Body Burden: The total amount of a chemical, metal or radioactive substance present at any time after absorption in the body of man or animal.Environmental Pollutants: Substances or energies, for example heat or light, which when introduced into the air, water, or land threaten life or health of individuals or ECOSYSTEMS.Polychlorinated Biphenyls: Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants.Dioxins: Chlorinated hydrocarbons containing heteroatoms that are present as contaminants of herbicides. Dioxins are carcinogenic, teratogenic, and mutagenic. They have been banned from use by the FDA.Unithiol: A chelating agent used as an antidote to heavy metal poisoning.Food Contamination: The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage.Halogenated Diphenyl Ethers: Compounds that contain two halogenated benzene rings linked via an OXYGEN atom. Many polybrominated diphenyl ethers are used as FLAME RETARDANTS.Polybrominated Biphenyls: Biphenyl compounds which are extensively brominated. Many of these compounds are toxic environmental pollutants.Environmental Exposure: The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.Mercury: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.Lead: A soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.19, symbol Pb. (Dorland, 28th)Tetrachlorodibenzodioxin: A chemical by-product that results from burning or incinerating chlorinated industrial chemicals and other hydrocarbons. This compound is considered an environmental toxin, and may pose reproductive, as well as, other health risks for animals and humans.Hydrocarbons, Chlorinated: Hydrocarbon compounds with one or more of the hydrogens replaced by CHLORINE.Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring.Methylmercury Compounds: Organic compounds in which mercury is attached to a methyl group.Environmental Monitoring: The monitoring of the level of toxins, chemical pollutants, microbial contaminants, or other harmful substances in the environment (soil, air, and water), workplace, or in the bodies of people and animals present in that environment.Cadmium Poisoning: Poisoning occurring after exposure to cadmium compounds or fumes. It may cause gastrointestinal syndromes, anemia, or pneumonitis.Mercury PoisoningFlame Retardants: Materials applied to fabrics, bedding, furniture, plastics, etc. to retard their burning; many may leach out and cause allergies or other harm.Cadmium: An element with atomic symbol Cd, atomic number 48, and atomic weight 114. It is a metal and ingestion will lead to CADMIUM POISONING.Pica: The persistent eating of nonnutritive substances for a period of at least one month. (DSM-IV)Great Lakes Region: The geographic area of the Great Lakes in general and when the specific state or states are not indicated. It usually includes Illinois, Indiana, Michigan, Minnesota, New York, Ohio, Pennsylvania, and Wisconsin.Pesticide Residues: Pesticides or their breakdown products remaining in the environment following their normal use or accidental contamination.Phenyl Ethers: Ethers that are linked to a benzene ring structure.Mercury Compounds: Inorganic compounds that contain mercury as an integral part of the molecule.Occupational Exposure: The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.Dental Amalgam: An alloy used in restorative dentistry that contains mercury, silver, tin, copper, and possibly zinc.Succimer: A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.Seafood: Marine fish and shellfish used as food or suitable for food. (Webster, 3d ed) SHELLFISH and FISH PRODUCTS are more specific types of SEAFOOD.Cesium Radioisotopes: Unstable isotopes of cesium that decay or disintegrate emitting radiation. Cs atoms with atomic weights of 123, 125-132, and 134-145 are radioactive cesium isotopes.Milk, HumanHydrocarbons, BrominatedLead PoisoningDichlorodiphenyl Dichloroethylene: An organochlorine pesticide, it is the ethylene metabolite of DDT.Hair: A filament-like structure consisting of a shaft which projects to the surface of the SKIN from a root which is softer than the shaft and lodges in the cavity of a HAIR FOLLICLE. It is found on most surfaces of the body.Water Pollutants, Chemical: Chemical compounds which pollute the water of rivers, streams, lakes, the sea, reservoirs, or other bodies of water.Fishes: A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.Cost of Illness: The personal cost of acute or chronic disease. The cost to the patient may be an economic, social, or psychological cost or personal loss to self, family, or immediate community. The cost of illness may be reflected in absenteeism, productivity, response to treatment, peace of mind, or QUALITY OF LIFE. It differs from HEALTH CARE COSTS, meaning the societal cost of providing services related to the delivery of health care, rather than personal impact on individuals.Metallurgy: The science, art, or technology dealing with processes involved in the separation of metals from their ores, the technique of making or compounding the alloys, the techniques of working or heat-treating metals, and the mining of metals. It includes industrial metallurgy as well as metallurgical techniques employed in the preparation and working of metals used in dentistry, with special reference to orthodontic and prosthodontic appliances. (From Jablonski, Dictionary of Dentistry, 1992, p494)Fish Products: Food products manufactured from fish (e.g., FISH FLOUR, fish meal).Soil Pollutants: Substances which pollute the soil. Use for soil pollutants in general or for which there is no specific heading.Epidemiological Monitoring: Collection, analysis, and interpretation of data about the frequency, distribution, and consequences of disease or health conditions, for use in the planning, implementing, and evaluating public health programs.Metals, Heavy: Metals with high specific gravity, typically larger than 5. They have complex spectra, form colored salts and double salts, have a low electrode potential, are mainly amphoteric, yield weak bases and weak acids, and are oxidizing or reducing agents (From Grant & Hackh's Chemical Dictionary, 5th ed)Insecticides: Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.Air Pollutants, Occupational: Air pollutants found in the work area. They are usually produced by the specific nature of the occupation.MichiganFurans: Compounds with a 5-membered ring of four carbons and an oxygen. They are aromatic heterocycles. The reduced form is tetrahydrofuran.Diet: Regular course of eating and drinking adopted by a person or animal.Chelating Agents: Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.Tissue Distribution: Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.Maternal Exposure: Exposure of the female parent, human or animal, to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals that may affect offspring. It includes pre-conception maternal exposure.New YorkHousing: Living facilities for humans.Breast Feeding: The nursing of an infant at the breast.Half-Life: The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Relationships between environmental organochlorine contaminant residues, plasma corticosterone concentrations, and intermediary metabolic enzyme activities in Great Lakes herring gull embryos. (1/556)

Experiments were conducted to survey and detect differences in plasma corticosterone concentrations and intermediary metabolic enzyme activities in herring gull (Larus argentatus) embryos environmentally exposed to organochlorine contaminants in ovo. Unincubated fertile herring gull eggs were collected from an Atlantic coast control site and various Great Lakes sites in 1997 and artificially incubated in the laboratory. Liver and/or kidney tissues from approximately half of the late-stage embryos were analyzed for the activities of various intermediary metabolic enzymes known to be regulated, at least in part, by corticosteroids. Basal plasma corticosterone concentrations were determined for the remaining embryos. Yolk sacs were collected from each embryo and a subset was analyzed for organochlorine contaminants. Regression analysis of individual yolk sac organochlorine residue concentrations, or 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEQs), with individual basal plasma corticosterone concentrations indicated statistically significant inverse relationships for polychlorinated dibenzo-p-dioxins/polychlorinated dibenzofurans (PCDDs/PCDFs), total polychlorinated biphenyls (PCBs), non-ortho PCBs, and TEQs. Similarly, inverse relationships were observed for the activities of two intermediary metabolic enzymes (phosphoenolpyruvate carboxykinase and malic enzyme) when regressed against PCDDs/PCDFs. Overall, these data suggest that current levels of organochlorine contamination may be affecting the hypothalamo-pituitary-adrenal axis and associated intermediary metabolic pathways in environmentally exposed herring gull embryos in the Great Lakes.  (+info)

Biomarkers for exposure to ambient air pollution--comparison of carcinogen-DNA adduct levels with other exposure markers and markers for oxidative stress. (2/556)

Human exposure to genotoxic compounds present in ambient air has been studied using selected biomarkers in nonsmoking Danish bus drivers and postal workers. A large interindividual variation in biomarker levels was observed. Significantly higher levels of bulky carcinogen-DNA adducts (75.42 adducts/10(8) nucleotides) and of 2-amino-apidic semialdehyde (AAS) in plasma proteins (56.7 pmol/mg protein) were observed in bus drivers working in the central part of Copenhagen, Denmark. In contrast, significantly higher levels of AAS in hemoglobin (55.8 pmol/mg protein), malondialdehyde in plasma (0. 96 nmol/ml plasma), and polycyclic aromatic hydrocarbon (PAH)-albumin adduct (3.38 fmol/ microg albumin) were observed in the suburban group. The biomarker levels in postal workers were similar to the levels in suburban bus drivers. In the combined group of bus drivers and postal workers, negative correlations were observed between bulky carcinogen-DNA adduct and PAH-albumin levels (p = 0.005), and between DNA adduct and [gamma]-glutamyl semialdehyde (GGS) in hemoglobin (p = 0.11). Highly significant correlations were found between PAH-albumin adducts and AAS in plasma (p = 0.001) and GGS in hemoglobin (p = 0.001). Significant correlations were also observed between urinary 8-oxo-7, 8-dihydro-2'-deoxyguanosine and AAS in plasma (p = 0.001) and PAH-albumin adducts (p = 0.002). The influence of the glutatione S-transferase (GST) M1 deletion on the correlation between the biomarkers was studied in the combined group. A significant negative correlation was only observed between bulky carcinogen-DNA adducts and PAH-albumin adducts (p = 0.02) and between DNA adduct and urinary mutagenic activity (p = 0.02) in the GSTM1 null group, but not in the workers who were homozygotes or heterozygotes for GSTM1. Our results indicate that some of the selected biomarkers can be used to distinguish between high and low exposure to environmental genotoxins.  (+info)

Lead and hypertension in a sample of middle-aged women. (3/556)

OBJECTIVES: The role of lead exposure as a risk factor for hypertension is less well defined among women than among men. This case-control study assessed the relation of blood and bone lead concentrations to hypertension in women. METHODS: Cases and controls were a subsample of women from the Nurses' Health Study. Hypertension was defined as a physician diagnosis of hypertension between 1988 and 1994 or measured systolic blood pressure > or = 140 mm Hg or diastolic blood pressure > or = 90 mm Hg. RESULTS: Mean (SD) blood lead concentration was 0.15 (0.11) mumol/L; mean tibia and patella lead concentrations by K-x-ray fluorescence were 13.3 (9.0) and 17.3 (11.1) micrograms/g, respectively. After adjustment for potentially confounding factors, an increase from the 10th to the 90th percentile of patella lead values (25 micrograms/g) was associated with approximately 2-fold (95% confidence interval = 1.1, 3.2) increased risk of hypertension. There was no association between hypertension and either blood or tibia lead concentrations. CONCLUSIONS: These findings support a potentially important role for low-level lead exposure as a risk factor for hypertension among non-occupationally exposed women.  (+info)

Impact of diet on lead in blood and urine in female adults and relevance to mobilization of lead from bone stores. (4/556)

We measured high precision lead isotope ratios and lead concentrations in blood, urine, and environmental samples to assess the significance of diet as a contributing factor to blood and urine lead levels in a cohort of 23 migrant women and 5 Australian-born women. We evaluated possible correlations between levels of dietary lead intake and changes observed in blood and urine lead levels and isotopic composition during pregnancy and postpartum. Mean blood lead concentrations for both groups were approximately 3 microg/dl. The concentration of lead in the diet was 5.8 +/- 3 microg Pb/kg [geometric mean (GM) 5.2] and mean daily dietary intake was 8.5 microg/kg/day (GM 7.4), with a range of 2-39 microg/kg/day. Analysis of 6-day duplicate dietary samples for individual subjects commonly showed major spikes in lead concentration and isotopic composition that were not reflected by associated changes in either blood lead concentration or isotopic composition. Changes in blood lead levels and isotopic composition observed during and after pregnancy could not be solely explained by dietary lead. These data are consistent with earlier conclusions that, in cases where levels of environmental lead exposure and dietary lead intake are low, skeletal contribution is the dominant contributor to blood lead, especially during pregnancy and postpartum.  (+info)

Juvenile hypothyroidism among two populations exposed to radioiodine. (5/556)

We found an epidemic of juvenile hypothyroidism among a population of self-defined "downwinders" living near the Hanford nuclear facility located in southeast Washington State. The episode followed massive releases of 131I. Self-reported data on 60 cases of juvenile hypothyroidism (<20 years of age) among a group of 801 Hanford downwinders are presented, as well as data concerning the thyroid status of approximately 160,000 children exposed to radioiodine before 10 years of age as a result of the 26 April 1986 Chernobyl explosion in the former Soviet Union. These children were residents of five regions near Chernobyl. They were examined by standardized screening protocols over a period of 5 years from 1991 to 1996. They are a well-defined group of 10 samples. Fifty-six cases of hypothyroidism were found among boys and 92 among girls. Body burdens of 137Cs have been correlated with hypothyroidism prevalence rates. On the other hand, the group of juvenile (<20 years of age) Hanford downwinders is not a representative sample. Most of the 77 cases of juvenile hypothyroidism in the Hanford group were diagnosed from 1945 to 1970. However, the ratio of reported cases to the county population under 20 years of age is roughly correlated with officially estimated mean levels of cumulative thyroid 131I uptake in these counties, providing evidence that juvenile hypothyroidism was associated with radioiodine exposures. Because even subtle hypothyroidism may be of clinical significance in childhood and can be treated, it may be useful to screen for the condition in populations exposed to radioiodine fallout. Although radiation exposure is associated with hypothyroidism, its excess among fallout-exposed children has not been previously quantified.  (+info)

Estimation of the dermal absorption of m-xylene vapor in humans using breath sampling and physiologically based pharmacokinetic analysis. (6/556)

A physiologically-based pharmacokinetic model, containing a skin compartment, was derived and used to simulate experimentally determined exposure to m-xylene, using human volunteers exposed under controlled conditions. Biological monitoring was conducted by sampling, in exhaled alveolar air and blood, m-xylene and urinary methyl hippuric acid concentrations. The dermal absorption of m-xylene vapor was successfully and conveniently studied using a breath sampling technique, and the contribution to m-xylene body burden from the dermal route of exposure was estimated to be 1.8%. The model was used to investigate the protection afforded by an air-fed, half-face mask. By iteratively changing the dermal exposure concentration, it was possible to predict the ambient concentration that was required to deliver the observed urinary excretion of methylhippuric acid, during and following inhalation exposure to 50 ppm m-xylene vapor. This latter extrapolation demonstrates how physiologically-based pharmacokinetic modeling can be applied in a practical and occupationally relevant way, and permitted a further step not possible with biological monitoring alone. The ability of the model to extrapolate an ambient exposure concentration was dependent upon human metabolism data, thereby demonstrating the mechanistic toxicological basis of model output. The methyl hydroxylation of m-xylene is catalyzed by the hepatic mixed function oxidase enzyme, cytochrome P450 2E1 and is active in the occupationally relevant, (<100 ppm) exposure range of m-xylene. The use of a scaled-up in vitro maximum rate of metabolism (Vmaxc) in the model also demonstrates the increasingly valuable potential utility of biokinetic data determined using alternative, non-animal methods in human chemical-risk assessment.  (+info)

Evaluation of diabetes mellitus, serum glucose, and thyroid function among United States workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. (7/556)

OBJECTIVE: Some studies suggest that exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) may affect glucose metabolism and thyroid function. To further assess the relation between exposure to TCDD and endocrine function, data from the largest morbidity study of industrial workers exposed to TCDD were examined. METHODS: A cross sectional study of workers employed > 15 years earlier in the manufacture of 2,4,5-trichlorophenol or one of its derivatives at two United States chemical plants was conducted. The referent group consisted of people with no occupational exposure to phenoxy herbicides and were recruited from the neighbourhoods where the workers lived. RESULTS: A total of 281 workers and 260 unexposed referents participated. The mean current serum lipid adjusted TCDD concentration among workers was 220 pg/g lipid, and among referents was 7 pg/g lipid (p < 0.05). The half life extrapolated TCDD concentrations (the estimated TCDD concentration when occupational exposure to TCDD stopped) among workers averaged 1900 pg/g lipid (range: not detected--30,000 pg/g lipid). Overall, the prevalence of diabetes mellitus was not significantly different between the workers and referents. Also, there was not a significant positive trend between prevalence of diabetes and increasing serum TCDD concentration. However, diabetes was found in six of 10 (60%) workers with current serum TCDD concentrations > 1500 pg/g lipid. After excluding subjects being treated for diabetes, workers in the group with the highest half life extrapolated TCDD concentrations had a significantly increased adjusted mean serum glucose concentration compared with referents (p = 0.03). Workers were also found to have a significantly higher adjusted mean free thyroxine index compared with referents (p = 0.02), especially among workers in the group with the highest half life extrapolated TCDD concentrations. However, no evidence was found that workers exposed to TCDD were at increased risk of thyroid disease. CONCLUSIONS: These findings provide modest evidence that exposure to TCDD may affect thyroid function and glucose metabolism.  (+info)

Follow up of workers previously exposed to silver solder containing cadmium. (8/556)

OBJECTIVES: To study longitudinal biological monitoring data on urinary and blood cadmium collected in a small cohort of nine workers who had been brazing for several years with solders containing cadmium. METHODS: Cadmium was measured by neutron activation analysis in livers and kidneys, and estimates of renal function were carried out in 1983 and 1995. During the intervening period exposure to cadmium was dramatically reduced by local exhaust ventilation control and substitution of the solder containing cadmium. RESULTS: From urinary protein measurements there was evidence within the group of increasing renal tubular damage over the 12 year period, even though exposure to cadmium was dramatically reduced over this period and almost eliminated by 1995. There was no evidence from serum creatinine of decreasing glomerular filtration rate, and the renal tubular handling of calcium, phosphate, or urate had not worsened significantly. Blood and urinary cadmium concentrations reduced significantly over the 12 year period but were still substantial in 1995. Blood cadmium concentrations tended to reflect cadmium body burden in 1995 when exposure had been low for several years, and decreased most significantly during 1983-90. By contrast urinary cadmium concentrations only decreased significantly from about 1990 onwards. Urinary cadmium was not significantly correlated with liver or kidney cadmium concentration in either 1983 or 1995. This may be due to the level of tubular dysfunction in the cohort. Calculated cumulative excretion of cadmium over the 12 year period was substantially greater than the loss of cadmium measured in livers and kidneys and the derived loss in body burden. Reasons for this are discussed. It is possible that in cohorts, where renal damage is apparent, urinary concentrations reflect a substantial component of current exposure rather than stored body losses. CONCLUSIONS: The data reinforce the concept that blood cadmium concentrations may not always reflect recent exposure, but may reflect body burden derived from historical exposure depending on the degree of current exposure; and that the decline in urinary and blood cadmium measurements after removal from, or reduction in, exposure will be slow and depend on the historical body burden.  (+info)

Accumulation, elimination and subcellular distribution of heavy metals in Littorina brevicula exposed to cadmium and zinc, both alone and in combination were investigated. When L. brevicula was exposed to CdCl₂ 400 mg/L and ZnSO₄ 3000 mg/L separately for 90days, each of the metal body burden in the whole soft parts increased in proportion to time of exposure until 70days. But it dosent increase after 70days. When the winkles were exposed to cadmium and zinc simultaneously, zinc body burden increased and cadmium body burden decreased as compared with when they were exposed to each of the metal. We also found that cadmium accumulated in the winkles was not depurated for 42days, but zinc accumulated in them was depurated. Especially, zinc was depurated faster when they had been exposed to mixture of cadmium and zinc. After the winkles had been exposed to cadmium and zinc separately for 70days, cadmium was mainly associated with the soluble fraction(about 60% of the total body burden), while ...
If you are thinking about having a baby, if you are pregnant, or if you just had a baby, consider taking action to reduce your babys chemical "body burden." This series of articles will help you make decisions to reduce the chemicals in your childs blood as they grow giving them better chances for long-term health. Numerous studies in the past decade on cord blood, blood, and breast milk are showing that everyone in the world has pollution in their blood. Environmental Working Groups 2005 Study, "Body Burden-The Pollution in Newborns," found some horrifying results:. "Of the 287 chemicals we detected in umbilical cord blood, we know that 180 cause cancer in humans or animals, 217 are toxic to the brain and nervous system, and 208 cause birth defects or abnormal development in animal tests. The dangers of pre- or post-natal exposure to this complex mixture of carcinogens, developmental toxins, and neurotoxins have never been studied.". This is called our "body burden." The pollution is from ...
In a study spearheaded by the Environmental Working Group (EWG), researchers at two major laboratories found an average of 200 industrial compounds, pollutants, and other chemicals in 10 newborn babies, with a total of 287 chemicals found in the group. To our knowledge this work represents the first reported cord blood tests for 261 of the targeted chemicals, and the first reported detections of at least 209 chemicals. Scientists refer to this contamination as a persons body burden.
More and more people are demanding the right to know what chemicals are in their bodies. In California, a bill is being pushed that would set up the first statewide biomonitoring system to collect and analyze breast milk. But some fear testing might cause people to confuse chemical exposure with illness and cause undue alarm. Living on Earths Ingrid Lobet reports.
In the three years since her family went through body burden testing, Michelle Hammond has become an activist on the issue. Shes testified twice in the California legislature to support a statewide body burden testing program, a bill that passed last year. Michelle also speaks to various public health groups about her experience, taking Mikaela, now 8, and Rowan, now 5, with her. So far, her children show no health problems associated with the industrial chemicals in their bodies ...
Author of Green Goes with Everything: Simple Steps to a Healthier Life and a Cleaner Planet, Sloane Barnet recently wrote in the Huffington Post, Most
In the month leading up to a babys birth, the umbilical cord pulses with the equivalent of at least 300 quarts of blood each day, pumped back and forth from the nutrient- and oxygen-rich placenta to the rapidly growing child cradled in a sac of amniotic fluid. This cord is a lifeline between mother and baby, bearing nutrients that sustain life and propel growth.
The objectives of this study were to determine whether Drug Burden Index (DBI), a measure of individuals exposure to anticholinergic and sedative drugs, and Beers criteria, an explicit measure of potentially inappropriate drug use, are associated wi
Persistent chlorinated organic compounds (PCBs, PCDDs, PCDFs, HCB, DDTs, etc.) have varying harmful effects on human health (1). Humans are mainly exposed to these compounds by consuming diary products, meat and fish. Newborns are prenatally exposed across the placenta and post partum through breastfeeding (2). The primary storage sites are adipose tissue and liver. Monitoring concentrations of organohalogen contaminants in human fluids and tissues is one of the important steps necessary for health risk assessment. Breast milk has been the preferred matrix to evaluate human background exposure and body burden. The analysis of persistent chlorinated organic compounds in the placenta and umbilical blood is important to estimate transplacental exposure. Concentrations in the blood serum reflect best the body burden of the general population. Therefore, a systematic program of sampling and analysis of human body fluids and tissues for selected persistent chlorinated organic compounds has been ...
This paper presents a detailed congener-specific estimate of PCB exposure to the UK population. The average PCB intake (i.e. the sum of IUPAC congeners No. 28, 44, 52, 61/74, 66, 99, 101, 105, 110, 118, 138, 151, 153, 156, 170, 180, 183, 187, 189, 194/205, 201, 202, 206 and 209) for the contemporary UK population was estimated to be 0.53 μg/person/day. Food consumption accounted for 97% of the PCB exposure, with fish, milk and dairy products, vegetables and meat and animal fat accounting for 32, 24, 24 and 15%, respectively. The congener pattern for different food products varied, with vegetables playing a major part in the intake of lower chlorinated compounds, whilst fatty foods such as fish, dairy products and meat, were of greater importance for the intake of higher chlorinated compounds. Theoretical body burdens and body fat concentrations of selected PCB congeners were derived for the UK population, based on the estimated contemporary human daily intake of PCBs and a number of ...
Pentachlorophenol (PCP) is present in most environmental compartments, including those which result in direct human exposure. This paper assesses the contribution made by different exposure routes and illustrates that the average non-occupationally exposed UK individual absorbs 0.05, 0.32 and 4.16 μg PCP per day from air inhalation, water and diet ingestion, giving a total absorption of 4.53 μg (total intake being 5.7 μg). Using data from other sources it appears that most human PCP body burdens are in the region of 550 μg. Using the body burden and calculated daily intakes it is concluded that either the half-life of PCP in the human body has been underestimated or that the UK body burden is below that found in other countries.. ...
An implantable lead body, and method of manufacturing same, and system for stimulation. The lead body includes an expanding/expansion section providing an additional length or slack in the lead body and allowing the lead body to expand or stretch with the body thereby reducing or eliminating the mechanical force or strain on the ends of the lead at the destination sites.
Ed Browns new movie Unacceptable Levels tells the story of chemicals in our bodies: how they get there, what it means to our health, how in the world it can be legal, and what we can do about it.. All this from the perspective of a young dad contemplating the food his family eats, the water they drink and that cute little rubber duck his kids chew on. Browns personal journey, as he pulls back the veil on our chemically-saturated world, is well worth watching. Ill be at the films July 11 screening in San Francisco along with other PAN staff - if youre in the Bay Area, please join us! Showings are also happening soon in Chicago and Austin.. ...
The Polychlorinated Biphenyls (PCBs) Profile can help identify which of the most toxic PCBs a patient has been exposed to and the body burden of the patient.
Performance limitations are the consequence of biochemical imbalances and toxic body-burden. Optimum performance can be achieved by correcting biochemistry and endocrine function. The levels of nutrient (and toxic) minerals have an impact on how well biological processes function. Canine physical and cognitive abilities can be improved.
The retention, distribution, metabolism, and excretion of [14C]octamethylcyclotetrasiloxane (D4) were studied in Fischer 344 rats after single and multiple exposures to 7, 70, or 700 ppm [14C]D4. Subset groups were established for body burden, distribution, and elimination. Retention of inhaled D4 was relatively low (5-6% of inhaled D4). Radioactivity derived from [14C]D4 inhalation was widely distributed to tissues of the rat. Maximum concentrations of radioactivity in plasma and tissues (except fat) occurred at the end of exposure and up to 3 h postexposure. Maximum concentrations of radioactivity in fat occurred as late as 24 h postexposure. Fat was a depot, elimination of radioactivity from this tissue was much slower than from plasma and other tissues. With minor exceptions, there were no consistent gender effects on the distribution of radioactivity and the concentrations of radioactivity were nearly proportional to exposure concentration over the exposure range. Excretion of radioactivity ...
According to Peter Montague, editor of Rachels Health and Environment Weekly, in any given group of 1,000 different chemicals there are 41 billion possible combinations of groups of 4. 2 Synthesis also occurs when the chemicals found in cleaning products interact with materials found in the environment. Chlorine, for example, can combine with natural organic materials found in dirt and soils to create a variety of carcinogenic chlorinated hydrocarbons, including toxins like chloroform and trihalomethanes. Qxd 1/31/06 20 10:59 AM Page 20 N AT U R A L LY C L E A N mulated toxic contaminants we have ingested over time by breathing polluted air, eating food with toxic residues, drinking contaminated water, and exposing our skin to dangerous chemicals. In the last few years, scientists have begun to examine our body burdens in detail, and what theyve discovered is discomforting at best. Theyve found that the body of the average American is littered with countless toxic chemicals. 1 ≈ According ...
Our modern world is flooded with pollution, food additives, drugs, chemicals and heavy metals. We ingest them through the air we breathe, the food we eat and sometimes the water we drink. At times our habits add further toxins to our systems, such as through smoking, caffeine intake and alcohol use. The accumulation of such substances in the body contributes to a "body burden" of toxins and can lead to chronic disease. By removing or eliminating toxins and replenishing the body with healthy nutrients, we can help protect against disease and restore the ability to maintain complete wellbeing. Detoxification programs also jump start weight loss, while supporting hormonal and metabolic health ...
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Also avoid sodium lauryl sulfite (SLS), these products are often labeled SLS free.. Iodine - Missing Protection from our Food Supply.. Thirty years ago iodine (Read more about iodine is needed) was removed from our bread and replaced with bromide (Bromide affects your thyroid!). Since that time breast cancer rates and thyroid dysfunction have sky rocketed to epidemic levels and continue to climb ever higher, as your food gets worse and our total body burden of chemicals and heavy metals climbs higher. Hypothroidism is very common today and our average body temperature is no longer 98.6. Having a temperature of 98.6 is imperative because the liver performs many functions and depends on the correct body temperature for those enzymatic processes to occur.. Iodine, chlorine, bromine and fluoride are all halides, except only iodine is a healthy halide, the others belong in a class referred to as "toxic halides." Eating bread, taking a shower, and brushing your teeth can all be dangerous to your ...
Find ferro vanadium, vanadium pentoxide from JAISWALS OXIDES & PIGMENTS CO. PVT. LTD - We are an acknowledged manufacturer, exporter & supplier of ferro vanadium, vanadium pentoxide, sodium metavanadate and many more chemicals from Chhattisgarh, India.
CHAPTER 599. An act to add Chapter 8 (commencing with Section 105440) to Part 5 of Division 103 of the Health and Safety Code, relating to public health.. The chaptered bill in PDF format.. On December 11, participants in the Boston Consensus Conference on Biomonitoring presented their consensus statement. This event was the culmination of 2 1/2 months of hard work by a group of 14 Boston-area residents who met over three weekends in Fall 2006 to learn about and consider issues related to biomonitoring, and to have their questions answered by national experts. The results of their deliberations present an important opportunity to provide public input on the topic to policymakers, researchers, advocacy groups, and others.. http://www.biomonitoring06.org/ The Consensus statement in PDF format. ...
Dr. Robley D. Evans, professor emeritus of physics at the Massachusetts Institute of Technology, winner of the 1990 Enrico Fermi Award and a pioneer in studying the effects of radium on the human body, died December 31 in Paradise Valley, AZ, where he lived in retirement. He was 88.. His family said the cause of death was respiratory failure.. There were no services.. Professor Evans was a founder of nuclear medicine and established the standard, used throughout the world, for the maximum permissible body burden of radium.. The Department of Energy said in its citation accompanying the Fermi Award, that Professor Evans did pioneering work "in measurements of body burdens of radioactivity and their affects on human health, and in the use of radioactive isotopes for medical purposes.". The Fermi Award is the highest scientific award given by the DOE. It recognizes "exceptional and altogether outstanding scientific and technical achievement in the development, use or control of atomic energy. The ...
The reactive surface and layered crystal structure of vanadium pentoxide (V2O5) are exploited here to prepare a two-dimensional (2D) ion pump that transports ions against their concentration gradient. The exfoliated layers of V2O5 were assembled into membrane form to create ion-channels with excellent nanofluidic t
A medical lead which has a connector assembly coupled to an electrode by a lead body, the lead body is designed so as to have greater resistance to crush fatigue in the area which is located between the rib and clavicle when implanted. In particular the lead body of the present invention features an insulative sheath covering a coiled conductor. The coiled conductor has three sections, viz., proximal, intermediate and distal sections. The intermediate section has a different pitch as compared to proximal section and distal section. In the preferred embodiment, intermediate section has a pitch of approximately 0.100 while proximal section has a pitch of approximately 0.025 and distal section has a pitch of approximately 0.025. Moreover, intermediate section has a length of approximately 10.4 inches while proximal section has a length of approximately 5.1 inches and distal section has a length of approximately 7.2 inches. In such a manner the lead of the present invention presents a coiled conductor
A lead assembly adapted for endocardial fixation to a human heart is provided. The lead assembly includes a lead body that has a proximal end provided with a connector for electrical connection to a cardiac stimulator. The cardiac stimulator may be a pacemaker, a cardioverter/defibrillator, or a sensing instrument. The distal end of the lead body is connected to a tubular electrode housing. The lead body consists of a noncoiled conductor cable surrounded by a coextensive insulating sleeve. In contrast to conventional leads, the lead body of the present invention does not require coiled conductor wires or an internal lumen. Manipulation of the lead body is via an external guide tube. Lead body diameters of 0.25 mm or smaller are possible.
An assembly is provided for an implantable medical lead. The assembly includes a first lead body comprising one or more electrical leads, and a hermetic encasement. The encasement comprises a housing having first and second openings and interior walls, an interior space defined by the interior walls, an electronic network housed within the interior space, and a circuit board extending through the first and second openings. The circuit board comprises a plurality of layers into which the electronic network is at least partially integrated, a first set of one or more terminals electrically coupling the electronic network to the first lead body, and a second set of one or more terminals electrically coupled to the electronic network for external electrical engagement.
A lead includes a lead body extending from a proximal end to a distal end and having an intermediate portion. A shocking electrode is disposed proximate the distal end of the lead body, and a pacing electrode is disposed along the intermediate portion of the lead body. The distal end of the lead body includes a preformed biased shape.
This product was added to our catalog on August 3, 2016.This is a replacement Ares 18A Brushless ESC with built-in BEC for the Alara EP. AZSA1710
A lead includes a lead body extending from a distal end to a proximal end, and at least one conductor disposed within the lead body and extending from the distal end to the proximal end of the lead body. The lead further includes an outer terminal ring, a terminal pin, and an insulative sleeve disposed between the outer terminal ring and the terminal pin, where the insulative sleeve is coupled with the outer terminal ring with a snap-fit connection. A pin latch is disposed on an outer periphery surface of the insulative sleeve, where the pin latch is rotatable about a hinge point.
Electron paramagnetic resonance (EPR) dosimetry using the well established dosimeter material alanine is a generally accepted dosimetric method for measurements of high absorbed doses. Alanine EPR dosimetry is however not sensitive enough for high precision measurements of low (, 5 Gy) absorbed doses using reasonably measurement times and small dosimeters. It has therefore not been possible to fully exploit the benefits of EPR dosimetry for applications in radiation therapy.. The aim of this thesis was to show that sensitive EPR dosimetry is a competitive method for applications in radiation therapy fulfilling the requirements of measurement precision. Our strategy for reaching this goal was to search for new, more sensitive, EPR dosimeter materials fulfilling the criteria of being tissue equivalent, having a high radical yield and having a narrow EPR spectrum suitable for dosimetry. The best materials were found among formates and dithionates. Doping with small amounts of metal ions and ...
A new test approved by the FDA for diagnosing damage that has been caused by toxic metals like mercury is the fractionated porphyrin test (260), that measures amount of damage as well as likely source. Provocation challenge tests after use of chemical chelators such as DMPS or DMSA also are effective at measuring body burden (57), but can be dangerous to some people- especially those still having amalgam fillings or those allergic to sulfur drugs or sulfites. Many studies using chemical chelators such as DMPS or DMSA have found post chelation levels to be poorly correlated with prechelation blood or urine levels (57,115,303), but one study (340) found a significant correlation between pre and post chelation values when using DMPS. Challange tests using DMPS or DMSA appear to have a better correlation with body burden and toxicity symptoms such as concentration, memory, and motor deficits (290)- with many studies finding a significant correlation between post chelation mercury level and the ...
Purpose: Size, shape, and the position of paired organs are different in abdomen. However, the counterpart organs are conventionally treated jointly together in internal dosimetry. This study was performed to quantify the difference of specific absor
A lead body includes an electrode coupled to an intermediate portion of the lead body. A distal end of the lead includes a pre-formed, biased shape adapted to passively fixate the distal end of the lead within a pulmonary artery with the electrode positioned in the right ventricle or ventricular outflow tract. The lead body can include a preformed J-shape, with the electrode coupled to the intermediate portion of the lead body and located distally from a bottom of the pre-formed J-shape. The lead body can include a section of the intermediate portion of the lead body being less stiff than adjacent sections of the lead body with the electrode coupled to the intermediate portion of the lead body and located distally from the less stiff section.
Turning to adverse effects of plastic on the human population, there is a growing body of literature on potential health risks. A range of chemicals that are used in the manufacture of plastics are known to be toxic. Biomonitoring (e.g. measuring concentration of environmental contaminants in human tissue) provides an integrated measure of an organisms exposure to contaminants from multiple sources. This approach has shown that chemicals used in the manufacture of plastics are present in the human population, and studies using laboratory animals as model organisms indicate potential adverse health effects of these chemicals (Talsness et al. 2009). Body burdens of chemicals that are used in plastic manufacture have also been correlated with adverse effects in the human population, including reproductive abnormalities (e.g. Swan et al. 2005; Swan 2008; Lang et al. 2008).. Interpreting biomonitoring data is complex, and a key task is to set information into perspective with dose levels that are ...
A lead includes a lead body extending from a proximal end to a distal end and having an intermediate portion. A shocking electrode is disposed proximate the distal end of the lead body, and a pacing electrode is disposed along the intermediate portion of the lead body. The distal end of the lead body includes a pre-formed biased shape.
For over 35 years, Biokinetics mission has been to protect the human body from blunt impact injury, ballistic threats and blast effects.
The overall aim of the Concerted Action RBDATA-EULEP is to provide information to improve the assessments of intakes of radionuclides and of the resulting doses. This involves a review of the behaviour of radionuclides following intake, and the transfer of expertise on methodology by organising small training workshops. The main activity is the development of an electronic database, effectively an annotated bibliography, but the electronic format used facilitates extension, updating, and information retrieval. It consists of linked tables of references and experiments, with details and comments on the materials, procedures and results. By June 2002 it contained information on 524 inhalation, 282 ingestion and 164 injection experiments from 391 references. It will be extended, and Internet access provided. Prospective users include: groups developing standards for internal dosimetry, scientists conducting research on radionuclide biokinetics, and health physicists assessing the consequences of ...
This astonishing new discovery underscores the importance for all of us in taking preventive measures to reduce the levels of the neurotoxin, aluminium in our bodies. Professor Exleys recommendation , based on his own clinical trial (read press release here, paper here) is to drink everyday a litre of silicon rich natural mineral water such as SPRITZER.. Drinking a silicon-rich mineral water on a daily basis is a safe, effective, and non-invasive way of removing aluminium from our bodies, as the silicic acid (soluble silicon) is able to cross the gut wall and bind with the aluminium particles in the blood . These are then naturally flushed out by the body through the urine, hence reducing an individual body burden of aluminium daily.. ...
The noncarcinogenic effects of arsenic are reviewed. Included are its toxicity, threshold limit value compared with other toxic substances, use as a poison, arsenic levels in food, body burden in various tissues, the arsenic cycle in nature, signs and symptoms of arsenic poisoning in man and animals, enzymes inhibited by arsenic, blocking by arsenite of the conversion of malate to fumarate or vice
Atlantic Ltd. could produce vanadium trioxide and vanadium pentoxide in addition to ferrovanadium at its Windimurra operation in Australia.
Atlantic Ltd. could produce vanadium trioxide and vanadium pentoxide in addition to ferrovanadium at its Windimurra operation in Australia.
A lead assembly for an implantable medical device includes a lead body having a proximal end and a distal end. One or more connectors at the proximal end of the lead body are each adapted for connection to a pulse generator. One or more conductive elements are coupled to the one or more connectors at the proximal end and extend through the lead body to the distal end. Each of the one or more conductive elements includes an electrode coil that extends from the distal end of the lead body that is formed into a helix having a diameter greater than a diameter of the electrode coil.
Techniques are disclosed for estimating patient radiation exposure during computerized tomography (CT) scans. More specifically, embodiments of the invention provide efficient approaches for generatin
An implantable subcutaneous device includes a lead and electrode for cardiac monitoring and intervention. The device has an implantable lead including a lead body, a subcutaneous electrode supported by the lead body and a pharmacological agent impelled from the device using phoresis. The pharmacological agent provides a therapeutic treatment to subcutaneous non-intrathoracic tissue. A method of implanting subcutaneous leads involves providing a lead including a lead body, a subcutaneous electrode, and a pharmacological agent and using phoresis to impel the pharmacological agent into subcutaneous non-intrathoracic tissue surrounding the lead.
In this case study, you are asked to make qualitative observations about the effect of temperature on the decomposition of nitrogen pentoxide. You are also asked to investigate the question: does the time required for a given fraction of a reactant to decompose via a first order reaction depend on the concentration? In other words, how much time does it take for half of a starting concentration of N2O5 to decompose?. The reaction mechanism is:. ...
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Çiğ Börek İçin Gerekli Malzemeler 200 gram un 250 gram kıyma 1 baş soğan 1 yumurta 200 gram yağ Tuz Karabiber Kızartma için yağ 1 Kaşık salça Böreğin Yapılışı 500 gram unu hamur tahtasına eleyiniz. Yumurta ve tuzu koyup ılık su ile kulak memesi yumuşaklığında hamur yapınız. Yarım limon büyüklüğünde parçalara ayırıp ıslak bez altında…
The internal dosimetry program conducts analyses and consultation for the study and management of internal radiation exposure. The analyses include collection of information on work and residence history, past and current radiation exposure, bioassays to measure the presence of radionuclides within body tissues (in vivo) or body fluids and excretions (in vitro), and calculation of dose associated with observed uptakes. Consultation includes interpretation of bioassay results and can extend to collaboration with health care professionals and workplace supervisors. The internal dosimetry program includes a documented quality assurance program for in vivo bioassays and a comprehensive technical basis for the assessment of internal exposure. The program meets the requirements and recommendations of the DOE Implementation Guide for Internal Dosimetry Programs (10 CFR 835) and the American National Standards Institute Performance Criteria for Radiobioassay (N13.30). The Center is also involved in the ...
TY - JOUR. T1 - Dose estimation for repeated phosphorus-32 ingestion in human subjects. AU - Chao, J. H.. AU - Tseng, C. L.. AU - Hsieh, W. A.. AU - Hung, D. Z.. AU - Chang, W. P.. PY - 2001/1/15. Y1 - 2001/1/15. N2 - Dose estimation was conducted for internal phosphorus-32 exposure in one young male subject from repeated oral mis-ingestion for ,1 year. Since disclosure for previous continuous contamination, a series of urine samples were collected from this individual weekly for a period of ,2 months. P-32 radioactivity in urine samples were measured by the acid precipitation method. Estimation for retrospective total effective dose equivalent received by this subject was conducted for cumulative internal dose estimation. A minimum of 9.4 mSv was estimated for an assumed single ingestion. As this was a rare case in radiation protection and internal radiation dosimetry, its implications were of considerable significance. (C) 2000 Elsevier Science Ltd.. AB - Dose estimation was conducted for ...
Experimental studies have shown that dioxin-like chemicals may interfere with aspects of the endocrine system including growth. However, human background population studies are, however, scarce. We aimed to investigate whether early exposure of healthy infants to dioxin-like chemicals was associated …
Synthesis, structure, and properties of vanadium pentoxide nanotubes / A. V. Grigorieva, A. B. Tarasov, E. A. Goodilin et al. // Glass Physics and Chemistry. - 2007. - Vol. 33, no. 3. - P. 232-236. Vanadium oxide nanotubes are synthesized by the hydrothermal method with the use of polycrystalline vanadium oxide V2O5 and 1-hexadecylamine as a structural template. The structure of the vanadium oxide nanotubes is investigated using small-angle X-ray diffraction and transmission electron microscopy. It is demonstrated that the structure of the vanadium oxide nanotubes is characterized by a combination of fragments with different interlayer distances associated with the twisting of oxide layers in the form of "nanorolls." The thermal stability, morphology, and surface properties of the nanotubes, as well as the role of the organic template in the formation of their structure, are discussed. [ DOI ...
In connection with clinical 131I-MIBG studies of patients with suspected pheochromocytoma and adrenomedullary hyperplasia quantitative biokinetic data have been collected in order to improve the present estimations of absorbed dose to various organs and tissues. Whole-body profiles as a function of time were measured with a whole-body counter. The retention in the total body and in the thyroid gland could be derived from the measured whole-body profiles by summing up the corresponding values. The retention of 131I-MIBG could not be exactly measured for further organs from the whole-body profiles in man. For this reason animal studies were performed with mice. The biokinetic animal data were transferred to man in form of the cumulative activity for the various organs. The mean absorbed dose for selected organs per injected activity unit was calculated using the concept of absorbed fractions (MIRD method) taking into account the radioactivity within the remaining body. Except for both the adrenal medulla
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Decreasing Patient Radiation Dose from CT Imaging: Achieving Sub-mSv Studies (U01) PAR-12-206. NIBIB
These substances are used for the whole plastic production process and are linked to various diseases. Some of the substances are known to have a mutagenic effect and can lead to cancer. Some are suspected of being mutagenic. Others have endocrine disrupting effects that can promote cancer and other illnesses linked to the endocrine system like reproductive health impacts. A study shows that the exposure in the plastic industry poses women at disproportionate risk. It also shows the need for regulatory action.44 Women in the plastics industry have a significantly higher body burden than unexposed workers and the general population. A Canadian study shows that women working in automotive plastics and food canning industries have fivefold increase in pre-menopausal breast cancer.45 The study also claims that "Despite concern about the harmful effects of substances contained in various plastic consumer products, little attention has focused on the more heavily exposed women working in the plastics ...
The ecological relevance of the neutral red retention assay as a biomarker in an indigenous earthworm population (Microchaetus sp.) exposed to the fungicide copper oxychloride was investigated. Changes in earthworm biomass and numbers were monitored and related to changes in neutral red retention times of coelomocytes as well as changes in copper concentrations in the soil and earthworm body tissues. Results indicated that Microchaetus sp. responded sensitively to the copper oxychloride by showing an initial decrease in biomass 2 months after spraying started. This was followed by a significant decrease in worm numbers after 3 months. The neutral red retention times of earthworm coelomocytes decreased significantly within the first month of treatment and correspond to a significant increase in soil copper concentrations, but not with an immediate increase in body burdens of copper. More than a year after spraying had stopped the worm biomass and numbers were still significantly lower in the ...
I have a CHOCOLATE FOREVER sticker posted on my forehead. Glad to hear I can indulge again. As for popcorn, however, hem-hem. I would advise avoiding microwave bags because the inside of most brands is treated with a chemical that is very, very bad for people. It stays in your body, increasing your body burden. There is one brand that does not use it, but I forget the name, so I avoid microwave popcorn, period. The second issue is GMO corn. Most corn in the USA is, unfortunately, GMO. We need to avoid GMOs. Why? They have not been adequately tested. Tests on rodents show that future generations have deformities. This has not been proved, but when in doubt .... at least make sure to demand that GMOs get labeled so those of us who chose to have viable descendants can avoid the stuff. Many countries in Europe have outlawed GMOs. So far the very powerful Monsanto chemical lobby has managed to contribute enough $ so that our Congress resists labels. 80% of the food in supermarkets is now GMO. ...
Founded at the early of 1990s, Chuzhou Fine Chemical Factory is a specialized manufacturer of Phosphorus pentoxide (dried by Sulfuric acid), with an annual output of 5,000 tons of Phosphorus pentoxide and 2,000 tons of Polyphosphoric acid.
Independent ten year review of NIOSHs activities under Subtitle B of EEOICPA. Examines the quality of science, timeliness of task accomplishments, special exposure cohort, dose reconstructions, and quality of service.
A biomedical stimulation lead wherein the lead body is preformed into a helical configuration to assist in anchoring the lead. The lead includes a non-conducting member extending forward of the lead electrode along the axis of the lead body, and tines extending perpendicularly from the member. The tines are flat in a plane perpendicular to the axis of the lead.
This page was last edited 17:09, 18 September 2017 by wikidoc user . Based on work by Kalsang Dolma, Daniel Nethala, Vishnu Vardhan Serla, Katherine Ogando, Alara Eren, Scott Williams, Jacki Buros (bot), [email protected] and Alexandra Almonacid, wikidoc user and wikidoc anonymous user Arcadian ...
Thank you for your questions and thoughts. Missing a single dose is rarely sufficient to cause problems with treatment failure or resistance. However, frequent missed doses can definately place...
To expedite the licensing process of the non site specific Centralized Interim Storage Facility (CISF) the Department of Energy has completed a phase I CISF Topical Safety Analysis Report (TSAR). The TSAR will be used in licensing the phase I CISF if a site is designated. An occupational radiation does assessment of the facility operations is performed as part of the phase I CISF design. The first phase of the CISF has the capability to receive, transfer, and store SNF in dual-purpose cask/canister systems (DPC`s). Currently there are five vendor technologies under consideration. The preliminary dose assessment is based on estimated occupational exposures using traditional power plant ISFSI and transport cask handling processes. The second step in the process is to recommend ALARA techniques to reduce potential exposures. A final dose assessment is completed implementing the ALARA techniques and a review is performed to ensure that the design is in compliance with regulatory criteria. The dose
Cadmium is a carcinogenic heavy metal. Urinary levels of cadmium are considered to be an indicator of long-term body burden, as cadmium accumulates in the kidneys and has a half-life of at least 10 years. However, the temporal stability of the biomarker in urine samples from a non-occupationally exposed population has not been rigorously established. We used repeated measurements of urinary cadmium (U-Cd) in spot urine samples and first morning voids from two separate cohorts, to assess the temporal stability of the samples.
Electron paramagnetic resonance (EPR) dosimetry using the well established dosimeter material alanine is a generally accepted dosimetric method for measurements of high absorbed doses. Alanine EPR dosimetry is however not sensitive enough for high precision measurements of low (, 5 Gy) absorbed doses using reasonably measurement times and small dosimeters. It has therefore not been possible to fully exploit the benefits of EPR dosimetry for applications in radiation therapy.. The aim of this thesis was to show that sensitive EPR dosimetry is a competitive method for applications in radiation therapy fulfilling the requirements of measurement precision. Our strategy for reaching this goal was to search for new, more sensitive, EPR dosimeter materials fulfilling the criteria of being tissue equivalent, having a high radical yield and having a narrow EPR spectrum suitable for dosimetry. The best materials were found among formates and dithionates. Doping with small amounts of metal ions and ...
The situation in Italy regarding radiation dose to patients undergoing Multidetector row Computed Tomography (MDCT) scans is unclear despite Italian law
Svante Arrhenius väg 8, Stockholm. Arrheniuslaboratoriet, Svante Arrhenius väg 16, Stockholm (Unit for Analytical and Toxicological Chemistry). Mailing address: ...
By their very nature children are more sensitive to pesticides than adults. A childs body continues to grow until 18 but their brain and nervous system are under development until the age of 25. We are all exposed to more chemicals than ever before but can you imagine the body burden our children are experiencing while their systems are growing? Is it any wonder that cancer rates are on the rise in our children?. On October 22, 2012 there was a report released in The Journal of Pediatrics by The American Academy of Pediatrics that spoke to the need for children to eat organic produce and meat. Unfortunately the report did not go far enough. Organic food is a controversial topic and this review is a positive follow up to the poorly constructed study published by Stanford in the Annals of Internal Medicine in September 2012. This particular study strangely concluded that organically grown food has the same nutrition than conventionally grown food.. It has been proven that organic food does ...
The mission of the Radiation Safety program is to assist East Tennessee State University personnel and students in the safe acquisition, handling and disposal of radiation sources. Our goal is to keep radiation exposure to University personnel, members of the public, and the environment As Low As Reasonably Achievable (ALARA) and in compliance with state and federal regulations. ...
Vizard, C. G., Rimmer, D. L., Pless-Mulloli, T., Singleton, I., & Air, V. S. (2006). Identifying contemporary and historic sources of soil polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in an industrial urban setting. Science of the Total Environment, 370(1), 61 - 69. https://doi.org/10.1016/j.scitotenv.2006.06.006. ...
The overall goal of this investigation was to measure the ionizing radiation dose to the cranial meninges from a lifetime of self-reported dental radiography. The first aim was to estimate the radiation-absorbed dose to ...
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Company profile & key executives for Universal Radiation Safety (0146185D:-) including description, corporate address, management team and contact info.
As a function of PM size (PM10-2.5, PM2.5-1 and PM1) and origin (furnace, refining and channeled emissions), lead toxicity and bioaccessibility assessment were performed in a lead recycling plant using complementary biologic and chemical acellular tests. According to their origin, process PM displays differences in metal contents, granulometry and percentage of inhalable fraction. Lead gastric bioaccessibility was relatively low (maximum 25%) in comparison with previous available studies, though due to their high total lead concentrations, significant metal quantities couldreach the circulatory system. Whatever their origin, finest PM1 particles induced the greatest pro-inflammatory response from human bronchial epithelial cells. Moreover, this biological response was correlated with the acellular DiThioThreitol (DTT) assay, suggesting some biological predictive value for such acellular test.
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In the paper "Dose is Not Always What it Seems" Anthony Seibert, professor of radiology, and his colleagues discuss the need to improve dose calculations. They point to an actual case in which a pediatric patient who had scans before and after surgery appeared to receive an overdose on the second CT. Further investigation showed that the problem was a misleading metric - the volume CT dose index (CTDIvol), a standard measure of radiation output in CT. Manufacturers use phantoms along with instruments that measure radiation to assess CTDIvol. However, different companies use phantoms of different sizes. In addition, many dose estimates are based on adult sizes, making pediatric estimates more difficult ...
The scope of the project is to select, identify and characterise reference test sites that will be used for the calibration and characterisation of different sensor types. The study is part of the ESA strategy for ensuring the quality (calibration, validation and operational quality) of data developed for current and future missions within the Explorers and GMES framework. The output of the project can be found in the table below.. ______________________________. ...
Amount of used material in experiments during the above inventory time period. Does not include stock solution made for later ...
We as Radiologists and Physicians are particularly well clued to the concept of ALARA (as low as reasonably achievable) in terms of Radiation hazards awareness. Whilst investigating children for musculoskeletal ailments this gets translated into a very narrow range of availability of Cross-sectional modalities to arrive at a conclusive diagnosis.
ALA -----Alabama AMW -----ALARA Management Worksheet AEH -----Alarm Event Handler AKJ -----Alaska, Juneau AKI -----Alaskan Independent Party AYX
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CAU 104 comprises the 15 CASs listed below: (1) 07-23-03, Atmospheric Test Site T-7C; (2) 07-23-04, Atmospheric Test Site T7-1; (3) 07-23-05, Atmospheric Test Site; (4) 07-23-06, Atmospheric Test Site T7-5a; (5) 07-23-07, Atmospheric Test Site - Dog (T-S); (6) 07-23-08, Atmospheric Test Site - Baker (T-S); (7) 07-23-09, Atmospheric Test Site - Charlie (T-S); (8) 07-23-10, Atmospheric Test Site - Dixie; (9) 07-23-11, Atmospheric Test Site - Dixie; (10) 07-23-12, Atmospheric Test Site - Charlie (Bus); (11) 07-23-13, Atmospheric Test Site - Baker (Buster); (12) 07-23-14, Atmospheric Test Site - Ruth; (13) 07-23-15, Atmospheric Test Site T7-4; (14) 07-23-16, Atmospheric Test Site B7-b; (15) 07-23-17, Atmospheric Test Site - Climax These sites are being investigated because existing information on the nature and extent of potential contamination is insufficient to evaluate and recommend corrective action alternatives (CAAs). Additional information will be obtained by conducting a corrective action
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Other data set: Additional PCB congeners are reported under data file name PCBPOL_F. Among these PCB congeners PCB 105, 114, 118, 156, 157, 167 and 189 has a toxic equivalence factor (TEF) and may be used with this data set for calculating a total TCDD equivalence.. Subsample Weights. PCDDs, PCDFs, and cPCBs were measured in a one-third subsample of participants 12 years and older. Special sample weights are required to analyze these data properly. Specific sample weights for this subsample are included in this data file and should be used when analyzing these data.. Samples were pooled in groups of 8 samples per pool within 40 demographic groups. The analysis of NHANES 2009-2010 pooled-sample data must be conducted with the basic demographic variables provided in this data file. This pooled-sample data file cannot be linked to other NHANES 2009-2010 data. Because each sample person does not have an equal probability of selection, sample weighting is needed to produce correct population ...
ARSENIC PENTOXIDE | As2O5 | CID 14771 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
A method is provided for removing an implanted cardiac lead having a lead body and at least one conductive electrode from a mammalian body. The method includes the steps of providing an indifferent electrode, establishing electrical contact between the indifferent electrode and the body, and providing a generator of electrical energy. The method further includes the steps of coupling the generator between the conductive electrode and the indifferent electrodes and causing the generator to apply electrical energy between the conductive electrode and the indifferent electrode. The energy has a magnitude sufficient to produce gas by electrolysis between the conductive electrode and fibrotic tissue grown around the electrode. Thereafter, the lead body is pulled in an anterior direction relative to the mammalian body to remove the cardiac lead from the mammalian body.
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von Boetticher H, Lachmund J, Looe HK, Hoffmann W, Poppe B. 2007 Recom¬-mendations of the ICRP change basis for estimation of the effective dose: What is the impact on radiation dose assessment of patient and personnel? Fortschr. Röntgenstr. 180 (2008) 391- ...
https://www.susfert.eu/wp-content/uploads/2019/04/DSC02382-group-photo.jpg 3264 4896 SUSFERT https://www.susfert.eu/wp-content/uploads/2018/05/SUSFERT-WEB-300x61.png SUSFERT2019-04-16 10:30:052019-04-16 10:51:55Third SUSFERT consortium meeting held in Ljubljana, Slovenia ...
Global and Regional High-purity Vanadium Pentoxide Market Research Report 2017 is a market research report available at US $3500 for a Single User PDF License from RnR Market Research Reports Library.
The level of knowledge and the attitude of dentists regarding radiation safety will have a direct impact on patient exposure to radiation. Aim: The aim of the present study was to evaluate the knowledge and attitude of dentists regarding radiation safety in government dental clinics in Khartoum, Sudan. Materials and Methods: A cross-sectional study using an administered structured questionnaire was carried out. The questionnaire consisted of 13 questions that included the demographic data of dentists, basic knowledge regarding radiation safety, knowledge of methods of dose reduction and the attitude of dentists regarding radiation safety. One hundred and sixty seven dental practitioners participated in the study. Results: The response rate was 90%. The majority were female, 59%, in the age group younger than 29 years with clinical experience less than 10 years. Only fifteen of the respondents identified themselves as specialist. Half of the respondents did not know that the thyroid gland is the ...
1. Radiation Safety Orientation Training (Self Study or Group Session) Must be completed by all staff and students within one month of being listed on a Radioisotope Permit at the University of Manitoba. Completing the Orientation exempts staff and students from attending the first morning of the Radiation Safety Workshop for Radioactive Chemicals as listed below. 2. Radiation Safety Workshop for Radioactive Chemicals (1½ Days) This Workshop must be completed by all staff and students within four months of being listed on an open source (radioactive chemicals) radioisotope permit at the University of Manitoba. 3. Radiation Safety Workshop for Nuclear Gauges/Moisture Density Gauges (4 hours) This Workshop must be completed by all staff and students prior to using or transporting a Nuclear Gauge and within four months of being listed on a University Radioisotope Permit for Nuclear Gauges ...
Introduction. Absorbed dose is the most important physical quantity for evaluating potential biological response as a result of exposure to ionizing radiation (IR). Physical dosimetry is commonly performed by instruments that are sensitive to the physical effects of IR. However, in most cases involving real or suspected accidental exposure, people are not wearing a dosimeter and, as a result, physical dosimetry is not straightforward. For such situations, the study of early biological effects induced by an exposure to IR has been proposed as either a complementary or an alternative method for dose assessment (Downing, 2000; Amaral, 2002; Bonassi and Au, 2002; Ramalho and Nascimento, 1991; Ramalho et al., 1995; Voisin et al., 2001).. Biological dosimetry (biodosimetry) is based on the investigation of radioinduced biological effects (bioindicators) in order to correlate them with the radiation dose. Among the bioindicators employed in biodosimetry, the scoring of chromosome aberrations (CA) is ...
Objectives: This study aimed to measure the absorbed doses in selected organs for prospectively ECG-triggered coronary computed tomography angiography (CCTA) using five different generations CT scanners in a female adult anthropomorphic phantom and to estimate the effective dose (HE). Materials and Methods: Prospectively ECG-triggered CCTA was performed using five commercially available CT scanners: 64-detector-row single source CT (SSCT), 2 × 32-detector-row-dual source CT (DSCT), 2 × 64-detector-row DSCT and 320-detector-row SSCT scanners. Absorbed doses were measured in 34 organs using pre-calibrated optically stimulated luminescence dosimeters (OSLDs) placed inside a standard female adult anthropomorphic phantom. HE was calculated from the measured organ doses and compared to the HE derived from the air kerma-length product (PKL) using the conversion coefficient of 0.014 mSv_mGy-1_cm-1 for the chest region. Results: Both breasts and lungs received the highest radiation dose during CCTA ...
Molecular toxicology of polybrominated diphenyl ethers: nuclear hormone receptor mediated pathways.: Polybrominated diphenyl ethers (PBDEs) are used in large qu
Lawrence Island". Body Burden Report. Retrieved 2006-06-12. State of Alaska Epidemiology Bulletin. PCB Blood Test Results from ...
Lawrence Island". Body Burden Report. Retrieved 2006-06-12. State of Alaska Epidemiology Bulletin. PCB Blood Test Results from ...
"What is body burden?". Chemicalbodyburden.org. Retrieved 9 February 2014. "Third National Report on Human Exposure to ... Biomonitoring - measurement of the body burden of toxic chemical compounds, elements, or their metabolites, in biological ... Medical imaging - Play media Medical imaging is the technique and process used to create images of the human body (or parts and ... within the body) molecule which exerts a biochemical and/or physiological effect on the cell, tissue, organ, or organism. More ...
... and social factors influenced children's body burden levels. Eating poultry and pork contributed to elevated body burdens for ... The body burden of PBDEs in Americans correlates well with the level of PBDEs measured in swabs of their hands, likely picked ... In recent years, PBDEs have become widespread environmental pollutants, while body burden in the general population has been ... "Impact of dust from multiple microenvironments and diet on PentaBDE body burden". Environmental Science & Technology. 46 (2): ...
The highest body burdens were found in Western Europe in the 1970s and early 1980s,[2][47][48] and the trends have been similar ... the body burden will increase almost over the whole lifetime. Therefore, the concentrations may increase five- to tenfold from ... This has also led to decreases in human body burdens, which is neatly demonstrated by the decrease of dioxin concentrations in ... where they are then stored in the body. Their half-life in the body is estimated to be 7 to 11 years.[24] ...
ISBN 978-0-7100-6299-4. Scaer, Robert C. (2001). The Body Bears the Burden: Trauma, Dissociation, and Disease. Binghamton, NY: ... Traumatic stress: The effects of overwhelming experience on mind, body, and society. New York: Guilford Press. pp. 303-27. CS1 ...
A series of studies testing for the presence of chemicals in people's bodies is known as body burden. The organization has also ... CDC: Americans Carry Body Burden of Toxic Sunscreen Chemical. Environmental Working Group. EWG, 25 Mar. 2008. Web. 14 Mar. 2014 ...
W.W. Norton & Company, N.Y. & London, 2005 Scaer, Robert C. (2001). The Body Bears the Burden: Trauma, Dissociation, and ... Body psychotherapy Psychosomatic medicine van der Kolk, Bessel (2014). The Body Keeps the Score: Brain, Mind, and Body in the ... In the face of arousal, "discharge" is facilitated to allow the client's body to return to a regulated state. Discharge may be ... and other mental and physical trauma-related health problems by focusing on the client's perceived body sensations (or somatic ...
Scaer, R.C. (2001). The Body Bears the Burden: Trauma, Dissociation, and Disease. New York: The Haworth Press. [1] Jasper ... A classic text in the field is Traumatic Stress, the Effects of Overwhelming Experiences on the Mind, Body and Society. For a ... body, and society. New York, Guilford Press, 214-241. Felitti, V.J., Anda, R.F., Nordenberg, D., Williamson, D.F., Spitz, A.M ... to successfully bond and attach to others has been growing in importance as new information is learned about how the human body ...
... from this analysis overall body burden is inferred.[192] Chelation challenge mainly measures the burden of lead in soft tissues ... Blood lead levels are an indicator mainly of recent or current lead exposure, not of total body burden.[164] Lead in bones can ... Chelation challenge, also known as provocation testing, is used to indicate an elevated and mobilizable body burden of heavy ... this may be the best measure of cumulative exposure and total body burden.[30] However this method is not widely available and ...
Bill West (April 25, 2015). "Bradenton outfielder Barnes burdened by his body". TribLIVE.com. Retrieved February 20, 2016. " ...
A single dose of ivermectin gives a rapid and durable decrease in body burden of eyeworm (Loa loa). The risk of ivermectin- ... However, ivermectin is contraindicated in persons with a high burden of loiasis (e.g., ,20,000 Loa loa microfilariae per mL), ...
Scaer, Robert (2007). The Body Bears the Burden: Trauma, Dissociation, and Disease, Second Edition. Philadelphia, PA: Haworth ...
Garner, Dwight (September 27, 2012). "Growing Up in a Town of Weak Beer and Toxic Water: Book Review: Full Body Burden by ... Iverson, Kristen (2013). Full Body Burden: Growing Up in the Nuclear Shadow of Rocky Flats. Broadway Books. ISBN 0307955656. ...
Maximum permissible body burdens were given for 11 nuclides. At this time it was first stated that the purpose of radiological ... The contents are made available for adoption by national regulatory bodies to the extent that they wish. Early recommendations ... in any 1 week in the case of whole-body exposure to X and gamma radiation at the surface, and 1.5 roentgen (0.013 grays) in any ...
... the average human body burdens of DDT and PCB have been declining. Since their ban in 1972, the PCB body burden is 1/100 of ... Diet is thought to account for up to 90% of a person's PCB and DDT body burden. In a study of 32 different common food products ... Residents living in homes with wood floors treated in the 1960s with PCB-based wood finish have a much higher body burden than ... One study estimated that ingestion of house dust accounts for up to 82% of our PBDE body burden. Research conducted by the ...
Burden survived and even had rope scars on his body two years later. Conahan's credit cards were subpoenaed and his house was ... The star witness was Stanley Burden who had been nearly killed in 1994. Conahan's attorney rebutted that Burden was an ... The body had been outside for about a month and had rope burns on the skin and the genitalia had been removed and discarded. ... Stanley Burden, the star witness at Conahan's trial, had been attacked within a mile of the site where the eight skeletons were ...
"Non-invasive therapy to reduce the body burden of aluminium in Alzheimer's disease". J. Alzheimers Dis. 10 (1): 17-24; ...
Lawrence, J. N. (1962). PUQFUA, an IBM 704 code for computing plutonium body burdens. Health Physics. 8(1): 61-66.. ... Langham, W. H. (1957). Excretion methods: The application of excretion analyses to the determination of body burden of ... Plutonium Body Burden (Q) from Urine Analysis - software program PUQFUA is a computer program written in the FORTRAN language. ...
Unfortunately, this method has its limits in that only a small fraction of Pu is excreted, for example 0.01% of the body burden ... giving him an initial body burden of 3.546 μCi total activity.[8] The fact that he had the highly radioactive Pu-238 (produced ... human tracer experiments began with the intent to determine how to properly analyze excretion samples to estimate body burden. ... Unlike the case of radium, which can be detected quite easily, there are no gamma rays to detect from outside the body. As long ...
... committed to undertake testing of their chemical body burdens. The second forum, the United Nations Champions Body Burden Forum ... Body Burden and 5 Gyres are the first of a series of Safe Planet films. These films contributed to the elevation of awareness ... The first UN Body Burden Forum featured UN Messenger of Peace and Nobel Peace Prize recipient Professor Wangari Maathai and UN ... The United Nations Body Burden Forum has introduced the Campaign's flagship human biomonitoring project. This project exposed ...
Filser JG, Denk B, Törnqvist M, Kessler W, Ehrenberg L (1992). "Pharmacokinetics of ethylene in man; body burden with ethylene ... For the body to generate nitric oxide through the nitrate-nitrite-nitric oxide pathway, the reduction of nitrate to nitrite ... Although the body requires oxygen for metabolism, low oxygen levels normally do not stimulate breathing. Rather, breathing is ... H2S pools in the body attracts oxygen to react with excess H2S and eNOS to increase NO production. With increased use of oxygen ...
As little as 0.03 μCi (1,110 Bq) is the maximum permissible body burden for 241Am. Americium-241 is an α-emitter with a weak γ- ...
... the immunological response of the body. Where the burden of parasites in the body is light, there may be no symptoms. Certain ... Because individuals are predisposed to a high or a low worm burden, the burden reacquired after successful treatment is ... Signs of the body's immune response may include eosinophilia, edema, and arthritis. An example of the immune response is the ... The maximum worm burden is at five to ten years of age, declining rapidly thereafter. Individual predisposition to ...
Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Body Mass Index) (2011). "National, regional, ... The human body contains chemical compounds, such as water, carbohydrates (sugar, starch, and fiber), amino acids (in proteins ... These compounds may be found in the human body as well as in the various types of organisms that humans consume.[medical ... Once absorbed, they cannot be stored in the body, so they are either metabolized as required or excreted in the urine.[medical ...
Children are passed substantial body burdens by their mothers, and breastfeeding increases the child's body burden. Dioxin ... The most sensitive effects are caused at body burdens relatively close to those reported in humans. Among the animals for which ... Breast fed children usually still have higher dioxin body burdens than non breast fed children. The WHO still recommends breast ... The oral LD50 for guinea pigs is as low as 0.5 to 2 μg/Kg body weight, whereas the oral LD50 for hamsters can be as high as 1 ...
... of slightly increasing Democratic representation in legislative bodies, but would also give Utah an additional, probably ... traveling abroad as religious missionaries should be counted as residents and that the failure to do so imposed a burden on ...
Dark with sweat they bear their burden to the very doors, The precious body they bear; While all the village folk, dumbfounded ... In the third part of the poem it is seen how the enemy rebels bring the body of Cosmas into his home village through these ... In particular piety the old Gheg talks about the heroism of Cosmas, therefore swears before the dead body of the hero, that no ... telling the cry that the enemies of the peasants caused by bringing the inanimate body of Cosmas into the village. It is in ...
... and social factors influenced childrens body burden levels. Eating poultry and pork contributed to elevated body burdens for ... The body burden of PBDEs in Americans correlates well with the level of PBDEs measured in swabs of their hands, likely picked ... In recent years, PBDEs have become widespread environmental pollutants, while body burden in the general population has been ... "Impact of dust from multiple microenvironments and diet on PentaBDE body burden". Environmental Science & Technology. 46 (2): ...
Children and people of color typically have the highest "body burdens.". During the public comment period, the Consumer Product ...
This is the human body burden - the pollution in people that permeates everyone in the world, including babies in the womb. ... Substantial scientific evidence demonstrates that children face amplified risks from their body burden of pollution; the ... In light of the findings in this study and a substantial body of supporting science on the toxicity of early life exposures to ...
More and more people are demanding the right to know what chemicals are in their bodies. In California, a bill is being pushed ... Interest in body burden testing, or "biomonitoring", has spiked since the late 1990s, when scientists discovered that a type of ... First of all, its really hard to figure out the pathway of exposure by looking at your body burden levels. You just really ... She hopes a program for broad body burden testing might one day reveal why one in eight women in the United States develops ...
Body Burden. Body Burden. Every one of us carries residue in our bodies from exposures to man-made chemicals - exposures we ... In order to understand what chemicals we are exposed to and what effects they are having in our bodies, the science of bio- ...
The authors conclude that the data support an additive model for the body burden of acetone combined with MEK. ... JOCMA7; NIOSH-Author; Pharmacodynamics; Solvent-vapors; Ketones; Kinetics; Humans; In-vivo-studies; Body-burden; Blood-analysis ... MEK was more rapidly cleared from the body following exposure than was acetone. There was a consistent trend toward lower blood ... http://journals.lww.com/joem/Abstract/1987/29110/Body_Burden_Profiles_of_Single_and_Mixed_Solvent.7.aspx ...
A cow grazing on PCB-laced feed will store the chemical in her body and excrete it in her milk, and humans too act as sinks for ... Ed Browns new movie Unacceptable Levels tells the story of chemicals in our bodies: how they get there, what it means to our ... Bioaccumulation happens when chemicals in food, water, and air end up getting stored in the body of a living thing. Thus, for a ... Last week, researchers found a host of toxic chemicals in the bodies of pregnant women throughout the U.S. Industry reps ...
Body Burden. Every one of us carries residue in our bodies from exposures to man-made chemicals - exposures we never consented ... or body burden studies, is emerging. Senate Bill No. 1379 CHAPTER 599 ... Do you feel called to stand for Future Generations? Do you believe the health of our bodies is intimately tied to the health of ... In order to understand what chemicals we are exposed to and what effects they are having in our bodies, the science of bio- ...
What is Body burden? Meaning of Body burden as a legal term. What does Body burden mean in law? ... Definition of Body burden in the Legal Dictionary - by Free online English dictionary and encyclopedia. ... burden of easeeent, burden of going forward with evidence, burden of loss, burden of persuasion, burden of proof, burden upon ... Body burden legal definition of Body burden https://legal-dictionary.thefreedictionary.com/Body+burden ...
Maternal body burden of organochlorine pesticides and dioxins. This study investigated the body burden of organochlorine ... Most people are unaware that they carry chemical compounds in their bodies. Chemical Body Burden refers to the accumulation ... Biomonitoring: is body burden relevant to public health?. Biomonitoring is the study of the presence and concentration of ... Before birth, people normally carry a body burden inherited from their mothers. Scientists believe the typical human being ...
This is called our "body burden." The pollution is from chemicals getting dumped into our waterways, soil, and air. These ... Environmental Working Groups 2005 Study, "Body Burden-The Pollution in Newborns," found some horrifying results:. "Of the 287 ... "body burden." This series of articles will help you make decisions to reduce the chemicals in your childs blood as they grow ...
The increasing prevalence of excess body weight, which was responsible for approximately 3.9% of all cancers worldwide in 2012 ... Growing prevalence of excess body weight increasing global cancer burden. Sung H, et al. Ca Cancer J Clin. 2018;doi:10.3322/ ... Women have been found to have a higher cancer burden attributable to excess body weight than men (368,500 vs. 175,800 cases). ... Women have been found to have a higher cancer burden attributable to excess body weight than men (368,500 vs. 175,800 cases). ...
Duncan wrote about his body burden in a recent issue of National Geographic, and his report is a fair document of what kinds of ... A few years ago, this internal pollution was given the name Human Body Burden. It is quantified by measuring up to 700 ... David Ewing Duncan is a Bay area-based journalist who has been quantifying his body by getting his genes sequenced and blood ... Ive been researching how to quantify the level of exotic, synthetic chemicals which all our bodies pick up while living in a ...
The Body Burden of Environmental Contaminants in a Vulnerable Population - Addis Ababa, Ethiopia ... Exposure to Polluted Drinking Water: The Body Burden of Environmental Contaminants in a Vulnerable Population - Addis Ababa, ... and 50 community members who lived further from the Akaki River to help assess the body burden and health effects of exposure ...
Modified citrus pectin can help to deep clean the body to reduce body burden of these toxins that can lead to chronic disease, ... Modified Citrus Pectin Helps Reduce Body Burden Of Toxins. 2 months ago ... The brain and body was never designed to eliminate heavy metals and these chemicals from the body, the liver and kidneys cant ... When the body is not able to break down and eliminate these toxins they become stored in far reaches of the liver or in fat ...
Body Burden and other films. Every person alive today carries approximately 250 chemicals within their body, chemicals that ... The world premiere of "Body Burden" is part of the Toronto Environmental Film & Video Festival http://www.planetinfocus.org tel ...
... within a persons body their body burden.. Body burden is just a number - a concentration in parts per billion or micrograms ... When scientists start taking about body burden, I think about real bodies - my own and my childrens. ... body burdens have decreased since they were last measured. Thats great news. It means that the pollution of our bodies, like ... If a lower body burden seems like a sensible, desirable thing, then we are going to need to limit the chemicals to which we ...
The aim of this study was to establish an international cohort of patients with quantified whole-body internal tumor burden and ... "Quantitative Assessment of Whole-Body Tumor Burden in Adult Patients with Neurofibromatosis." Edited by Karl Herholz. PLoS ONE ... Quantitative Assessment of Whole-Body Tumor Burden in Adult Patients with Neurofibromatosis. ... We determined the number, volume, and distribution of internal nerve sheath tumors in patients using whole-body MRI (WBMRI) and ...
CDC Body Burden Study Finds Widespread Pesticide Exposure. July 22, 2005. The Centers for Disease Control and Prevention (CDC) ... A body burden study released last week by the Environmental Working Group (EWG) reported findings similar to the CDC study, ... Sources: CDC National Report on Human Exposure to Environmental Chemicals,http://www.cdc.gov/exposurereport/; Body Burden, The ... Organochlorines are known to persist in the environment, build up in peoples bodies, and are passed from mother to child in ...
"Chemical body burden" researchers and advocates raise questions about biomonitoring studies and hazards regulations. ... "Chemical body burden" researchers and advocates raise questions about biomonitoring studies and hazards regulations. ... WASHINGTON-The catchphrase chemical body burden, or the presence of hazardous chemicals and their residues in humans, has ... Part of the confusion stems from the fact that it is unclear how hazardous chemicals get into homes or the bodies of residents ...
In this instance, a mass of body fat might be 40% of 70 kg, or 28,000 g. Given the same total body burden in two individuals ... A normal body mass index (BMI) of 25 corresponds to a range of 20-25% body fat [27]. Individuals with BMI of 35 may have a body ... When body fat was expressed as percent of body mass, the half-life doubled from approximately 4 to 8 years when percent body ... be related to sequelae of persistent body burdens.. Presumably the fraction of an OC stored in the body that undergoes ...
Urinary Thymidine Dimer as a Marker of Total Body Burden of UV-Inflicted DNA Damage in Humans. Natalia Kotova, Kari Hemminki ... Analysis of such repair products in the urine could serve as a biomarker of total body burden of UV exposure. The aim of this ... If normalized for dose and body surface area, the individual levels varied from 2.0 to 9.3 pmol per J/m2 per m2 body surface ... Urinary Thymidine Dimer as a Marker of Total Body Burden of UV-Inflicted DNA Damage in Humans ...
Teens Cosmetic & Beauty Products Use Results in Body Burden of Toxic Chemicals Says EWG. September 25, 2008 by Jennifer ... The Environmental Working Group released a report yesterday documenting that US teens are carrying a body burden of hormone ... Teens Turning Green has a greener body care product line aimed at teens now available at Whole Foods (coming soon to Los ...
Body burdens, sources and interrelations of selected toxic and essential elements among the nine Cree First Nations of Eeyou ... Body burdens, sources and interrelations of selected toxic and essential elements among the nine Cree First Nations of Eeyou ... composite variables allowed a more detailed understanding of both the sources of the essential and toxic elements in body ...
... ... Keywords: cost analysis, body mass index, disease burden, cardiovascular disease, diabetes, hypertension, obesity ... Allender S, Rayner M. The burden of overweight and obesity-related ill health in the UK. Obes Rev. 2007;8:467-473. [PubMed] ... Optimal body weight for health and longevity: bridging basic, clinical, and population research. Aging cell. 2014;13:391-400. [ ...
  • Last week, researchers found a host of toxic chemicals in the bodies of pregnant women throughout the U.S. Industry reps quickly trotted out their favorite messages in response: "Chemicals are a fact of modern life," "just because toxins are in your body doesn't mean they'll hurt you," and "the levels are too low to matter - researchers have new tools that can measure extremely low levels. (panna.org)
  • It takes time to remove the chemicals and toxins - but it is 'right now' that you can reduce putting garbage into your body. (mthfr.net)
  • Body burden is a popular term used by environmental scientists to describe the total accumulation of toxins in our bodies or pollution in people! (sfbayview.com)
  • These toxic chemicals are your "body burden" - the amount of chemicals, toxins, and other pollutants in your body at any given point. (kangenwell.com)
  • Climate change's propensity to increase the formation of natural toxins and mobilize heavy metals and pollutants have a disproportionate effect on the young because their organs are still developing and because per pound of body weight, children inhale more air, eat more food, and drink more water than adults. (slideshare.net)
  • Climate change increases the burden of toxins our daughters will pass to their children. (slideshare.net)
  • These toxins were found in their mother's body regardless of whether the mother had ever visited a farm or been around pesticides or a chemical/manufacturing plant. (bcaction.org)
  • The 'H' of the F.I.G.H.T program stands for two things - Heavy Metals and Hormones Increasing levels of pollution across the world mean that our bodies have become saturated with toxins like never before. (antiaging-systems.com)
  • First of all, it's really hard to figure out the pathway of exposure by looking at your body burden levels. (loe.org)
  • MEK was more rapidly cleared from the body following exposure than was acetone. (cdc.gov)
  • From June 24-July 7, 2011, the HS team collected questionnaire data, drinking water, urine, and blood samples from 100 community members who lived in close proximity to the Akaki River, and 50 community members who lived further from the Akaki River to help assess the body burden and health effects of exposure to water from the Akaki River among residents of the Akaki-Kaliti sub city. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) yesterday released its Third National Report on Human Exposure to Environmental Chemicals, finding that more than 90% of U.S. residents carry a mixture of pesticides in their bodies. (panna.org)
  • Children, who are particularly vulnerable to the effects of pesticide exposure, had higher levels of some pesticides in their bodies than adults. (panna.org)
  • Although effort is underway to reduce the exposure of people to OCs, this work toward decreasing environmental levels will presumably not produce a significant reduction in the levels in the biosphere in the immediate future and does not address the bioaccumulated burden already present in many individuals. (hindawi.com)
  • Analysis of such repair products in the urine could serve as a biomarker of total body burden of UV exposure. (aacrjournals.org)
  • Some food types were identified to be associated with phthalate body burden and diet might be a source of phthalate exposure among Chinese schoolchildren. (biomedcentral.com)
  • However, in developing countries where higher risk of exposure to foods contaminated by phthalates might exist, studies are still scarce in investigating how dietary intake relates with phthalate body burden in vulnerable group such as children in quantified ways. (biomedcentral.com)
  • Considering the wide range of phthalate contamination in daily food and the higher risk of exposure to phthalates for children compared to for adults, this study intended to assess the phthalate body burden through dietary intake focusing on school-age children in China. (biomedcentral.com)
  • Silver ions (Ag + ) released from AgNPs are supposed to be the major pathway leading to body burden following exposure to test media containing AgNPs. (springer.com)
  • We do have challenges to overcome like rapid urbanization, lack of multisectorial policy making, lack of finance for research and development and lack of monitoring exposure to health burden from air pollution. (springer.com)
  • 1-2 analyte], its metabolite, or another marker of exposure in human body fluids or tissues to confirm human exposure to a hazardous substance [also see exposure investigation]. (cdc.gov)
  • Testing of persons to find out whether a change in a body function might have occurred because of exposure to a hazardous substance. (cdc.gov)
  • The presence of asbestos bodies (ABs) in lung parenchyma is considered a histopathologic hallmark of past exposure to asbestos fibers, of which there was a population of longer fibers. (cdc.gov)
  • Fingernail has been suggested as a biomarker of fluoride (F) body burden , but there is no consensus if it would be a reliable indicator of F exposure from dentifrice . (bvsalud.org)
  • Significant dose-dependent correlations between cumulative exposure to Hg from dental amalgams and urinary porphyrins associated with Hg body-burden (pentacarboxyporphyrin, precoproporphyrin, and coproporphyrin) were observed. (chemweb.com)
  • The global burden is calculated in terms of disability adjusted life years and takes into account mild mental retardation and cardiovascular symptoms due to lead exposure. (medindia.net)
  • The highest burden of lead exposure (99%) occurs in low and middle-income countries. (medindia.net)
  • Once in the body, stored OCs can mobilize from adipose tissue storage sites and, along with circulating OCs, are delivered into the small intestine via hepatic processing and biliary transport. (hindawi.com)
  • Full Body Burden - Growing Up in the Nuclear Shadow of Rocky Flats", the story of the nuclear weapons plant at Rocky Flats, Colorado, is a tale of government and industry denial and cover-up, corporate greed, a public health and environmental contamination scandal. (blogspot.ch)
  • Full Body Burden is Kristen Iversen's story of growing up in a small Colorado town close to Rocky Flats, a secret nuclear weapons plant. (barnesandnoble.com)
  • Interest in body burden testing, or "biomonitoring", has spiked since the late 1990s, when scientists discovered that a type of chemical flame retardants - called PBDES - had rapidly been building up in animals and humans. (loe.org)
  • A cow grazing on PCB-laced feed will store the chemical in her body and excrete it in her milk, and humans too act as sinks for all kinds of chemicals . (panna.org)
  • WASHINGTON-The catchphrase 'chemical body burden,' or the presence of hazardous chemicals and their residues in humans, has started to be teased apart by researchers and environmental health advocates in recent years. (scientificamerican.com)
  • The lower chlorinated congener No. 28 is more readily removed from the body and is predicted to reach an equilibrium concentration in humans. (lancs.ac.uk)
  • It is clear that the interruption of absorption of OCs from the intestinal lumen into the systemic circulation can reduce the accumulation of OCs in the body. (hindawi.com)
  • Accumulation of silver in the animals exposed to the different treatments was apparent, whereby silver ions (Ag + ) released from AgNPs were supposed to be the major pathway leading to body burden. (springer.com)
  • This toxin has no odor or colour and is almost impossible to detect that harms the body slowly and insidiously making one sicker and sicker until it's too late. (worldhealth.net)
  • Our skin is a reflection of our inner health, including but not limited to toxin burden, immune dysfunction, infection, gastrointestinal health, and several nutrient insufficiencies. (ndnr.com)
  • Conventional therapy for eczema treats the specific symptoms and does not take into account the total body burden that may be contributing to its development, nor does it investigate the cause of the eczema in individual patients. (ndnr.com)
  • may contribute to total body burden. (jdsupra.com)
  • These same substances were also found in human milk, placental tissue, umbilical cord blood, and the blood and body fat of newborns. (autism.com)
  • To determine the feasibility of using whole body cardiovascular MRI (WB-CVMR) to compare South Asians (SA) - a population known to have a higher risk of cardiovascular disease (CVD) but paradoxically lower prevalence of peripheral arterial disease (PAD) - and Western Europeans (WE). (dundee.ac.uk)
  • Whole body cardiovascular MRI (WB-CVMR) can quantify cardiac and atheroma burden, and can detect differences in these metrics between ethnic groups that, if validated, may suggest that the paradoxical high risk of CVD compared with PVD risk may be due to an adverse cardiac haemodynamic status incurred by the smaller heart rather than atherosclerosis. (dundee.ac.uk)
  • abstract = "OBJECTIVES: To determine the feasibility of using whole body cardiovascular MRI (WB-CVMR) to compare South Asians (SA) - a population known to have a higher risk of cardiovascular disease (CVD) but paradoxically lower prevalence of peripheral arterial disease (PAD) - and Western Europeans (WE).METHODS: 19 SA and 38 age, gender and BMI matched WE were recruited. (dundee.ac.uk)
  • This is the human 'body burden' - the pollution in people that permeates everyone in the world, including babies in the womb. (ewg.org)
  • Maternal body burden of BDE-153 was inversely associated with first trimester total T3, otherwise no associations between PBDEs and first and second trimester THs were observed. (biomedcentral.com)
  • Ed Brown's new movie Unacceptable Levels tells the story of chemicals in our bodies: how they get there, what it means to our health, how in the world it can be legal, and what we can do about it. (panna.org)
  • Do you believe the health of our bodies is intimately tied to the health of our communities, ecosystems, and our political systems? (sehn.org)
  • The diagnosis and treatment of these common and preventable chronic diseases places a significant burden on National Health Service budgets. (pubmedcentralcanada.ca)
  • However, little is known about the true (non-estimated) impact of body mass index (BMI) on the inpatient and outpatient health care costs for these adiposity-associated chronic diseases. (pubmedcentralcanada.ca)
  • Anthropometric measures, including body weight and standing height, were assessed by trained health workers. (biomedcentral.com)
  • Recent research indicates that all human beings carry varying amounts of chemicals in our bodies, with health effects that are not yet known. (rcsf.ca)
  • In 2003, a network of public health, faith, labor and environmental groups known as the California Body Burden Campaign championed legislation to establish a biomonitoring program. (sfbayview.com)
  • CONCLUSIONS: This study shows the importance of recognising excess body weight as a major risk to health, particularly among females, highlighting the need to develop, implement and evaluate comprehensive interventions to achieve lasting change in the determinants and impact of excess body weight. (uwc.ac.za)
  • National Commission on Macroeconomics and Health, Burden of Diseases in India. (springer.com)
  • A change in body function or the structures of cells that can lead to disease or health problems. (cdc.gov)
  • Accidental or intentional trauma from foreign bodies represents a large chunk of the preventable injury health care burden. (acsh.org)
  • She examines such things as health pamphlets, advertising, medical advice and popular culture, and uses excerpts from the diaries of girls and young women to illustrate changing attitudes toward such issues as menstruation, sexual activity, acne, weight and body shape. (bradley.edu)
  • Her test results are consistent with other studies in the United States and Europe that chart the intrusion of the Industrial Age on the human body. (loe.org)
  • A few years ago, this internal pollution was given the name Human Body Burden. (quantifiedself.com)
  • Body Burden is the total amount of naturally-occurring and man-made chemicals that are present now in the human body. (mthfr.net)
  • Body burden"-also called the internal or absorbed dose-is the amount of chemical compound present in the human body at a given point in time. (rcsf.ca)
  • Thyroid hormones (THs) regulate many biological functions in the human body and are essential for normal brain development. (biomedcentral.com)
  • Thyroid hormones (THs) regulate a wide array of biological functions in the human body, including metabolism and development. (biomedcentral.com)
  • A human body can handle some heavy metals. (medicalnewstoday.com)
  • The amount of radiation to which a member of the general population is exposed from natural sources, such as terrestrial radiation from naturally occurring radionuclides in the soil, cosmic radiation originating from outer space, and naturally occurring radionuclides deposited in the human body. (cdc.gov)
  • The average American home contains 3-10 gallons of hazardous materials, and 85 percent of the chemicals that are registered have never been tested for their impact on the human body. (autism.com)
  • For a person or an animal, absorption is the process of a substance getting into the body through the eyes, skin, stomach, intestines, or lungs. (cdc.gov)
  • When a skin care product is used, it can be absorbed and stored within the body…The question then becomes, how much absorption is too much. (bcaction.org)
  • Doyle: Bill Moyers was one of the folks who picked up on the Centers for Disease Control's body burden issue in the spring of 2001. (thefreedictionary.com)
  • Over the past decade agencies like the Center for Disease Control and Prevention (CDC) have been tracking chemical burden in the general public by analyzing blood and urine. (beyondpesticides.org)
  • Biomonitoring is a research tool that measures levels of chemicals in our bodies by analyzing samples of blood, tissue, urine, hair and breast milk using mass spectrometry. (sfbayview.com)
  • This is particularly problematic in the setting of systemic factors, such as functional disability, performance-based outcomes requiring the use of multiple joint sites, serum/urine biomarkers, and genetics, which are necessarily a reflection of the whole-body burden of OA and the impact of that burden on the individual. (biomedcentral.com)
  • WHO HQ Library catalog › Results of search for 'su:{Body burden. (who.int)
  • The sum of the products of the weighting factors applicable to each of the body organs or tissues that are irradiated and the committed dose equivalent to the organs or tissues integrated over a specified time period (such as 50 or 70 years). (cdc.gov)
  • An immune hypersensitivity reaction of body tissues to allergens that can affect the skin (urticaria), respiratory tract (asthma), gastrointestinal tract (vomiting and nausea) or produce a systemic circulatory response (anaphylactic response). (nih.gov)
  • A condition in which there is reduced or impaired red blood cells or hemoglobin resulting in an inadequate capacity of the blood to transport oxygen to body tissues. (nih.gov)
  • An insufficient (below normal) supply of oxygen in the body tissues. (nih.gov)
  • Our bodies are made up of trillions of cells that form tissues and organs. (cancer.ca)
  • Connective tissue holds parts of the body together and supports other tissues. (cancer.ca)
  • LOBET: Patton's body, it turned out, contained 105 of the 210 metals and synthetic chemicals researchers tested for. (loe.org)
  • The researchers pointed out, however, that economic growth is not necessarily associated with excess body weight. (healio.com)
  • The rapid increase in both the prevalence of excess body weight and the associated cance rburden highlights the need for a rejuvenated focus on identifying, implementing, and evaluating interventions to prevent and control excess body weight," the researchers wrote. (healio.com)
  • Avoiding products which contain EDCs for just three days can help to reduce levels of these harmful chemicals in the body, a new study led by researchers from the University of California, Berkeley has shown. (breastcanceruk.org.uk)
  • Moreover, approximately 3.9% of all cancers (544,300 cases) in 2012 were linked to excess body weight, with percentages varying from less than 1% in low-income countries to 7% or 8% in high-income Western nations and Middle Eastern and North African countries. (healio.com)
  • A report from the International Agency for Research on Cancer Working Group on Body Fatness states that adequate evidence exists to make a causal association between excess body weight and increased risk for 13 cancers. (healio.com)
  • Controlling global rates of obesity is one of nine key initiatives WHO is undertaking to reduce the burden of cancer and other noncommunicable diseases. (healio.com)
  • Any one of a group of diseases that occur when cells in the body become abnormal and grow or multiply out of control. (cdc.gov)
  • In this article we will discuss the burden of these neurodegenerative diseases and Ayurvedic strategies for prevention and treatment. (ayurvedicscience.com)
  • WB-CVMR was performed, comprising a whole body angiogram (WBA) and cardiac MR (CMR), on a 3T MRI scanner following dual phase injection of gadolinium based contrast agent. (dundee.ac.uk)
  • Polymorphisms of genes related to metabolism of lead (Pb) are associated with the metal body burden and with biomarkers of oxidative stress. (cdc.gov)
  • These toxicants are believed to have caused abnormal genetic expression and metabolism in the body that leads to a degenerative process. (ayurvedicscience.com)
  • Taken together, our data indicate that polymorphisms related to Pb toxicokinetics modify the metal body burden and Pb-related antioxidant effects. (cdc.gov)
  • Every one of us carries residue in our bodies from exposures to man-made chemicals - exposures we never consented to. (sehn.org)
  • Body burden profiles of single and mixed solvent exposures. (cdc.gov)
  • A body burden study released last week by the Environmental Working Group (EWG) reported findings similar to the CDC study, focusing specifically on chemical exposures infants received before they were born. (panna.org)
  • A number of studies have used biomonitoring techniques to determine levels of chemicals in the body and concerns have emerged around disclosing results. (rcsf.ca)
  • Our results suggest that maternal PCDD/F and BDE-153 body burdens influence maternal TH status in early pregnancy, which is a critical period when maternal TH status influences fetal development. (biomedcentral.com)
  • A standardized atherosclerotic score (SAS) was calculated from the WBA, while indexed left ventricular mass and volumes were calculated from the CMR.RESULTS: SAs exhibited a significantly lower iliofemoral atheroma burden (regional SAS 0.0±0.0 vs 1.9±6.9, p=0.048) and a trend towards lower overall atheroma burden (WB SAS 0.7±0.8 vs 1.8±2.3, p=0.1). (dundee.ac.uk)
  • RAND's substantial body of work on teacher pay-for-performance provides policymakers with a strong evidence base on the design, implementation, and potential results of pay-for-performance programs. (rand.org)
  • LOBET: As Sharyle Patton sat in a tiny clinic room watching her blood fill yet another vial, she mused that after years as an activist lobbying against persistent chemicals, she would finally learn her own chemical fingerprint -- what had built up in her body over a lifetime. (loe.org)
  • Drawing on personal stories of individuals who have had their chemical body burdens tested, she described how migrant farm workers in California had developed a strong activist community as a result of biomonitoring. (thefreedictionary.com)
  • If you are thinking about having a baby, if you are pregnant, or if you just had a baby, consider taking action to reduce your baby's chemical "body burden. (more.com)
  • Seeping into our body through our food, water, air, and even our medicines, the level of damaging heavy metals present in our body has rocketed in the last cent. (antiaging-systems.com)
  • were a dominant determinant of differentials in total parasite body burden among species and locations. (thefreedictionary.com)