Blood Transfusion, Autologous
The transfer of erythrocytes from a donor to a recipient or reinfusion to the donor.
The transfer of blood platelets from a donor to a recipient or reinfusion to the donor.
Exchange Transfusion, Whole Blood
Repetitive withdrawal of small amounts of blood and replacement with donor blood until a large proportion of the blood volume has been exchanged. Used in treatment of fetal erythroblastosis, hepatic coma, sickle cell anemia, disseminated intravascular coagulation, septicemia, burns, thrombotic thrombopenic purpura, and fulminant malaria.
Blood Component Transfusion
The transfer of blood components such as erythrocytes, leukocytes, platelets, and plasma from a donor to a recipient or back to the donor. This process differs from the procedures undertaken in PLASMAPHERESIS and types of CYTAPHERESIS; (PLATELETPHERESIS and LEUKAPHERESIS) where, following the removal of plasma or the specific cell components, the remainder is transfused back to the donor.
Blood Transfusion, Intrauterine
In utero transfusion of BLOOD into the FETUS for the treatment of FETAL DISEASES, such as fetal erythroblastosis (ERYTHROBLASTOSIS, FETAL).
Blood Grouping and Crossmatching
Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion.
Operative Blood Salvage
A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
Antifibrinolytic hemostatic used in severe hemorrhage.
The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.
Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.
Members of a religious denomination founded in the United States during the late 19th century in which active evangelism is practiced, the imminent approach of the millennium is preached, and war and organized government authority in matters of conscience are strongly opposed (from American Heritage Dictionary of the English Language, 4th ed). Jehovah's Witnesses generally refuse blood transfusions and other blood-based treatments based on religious belief.
Blood Group Incompatibility
An antigenic mismatch between donor and recipient blood. Antibodies present in the recipient's serum may be directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984).
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
The mildest form of erythroblastosis fetalis in which anemia is the chief manifestation.
Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.
Substances that are used in place of blood, for example, as an alternative to BLOOD TRANSFUSIONS after blood loss to restore BLOOD VOLUME and oxygen-carrying capacity to the blood circulation, or to perfuse isolated organs.
The preparation of platelet concentrates with the return of red cells and platelet-poor plasma to the donor.
A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.
A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.
Antibodies from an individual that react with ISOANTIGENS of another individual of the same species.
Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure.
Leukocyte Reduction Procedures
The removal of LEUKOCYTES from BLOOD to reduce BLOOD TRANSFUSION reactions and lower the chance of transmitting VIRUSES. This may be performed by FILTRATION or by CYTAPHERESIS.
Anemia, Sickle Cell
A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)
International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.
Surgical Procedures, Elective
Surgery which could be postponed or not done at all without danger to the patient. Elective surgery includes procedures to correct non-life-threatening medical problems as well as to alleviate conditions causing psychological stress or other potential risk to patients, e.g., cosmetic or contraceptive surgery.
Infectious organisms in the BLOOD, of which the predominant medical interest is their contamination of blood-soiled linens, towels, gowns, BANDAGES, other items from individuals in risk categories, NEEDLES and other sharp objects, MEDICAL WASTE and DENTAL WASTE, all of which health workers are exposed to. This concept is differentiated from the clinical conditions of BACTEREMIA; VIREMIA; and FUNGEMIA where the organism is present in the blood of a patient as the result of a natural infectious process.
INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally, and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.
Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.
A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)
Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).
A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.
A subnormal level of BLOOD PLATELETS.
Hepatitis C Antibodies
Antibodies to the HEPATITIS C ANTIGENS including antibodies to envelope, core, and non-structural proteins.
Blood Coagulation Disorders
Surgical Procedures, Operative
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.
Hepatitis, Viral, Human
A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
Peptic Ulcer Hemorrhage
The indelible marking of TISSUES, primarily SKIN, by pricking it with NEEDLES to imbed various COLORING AGENTS. Tattooing of the CORNEA is done to colorize LEUKOMA spots.
Rh-Hr Blood-Group System
Erythrocyte isoantigens of the Rh (Rhesus) blood group system, the most complex of all human blood groups. The major antigen Rh or D is the most common cause of erythroblastosis fetalis.
Iron Chelating Agents
Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems.
The religion stemming from the life, teachings, and death of Jesus Christ: the religion that believes in God as the Father Almighty who works redemptively through the Holy Spirit for men's salvation and that affirms Jesus Christ as Lord and Savior who proclaimed to man the gospel of salvation. (From Webster, 3d ed)
INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.
Blood Group Antigens
The aggregate of various economic, political, and social policies by which an imperial power maintains or extends its control over other areas or peoples. It includes the practice of or belief in acquiring and retaining colonies. The emphasis is less on its identity as an ideological political system than on its designation in a period of history. (Webster, 3d ed; from Dr. J. Cassedy, NLM History of Medicine Division)
Wounds and Injuries
Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.
Anemia, Hemolytic, Autoimmune
Acquired hemolytic anemia due to the presence of AUTOANTIBODIES which agglutinate or lyse the patient's own RED BLOOD CELLS.
A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.
Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.
Acute Lung Injury
A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
ABO Blood-Group System
The major human blood type system which depends on the presence or absence of two antigens A and B. Type O occurs when neither A nor B is present and AB when both are present. A and B are genetic factors that determine the presence of enzymes for the synthesis of certain glycoproteins mainly in the red cell membrane.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
The insertion of a catheter through the skin and body wall into the kidney pelvis, mainly to provide urine drainage where the ureter is not functional. It is used also to remove or dissolve renal calculi and to diagnose ureteral obstruction.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle cell conditions.
Blood Cell Count
Patient Identification Systems
Fibrin Tissue Adhesive
An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.
A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.
Acute hemorrhage or excessive fluid loss resulting in HYPOVOLEMIA.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.
A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.
Blood Specimen Collection
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Acquired degenerative dilation or expansion (ectasia) of normal BLOOD VESSELS, often associated with aging. They are isolated, tortuous, thin-walled vessels and sources of bleeding. They occur most often in mucosal capillaries of the GASTROINTESTINAL TRACT leading to GASTROINTESTINAL HEMORRHAGE and ANEMIA.
A species of protozoa infecting humans via the intermediate tick vector IXODES scapularis. The other hosts are the mouse PEROMYSCUS leucopus and meadow vole MICROTUS pennsylvanicus, which are fed on by the tick. Other primates can be experimentally infected with Babesia microti.
Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.
Organic and inorganic compounds that contain iron as an integral part of the molecule.
A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Otorhinolaryngologic Surgical Procedures
Disease Transmission, Infectious
A family of RNA viruses, many of which cause disease in humans and domestic animals. There are three genera FLAVIVIRUS; PESTIVIRUS; and HEPACIVIRUS, as well as several unassigned species.
Kell Blood-Group System
A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)
Injury Severity Score
Hepatitis B Surface Antigens
Those hepatitis B antigens found on the surface of the Dane particle and on the 20 nm spherical and tubular particles. Several subspecificities of the surface antigen are known. These were formerly called the Australia antigen.
Coronary Artery Bypass
A prolonged painful erection that may lasts hours and is not associated with sexual activity. It is seen in patients with SICKLE CELL ANEMIA, advanced malignancy, spinal trauma; and certain drug treatments.
Multiple Organ Failure
Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their major function is to store IRON in a nontoxic bioavailable form. Each ferritin molecule consists of ferric iron in a hollow protein shell (APOFERRITINS) made of 24 subunits of various sequences depending on the species and tissue types.
Severity of Illness Index
Identification of the major histocompatibility antigens of transplant DONORS and potential recipients, usually by serological tests. Donor and recipient pairs should be of identical ABO blood group, and in addition should be matched as closely as possible for HISTOCOMPATIBILITY ANTIGENS in order to minimize the likelihood of allograft rejection. (King, Dictionary of Genetics, 4th ed)
Hydroxyethyl Starch Derivatives
Accumulations of blood in the PERITONEAL CAVITY due to internal HEMORRHAGE.
Reduction in baroreflex cardiovascular responses due to venous infusion in the rabbit. (1/3107)We studied reflex bradycardia and depression of mean arterial blood pressure (MAP) during left aortic nerve (LAN) stimulation before and after volume infusion in the anesthetized rabbit. Step increases in mean right atrial pressure (MRAP) to 10 mm Hg did not result in a significant change in heart rate or MAP. After volume loading, responses to LAN stimulation were not as great and the degree of attenuation was propoetional to the level of increased MRAP. A change in responsiveness was observed after elevation of MRAP by only 1 mm Hg, corresponding to less than a 10% increase in average calculated blood volume. after an increase in MRAP of 10 mm Hg, peak responses were attenuated by 44% (heart rate) and 52% (MAP), and the initial slopes (rate of change) were reduced by 46% (heart rate) and 66% (MAP). Comparison of the responses after infusion with blood and dextran solutions indicated that hemodilution was an unlikely explanation for the attenuation of the reflex responses. Total arterial baroreceptor denervation (ABD) abolished the volume-related attenuation was still present following bilateral aortic nerve section or vagotomy. It thus appears that the carotid sinus responds to changes inblood volume and influences the reflex cardiovascular responses to afferent stimulation of the LAN. On the other hand, cardiopulmonary receptors subserved by vagal afferents do not appear to be involved. (+info)
A prospective study on TT virus infection in transfusion-dependent patients with beta-thalassemia. (2/3107)A novel DNA virus designated TT virus (TTV) has been reported to be involved in the development of posttransfusion non-A-C hepatitis. We evaluated the frequency and natural course of TTV infection in a cohort of transfusion-dependent thalassemic patients in a 3-year follow-up study. Ninety-three serum hepatitis C virus (HCV) antibody-negative patients (median age of 8 years; range, 0 to 25) from eight centers were studied. Of them, 34 (37%) had an abnormal alanine-aminotransferase (ALT) baseline pattern, and the other 12 (13%) showed ALT flare-ups during the follow-up. TTV DNA in patient sera collected at the time of enrollment and at the end of follow-up was determined by polymerase chain reaction (PCR). In parallel, serum samples from 100 healthy blood donors were also tested. At baseline, 87 patient sera (93.5%) tested positive for the TTV DNA. Of these TTV DNA-positive patients, 84 (96.5%) remained viremic at the end of the study period. Of the 6 TTV DNA-negative patients, 3 acquired TTV infection during follow-up. However, no definite relation was observed between the results of TTV DNA determination and ALT patterns. TTV viremia was also detectable in 22% of blood donors. In conclusion, TTV infection is frequent and persistent among Italian transfusion-dependent patients. The high rate of viremia observed in healthy donors indicates that the parenteral route is not the only mode of TTV spread. (+info)
Soluble HLA class I, HLA class II, and Fas ligand in blood components: a possible key to explain the immunomodulatory effects of allogeneic blood transfusions. (3/3107)The immunomodulatory effect of allogeneic blood transfusions (ABT) has been known for many years. However, a complete understanding of the effects of ABT on the recipient's immune system has remained elusive. Soluble HLA class I (sHLA-I), HLA class II (sHLA-II), and Fas ligand (sFasL) molecules may play immunoregulatory roles. We determined by double-determinant immunoenzymatic assay (DDIA) sHLA-I, sHLA-II, and sFasL concentrations in different blood components. sHLA-I and sFasL levels in red blood cells (RBCs) stored for up to 30 days and in random-donor platelets are significantly (P <.001) higher than in other blood components and their amount is proportionate to the number of residual donor leukocytes and to the length of storage. Blood components with high sHLA-I and sFasL levels play immunoregulatory roles in vitro as in allogeneic mixed lymphocyte responses (MLR) and antigen-specific cytotoxic T-cell (CTL) activity, and induce apoptosis in Fas-positive cells. These data suggest that soluble molecules in blood components are functional. If these results are paralleled in vivo, they should be taken into account in transfusion practice. Blood components that can cause immunosuppression should be chosen to induce transplantation tolerance, whereas blood components that lack immunosuppressive effects should be preferred to reduce the risk of postoperative complications and cancer recurrence. (+info)
Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly(ethylene glycol). (4/3107)We previously showed that the covalent modification of the red blood cell (RBC) surface with methoxypoly(ethylene glycol) [mPEG; MW approximately 5 kD] could significantly attenuate the immunologic recognition of surface antigens. However, to make these antigenically silent RBC a clinically viable option, the mPEG-modified RBC must maintain normal cellular structure and functions. To this end, mPEG-derivatization was found to have no significant detrimental effects on RBC structure or function at concentrations that effectively blocked antigenic recognition of a variety of RBC antigens. Importantly, RBC lysis, morphology, and hemoglobin oxidation state were unaffected by mPEG-modification. Furthermore, as shown by functional studies of Band 3, a major site of modification, PEG-binding does not affect protein function, as evidenced by normal SO4- flux. Similarly, Na+ and K+ homeostasis were unaffected. The functional aspects of the mPEG-modified RBC were also maintained, as evidenced by normal oxygen binding and cellular deformability. Perhaps most importantly, mPEG-derivatized mouse RBC showed normal in vivo survival ( approximately 50 days) with no sensitization after repeated transfusions. These data further support the hypothesis that the covalent attachment of nonimmunogenic materials (eg, mPEG) to intact RBC may have significant application in transfusion medicine, especially for the chronically transfused and/or allosensitized patient. (+info)
Endoscopic retreatment compared with surgery in patients with recurrent bleeding after initial endoscopic control of bleeding ulcers. (5/3107)BACKGROUND AND METHODS: After endoscopic treatment to control bleeding of peptic ulcers, bleeding recurs in 15 to 20 percent of patients. In a prospective, randomized study, we compared endoscopic retreatment with surgery after initial endoscopy. Over a 40-month period, 1169 of 3473 adults who were admitted to our hospital with bleeding peptic ulcers underwent endoscopy to reestablish hemostasis. Of 100 patients with recurrent bleeding, 7 patients with cancer and 1 patient with cardiac arrest were excluded from the study; 48 patients were randomly assigned to undergo immediate endoscopic retreatment and 44 were assigned to undergo surgery. The type of operation used was left to the surgeon. Bleeding was considered to have recurred in the event of any one of the following: vomiting of fresh blood, hypotension and melena, or a requirement for more than four units of blood in the 72-hour period after endoscopic treatment. RESULTS: Of the 48 patients who were assigned to endoscopic retreatment, 35 had long-term control of bleeding. Thirteen underwent salvage surgery, 11 because retreatment failed and 2 because of perforations resulting from thermocoagulation. Five patients in the endoscopy group died within 30 days, as compared with eight patients in the surgery group (P=0.37). Seven patients in the endoscopy group (including 6 who underwent salvage surgery) had complications, as compared with 16 in the surgery group (P=0.03). The duration of hospitalization, the need for hospitalization in the intensive care unit and the resultant duration of that stay, and the number of blood transfusions were similar in the two groups. In multivariate analysis, hypotension at randomization (P=0.01) and an ulcer size of at least 2 cm (P=0.03) were independent factors predictive of the failure of endoscopic retreatment. CONCLUSIONS: In patients with peptic ulcers and recurrent bleeding after initial endoscopic control of bleeding, endoscopic retreatment reduces the need for surgery without increasing the risk of death and is associated with fewer complications than is surgery. (+info)
Primary percutaneous transluminal coronary angioplasty performed for acute myocardial infarction in a patient with idiopathic thrombocytopenic purpura. (6/3107)A 72-year-old female with idiopathic thrombocytopenic purpura (ITP) complained of severe chest pain. Electrocardiography showed ST-segment depression and negative T wave in I, aVL and V4-6. Following a diagnosis of acute myocardial infarction (AMI), urgent coronary angiography revealed 99% organic stenosis with delayed flow in the proximal segment and 50% in the middle segment of the left anterior descending artery (LAD). Subsequently, percutaneous transluminal coronary angioplasty (PTCA) for the stenosis in the proximal LAD was performed. In the coronary care unit, her blood pressure dropped. Hematomas around the puncture sites were observed and the platelet count was 28,000/mm3. After transfusion, electrocardiography revealed ST-segment elevation in I, aVL and V1-6. Urgent recatheterization disclosed total occlusion in the middle segment of the LAD. Subsequently, PTCA was performed successfully. Then, intravenous immunoglobulin increased the platelet count and the bleeding tendency disappeared. A case of AMI with ITP is rare. The present case suggests that primary PTCA can be a useful therapeutic strategy, but careful attention must be paid to hemostasis and to managing the platelet count. (+info)
Hormonal changes in thalassaemia major. (7/3107)Patients with severe thalassaemia major suffer endocrine and other abnormalities before their eventual death from iron overload due to repeated blood transfusions. The endocrine status of 31 thalassaemic patients aged 2-5 to 23 years was investigated. Exact data were available on the rate and duration of blood transfusion in all of them and in many the liver iron concentration was also known. Although the patients were euthyroid, the mean serum thyroxine level was significantly lower, and the mean thyrotrophic hormone level significantly higher, compared with the values found in normal children. Forty oral glucose tolerance tests with simultaneous insulin levels were performed in 19 children, of whom 5 developed symptomatic diabetes and one had impaired tolerance. Previous tests on all 6 patients were available and some showed raised insulin levels possibly due to insulin resistance. 2 patients had clinical hypoparathyroidism and are described. The parathyroid hormone levels determined by radioimmunoassay in 25 patients were below the mean for the age group in all and outside the reference range in 16. Nonfasting plasma calcium levels were not reduced. Puberty was delayed in some patients. Concentrations of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) measured in urine from 7 girls and 5 boys showed considerable variation. In the boys there was an overall tendency for FSH and LH excretion to be low with regard to age, but with respect to puberty rating FSH exretions were normal or low and LH normal or raised. The girls showed a tendency for LH but not FSH excretion to be raised in relation to puberty rating. The severity of the endocrine changes was related to the degree of iron loading and is discussed in relation to previous work in which the iron loading has rarely been accurately indicated nor parathyroid status assessed. (+info)
Prospective randomized multicenter study comparing cyclosporin alone versus the combination of antithymocyte globulin and cyclosporin for treatment of patients with nonsevere aplastic anemia: a report from the European Blood and Marrow Transplant (EBMT) Severe Aplastic Anaemia Working Party. (8/3107)We report the results of the first prospective randomized multicenter study of immunosuppressive treatment in patients with previously untreated nonsevere aplastic anemia (AA) as defined by a neutrophil count of at least 0.5 x 10(9)/L and transfusion dependence. Patients were randomized to receive cyclosporin (CSA) alone or the combination of horse antithymocyte globulin ([ATG] Lymphoglobuline; Merieux, Lyon, France) and CSA. The endpoint of the study was the hematologic response at 6 months. One hundred fifteen patients were randomized and assessable with a median follow-up period of 36 months; 61 received CSA and 54 ATG and CSA. In the CSA group, the percentage of complete and partial responders was 23% and 23%, respectively, for an overall response rate of 46%. A significantly higher overall response rate of 74% was found in the ATG and CSA group, with 57% complete and 17% partial responders (P =. 02). Compared with CSA alone, the combination of ATG and CSA resulted in a significantly higher median hemoglobin level and platelet count at 6 months. Fewer patients required a second course of treatment before 6 months due to a nonresponse. In the CSA group, 15 of 61 (25%) patients required a course of ATG before 6 months because of disease progression, compared with only 3 of 54 (6%) in the ATG and CSA group. The survival probabilities for the two groups were comparable, 93% (CSA group) and 91% (ATG and CSA group), but at 180 days, the prevalence of patients surviving free of transfusions, which excluded patients requiring second treatment because of nonresponse, death, disease progression, or relapse, was 67% in the CSA group and 90% in the ATG and CSA group (P =.001). We conclude that the combination of ATG and CSA is superior to CSA alone in terms of the hematologic response, the quality of response, and early mortality, and a second course of immunosuppression is less frequently required. (+info)
Early autologous fresh whole blood transfusion leads to less allogeneic transfusions and is safe<...
TY - JOUR. T1 - Early autologous fresh whole blood transfusion leads to less allogeneic transfusions and is safe. AU - Rhee, Peter. AU - Inaba, Kenji. AU - Pandit, Viraj. AU - Khalil, Mazhar. AU - Siboni, Stefano. AU - Vercruysse, Gary. AU - Kulvatunyou, Narong. AU - Tang, Andrew. AU - Asif, Anum. AU - OKeeffe, Terence. AU - Joseph, Bellal. PY - 2015/4/4. Y1 - 2015/4/4. N2 - BACKGROUND: The practice of transfusing ones own shed whole blood has obvious benefits such as reducing the need for allogeneic transfusions and decreasing the need for other fluids that are typically used for resuscitation in trauma. It is not widely adopted in the trauma setting because of the concern of worsening coagulopathy and the inflammatory process. The aim of this study was to assess outcomes in trauma patients receiving whole blood autotransfusion (AT) from hemothorax. METHODS: This is a multi-institutional retrospective study of all trauma patients who received autologous whole blood transfusion from hemothorax ...
Cancer incidence in blood transfusion recipients.<...
TY - JOUR. T1 - Cancer incidence in blood transfusion recipients.. AU - Hjalgrim, Henrik. AU - Edgren, Gustaf. AU - Rostgaard, Klaus. AU - Reilly, Marie. AU - Tran, Trung Nam. AU - Titlestad, Kjell. AU - Shanwell, Agneta. AU - Jersild, Casper. AU - Adami, Johanna. AU - Wikman, Agneta. AU - Gridley, Gloria. AU - Wideroff, Louise. AU - Nyrén, Olof. AU - Melbye, Mads. PY - 2007/12/19. Y1 - 2007/12/19. N2 - BACKGROUND: Blood transfusions may influence the recipients cancer risks both through transmission of biologic agents and by modulation of the immune system. However, cancer occurrence in transfusion recipients remains poorly characterized. METHODS: We used computerized files from Scandinavian blood banks to identify a cohort of 888,843 cancer-free recipients transfused after 1968. The recipients were followed from first registered transfusion until the date of death, emigration, cancer diagnosis, or December 31, 2002, whichever came first. Relative risks were expressed as ratios of the ...
sentinel HIV through blood transfusion
HIV THROUGH BLOOD TRANSFUSION. In the event that the insured contracted HIV as a result of blood transfusion, 10% on the Principal Sum Insured is payable. If you wish to apply for The Personal Sentinel coverage, just instruct us by e-mail providing the following details and we will be sending you the appropriate Application Form:-. ...
Desmopressin use for minimising perioperative blood transfusion. - Nuffield Department of Orthopaedics, Rheumatology and...
Blood transfusion is administered during many types of surgery, but its efficacy and safety are increasingly questioned. Evaluation of the efficacy of agents, such as desmopressin (DDAVP; 1-deamino-8-D-arginine-vasopressin), that may reduce perioperative blood loss is needed.To examine the evidence for the efficacy of DDAVP in reducing perioperative blood loss and the need for red cell transfusion in people who do not have inherited bleeding disorders.We searched for randomised controlled trials (RCTs) in the Cochrane Central Register of Controlled Trials (2017, issue 3) in the Cochrane Library, MEDLINE (from 1946), Embase (from 1974), the Cumulative Index to Nursing and Allied Health Literature (CINAHL) (from 1937), the Transfusion Evidence Library (from 1980), and ongoing trial databases (all searches to 3 April 2017).We included randomised controlled trials comparing DDAVP to placebo or an active comparator (e.g. tranexamic acid, aprotinin) before, during, or immediately after surgery or after
Orijen Fit & Trim - Wholesome Hound
Fresh chicken meat (14%), fresh cage-free eggs (6%), fresh whole herring (6%), fresh turkey meat (6%), fresh chicken liver (6%), fresh whole flounder (4%), fresh whole mackerel (4%), fresh whole Pacific hake (4%), fresh turkey liver (4%), fresh chicken heart (4%), chicken (dehydrated, 4%), turkey (dehydrated, 4%), whole mackerel (dehydrated, 4%), whole sardine (dehydrated, 4%), whole herring (dehydrated, 4%), Alaskan pollock (dehydrated, 4%), lentil fibre, whole red lentils, whole green lentils, fresh whole green peas, fresh whole chickpeas, fresh whole yellow peas, whole pinto beans, whole navy beans, chicken cartilage (dehydrated, 1%), fresh turkey heart (1%), apple fibre, dried algae (source of DHA and EPA), pumpkin (dehydrated), butternut squash (dehydrated), carrots (dehydrated), chicken liver (freeze-dried), turkey liver (freeze-dried), fresh whole pumpkin, fresh whole butternut squash, fresh whole zucchini, fresh whole parsnips, fresh carrots, fresh whole Red Delicious apples, fresh whole ...
Use of Cell Salvage Post-operatively in Infants to Decrease Use of Allogeneic Blood Product Transfusions - Full Text View -...
Transfusion of washed intra-operative cell salvage post-operatively in the PCICU can be performed safely without increased risk of bleeding or release of inflammatory mediators. This will reduce the need for allogeneic blood products as well as crystalloid and colloid infusions and thus decrease the length of ventilation and intensive care duration for these infants ...
Overuse of blood transfusions increases infection risk | Veterinary Sciences Tomorrow
by Vetscite. Blood transfusions are one of the most common procedures patients receive in the hospital but the more red blood cells they receive, the greater their risk of infection, says a new study led by the University of Michigan Heath System and VA Ann Arbor Healthcare System. Researchers analyzed 21 randomized controlled trials for the study that appears in Journal of the American Medical Association (JAMA). Elderly patients undergoing hip or knee surgeries were most susceptible, with a 30 percent lower risk of infection when fewer transfusions were used. Overall, for every 38 hospitalized patients considered for a red blood cell transfusion (RBC), one patient would be spared a serious infection if fewer transfusions were used. Transfusions are often used for anemia or during surgery to make up for blood loss. The authors evaluated all health care-associated infections that were reported after receiving donor blood in the randomized trials. These included serious infections such as ...
Blood Transfusion in Resource-limited Settings | Anesthesiology | ASA Publications
As French physicians frequently and currently deployed in Theater of Operations in Africa, we read with interest the article by Ariyo et al.1 reviewing the anesthesia care provided at Médecins Sans Frontières facilities between 2008 and 2014. Spinal anesthesia was the most common type of anesthetic technique (34,413 [45.56%]), with cesarean section being the most common type of procedure performed (26,091 [34.54%]). Wound surgeries represented another common procedure type included in this retrospective study (18,547 [24.55%]). In this context, perioperative deaths occurred in 72 (0.21%) cases of obstetrics/gynecology and urology surgery and in only seven (0.06%) cases of wound surgeries. Nevertheless, the authors did not provide any details regarding the causes of death or any details about the incidence of perioperative bleeding and perioperative blood management. Perioperative blood management refers to perioperative blood transfusion and adjuvant therapies.2 Perioperative blood transfusion ...
Orijen Six Fish Dry Cat Food
Fresh whole pacific pilchard (26%), fresh whole pacific hake (9%), fresh whole pacific mackerel (8%), fresh whole pacific flounder (5%), fresh whole rockfish (5%), fresh whole sole (5%), whole mackerel (dehydrated, 5%), whole herring (dehydrated, 5%), whole blue whiting (dehydrated, 5%), herring oil (5%), alaskan cod (dehydrated, 5%), whole red lentils, whole green lentils, whole green peas, sunflower oil (cold-pressed), whole sardines (dehydrated, 1.5%), lentil fiber, whole chickpeas, whole yellow peas, whole pinto beans, cod liver (freeze-dried), fresh whole pumpkin, fresh whole butternut squash, fresh whole zucchini, fresh whole parsnips, fresh carrots, fresh whole red delicious apples, fresh whole bartlett pears, fresh kale, fresh spinach, fresh beet greens, fresh turnip greens, brown kelp, whole cranberries, whole blueberries, whole saskatoon berries, chicory root, turmeric root, milk thistle, burdock root, lavender, marshmallow root, rosehips, enterococcus faecium.. ADDITIVES (per kg): ...
Abstract 14026: The Impact of Hemoglobin Drop, Bleeding Events and Blood Transfusion on Long Term Mortality Following...
Background: Despite the minimally invasive nature of trans-catheter aortic valve implantation (TAVI), the procedure is associated with several complications. We analyzed the individual impact of bleeding events, hemoglobin (Hb) drop, and Red Blood Cells (RBC) transfusions on prognosis.. Methods and results: Consecutive patients (n=597) undergoing trans-femoral TAVI were prospectively enrolled. Peri-procedural Hb levels, RBC transfusions and major/life threatening bleeding events were documented and analyzed. To study the relationship between Hb drop, RBC transfusions and long-term mortality, the entire cohort was divided into 4 groups according to Hb drop (less or ≥ than 3 g/dl), and receiving RBC transfusion (yes /no). In the entire cohort mean Hb level decreased following TAVI (11.8±1.4 to 9.5 ±1.3 g/dl; p,0.001). Major/ life threatening bleedings occurred in 66 (10.1%) patients, and 179 (30%) patients received RBC transfusions. Major/life threatening bleedings were not independently ...
Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B...
We measured antibody (anti-HCV) to hepatitis C virus, which causes non-A, non-B hepatitis, by radioimmunoassay in prospectively followed transfusion recipients and their donors. Of 15 patients with chronic non-A, non-B hepatitis documented by liver biopsy, all seroconverted for the antibody; of 5 with acute resolving non-A, non-B hepatitis, 3 (60 percent) seroconverted. The development of anti-HCV was delayed (mean delay, 21.9 weeks after transfusion, or 15 weeks after the onset of clinical hepatitis) and took approximately one year in one patient. Antibody has persisted in 14 of the 15 patients with chronic disease (mean follow-up, greater than or equal to 6.9 years; maximum, greater than or equal to 12), but has disappeared in the 3 with acute resolving disease after a mean of 4.1 years. Anti-HCV was detected in samples of donor serum given to 14 (88 percent) of the 16 anti-HCV-positive patients for whom all donor samples were available. Only 33 percent of the anti-HCV-positive donors tested ...
ORIJEN Dog & Cat Food | Nourish Your Pet As Nature Intended
Fresh chicken meat (13%), fresh cage-free eggs (7%), fresh turkey meat (7%), fresh whole herring (7%), fresh chicken liver (6%), fresh whole flounder (4%), fresh turkey liver (4%), fresh chicken necks (4%), fresh chicken heart (4%), fresh turkey heart (4%), chicken (dehydrated, 4%), turkey (dehydrated, 4%), whole mackerel (dehydrated, 4%), whole sardine (dehydrated, 4%), whole herring (dehydrated, 4%), whole red lentils, whole green lentils, fresh whole green peas, lentil fibre, fresh whole chickpeas, fresh whole yellow peas, whole pinto beans, fresh chicken cartilage (1%), whole navy beans, herring oil (1%), chicken fat (1%), fresh turkey cartilage (1%), chicken liver (freeze-dried), turkey liver (freeze-dried), fresh whole pumpkin, fresh whole butternut squash, fresh whole zucchini, fresh whole parsnips, fresh carrots, fresh whole Red Delicious apples, fresh whole Bartlett pears, fresh kale, fresh spinach, fresh beet greens, fresh turnip greens, brown kelp, whole cranberries, whole ...
Blood, glorious blood: are attitudes to blood transfusions for palliative purposes always positive? | BMJ Supportive &...
Conclusions There is a lack of current guidelines outlining when to give terminally ill cancer patients a blood transfusion, due to the fact that every patient needs to be individually assessed. Generally, attitudes towards blood transfusions were positive; most thought that suffering was an appropriate reason for a blood transfusion. The large majority did not think that blood transfusions should be withheld. Attitudes towards blood transfusions with palliative intent were slightly more positive in oncology compared to palliative care healthcare professionals.. ...
Publications | University of Nairobi Personal Websites
BACKGROUND: Open simple prostatectomy has long been associated with large blood losses; hence allogeneic blood transfusion in this procedure is a standard practice world over. A review of literature suggests significant association between perioperative blood loss accompanying open simple prostatectomy and certain patient factors. The shortage of blood and blood products in our blood transfusion centres as well as the alarming risks of transfusion reactions and disease dissemination demanded a review of these factors with the aim of reducing morbidity associated with peri-operative blood loss and blood transfusion. OBJECTIVES: To assess blood loss, determine blood transfusion rate, and define some of the factors associated with peri-operative blood loss and blood transfusion in open simple prostatectomy. DESIGN : A prospective cohort study. SETTINGS: The urology units of Kenyatta National Hospital, Kenya. RESULTS: Ninety five patients who underwent open simple prostatectomy for benign prostatic ...
Improving Blood Transfusion Consent - Mediware Information Systems
Some time ago my delightful 80+ year-old grandmother was diagnosed with a GI bleed that led to hospitalization and multiple transfusions. As I am the only nurse in the family, she made a point to tell me that she needed blood because her hemoglobins were low.. I quickly determined that she had no idea what hemoglobin was but she was confident her transfusion therapy was necessary because her trusted family physician had told her that her hemoglobins were low. During her admission, she signed without reading a general treatment consent that included a paragraph about blood transfusion. My grandmother was not told that there are risks associated with allogeneic transfusion nor was any alternative therapy offered. However, she believed that she was receiving appropriate medical care and she had no apparent adverse events with her hospitalization. Was my grandmother given adequate information to make an informed choice about her medical care? Did her physician and hospital meet minimum legal and ...
Ensemble learning approaches to predicting complications of blood transfusion<...
TY - GEN. T1 - Ensemble learning approaches to predicting complications of blood transfusion. AU - Murphree, Dennis. AU - Ngufor, Che. AU - Upadhyaya, Sudhindra. AU - Madde, Nagesh. AU - Clifford, Leanne. AU - Kor, Daryl J. AU - Pathak, Jyotishman. PY - 2015/11/4. Y1 - 2015/11/4. N2 - Of the 21 million blood components transfused in the United States during 2011, approximately 1 in 414 resulted in complication . Two complications in particular, transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO), are especially concerning. These two alone accounted for 62% of reported transfusion-related fatalities in 2013 . We have previously developed a set of machine learning base models for predicting the likelihood of these adverse reactions, with a goal towards better informing the clinician prior to a transfusion decision. Here we describe recent work incorporating ensemble learning approaches to predicting TACO/TRALI. In particular we describe ...
Could Waiting Two Minutes Improve How Newborns Recover from Heart Surgery? - Healthcanal.com : Healthcanal.com
Most physicians typically clamp and cut the umbilical cord immediately following delivery. Some physicians advocate for delaying the clamping of the babys umbilical cord, thereby increasing the flow of blood from the placenta to the child. The practice of delayed umbilical cord clamping has been shown to improve hematocrit levels, leading to an increased number of oxygen-carrying red blood cells throughout the body.. Hematocrit levels are an important factor during surgery and blood transfusions are often required to replace blood lost during complicated procedures. This is especially true in children with critical congenital heart disease.. Babies born with critical congenital heart disease often require multiple blood transfusions during corrective heart surgery due to the complexity of the surgery and the babies small size, said Carl Backes, Jr., MD, Neonatology fellow at Nationwide Childrens Hospital. However, data suggests that surgical outcomes are improved when fewer blood ...
Is Cross Matching Beneficial Prior to the First Blood Transfusion in Cats? - General - News - Research - Royal Veterinary...
Published: 18 Jan 2017 , Last Updated: 18 Jan 2017 08:49:11 Karen Humm (Lecturer in Emergency and Critical Care) has been awarded a grant by Pet Plan for the following project: Is Cross Matching Beneficial Prior to the First Blood Transfusion in Cats? As veterinary practice has advanced, there has been a steady increase in the need for blood transfusions to help cats with a variety of diseases. However, identifying suitable blood donors and obtaining blood from healthy cats in a timely manner is extremely challenging. In situations when a cat has had a previous blood transfusion, it is recommended that prior to any subsequent transfusion a crossmatch screening test is performed. This is how we check that donor blood and patient blood are compatible. If no reaction is seen in this test, the donor is considered suitable and this should decrease the risk of the recipient having a reaction to the blood. A recent study of cats reported that administration of crossmatch compatible blood transfusions ...
Reducing Blood Transfusion Risk and Costs with Advanced CDS | Allscripts
Allscripts is an industry leader in EHR and EMR software. Learn more about Reducing Blood Transfusion Risk and Costs with Advanced CDS
Transfusion-transmitted malaria in Ghana. - Surrey Research Insight Open Access
BACKGROUND: In sub-Saharan Africa, the prevalence of malaria parasitemia in blood donors varies from 0.6% to 50%. Although the burden of TTM in malaria-endemic countries is unknown, it is recommended that all donated blood is screened for malaria parasites. This study aimed to establish the incidence of TTM and identify a suitable screening test. METHODS: Pregnant women, children, and immunocompromised malaria-negative transfusion recipients in a teaching hospital in Ghana were recruited over the course of 1 year. Parasites detected in recipients within 14 days of the transfusion were genotyped and compared to parasites in the transfused blood. The presence of genotypically identical parasites in the recipient and the transfused blood confirmed transfusion-transmitted malaria. Four malaria screening tests were compared to assess their usefulness in the context of African blood banks. RESULTS: Of the 50 patients who received transfusions that were positive for Plasmodium falciparum by polymerase ...
Acute effects of blood transfusion on pituitary gonadal axis and sperm parameters in young males with sickle cell disease (SCD)...
Objective: To evaluate semen parameters and measure serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (T) concentrations before and 7 days after packed red cell transfusion (PCTx) in adults with sickle cell disease (SCD). Methods: This prospective study investigated 18 young adults with transfusion-dependent SCD, aged 20.7 +/- 2.88 years, with full pubertal development (Tanner's stage 5) (euogonadal), and capacity to ejaculate. Their serum ferritin levels were 1488 +/- 557ng/ml. Basal serum concentrations of FSH, LH, T and IGF-I were evaluated before and 7 days after packed red cell transfusion (PCTx). We studied the effect of PCTx on semen parameters and the endocrine functions in these 18 patients with SCD. Results: Following PCTx, a significant increase of Hb from 8.5 +/- 1.17 g/dl to 10.5 +/- 0.4 g/dl was associated with increased testosterone (12.3 +/- 1.24 nmol/L to 14.23 +/- 1.22nmol/L and gonadotropin concentrations. Total sperm count increased
Monitoring and reporting transfusion reactions as a quality indicator
Abstract:. BACKGROUND AND OBJECTIVE: This audit was conducted as a part of a quality assurance activity to assess the frequency of receiving completely filled out blood transfusion reaction forms which were accompanied by the required samples. Once this information is known, we will elevate the bar each year to achieve 100% compliance. The sub-aim was to evaluate the frequency of the reported transfusion reactions.. MATERIALS AND METHODS: The study was conducted from 1st April 2010 to 30th April 2011. The information was evaluated and the frequency of receiving completely filled blood transfusion reaction forms was assessed. The variables identified were the type of transfusion reaction, the blood component transfused, the health care personnel filling the form, and whether there was legible handwriting and a completely filled form. Transfusion reactions were reported as a percentage of the total number of units transfused.. RESULTS: During the study period, 17,880 packed red cells, 13,200 ...
Blood School: Building a Foundation for Transfusion Safety
This program will review the creation and benefits of Blood School, an eight-hour introductory course on transfusion safety for nurses. Recognizing that primary blood transfusion education was too procedure-centric, this course was developed as a supplement to provide education on the core foundations of transfusion medicine. Blood School uses a combination of didactic and active learning approaches, in order for the participants to feel more knowledgeable, comfortable, and safer with all transfusion-related processes. In doing so, it empowers them to be better advocates for patients, take action whenever they recognize negative situations related to blood transfusions, and help ensure that the right patient gets the right blood component for the right reason in the safest way. ...
WHO | 10 facts on blood transfusion
Often transfusions are prescribed when simple and safe alternative treatments might be equally effective. As a result such a transfusion may not be necessary. An unnecessary transfusion exposes patients to the risk of infections such as HIV and hepatitis and adverse transfusion reactions.. ...
Moderate Exposure to Allogeneic Blood Products Is Not Associated with Reduced Long-term Survival after Surgery for Coronary...
There have been previous studies with similar hypotheses and methodology. Engoren et al. 12 studied 1,915 subjects undergoing first-time isolated coronary artery bypass at St. Vincent Mercy Medical Center, Toledo, Ohio. In a Cox regression model, they demonstrated that age, New York Heart Association functional class IV, chronic obstructive pulmonary disease, peripheral vascular disease, and perioperative blood transfusion were predictors of mortality occurring between 1 and 5 yr after surgery. Detailed information about the number of units transfused was not available; therefore, quantification of transfusion was done in a limited manner, subjects were grouped according to transfusions given during the intraoperative period, postoperative period, or both. Koch et al. 13 studied 10,289 subjects undergoing isolated coronary artery surgery at the Cleveland Clinic, follow-up was 10 yr, and transfusion was quantified by the number of units of red cells transfused to subjects in the perioperative ...
Blood Transfusion Sets - Blood Transfusion Sets Suppliers, Buyers, Wholesalers and Manufacturers - ecplaza.net
Blood Transfusion Sets directory ☆ Blood Transfusion Sets manufacturers, suppliers ☆ Blood Transfusion Sets buyers, importers, wholesalers, distributors
23 Indian kids get HIV from blood vessels transfusions AHMADABAD.
When we proceeded to go for transfusion on August 9, the doctors asked us to obtain the HIV test done. The result was positive, Sheikh told the paper. The doctors, blood bank staff and medical center superintendent said, It provides happened, what you can do? Sheikh sold his motorbike and television to pay for his daughters monthly blood transfusions and medicines.. 23 Indian kids get HIV from blood vessels transfusions AHMADABAD, India - At least 23 children suffering from a rare genetic disorder that will require regular blood transfusions possess tested positive for HIV after receiving tainted blood, officials said Monday. The children, who have problems with thalassemia and so are from poor households, all received free bloodstream transfusions at a government-run medical center in the Junagadh district of Gujarat state in western India between January and August, hospital mind G.T.. One in four people in Asia will be 60 or older by the year 2050, rising from one in 10 this year 2013, ...
ISBT: Paediatric Subgroup of the Clinical Transfusion and Haemovigilance Working Parties
Substantial variability in practice exists in clinical transfusion, patient blood management and blood conservation in paediatrics. Neonates and children are frequently transfused patient populations, yet they are relatively under-represented in clinical trials and the evidence-base to guide practice is limited. A number of clinical practices are extrapolated from the results of adult studies. Yet neonates and children have unique pathophysiology, specific vulnerabilities and different risk profiles compared to adult transfusion recipients. A disproportionate number of transfusion adverse events are reported in the neonatal and paediatric age groups. Any adverse outcome related to transfusion is particularly important in these young recipients, as most are anticipated to live for many years post transfusion. Transfusion decision making in paediatrics needs to consider the potential risks and benefits of a transfusion and any alternatives to transfusion. ...
Had severe blood transfusion reaction, wonder which type? -Doctors Lounge(TM)
I have anemia and needed a blood transfusion and attempted my first transfusion last week. After about a tablespoon of blood went into my IV, my vision grayed out and I dont remember what happened next. I was told I had chills, diaphoresis, decreased level of consciousness, eyes rolling back in head and woke up so to speak, vomiting. What happened to me? They said I had no fever but had a severe transfusion reaction. I received Benadryl and Solu-Medrol and a bag of fluid after that. They had stopped the blood when I came to and said my blood pressure had dropped to 70/40 and my pulse had dropped. My family doctor was called and diagnosed it as a vasovagal reaction. Can a severe blood transfusion reaction be called a vasovagal reaction? They said there was no hemolyzation of the blood. What exactly happened? How often does this happen? They gave me another unit with the premedication and filter, and it seemed to work okay that time. What do I need to understand about what happened ...
Iatrogenic hemodilution: a possible cause for avoidable blood transfusions? | Critical Care | Full Text
In one of the largest randomized controlled trials (RCTs) on GDT, the incidence of blood transfusions was double (22 vs 11%) in the GDT group patients, who received nearly twice the amount of colloids compared to the control group, even though the same transfusion threshold (Hb , 8 g/dl) was used for both groups . The most feasible explanation for this clinically relevant and statistically significant difference (p = 0.04 based on a chi square test), which was not calculated nor discussed in the article , is that more patients in the GDT group reached Hb levels below the transfusion threshold due to hemodilution, prompting physicians to order blood transfusions. Other RCTs have also reported that patients in the GDT group, who received significantly more colloid boluses, received significantly more blood transfusions [12, 13] and had significantly higher blood loss  compared to the standard therapy group. In another study, the administration of more colloids led to lower Hb and DO2 ...
Defining transfusion triggers and utilization of fresh frozen plasma and platelets among patients undergoing...
TY - JOUR. T1 - Defining transfusion triggers and utilization of fresh frozen plasma and platelets among patients undergoing hepatopancreaticobiliary and colorectal surgery. AU - Ejaz, Aslam. AU - Frank, Steven M.. AU - Spolverato, Gaya. AU - Kim, Yuhree. AU - Pawlik, Timothy M.. PY - 2015/1/1. Y1 - 2015/1/1. N2 - Background: We sought to define the overall utilization of fresh frozen plasma (FFP) and platelets and the impact on perioperative outcomes among patients undergoing hepatopancreaticobiliary and colorectal resections, as well as analyze the utility of laboratory triggers in guiding transfusion practice. Methods: We identified 3027 patients undergoing pancreatic, hepatic, and colorectal resections between 2010 and 2013 at Johns Hopkins Hospital. Data on international normalized ratio (INR) and platelet counts that triggered the perioperative utilization of these non-RBC (red blood cell) products were obtained and analyzed. Results: Overall FFP and platelet transfusion rates were 8.9% ...
A Risky Proposition: Blood Transfusion and the Risk of Surg... : Anesthesia & Analgesia
In our perpetually evolving pursuit to optimize the risk-benefit profile of perioperative interventions, the decision to administer allogeneic blood products is fraught with extraordinarily conflicting goals. This infographic summarizes the results of a retrospective analysis that examines the relationship between perioperative blood transfusion and infectious complications. Superficial and deep incisional infections appear not to be influenced whereas organ space infections and septic shock are associated with the administration of blood products.. CI indicates confidence interval; NSQIP, National Surgical Quality Improvement Program; OR, odds ratio; RBC, red blood cell. ...
Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects - Full Text View - ClinicalTrials.gov
About 100 patients aged several months to 50 years are treated in the Pediatric Hematology Unit, most of those patients receive blood transfusions monthly. The adverse reactions were routinely recorded during each transfusion. All the patients were also screened annually for the incidence of blood transmitted infections principally HIV and Hepatitis C. All those records will be systematically screened and all the immediate or late adverse reactions and complications related to blood transfusions will be summarized.. A second goal of this study will be to control the staff strictness related to the ministry of health protocol dealing to blood transfusions. ...
Economic Impact of Blood Transfusion in Selected Open and Laparoscopic Abdominal Surgical Procedures in the USA - SAGES...
Santosh J Agarwal, BPharm MS, Alexandra A MacLean, MD, Gary V Delhougne, JD MHA, Ned Cosgriff, MD, Ross D Segan, MD FACS. Covidien. Objective: The objective of this study was to examine the incidence of blood transfusion in selected open and laparoscopic abdominal surgical procedures and evaluate the impact of transfusion on hospitalization costs and length of hospital stay.. Methods: The Premier PerspectiveTM Database (PPD) was used to identify open and laparoscopic appendectomy, cholecystectomy, colectomy and Roux-en-Y gastric bypass surgical procedures in 2009. PPD is the largest hospital-based comparative database providing detailed resource utilization and cost data. Combinations of ICD9 and CPTTM codes were used to identify patients with blood transfusion(s). We compared the incidence of blood transfusion, mortality rates, total hospitalization costs and hospital length of stay (LOS) among selected open and laparoscopic procedures. Multivariate regression analysis was used to predict the ...
Massive transfusion - Oxford Medicine
♦ Treatment of anaemia has changed substantially since the early 1990s♦ Although massive transfusion may be necessary, trauma surgeons have modified their practice to provide aggressive control of haemorrhage, prevent hypothermia and acidosis, optimize haemodynamic management in intensive care units, and rationalize transfusion support in severely injured patients. The result has been an improvement in the outcomes of these patients♦ Given the importance of early intervention in the care of the injured, understanding the physiology and true indications for early massive transfusion in trauma care has the potential to save many lives.
Leukemia, on blood transfusions, swelling in the legs, myelodysplasia
Question - Leukemia, on blood transfusions, swelling in the legs, myelodysplasia . Ask a Doctor about diagnosis, treatment and medication for Arthritis, Ask an Oncologist
Questions About the Watchtowers View on Blood Transfusions. (page 3)
i admit to not being very well informed about the watchtowers view on blood transfusions. i have a couple of questions that i hope someone here is able to answer.. i understand that the watchtower now considers it to be okay to receive blood fractions.. my first question is: are all fractions considered to be permissible? and if not, specifically which fractions are not permissible?.
Doctors are still working on a cure for MDS, though there are many ways to manage the disease. Patients with very low risk who do not need blood transfusions may be able to go without treatment for years, as long as they are checked regularly by a doctor. Other patients need more aggressive therapies. One treatment regimen that has worked for some patients is high doses of chemotherapy followed by a stem cell transplant. Other MDS treatments aim to reduce the need for blood transfusions, decrease the risk of infection and increase quality of life.. Blood transfusions - Some patients may need red cell to relieve symptoms of fatigue and shortness of breath. Blood transfusions increase the number of normal red blood cells in circulation, helping to relieve anemia. Platelet transfusions may be given to prevent or stop bleeding if platelet counts are very low.. During a transfusion, a technician will hang a bag containing the blood product you are receiving from a pole, then insert a narrow tube into ...
Cardiovascular responses to blood transfusion in children with anemic heart failure. - Semantic Scholar
INTRODUCTION This study evaluated the cardiovascular responses to blood transfusion in children with anemic heart failure using mostly clinical parameters. MATERIALS AND METHODS Consecutive patients with anemic heart failure presenting to a childrens emergency room and requiring blood transfusion were assessed for heart rate (HR), respiratory rate (RR), systolic blood pressure (SBP), liver size, and oxygen saturation (O 2 sat) pre-transfusion, 1-2 h into transfusion (intra-transfusion), immediate post-transfusion, and at late post-transfusion (24 h later). RESULTS A total of 75 patients were recruited of which 46 (61.3%) were males. Their mean age was 43.8 ± 40.3 months while their mean PCV at presentation was 15.0 ± 4.5%. There was a significant mean net reduction of 10 beat per minute (bpm) between the pre (139.7 ± 25.2 bpm) and intra-transfusion (129.6 ± 22.0 bpm) HR, P = 0.0004. The mean net reduction of 4 cycles/ min between the pre and intra-transfusion RR was also significant, P = 0.0033
DI-fusion Multiple transfusions and T cell subsets: A role for ferritin?
DI-fusion, le Dépôt institutionnel numérique de lULB, est loutil de référencementde la production scientifique de lULB.Linterface de recherche DI-fusion permet de consulter les publications des chercheurs de lULB et les thèses qui y ont été défendues.
This clinic offers Pre-operative Blood Conservation Strategies for Adults.. The Blood Conservation Coordinator is located on the 3rd Floor in the Ambulatory Care area of the Carlo Fidani Building. Adults requiring surgery who are interested in avoiding blood transfusion may make an appointment directly by calling (905) 813-1100 ext. 5540. You must be having surgery at Credit Valley, or have a family doctor affiliated with Credit Valley Hospital. Alternatively, your doctor can also make the referral for you.. Many blood transfusions associated with elective surgery can be avoided through advanced planning and preparation, if there is sufficient time before surgery. Once you know that you are having surgery in the future, it may be important to ask your doctor for a blood test to determine your hemoglobin level. Generally, the higher your iron or hemoglobin level the less chance of requiring a blood transfusion during your surgical hospital stay. Not all surgeries result in a transfusion risk, so ...
Girl in China got HIV through blood transfusion: Report | Health News
A five-year-old girl in China contracted HIV through a blood transfusion, state media reported, the latest case to shine a light on an issue that has long bedevilled the country.
Intrauterine Fetal Blood Transfusion for Rh Disease
An intrauterine transfusion provides blood to an Rh-positive fetus when fetal red blood cells are being destroyed by Rh antibodies.. A blood transfusion is given to replace fetal red blood cells that are being destroyed by the Rh-sensitized mothers immune system. This treatment is meant to keep the fetus healthy until he or she is mature enough to be delivered.. Transfusions can be given through the fetal abdomen or, more commonly, by delivering the blood into the umbilical vein or artery. Umbilical cord vessel transfusion is the preferred method, because it permits better absorption of blood and has a higher survival rate than does transfusion through the abdomen.footnote 1. An intrauterine fetal blood transfusion is done in the hospital. The mother may have to stay overnight after the procedure.. ...
Effect of blood transfusion on recurrence of head and neck carcinoma : retrospective review and meta-analysis. | Base...
To study the effect of transfusion on recurrence of squamous cell carcinoma of the head and neck, we analyzed the records of 143 patients with stage 11 through N squamous cell carcinoma of the supraglottic larynx or hypopharynx for whom follow-up to recurrence or 5 years after surgical therapy was available. Variables studied were age, gender,...
Blood product utilisation during massive transfusions: audit and review of the literature
VISSER, Adele et al. Blood product utilisation during massive transfusions: audit and review of the literature. SA orthop. j. [online]. 2011, vol.10, n.4, pp.25-29. ISSN 2309-8309.. Acute exsanguination is the leading cause of mortality in trauma patients.1-3 Massive blood loss potentially results in the development of the lethal triad, comprising hypothermia, acidosis and coagulopathy.4 Without prompt intervention, including the appropriate administration of blood and blood products, the majority of these patients will demise within 6 hours.2,4,5 Utilisation of blood and blood products in this setting is considered a lifesaving intervention. A massive transfusion can be defined as the 1) the infusion of five units or more of packed red cell concentrate (RCC) within 4 hours;6 2) infusion of more than ten units RCC within the first 24 hours;7-15 or 3) infusion of six or more units RCC within 12 hours.16-18 Irrespective of the formal definition, it has become evident that patients requiring six ...
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Results of a protocol of transfusion threshold and surgical technique on transfusion requirements in burn patients<...
TY - JOUR. T1 - Results of a protocol of transfusion threshold and surgical technique on transfusion requirements in burn patients. AU - OMara, Michael S.. AU - Hayetian, Fernando. AU - Slater, Harvey. AU - Goldfarb, I. William. AU - Tolchin, Eric. AU - Caushaj, Philip F.. PY - 2005/8/1. Y1 - 2005/8/1. N2 - Introduction: Blood loss and high rates of transfusion in burn centers remains an area of ongoing concern. Blood use brings the risk of infection, adverse reaction, and immunosuppression. Methods: A protocol to reduce blood loss and blood use was implemented. Analysis included 3-year periods before and after institution of the protocol. All patients were transfused for a hemoglobin below 8.0 gm/dL. Results: Operations per admission did not change during the two time periods (0.78 in each). Overall units transfused per operation decreased from 1.56 ± 0.06 to 1.25 ± 0.14 units after instituting the protocol (p , 0.05). Also, units transfused per admission decreased from 1.21 ± 0.15 to 0.96 ...
Transfusions of blood components are often necessary for the patient to complete the planned cancer treatment.. Blood transfusions are appropriate for low hemoglobin (Hb) and thrombocyte transfusions for low thrombocytes (trc) which also poses a risk for serious bleeding.. ...
Difference between revisions of Transfusion-related acute lung injury - WikEM
Recipient factors,ref,Vlaar AP, et al. Risk factors and outcome of transfusion-related acute lung injury in the critically ill: a nested case-control study. Crit Care Med. 2007;176:886,/ref,,ref,Gajic O, et al. Transfusion-related acute lung injury in the critically ill: prospective nested case-control study. Am J Respir Crit Care Med. 2007;176:886,/ref,,ref name=fifteen,Toy P, et al. Transfusion-related acute lung injury: incidence and risk factors. Blood. 2012;119:1757,/ref,,ref,Benson AB, et al. Transfusion-related acute lung injury in ICU patients admitted with gastrointestinal bleeding. Intensive Care Med. 2010;36:1710,/ref ...
Difference between revisions of Transfusion-related acute lung injury - WikEM
Non-critically ill with TRALI - 5-7% ,ref,Looney MR, et al. Prospective study on the clinical course and outcomes in transfusion-related acute lung injury. Crit Care Med. 2014;42:1676,/ref,,ref,Popovsky MA, et al. Transfusion-related acute lung injury: a neglected serious complication of hemotherapy. Transfusion. 1992;32:589,/ref,,ref,Sillman CC, et al. Transfusion-related acute lung injury (TRALI): current concepts and misconceptions. Blood Rev. 2009;23:245,/ref ...
The efficiency of hemodialysis in transfusion-related acute lung injury (TRALI): A case report [Eastern J Med]
Transfusion-Related Acute Lung Injury (TRALI) is an important life-threatening complication that is related with blood transfusion. The frequency is reported as 1/5.000. It is generally characterized with hypoxia that appears at the 2-6th hours after the blood transfusion, bilateral infiltration in the chest radiography, and non-cardiogenic pulmonary edema. Acute respiratory distress, hypotension, tachycardia and fever accompany the clinical picture. Past surgery, blood transfusion, and sepsis are among the factors that trigger the disease. In this study, the efficiency of the hemodialysis applied in the right time in the treatment of a heavy TRALI case developed after a blood transfusion has been presented.. Keywords: Acute lung injury, efficiency, hemodialysis, ...
Detection of homologous blood transfusion - DSHS
TY - JOUR. T1 - Detection of homologous blood transfusion. AU - Voß, Sven. AU - Thevis, Mario. AU - Schinkothe, T.. AU - Schänzer, Wilhelm. PY - 2007. Y1 - 2007. N2 - The aim of the present study was to improve and validate a flow cytometric method for the detection of homologous blood transfusion in doping control analysis. A panel of eight different primary antibodies and two different phycoerythrin-conjugated secondary antibodies was used for the detection of different blood populations. The flow cytometer used in this study was the BD FACSArray® instrument. Mixed red blood cell populations were prepared from phenotype known donors. Linearity, specificity, recovery, precision, robustness and interday-precision were tested for every primary antibody used in the presented assay. The technique of signal amplification was utilized for an improved separation of antigens with weak or heterozygous expression to improve the interpretation of histograms. The resulting method allowed to clearly ...
Delayed hemolytic transfusion reaction - Wikipedia
A delayed hemolytic transfusion reaction (DHTR) is a type of transfusion reaction. It is defined as fever and other symptoms/ signs of hemolysis more than 24 hours after transfusion; confirmed by one or more of the following: a fall in haemoglobin (Hb) level or failure of Hb level to rise after transfusion rise in bilirubin (jaundice) incompatible crossmatch not detectable pre-transfusion. This can occur up to four weeks after the transfusion. Delayed blood transfusion reaction occurs more frequently (1 in 20,569 blood components transfused in the USA in 2011) when compared to acute haemolytic transfusion reaction. One way this can occur is if a person without a Kidd blood antigen receives a Kidd antigen in a transfusion. Other common blood groups with this reaction are Duffy and Kell. Noizat-Pirenne F, Bachir D, Chadebech P, et al. (December 2007). Rituximab for prevention of delayed hemolytic transfusion reaction in sickle cell disease. Haematologica. 92 (12): e132-5. ...
Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with...
Many people diagnosed with haematological malignancies experience anaemia, and red blood cell (RBC) transfusion plays an essential supportive role in their management. Different strategies have been developed for RBC transfusions. A restrictive transfusion strategy seeks to maintain a lower haemoglobin level (usually between 70 g/L to 90 g/L) with a trigger for transfusion when the haemoglobin drops below 70 g/L), whereas a liberal transfusion strategy aims to maintain a higher haemoglobin (usually between 100 g/L to 120 g/L, with a threshold for transfusion when haemoglobin drops below 100 g/L). In people undergoing surgery or who have been admitted to intensive care a restrictive transfusion strategy has been shown to be safe and in some cases safer than a liberal transfusion strategy. However, it is not known whether it is safe in people with haematological malignancies.To determine the efficacy and safety of restrictive versus liberal RBC transfusion strategies for people diagnosed with
Transfusion-related acute lung injury: epidemiology and a prospective analysis of etiologic factors | Blood | American Society...
Transfusion-related acute lung injury (TRALI) is a life-threatening complication of hemotherapy. We report a series of 90 TRALI reactions in 81 patients seconda
Revisiting acute normovolemic hemodilution and blood transfusion during pediatric cardiac surgery: a prospective observational...
Children undergoing cardiac surgery with cardiopulmonary bypass (CPB) are at high risk of being exposed to relatively large volumes of allogeneic blood products. If blood transfusion can be life-saving in some circumstances (e.g. major haemodilution or massive haemorrhage), the administration of large volumes of allogeneic blood products has been shown to significantly increase the risk of postoperative complications. Over the last decades, different strategies have been developed to reduce the need for blood product transfusions.. Acute normovolemic hemodilution (ANH) has been used for a long time in adults undergoing high bleeding risk procedures, including cardiac surgery. While some studies reported a decrease in the incidence of transfusion and in the volume of red blood cells transfused, only limited evidence exists in infants and children undergoing cardiac surgery. Major differences exist between children and adults undergoing cardiac surgery, limiting the use of ANH to a small number of ...
Diamond Blackfan Anaemia: Leukaemia Foundation
There are two common forms of treatment:. Steroid therapy: Approximately 70% of people diagnosed with DBA have steroid therapy which improves their anaemia. However, in some cases steroid therapy can stop working and the anaemia may return. Sometimes steroid therapy is used in combination with cyclosporin A. Those who respond to steroid treatment may remain on steroids for the rest of their lives.. Blood transfusions: For those who do not respond to steroid treatment, regular blood transfusions may be required. It is important to note that recipients of regular blood transfusions may be at risk of iron overload*. Iron overload occurs when there is a buildup of iron in the body as a result of blood transfusions. It is important to discuss this with your health care professional.. ...
Blood transfusion service in France completes 20,000 tests and establishes Amorfix EP-vCJD(TM) test
May 20,2009- Blood transfusion service in France completes 20,000 tests and establishes Amorfix EP-vCJD(TM) test in a second blood center.
Does tranexamic acid reduce blood transfusion following surgery for inter-trochanteric fracture? A randomized control trial
Despite having many studies to evaluate the role of TXA in surgeries, limited literature is available on its role in hip fracture surgeries. In an RCT, TXA was administered as an initial bolus dose of 500mg before surgery followed by continuous infusion at 1mg/kg/h for the duration of surgery. Results showed that the differences in mean reduction in Hb and mean volume of blood loss postoperatively between TXA and placebo groups were significant. In addition, only 7 out of 45 patients in TXA group required blood transfusion compared to 18 out of 45 in placebo group and the difference was again significant.5 On the contrary, another RCT in 2010 concluded that there was no significant difference in blood transfusion rates between TXA and placebo groups after surgery for hip fracture.3 Therefore, although effectiveness of TXA in reducing post-surgical blood loss and transfusion requirements have been shown by multiple studies, but its effectiveness, specifically in hip fracture surgeries, is yet to ...
Transfusion medicine has changed blood bank concept: Experts
Bhubaneswar, Dec 21 The concept of the Blood Bank has undergone a sea change over the last three decades and a half with Transfusion Medicine taking over and dealing with the management of blood-related ailments, experts said at a workshop held at the Institute of Medical Sciences and SUM Hospital.. Today immune haematology and transfusion services are inseparable as transfusion medicine encompasses all aspects of transfusion of blood and blood components, Odisha Director, Medical Education and Training Prof. C.B.K.Mohanty said. Maintenance and observation of blood safety were more important, he said, adding a scientific approach to blood transfusion had expanded.. Transfusion medicine, also known as transfusiology, which began in the USA in 1987 is the branch of medicine that is now playing an important role in patient care, he said. (UNI) ...
Platelet Transfusion - Page 4 - Transfusion News
Researchers from the University of Washington and Puget Sound Blood Center have demonstrated that pathogen-reduction may be an effective method to prevent alloimmunization among patients receiving platelet transfusions. The findings were presented at the 54th Annual Meeting of the American Society of Hematology (ASH). Using an immunocompetent dog model, Dr. Sherrill Slichter and colleagues evaluated the impact […]. [Read More] ...
Economic impact of inappropriate blood transfusions in coronary artery bypass graft surgery. | Base documentaire | BDSP
PURPOSE: In addition to histolorically important issues of blood inventory and blood safety, tie costs of blood transfusion are anticipated to have an increasingly important impact on transfusion practices. To address this, the analyzed costs of blood support given to patients undergoing coronary artery bypass graft CABG surgery, along woith...
Liberal vs. Restrictive Transfusion Strategies: Are We Still Following the Results of the TRICC Trial? | Topics in Evidence...
A new randomized multicenter pilot study involving six ICUs in the United Kingdom was recently published in Critical Care Medicine journal.9 The authors in this study compared hemoglobin concentration (Hb), RBC use, and patient outcomes when restrictive or liberal blood transfusion strategies are used to treat anemic (Hb ≤ 90 g/L) critically ill patients of age ≥ 55 years requiring ≥ 4 days of mechanical ventilation in the ICU. One hundred patients were randomized to restrictive transfusion strategy targeting 71-90 g/L (n=51) and to liberal transfusion strategy targeting 91-110 g/L (n=49) for 14 days or the remainder of ICU stay, whichever was longest. ...
Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial...
Transfusion threshold adherence will be described as the proportion of per protocol RBC transfusion events. A transfusion threshold event is defined as an occurrence which starts when a haemoglobin value is measured at or below the allocated threshold for the first time since the previous event and ends when one of the following occurs: (1) an RBC transfusion is administered; or (2) a repeat haemoglobin is obtained above the allocated threshold within 24 hours of the original measure.. Transfusion threshold non-adherence will be considered to have occurred with any of the following: (1) an RBC transfusion occurs before a transfusion threshold is crossed; or (2) in the liberal arm, a transfusion is not given following a threshold crossing. Transfusion threshold non-adherence will be considered a deviation if: (1) the early transfusion occurs within 5 g/L above the allocated threshold (eg, ≤105 g/L for the liberal arm or ≤85 g/L for the restrictive arm) or, (2) in the liberal arm, an RBC ...
Transfusion Medicine - Choosing Wisely Canada
Indications for red blood transfusion depend on clinical assessment and the cause of the anemia. In a stable, non-bleeding patient, often a single unit of blood is adequate to relieve patient symptoms or to raise the hemoglobin to an acceptable level. Transfusions are associated with increased morbidity and mortality in high-risk hospitalized inpatients. Transfusion decisions should be influenced by symptoms and hemoglobin concentration. Single unit red cell transfusions should be the standard for non-bleeding, hospitalized patients. Additional units should only be prescribed after re-assessment of the patient and their hemoglobin value.. Sources:. Bracey AW, et al. Lowering the hemoglobin threshold for transfusion in coronary artery bypass procedures: effect on patient outcome. Transfusion. 1999 Oct;39(10):1070-7. PMID: 10532600.. Carson JL, et al. Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. Cochrane Database Syst Rev. 2012 Apr 18;(4):CD002042. ...
Is Diabetes Contagious Through Blood
Is Diabetes Contagious Through Blood is a thoughtful condition. Learn about Is Diabetes Contagious Through Blood or are you at risk for Is Diabetes Contagious Through Blood. But if you treat it carefully you can provent Is Diabetes Contagious Through Blood. But bont worry about Is Diabetes Contagious Through Blood? Youve come to the right place. This quick guide for Is Diabetes Contagious Through Blood. These technique will get you started.
Blood transfusion | NICE
Why this is important:- Audits have shown that fresh frozen plasma is widely used for non-bleeding patients in the intensive care unit (ICU) and many other clinical settings. There is a large variation in dose and no real evidence base to guide practice. Fresh frozen plasma transfusions may cause adverse outcomes in people who are critically ill, including transfusion-related acute lung injury, transfusion-related circulatory overload, multi-organ failure and an increased risk of infections ...
Better use of blood in Northern Ireland - guidelines for blood transfusion practice
This document contains four guidelines on the following aspects of blood transfusion practice: red cell transfusion; the management of acute massive blood loss; the use of blood components in obstetrics; neonatal transfusion. The guidelines are of relevance to all Northern Ireland GPs who use blood. Audit tools are provided for each guideline. ...
Time Trial Performance Is Sensitive to Low-Volume Autologous Blood Transfusion - Forskning - Region Hovedstaden
PURPOSE: This study tested the hypothesis that autologous blood transfusion (ABT) of ~50% of the red blood cells (RBC) from a standard 450-mL phlebotomy would increase mean power in a cycling time trial. In addition, the study investigated whether further ABT of RBC obtained from another 450-mL phlebotomy would increase repeated cycling sprint ability.. METHODS: In a randomized, double-blind, placebo-controlled crossover design (3-month wash-out), nine highly trained male subjects donated two 450-mL blood bags each (BT trial) or were sham phlebotomized (PLA trial). Four weeks later, a 650-kcal time trial (n = 7) was performed 3 d before and 2 h after receiving either ~50% (135 mL) of the RBC or a sham transfusion. On the following day, transfusion of RBC (235 mL) from the second donation or sham transfusion was completed. A 4 × 30-s all-out cycling sprint interspersed by 4 min of recovery was performed 6 d before and 3 d after the second ABT (n = 9).. RESULTS: The mean power was increased in ...
Measures to prevent transfusion-related acute lung injury (TRALI)
Linköping University, Department of Clinical and Experimental Medicine, Transfusion Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Center for Diagnostics, Department of Clinical Immunology and Transfusion Medicine. ...
United Kingdom Blood Transfusion Services - GOV.UK
The UKBTS is run by the Joint Professional Advisory Committee and is responsible for the dissemination of guidance and best practice on blood transfusion.. ...
JCI - Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury
Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-associated mortality in the US. Previously, we established an immune-mediated TRALI mouse model, wherein mice with cognate antigen were challenged with MHC class I mAb. In this study, when mice housed in a rodent, specific pathogen-free barrier room were challenged with MHC I mAb, there was significant protection from TRALI compared with nonbarrier mice. Priming mice with LPS restored lung injury with mAb challenge. Using TLR4-deficient bone marrow chimeras, the priming phenotype was restricted to animals with WT hematopoietic cells, and depletion of either neutrophils or platelets was protective. Both neutrophils and platelets were sequestered in the lungs of mice with TRALI, and retention of platelets was neutrophil dependent. Interestingly, treatment with aspirin prevented lung injury and mortality, but blocking the P selectin or CD11b/CD18 pathways did not. These data suggest a 2-step mechanism of TRALI: ...
Vascular access device and IV infusion therapy resource
Intravenous literature: Kleinman, S., Grossman, B. and Kopko, P. (2010). A national survey of transfusion-related acute lung injury risk reduction policies for platelets and plasma in the United States. Transfusion. [epub ahead of print] Abstract: BACKGROUND: Little information exists on the specific transfusion-related acute lung injury (TRALI) risk reduction practices used by multiple blood collecting…
Blood transfusions increase the risk of venous thromboembolism following ventral hernia repair | SpringerLink
Background Blood transfusions can affect the clotting cascade, leading to a hypercoagulable state. The association of a venous thromboembolic (VTE) event and perioperative blood transfusion has been...
Blood Transfusion Safety and Risks | Aplastic Anemia and MDS International Foundation
Negative side effects of blood transfusion therapy are uncommon. Blood banks, hospitals, and health-care providers take many precautions to minimize risks before each blood transfusion. Blood banks test each unit of blood to find out its ABO type and Rh status. In the United States, after a hospital laboratory receives a blood unit from the blood bank, the laboratory tests the unit again.
Textbook of Blood Banking and Transfusion Medicine - Elsevier eBook on VitalSource, 2nd Edition - 9781437719895
This comprehensive book on transfusion practices and immunohematology offers concise, thorough guidelines on the best ways to screen donors, store blood components, ensure safety, anticipate the potentially adverse affects of blood transfusion, and more. It begins with the basics of genetics and immunology, and then progresses to the technical aspects of blood banking and transfusion. Chapters are divided into sections on: Basic Science Review; Blood Group Serology; Donation, Preparation, and Storage; Pretransfusion Testing; Transfusion Therapy; Clinical Considerations; and Safety, Quality Assurance, and Data Management. Developed specifically for medical technologists, blood bank specialists, and residents, the new edition conforms to the most current standards of the American Association of Blood Banks (AABB).
Transfusion-associated graft versus host disease - Wikipedia
Transfusion-associated graft-versus-host disease (TA-GvHD) is a rare complication of blood transfusion, in which the donor T lymphocytes mount an immune response against the recipients lymphoid tissue. Donor lymphocytes are usually identified as foreign and destroyed by the recipients immune system. However, in situations where the recipient is immunocompromised (inborn immunodeficiency, acquired immunodeficiency, malignancy), or when the donor is homozygous and the recipient is heterozygous for an HLA haplotype (as can occur in directed donations from first-degree relatives), the recipients immune system is not able to destroy the donor lymphocytes. This can result in graft-versus-host disease. The incidence of TA-GvHD in immunocompromised patients receiving blood transfusions is estimated to be 0.1 - 1.0%, and mortality around 80 - 90%. Mortality is higher in TA-GvHD than in GvHD associated with bone marrow transplantation, where the engrafted lymphoid cells in the bone marrow are of donor ...
Blood transfusion medicine | The BMJ
In the past few years there has been increasing concern about blood transfusion safety. Avoidable transfusion errors, mostly in patient identification, remain a serious cause of injury and death. There is also heightened awareness of the risk of transmission of viral and bacterial infections. Of particular concern in Britain is the (theoretical) possibility of transmission of variant Creutzfeldt-Jakob disease.. This review puts these risks in perspective (table) and describes the new measures that have been introduced to improve blood safety. It also describes changes in attitude and practice that will affect users of blood in all disciplines, including general practitioners advising patients of the pros and cons of transfusion. Finally it emphasises the need for careful education and training of all those involved in blood prescribing and blood component administration. ...
Storage Time of Blood Products and Transfusion-Related Acute Lung Injury - PubMed
While longer storage of buffy coat-derived PLTs was associated with an increased risk of TRALI, storage of plasma for up to 2 years and red blood cells for up to 35 days was not associated with the risk of TRALI.
IMPROVEMENT IN BLOOD TRANSFUSION SERVICE | JAMA Surgery | The JAMA Network
The selection and artificial preparation of high-titered test serums, the study of the cause and prevention of hemolytic transfusion reactions, the consideratio
China Disposable Blood Transfusion Set, Disposable Blood Transfusion Set Manufacturers, Suppliers | Made-in-China.com
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Transfusion-Related Acute Lung Injury (TRALI) | British Society for Haematology
The British Society for Haematology is registered in England and Wales as a Company Limited by Guarantee, No 2645706 and as a Charity, No 1005735 Registered Office and correspondence address: 100 White Lion Street London N1 9PF. Phone: 020 7713 0990 ...
Transfusion-related acute lung injury
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Young Blood and Plasma Transfusions
Young Blood and Plasma Transfusions. The FDA recently warned that plasma infusions from young people provides no proven clinical benefit against normal aging, Alzheimers disease, or a host of other diseases. Directors Gottlieb and Marks from the Center for Biologics Evaluation and Research say young-blood transfusions can pose risks.. Most research thus far into young-blood transfusions has been conducted in mice. Some of the mouse studies have been encouraging, but other studies have been less encouraging. One biotech company is currently testing a plasma-derived product in Alzheimers patients; a previous study from the company yielded mixed results.. One startup company with locations in Los Angeles, San Francisco, Houston, Tampa, Fla., and Omaha, Neb was selling young-blood transfusions at a cost of $8,000 for 1 liter of young blood, or $12,000 for 2 liters. Following a statement released by the FDA regarding young-blood, a notice on the companies site said it would no longer offer the ...
Transfusion-related acute lung injury
Pain management information for pain medicine healthcare professionals in treating and caring for their patients. Clinical Pain Advisor offers news, case studies and more.
The FDA Black Box Warning for ESAs - AAKP
On May 9, 2007, the U.S. Food and Drug Administratio issued a public health advisory outlining new safety information about ESAs  . This included a new black box warning advising physicians to adjust the ESA dose to maintain the lowest hemoglobin level needed to avoid the need for a blood transfusion. Physicians and patients were to weigh the risks of ESAs against the risks of a blood transfusion.. The American Association of Kidney Patients, in cooperation with its Medical Advisory Board quickly responded, noting that:. • The history of ESAs dates to 1989 [2, 3] . Since their introduction, the. hospitalization rate, blood transfusion rate and blood borne illness rate have. dropped. In addition, ESRD mortality rates and quality of life for all CKD. patients have improved  .. • Although originally designed and approved by the FDA as a measure to avoid. blood transfusions, the clinical practice patterns since 1989 have evolved such. that current standard of care, is to use ESAs to ...
Kidshealth: Blood Transfusions | Akron Childrens Hospital
In the United States, the blood supply for transfusions comes from people who volunteer to donate their blood. Donors give blood at local blood banks, at community centers during blood drives, or through the American Red Cross.. When people know they are going to have an operation that might include a blood transfusion, they may choose to receive blood from one of several different places. Most patients choose to receive blood from the donated supply, but some decide to use their own blood. Providing your own blood before surgery is called autologous (pronounced: aw-TAHL-uh-gus) blood donation.. Another option for blood transfusions is called directed donation. This is when a family member or friend donates blood specifically to be used by a designated patient. For directed donation, the donor must have a blood type that is compatible with the recipients. He or she must also meet all the requirements of a regular volunteer blood donor. There is no medical or scientific evidence that blood from ...
Islami Bank Medical College
Pediatrics • Surgery • Cardiology • Psychiatry • Physical Medicine • Blood Transfusion • Gastroenterology • Orthopedic • ...
Works from this time include Restraining Psychotic at Holding Station, Guam; Blood Transfusion; Dying Boy and Walking Wounded. ...
Giant platelet disorder
Blood Transfusion. 7 (4): 278-292. doi:10.2450/2009.0078-08. ISSN 1723-2007. PMC 2782805 . PMID 20011639. "Bernard-Soulier ... Platelet transfusion is the main treatment for people presenting with bleeding symptoms. There have been experiments with DDAVP ... Giant platelets cannot stick adequately to an injured blood vessel walls, resulting in abnormal bleeding when injured. Giant ... Abnormality of the abdomen, nosebleeds, heavy menstrual bleeding, purpura, too few platelets circulating in the blood, and ...
He received two transfusions, and died after the second. In the winter of 1667, Denys administered transfusions of calf's blood ... It wasn't until after Karl Landsteiner's discovery of the four blood groups in 1902 that blood transfusions became safe and ... "The First Blood Transfusion?". Heart-valve-surgery.com. 2009-01-03. Retrieved 2010-02-09. "Red Gold . Innovators & Pioneers . ... Denys administered the first fully documented human blood transfusion on June 15, 1667. He transfused about twelve ounces of ...
Other blood thinners sometimes used in this setting include bivalirudin and fondaparinux. Platelet transfusions are not ... It is also important to ensure that the other blood cell types, such as red blood cells and white blood cells, are not also ... Smit-Sibinga, C. Th (2010-05-10). Neonatology and Blood Transfusion. Springer Science & Business Media. ISBN 9780387236001. ... Thrombocytopenia usually has no symptoms and is picked up on a routine full blood count (or complete blood count). Some ...
"Tranexamic acid". Clinical Transfusion. International Society of Blood Transfusion (ISBT). "Lysteda (tranexamic acid) Package ... In surgical corrections of craniosynostosis in children it reduces the need for blood transfusions. In spinal surgery (e.g., ... a short period of time before and after the surgery to prevent major blood loss and decrease the need for blood transfusions. ... Journal of Blood Transfusion. 2015: 874920. doi:10.1155/2015/874920. PMC 4576020 . PMID 26448897. Melvin JS, Stryker LS, Sierra ...
Effect of blood transfusions on subsequent kidney transplants. Transplant Proc 1973; 4: 253-259. Terasaki PI, Cho YW, Cecka JM ... 1982). Blood transfusion and transplantation. New York: Grune & Stratton. ISBN 0-8089-1522-3. Retrieved 2008-12-13. Stuart ...
The symbol of the Irish Blood Transfusion Service is a pelican, and for most of its existence the headquarters of the service ... "Irish Blood Transfusion Service". IBTS. Retrieved 13 June 2012. Rothwell, David (2006). Dictionary of Pub Names. London, United ... An older version of the myth is that the pelican used to kill its young then resurrect them with its blood, again analogous to ... The legends of self-wounding and the provision of blood may have arisen because of the impression a pelican sometimes gives ...
Mujibur Rahman (scientist)
... in hematology and blood transfusion from South and Southeast Asia. After returning from Glasgow, Rahman served as the blood ... He set up 30 blood transfusion centres during his time in public service. He became an honorary member of the World Health ... He set up the Blood Transfusion Society in Bangladesh and acted as its president. Rahman wrote six books. He published research ... He established the first blood transfusion center at the Institute of Post Graduate Medicine and Research (now Bangabandhu ...
OSF St. Joseph Medical Center
... the 1929 first blood transfusion; first successful radiation therapy in the 1940s; the 1990 first open heart surgery; and first ...
free with registration) Harmening, Denise M. (2005). Modern Blood Banking & Transfusion Practices. F. A. Davis Company. ISBN 0- ... In blood banking, PEG is used as a potentiator to enhance detection of antigens and antibodies. When working with phenol in a ... polyethylene glycol allows a slowed clearance of the carried protein from the blood. The possibility that PEG could be used to ...
2008). "The Chikungunya epidemic in Italy and its repercussion on the blood system". Blood Transfusion = Trasfusione Del Sangue ... RT-PCR can also be used to quantify the viral load in the blood. Using RT-PCR, diagnostic results can be available in one to ... Fever occurs with the onset of viremia, and the level of virus in the blood correlates with the intensity of symptoms in the ... Because high amounts of virus are present in the blood in the beginning of acute infection, the virus can be spread from a ...
Health Sciences Authority
As a WHO Collaborating Centre, the agency is an appointed Regional Quality Management Training Centre for Blood Transfusion ... The Blood Services Group is the national blood service of Singapore and is responsible for the adequacy and safety of the ... The framework covers the recruitment of voluntary non-remunerated blood donors, stringent blood donation screening criteria, a ... and Singapore Blood Transfusion Service. Today, the agency's professional knowledge, skills and competencies are housed in ...
Treatment methods included vitamin K and FFP, as well as ventilator support and packed red blood cell transfusion (PRBC). At ... Complete blood count and blood smear was determined as normal. No abnormality in fibrinogen, liver function test, and bleeding ... Journal of Blood Disorders & Transfusion. Huang, Li-Wen (2017). "Bruised Black and Blue: Acquired Hypoprothrombinemia". The ... Prothrombin Blood Test: Determines if patient has deficient or low levels of Factor II. Vitamin K1 Test: Performed to evaluate ...
He was Director of the Medical Research Council's Blood Transfusion Research Unit (later the Experimental Haematology Unit), ... Blood transfusion in clinical medicine. Blackwell Scientific Publications. "Munks Roll Details for Patrick Loudon Mollison". ... Mollison, P; Loutit, J (1943). "Disodium-citrate-glucose mixture as a blood preservative". British Medical Journal (2): 744-745 ... the father of transfusion medicine'. Mollison was born on 17 March 1914, to Beatrice Marjorie, née Walker, and William Mayhew ...
West Nile fever
... or conjunctive exposure to infected blood. The US outbreak identified additional transmission methods through blood transfusion ... Scottish National Blood Transfusion Service. "West Nile virus". Mayo Clinic. Archived from the original on 26 October 2017. ... Rarely the virus is spread through blood transfusions, organ transplants, or from mother to baby during pregnancy, delivery, or ... Centers for Disease Control and Prevention (CDC) (2002). "Investigation of blood transfusion recipients with West Nile virus ...
"Improving the safety of whole blood-derived transfusion products with a riboflavin-based pathogen reduction technology". Blood ... As of 2017 a system is marketed by Terumo in Europe that is used to remove pathogens from blood; donated blood is treated with ... Lane M, Alfrey CP (Apr 1965). "THE ANEMIA OF HUMAN RIBOFLAVIN DEFICIENCY". Blood. 25: 432-442. PMID 14284333. Smedts HP, ... which causes anemia with large blood cells (megaloblastic anemia). Deficiency of riboflavin during pregnancy can result in ...
Nil Ratan Sircar Medical College and Hospital
Transfusion Medicine & Blood Bank 8. Chest Medicine (Pulmonology) 9. Oncology and Radiotherapy "Department of Health and Family ...
MNS antigen system
"Table of blood group antigens within systems". International Society for Blood Transfusion. Archived from the original on 2011- ... Blood Group Antibodies and Their Significance in Transfusion Medicine. Transfus Med Rev 2007; 21: 58-71. Daniels G. Human Blood ... International Society of Blood Transfusion Committee on Terminology for Red Cell Surface Antigens: Cape Town Report. Vox Sang ... Anti-S, anti-s and anti-U antibodies are acquired following exposure (via pregnancy or past transfusion with blood products) ...
Harmening, Denise M. (2005). Modern Blood Banking & Transfusion Practices. F. A. Davis Company. ISBN 0-8036-1248-6. ... Albumin acts as a potentiator by reducing the zeta potential around the suspended red blood cells, thus dispersing the ... Potentiators are used in the clinical laboratory for performing blood banking procedures that require enhancement of ... but also by increasing the amount of antibody taken up by the red blood cell during sensitization. LISS is a solution of ...
Royal Infirmary of Edinburgh
Scottish National Blood Transfusion Service. Retrieved 28 November 2014. Henley W E (1875): Hospital Outlines: Sketches and ... "Transplant Units". NHS Blood and Transplant. Retrieved 24 February 2014. "TAVI Accredited Centres" (PDF). Edwards Lifesciences ...
It can also be sexually transmitted and potentially spread by blood transfusions. Infections in pregnant women can spread to ... Like other flaviviruses it could potentially be transmitted by blood transfusion and several affected countries have developed ... Diagnosis is by testing the blood, urine, or saliva for the presence of the virus's RNA when the person is sick, or the blood ... The U.S. FDA has recommended universal screening of blood products for Zika. The virus is detected in 3% of asymptomatic blood ...
History of surgery
Blood transfusion was pioneered. 1916. Austrian surgeon Hermann Schloffer performed the first splenectomy operation. 1917. Kiwi ... Austrian physician Karl Landsteiner discovered the basic A-B-AB-O blood types. 1903. Dutch physician Willem Einthoven invented ... He also described more efficient techniques for the effective ligation of the blood vessels during an amputation. Another ... Erasistratus, however, theorized that many diseases were caused by plethoras, or overabundances, in the blood, and advised that ...
An example is blood transfusion; in recent years, to reduce the risk of transmissible infection in the blood supply, donors ... blood transfusion reaction, air embolism, falls, mediastinitis, urinary tract infections from catheters, pressure ulcer, and ... The result has been a critical shortage of blood for other lifesaving purposes, with a broad impact on patient care. ... covering medication or transfusion reactions, communication or consent issues, wrong patient or procedures, communication ...
B.J. Medical College, Ahmedabad
Permitted for increase of seats from 18 to 28 u/s 10A.) Immuno-haematology & Blood Transfusion, 2. Recognized for 1 seat when ...
Blood transfusion may be life saving. Rare sequelae include Hypopituitarism Sheehan's syndrome. The maternal mortality rate ( ... blood pressure(rarely taken on newborns in the pre-hospital setting) oxygen saturation, blood sugar, and EKG monitoring. They ... Hemorrhage, or heavy blood loss, is still the leading cause of death of birthing mothers in the world today, especially in the ... Heavy blood loss leads to hypovolemic shock, insufficient perfusion of vital organs and death if not rapidly treated. ...
Smoking and pregnancy
The mother can lose blood and can have a haemorrhage; she may need a blood transfusion. placenta previa, where in the placenta ... When the placenta does not develop fully, the umbilical cord which transfers oxygen and nutrients from the mother's blood to ... The nicotine in cigarette smoke constricts the blood vessels in placenta and carbon monoxide, which is poisonous, enters the ... high blood pressure), and cardiovascular disease (any affliction related to the heart but most commonly the thickening of ...
This is termed "aplastic crisis" (also called reticulocytopenia). It is treated with blood transfusion. Parvovirus infection in ... by blood transfusions). There is some evidence that intrauterine Parvovirus B19 infection leads to developmental abnormalities ... It is classified as erythrovirus because of its capability to invade red blood cell precursors in the bone marrow. Three ... Although most patients have a decrease of erythropoiesis (production of red blood cells) during parvovirus infection, it is ...
Emergency Medical Retrieval Service
"Blood on board" (Press release). Scottish National Blood Transfusion Service (SNBTS). 27 March 2015. Retrieved 12 December 2015 ... Collaboration with the Scottish National Blood Transfusion Service (SNBTS) allows the EMRS to have O-negative blood immediately ... In June 2014 EMRS teams began to routinely carry a stock of O negative blood to allow transfusion earlier when responding to ...
Sergei Yudin (surgeon)
Transfusion of cadaver blood. JAMA 1936;106:997-9 1930 March 23: Russian surgeon Sergei Yudin performs first transfusion of ... Yudin also pioneered the transfusion of cadaveric blood and performed this successfully for the first time on March 23, 1930. ... Judine S. La transfusion du sang de cadavre a` l'homme. Paris: Masson et Cie; 1933. Judin S. Partial gastrectomy in acute ... In 1930, Yudin organized the world first blood bank at the Nikolay Sklifosovskiy Institute, which set an example for the ...
White N, Bayliss S, Moore D (January 2015). "Systematic review of interventions for minimizing perioperative blood transfusion ... becoming more popular due to the resultant rapid recovery of the child and reduced need for blood transfusion. The ... Impaired venous outflow is often caused by a hypoplastic jugular foramen. This causes an increase in the intracranial blood ... Most surgeons will not intervene until after the age of six months due to the heightened risk which blood loss poses before ...
A 2015 study of users in the United States also found elevated blood lead levels in 40 percent of those tested. Other concerns ...
ଜଣ୍ଡିସ୍ - ଉଇକିପିଡ଼ିଆ
ଅଧିକ ଅନକଞ୍ଜୁଗେଟେଡ ବିଲିରୁବିନ ହେବାର କାରଣ: ହେମୋଲାଇଟିକ ଆନିମିଆ (excess red blood cell breakdown), ବିରାଟ ଅଧଃକ୍ଷତ (large bruise), ... exchanged transfusion) କରାଯାଏ । ଗଲୁ ହେଉଥିଲେ ପିତ୍ତକୋଷରୁ ପିତ୍ତ ନିସ୍କାଷନ କରାଯାଏ ବା ଉର୍ସୋଡିଓଲ (ursodeoxycholic acid) ଔଷଧ ଦିଆଯାଏ ...
For example, some argue that the principles of autonomy and beneficence clash when patients refuse blood transfusions, ... After examination for signs and interviewing for symptoms, the doctor may order medical tests (e.g. blood tests), take a biopsy ... Subspecialties include transfusion medicine, cellular pathology, clinical chemistry, hematology, clinical microbiology and ... "Chairman's Reflections: Traditional Medicine Among Gulf Arabs, Part II: Blood-letting". Heart Views. 5 (2): 74-85 . 2004. ...
Since liquid blood and the vessels are not very dense, a contrast with high density (like the large iodine atoms) is used to ...
Fluid replacement, blood transfusion, and fighting hypotension are usually required. Intravenous interferon therapy has also ... Other laboratory findings in Lassa fever include lymphocytopenia (low white blood cell count), thrombocytopenia (low platelets ... and elevated aspartate transaminase levels in the blood. Lassa fever virus can also be found in cerebrospinal fluid. ... to avoid contact with blood and body fluids. These issues in many countries are monitored by a department of public health. In ...
Basic blood tests can be used to check the concentration of hemoglobin, platelets, sodium, potassium, chloride, bicarbonate, ... Blood products including intravenous immunoglobulin and a process known as plasma exchange can also be employed. ... An erythropoetin stimulating agent may be required to ensure adequate production of red blood cells, activated vitamin D ... Treatments in nephrology can include medications, blood products, surgical interventions (urology, vascular or surgical ...
Therapeutic concentrates are prepared from the blood plasma of blood donors. The US FDA has approved the use of four alpha-1 ... Transfusion. 46 (11): 1959-77. doi:10.1111/j.1537-2995.2006.01004.x. PMID 17076852. Campos, Michael A.; Alazemi, Saleh; Zhang, ... In blood test results, the IEF results are notated as in PiMM, where Pi stands for protease inhibitor and "MM" is the banding ... When the blood contains inadequate amounts of A1AT or functionally defective A1AT (such as in alpha-1 antitrypsin deficiency), ...
Operación Puerto doping case
... blood transfusions, growth hormone, a hormone taken by menopausal women and anabolic steroids. ... Fuentes would run the blood through a centrifuge, separating the blood plasma from the red blood cells. The cells would be re- ... The judge also ruled on a request to hand over blood bags to the Spanish Anti-Doping Agency. The judge ordered the blood bags ... Inside the Blood Doping Investigation, Der Spiegel, 10 July 2006 *^ a b Fuentes: "Me indigna la filtración selectiva", El País ...
Fluorescence in situ hybridization
FISH is a very general technique. The differences between the various FISH techniques are usually due to variations in the sequence and labeling of the probes; and how they are used in combination. Probes are divided into two generic categories: cellular and acellular. In fluorescent "in situ" hybridization refers to the cellular placement of the probe Probe size is important because longer probes hybridize less specifically than shorter probes, so that short strands of DNA or RNA (often 10-25 nucleotides) which are complementary to a given target sequence are often used to locate a target. The overlap defines the resolution of detectable features. For example, if the goal of an experiment is to detect the breakpoint of a translocation, then the overlap of the probes - the degree to which one DNA sequence is contained in the adjacent probes - defines the minimum window in which the breakpoint may be detected. The mixture of probe sequences determines the type of feature the probe can detect. ...
Therefore, the diagnosis of an immunodermatological disease is often delayed.Tests are performed on blood and tissues that are ...
Pope John XXIII
On 25 May 1963, the pope suffered another haemorrhage and required several blood transfusions, but the cancer had perforated ... 1990). The Keys of this Blood. New York: Simon & Schuster. ISBN 0-671-69174-0.. ... Across the centuries our brother Abel has lain in blood which we drew, or shed tears we caused by forgetting Thy love. Forgive ...
"American Idol's' Casey Abrams Had Two Blood Transfusions While Hospitalized". The Hollywood Reporter. March 10, 2011. Retrieved ... and that occasionally requires blood transfusions, which resulted in his having to be hospitalized while on American Idol. ...
Index of HIV/AIDS-related articles
wasting syndrome - Western blot - white blood cells - wild-type virus - window period - Women's Interagency HIV Study (WIHS) - ... transfusion - translation - transmission - transplacental - treatment IND - triglycerides - tuberculin skin test (TST) - ... blood-brain barrier - body fat redistribution (BFR) syndrome - body fluids - bone marrow - bone marrow suppression - booster - ... complete blood count (CBC) - computed tomography scan (C-T scan) - concomitant drugs - condyloma - condyloma acuminatum - ...
டெங்குக் காய்ச்சல் - தமிழ் விக்கிப்பீடியா
"Emerging infectious disease agents and their potential threat to transfusion safety". Transfusion 49 Suppl 2: 1S-29S. doi: ... "Threat of dengue to blood safety in dengue-endemic countries". Emerg. Infect. Dis. 15 (1): 8-11. doi:10.3201/eid1501.071097 ...
배아줄기세포 - 위키백과, 우리 모두의 백과사전
"Transfusion Medicine (Oxford, England)》 18 (1): 1-12. ISSN 1365-3148. PMID 18279188. doi:10.1111/j.1365-3148.2007.00807.x.. ... "Embryonic stem cells help deliver 'good genes' in a model of inherited blood disorder". 》ScienceDaily》. 2011년 2월 13일.. ...
... surgical techniques are used to remove an invasive malignancy that extends to the clitoris. Standard surgical procedures are followed in these cases. This includes evaluation and biopsy. Other factors that will affect the technique selected are age, other existing medical conditions, and obesity. Other considerations are the probability of extended hospital care and the development of infection at the surgical site. The surgery proceeds with the use of general anesthesia, and prior to the vulvectomy/clitoridectomy an inguinal lymphyadenectomy is first done. The extent of the surgical site extends one to two centimeters beyond the boundaries of malignancy. Superficial lymph nodes may also need to be removed. If the malignancy is present in muscular tissue in the region, it is also removed. In some cases, the surgeon is able to preserve the clitoris though the malignancy may be extensive. The cancerous tissue is removed and the incision is closed. Post operative care may ...
Hepatit - Vikipedi
infections transmitted through blood transfusion". Wiad Parazytol. 57 (2), s. 77-81. PMID 21682090.. KB1 bakım: Birden fazla ad ...
Human white blood cells use enzymes such as NADPH oxidase to generate superoxide and other reactive oxygen species to kill ... "Status of Superoxide Dismutase in Transfusion Dependent Thalassaemia". North American Journal of Medical Sciences. 7 (5): 194- ... Cu-Zn-SOD available commercially is normally purified from bovine red blood cells. The bovine Cu-Zn enzyme is a homodimer of ...
exposure to cat feces, organ transplantation, blood transfusion, contaminated soil, water, grass, unwashed vegetables, ... mosquito bite, contact with bodily fluids, blood, tissues, breathing around butchered animals or raw milk ...
... a red blood cell) and the neutrophil (a type of white blood cell). The maturing metarubricyte (a stage in RBC maturation) will ...
ஏபிஓ குருதி குழு முறைமை - தமிழ் விக்கிப்பீடியா
"Irish Blood Transfusion Service - Irish Blood Group Type Frequency Distribution". Irish Blood Transfusion Service. பார்த்த நாள் ... "Turkey Blood Group Site". Kangrubu.com. பார்த்த நாள் 2010-11-19. *↑ "Frequency of major blood groups in the UK". Blood.co.uk. ... RACIAL & ETHNIC DISTRIBUTION of ABO BLOOD TYPES, BLOODBOOK.COM *↑ Blood Transfusion Division, United States Army Medical ... Blood Types - What Are They?, Australian Red Cross[தொடர்பிழந்த இணைப்பு] *↑ "Austrian Red Cross - Blood Donor Information". Old. ...
List of atheists in science and technology
Crile is now formally recognized as the first surgeon to have succeeded in a direct blood transfusion. ...
The exact cause is unclear. Risk factors include congenital heart disease, birth asphyxia, exchange transfusion, and ... The gut mucosal cells do not get enough nourishment from arterial blood supply to stay healthy, especially in very premature ... Preterm birth, congenital heart disease, birth asphyxia, exchange transfusion, prolonged rupture of membranes. ... blood in the stool, or vomiting of bile. ... infants, where the blood supply is limited due to immature ...
Young blood transfusion. *Zero balancing. Conspiracy theories. *Anti-fluoridation/Water fluoridation movement ...
Rejection of blood transfusions. Main article: Jehovah's Witnesses and blood transfusions. Jehovah's Witnesses refuse blood ... Though Jehovah's Witnesses do not accept blood transfusions of whole blood, they may accept some blood plasma fractions at ... Jehovah's Witnesses accept non-blood alternatives and other medical procedures in lieu of blood transfusions, and their ... Criticism has also focused on their rejection of blood transfusions, particularly in life-threatening medical situations, and ...
It is a peptide that causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall. A class of drugs ... Hypotensive transfusion reaction. References. *^ Marcos-Contreras OA, Martinez de Lizarrondo S, Bardou I, Orset C, ... further lowering blood pressure. Bradykinin dilates blood vessels via the release of prostacyclin, nitric oxide, and ... "Hyperfibrinolysis increases blood-brain barrier permeability by a plasmin- and bradykinin-dependent mechanism". Blood. 128 (20 ...
SIDA, a enciclopedia libre
"Risk of HIV-1 transmission for parenteral exposure and blood transfusion: a systematic review and meta-analysis". AIDS (Londres ... "Blood safety ... for too few". WHO. 2001. Arquivado dende o orixinal o 17 de xaneiro de 2005. Consultado o January 17, 2006.. ...
Further information: Blood product, Blood transfusion, and Blood substitute. A blood product (or blood-based product) is any ... People with sickle-cell disease may require frequent blood transfusions. Early blood transfusions consisted of whole blood, but ... component of blood which is collected from a donor for use in a blood transfusion. Blood transfusions can be life-saving in ... Blood transfusions may also be used to treat a severe anaemia or thrombocytopenia caused by a blood disease. People with ...
WHO | 10 facts on blood transfusion
An unnecessary transfusion exposes patients to the risk of infections such as HIV and hepatitis and adverse transfusion ... Unnecessary transfusions expose patients to needless risk. Often transfusions are prescribed when simple and safe alternative ... As a result such a transfusion may not be necessary. ...
... is a medical treatment to replace blood or portions of the blood lost through injury, ... Whole blood is now rarely given as a transfusion.. Blood for transfusions may come from anonymous donors, or a person can bank ... During a transfusion, people normally receive only the parts of blood needed to treat their conditions. ...
Blood transfusion and its benefits in palliative care
The place of blood transfusion in the alleviation of symptoms within palliative care units is less well established. There has ... The value of blood transfusion as a supportive treatment in haematological disease and oncology is well established and is seen ... Blood transfusion and its benefits in palliative care Palliat Med. 1995 Oct;9(4):307-13. doi: 10.1177/026921639500900405. ... The place of blood transfusion in the alleviation of symptoms within palliative care units is less well established. There has ...
... could not be adequately treated without blood and blood-product transfusions.. Blood transfusions can carry very harmful and ... The Church recognizes that the use of blood transfusions and blood products often saves lives by replacing blood serum volume, ... The Church, however, leaves the decision of whether to be a donor or a recipient of a blood transfusion or blood products to ... In fact, individual wards sometimes have blood drives to increase a supply on hand when a ward member might need a transfusion ...
Blood School: Building a Foundation for Transfusion Safety
... Page Content. Please note: AABB reserves the right to make updates ... an eight-hour introductory course on transfusion safety for nurses. Recognizing that primary blood transfusion education was ... Home , Professional Development , eLearning , Blood School: Building a Foundation for Transfusion Safety ... Review the benefits of a dedicated transfusion education program in enhancing clinical practice and transfusion safety. ...
Blood Transfusion May Explain Women's Greater Cardiac Surgery Mortality | Medpage Today
... womens increased likelihood of complications or death after cardiac surgery to an increased likelihood of receiving red blood ... Blood transfusions also correlated with more days of fever (P. P. Exactly why women are more likely to receive blood ... "Wider use of leukoreduced [red blood cell] transfusions and multimodal approaches to blood conservation and anemia prevention, ... The use of transfusions has increased by 64% from 1997 to 2003. Cardiac surgery accounts for about 20% of all allogeneic blood ...
Blood Transfusions During Pregnancy - American Pregnancy Association
This article covers the side effects of blood transfusions during pregnancy. ... Wondering if a blood transfusion during pregnancy is right for you? ... Blood Transfusions During Pregnancy: Final Notes. If youre asked to undergo a blood transfusion, make sure to get a full ... What are the Side Effects of a Blood Transfusion While Pregnant. You will be closely monitored during any blood transfusion ...
Seminars will tackle blood transfusion alternatives - tribunedigital-dailypress
A new nonprofit is bringing seminars on alternatives to blood transfusions to the Peninsula. The group, Hampton Roads Health ... Learn about alternatives to blood transfusion on June 24 and June 26. ... "A transfusion of a blood product carries risks. If we reduce the number of transfusions, we reduce the number of risks to a ... "Blood management is really being touted as the way we need to go, being conservative in our blood transfusions policies," said ...
Blueprint to reduce wasteful blood transfusions
... endorse recommendations for blood transfusions that reduce blood use to improve patient safety and outcomes. Publishing this ... Johns Hopkins Medicine) By analyzing data from randomized clinical trials comparing blood transfusion approaches, Johns Hopkins ... endorse recommendations for blood transfusions that reduce blood use to improve patient safety and outcomes. Publishing this ... Modelling mosquito-borne and sexual transmission of Zika virus in Australia: Risks to blood transfusion safety ...
A Risky Proposition: Blood Transfusion and the Risk of Surg... : Anesthesia & Analgesia
Red Blood Cell Transfusion and Surgical Site Infection After Colon Resection... * Opioid-Free Analgesia in the Era of Enhanced ... Home , October 2017 - Volume 125 - Issue 4 , A Risky Proposition: Blood Transfusion and the Risk of Surg... ... A Risky Proposition: Blood Transfusion and the Risk of Surgical Site Infections. Nathan, Naveen MD ... 1. Mazzeffi M, Tanaka K, Galvagno S. Red blood cell transfusion and surgical site infection after colon resection surgery: a ...
Had severe blood transfusion reaction, wonder which type? -Doctors Lounge(TM)
I have anemia and needed a blood transfusion and attempted my first transfusion last week. After about a tablespoon of blood ... Can a severe blood transfusion reaction be called a vasovagal reaction? They said there was no hemolyzation of the blood. What ... Question: Had severe blood transfusion reaction, wonder which type?. sunshine_sammi - Mon Sep 07, 2009 6:37 pm. Share , ... They had stopped the blood when I came to and said my blood pressure had dropped to 70/40 and my pulse had dropped. My family ...
Reducing Blood Transfusion Risk and Costs with Advanced CDS | Allscripts
Learn more about Reducing Blood Transfusion Risk and Costs with Advanced CDS ... A recent study in the journal Transfusions pegged the cost at between $522 and $1,183 per unit of blood. And despite the ... Like chemotherapy, blood transfusions can improve outcomes but only when used in the right patient for the right indication and ... Reducing Blood Transfusion Risk and Costs with Advanced CDS. By Steven H. Shaha, Ph.D., DBA 03/20/2012 ...
What Is a Blood Transfusion? Risks, Procedure, Side Effects
Blood transfusion reactions, side effects, risks, and complications include allergic reactions, infections, and lung injuries. ... The type of blood transfusion depends on the situation. ... routine procedure used for blood loss from severe injuries or ... To keep blood safe, blood banks carefully screen donated blood.. The risk of catching a virus from a blood transfusion is very ... The type of blood transfusion you need depends on your situation.. Red Blood Cell Transfusions. Red blood cells are the most ...
Blood transfusion - Wikipedia
Blood donation. Main article: Blood donation. Blood transfusions use as sources of blood either ones own (autologous ... Blood transfusion is the process of transferring blood or blood products into ones circulation intravenously. Transfusions ... Red cell transfusion. Main article: Packed red blood cells. Historically, red blood cell transfusion was considered when ... Transfusion Evidence Library searchable source of evidence for transfusion medicine.. Blood Transfusion Societies. * ...
Blood transfusion - NHS
A blood transfusion is when youre given blood from someone else (a donor). Its a very safe procedure that can be life-saving. ... Blood transfusion A blood transfusion is when youre given blood from someone else (a donor). Its a very safe procedure that ... A blood transfusion can replace blood youve lost, or just replace the liquid or cells found in blood (such as red blood cells ... These can reduce your chances of needing a blood transfusion.. Giving blood afterwards. Currently, you cant give blood if ...
Re: blood transfusion
... Caroline Kaufmann. * *RE: blood transfusion Heikkinen, Megan B. * *RE: blood transfusion Caroline ... RE: blood transfusion Caroline Kaufmann. * *Re: blood transfusion Belinda. * * ... Re: blood transfusion Lance Mon, 15 Oct 2007 09:40:35 -0700 ... blood transfusion Angela B.. * *Re: blood transfusion Lance. * ...
Cadaveric blood transfusion - Wikipedia
Cadaveric blood transfusion is the transfusion of blood from a dead body to a living person. In 1929, professor Vladimir Shamov ... Blood transfusion from cadaver, Trudi Ukrain. Suezda. Khir. 1929;18:184. Shamov WN. The transfusion of stored cadaver blood ... Transfusion of cadaver blood. JAMA 1936;106:997-9. Swan H, Schechter D. The transfusion of blood from cadavers. A historical ... Transfusion of Human Corps Blood without Additives.Transfusion. 1964;4:112-7. www.anes.uab.edu. ...
Autologous blood transfusion | The BMJ
Blood Transfusion | Blood Donation | MedlinePlus
Get information on blood donation, the blood donation process, and blood transfusion. ... To keep blood safe, blood banks carefully screen donated blood. The risk of catching a virus from a blood transfusion is low. ... Sometimes it is possible to have a transfusion of your own blood. During surgery, you may need a blood transfusion because of ... Blood donation before surgery (Medical Encyclopedia) Also in Spanish * Blood transfusions (Medical Encyclopedia) Also in ...
Blood transfusion medicine | The BMJ
In the past few years there has been increasing concern about blood transfusion safety. Avoidable transfusion errors, mostly in ... Risks of red blood cell transfusion (adapted from British Committee for Standards in Haematology (2001)1) ... Finally it emphasises the need for careful education and training of all those involved in blood prescribing and blood ... Concerted efforts must now be made to reduce inappropriate blood use and to use alternatives and blood sparing agents ...
Blood transfusion | NICE
Blood transfusion. Number. NG24. Date issued. November 2015. Other details. Is this a recommendation for the use of a ... Red blood cell transfusion thresholds for patients with chronic cardiovascular disease:- What is the clinical and cost ... Why this is important:- The literature suggests that there may be some evidence of harm with the use of restrictive red blood ... but further studies are needed to determine the optimal transfusion threshold for patients with chronic cardiovascular disease. ...
Blood transfusion | NICE
Blood transfusion. Number. NG24. Date issued. November 2015. Other details. Is this a recommendation for the use of a ... Fresh frozen plasma transfusions may cause adverse outcomes in people who are critically ill, including transfusion-related ... This study showed that a high proportion of fresh frozen plasma transfusions had unproven clinical benefit.. Better evidence ... acute lung injury, transfusion-related circulatory overload, multi-organ failure and an increased risk of infections.. A ...
Zika and Blood Transfusion | Zika virus | CDC
... territories screen donated whole blood and blood components with a blood screening nucleic acid test licensed for use by FDA. ... Zika Virus Blood Screening. *Blood donor screening on the basis of a questionnaire, without a laboratory test, is insufficient ... For Blood Collection Centers and Health Departments. One of the most important aspects of blood safety is making sure donated ... Blood donations that test positive for Zika virus are removed from the blood supply. ...
A blood transfusion is a safe and relatively simple medical procedure that replaces blood lost during surgery or because of an ... Why Blood Transfusions Are Performed. The three main reasons why a child may need a blood transfusion are:. *Loss of blood ... A blood transfusion can make up for a loss of blood or any part of the blood. Although whole blood can be transfused, it is ... These markers determine if someone has type A blood, type B blood, type O blood, or type AB blood. Each blood type also can be ...
N] Blood Transfusion / [L] Pogorevka : RedditRescueForce
Blood transfusion - Drugs.com
It also can help if an illness prevents your body from making blood correctly. ... A blood transfusion can help replace blood lost due to surgery or injury. ... Your blood will be tested before a transfusion to determine whether your blood type is A, B, AB or O and whether your blood is ... A blood transfusion also can help if an illness prevents your body from making blood or some of your bloods components ...
WHO with support from Government of Japan strengthens blood transfusion services for safe, sustainable and quality blood in...
Blood transfusion is one of the therapeutic procedures performed during hospitalizations and undoubtedly helps patients who are ... injured, having surgery, receiving treatments or are being treated for diseases that affect the blood. ... Technical Officer for Blood Transfusion Safety.. "Blood transfusion safety is a critical intervention in the national health ... Juba, 1 December 2017: Every second, someone in the world needs blood. Blood transfusion is one of the therapeutic procedures ...
Blood Transfusion and Donation - Multiple Languages: MedlinePlus
Health Information on Blood Transfusion and Donation: MedlinePlus Multiple Languages Collection ... Blood Transfusion and Donation: MedlinePlus Health Topic - English Transfusión y donación de sangre: Tema de salud de ... Receiving Blood Transfusions - 简体中文 (Chinese, Simplified (Mandarin dialect)) Bilingual PDF ... Receiving Blood Transfusions - 繁體中文 (Chinese, Traditional (Cantonese dialect)) Bilingual PDF ...
Blood transfusion - Canadian Cancer Society
Some people may need a blood transfusion to treat anemia. Learn about getting a blood transfusion. ... Blood transfusion. A blood transfusion is a way to give blood to someone who needs it. Some people may need blood if they have ... Before a blood transfusion. If you need a blood transfusion, you will have a blood test to find out your blood type and Rh ... A blood transfusion may give whole blood, which includes all of the components of blood. A transfusion may also give only part ...
Description of blood transfusion alternatives?
... blood transfusion, blood disorders, blood - Answer: Normally the answer to that is death. I wouldnt be here if some ... ... Home › Q & A › Questions › Description of blood.... Description of blood transfusion alternatives?. Asked. 12 Jan 2016 by ... clearly if you are losing red blood that would normally need a blood transfusion or platelets and will only accept the ... Aleve - I have been in the hospital with Chrons desease and have many blood transfusions due to?. Posted 25 May 2010 • 1 answer ...
Coagulation and Blood Transfusion | SpringerLink
Today marks the third lustrum of the annual international sympo- sium on blood transfus ... Coagulation and Blood Transfusion. Proceedings of the Fifteenth Annual Symposium on Blood Transfusion, Groningen 1990, ... Today marks the third lustrum of the annual international sympo- sium on blood transfusion, organized by the Rode Kruis ... The Use of Aprotinin in Cardiopulmonary Bypass and the Impact on Hemostasis and Blood Transfusion ...
Blood Transfusion and Organ Donation | West Nile Virus | CDC
You cannot get West Nile virus by donating blood.. Can I get infected with West Nile virus by receiving a blood transfusion?. ... Is donated blood tested for West Nile virus?. Yes. All donated blood is tested for West Nile virus. Any blood product found to ... A small number of West Nile virus infections acquired from blood transfusions have been reported. However, blood collection ... Can I get infected with West Nile virus by donating blood?. *Can I get infected with West Nile virus by receiving a blood ...
Hong Kong woman dies after blood-transfusion beauty treatment
Jehovah's Witnesses and blood transfusions - Wikipedia
Blood introduced directly into the veins circulates and functions as blood, not as nutrition. Hence, blood transfusion is a ... In 1945, the application of the doctrine on blood was expanded to prohibit blood transfusions of whole blood, whether ... ingesting blood and that Christians should not accept blood transfusions or donate or store their own blood for transfusion. ... This includes the use of red blood cells, white blood cells, platelets and blood plasma. Other fractions derived from blood are ...
Indian Journal of Hematology and Blood Transfusion | Home
Indian Journal of Hematology and Blood Transfusion is a medium for propagating and exchanging ideas within the medical ... Co-publication with the Indian Society of Hematology and Blood Transfusion Visit Co-Publisher Site: Indian Society of ... Indian Journal of Hematology and Blood Transfusion is a medium for propagating and exchanging ideas within the medical ... The Journal is the official publication of The Indian Society of Hematology & Blood Transfusion. ...
The New Era of Blood-transfusion - Scientific American
It would thus seem that the victory registered over the material is as blood-stirring as the surgical triumph of transfusion ... Denys, through animal-experimentation, arrived at conclusions as to choice of blood-vessels in transfusion which are held valid ... It was learned that that microscopic body, the white corpuscle, was back of the blood-clot; that when the ends of blood-vessels ... This article was originally published with the title "The New Era of Blood-transfusion" ...
Blood Transfusions for Beta Thalassemia
Learn when you might need a transfusion and what to expect. ... Blood transfusions are part of the treatment routine for some ... people with a blood disorder called beta thalassemia. ... Blood Transfusions for Beta Thalassemia. Blood transfusions ... National Heart, Lung, and Blood Institute: "Blood Transfusion.". USCF Benioff Childrens Hospital: "Blood Transfusions," " ... The disease causes a drop in the amount of red blood cells you have. A transfusion gives you healthy red blood cells from a ...
Blood transfusion - Islamweb - Fatwas
Donating blood Date: 12-8-2000. Does Islam allow a person to give blood? For example, donating blood at a blood drive... More ... Reward for donating blood Date: 22-4-2004. Since donating blood can save 6 lives per blood donation, if you donate blood with ... The blood is usually processed and the blood plasma (where blood cells are suspended) is separated from the blood by ... Blood donation to a person does not render him/her a Mahram Date: 15-11-2005. Is donating blood allowed in Islam? If blood ...
Malaria and blood transfusion
Is it possible to contract malaria from blood transfusions and if so does , , blood have to be screened for the protozoan in ... Amber, , , Since I grew up in Eritrea, East Africa and have had Malaria, I knew , the blood folks would not take my blood until ... Malaria and blood transfusion. John Kobayashi johnk at u.washington.edu Sat Nov 21 18:04:35 EST 1998 *Previous message: Malaria ... While transfusion associated malaria is quite possible, but it is rarely reported in the us. Blood banks check potential donors ...
Blood Transfusion | HealthLink BC
Whole blood is now rarely given as a transfusion.. Blood for transfusions may come from anonymous donors, or a person can bank ... Blood transfusion is a medical treatment to replace blood or portions of the blood lost through injury, surgery, or disease. ... During a transfusion, people normally receive only the parts of blood needed to treat their conditions. ...
Receiving red blood cell transAcute lung iPlateletsRisksCellDonorRandomized clinicAnemiaInfectionMortalityOutcomesHospitalizationSeverePatient'sHemoglobinMethodsPracticeSurgicalDonorsProcedureIncidence of blood transfusionRiskSignificantlyPatientCardiacPalliative careIndication for transfusionPracticesAdverseSurgery
Receiving red blood cell trans1
- Patients in the ICU who are receiving red blood cell transfusion as part of their normal clinical management will be given, randomly, either the freshest available blood or the standard aged blood in their hospital -as is current practice. (hrb.ie)
Acute lung i3
- According to The Strategic Healthcare Group , the leading causes of transfusion-related morbidity and mortality are unrelated to viral transmission and include bacterial contamination of platelets (1:2000- 3000 transfusions), transfusion errors from patient misidentification (1:16,000- 19,000), transfusion related acute lung injury (TRALI) (1:1000- 5000) and transfusion associated circulatory overload (TACO) (1:350). (allscripts.com)
- Two complications in particular, transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO), are especially concerning. (elsevier.com)
- In-hospital complications were defined as adult respiratory distress syndrome, sepsis, disseminated intravascular coagulation, renal insufficiency, and transfusion-related acute lung injury. (elsevier.com)
- ANN ARBOR, Mich., Dec. 3 -- Researchers have linked women's increased likelihood of complications or death after cardiac surgery to an increased likelihood of receiving red blood cells or platelets during the procedure. (medpagetoday.com)
- Women also tended to receive greater quantities of blood then male patients, receiving 9.2 units of unfiltered blood compared with 6.3 units ( P =0.024), 16 units of whole blood-derived donor platelets compared with 6.7 ( P =0.021), and 4.9 units of prestorage leukoreduced red blood cells compared with 3.0 ( P =0.001). (medpagetoday.com)
- The study did have several limitations, the researchers noted, including the fact that they did not assess the independent effects of platelets because they were co-administered with red blood cells. (medpagetoday.com)
- Platelets are fragments of blood cells that help with clotting. (ucsd.edu)
- Although platelets should be "typed" to match your blood type, it is not needed. (ucsd.edu)
- Few outside the inner circle of blood banks and surgeons know that the costs and risks associated with everyday blood transfusions are significant. (allscripts.com)
- And despite the routine nature of transfusions, the procedure carries sobering and serious clinical risks. (allscripts.com)
- My grandmother was not told that there are risks associated with allogeneic transfusion nor was any alternative therapy offered. (mediware.com)
- Transfusion informed consent is a necessary element of the physician-patient relationship because transfusion is an invasive procedure (a tissue transplant) with definable significant risks. (mediware.com)
- If the physician does not weigh the risks of transfusion against the benefits when ordering blood products, then that physician will not likely discuss risks and benefits with the patient. (mediware.com)
- The physician should order transfusion education for the patient and explain in plain words why a transfusion may be needed, the expected benefits, the common risks and the alternatives available to avoid or reduce transfusion. (mediware.com)
- While referring to a document written at the 5th grade comprehension level, 11 the physician explains why the patient may need a transfusion, outlines the steps he will take to prevent or minimize the patient's exposure to blood products and tells the patient about the common risks of transfusion. (mediware.com)
- You will also need to sign a consent form that says that you understand the potential risks of receiving a transfusion. (ucsd.edu)
- Due to the severe risks involved, these transfusions are rarely used. (ucsd.edu)
- BACKGROUND: Blood transfusions may influence the recipients' cancer risks both through transmission of biologic agents and by modulation of the immune system. (sdu.dk)
- The link between infection and allogeneic transfusions is still a subject of debate in the medical community, but donor blood may increase humoral immunity and decrease cell-mediated immunity, the researchers said. (medpagetoday.com)
- Wider use of leukoreduced [red blood cell] transfusions and multimodal approaches to blood conservation and anemia prevention, as in bloodless medicine and surgery programs, may provide particular benefit to women," the study authors conclude. (medpagetoday.com)
- A recent study of cats reported that administration of crossmatch compatible blood transfusions resulted in significantly greater increases in the post-transfusion red blood cell level when compared to administration of non-crossmatched blood (Weltman and others, 2014). (rvc.ac.uk)
- Red blood cell (RBC) transfusion is required to treat a number of life threatening conditions within the general hospital setting and Intensive Care Units (ICU). (hrb.ie)
- Red blood cell units represent a very limited but essential resource. (hrb.ie)
- This can lower your blood cell counts. (ucsd.edu)
- Hemolytic disease of the fetus and newborn due to maternal red blood cell alloimmunization can have serious consequences. (readbyqxmd.com)
- However, the standardized incidence ratios for cancers of the tongue, mouth, pharynx, esophagus, liver, and respiratory and urinary tracts and for squamous cell skin carcinoma remained elevated beyond 10 years after the transfusion. (sdu.dk)
- Abnormalities of an individuals hemoglobin value can indicate defects in red blood cell balance. (vdocuments.mx)
- Patients who received AT had significantly lower packed red blood cell (p = 0.01) and platelet requirements (p = 0.01). (elsevier.com)
- Objective: To evaluate semen parameters and measure serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (T) concentrations before and 7 days after packed red cell transfusion (PCTx) in adults with sickle cell disease (SCD). (qscience.com)
- Basal serum concentrations of FSH, LH, T and IGF-I were evaluated before and 7 days after packed red cell transfusion (PCTx). (qscience.com)
- Explain to interested patients that women undergoing heart surgery may be more likely to experience complications largely due to the fact that they are more likely to receive transfusions of donor blood. (medpagetoday.com)
- In the cohort study of 380 patients who underwent primary coronary artery bypass graft surgery, primary valve replacement, or both during 1997 and 1998, 149 (99.3%) of 150 women in the study received donor blood during their hospitalization, compared with 77% of the men. (medpagetoday.com)
- This is how we check that donor blood and patient blood are compatible. (rvc.ac.uk)
- If no reaction is seen in this test, the donor is considered suitable and this should decrease the risk of the recipient having a reaction to the blood. (rvc.ac.uk)
- It would increase transfusion costs, lead to considerable delays in administering transfusions and decrease blood donor options. (rvc.ac.uk)
- Traditionally the sex of a blood donor has been considered irrelevant when giving a blood transfusion, but a compelling study is raising new concerns suggesting blood transfusions delivered to men using blood from previously pregnant women could increase their risk of dying in the years following the transfusion. (newatlas.com)
- Men who received a blood transfusion from a female donor who had previously been pregnant were one and half times more likely to die than if they had received a transfusion from a man, or a woman who had never been pregnant. (newatlas.com)
- It seems if a man is over the age of 50 he is immune to whatever specific risk factor is present in the blood of a formerly pregnant female donor. (newatlas.com)
- Gustaf Edgren, who has co-written an editorial on this new research, recently published a large scale investigation into whether or not the sex and age of a blood donor has any impact on the survival rate of a patient receiving their blood. (newatlas.com)
- Edgren concluded that the age or sex of a donor has no relevance in the mortality outcome of a blood transfusion. (newatlas.com)
- Johns Hopkins Medicine) By analyzing data from randomized clinical trials comparing blood transfusion approaches, Johns Hopkins experts, along with colleagues at Cleveland Clinic and NYU Langone Medical Center, endorse recommendations for blood transfusions that reduce blood use to improve patient safety and outcomes. (medworm.com)
- Patients who received allogeneic blood were 4.4 times more likely to develop an infection following cardiac surgery than those who didn't, and women were 44.6 times more likely to be transfused than men, reported Mary A.M. Rogers, Ph.D., M.S., of the University of Michigan in Ann Arbor, and colleagues in the December issue of the Journal of Women's Health . (medpagetoday.com)
- Patients who received allogeneic blood were 4.4 times more likely to develop an infection than those patients who did not undergo transfusion (95% CI: 1.5 to 13.2, P =0.009) with adjustment for demographic and clinical factors. (medpagetoday.com)
- To reduce complications related to blood transfusions, the study authors called for increased use of leukoreduction to diminish the chances of an inflammatory response or infection. (medpagetoday.com)
- In addition, this was not a randomized controlled trial so researchers could not tease out whether the relationship between transfusion and infection was due to underlying reasons for the transfusion and not the transfusion itself. (medpagetoday.com)
- We compared the incidence of blood transfusion, mortality rates, total hospitalization costs and hospital length of stay (LOS) among selected open and laparoscopic procedures. (sages.org)
- Mortality rates were significantly higher among those with blood transfusion compared to those without, for both open and laparoscopic procedures. (sages.org)
- Patients with blood transfusion had higher mortality rates, increased hospital length of stay and subsequent hospital costs. (sages.org)
- Severe anaemia in children is a leading cause of hospital admission and a major cause of mortality in sub-Saharan Africa, yet there are limited published data on blood transfusion in this vulnerable group. (biomedcentral.com)
- The quality and capacity of blood transfusion services could therefore have a major, direct effect on inpatient child mortality. (ox.ac.uk)
- Henrik Bjursten, another scientist working in the field, published a study on nearly 10,000 patients in 2016 and concluded that sex mismatched blood transfusions did in fact increase mortality risk. (newatlas.com)
- The latest study is the first to examine the relevancy of a female blood donor's pregnancy history and it asks the fundamental question of what could potentially be causing this strange increased risk of mortality? (newatlas.com)
- The authors of the study speculate a certain antibody formation that occurs during pregnancy could be what is triggering the increased mortality for men receiving transfused blood. (newatlas.com)
- Like chemotherapy, blood transfusions can improve outcomes but only when used in the right patient for the right indication and in the right dose. (allscripts.com)
- Table 1 describes the clinical and economic outcomes of laparoscopic and open procedures, with and without blood transfusion. (sages.org)
- The aim of this study was to assess outcomes in trauma patients receiving whole blood autotransfusion (AT) from hemothorax. (elsevier.com)
- Explain to interested patients that blood transfusion is the most common procedure performed during hospitalization and up to 71% of Americans will receive a transfusion at some point in their lives. (medpagetoday.com)
- Objective: The objective of this study was to examine the incidence of blood transfusion in selected open and laparoscopic abdominal surgical procedures and evaluate the impact of transfusion on hospitalization costs and length of hospital stay. (sages.org)
- Some time ago my delightful 80+ year-old grandmother was diagnosed with a GI bleed that led to hospitalization and multiple transfusions. (mediware.com)
- Had severe blood transfusion reaction, wonder which type? (doctorslounge.com)
- They said I had no fever but had a severe transfusion reaction. (doctorslounge.com)
- Can a severe blood transfusion reaction be called a vasovagal reaction? (doctorslounge.com)
- Except in severe blood loss, people with cancer receive "packed" red blood cells without plasma. (ucsd.edu)
- Blood transfusion for severe anaemia in children in a Kenyan hospital. (ox.ac.uk)
- 1 Further, AABB and College of American Pathologists (CAP) state that the patient's medical record shall include documentation of transfusion consent. (mediware.com)
- The transfusion consent process should begin at the time the physician determines that a patient's course of treatment may include transfusion. (mediware.com)
- Blood loss that occurs suddenly due to trauma may require an emergency transfusion to save a patient's life. (daltonanimalcare.com)
- AT was defined as transfusion of autologous blood from patient's hemothorax, which was collected from the chest tubes and anticoagulated with citrate phosphorous dextrose. (elsevier.com)
- CONCLUSION: The autologous transfusion of the patient's shed blood collected through chest tubes for hemothorax was found to be safe without complications in this study. (elsevier.com)
- Exactly why women are more likely to receive blood transfusions is not fully understood, but, the researchers said, women typically have lower normal hemoglobin and hematocrit levels. (medpagetoday.com)
- I quickly determined that she had no idea what hemoglobin was but she was confident her transfusion therapy was necessary because her trusted family physician had told her that her "hemoglobins were low. (mediware.com)
- Hemoglobin is the most important component of red blood cells. (vdocuments.mx)
- Methods: The Premier Perspective TM Database (PPD) was used to identify open and laparoscopic appendectomy, cholecystectomy, colectomy and Roux-en-Y gastric bypass surgical procedures in 2009. (sages.org)
- METHODS: We used computerized files from Scandinavian blood banks to identify a cohort of 888,843 cancer-free recipients transfused after 1968. (sdu.dk)
- METHODS: This is a multi-institutional retrospective study of all trauma patients who received autologous whole blood transfusion from hemothorax from two Level I trauma centers. (elsevier.com)
- Methods: This prospective study investigated 18 young adults with transfusion-dependent SCD, aged 20.7 +/- 2.88 years, with full pubertal development (Tanner's stage 5) (euogonadal), and capacity to ejaculate. (qscience.com)
- The Good Practice Guidelines (GPGs) chapter fully reflects the most recent changes in good manufacturing practices relevant for blood establishments. (edqm.eu)
- As veterinary practice has advanced, there has been a steady increase in the need for blood transfusions to help cats with a variety of diseases. (rvc.ac.uk)
- BACKGROUND: The practice of transfusing ones' own shed whole blood has obvious benefits such as reducing the need for allogeneic transfusions and decreasing the need for other fluids that are typically used for resuscitation in trauma. (elsevier.com)
- Cancer patients undergoing chemotherapy, surgical patients, pets with advanced kidney or liver disease, cats with feline leukemia, and pets with bleeding or clotting disorders are some examples of other patients that may require transfusion with blood or blood products. (daltonanimalcare.com)
- Our transfusion service allows us to provide blood and blood products for veterinary patients' medical, surgical, or emergency needs. (daltonanimalcare.com)
- Blood for transfusions may come from anonymous donors, or a person can bank his or her own blood in preparation for surgery. (rexhealth.com)
- However, identifying suitable blood donors and obtaining blood from healthy cats in a timely manner is extremely challenging. (rvc.ac.uk)
- If it can be shown that fresh blood improves survival in this very sick group, doctors will have a new treatment that may improve survival in our critically ill patients, However, in addition this study will ensure that Blood transfusion services can ensure their policies for recruitment of donors and allocation and storage of this product are based on the best available evidence. (hrb.ie)
- The study from a group of Dutch researchers looked at 31,118 patients who received blood transfusions and not only broke the data down by sex, but also by whether the female blood donors had ever been pregnant. (newatlas.com)
- 2 Meeting this ethical and regulatory obligation need not be complicated but a meaningful discussion between physician and patient comparable to that of any other invasive procedure seldom occurs prior to transfusion. (mediware.com)
- 4 This discussion may take place in the physician's office when a procedure or course of therapy is planned that includes a known risk for transfusion. (mediware.com)
Incidence of blood transfusion2
- The HSS transfusion initiative reduced risk to patients, as well as risk-associated exposure for ordering physicians and surgeons. (allscripts.com)
- In order to preserve this scarce resource and to reduce the risk of transfusion-transmitted infections, guidelines developed by the World Health Organization (WHO) encourage the rational use of blood transfusion [ 5 ]. (biomedcentral.com)
- CONCLUSIONS: The marked increase in cancer risk shortly after a blood transfusion may reflect the presence of undiagnosed occult cancers with symptoms that necessitated the blood transfusion. (sdu.dk)
- Conflicting data has been published in recent years over whether blood transfusions between sexes carry any risk. (newatlas.com)
- The group of patients entered into the study were anaemic in comparison with our normal patient population, but the degree of improvement seen did not correlate with the degree of anaemia prior to transfusion. (nih.gov)
- Publishing this week in JAMA Internal Medicine, the report also provides a how-to guide for launching a patient blood management program. (medworm.com)
- Therefore the actual age of blood that is used in each patient varies based on the rate of use and access to supply. (hrb.ie)
- I believe a major barrier to the physician-patient transfusion consent discussion is the physician's lack of knowledge about transfusion medicine. (mediware.com)
- Patient education that supports transfusion informed consent is essential for an effective consent process. (mediware.com)
- The Patient Education Institute offers a video that explains blood types and transfusion in simple terms. (mediware.com)
- Cardiac surgery accounts for about 20% of all allogeneic blood transfusions in the U.S, according to information cited in the new study. (medpagetoday.com)
- A 77-year-old man with a complex cardiac history presented to the emergency room with chief complaints of black tarry stools and low blood pressures for 4 days. (readbyqxmd.com)
- The place of blood transfusion in the alleviation of symptoms within palliative care units is less well established. (nih.gov)
Indication for transfusion1
- Those whose main indication for transfusion was weakness showed a particular benefit. (nih.gov)
- Fortunately, some leading provider organizations are leveraging technology to improve their transfusion practices. (allscripts.com)
- The technology initiative was accompanied by education for surgeons regarding up-to-date transfusion practices and models. (allscripts.com)
- "Standards" in the chapters aim to support safety and quality requirements for transfusion practices in Europe and beyond. (edqm.eu)
- We have previously developed a set of machine learning base models for predicting the likelihood of these adverse reactions, with a goal towards better informing the clinician prior to a transfusion decision. (elsevier.com)
- Blood transfusion is a medical treatment to replace blood or portions of the blood lost through injury, surgery, or disease. (rexhealth.com)
- Healthcare Informatics recently recognized The Hospital for Special Surgery (HSS) in New York City for a program that improved the safety and cost-efficiency of transfusions there. (allscripts.com)
- 001). Results showed significant reductions in blood per surgery. (allscripts.com)
- The surgery can cause blood loss the need for transfusions. (ucsd.edu)