeholders in the antibiotic-loaded bone cement market. (
  • Growth in the development of synthetic materials and their acceptance fuels the market growth of antibiotic-loaded bone cement. (
  • Various key developments such as product advancements and launches, mergers and acquisitions by the market players in the orthobiologics market also drive the market growth in antibiotic-loaded bone cement market. (
  • However, stringent regulations may obstruct the growth of antibiotic-loaded bone cement market. (
  • Along with this, a recent publication by the FDA questioned about the role of antibiotic-loaded bone cement spacers for the treatment of periprosthetic joint infection which may further hamper the market growth. (
  • METHODS: Finite element analysis of a prosthetic scapula was used to evaluate the effect of cement thickness on stresses and micromotions at the bone-cement interface. (
  • The global bone glue market is segmented by type, application, end user, and region. (
  • By type, the market is segmented into bone cement and bone glue. (
  • By end user, the bone cement and glue market is segmented into hospitals, clinics/physician offices, and ambulatory surgery centers. (
  • THURSDAY, Jan. 11, 2018 (HealthDay News) -- Injecting a calcium -based cement into the bones of some people with knee or hip pain could help them avoid joint replacement surgery, Ohio State University doctors say. (
  • On 3 January 2018, the company said it began selling the PALACOS portfolio of bone cement products direct through its affiliate Heraeus Medical LLC in the US. (
  • The report then estimates 2018-2023 market development trends of Bone cement industry. (
  • The global Bone Cement & Glue market will reach Volume Million USD in 2018 with CAGR xx% 2018-2025. (
  • The Insight Partners added Bone Cement Market Report 2018-2025 to its research database. (
  • EMAILWIRE.COM , December 08, 2018 ) The bone cement market is estimated to grow at a CAGR of 5.4% during the forecast period from 2018 to 2025. (
  • Increasing incidents of falls, road-accidents, and sports injuries is expected to foster growth of antibiotic bone cement and casting materials market. (
  • Rising number of road accidents is thus expected to boost growth of the antibiotic bone cement and casting materials market over the forecast. (
  • High cost of joint replacement surgeries is a factor expected to restrain antibiotic bone cement and casting materials market growth. (
  • On the basis of region, antibiotic bone cement and casting materials market by Coherent Market Insights is segmented in to North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. (
  • A comprehensive analysis of the factors limiting and regulating the growth of the global bone cement and casting materials market is provided. (
  • This translates into the competitive prospects of the global bone cement and casting materials market. (
  • 2014 company shares and distribution shares data for Bone Cement and Casting Materials market. (
  • Geographically, the bone cement and casting materials market is analyzed based on various regions such as North America, Europe, Asia-Pacific, and LAMEA. (
  • Comprehensive analysis of factors that drive and restrict the growth of the global bone cement and casting materials market is provided. (
  • Key players are profiled in this report and their strategies are analyzed thoroughly, which interprets the competitive outlook of the global bone cement and casting materials market. (
  • If you inject this substance into the bone, you're basically providing internal support, a scaffold protecting the bone. (
  • The natural polymer beads gradually dissolve when exposed to the body's fluids, creating a scaffold that is filled by the now released bone cells. (
  • Our material is designed to be similar to mineral in bone so that cells readily attach to the scaffold. (
  • The scaffold is seeded with a patient's own cells and is formed with a cement paste made of minerals also found in natural bone. (
  • We compared the release of gentamicin from 6 different commercially available, antibiotic-loaded PMMA bone cements used for vacuum- and hand-mixed cement using a Cemvac vacuum mixing system. (
  • In conclusion, the manual addition and mixing of gentamicin in PMMA bone cements leads to a lower release of antibiotics than that in corresponding commercially available antibiotic-loaded cements, while vacuum-mixing only leads to a minor reduction in antibiotic release, as compared to hand-mixing. (
  • While the in vitro cytotoxicity appeared somewhat affected by the castor oil and linoleic acid additions, no difference could be found in the in vivo response to these cements in comparison to the base, commercially available cement, in terms of histology and flow cytometry analysis of the presence of immune cells. (
  • However, none of these cements are commercially available. (
  • However, shear strength at this interface has rarely been compared across a range of commercially available bone cements. (
  • This report studies sales (consumption) of Bone Cement market, focuses on the top players, with sales, price, revenue and market share with volume and value for each region. (
  • This in turn is expected to bolster the patient pool for joint replacement surgeries and in turn propel revenue growth for bone cement market over the forecast period. (
  • The Midwest with sales (volume), revenue (value), market share and growth rate of Bone Cement in these regions, from 2012 to 2022 (forecast). (
  • This commercial study encompasses detailed investigation of production, supply, sales, demand, price, cost, income and revenue on United States Bone Cement Gun Industry in Major Regions. (
  • The mechanical properties of the composite were not compromised by up to 10 wt% MBG granule addition, which can be attributed to the strong interface between the cement matrix and MBG particles, however this modification induced a significant increase in porosity within 3 weeks ageing in an aqueous liquid. (
  • We recently developed a new biomimetic calcium phosphate bone cement enriched with gelatin (GEL-CP) which exhibits improved mechanical properties with respect to the control cement (C-CP) and a good response to osteoblast-like cells. (
  • However, the huge difference between the mechanical properties of the cortical bone and bone cement led to inhomogeneous stress transfer in the stem/cement interface. (
  • its mechanical properties can potentially be altered by this thermal effect during cement polymerization [ 8 ]. (
  • The addition of antibiotics may play a role in weakening the structure and the mechanical properties of the cement. (
  • The porosity of cements was reduced in all vacuum-mixed cements, as compared with hand-mixed cements, concurrent with a statistically significant reduction (3 of 6) or increase (1 of 6) in the total amounts of gentamicin released. (
  • Although the bone cements were all hand mixed in this study, the static shear strength was significantly larger than the values recorded by other researchers, and the porosity and micropore size showed much lower values. (
  • The experts from Jena, who collaborated with colleagues from the University of Würzburg as part of the German Research Foundation's priority research programme 'Self-healing Materials', concentrated on what is called calcium phosphate cement - a bone substitute that is already widely used in medicine. (
  • Bone cement was introduced in 1940s and has been widely used by physicians since then. (
  • Bone casting is helpful in various orthopedic applications, which include hip replacement, wrist joint replacement, and others, for instance, calcium phosphate-based materials are widely used at present. (
  • Calcium phosphate (CaP) bone cements are widely used for the treatment of bone defects and have been proposed to serve as a delivery platform for therapeutic drugs, proteins and growth factors into the defect region. (
  • Calcium phosphates bone cements are widely used for bone-replacement materials due to their chemical similarity to natural bone but also their ability to set and harden in situ and their ability to be injected as a paste. (
  • During the augmentation procedure, the biphasic calcium sulfate component of 4MATRIX remains intact in the presence of blood and saliva and stimulates bone growth when placed in contact with bone or periosteum. (
  • This course discusses the evolution of bone augmentation materials. (
  • Cement augmentation significantly increased pullout force in all cases. (
  • The effect of cortical thickness on pullout force was reduced with increased cement augmentation depth. (
  • Bone cement chemically is nothing more than Plexiglas (i.e. polymethyl methacrylate or PMMA). (
  • Osteoplasty involves injecting bone cement (here they used polymethyl-methacrylate or PMMA) into a bone lesion with the help of image guidance. (
  • While these results are promising, the mechanical behavior of these cements in vivo remains to be investigated. (
  • 5.2.1 Testing is conducted at three stress levels to characterize the general fatigue behavior of a cement over a range of stresses. (
  • It was found that Si-HPMC could endow composite CPC pastes with an appealing rheological behavior at the early stage of setting, promoting its application in open bone cavities. (
  • Ginebra, Of the in vivo behavior of calcium phosphate cements and glasses as bone substitutes, Acta Biomater. (
  • In this work, we have extended the investigation to primary culture of osteoblasts derived from normal (N-OB) and osteopenic (O-OB) sheep bones cultured on samples of GEL-CP, and their behavior was compared to that of cells cultured on C-CP as control. (
  • Synthes bought the California-based Norian Corporation, which had developed bone cements used in skull and arm-bone surgeries. (
  • A Synthes employee in its regulatory division warned company officials the FDA had said it couldn't use Norian bone cement in spinal surgeries without approval. (
  • In 2003, a patient died on a Texas operating table after a spinal surgeon injected Synthes bone cement into her vertebrae. (
  • By 2006, the FDA had cleared Synthes to market a bone cement called Norian CRS but said its label must state it's not to be used on the spine. (
  • West Chester medical-device manufacturer Synthes Inc. and its Norian Corp. subsidiary formally pleaded guilty Tuesday to charges that they illegally experimented with a bone cement on patients' spines and will pay fines totaling $23.2 million. (
  • A lawsuit was recently filed against Johnson & Johnson's Synthes unit and its former subsidiary Norian Corp. on behalf of the family of a woman who died during an unapproved bone cement trial. (
  • Treatment of symptomatic para-articular intraosseous cysts by percutaneous injection of bone cement. (
  • mean age 35 years) with painful para-articular intraosseous cysts were treated by percutaneous injection of bone cement under combined fluoroscopic and computed tomography (CT) guidance. (
  • CONCLUSIONS: Percutaneous injection of bone cement was a safe and efficient technique in the management of symptomatic para-articular intraosseous cysts in our population. (
  • The vast majority of patients with cement leakage and even cement pulmonary embolism remain asymptomatic. (
  • Medtronic Inc. has recalled all lots of Kyphon® bone cement devices because a misalignment issue could result in nerve damage, paralysis, pulmonary embolism, cardiac arrest, or death. (
  • Possible risks associated with this misalignment include cement extravasation into the spinal canal with a possible result of paralysis or nerve injury with a risk of pulmonary embolism or cardiac arrest. (
  • The invention relates to surgical bone cement compositions and more particularly to bone cement compositions having aneasthetic properties, and to methods for producing analgesia. (
  • Bone Cement': A Non-Surgical Option for Joints? (
  • But there's a very narrow window of patients who are good ideal candidates for this, who basically have a real overload of their bone causing severe enough pain to warrant a surgical procedure, but also have healthy enough cartilage that doing something about the bone swelling is going to alleviate the majority of their pain," he stressed. (
  • This can happen within a very short amount of time after the cement has been applied to the surgical site. (
  • The procedures in this test method may or may not apply to other surgical cement materials. (
  • Surgical procedures to reconstruct or repair bones have become extremely common. (
  • The surgical control group received a flap operation only, while experimental group was treated with calcium phosphate chitosan block bone and/or chitosan membrane. (
  • Injecting "bone cement" into lesions in patients whose cancer has spread to their bones can allow these individuals to live the remainder of their lives relatively pain-free. (
  • The diversity and complexity of bone lesions present challenges to clinicians, especially with existing bone substitutes marketed as granules, pastes, or blocks, which bring with them the need for stabilization by using membranes and fixating tools. (
  • In this study, artificial bone materials were used to mimic osteoporotic cancellous bone and cortical bone of varying thickness. (
  • Hence, the aim of this study was to investigate the effect of cement polymerization on a highly cross-linked polyethylene(HCLP) bearing surface as any process influences the surface roughness of the bearing surface can have potential long term effect on the wear rate. (
  • The composition of these types of cement is mostly based on calcium phosphate and more recently magnesium phosphate. (
  • Material scientists at the University of Jena have developed a bone replacement based on calcium phosphate cement and reinforced with carbon fibers. (
  • Note 2: In dentistry, polymer-based cements are also used as fillers of cavities. (
  • Bone cements consist of a powder (i.e., pre-polymerized PMMA and or PMMA or MMA co-polymer beads and or amorphous powder, radio-opacifier, initiator) and a liquid (MMA monomer, stabilizer, inhibitor). (
  • 7. The biocompatible bone replacement of claim 6 , wherein said liquid component includes a polymerizable compound, a polymerization accelerator, stabilizer, or mixtures thereof, wherein when said liquid component is mixed with said large particle constituent and said small particle constituent said polymerizable compound polymerizes to form a polymer structure. (
  • Poly(methyl methacrylate) (PMMA) is a synthetic thermosetting polymer that has been used as the base to produce bone cements for orthopedics since the 1960s, when Charnley first reported its use to anchor endoprostheses to bone [ 1 , 2 ]. (
  • The paste is mixed with beads of a natural polymer (made from seaweed) filled with bone cells. (
  • In addition to creating pores in the hardened cement, the natural polymer beads protect the cells during the 30 minutes required for the cement to harden. (
  • 6. Bone cement powder according to claim 1, further comprising at least one particulate polymethylmethacrylate or polymethylmethacrylate-co-polymer, a particulate radiopaquer, a radical initiator, and, optionally, a further antibiotic and/or antiseptic. (
  • Bone cements have been used very successfully to anchor artificial joints (hip joints, knee joints, shoulder and elbow joints) for more than half a century. (
  • Artificial joints (referred to as prostheses) are anchored with bone cement. (
  • Hip and knee registers for artificial joint replacements such as those in Sweden and Norway clearly demonstrate the advantages of cemented-in anchorage. (
  • Bone cement supports artificial joints of shoulder, knee, and elbow for more than half century. (
  • Upon activation of the 4MATRIX cement, the premixed powder is hydrated with sterile saline, ensuring complete wetting of the sterile mix, and a 3 minute working time. (
  • The system includes a mixing cartridge for receiving liquid and powder components of bone cement, a mixing device for mixing the components, and a delivery gun for discharging the bone cement from the mixing cartridge. (
  • said locking member including a resilient portion for biasing said at least one male portion into mating engagement with said at least one female portion in said cylinder wall whereby said piston remains in said locked position while mixing the liquid and powder components of the bone cement. (
  • 2. Bone cement powder according to claim 1, wherein the sugar alcohol comprises 4, 5 or 6 carbon atoms, whereby the sugar alcohol is selected from erythritol, xylitol, and mannitol. (
  • 3. Bone cement powder according to claim 1, wherein the weight ratio of sugar alcohol to calcium salt of fosfomycin is at least 1. (
  • 4. Bone cement powder according to claim 1, wherein the fosfomycin preparation is a solidified sugar alcohol melt with the calcium salt of fosfomycin dispersed in it. (
  • Antibiotics used for the preparation of bone cement is in the powder form for better integration with cement as well as lesser interference with the physical properties of the cement. (
  • The bone cement utilizes strontium salts as radiopacifiers, and comprises a powder component and a liquid component. (
  • Rick Friedman, the lawyer for Cindy Wilson, says the jury reached the decision on Friday that Dr. Jens Chapman did not act below the standard of medical care when he used the Norian bone cement on Reba Golden's back in 2007. (
  • The jury also found that Chapman failed to inform Golden about the risks associated with using Norian, but concluded that an informed person would have opted to use the cement anyway. (
  • The patients were never told Norian bone cement wasn't approved by the Food and Drug Administration. (
  • Norian Drillable Bone Void Filler is a moldable, biocompatible bone void filler with added reinforcing fibers. (
  • It may be possible to solve this problem by using incus interposition, autograft bone or cartilage or ossicular replacement prostheses. (