Blood Transfusion: The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)Blood Transfusion, Autologous: Reinfusion of blood or blood products derived from the patient's own circulation. (Dorland, 27th ed)Erythrocyte Transfusion: The transfer of erythrocytes from a donor to a recipient or reinfusion to the donor.Platelet Transfusion: The transfer of blood platelets from a donor to a recipient or reinfusion to the donor.Exchange Transfusion, Whole Blood: Repetitive withdrawal of small amounts of blood and replacement with donor blood until a large proportion of the blood volume has been exchanged. Used in treatment of fetal erythroblastosis, hepatic coma, sickle cell anemia, disseminated intravascular coagulation, septicemia, burns, thrombotic thrombopenic purpura, and fulminant malaria.Blood Component Transfusion: The transfer of blood components such as erythrocytes, leukocytes, platelets, and plasma from a donor to a recipient or back to the donor. This process differs from the procedures undertaken in PLASMAPHERESIS and types of CYTAPHERESIS; (PLATELETPHERESIS and LEUKAPHERESIS) where, following the removal of plasma or the specific cell components, the remainder is transfused back to the donor.Blood Loss, Surgical: Loss of blood during a surgical procedure.Blood Transfusion, Intrauterine: In utero transfusion of BLOOD into the FETUS for the treatment of FETAL DISEASES, such as fetal erythroblastosis (ERYTHROBLASTOSIS, FETAL).Blood Banks: Centers for collecting, characterizing and storing human blood.Blood DonorsBlood Grouping and Crossmatching: Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion.Operative Blood Salvage: Recovery of blood lost from surgical procedures for reuse by the same patient in AUTOLOGOUS BLOOD TRANSFUSIONS. It is collected during (intraoperatively) or after completion of (postoperatively) the surgical procedures.Fetofetal Transfusion: Passage of blood from one fetus to another via an arteriovenous communication or other shunt, in a monozygotic twin pregnancy. It results in anemia in one twin and polycythemia in the other. (Lee et al., Wintrobe's Clinical Hematology, 9th ed, p737-8)Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.Postoperative Hemorrhage: Hemorrhage following any surgical procedure. It may be immediate or delayed and is not restricted to the surgical wound.Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.Hemoglobins: The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.Antifibrinolytic Agents: Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.Intraoperative Care: Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.Jehovah's Witnesses: Members of a religious denomination founded in the United States during the late 19th century in which active evangelism is practiced, the imminent approach of the millennium is preached, and war and organized government authority in matters of conscience are strongly opposed (from American Heritage Dictionary of the English Language, 4th ed). Jehovah's Witnesses generally refuse blood transfusions and other blood-based treatments based on religious belief.Blood Preservation: The process by which blood or its components are kept viable outside of the organism from which they are derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).Blood Group Incompatibility: An antigenic mismatch between donor and recipient blood. Antibodies present in the recipient's serum may be directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984).Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Blood Safety: The degree to which the blood supply for BLOOD TRANSFUSIONS is free of harmful substances or infectious agents, and properly typed and crossmatched (BLOOD GROUPING AND CROSSMATCHING) to insure serological compatibility between BLOOD DONORS and recipients.Anemia, Neonatal: The mildest form of erythroblastosis fetalis in which anemia is the chief manifestation.Leukocyte Transfusion: The transfer of leukocytes from a donor to a recipient or reinfusion to the donor.Hemodilution: Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.Perioperative Care: Interventions to provide care prior to, during, and immediately after surgery.Blood Substitutes: Substances that are used in place of blood, for example, as an alternative to BLOOD TRANSFUSIONS after blood loss to restore BLOOD VOLUME and oxygen-carrying capacity to the blood circulation, or to perfuse isolated organs.Plateletpheresis: The preparation of platelet concentrates with the return of red cells and platelet-poor plasma to the donor.beta-Thalassemia: A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.Erythroblastosis, Fetal: A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.Isoantibodies: Antibodies from an individual that react with ISOANTIGENS of another individual of the same species.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Hemostatics: Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure.Erythropoietin: Glycoprotein hormone, secreted chiefly by the KIDNEY in the adult and the LIVER in the FETUS, that acts on erythroid stem cells of the BONE MARROW to stimulate proliferation and differentiation.Leukocyte Reduction Procedures: The removal of LEUKOCYTES from BLOOD to reduce BLOOD TRANSFUSION reactions and lower the chance of transmitting VIRUSES. This may be performed by FILTRATION or by CYTAPHERESIS.Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.Hemorrhage: Bleeding or escape of blood from a vessel.Hemostasis, Surgical: Control of bleeding during or after surgery.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Preoperative Care: Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)Red Cross: International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Fetomaternal Transfusion: Transplacental passage of fetal blood into the circulation of the maternal organism. (Dorland, 27th ed)Surgical Procedures, Elective: Surgery which could be postponed or not done at all without danger to the patient. Elective surgery includes procedures to correct non-life-threatening medical problems as well as to alleviate conditions causing psychological stress or other potential risk to patients, e.g., cosmetic or contraceptive surgery.Blood-Borne Pathogens: Infectious organisms in the BLOOD, of which the predominant medical interest is their contamination of blood-soiled linens, towels, gowns, BANDAGES, other items from individuals in risk categories, NEEDLES and other sharp objects, MEDICAL WASTE and DENTAL WASTE, all of which health workers are exposed to. This concept is differentiated from the clinical conditions of BACTEREMIA; VIREMIA; and FUNGEMIA where the organism is present in the blood of a patient as the result of a natural infectious process.Cardiopulmonary Bypass: Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.Postoperative Care: The period of care beginning when the patient is removed from surgery and aimed at meeting the patient's psychological and physical needs directly after surgery. (From Dictionary of Health Services Management, 2d ed)Hepatitis C: INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally, and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.Rh Isoimmunization: The process by which fetal Rh+ erythrocytes enter the circulation of an Rh- mother, causing her to produce IMMUNOGLOBULIN G antibodies, which can cross the placenta and destroy the erythrocytes of Rh+ fetuses. Rh isoimmunization can also be caused by BLOOD TRANSFUSION with mismatched blood.Hematinics: Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.Aprotinin: A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)Arthroplasty, Replacement, Knee: Replacement of the knee joint.Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)Length of Stay: The period of confinement of a patient to a hospital or other health facility.Chelation Therapy: Therapy of heavy metal poisoning using agents which sequester the metal from organs or tissues and bind it firmly within the ring structure of a new compound which can be eliminated from the body.Cardiac Surgical Procedures: Surgery performed on the heart.Postpartum Hemorrhage: Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).Infant, Newborn: An infant during the first month after birth.Plasma: The residual portion of BLOOD that is left after removal of BLOOD CELLS by CENTRIFUGATION without prior BLOOD COAGULATION.Platelet Count: The number of PLATELETS per unit volume in a sample of venous BLOOD.Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.Thrombocytopenia: A subnormal level of BLOOD PLATELETS.Hepatitis C Antibodies: Antibodies to the HEPATITIS C ANTIGENS including antibodies to envelope, core, and non-structural proteins.Blood Coagulation Disorders: Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.Surgical Procedures, Operative: Operations carried out for the correction of deformities and defects, repair of injuries, and diagnosis and cure of certain diseases. (Taber, 18th ed.)Phlebotomy: The techniques used to draw blood from a vein for diagnostic purposes or for treatment of certain blood disorders such as erythrocytosis, hemochromatosis, polycythemia vera, and porphyria cutanea tarda.Hepatectomy: Excision of all or part of the liver. (Dorland, 28th ed)Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Reticulocyte Count: The number of RETICULOCYTES per unit volume of BLOOD. The values are expressed as a percentage of the ERYTHROCYTE COUNT or in the form of an index ("corrected reticulocyte index"), which attempts to account for the number of circulating erythrocytes.Hematocrit: The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Hepatitis, Viral, Human: INFLAMMATION of the LIVER in humans due to infection by VIRUSES. There are several significant types of human viral hepatitis with infection caused by enteric-transmission (HEPATITIS A; HEPATITIS E) or blood transfusion (HEPATITIS B; HEPATITIS C; and HEPATITIS D).Arthroplasty, Replacement, Hip: Replacement of the hip joint.Creutzfeldt-Jakob Syndrome: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))Peptic Ulcer Hemorrhage: Bleeding from a PEPTIC ULCER that can be located in any segment of the GASTROINTESTINAL TRACT.Seroepidemiologic Studies: EPIDEMIOLOGIC STUDIES based on the detection through serological testing of characteristic change in the serum level of specific ANTIBODIES. Latent subclinical infections and carrier states can thus be detected in addition to clinically overt cases.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Tattooing: The indelible marking of TISSUES, primarily SKIN, by pricking it with NEEDLES to imbed various COLORING AGENTS. Tattooing of the CORNEA is done to colorize LEUKOMA spots.Rh-Hr Blood-Group System: Erythrocyte isoantigens of the Rh (Rhesus) blood group system, the most complex of all human blood groups. The major antigen Rh or D is the most common cause of erythroblastosis fetalis.Iron Chelating Agents: Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems.Christianity: The religion stemming from the life, teachings, and death of Jesus Christ: the religion that believes in God as the Father Almighty who works redemptively through the Holy Spirit for men's salvation and that affirms Jesus Christ as Lord and Savior who proclaimed to man the gospel of salvation. (From Webster, 3d ed)Intraoperative Period: The period during a surgical operation.Fetoscopy: Endoscopic examination, therapy or surgery of the fetus and amniotic cavity through abdominal or uterine entry.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Intraoperative Complications: Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.Hepatitis B: INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Epistaxis: Bleeding from the nose.Drainage: The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.Blood Group Antigens: Sets of cell surface antigens located on BLOOD CELLS. They are usually membrane GLYCOPROTEINS or GLYCOLIPIDS that are antigenically distinguished by their carbohydrate moieties.Isotonic Solutions: Solutions having the same osmotic pressure as blood serum, or another solution with which they are compared. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)Infant, Premature: A human infant born before 37 weeks of GESTATION.Colonialism: The aggregate of various economic, political, and social policies by which an imperial power maintains or extends its control over other areas or peoples. It includes the practice of or belief in acquiring and retaining colonies. The emphasis is less on its identity as an ideological political system than on its designation in a period of history. (Webster, 3d ed; from Dr. J. Cassedy, NLM History of Medicine Division)Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.Erythrocyte Count: The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD.Plasma Substitutes: Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.Anemia, Hemolytic, Autoimmune: Acquired hemolytic anemia due to the presence of AUTOANTIBODIES which agglutinate or lyse the patient's own RED BLOOD CELLS.Coombs Test: A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.Thrombelastography: Use of a thrombelastograph, which provides a continuous graphic record of the physical shape of a clot during fibrin formation and subsequent lysis.Erythrocytes: Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.Hemosiderosis: Conditions in which there is a generalized increase in the iron stores of body tissues, particularly of liver and the MONONUCLEAR PHAGOCYTE SYSTEM, without demonstrable tissue damage. The name refers to the presence of stainable iron in the tissue in the form of hemosiderin.Hospital Mortality: A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).ABO Blood-Group System: The major human blood type system which depends on the presence or absence of two antigens A and B. Type O occurs when neither A nor B is present and AB when both are present. A and B are genetic factors that determine the presence of enzymes for the synthesis of certain glycoproteins mainly in the red cell membrane.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.Transplantation, Homologous: Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals.Nephrostomy, Percutaneous: The insertion of a catheter through the skin and body wall into the kidney pelvis, mainly to provide urine drainage where the ureter is not functional. It is used also to remove or dissolve renal calculi and to diagnose ureteral obstruction.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Erythrocyte Aging: The senescence of RED BLOOD CELLS. Lacking the organelles that make protein synthesis possible, the mature erythrocyte is incapable of self-repair, reproduction, and carrying out certain functions performed by other cells. This limits the average life span of an erythrocyte to 120 days.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Perioperative Period: The time periods immediately before, during and following a surgical operation.Trauma Centers: Specialized hospital facilities which provide diagnostic and therapeutic services for trauma patients.Antisickling Agents: Agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle cell conditions.Vacuum: A space in which the pressure is far below atmospheric pressure so that the remaining gases do not affect processes being carried on in the space.Blood Cell Count: The number of LEUKOCYTES and ERYTHROCYTES per unit volume in a sample of venous BLOOD. A complete blood count (CBC) also includes measurement of the HEMOGLOBIN; HEMATOCRIT; and ERYTHROCYTE INDICES.Hemoglobinometry: Measurement of hemoglobin concentration in blood.Patient Identification Systems: Organized procedures for establishing patient identity, including use of bracelets, etc.Fibrin Tissue Adhesive: An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.Laparoscopy: A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.Shock, Hemorrhagic: Acute hemorrhage or excessive fluid loss resulting in HYPOVOLEMIA.Medical Audit: A detailed review and evaluation of selected clinical records by qualified professional personnel for evaluating quality of medical care.Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.Splenectomy: Surgical procedure involving either partial or entire removal of the spleen.Jaundice, Neonatal: Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.Papilloma, Inverted: A mucosal tumor of the urinary bladder or nasal cavity in which proliferating epithelium is invaginated beneath the surface and is more smoothly rounded than in other papillomas. (Stedman, 25th ed)Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.Blood Specimen Collection: The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Angiodysplasia: Acquired degenerative dilation or expansion (ectasia) of normal BLOOD VESSELS, often associated with aging. They are isolated, tortuous, thin-walled vessels and sources of bleeding. They occur most often in mucosal capillaries of the GASTROINTESTINAL TRACT leading to GASTROINTESTINAL HEMORRHAGE and ANEMIA.Babesia microti: A species of protozoa infecting humans via the intermediate tick vector IXODES scapularis. The other hosts are the mouse PEROMYSCUS leucopus and meadow vole MICROTUS pennsylvanicus, which are fed on by the tick. Other primates can be experimentally infected with Babesia microti.Blood Volume: Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.Critical Illness: A disease or state in which death is possible or imminent.Iron Compounds: Organic and inorganic compounds that contain iron as an integral part of the molecule.Filtration: A process of separating particulate matter from a fluid, such as air or a liquid, by passing the fluid carrier through a medium that will not pass the particulates. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Resuscitation: The restoration to life or consciousness of one apparently dead. (Dorland, 27th ed)Iron: A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.Graft Survival: The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.Otorhinolaryngologic Surgical Procedures: Surgery performed on the ear and its parts, the nose and nasal cavity, or the throat, including surgery of the adenoids, tonsils, pharynx, and trachea.Melena: The black, tarry, foul-smelling FECES that contain degraded blood.Disease Transmission, Infectious: The transmission of infectious disease or pathogens. When transmission is within the same species, the mode can be horizontal or vertical (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).Renal Dialysis: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.Blood Coagulation Tests: Laboratory tests for evaluating the individual's clotting mechanism.Nigeria: A republic in western Africa, south of NIGER between BENIN and CAMEROON. Its capital is Abuja.Military Medicine: The practice of medicine as applied to special circumstances associated with military operations.Flaviviridae: A family of RNA viruses, many of which cause disease in humans and domestic animals. There are three genera FLAVIVIRUS; PESTIVIRUS; and HEPACIVIRUS, as well as several unassigned species.Hemostatic Techniques: Techniques for controlling bleeding.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).Hepacivirus: A genus of FLAVIVIRIDAE causing parenterally-transmitted HEPATITIS C which is associated with transfusions and drug abuse. Hepatitis C virus is the type species.Kell Blood-Group System: Multiple erythrocytic antigens that comprise at least three pairs of alternates and amorphs, determined by one complex gene or possibly several genes at closely linked loci. The system is important in transfusion reactions. Its expression involves the X-chromosome.Micropore Filters: A membrane or barrier with micrometer sized pores used for separation purification processes.Clinical Protocols: Precise and detailed plans for the study of a medical or biomedical problem and/or plans for a regimen of therapy.Infant, Premature, DiseasesStatistics, Nonparametric: A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)Blood Platelets: Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.Kidney Transplantation: The transference of a kidney from one human or animal to another.Injury Severity Score: An anatomic severity scale based on the Abbreviated Injury Scale (AIS) and developed specifically to score multiple traumatic injuries. It has been used as a predictor of mortality.Hepatitis B Surface Antigens: Those hepatitis B antigens found on the surface of the Dane particle and on the 20 nm spherical and tubular particles. Several subspecificities of the surface antigen are known. These were formerly called the Australia antigen.Isoantigens: Antigens that exist in alternative (allelic) forms in a single species. When an isoantigen is encountered by species members who lack it, an immune response is induced. Typical isoantigens are the BLOOD GROUP ANTIGENS.Coronary Artery Bypass: Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.Hepatitis Antibodies: Immunoglobulins raised by any form of viral hepatitis; some of these antibodies are used to diagnose the specific kind of hepatitis.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Intensive Care: Advanced and highly specialized care provided to medical or surgical patients whose conditions are life-threatening and require comprehensive care and constant monitoring. It is usually administered in specially equipped units of a health care facility.Abbreviations as Topic: Shortened forms of written words or phrases used for brevity.Wounds, Nonpenetrating: Injuries caused by impact with a blunt object where there is no penetration of the skin.Priapism: A prolonged painful erection that may lasts hours and is not associated with sexual activity. It is seen in patients with SICKLE CELL ANEMIA, advanced malignancy, spinal trauma; and certain drug treatments.Multiple Trauma: Multiple physical insults or injuries occurring simultaneously.Multiple Organ Failure: A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.Ferritins: Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their major function is to store IRON in a nontoxic bioavailable form. Each ferritin molecule consists of ferric iron in a hollow protein shell (APOFERRITINS) made of 24 subunits of various sequences depending on the species and tissue types.Hospitals, University: Hospitals maintained by a university for the teaching of medical students, postgraduate training programs, and clinical research.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Babesiosis: A group of tick-borne diseases of mammals including ZOONOSES in humans. They are caused by protozoa of the genus BABESIA, which parasitize erythrocytes, producing hemolysis. In the U.S., the organism's natural host is mice and transmission is by the deer tick IXODES SCAPULARIS.Histocompatibility Testing: Identification of the major histocompatibility antigens of transplant DONORS and potential recipients, usually by serological tests. Donor and recipient pairs should be of identical ABO blood group, and in addition should be matched as closely as possible for HISTOCOMPATIBILITY ANTIGENS in order to minimize the likelihood of allograft rejection. (King, Dictionary of Genetics, 4th ed)Critical Care: Health care provided to a critically ill patient during a medical emergency or crisis.Liver Neoplasms: Tumors or cancer of the LIVER.HLA Antigens: Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.Hydroxyethyl Starch Derivatives: Starches that have been chemically modified so that a percentage of OH groups are substituted with 2-hydroxyethyl ether groups.Hemoperitoneum: Accumulations of blood in the PERITONEAL CAVITY due to internal HEMORRHAGE.Postoperative Period: The period following a surgical operation.

Intrauterine management of fetal parvovirus B19 infection. (1/64)

OBJECTIVES: The aim of our study was to determine the outcome of pregnancies after intrauterine management of fetal parvovirus B19 infection. DESIGN: Retrospective study. SUBJECTS: A total of 37 cases of maternofetal parvovirus B19 infection, 35 of which were associated with hydrops fetalis, were referred to our tertiary level center between 1989 and 1996. With regard to fetal hydrops, no apparent cause other than parvovirus B19 infection was found in any patient. METHODS: In all patients, cordocentesis was performed to assess the degree of fetal anemia. When anemia was present, cordocentesis was followed by intrauterine transfusion with packed red cells into the umbilical vein. Further management depended on the degree of fetal anemia and gestational age and included follow-up fetal blood sampling/transfusion as well as ultrasound examinations as deemed appropriate. RESULTS: Packed red cell transfusion was performed in 30 patients with significant fetal anemia (Z-score 1.6-7.8 below the mean for gestational age). The fetal hemoglobin values ranged from 2.1 to 9.6 g/dl. Serum levels of platelets in the transfusion group were 9-228 x 10(9)/l with Z-scores in the range of < 1 to 3.8 below the mean. During treatment and follow-up, there were five intrauterine deaths (13.5%), one neonatal death (2.7%) and 31 live births (83.8%). CONCLUSIONS: Fetal parvovirus infection can lead to marked anemia and hydrops formation. Cordocentesis allows precise assessment of fetal anemia which can then be corrected by intravenous transfusion. Under this regimen, the outcome proved favorable in the majority of fetuses, even those that were severely anemic.  (+info)

Cardiac changes in fetuses secondary to immune hemolytic anemia and their relation to hemoglobin and catecholamine concentrations in fetal blood. (2/64)

OBJECTIVES: Immune hemolytic anemia in the fetus may cause cardiac decompensation and intrauterine death. Postnatally, norepinephrine (noradrenaline) is released in chronic heart failure, and may lead to myocardial hypertrophy. The aim of this study was to determine fetal cardiac changes associated with immune hemolytic anemia by means of echocardiography, and to relate them to fetal hemoglobin and norepinephrine levels. DESIGN: Thirty anemic fetuses underwent a total of 76 umbilical venous transfusions. Before the procedure, fetal echocardiography was performed, and end-diastolic myocardial wall thicknesses and ventricular dimensions together with Doppler flow patterns at the atrioventricular and semilunar valves were measured. Fetal hemoglobin, epinephrine and norepinephrine concentrations were determined before the transfusion. Statistical analysis of this prospective study comprised descriptive statistics including linear regression and correlation analyses. Two samples of measurements were compared by the Mann-Whitney U test. RESULTS: The mean hemoglobin concentration before the first transfusion was 6.9 g% at a mean gestational age of 26.8 weeks. Norepinephrine values were elevated in comparison to a reference range, and were higher than epinephrine values. The most striking echocardiographic finding was myocardial hypertrophy of all ventricular walls. Mean blood flow velocities were increased; at the left ventricle, they were negatively related to the hemoglobin concentrations, and positively to the norepinephrine values. CONCLUSIONS: Fetal myocardial hypertrophy in anemia may be the result of an augmented cardiac workload, indicated by the increased left ventricular mean velocities. This reaction reflects the redistribution of blood flow that may depend on hemoglobin and norepinephrine concentrations.  (+info)

Perinatal management of fetal hemolytic disease due to Rh incompatibility combined with fetal alloimmune thrombocytopenia due to HPA-5b incompatibility. (3/64)

We report out experience in the perinatal management of a complex case of fetal hemolytic disease primarily due to Rhesus incompatibility combined with fetal alloimmune thrombocytopenia. The lowest fetal hemoglobin and platelet levels were 2.6 g/dl and 13,000/microliter, respectively. Intrauterine treatment consisted of six transfusions of packed red cells into the umbilical vein and one transfusion of platelets. The neonate required four transfusions of packed red cells to correct her hyporegenerative erythropoiesis. Postnatal management also included one platelet transfusion, intravenous immunoglobulins and erythropoietin. Although some degree of fetal thrombocytopenia may invariably be found in fetal red cell incompatibility, other rare causes need to be excluded.  (+info)

Pathophysiology and treatment of fetal anemia due to placental chorioangioma. (4/64)

Placental chorioangiomas occur in 1% of pregnancies. Large chorioangiomas may cause serious complications such as fetal anemia, hydrops and fetal death. In this case report, a pregnancy complicated by a large placental chorioangioma is described. Severe fetal anemia without the occurrence of hydrops fetalis was suspected using ultrasound and Doppler examinations. Successful intrauterine blood transfusion was performed, with an unusually large amount of blood needed to obtain an adequate rise in fetal hematocrit. Two weeks later, at 32 weeks, the infant was born in good condition. In pregnancies with large chorioangiomas, we advise regular ultrasound and Doppler examinations, with the aim of detecting fetal anemia before hydrops develops. When anemia is suspected, fetal blood sampling is indicated and intrauterine transfusion therapy may be beneficial to preserve fetal health until maturity is reached.  (+info)

Survival of donor cells 25 years after intrauterine transfusion. (5/64)

Persistence of donor leukocytes in the circulation of recipients of intrauterine transfusion (IUT) has been observed up to 5 years after birth. The aim of this study was to determine whether transfusions with nonirradiated, nonleukocyte-depleted donor blood during the fetal period resulted in long-term immunomodulation of the recipient. Twenty-four surviving IUT recipients between 1966 and 1976 were tested for autoimmune disease and autoantibodies at follow-up. Ten had sex-mismatched donors and were therefore informative for chimerism studies using fluorescence in situ hybridization (FISH). Seven female recipients could be tested for chimerism using a Y- chromosome-specific polymerase chain reaction (PCR) because they received at least 1 IUT from a male donor. Nine recipients could be studied for cytotoxic T-lymphocyte precursor (CTLp) and helper T-lymphocyte precursor (HTLp) frequencies because the original donors were available for testing. All surviving IUT recipients were in good health at the time of the examination, and routine laboratory testing revealed no abnormalities. None of the IUT recipients were chimeric as determined by FISH analysis, but Y-chromosome-specific sequences were detected by PCR in 6 of the 7 women. However, the CTLp and HTLp frequencies of the IUT recipients against the donors were comparable to those of the controls. The current study provides evidence that IUT can result in the persistence of donor cells in the recipient for a period longer than 20 years but that it is not associated with immunotolerance or with signs of chronic antigenic stimulation. (Blood. 2000;95:2709-2714)  (+info)

Dual natriuretic peptide response to volume load in the fetal circulation. (6/64)

OBJECTIVE: To measure atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in control fetuses and fetuses with Rhesus isoimmunisation before and after intravascular transfusion. The current study was designed to investigate the response of ANP and BNP to cardiac short-term and long-term volume load in the human fetus. METHODS: Fetal blood samples were collected from 18 human fetuses (nine controls, nine anemic fetuses with Rhesus isoimmunisation before and after intravascular transfusion). Fetal ANP and BNP concentrations were measured and compared to maternal plasma levels. RESULTS: Both ANP and BNP were significantly higher in fetal blood compared to the mothers. Fetuses with Rhesus isoimmunisation, characterized by long-term cardiac overload, showed significantly elevated ANP but not BNP concentration compared to the fetal controls (ANP: 80.8+/-16.6 vs. 31.6+/-7.7 pg/ml, P<0.05). However, short-term volume load due to intravascular transfusion leads to a significant increase in the fetal BNP- but not ANP-plasma level (BNP: 112.9+/-14.1 vs. 64.8+/-6.6 pg/ml, P<0.05). CONCLUSION: ANP and BNP respond differently to cardiac short- and long-term volume load in the fetal circulation. Therefore, the data suggest that in the fetus, similar to adults, ANP and BNP constitute a dual natriuretic peptide system responsive to changes in cardiac filling pressure.  (+info)

Hydrops fetalis-associated congenital dyserythropoietic anemia treated with intrauterine transfusions and bone marrow transplantation. (7/64)

Hydrops fetalis is rarely caused by congenital dyserythropoietic anemia (CDA). We report a patient with hydrops fetalis as a result of severe anemia. This patient needed intrauterine transfusions from 21 weeks of gestation until birth. The hematologic study showed an atypical CDA (hydrops fetalis-associated CDA) characterized by features resembling CDA type II, but negative acidified serum lysis test (HEMPAS negative). The patient was regularly transfused for a year, after which an allogeneic bone marrow transplantation (BMT) from an HLA-identical sibling was successfully carried out. His actual hemoglobin is 127 g/L, and he has not received transfusions for more than a year. In conclusion, intrauterine transfusions and BMT could cure an otherwise lethal atypical CDA.  (+info)

Management of single fetal death in twin-to-twin transfusion syndrome: a role for fetal blood sampling. (8/64)

OBJECTIVE: Intrauterine death of one twin in monochorionic pregnancies is associated with an increased mortality and morbidity of the cotwin. This is likely to occur as a consequence of acute hemodynamic changes due to feto-fetal hemorrhage at the time of death of the cotwin. We assessed the role of fetal blood sampling and intrauterine transfusion to rescue the survivor. MATERIALS AND METHODS: We managed 12 cases of single intrauterine death at between 17 and 26 weeks' gestation in monochorionic twins complicated by twin-to-twin transfusion syndrome (TTTS). All these cases had been treated either by laser therapy or by serial amniodrainage. When the demise of one twin occurred, ultrasound-guided fetal blood sampling was performed in the surviving twin using a 20-gauge needle within 24 h of death. Intrauterine transfusion was performed at the same time in cases where the survivor was anemic. All survivors were assessed in the neonatal period and at 1 year of age. RESULTS: Six of the 12 surviving fetuses were found to be anemic and underwent intrauterine transfusion. All fetuses survived the procedure. Four of these fetuses had normal neurological development at 1 year of age. Periventricular leukomalacia developed in one case and the patient underwent termination of pregnancy at 34 weeks. In one case delivery occurred at 34 weeks' gestation and the baby developed periventricular leukomalacia at 1 month of age. In all six non-anemic fetuses pediatric examination was normal at birth and at 1 year of age. CONCLUSION: Intrauterine death of one monochorionic twin in TTTS puts the survivor at high risk of intrauterine death or of developing ischemic/hypoxic lesions. Our results suggest that fetal blood sampling is a useful diagnostic tool to identify those fetuses that are not anemic and hence unlikely to be at risk of developing a cerebral lesion.  (+info)

PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Rh incompatibility occurs when a pregnant woman whose blood type is Rh-negative is exposed to Rh-positive blood from her fetus, leading to the mother s development of Rh antibodies. These antibodies have the potential to cross the placenta and attach to fetal red blood cells, resulting in hemolysis, or destruction of the fetus s red blood cells. This causes the fetus to become anemic, which can lead to hemolytic disease of the newborn. In severe cases, an intrauterine blood transfusion for the fetus may be required to correct the anemia.. Format: Articles Subject: Processes, Disorders, Reproduction ...
Rh incompatibility occurs when a pregnant woman whose blood type is Rh-negative is exposed to Rh-positive blood from her fetus, leading to the mother s development of Rh antibodies. These antibodies have the potential to cross the placenta and attach to fetal red blood cells, resulting in hemolysis, or destruction of the fetus s red blood cells. This causes the fetus to become anemic, which can lead to hemolytic disease of the newborn. In severe cases, an intrauterine blood transfusion for the fetus may be required to correct the anemia.. Format: Articles Subject: Processes, Disorders, Reproduction ...
Involved in this field since last 16 years at Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi. He has worked and developed the fetal medicine with Prof. Deepika Deka , at All India Institute of Medical Sciences, New Delhi. He has developed expertise in intrauterine blood transfusions, chorionic villous sampling, amniocentesis and fetal reduction in cases of multiple pregnancies ...
NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used. To access online sources, copy and paste the URL into your browser.. Sources Used in Current Review. (October 14, 2013) Tholpady A. Antibody Screening, Medscape Reference. Available online at http://emedicine.medscape.com/article/1731232-overview#a1. Accessed September 2016.. Henrys Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. McPherson R, Pincus M, eds. Philadelphia, PA: Saunders Elsevier: 2011, 719-730, 741.. Angela Treml MD, Karen E. King MD. Red blood cell alloimmunization: lessons from sickle cell disease. Transfusion 2013;53:692-695.. (July 20, 2016) Sandler G. Transfusion Reactions. Medscape Reference. ...
Eight Rh-sensitized fetuses, between 21 weeks 2 days and 35 weeks of gestation, received 31 intravascular transfusions (13 exchange and 18 bolus) and one intraperitoneal transfusion under ultrasonographic guidance. The interval between transfusions w
Park City, Utah, Jan. 26, 1901.To the Editor:-In your editorial, Dec. 29, 1900, on Treatment of Tuberculosis, you remark that Dr. R. McGuire has lately treate
The use of maternal premedication for IUT varies by center and may include use of local anesthetics, indomethacin/pethidine/promethazine, or spinal epidural analgesia. The prophylactic use of antibiotics or corticosteroids are sometimes used but their necessity is not well-established 18, 19. Premedication for the fetus is necessary in most cases including atracurium or vecuronium 6, 21 for fetal paralysis. Some practitioners recommend fentanyl for fetal pain 20 though it is not universally used 22. Click here for more detailed information about medications during IUTs.. Intrauterine transfusion should be guided by continuous ultrasound and staffed, at minimum, by an experienced maternal fetal medicine (MFM) specialist/perinatologist, seasoned ultrasonographer and one or more operating nurses. Inclusion of a neonatologist and/or additional MFM/perinatologist and support staff is not unwarranted. Transfusion volume can be calculated using a simplified formula by Giannina et al29 to attain 45% ...
This is done before donating blood or having a blood transfusion, to check what your blood group is.. If you were given blood that didnt match your blood group, your immune system may attack the red blood cells, which could lead to potentially life-threatening complications.. Blood typing is also used during pregnancy, as theres a small risk the unborn child may have a different blood group from their mother, which could lead to the mothers immune system attacking her babys red blood cells. This is known as rhesus disease.. If you dont already know your blood type, your blood will be tested at least once during your pregnancy to determine if theres a risk of rhesus disease. Read more about diagnosing rhesus disease.. If testing reveals there is a risk of rhesus disease, an injection of a medicine that stops the mothers immune system attacking her babys blood cells can be given. Read more about preventing rhesus disease.. Read more about blood typing on Lab Tests Online UK.. ...
This is done before donating blood or having a blood transfusion, to check what your blood group is.. If you were given blood that didnt match your blood group, your immune system may attack the red blood cells, which could lead to potentially life-threatening complications.. Blood typing is also used during pregnancy, as theres a small risk the unborn child may have a different blood group from their mother, which could lead to the mothers immune system attacking her babys red blood cells. This is known as rhesus disease.. If you dont already know your blood type, your blood will be tested at least once during your pregnancy to determine if theres a risk of rhesus disease. Read more about diagnosing rhesus disease.. If testing reveals there is a risk of rhesus disease, an injection of a medicine that stops the mothers immune system attacking her babys blood cells can be given. Read more about preventing rhesus disease.. Read more about blood typing on Lab Tests Online UK. ...
This is done before donating blood or having a blood transfusion, to check what your blood group is.. If you were given blood that didnt match your blood group, your immune system may attack the red blood cells, which could lead to potentially life-threatening complications.. Blood typing is also used during pregnancy, as theres a small risk the unborn child may have a different blood group from their mother, which could lead to the mothers immune system attacking her babys red blood cells. This is known as rhesus disease.. If you dont already know your blood type, your blood will be tested at least once during your pregnancy to determine if theres a risk of rhesus disease. Read more about diagnosing rhesus disease.. If testing reveals there is a risk of rhesus disease, an injection of a medicine that stops the mothers immune system attacking her babys blood cells can be given. Read more about preventing rhesus disease.. Read more about blood typing on Lab Tests Online UK.. ...
This is done before donating blood or having a blood transfusion, to check what your blood group is.. If you were given blood that didnt match your blood group, your immune system may attack the red blood cells, which could lead to potentially life-threatening complications.. Blood typing is also used during pregnancy, as theres a small risk the unborn child may have a different blood group from their mother, which could lead to the mothers immune system attacking her babys red blood cells. This is known as rhesus disease.. If you dont already know your blood type, your blood will be tested at least once during your pregnancy to determine if theres a risk of rhesus disease. Read more about diagnosing rhesus disease.. If testing reveals there is a risk of rhesus disease, an injection of a medicine that stops the mothers immune system attacking her babys blood cells can be given. Read more about preventing rhesus disease.. Read more about blood typing on Lab Tests Online UK.. ...
Rhesus disease only affects the baby, and the mother wont experience any symptoms. Around 50% of babies have mild symptoms that are easily treatable.
I took him in for what I thought was a bladder infection, instead at 1:00pm we were loaded in the car on our way to Western Veterinary Specialist Centre in Calgary so he could get blood transfusions.. He has what they think is Immune Mediated Hemolytic Anemia. His own immune system is destroying his red blood cells. Not sure of the cause, the chest x-ray and abdominal scan came back clean so no cancer, he did not eat onions, garlic or Tylenol, not tick season.....no answers and its driving me crazy. After his first transfusion his red cell count is up but he is still sad and threw up a few times last night.. I have never prayed so much in my whole life and hoping that at some point I have done something right to help make this go well and for him to get better. There is a 50/50 chance for recovery, I want so badly for him to be the one out of the two dogs that makes it.. I wish I did not care so much, I wish I had talked myself out of getting him when I saw him that day, I wish I was not raised ...
I took him in for what I thought was a bladder infection, instead at 1:00pm we were loaded in the car on our way to Western Veterinary Specialist Centre in Calgary so he could get blood transfusions.. He has what they think is Immune Mediated Hemolytic Anemia. His own immune system is destroying his red blood cells. Not sure of the cause, the chest x-ray and abdominal scan came back clean so no cancer, he did not eat onions, garlic or Tylenol, not tick season.....no answers and its driving me crazy. After his first transfusion his red cell count is up but he is still sad and threw up a few times last night.. I have never prayed so much in my whole life and hoping that at some point I have done something right to help make this go well and for him to get better. There is a 50/50 chance for recovery, I want so badly for him to be the one out of the two dogs that makes it.. I wish I did not care so much, I wish I had talked myself out of getting him when I saw him that day, I wish I was not raised ...
Tomorrow I go for round 2 of blood work to make sure my HCG levels are doubling every 48-72 hours like they should be. I am quite nervous as it was the second set of blood work back in November that we found out that our pregnancy wasnt viable. Needless to say I am scared to death. CNY called me this morning and said that they collaborated with my Immunologist and decided it was best to start me on specialized blood transfusions called IvIg. The infusions take anywhere from 2-4 hours and I have to have them every 28 days. I was happy to find out that my insurance has agreed to pay for them in full as they are extremely expensive. My first transfusion is Thursday morning. I will post another update tomorrow once I know the results of my blood work ...
Rhesus isoimmunisation information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis.
Lotus launched the first-generation Elise back in 1996 in some markets, and at the time its extruded and bonded aluminum chassis was on the cutting edge. It weighed very little, contributing to the cars 1,600-lb curb weight, but proved race-car strong and highly adaptable. Lightweight technology has moved on these days, and so has Lotus. The company is now...
Intravenous transfusion of concanavalin A-activated splenic cells from acutely diabetic BB or diabetic BB/hooded hybrid donor rats into 6- to 36-h-old neonate recipients of diabetes-prone and -resistant rat lines induced insulitis and in some severe diabetes. These effects were observed 10-20 days after the injection of the blasts. Focal lesions of insulitis were absent in neonates killed 1 and 3 days after the blast injection but were observed in neonates killed on the 5th and 8th day. As determined by autoradiography after the injection of [3H]thymidine-labeled blasts, numerous blast cells migrated and settled in various immature lymph nodes and in the spleen within 24 h after injection. Focal mononuclear infiltrations in the islets containing labeled and unlabeled cells were again observed on the 5th and 8th day but not on the 1st and 3rd day after injection. These experiments indicate that target-specific blasts undergo a short phase of proliferation and maturation in lymphoid organs of the
To I Want My Life Back: I too had bad side effects from the ivermectin! Not the first or second time but this last time, I did suffer-still am! It gave me a horrible neck pain and shoulder cramps-it drove me insane and went to emergency at 11:00 pm! They were no help. Gave me I dose of Perm, no refills and 6 percocets I did not want. I also have a severe red rash from it. No matter what I use they do not kills these bastards. I spray, I vacuum , I scrub, and steam with no results. I think I also have a bacterial infection on top of this rash. Im HIV+ and thats the excuse the doctors use. Im going to a different hospital and see what they suggest. The fungus topical did not work, so Im positive its a rash from those pills. My neck was stiff for a week. I think I need a IV. My legs are swollen too. Im a mess. I did not no ivermectin came in injectabls! Where did u get that? You didnt get a stiff neck? And when I see ppl bathing in borex, do they mean the borex you wash clothes in? Does it ...
Objectives: 1) To determine risk factors for fetomaternal hemorrhage. 2) To identify a cost-effective method to detect fetomaternal hemorrhage prior to significant fetal anemia.. Significance/Background: Fetomaternal hemorrhage (FMH) is a condition in which occurs when the placenta transfers blood from the fetus to the mother. Normally, nutrition and gasses pass from mother to baby through the placenta and only waste products pass from baby to mother through the placenta. Whole blood cells do not normally cross the placenta in significant amounts. Mild FMH, where a small amount of whole blood passes from fetus to mother but does not hurt the mother or baby, occurs in about 75% of pregnancies. A pregnant woman does not know this occurs. It is only discovered if a special blood test that is labor-intensive to perform and difficult to interpret called the Kleihauer-Betke acid elution test is done. As mild FMH hurts no one, this test is not part of routine care. In most cases, testing is done only ...
Transient myeloproliferative disorder and non-immune hydrops fetalis in a neonate with trisomy 21" (February 2014;20:78.e3-4). On page 78.e3 (3rd paragraph, lines 6-8), the sentence should have read "Rhesus isoimmunisation is the commonest immune aetiology, and alpha-thalassaemia is a non-immune cause." rather than "Rhesus isoimmunisation is the commonest immune aetiology, and beta-thalassaemia is the commonest non-immune cause." as printed. We regret the error. The article is correct at www.hkmj.org ...
A 36-week 3550 g neonate is admitted to the intensive care unit and commenced on intensive phototherapy for known Rhesus haemolytic disease. In spite of intensive phototherapy, the bilirubin level approaches the exchange transfusion threshold by hour 16 of life. The specialist registrar orders a crossmatch of blood and arranges for central line insertion in preparation for an exchange transfusion. The new registrar queries why intravenous immunoglobulin is not being used first in an attempt to avoid exchange transfusion. ...
I have anemia and needed a blood transfusion and attempted my first transfusion last week. After about a tablespoon of blood went into my IV, my vision grayed out and I dont remember what happened next. I was told I had chills, diaphoresis, decreased level of consciousness, eyes rolling back in head and woke up so to speak, vomiting. What happened to me? They said I had no fever but had a severe transfusion reaction. I received Benadryl and Solu-Medrol and a bag of fluid after that. They had stopped the blood when I came to and said my blood pressure had dropped to 70/40 and my pulse had dropped. My family doctor was called and diagnosed it as a vasovagal reaction. Can a severe blood transfusion reaction be called a vasovagal reaction? They said there was no hemolyzation of the blood. What exactly happened? How often does this happen? They gave me another unit with the premedication and filter, and it seemed to work okay that time. What do I need to understand about what happened ...
Fetal blood sampling is a procedure to remove a small amount of blood from the fetus during pregnancy. In the past, fetal blood sampling was used only during labor through the mothers open cervix to test blood from the fetal scalp for oxygenation. Today, in many perinatal care centers, fetal blood sampling is performed by specially trained perinatologists as part of diagnosing, treating, and monitoring fetal problems at various times during pregnancy. A fetal blood sample may be taken to:. ...
Fetal blood sampling is a procedure to remove a small amount of blood from the fetus during pregnancy. In the past, fetal blood sampling was used only during labor through the mothers open cervix to test blood from the fetal scalp for oxygenation. Today, in many perinatal care centers, fetal blood sampling is performed by specially trained perinatologists as part of diagnosing, treating, and monitoring fetal problems at various times during pregnancy. A fetal blood sample may be taken to:. ...
... is a procedure to take a small amount of blood from an unborn baby (fetus) during pregnancy. Fetal blood sampling is usually done by a perinatologist with special training. This is a doctor who specializes in the care of babies in high-risk pregnancies.
If you just found out youre pregnant, one of the first tests you should expect is a blood-type test. This basic test determines your blood type and Rh factor, which may play an important role in your babys health.
Used in large fetomaternal haemorrhage (FMH), or for inadvertent or emergency transfusion of Rh (D) positive blood to an Rh (D) negative female of childbearing potential ...
1 \![Kg for the.election, "of U.: S. ena.r I erice railroads on the people by inciting JtiJdcllruow and L .,. j i -iut"c thc 20ih of .JlI\lIan, I$.jti.* at still. The loi leaves k liUI2fru..thl.of :ome of l.uttht the or- There will Int foasul. ali} ia our l.irjje tt >.k. a full l.ne ofGentlemens" S ...
Looking for online definition of Rh incompatibility in the Medical Dictionary? Rh incompatibility explanation free. What is Rh incompatibility? Meaning of Rh incompatibility medical term. What does Rh incompatibility mean?
TY - JOUR. T1 - Fetal platelet counts correlate with the severity of the anemia in red-cell alloimmunization. AU - Saade, George. AU - Moise, K. J.. AU - Copel, J. A.. AU - Belfort, M. A.. AU - Carpenter, R. J.. PY - 1993. Y1 - 1993. N2 - Objective: To determine whether fetal anemia secondary to maternal red-cell alloimmunization is associated with thrombocytopenia. Methods: The records of 78 patients undergoing intrauterine transfusion for red-cell alloimmunization were reviewed. Pre-transfusion fetal platelet counts were compared between hydropic and nonhydropic fetuses. A regression analysis was performed between the fetal platelet counts and the fetal bilirubin levels, hematocrits, and reticulocyte counts taken at the initial transfusion. The hematocrits, reticulocyte counts, and bilirubin levels were adjusted for gestational age by calculating the number of standard deviations (SDs) from the mean for that age or the multiples of the mean (MOM). Student t test, Pearson coefficient, and ...
Diamond Blackfan anemia (DBA) is a lineage-selective inherited bone marrow failure syndrome characterized primarily by anemia and physical malformations. Recent advances in identifying the genetic abnormalities underlying DBA have demonstrated involvement of genes encoding both large (RPL) and small (RPS) ribosomal subunit proteins, including mutations of RPL5, RPL11, RPL35A, RPS7, RPS10, RPS17, RPS19, RPS24, and RPS26 in 50% to 60% of affected patients. Despite significant progress, identification of gene abnormalities in the remaining patients remains an important question since present data suggest that mutations in other members of the ribosomal protein gene complement do not explain those cases without an identified genetic lesion in these genes. Genetic studies have also raised new questions with the recognition of substantial variability in the manifestations of DBA, ranging from ribosomal protein mutations in otherwise asymptomatic individuals to those with classic severe red blood cell ...
Rh incompatibility is caused by destruction of fetal erythrocytes from transplacental passage of maternally derived IgG antibodies. IgG antibodies are produced by the maternal immune system, usually against the rhesus D (RhD) antigen. These antibodies can freely cross the placenta, binding to and destroying RBCs. More than 50 known RBC antibodies potentially cause Rh incompatibility. The consequence is progressive fetal anaemia, which may ultimately lead to hydrops fetalis (collection of fluid in serous compartments) and death. [1] Hadley AG. In vitro assays to predict the severity of hemolytic disease of the newborn. Transfus Med Rev. 1995;9:302-313. http://www.ncbi.nlm.nih.gov/pubmed/8541713?tool=bestpractice.com [2] Bromilow IM, Downing I, Walkinshaw SA, et al. A case of unexplained mild Rh (D) haemolytic disease in utero. Transfus Med. 1995;5:31-35. http://www.ncbi.nlm.nih.gov/pubmed/7767395?tool=bestpractice.com [3] Brennand J, Cameron A. Fetal anaemia: diagnosis and management. Best Pract ...
MDGuidelines is the most trusted source of disability guidelines, disability durations, and return to work information on rh incompatibility.
The line was derived from normal lung tissue from a child who died of erythroblastosis (Rh incompatibility). A normal skin line derived from the same patient is available as ATCC CRL-1497.
The current obstetrical practice at birth in the United States is that the umbilical cord of the infant is clamped immediately. When immediate clamping occurs,...
A rhesus D positive baby in a rhesus D negative mother can cause her circulation to produce anti-D IgG antibodies (isoimmunisation) if foetal cells leak into the maternal circulation which may happen at delivery and in trauma even mild in severity. Tests for D antibodies are done in all Rh-ve mothers at booking, 28 and 34 weeks gestation. Anti-D immunoglobulin is routinely given antenatally at 28 weeks and 34 weeks. Rhesus haemolytic disease is a disease that can vary in severity from mild anaemia to hydrops fetalis or still birth. The Rhesus D antigen has been found to be well established in a 6week old foetus [Murphy] and although the foetus at that age is protected to a large extent by the pelvis the chance of foetal blood leaking into the maternal circulation in the event of an abdominal trauma is highly likely and may infact occur before the standard administration at 28 weeks. Once antibody formation has occurred the administration of anti-D is ineffective so any delay in administering it ...
Looking for Hemolytic disease? Find out information about Hemolytic disease. a disease manifested at birth or shortly thereafter and generally caused by incompatibility of the mothers blood with that of the fetus with respect to the... Explanation of Hemolytic disease
Individuals that become immunized to red blood cell (RBC) alloantigens can experience an increased rate of antibody formation to additional RBC alloantigens following subsequent transfusion. Despite this, how an immune response to one RBC immunogen may impact subsequent alloimmunization to a completely different RBC alloantigen remains unknown. Our studies demonstrate that Kell blood group antigen (KEL) RBC transfusion in the presence of inflammation induced by poly (I:C) (PIC) not only enhances anti-KEL antibody production through a CD4+ T-cell-dependent process but also directly facilitates anti-HOD antibody formation following subsequent exposure to the disparate HOD (hen egg lysozyme, ovalbumin, fused to human blood group antigen Duffy b) antigen ...
Given the delivery of an RhD+ fetus from an RhD-mother, one (1) vial of RhD (300 µg vial administered IM) is recommended when the amount of RhD required is,300 µg. From 300-600 µg, 2 vials are recommended; from 600-900 µg, 3 vials are recommended; from 900-1200 µg, 4 vials are recommended; from 1200-1500 µg, 5 vials are recommended and so forth ...
An article on cordocentesis: what fetal blood sampling involves, when its performed and what the risks and benefits are. Also includes information on the costs of cordocentesis.
... (HDN) used to be a major cause of fetal loss and death among newborn babies. The first descrip
O36.8293 is a billable code used to specify a medical diagnosis of fetal anemia and thrombocytopenia, unspecified trimester, fetus 3. Code valid for the year 2020
Effects of erythrocytapheresis transfusion on the viscoelasticity of sickle cell blood.: Red blood cells containing hemoglobin S are less deformable than normal
RH factor is a protein on some peoples red blood cells. RH disease, or RH incompatibility, occurs when an RH-negative mother is pregnant with an RH-positive baby. Learn how RH disease affects your baby and how to prevent it.
Troudi A., Addouche SA., Dellagi S., El Mhamedi. A, "Logistics Support Approach for Drone Delivery Fleet." In: Alba E., Chicano F., Luque G. (eds) Smart Cities. Smart-CT, 2017. Lecture Notes in Computer Science, vol 10268. 2017 .Springer, Cham. doi: 10.1007/978-3-319-59513-9_9.Print ISBN 978-3-319-59512-2 .Online ISBN 978-3-319- ...
We heard at the radio about two children dead because of a chicken Virus. We would like more scientific informations about this issue. If you know some information, or articles please write to me. François Vial at the IUT of Lyon, France ...
Management of Fetal Arrhythmies The persistents major ipo or ipercinetic arrhythmies could constitute a condition of cardiological fetal emergency and if not in relief and promptly takes care of could conduct the fetus to heart failure and intrauterine death .The worse prognosis when the arrhythmy joins congenital
Cases of CD36 deficiency are not rare in Asian populations, foetal and neonatal alloimmune thrombocytopenia (FNAIT) caused by anti-CD36 isoantibodies appears more frequent than other HPA...
Percent change from baseline in total serum bilirubin (TSB) (the baseline TSB is the TSB that qualifies for randomization) at 48 hours post- ...
... is a blood problem in newborns. It occurs when your babys red blood cells break down at a fast rate. Its also called erythroblastosis fetalis.
Anti-D and anti-c are the two commonest antibodies that contribute to serious haemolytic disease of the foetus and neonate (HDFN). Current practice in the UK is to monitor these antibodies by CFA quantification, which is considered more reproducible and less subjective than manual titration by tube IAT (indirect antiglobulin test). CAT is widely used in transfusion laboratory practice and provides a more objective endpoint than tube technique. ...
Immune hydrops fetalis is most often a complication of a severe form of Rh incompatibility, which can be prevented. This is a condition in which mother who has Rh negative blood type makes antibodies to her babys Rh positive blood cells, and the antibodies cross the placenta ...
Anti-D injections are offered to all pregnant woman who have a rhesus-negative (RhD-negative) blood group to prevent the possibility of the blood disorder RhD haemolytic disease of the newborn. Please note: there is a newer article about Anti-D injections (click here to view). Understanding the medical terms and the details of this disorder and its…. ...
Hydrops fetalis is a serious condition of the fetus or newborn. It is a condition where abnormal amounts of fluid build up in two or more body areas causing swelling. Severe swelling can interfere with how the body organs work and often results in death of the infant shortly before or after delivery.. ...
A case report is a detailed description of disease occurrence in a single person. Unusual features of the case may suggest a new hypothesis about the causes or mechanisms of disease.. Example: Acquired Immunodeficiency in an Infant; Possible Transmission by Means of Blood Products. Link to article by Ammann AJ et al: Acquired immunodeficiency in an infant: possible transmission by means of blood products. The Lancet 1:956-958, 1983.. In April 1983 it had not yet been shown that AIDS could be transmitted by blood or blood products. An infant born with Rh incompatibility; required blood products from 18 donors over 8 weeks and subsequently developed unusual recurrent infections with opportunistic agents such as Candida. The infants T cell count was low, suggesting AIDS. There was no family history of immunodeficiency, but one of the blood donors was found to have died of AIDS. This led the investigators to hypothesize that AIDS could be transmitted by blood transfusion.. Example: Survival after ...
A. Rh incompatibility: Rh antigens from the babys blood enter the maternal bloodstream. The mothers blood does not contain Rh factor, so she produces anti-Rh antibodies. These antibodies are harmless to the mother but attach to the erythrocytes in the fetus and cause hemolysis. Exchange of fetal and maternal blood takes place primarily when the placenta separates at birth.. ...
In commemoration of the Lenten Season, Id like to share one of my Lenten experiences. This happened last year though. I received a call of referral to attend to the delivery of a baby who was initially diagnosed as a case of hydrops fetalis (baby is swollen all over his body). Hydrops fetalis (not the…
Looking for online definition of hemolytic disease of the newborn in the Medical Dictionary? hemolytic disease of the newborn explanation free. What is hemolytic disease of the newborn? Meaning of hemolytic disease of the newborn medical term. What does hemolytic disease of the newborn mean?
Define fetomaternal transfusion. fetomaternal transfusion synonyms, fetomaternal transfusion pronunciation, fetomaternal transfusion translation, English dictionary definition of fetomaternal transfusion. n. 1. The act or process of transfusing. 2. Medicine The transfer of whole blood or blood products from one individual to another. trans·fu′sion·al adj.
Rh immune-globulin acts like a vaccine. It prevents the mothers body from making any Rh antibodies that could cause serious health problems in the newborn or affect a future pregnancy.. A woman also might get a dose of Rh immune-globulin if she has a miscarriage, an amniocentesis, or any bleeding during pregnancy.. If a doctor finds that a woman has already developed Rh antibodies, her pregnancy will be closely watched to make sure that those levels are not too high.. In rare cases, if the incompatibility is severe and a baby is in danger, the baby can get special blood transfusions called exchange transfusions either before birth (intrauterine fetal transfusions) or after delivery. Exchange transfusions replace the babys blood with blood with Rh-negative blood cells. This stabilizes the level of red blood cells and minimizes damage from Rh antibodies already in the babys bloodstream.. Thanks to the success rate of Rh immune-globulin shots, exchange transfusions in Rh-incompatible pregnancies ...
1. ACOG - American College of Obstetricians and Gynecologists. ACOG Practise Bulletin No 75: management of alloimmunization. Obstet Gynecol, 2006, 108, p. 457-464. 2. Ahaded, A. Brossard, Y., Debbia, M., Lambin, P. Quantitative determination of anti-K (KELL 1) IgG and IgG subclasses in the serum of severely alloimmunized pregnant women by ELISA. Transfusion, 2000, 40, p. 239-1245. 3. Alves de Lima, LM., Berthier, ME., Sad, WE., et al. Characterization of an anti-Dia antibody causing hemolytic disease in a newborn infant. Transfusion, 1982, 22, p. 246-247. 4. Avent, ND. The Rhesus blood group systém: insights from recent advances in molecular biology. Transfus Med Rev, 1999, 13, p. 245-266. 5. Avent, N., Finning, K., Martin, P., Soothill, P. Prenatal determination of fetal blood group status. Vox Sang, 2000, 78 (Suppl. 2), p. 155-162. 6. Babinszki, A., Berkowitz, RL. Haemolytic disease of the newborn caused by anti-c, anti-E and anti-Fya antibodies: report of five cases. Prenat Diagn, 1999, 19, ...
Rh negative women who deliver an Rh positive baby are at risk of developing anti-Rh antibodies.1 Rh positive babies born of these mothers will develop Rh haemolytic disease. This is a severe condition responsible for death in utero or in the neonatal period or severe jaundice with ensuing brain damage. The natural history of the disease has not been described in recent literature. Walker,1 in 1971, reviewed a series of cases from his community. It was found that 14% of affected pregnancies resulted in stillbirths. Of the survivors, 30% had severe disease almost certainly fatal without treatment, while an additional 30% had moderate disease which would manifest as severe hyperbilirubinaemia that untreated may result in brain damage and/or death. Forty per cent of cases would require no treatment. Therefore, it can be estimated that approximately 50% of children with untreated haemolytic disease of the newborn (HDN) will die of the disease or develop brain damage. Similar observations were made in ...
Erythroblastosis fetalis occurs due to Rh incompatibility between the mother and the fetus, resulting in severe anemia and sometimes death of the fetus.
Learn about alternatives to blood transfusion on June 24 and June 26. A new nonprofit is bringing seminars on alternatives to blood transfusions to the Peninsula. The group, Hampton Roads Health
... is a medical treatment to replace blood or portions of the blood lost through injury, surgery, or disease.. During a transfusion, people normally receive only the parts of blood needed to treat their conditions. Whole blood is now rarely given as a transfusion.. Blood for transfusions may come from anonymous donors, or a person can bank his or her own blood in preparation for surgery.. ...
Free, official coding info for 2018 ICD-10-CM O36.8293 - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.
S. Emin et H. Nekka [r sum ,article]. La plasmonique Terahertz et optique: composants passifs et actifs - T. Akalin, E. Peytavit, G. Ducournau et J.-F. Lampin [r sum ,article]. Accroissement de labsorption lumineuse au sein de cellules solaires couches minces de silicium par addition de nanoparticules m ...
V J INDUSTRIES - Manufacturer,Supplier and Exporter of Blood Transfusion Set at reasonable prices. Inquire us for best quality Blood Transfusion Set. We export worldwide.
Buy and download royalty-free image ID 4571769: Blood transfusion abstract allegory concept. Transfusion juice from orange to mandarin. Isolated on white. ..
During the next ten years, the transfusion diagnostics market will undergo significant transformation, which will result from the convergence of several
Heart-surgery patients who get transfusions of blood that has been stored for more than 14 days do worse than those who get newer blood, a new study shows. In-h
Nipocalimab, an anti-FcRn antibody, in women who are currently pregnant and have had a prior pregnancy with hemolytic disease of the fetus and newborn (HDFN).. Learn more. ...
See patients profiles of Rh hemolytic disease of the newborn and who should receive with HyperRHO® S/D Prevention in your practice
Immune Hemolytic Anemia White cells May be elevated due to an increased in neutrophils Counts may approach 30 X 109 /L Platelets Usually normal Red cells Hb and Hct decreased Normocytic, normochromic anemia Reticulocytes increased Increased MCV is due to prominent reticulocytosis Spherocytes Bone marrow Hypercellular with erythroid precursors Peripheral Smear ...
Often transfusions are prescribed when simple and safe alternative treatments might be equally effective. As a result such a transfusion may not be necessary. An unnecessary transfusion exposes patients to the risk of infections such as HIV and hepatitis and adverse transfusion reactions.. ...
Free, official coding info for 2018 ICD-10-CM O36.8230 - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.
Watch the video lecture Fetal Hemolytic Disease and prepare for your medical exams with high-yield content ✓ & quiz questions ✓ now!
Title: MedicineNet Blood Transfusion Specialty, Description: MedicineNet Blood Transfusion Specialty, By: Feedage Forager, ID: 331107, Grade: 88, Type: RSS20
The issue of prevention of sensitization during pregnancy - a very important but not yet solved the problem. Designate the first month, 20 mg of prednisone per day and 3 ml intramuscular gamma globulin. In the following months of prednisone dose is 20 mg per day, and non-specific gamma globulin is administered at 3 ml a day.
In non-trauma cases, the decision to transfuse is usually made jointly between the patient and the physician. A recent survey-based study from one US hospital found that both patients (N=294) and physicians (N=73) assume different risks regarding transfusions. Twenty percent of the patients and almost 40% of the physicians surveyed considered transfusions as "very often […]. [Read More] ...
Tutorials in Transfusion Science Continuing Education course- The Michener Institute for health care professionals to learn a variety of transfusion topics
This guideline covers the assessment for and management of blood transfusions in adults, young people and children over 1 year old.
Because blood transfusions carry risks and because the blood supply is limited, doctors try not to transfuse when possible. Here are some alternatives that might be used.
Compatibility testing is the major process which separates the transfusion of red blood cells from the administration of other types of pharmaceutical products
Researchers have developed a new approach to restore nitric oxide (NO) to donated blood, which may help dramatically reduce harmful effects from transfusions.
A number of adverse effects of blood transfusion persist. One is the recent recognition that adverse effects increase with time of storage of packed red cells (...
Statistical red flags undermine a study that questions the safety of men receiving blood transfusions from women who have been pregnant.
Statistical red flags undermine a study that questions the safety of men receiving blood transfusions from women who have been pregnant.
Thank you for submitting an event to our calendar. The event will not appear on the site until a moderator has approved it.. Add another event here.. View the events calendar here.. ...
A page for describing Recap: Simpsons S 2 E 22 Blood Feud. Episode - 7F22 First Aired - 7/11/1991 Mr. Burns is in dire need of a blood transfusion, and Bart …
The laboratory and clinical management of alloimmunized in pregnancy has been investigated according to a protocol currently in use in Örebro region. A 12 year epidemiological study showed the prevalence of alloimmunization to be 0.57% in this Swedish populationwith a 0.24% incidence of clinically significant antibodies that can induce haemolytic disease of the newborn (HDN). Rh antibodies, predominantly anti-D, are still the causes of most cases of severe HDN in which 45/47 babies required exchange transfusion. During the studyperiod, 14 mothers were successfully treated with plasma exchange during pregnancy owing to high anti-D antibody concentrations. Only two other blood group syswms, Kell and Duffy, besides Rh affected newborns to alloimmunized mothers to such a grade that exchange transfusion of the newborns was necessary. All generally accepted for the fetus clinically nonsignificant antibodies were also followed and shown not to cause HDN. In 3 instances, anti-D was detected in partial ...
Background: Despite the minimally invasive nature of trans-catheter aortic valve implantation (TAVI), the procedure is associated with several complications. We analyzed the individual impact of bleeding events, hemoglobin (Hb) drop, and Red Blood Cells (RBC) transfusions on prognosis.. Methods and results: Consecutive patients (n=597) undergoing trans-femoral TAVI were prospectively enrolled. Peri-procedural Hb levels, RBC transfusions and major/life threatening bleeding events were documented and analyzed. To study the relationship between Hb drop, RBC transfusions and long-term mortality, the entire cohort was divided into 4 groups according to Hb drop (less or ≥ than 3 g/dl), and receiving RBC transfusion (yes /no). In the entire cohort mean Hb level decreased following TAVI (11.8±1.4 to 9.5 ±1.3 g/dl; p,0.001). Major/ life threatening bleedings occurred in 66 (10.1%) patients, and 179 (30%) patients received RBC transfusions. Major/life threatening bleedings were not independently ...
In hemolytic disease of the newborn, fetal red cells become coated with IgG alloantibody of maternal origin, directed against an antigen on the fetal cells that is of paternal origin and absent on maternal cells. The IgG-coated cells undergo accelerated destruction, both before and after birth. The clinical severity of the disease can vary from intrauterine death to hematological abnormalities detected only if blood from an apparently healthy infant is subject to serologic testing.. Pregnancy causes immunization when fetal red cells possessing a paternal antigen foreign to the mother enter the maternal circulation, an event described as fetomaternal hemorrhage (FMH). FMH occurs in up to 75% of pregnancies, usually during the third trimester and immediately after delivery. Delivery is the most common immunizing event, but fetal red cells can also enter the mothers circulation after amniocentesis, spontaneous or induced abortion, chorionic villus sampling, cordocentesis, or rupture of an ectopic ...
More scientific information:. There is minimal evidence that administering Rh immune globulin for first trimester vaginal bleeding prevents maternal sensitization or development of hemolytic disease of the newborn. The practice of administering Rh immune globulin to Rh-negative women with a first trimester spontaneous abortion is based on expert opinion and extrapolation from experience with fetomaternal hemorrhage in late pregnancy. Its use for first trimester bleeding is not evidence-based.62, 107 ...
A study was made of A-B-O blood group incompatibility in a series of non-White infants with haemolytic disease of the newborn over a 1-year period.
Each person falls under one of the four blood types, A, B, AB or O, and has either a positive or negative Rh factor which determines their blood cells characteristics. If a person is Rh positive, it means that they are carriers of the Rh factor protein, and those who are Rh negative are non-carriers. Rh disease occurs when the mothers blood type is incompatible with that of her baby, and even though Rh incompatibility doesnt usually pose a problem during the first pregnancy, if the mothers and babys blood intermingle during labor the mothers body will register the babys Rh protein as a foreign substance and will attempt to destroy it by producing antibodies, which could critically threaten the babys wellbeing. That is why an Rh status blood test is usually conducted after the 28th week of pregnancy to check for antibodies and determine whether you need to be given an Rh-immune globulin injection if you are Rh negative. ...
MESCO SURGICAL - Exporter, Manufacturer & Supplier of Blood Transfusion Set Blood Transfusion Set,Blood Administration Set, India
... of blood components are often necessary for the patient to complete the planned cancer treatment.. Blood transfusions are appropriate for low hemoglobin (Hb) and thrombocyte transfusions for low thrombocytes (trc) which also poses a risk for serious bleeding.. ...
Interventional ultrasonography involves biopsy, emptying fluids, intrauterine Blood transfusion (Hemolytic disease of the ... to see from inside blood vessels out through the surrounding blood column, visualizing the endothelium (inner wall) of blood ... A blood flow study is done prior to the injection, by power doppler. The blood flow can be destroyed and the node become ... Power doppler visualized blood flow can be eradicated, and there may be a drop in the cancer blood marker test, thyroglobulin, ...
Liley successfully carried out the first ever successful intrauterine blood transfusion. The fetus had Rh disease/hemolytic ...
... of Twin Anemia-Polycythemia Sequence Using Intrauterine Blood Transfusion for the Donor and Partial Exchange Transfusion for ... Twin anemia-polycythemia sequence, abbreviated as TAPS, is a form of chronic inter-twin transfusion. Different stages of TAPS ... Herway, C.; Johnson, A.; Moise, K.; Moise, K. J. (2009-05-01). "Fetal intraperitoneal transfusion for iatrogenic twin anemia- ... of Feto-fetal Transfusion Flow Through Placental Arterio-venous Anastomoses in a Unique Case of Twin-to-Twin Transfusion ...
The US outbreak identified additional transmission methods through blood transfusion, organ transplant, intrauterine exposure, ... Scottish National Blood Transfusion Service. "West Nile virus". Mayo Clinic. Archived from the original on 26 October 2017. ... Rarely the virus is spread through blood transfusions, organ transplants, or from mother to baby during pregnancy, delivery, or ... Centers for Disease Control and Prevention (CDC) (2002). "Investigation of blood transfusion recipients with West Nile virus ...
... unless intrauterine blood transfusion is performed.[citation needed] Since hemoglobin Barts is elevated in alpha thalassaemia, ... It is moderately insoluble, and therefore accumulates in the red blood cells. It has an extremely high affinity for oxygen, ... "Predictive value of cord blood hematological indices and hemoglobin Barts for the detection of heterozygous alpha-thalassemia-2 ...
Positive direct Coombs test (might be negative after fetal interuterine blood transfusion) ... The woman may have received a therapeutic blood transfusion. ABO blood group system and the D antigen of the Rhesus (Rh) blood ... IUT - Intrauterine Transfusion (IUT) is done either by intraperitoneal transfusion (IPT) or intravenous transfusion (IVT).[19] ... transfusion with compatible packed red blood, exchange transfusion with a blood type compatible with both the infant and the ...
... by blood transfusions). There is some evidence that intrauterine Parvovirus B19 infection leads to developmental abnormalities ... This is termed "aplastic crisis" (also called reticulocytopenia). It is treated with blood transfusion. Parvovirus infection in ... It is classified as erythrovirus because of its capability to invade red blood cell precursors in the bone marrow. Three ... Although most patients have a decrease of erythropoiesis (production of red blood cells) during parvovirus infection, it is ...
Monozygotic twins who share a placenta can develop twin-to-twin transfusion syndrome. This condition means that blood from one ... There are two types of stillbirth, including intrauterine death and intrapartum death. Intrauterine death occurs when a baby ... Twin-to-twin transfusion syndromeEdit. Main article: Twin-to-twin transfusion syndrome ... The DNA in white blood cells of 66 pairs of monozygotic twins was analyzed for 506,786 single-nucleotide polymorphisms known to ...
... blood transfusion, intrauterine MeSH E02.095.135.469 --- exchange transfusion, whole blood MeSH E02.095.135.750 --- plasma ... lymphocyte transfusion MeSH E02.095.135.140.650 --- platelet transfusion MeSH E02.095.135.164 --- blood transfusion, autologous ... blood component transfusion MeSH E02.095.135.140.275 --- erythrocyte transfusion MeSH E02.095.135.140.425 --- leukocyte ...
... post of Director from 1946 to 1978 Dr Tovey was one of the first surgeons regularly to perform intrauterine blood transfusions ... He was also president of the International Society of Blood Transfusion. He was Consultant Adviser on Blood Transfusion at the ... In that year he was appointed Director of the South West Regional Blood Transfusion Service. It was in the evening of J D R ... During the Second World War, he joined the Royal Army Medical Corps and was posted to the Army Blood Transfusion Service from ...
1988). "Consequences of fetomaternal haemorrhage after intrauterine transfusion". BMJ. 297 (6660): 1379-81. doi:10.1136/bmj. ... Finally, a white blood cell count can detect maternal blood in the sample, as fetal white blood cells are primarily leukocytes ... If the blood sample was obtained at the site close to the placenta, a fetal blood confirmation test should be done to ensure no ... Suspicion of fetal infections, such as rubella and toxoplasmosis, as well as the need to supply medicine or blood transfusions ...
Monozygotic twins who share a placenta can develop twin-to-twin transfusion syndrome. This condition means that blood from one ... There are two types of stillbirth, including intrauterine death and intrapartum death. Intrauterine death occurs when a baby ... The DNA in white blood cells of 66 pairs of monozygotic twins was analyzed for 506,786 single nucleotide polymorphisms known to ... Polymorphisms appeared in 2 of the 33 million comparisons, leading the researchers to extrapolate that the blood cells of ...
Treatment includes surgery, blood transfusions, medications, and overnight stays (20). Unsafe abortions can lead to sepsis, ... Today, oral contraceptives, intra-uterine devices (IUDs), and male and female condoms are available for free at public health ...
A failure of cross-matching can allow donor blood of an incompatible blood group to be transfused, resulting in a transfusion ... Severe cases require intrauterine transfusions or early delivery to survive, while mild cases may only require phototherapy at ... Endothelium of the blood vessels is being damaged, therefore the graft is not sufficiently supplied with blood and is replaced ... by repeated blood transfusion). In case of hyperacute rejection, antibodies activate complement; moreover, the reaction can be ...
Patients report going every 2-3 weeks for blood transfusions. In addition, they must undertake chelation therapy to survive; ... commonly in neonates as intrauterine growth retardation). Congenital dyserythropoietic anemia type II-is defined by moderate ... the amount of blood received by the patient is not as important as their baseline pre-transfusion hemoglobin level. This is ... Treatment of individuals with CDA usually consist of frequent blood transfusions, but this can vary depending on the type that ...
IUT - Intrauterine Transfusion (IUT) is done either by intraperitoneal transfusion (IPT) or intravenous transfusion (IVT). IVT ... This would require a lot of extra work in blood transfusion departments and it is considered not economical to do the blood ... Newborn Screening Tests - Transfusion with donor blood during pregnancy or shortly after birth can affect the results of the ... Blood is taken from the mother, and using PCR, can detect the K, C, c, D, and E alleles of fetal DNA. This blood test is non- ...
For example, a blood group B individual who has received a transfusion of group O donor red cells may show mixed field ... This may result from intrauterine exchange of erythrocyte precursors between twins (twin chimerism) or two fertilized eggs fuse ... The cause of mixed field agglutinations should be sought prior to setting up blood for transfusion. By far the most common ... Twin chimerism results from mixing of blood between two twin fetuses through placental blood vessel anastomoses, leading to ...
Intrauterine blood transfusion Intraperitoneal transfusion-blood transfused into fetal abdomen Intravascular transfusion-blood ... Intrauterine fetal blood transfusion for Rh disease Summary of transfusion reactions in the US. ... Both parents were blood group O and the husband's blood was used to give the mother a blood transfusion, but the mother ... Maternal blood The Kleihauer-Betke test or flow cytometry on a postnatal maternal blood sample can confirm that fetal blood has ...
In cases of identical twins, they may even have Twin to Twin Transfusion Syndrome (TTTS). This means that the twins share the ... same placenta and blood and nutrients can then move between twins. The twins may also be suffering from Intrauterine Growth ... Resnik, R. (2002). "Intrauterine Growth Restriction" (PDF). Obstetrics and Gynecology. 99 (3): 490-496. doi:10.1097/00006250- ... Sebire, N.; Souka, A.; Skentou, H.; Geerts, L. & Nicolaides, K. (2000). "Early prediction of severe twin-to-twin transfusion ...
IUT - Intrauterine Transfusion (IUT) is done either by intraperitoneal transfusion (IPT) or intravenous transfusion (IVT). IVT ... Newborn Screening Tests - Transfusion with donor blood during pregnancy or shortly after birth can affect the results of the ... Blood is taken from the mother, and using PCR, can detect the K, C, c, D, and E alleles of fetal DNA. This blood test is non- ... Deka, Dipika (2016). "Intrauterine Transfusion". Journal of Fetal Medicine. 27 (3): 505. doi:10.1007/s40556-016-0072-4. PMID ...
Patients with Selective IgA deficiency are at risk of anaphylaxis from blood transfusions. These patients should receive IgA ... but has been associated with some congenital intrauterine infections. Pathogenesis of IgA Deficiency 'In IgA-deficient patients ... They may present with severe reactions including anaphylaxis to blood transfusions or intravenous immunoglobulin due to the ... Types include: When suspected, the diagnosis can be confirmed by laboratory measurement of IgA level in the blood. SigAD is an ...
Thus blood transfusion is frequent in the management of patients with this kind of pregnancy, with others even using tranexamic ... an acute abdomen with an intrauterine pregnancy and a fibroid uterus with an intrauterine pregnancy . Ideally the management of ... there is continuous hospitalization in a well-equipped and well-staffed maternity unit which has immediate blood transfusion ... It is a dangerous condition as there can be bleeding into the abdomen that results in low blood pressure and can be fatal. ...
Treatment may require blood transfusion or emergency hysterectomy. Placental abruption occurs in about 1 in 200 pregnancies. ... intrauterine growth restriction, and oligohydramnios (low levels of amniotic fluid). Pre-eclampsia Chronic hypertension. Short ... The accumulating blood pushes between the layers of the decidua, pushing the uterine wall and placenta apart. When the placenta ... Diagnosis is made retrospectively by finding an organized blood clot or a depressed area on a delivered placenta. Class 1: Mild ...
Interventional ultrasonography involves biopsy, emptying fluids, intrauterine Blood transfusion (Hemolytic disease of the ... Hemodynamics (blood circulation)Edit. Blood velocity can be measured in various blood vessels, such as middle cerebral artery ... A blood flow study is done prior to the injection, by power doppler. The blood flow can be destroyed and the node become ... Power doppler visualized blood flow can be eradicated, and there may be a drop in the cancer blood marker test, thyroglobulin, ...
Due to the possibility of adverse reactions such as excessive bleeding, which may require a blood transfusion, and incomplete ... Mifepristone is contraindicated in the presence of an intrauterine device, as well as with ectopic pregnancy, adrenal failure, ... Other incidents reported to the FDA included 612 nonlethal hospitalizations, 339 blood transfusions, 48 severe infections, and ... Mifepristone is used for the medical treatment of high blood sugar (hyperglycemia) caused by high cortisol levels in the blood ...
The exact cause is unclear.[1] Risk factors include congenital heart disease, birth asphyxia, exchange transfusion, and ... The gut mucosal cells do not get enough nourishment from arterial blood supply to stay healthy, especially in very premature ... Intrauterine hypoxia. *Infant respiratory distress syndrome. *Transient tachypnea of the newborn. *Meconium aspiration syndrome ... Preterm birth, congenital heart disease, birth asphyxia, exchange transfusion, prolonged rupture of membranes[1]. ...
... Treatment Overview. An intrauterine transfusion provides blood to an Rh- ... An intrauterine fetal blood transfusion is done in the hospital. The mother may have to stay overnight after the procedure. ... A blood transfusion is given to replace fetal red blood cells that are being destroyed by the Rh-sensitized mothers immune ... the method of transfusion, and the skill of the doctor who does the procedure. Overall, after intrauterine transfusion through ...
... Treatment Overview. An intrauterine transfusion provides blood to an Rh- ... An intrauterine fetal blood transfusion is done in the hospital. The mother may have to stay overnight after the procedure. ... A blood transfusion is given to replace fetal red blood cells that are being destroyed by the Rh-sensitized mothers immune ... Home , Healthy Living , Health Library , Intrauterine Fetal Blood Transfusion for Rh Disease ...
... usually caused by Rh incompatibility between the mothers blood type and that of ... attack the red blood cells of the fetus. An intrauterine transfusion of blood may be indicated. ... usually caused by Rh incompatibility between the mothers blood type and that of the fetus, ...
Sepsis; Blood transfusions; Days of hospitalization; Long term outcomes including neurodevelopmental outcome ... Birthweight; Perinatal mortality; Congenital anomalies; Intrauterine growth retardation; Respiratory distress syndrome; Chronic ... 1.Maternal mortality 2.Route of delivery 3.Infection related complications 4.Bleeding, blood loss and transfusion requirements ... Correlation between changes in MR signals and dietary Mn intake, number of days on PN and blood Mn levels ...
Sepsis; Blood transfusions; Days of hospitalization; Long term outcomes including neurodevelopmental outcome [ Time Frame: ... Intrauterine growth retardation: definition, classification, and etiology. Clin Obstet Gynecol. 1992 Mar;35(1):99-107. Review. ... 1.Maternal mortality 2.Route of delivery 3.Infection related complications 4.Bleeding, blood loss and transfusion requirements ... The bank of biological fluids and tissues will include maternal blood, umbilical cord plasma, amniotic fluid, maternal urine ...
Fetal Blood Sampling and Intrauterine Transfusion. Lack of blood cells, or fetal anemia, causes the unborn babys heart to pump ... your doctor may perform fetal intrauterine transfusion to replace destroyed blood cells. Our maternal-fetal medicine ... If a blood test reveals a potential problem, your doctor may recommend more comprehensive testing, such as amniocentesis or CVS ... To check for signs of fetal anemia, your doctor extracts a small amount of blood from your unborn babys umbilical cord. This ...
Intrauterine growth restriction at , 3% for weight at birth since this has been shown to alter mesenteric BFV and the post- ... The Effect of Blood Transfusion on Blood Flow to the Intestines of Premature Infants. The safety and scientific validity of ... The purpose of the study is to see if a blood transfusion changes how fast blood flows to the intestines of a premature baby. ... The effects of a blood transfusion on superior mesenteric artery blood flow velocity and the post-prandial hyperemia are not ...
Placement of an intrauterine device (IUD); Placement of an intrauterine hormone-releasing system (IUS); Bilateral tubal ... Luspatercept improves hemoglobin levels and blood transfusion requirements in a study of patients with β-thalassemia. Blood. ... MedlinePlus related topics: Blood Transfusion and Donation Thalassemia Genetic and Rare Diseases Information Center resources: ... Proportion of subjects with a ≥50% reduction in red blood cell (RBC) transfusion burden from week 37 to Week 48 [ Time Frame: ...
Placement of an intrauterine device (IUD); Placement of an intrauterine hormone-releasing system (IUS); Bilateral tubal ... MedlinePlus related topics: Blood Transfusion and Donation Thalassemia Genetic and Rare Diseases Information Center resources: ... Proportion of subjects with a ≥50% reduction in red blood cell (RBC) transfusion burden from week 37 to Week 48 [ Time Frame: ... Proportion of subjects with a ≥50% reduction in red blood cell (RBC) transfusion burden from week 13 to Week 24 [ Time Frame: ...
Main outcome measures Anthropometry, blood pressure, lipids, heart rate variability and cardiac MRI, including myocardial ... Objective To compare long-term cardiovascular outcomes in survivors of fetal anaemia and intrauterine transfusion with those of ... These findings are relevant to the long-term health of intrauterine transfusion recipients, and may potentially also have ... Participants Adults who received intrauterine transfusion for anaemia due to rhesus disease (exposed) and their unexposed ...
Other routes include sexual transmission, blood transfusions and laboratory exposure. There is a theoretical concern of ... Maternal-fetal infections have occurred intrauterine and perinatally. ... So the first most important thing is Zika virus usually remains in the blood of an infected person just for a few days and up ... To address the transfusion question, we do know that other flaviviruses that are arthropod-borne have been implicated in ...
Intrauterine growth restriction: screening, diagnosis, and management. J Obstet Gynaecol Can 2013;35(8):741-757. ... Indications for blood transfusion in pregnancy with sickle cell disease. Aust N Z J Obstet Gynaecol 1995;35(4):405-408. ... Prophylactic red blood cell exchange may be beneficial in the management of sickle cell disease in pregnancy. Transfusion 2015; ... acute and delayed transfusion reactions, transfusion-related infectious morbidity, and iron overload,13 transfusion in the ...
... blood transfusion; and laboratory exposure (1-5). Most Zika virus infections are asymptomatic (1,6). Clinical illness, when it ... Zika virus infections have also been documented through intrauterine transmission resulting in congenital infection; ... Revised recommendations for reducing the risk of Zika virus transmission by blood and blood components: guidance for industry. ... as well as testing of all blood donations collected in the United States and its territories to reduce the risk for transfusion ...
Transmission of West Nile virus through blood transfusion in the United States in 2002. N Engl J Med 2003;349:1236--45. ... Intrauterine West Nile virus: ocular and systemic findings. Am J Ophthalmol 2003;136:733--5. ... red blood cells, or fresh frozen plasma from 16 viremic blood donors (31). National blood donation screening began in 2003 but ... Non-mosquito WNV transmission through blood transfusions, transplanted organs, transplacentally from mother to fetus, and via ...
... received 31 intravascular transfusions (13 exchange and 18 bolus) and one intraperitoneal transfusion under ultrasonographic ... Blood Transfusion, Intrauterine / adverse effects, methods*. Exchange Transfusion, Whole Blood / adverse effects, methods*. ... Procedure time for the bolus transfusion was shorter than for the exchange transfusion (t test, p less than 0.001). Bleeding ... and one intraperitoneal transfusion under ultrasonographic guidance. The interval between transfusions was 13.4 +/- 4.7 days. ...
Intrauterine fetal blood transfusions. *Fetal tissue biopsy. *Diagnostic fetoscopy. More information on laser surgery for twin- ... Laser surgery for Twin-twin Transfusion Syndrome (TTTS). *Laser surgery for selective intrauterine growth ristriction in ... A small amount of blood is taken for the test and the results are known with 4-5 days. ...
It may also happen if the mom and baby have different blood types. ... It happens when the Rh factors in the moms and babys blood dont match. ... Intrauterine blood transfusion. This test puts red blood cells into your babys circulation. In this test, a needle is placed ... Percutaneous umbilical cord blood sampling or fetal blood sampling. In this test, a blood sample is taken from your babys ...
Intrauterine blood transfusion. This test puts red blood cells into your babys circulation. In this test, a needle is placed ... Percutaneous umbilical cord blood sampling or fetal blood sampling. In this test, a blood sample is taken from your babys ... Almost all women will have a blood test to learn their blood type early in pregnancy. ... The Rh factor is a protein on the covering of the red blood cells. If the Rh factor protein is on the cells, the person is Rh ...
INTRA-UTERINE FOETAL BLOOD TRANSFUSION. S Afr Med J. 1965 Jul 31; 39:630-4. PMID: 14338516. ... Hot Flash Frequency and Blood Pressure: Data from the Study of Womens Health Across the Nation. J Womens Health (Larchmt). ...
twin-to-twin transfusion syndrome, which occurs when one baby gets more blood than the other baby ... intrauterine growth restriction, or delayed fetal growth. Once youre diagnosed with a twin pregnancy, your course of treatment ... Your weight, heart rate, and blood pressure will be checked.. *Your doctor will order routine blood tests and ask for a urine ... Increased blood flow to your kidneys also contributes to more frequent urination. ...
Intrauterine Blood Transfusion 08/01/2000 - "We describe a girl with DiGeorge anomaly and normal cytogenetic and molecular ... whose clinical course was complicated by graft versus host disease caused by intrauterine materno-fetal transfusion, and ... XX male with velocardiofacial syndrome and a deletion of 22q11.2 and no evidence of Y chromosomal loci in blood DNA was ...
Transmission can be oral, sexual, via blood transfusion, organ transplantation, intrauterine, or perinatal. Infection with CMV ... The human Cytomegalovirus (CMV) is found in blood, tissues and nearly all secretory fluids of infected persons. ... EDTA plasma specimens that have been stored inappropriately which include the following storage conditions: whole blood that ... has been frozen; whole blood processed for plasma more than 24 hours after collection; plasma stored at room temperature for ...
Intrauterine transfusions for red blood cell maternofetal incompatibility in monochorionic diamniotic twin pregnancy. ... Intrauterine blood transfusion: Status report of 4years of practice in France (2011-2014)]. ... Postponing early intrauterine transfusion with intravenous immunoglobulin treatment: the PETIT study on severe hemolytic ... Fetal Brain Injury Associated with Parvovirus B19 Congenital Infection Requiring Intrauterine Transfusion. ...
... is a blood disorder in a fetus or newborn infant. In some infants, it can be fatal. ... Severe HDN may be treated before birth by intrauterine blood transfusions.. Prevention. ... Medicines to raise blood pressure if it drops too low.. *In severe cases, an exchange transfusion may need to be performed. ... Fresh donor blood is infused.. *Simple transfusion (without exchange). This may need to be repeated after the baby goes home ...
The aim of our study was to evaluate the middle cerebral artery velocimetry before and after intrauterine blood transfusion in ... Intrauterine blood transfusion in immune hydrops fetalis, corrects middle cerebral artery Doppler ... ... Techniques of intrauterine fetal transfusion for women with red-cell isoimmunisation for improving ... ... Although islet blood flow has been studied extensively, little is known about the dynamics of islet blood flow during ...
  • Blood flow is measured by an ultrasound test. (clinicaltrials.gov)
  • If your healthcare provider notices signs that your baby is not progressing as expected, they will run additional tests to determine an underlying cause, including an ultrasound and blood tests. (healthline.com)
  • It allows the application of ultrasound technology, such as piezoelectric transducer or CMUT, to see from inside blood vessels out through the surrounding blood column, visualizing the endothelium (inner wall) of blood vessels in living individuals. (wikipedia.org)
  • The development of amniocentesis in 1952, fetal blood sampling during labor in the early 1960s, more precise fetal heart monitoring in 1968, and real-time ultrasound in 1971 resulted in early intervention and lower mortality rates. (wikipedia.org)
  • Normally, red blood cells (RBCs) last for about 120 days in the body. (medlineplus.gov)
  • In this disorder, RBCs in the blood are destroyed quickly and thus do not last as long. (medlineplus.gov)
  • Expression is limited to red blood cells (RBCs), with an increasing density during their maturation, unlike the ABH system, which exists in a wide variety of tissues. (medscape.com)
  • Participants Adults who received intrauterine transfusion for anaemia due to rhesus disease (exposed) and their unexposed sibling(s). (bmj.com)
  • Conclusions This study provides the first evidence in humans that cardiovascular development is altered following exposure to fetal anaemia and intrauterine transfusion, with persistence of these changes into adulthood potentially indicating increased risk of cardiovascular disease. (bmj.com)
  • At the extreme of this, very small transducers can be mounted on small diameter catheters and placed into blood vessels to image the walls and disease of those vessels. (wikipedia.org)
  • Hereditary haemochromatosis (HHC) is a frequent disease in Brittany (5 to 7‰), responsible first for biological disorder in blood iron parameters and minor clinical disorders, before evolving to potential life-threatening consequences such as diabetes, liver cirrhosis and congestive heart failure. (clinicaltrials.gov)
  • The loss of this small amount of blood may however be a sensitising event and stimulate antibody production to the foetal red blood cells, an example of which is Rhesus disease of the newborn. (wikipedia.org)
  • While the only diagnostic "gold standard" mechanism of diagnosis en vivo is via kidney biopsy, the clinical conditions and blood clotting disorder often associated with this disease may make it impractical in a clinical setting. (wikipedia.org)
  • citation needed] Testing for HDN involves blood work from both mother and father, and may also include assessment with amniocentesis and Middle Cerebral Artery scans. (wikipedia.org)
  • Menorrhagia may be caused by a disruption in the regulation of the menstrual cycle by hormones, disorders that affect the endometrial womb lining and abnormalities affecting the blood clotting process. (medic8.com)
  • The paucity of reported TT-WNV infections and the screening results suggest that blood safety interventions are effective. (cdc.gov)
  • Infections can develop in the neonate transplacentally, perinatally (from vaginal secretions or blood), or postnatally (from breast milk or other sources). (medscape.com)
  • 6 This thought changed when 23 cases of WNV infections were reported after blood transfusions in 2002. (uspharmacist.com)
  • The main reasons for higher than normal Epo are chronic hypoxia (poor blood oxygen levels over the long-term), poor oxygen delivery due to abnormal red blood cell structure, and tumors releasing inappropriately high amounts of Epo. (emedicinehealth.com)
  • In secondary polycythemia, factors external to red blood cell production (for example, hypoxia, sleep apnea , certain tumors) result in polycythemia. (medicinenet.com)
  • Both disorders occur only in monochorionic twins and result from unbalanced blood flow through placental vascular anastomoses. (jove.com)