Blood Transfusion: The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)Blood Transfusion, Autologous: Reinfusion of blood or blood products derived from the patient's own circulation. (Dorland, 27th ed)Erythrocyte Transfusion: The transfer of erythrocytes from a donor to a recipient or reinfusion to the donor.Platelet Transfusion: The transfer of blood platelets from a donor to a recipient or reinfusion to the donor.Exchange Transfusion, Whole Blood: Repetitive withdrawal of small amounts of blood and replacement with donor blood until a large proportion of the blood volume has been exchanged. Used in treatment of fetal erythroblastosis, hepatic coma, sickle cell anemia, disseminated intravascular coagulation, septicemia, burns, thrombotic thrombopenic purpura, and fulminant malaria.Blood Component Transfusion: The transfer of blood components such as erythrocytes, leukocytes, platelets, and plasma from a donor to a recipient or back to the donor. This process differs from the procedures undertaken in PLASMAPHERESIS and types of CYTAPHERESIS; (PLATELETPHERESIS and LEUKAPHERESIS) where, following the removal of plasma or the specific cell components, the remainder is transfused back to the donor.Blood Loss, Surgical: Loss of blood during a surgical procedure.Blood Transfusion, Intrauterine: In utero transfusion of BLOOD into the FETUS for the treatment of FETAL DISEASES, such as fetal erythroblastosis (ERYTHROBLASTOSIS, FETAL).Blood Banks: Centers for collecting, characterizing and storing human blood.Blood DonorsBlood Grouping and Crossmatching: Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion.Operative Blood Salvage: Recovery of blood lost from surgical procedures for reuse by the same patient in AUTOLOGOUS BLOOD TRANSFUSIONS. It is collected during (intraoperatively) or after completion of (postoperatively) the surgical procedures.Fetofetal Transfusion: Passage of blood from one fetus to another via an arteriovenous communication or other shunt, in a monozygotic twin pregnancy. It results in anemia in one twin and polycythemia in the other. (Lee et al., Wintrobe's Clinical Hematology, 9th ed, p737-8)Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.Postoperative Hemorrhage: Hemorrhage following any surgical procedure. It may be immediate or delayed and is not restricted to the surgical wound.Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.Hemoglobins: The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.Antifibrinolytic Agents: Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.Intraoperative Care: Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.Jehovah's Witnesses: Members of a religious denomination founded in the United States during the late 19th century in which active evangelism is practiced, the imminent approach of the millennium is preached, and war and organized government authority in matters of conscience are strongly opposed (from American Heritage Dictionary of the English Language, 4th ed). Jehovah's Witnesses generally refuse blood transfusions and other blood-based treatments based on religious belief.Blood Preservation: The process by which blood or its components are kept viable outside of the organism from which they are derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).Blood Group Incompatibility: An antigenic mismatch between donor and recipient blood. Antibodies present in the recipient's serum may be directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984).Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Blood Safety: The degree to which the blood supply for BLOOD TRANSFUSIONS is free of harmful substances or infectious agents, and properly typed and crossmatched (BLOOD GROUPING AND CROSSMATCHING) to insure serological compatibility between BLOOD DONORS and recipients.Anemia, Neonatal: The mildest form of erythroblastosis fetalis in which anemia is the chief manifestation.Leukocyte Transfusion: The transfer of leukocytes from a donor to a recipient or reinfusion to the donor.Hemodilution: Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.Perioperative Care: Interventions to provide care prior to, during, and immediately after surgery.Blood Substitutes: Substances that are used in place of blood, for example, as an alternative to BLOOD TRANSFUSIONS after blood loss to restore BLOOD VOLUME and oxygen-carrying capacity to the blood circulation, or to perfuse isolated organs.Plateletpheresis: The preparation of platelet concentrates with the return of red cells and platelet-poor plasma to the donor.beta-Thalassemia: A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.Erythroblastosis, Fetal: A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.Isoantibodies: Antibodies from an individual that react with ISOANTIGENS of another individual of the same species.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Hemostatics: Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure.Erythropoietin: Glycoprotein hormone, secreted chiefly by the KIDNEY in the adult and the LIVER in the FETUS, that acts on erythroid stem cells of the BONE MARROW to stimulate proliferation and differentiation.Leukocyte Reduction Procedures: The removal of LEUKOCYTES from BLOOD to reduce BLOOD TRANSFUSION reactions and lower the chance of transmitting VIRUSES. This may be performed by FILTRATION or by CYTAPHERESIS.Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.Hemorrhage: Bleeding or escape of blood from a vessel.Hemostasis, Surgical: Control of bleeding during or after surgery.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Preoperative Care: Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)Red Cross: International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Fetomaternal Transfusion: Transplacental passage of fetal blood into the circulation of the maternal organism. (Dorland, 27th ed)Surgical Procedures, Elective: Surgery which could be postponed or not done at all without danger to the patient. Elective surgery includes procedures to correct non-life-threatening medical problems as well as to alleviate conditions causing psychological stress or other potential risk to patients, e.g., cosmetic or contraceptive surgery.Blood-Borne Pathogens: Infectious organisms in the BLOOD, of which the predominant medical interest is their contamination of blood-soiled linens, towels, gowns, BANDAGES, other items from individuals in risk categories, NEEDLES and other sharp objects, MEDICAL WASTE and DENTAL WASTE, all of which health workers are exposed to. This concept is differentiated from the clinical conditions of BACTEREMIA; VIREMIA; and FUNGEMIA where the organism is present in the blood of a patient as the result of a natural infectious process.Cardiopulmonary Bypass: Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.Postoperative Care: The period of care beginning when the patient is removed from surgery and aimed at meeting the patient's psychological and physical needs directly after surgery. (From Dictionary of Health Services Management, 2d ed)Hepatitis C: INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally, and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.Rh Isoimmunization: The process by which fetal Rh+ erythrocytes enter the circulation of an Rh- mother, causing her to produce IMMUNOGLOBULIN G antibodies, which can cross the placenta and destroy the erythrocytes of Rh+ fetuses. Rh isoimmunization can also be caused by BLOOD TRANSFUSION with mismatched blood.Hematinics: Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.Aprotinin: A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)Arthroplasty, Replacement, Knee: Replacement of the knee joint.Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)Length of Stay: The period of confinement of a patient to a hospital or other health facility.Chelation Therapy: Therapy of heavy metal poisoning using agents which sequester the metal from organs or tissues and bind it firmly within the ring structure of a new compound which can be eliminated from the body.Cardiac Surgical Procedures: Surgery performed on the heart.Postpartum Hemorrhage: Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).Infant, Newborn: An infant during the first month after birth.Plasma: The residual portion of BLOOD that is left after removal of BLOOD CELLS by CENTRIFUGATION without prior BLOOD COAGULATION.Platelet Count: The number of PLATELETS per unit volume in a sample of venous BLOOD.Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.Thrombocytopenia: A subnormal level of BLOOD PLATELETS.Hepatitis C Antibodies: Antibodies to the HEPATITIS C ANTIGENS including antibodies to envelope, core, and non-structural proteins.Blood Coagulation Disorders: Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.Surgical Procedures, Operative: Operations carried out for the correction of deformities and defects, repair of injuries, and diagnosis and cure of certain diseases. (Taber, 18th ed.)Phlebotomy: The techniques used to draw blood from a vein for diagnostic purposes or for treatment of certain blood disorders such as erythrocytosis, hemochromatosis, polycythemia vera, and porphyria cutanea tarda.Hepatectomy: Excision of all or part of the liver. (Dorland, 28th ed)Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Reticulocyte Count: The number of RETICULOCYTES per unit volume of BLOOD. The values are expressed as a percentage of the ERYTHROCYTE COUNT or in the form of an index ("corrected reticulocyte index"), which attempts to account for the number of circulating erythrocytes.Hematocrit: The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Hepatitis, Viral, Human: INFLAMMATION of the LIVER in humans due to infection by VIRUSES. There are several significant types of human viral hepatitis with infection caused by enteric-transmission (HEPATITIS A; HEPATITIS E) or blood transfusion (HEPATITIS B; HEPATITIS C; and HEPATITIS D).Arthroplasty, Replacement, Hip: Replacement of the hip joint.Creutzfeldt-Jakob Syndrome: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))Peptic Ulcer Hemorrhage: Bleeding from a PEPTIC ULCER that can be located in any segment of the GASTROINTESTINAL TRACT.Seroepidemiologic Studies: EPIDEMIOLOGIC STUDIES based on the detection through serological testing of characteristic change in the serum level of specific ANTIBODIES. Latent subclinical infections and carrier states can thus be detected in addition to clinically overt cases.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Tattooing: The indelible marking of TISSUES, primarily SKIN, by pricking it with NEEDLES to imbed various COLORING AGENTS. Tattooing of the CORNEA is done to colorize LEUKOMA spots.Rh-Hr Blood-Group System: Erythrocyte isoantigens of the Rh (Rhesus) blood group system, the most complex of all human blood groups. The major antigen Rh or D is the most common cause of erythroblastosis fetalis.Iron Chelating Agents: Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems.Christianity: The religion stemming from the life, teachings, and death of Jesus Christ: the religion that believes in God as the Father Almighty who works redemptively through the Holy Spirit for men's salvation and that affirms Jesus Christ as Lord and Savior who proclaimed to man the gospel of salvation. (From Webster, 3d ed)Intraoperative Period: The period during a surgical operation.Fetoscopy: Endoscopic examination, therapy or surgery of the fetus and amniotic cavity through abdominal or uterine entry.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Intraoperative Complications: Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.Hepatitis B: INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Epistaxis: Bleeding from the nose.Drainage: The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.Blood Group Antigens: Sets of cell surface antigens located on BLOOD CELLS. They are usually membrane GLYCOPROTEINS or GLYCOLIPIDS that are antigenically distinguished by their carbohydrate moieties.Isotonic Solutions: Solutions having the same osmotic pressure as blood serum, or another solution with which they are compared. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)Infant, Premature: A human infant born before 37 weeks of GESTATION.Colonialism: The aggregate of various economic, political, and social policies by which an imperial power maintains or extends its control over other areas or peoples. It includes the practice of or belief in acquiring and retaining colonies. The emphasis is less on its identity as an ideological political system than on its designation in a period of history. (Webster, 3d ed; from Dr. J. Cassedy, NLM History of Medicine Division)Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.Erythrocyte Count: The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD.Plasma Substitutes: Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.Anemia, Hemolytic, Autoimmune: Acquired hemolytic anemia due to the presence of AUTOANTIBODIES which agglutinate or lyse the patient's own RED BLOOD CELLS.Coombs Test: A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.Thrombelastography: Use of a thrombelastograph, which provides a continuous graphic record of the physical shape of a clot during fibrin formation and subsequent lysis.Erythrocytes: Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.Hemosiderosis: Conditions in which there is a generalized increase in the iron stores of body tissues, particularly of liver and the MONONUCLEAR PHAGOCYTE SYSTEM, without demonstrable tissue damage. The name refers to the presence of stainable iron in the tissue in the form of hemosiderin.Hospital Mortality: A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).ABO Blood-Group System: The major human blood type system which depends on the presence or absence of two antigens A and B. Type O occurs when neither A nor B is present and AB when both are present. A and B are genetic factors that determine the presence of enzymes for the synthesis of certain glycoproteins mainly in the red cell membrane.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.Transplantation, Homologous: Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals.Nephrostomy, Percutaneous: The insertion of a catheter through the skin and body wall into the kidney pelvis, mainly to provide urine drainage where the ureter is not functional. It is used also to remove or dissolve renal calculi and to diagnose ureteral obstruction.Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Erythrocyte Aging: The senescence of RED BLOOD CELLS. Lacking the organelles that make protein synthesis possible, the mature erythrocyte is incapable of self-repair, reproduction, and carrying out certain functions performed by other cells. This limits the average life span of an erythrocyte to 120 days.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Perioperative Period: The time periods immediately before, during and following a surgical operation.Trauma Centers: Specialized hospital facilities which provide diagnostic and therapeutic services for trauma patients.Antisickling Agents: Agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle cell conditions.Vacuum: A space in which the pressure is far below atmospheric pressure so that the remaining gases do not affect processes being carried on in the space.Blood Cell Count: The number of LEUKOCYTES and ERYTHROCYTES per unit volume in a sample of venous BLOOD. A complete blood count (CBC) also includes measurement of the HEMOGLOBIN; HEMATOCRIT; and ERYTHROCYTE INDICES.Hemoglobinometry: Measurement of hemoglobin concentration in blood.Patient Identification Systems: Organized procedures for establishing patient identity, including use of bracelets, etc.Fibrin Tissue Adhesive: An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.Laparoscopy: A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.Shock, Hemorrhagic: Acute hemorrhage or excessive fluid loss resulting in HYPOVOLEMIA.Medical Audit: A detailed review and evaluation of selected clinical records by qualified professional personnel for evaluating quality of medical care.Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.Splenectomy: Surgical procedure involving either partial or entire removal of the spleen.Jaundice, Neonatal: Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.Papilloma, Inverted: A mucosal tumor of the urinary bladder or nasal cavity in which proliferating epithelium is invaginated beneath the surface and is more smoothly rounded than in other papillomas. (Stedman, 25th ed)Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.Blood Specimen Collection: The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Angiodysplasia: Acquired degenerative dilation or expansion (ectasia) of normal BLOOD VESSELS, often associated with aging. They are isolated, tortuous, thin-walled vessels and sources of bleeding. They occur most often in mucosal capillaries of the GASTROINTESTINAL TRACT leading to GASTROINTESTINAL HEMORRHAGE and ANEMIA.Babesia microti: A species of protozoa infecting humans via the intermediate tick vector IXODES scapularis. The other hosts are the mouse PEROMYSCUS leucopus and meadow vole MICROTUS pennsylvanicus, which are fed on by the tick. Other primates can be experimentally infected with Babesia microti.Blood Volume: Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.Critical Illness: A disease or state in which death is possible or imminent.Iron Compounds: Organic and inorganic compounds that contain iron as an integral part of the molecule.Filtration: A process of separating particulate matter from a fluid, such as air or a liquid, by passing the fluid carrier through a medium that will not pass the particulates. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Resuscitation: The restoration to life or consciousness of one apparently dead. (Dorland, 27th ed)Iron: A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.Graft Survival: The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.Otorhinolaryngologic Surgical Procedures: Surgery performed on the ear and its parts, the nose and nasal cavity, or the throat, including surgery of the adenoids, tonsils, pharynx, and trachea.Melena: The black, tarry, foul-smelling FECES that contain degraded blood.Disease Transmission, Infectious: The transmission of infectious disease or pathogens. When transmission is within the same species, the mode can be horizontal or vertical (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).Renal Dialysis: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.Blood Coagulation Tests: Laboratory tests for evaluating the individual's clotting mechanism.Nigeria: A republic in western Africa, south of NIGER between BENIN and CAMEROON. Its capital is Abuja.Military Medicine: The practice of medicine as applied to special circumstances associated with military operations.Flaviviridae: A family of RNA viruses, many of which cause disease in humans and domestic animals. There are three genera FLAVIVIRUS; PESTIVIRUS; and HEPACIVIRUS, as well as several unassigned species.Hemostatic Techniques: Techniques for controlling bleeding.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).Hepacivirus: A genus of FLAVIVIRIDAE causing parenterally-transmitted HEPATITIS C which is associated with transfusions and drug abuse. Hepatitis C virus is the type species.Kell Blood-Group System: Multiple erythrocytic antigens that comprise at least three pairs of alternates and amorphs, determined by one complex gene or possibly several genes at closely linked loci. The system is important in transfusion reactions. Its expression involves the X-chromosome.Micropore Filters: A membrane or barrier with micrometer sized pores used for separation purification processes.Clinical Protocols: Precise and detailed plans for the study of a medical or biomedical problem and/or plans for a regimen of therapy.Infant, Premature, DiseasesStatistics, Nonparametric: A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)Blood Platelets: Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.Kidney Transplantation: The transference of a kidney from one human or animal to another.Injury Severity Score: An anatomic severity scale based on the Abbreviated Injury Scale (AIS) and developed specifically to score multiple traumatic injuries. It has been used as a predictor of mortality.Hepatitis B Surface Antigens: Those hepatitis B antigens found on the surface of the Dane particle and on the 20 nm spherical and tubular particles. Several subspecificities of the surface antigen are known. These were formerly called the Australia antigen.Isoantigens: Antigens that exist in alternative (allelic) forms in a single species. When an isoantigen is encountered by species members who lack it, an immune response is induced. Typical isoantigens are the BLOOD GROUP ANTIGENS.Coronary Artery Bypass: Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.Hepatitis Antibodies: Immunoglobulins raised by any form of viral hepatitis; some of these antibodies are used to diagnose the specific kind of hepatitis.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Intensive Care: Advanced and highly specialized care provided to medical or surgical patients whose conditions are life-threatening and require comprehensive care and constant monitoring. It is usually administered in specially equipped units of a health care facility.Abbreviations as Topic: Shortened forms of written words or phrases used for brevity.Wounds, Nonpenetrating: Injuries caused by impact with a blunt object where there is no penetration of the skin.Priapism: A prolonged painful erection that may lasts hours and is not associated with sexual activity. It is seen in patients with SICKLE CELL ANEMIA, advanced malignancy, spinal trauma; and certain drug treatments.Multiple Trauma: Multiple physical insults or injuries occurring simultaneously.Multiple Organ Failure: A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.Ferritins: Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their major function is to store IRON in a nontoxic bioavailable form. Each ferritin molecule consists of ferric iron in a hollow protein shell (APOFERRITINS) made of 24 subunits of various sequences depending on the species and tissue types.Hospitals, University: Hospitals maintained by a university for the teaching of medical students, postgraduate training programs, and clinical research.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Babesiosis: A group of tick-borne diseases of mammals including ZOONOSES in humans. They are caused by protozoa of the genus BABESIA, which parasitize erythrocytes, producing hemolysis. In the U.S., the organism's natural host is mice and transmission is by the deer tick IXODES SCAPULARIS.Histocompatibility Testing: Identification of the major histocompatibility antigens of transplant DONORS and potential recipients, usually by serological tests. Donor and recipient pairs should be of identical ABO blood group, and in addition should be matched as closely as possible for HISTOCOMPATIBILITY ANTIGENS in order to minimize the likelihood of allograft rejection. (King, Dictionary of Genetics, 4th ed)Critical Care: Health care provided to a critically ill patient during a medical emergency or crisis.Liver Neoplasms: Tumors or cancer of the LIVER.HLA Antigens: Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.Hydroxyethyl Starch Derivatives: Starches that have been chemically modified so that a percentage of OH groups are substituted with 2-hydroxyethyl ether groups.Hemoperitoneum: Accumulations of blood in the PERITONEAL CAVITY due to internal HEMORRHAGE.Postoperative Period: The period following a surgical operation.

Reduction in baroreflex cardiovascular responses due to venous infusion in the rabbit. (1/3107)

We studied reflex bradycardia and depression of mean arterial blood pressure (MAP) during left aortic nerve (LAN) stimulation before and after volume infusion in the anesthetized rabbit. Step increases in mean right atrial pressure (MRAP) to 10 mm Hg did not result in a significant change in heart rate or MAP. After volume loading, responses to LAN stimulation were not as great and the degree of attenuation was propoetional to the level of increased MRAP. A change in responsiveness was observed after elevation of MRAP by only 1 mm Hg, corresponding to less than a 10% increase in average calculated blood volume. after an increase in MRAP of 10 mm Hg, peak responses were attenuated by 44% (heart rate) and 52% (MAP), and the initial slopes (rate of change) were reduced by 46% (heart rate) and 66% (MAP). Comparison of the responses after infusion with blood and dextran solutions indicated that hemodilution was an unlikely explanation for the attenuation of the reflex responses. Total arterial baroreceptor denervation (ABD) abolished the volume-related attenuation was still present following bilateral aortic nerve section or vagotomy. It thus appears that the carotid sinus responds to changes inblood volume and influences the reflex cardiovascular responses to afferent stimulation of the LAN. On the other hand, cardiopulmonary receptors subserved by vagal afferents do not appear to be involved.  (+info)

A prospective study on TT virus infection in transfusion-dependent patients with beta-thalassemia. (2/3107)

A novel DNA virus designated TT virus (TTV) has been reported to be involved in the development of posttransfusion non-A-C hepatitis. We evaluated the frequency and natural course of TTV infection in a cohort of transfusion-dependent thalassemic patients in a 3-year follow-up study. Ninety-three serum hepatitis C virus (HCV) antibody-negative patients (median age of 8 years; range, 0 to 25) from eight centers were studied. Of them, 34 (37%) had an abnormal alanine-aminotransferase (ALT) baseline pattern, and the other 12 (13%) showed ALT flare-ups during the follow-up. TTV DNA in patient sera collected at the time of enrollment and at the end of follow-up was determined by polymerase chain reaction (PCR). In parallel, serum samples from 100 healthy blood donors were also tested. At baseline, 87 patient sera (93.5%) tested positive for the TTV DNA. Of these TTV DNA-positive patients, 84 (96.5%) remained viremic at the end of the study period. Of the 6 TTV DNA-negative patients, 3 acquired TTV infection during follow-up. However, no definite relation was observed between the results of TTV DNA determination and ALT patterns. TTV viremia was also detectable in 22% of blood donors. In conclusion, TTV infection is frequent and persistent among Italian transfusion-dependent patients. The high rate of viremia observed in healthy donors indicates that the parenteral route is not the only mode of TTV spread.  (+info)

Soluble HLA class I, HLA class II, and Fas ligand in blood components: a possible key to explain the immunomodulatory effects of allogeneic blood transfusions. (3/3107)

The immunomodulatory effect of allogeneic blood transfusions (ABT) has been known for many years. However, a complete understanding of the effects of ABT on the recipient's immune system has remained elusive. Soluble HLA class I (sHLA-I), HLA class II (sHLA-II), and Fas ligand (sFasL) molecules may play immunoregulatory roles. We determined by double-determinant immunoenzymatic assay (DDIA) sHLA-I, sHLA-II, and sFasL concentrations in different blood components. sHLA-I and sFasL levels in red blood cells (RBCs) stored for up to 30 days and in random-donor platelets are significantly (P <.001) higher than in other blood components and their amount is proportionate to the number of residual donor leukocytes and to the length of storage. Blood components with high sHLA-I and sFasL levels play immunoregulatory roles in vitro as in allogeneic mixed lymphocyte responses (MLR) and antigen-specific cytotoxic T-cell (CTL) activity, and induce apoptosis in Fas-positive cells. These data suggest that soluble molecules in blood components are functional. If these results are paralleled in vivo, they should be taken into account in transfusion practice. Blood components that can cause immunosuppression should be chosen to induce transplantation tolerance, whereas blood components that lack immunosuppressive effects should be preferred to reduce the risk of postoperative complications and cancer recurrence.  (+info)

Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly(ethylene glycol). (4/3107)

We previously showed that the covalent modification of the red blood cell (RBC) surface with methoxypoly(ethylene glycol) [mPEG; MW approximately 5 kD] could significantly attenuate the immunologic recognition of surface antigens. However, to make these antigenically silent RBC a clinically viable option, the mPEG-modified RBC must maintain normal cellular structure and functions. To this end, mPEG-derivatization was found to have no significant detrimental effects on RBC structure or function at concentrations that effectively blocked antigenic recognition of a variety of RBC antigens. Importantly, RBC lysis, morphology, and hemoglobin oxidation state were unaffected by mPEG-modification. Furthermore, as shown by functional studies of Band 3, a major site of modification, PEG-binding does not affect protein function, as evidenced by normal SO4- flux. Similarly, Na+ and K+ homeostasis were unaffected. The functional aspects of the mPEG-modified RBC were also maintained, as evidenced by normal oxygen binding and cellular deformability. Perhaps most importantly, mPEG-derivatized mouse RBC showed normal in vivo survival ( approximately 50 days) with no sensitization after repeated transfusions. These data further support the hypothesis that the covalent attachment of nonimmunogenic materials (eg, mPEG) to intact RBC may have significant application in transfusion medicine, especially for the chronically transfused and/or allosensitized patient.  (+info)

Endoscopic retreatment compared with surgery in patients with recurrent bleeding after initial endoscopic control of bleeding ulcers. (5/3107)

BACKGROUND AND METHODS: After endoscopic treatment to control bleeding of peptic ulcers, bleeding recurs in 15 to 20 percent of patients. In a prospective, randomized study, we compared endoscopic retreatment with surgery after initial endoscopy. Over a 40-month period, 1169 of 3473 adults who were admitted to our hospital with bleeding peptic ulcers underwent endoscopy to reestablish hemostasis. Of 100 patients with recurrent bleeding, 7 patients with cancer and 1 patient with cardiac arrest were excluded from the study; 48 patients were randomly assigned to undergo immediate endoscopic retreatment and 44 were assigned to undergo surgery. The type of operation used was left to the surgeon. Bleeding was considered to have recurred in the event of any one of the following: vomiting of fresh blood, hypotension and melena, or a requirement for more than four units of blood in the 72-hour period after endoscopic treatment. RESULTS: Of the 48 patients who were assigned to endoscopic retreatment, 35 had long-term control of bleeding. Thirteen underwent salvage surgery, 11 because retreatment failed and 2 because of perforations resulting from thermocoagulation. Five patients in the endoscopy group died within 30 days, as compared with eight patients in the surgery group (P=0.37). Seven patients in the endoscopy group (including 6 who underwent salvage surgery) had complications, as compared with 16 in the surgery group (P=0.03). The duration of hospitalization, the need for hospitalization in the intensive care unit and the resultant duration of that stay, and the number of blood transfusions were similar in the two groups. In multivariate analysis, hypotension at randomization (P=0.01) and an ulcer size of at least 2 cm (P=0.03) were independent factors predictive of the failure of endoscopic retreatment. CONCLUSIONS: In patients with peptic ulcers and recurrent bleeding after initial endoscopic control of bleeding, endoscopic retreatment reduces the need for surgery without increasing the risk of death and is associated with fewer complications than is surgery.  (+info)

Primary percutaneous transluminal coronary angioplasty performed for acute myocardial infarction in a patient with idiopathic thrombocytopenic purpura. (6/3107)

A 72-year-old female with idiopathic thrombocytopenic purpura (ITP) complained of severe chest pain. Electrocardiography showed ST-segment depression and negative T wave in I, aVL and V4-6. Following a diagnosis of acute myocardial infarction (AMI), urgent coronary angiography revealed 99% organic stenosis with delayed flow in the proximal segment and 50% in the middle segment of the left anterior descending artery (LAD). Subsequently, percutaneous transluminal coronary angioplasty (PTCA) for the stenosis in the proximal LAD was performed. In the coronary care unit, her blood pressure dropped. Hematomas around the puncture sites were observed and the platelet count was 28,000/mm3. After transfusion, electrocardiography revealed ST-segment elevation in I, aVL and V1-6. Urgent recatheterization disclosed total occlusion in the middle segment of the LAD. Subsequently, PTCA was performed successfully. Then, intravenous immunoglobulin increased the platelet count and the bleeding tendency disappeared. A case of AMI with ITP is rare. The present case suggests that primary PTCA can be a useful therapeutic strategy, but careful attention must be paid to hemostasis and to managing the platelet count.  (+info)

Hormonal changes in thalassaemia major. (7/3107)

Patients with severe thalassaemia major suffer endocrine and other abnormalities before their eventual death from iron overload due to repeated blood transfusions. The endocrine status of 31 thalassaemic patients aged 2-5 to 23 years was investigated. Exact data were available on the rate and duration of blood transfusion in all of them and in many the liver iron concentration was also known. Although the patients were euthyroid, the mean serum thyroxine level was significantly lower, and the mean thyrotrophic hormone level significantly higher, compared with the values found in normal children. Forty oral glucose tolerance tests with simultaneous insulin levels were performed in 19 children, of whom 5 developed symptomatic diabetes and one had impaired tolerance. Previous tests on all 6 patients were available and some showed raised insulin levels possibly due to insulin resistance. 2 patients had clinical hypoparathyroidism and are described. The parathyroid hormone levels determined by radioimmunoassay in 25 patients were below the mean for the age group in all and outside the reference range in 16. Nonfasting plasma calcium levels were not reduced. Puberty was delayed in some patients. Concentrations of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) measured in urine from 7 girls and 5 boys showed considerable variation. In the boys there was an overall tendency for FSH and LH excretion to be low with regard to age, but with respect to puberty rating FSH exretions were normal or low and LH normal or raised. The girls showed a tendency for LH but not FSH excretion to be raised in relation to puberty rating. The severity of the endocrine changes was related to the degree of iron loading and is discussed in relation to previous work in which the iron loading has rarely been accurately indicated nor parathyroid status assessed.  (+info)

Prospective randomized multicenter study comparing cyclosporin alone versus the combination of antithymocyte globulin and cyclosporin for treatment of patients with nonsevere aplastic anemia: a report from the European Blood and Marrow Transplant (EBMT) Severe Aplastic Anaemia Working Party. (8/3107)

We report the results of the first prospective randomized multicenter study of immunosuppressive treatment in patients with previously untreated nonsevere aplastic anemia (AA) as defined by a neutrophil count of at least 0.5 x 10(9)/L and transfusion dependence. Patients were randomized to receive cyclosporin (CSA) alone or the combination of horse antithymocyte globulin ([ATG] Lymphoglobuline; Merieux, Lyon, France) and CSA. The endpoint of the study was the hematologic response at 6 months. One hundred fifteen patients were randomized and assessable with a median follow-up period of 36 months; 61 received CSA and 54 ATG and CSA. In the CSA group, the percentage of complete and partial responders was 23% and 23%, respectively, for an overall response rate of 46%. A significantly higher overall response rate of 74% was found in the ATG and CSA group, with 57% complete and 17% partial responders (P =. 02). Compared with CSA alone, the combination of ATG and CSA resulted in a significantly higher median hemoglobin level and platelet count at 6 months. Fewer patients required a second course of treatment before 6 months due to a nonresponse. In the CSA group, 15 of 61 (25%) patients required a course of ATG before 6 months because of disease progression, compared with only 3 of 54 (6%) in the ATG and CSA group. The survival probabilities for the two groups were comparable, 93% (CSA group) and 91% (ATG and CSA group), but at 180 days, the prevalence of patients surviving free of transfusions, which excluded patients requiring second treatment because of nonresponse, death, disease progression, or relapse, was 67% in the CSA group and 90% in the ATG and CSA group (P =.001). We conclude that the combination of ATG and CSA is superior to CSA alone in terms of the hematologic response, the quality of response, and early mortality, and a second course of immunosuppression is less frequently required.  (+info)

*Blood transfusion

American Association of Blood Banks (AABB) British Blood Transfusion Society (BBTS) International Society of Blood Transfusion ... Blood transfusions fell into obscurity for the next 150 years. The science of blood transfusion dates to the first decade of ... Early transfusions used whole blood, but modern medical practice commonly uses only components of the blood, such as red blood ... Blood transfusion is generally the process of receiving blood or blood products into one's circulation intravenously. ...

*Cadaveric blood transfusion

... is the transfusion of blood from a dead body to a living person. In 1929, professor Vladimir Shamov ... Blood transfusion from cadaver, Trudi Ukrain. Suezda. Khir. 1929;18:184. Shamov WN. The transfusion of stored cadaver blood ... Transfusion of cadaver blood. JAMA 1936;106:997-9. Swan H, Schechter D. The transfusion of blood from cadavers. A historical ... Transfusion of Human Corps Blood without Additives.Transfusion. 1964;4:112-7. www.anes.uab.edu. ...

*Irish Blood Transfusion Service

"Irish Blood Transfusion Service - Irish Blood Group Type Frequency Distribution". Irish Blood Transfusion Service. Retrieved 7 ... The Service provides blood and blood products for humans. The service is the successor to the National Blood Transfusion ... In 1975 the Cork Blood Transfusion Service was amalgamated with the board, and in 1991 the Limerick Blood Transfusion Service ... was established in Ireland as the Blood Transfusion Service Board (BTSB) by the Blood Transfusion Service Board (Establishment ...

*Blood transfusion in Sri Lanka

"Safe Blood for Saving Mothers". "History of Blood Transfusion Service in Sri Lanka". National Blood Transfusion Service of Sri ... Mobile blood donation programs were initiated with two mobile blood collection teams. In 1981, the NHSL's blood bank (then ... Blood transfusion was first performed in Sri Lanka in late 1950. It became more widely known to the public in 1959 after the ... blood was collected into glass bottles and collected blood was screened only for malaria and syphilis. Hospital-based blood ...

*Scottish National Blood Transfusion Service

The Scottish National Blood Transfusion Service (SNBTS) is the national blood, blood product and tissue provider. It makes up a ... Blood donation Blood transfusion James Blundell (physician) Emergency Hospital Service NHS Blood and Transplant - the ... Masson, Alastair (1993). History of the Blood Transfusion Service in Edinburgh. Edinburgh. p. 99. "Blood transfusion service to ... The Edinburgh Blood Transfusion Service (EBTS) was established in 1936 with Jack Copland as Organiser and Helen White as ...

*International Society of Blood Transfusion

... which aims to promote the study of blood transfusion, and to spread the know-how about the manner in which blood transfusion ... Blood transfusion was a rather new therapeutic option, and therefore it was decided that transfusion-specific congresses should ... ISBT advocates standardisation and harmonisation in the field of blood transfusion. The other major impact on the transfusion ... The formation of the International Society of Blood Transfusion, or Societé International de Transfusion Sanguine, as it was ...

*Northern Ireland Blood Transfusion Service

... responsible for collecting blood and providing a supply to hospitals in the country. An emergency Blood Transfusion Service was ... The Northern Ireland Blood Transfusion Service (NIBTS) is an independent, special agency of the Department of Health in ... "History of the service". Northern Ireland Blood Transfusion Service. 2014. Retrieved 30 December 2014. Official website. ...

*Jehovah's Witnesses and blood transfusions

Blood introduced directly into the veins circulates and functions as blood, not as nutrition. Hence, blood transfusion is a ... In 1945, the application of the doctrine on blood was expanded to prohibit blood transfusions of whole blood, whether ... This includes the use of red blood cells, white blood cells, platelets and blood plasma. Other fractions derived from blood are ... ingesting blood and that Christians should not accept blood transfusions or donate or store their own blood for transfusion. ...

*Islami Bank Medical College

Pediatrics • Surgery • Cardiology • Psychiatry • Physical Medicine • Blood Transfusion • Gastroenterology • Orthopedic • ...

*Anne Poor

Works from this time include Restraining Psychotic at Holding Station, Guam; Blood Transfusion; Dying Boy and Walking Wounded. ...

*Giant platelet disorder

Blood Transfusion. 7 (4): 278-292. doi:10.2450/2009.0078-08. ISSN 1723-2007. PMC 2782805 . PMID 20011639. "Bernard-Soulier ... Platelet transfusion is the main treatment for people presenting with bleeding symptoms. There have been experiments with DDAVP ... Giant platelets cannot stick adequately to an injured blood vessel walls, resulting in abnormal bleeding when injured. Giant ... Abnormality of the abdomen, nosebleeds, heavy menstrual bleeding, purpura, too few platelets circulating in the blood, and ...

*Jean-Baptiste Denys

He received two transfusions, and died after the second. In the winter of 1667, Denys administered transfusions of calf's blood ... It wasn't until after Karl Landsteiner's discovery of the four blood groups in 1902 that blood transfusions became safe and ... "The First Blood Transfusion?". Heart-valve-surgery.com. 2009-01-03. Retrieved 2010-02-09. "Red Gold . Innovators & Pioneers . ... Denys administered the first fully documented human blood transfusion on June 15, 1667. He transfused about twelve ounces of ...

*Thrombocytopenia

Other blood thinners sometimes used in this setting include bivalirudin and fondaparinux. Platelet transfusions are not ... It is also important to ensure that the other blood cell types, such as red blood cells and white blood cells, are not also ... Smit-Sibinga, C. Th (2010-05-10). Neonatology and Blood Transfusion. Springer Science & Business Media. ISBN 9780387236001. ... Thrombocytopenia usually has no symptoms and is picked up on a routine full blood count (or complete blood count). Some ...

*Tranexamic acid

"Tranexamic acid". Clinical Transfusion. International Society of Blood Transfusion (ISBT). "Lysteda (tranexamic acid) Package ... In surgical corrections of craniosynostosis in children it reduces the need for blood transfusions. In spinal surgery (e.g., ... a short period of time before and after the surgery to prevent major blood loss and decrease the need for blood transfusions. ... Journal of Blood Transfusion. 2015: 874920. doi:10.1155/2015/874920. PMC 4576020 . PMID 26448897. Melvin JS, Stryker LS, Sierra ...

*Paul Terasaki

Effect of blood transfusions on subsequent kidney transplants. Transplant Proc 1973; 4: 253-259. Terasaki PI, Cho YW, Cecka JM ... 1982). Blood transfusion and transplantation. New York: Grune & Stratton. ISBN 0-8089-1522-3. Retrieved 2008-12-13. Stuart ...

*Pelican

The symbol of the Irish Blood Transfusion Service is a pelican, and for most of its existence the headquarters of the service ... "Irish Blood Transfusion Service". IBTS. Retrieved 13 June 2012. Rothwell, David (2006). Dictionary of Pub Names. London, United ... An older version of the myth is that the pelican used to kill its young then resurrect them with its blood, again analogous to ... The legends of self-wounding and the provision of blood may have arisen because of the impression a pelican sometimes gives ...

*Mujibur Rahman (scientist)

... in hematology and blood transfusion from South and Southeast Asia. After returning from Glasgow, Rahman served as the blood ... He set up 30 blood transfusion centres during his time in public service. He became an honorary member of the World Health ... He set up the Blood Transfusion Society in Bangladesh and acted as its president. Rahman wrote six books. He published research ... He established the first blood transfusion center at the Institute of Post Graduate Medicine and Research (now Bangabandhu ...

*OSF St. Joseph Medical Center

... the 1929 first blood transfusion; first successful radiation therapy in the 1940s; the 1990 first open heart surgery; and first ...

*Chikungunya

2008). "The Chikungunya epidemic in Italy and its repercussion on the blood system". Blood Transfusion = Trasfusione Del Sangue ... RT-PCR can also be used to quantify the viral load in the blood. Using RT-PCR, diagnostic results can be available in one to ... Fever occurs with the onset of viremia, and the level of virus in the blood correlates with the intensity of symptoms in the ... Because high amounts of virus are present in the blood in the beginning of acute infection, the virus can be spread from a ...

*Health Sciences Authority

As a WHO Collaborating Centre, the agency is an appointed Regional Quality Management Training Centre for Blood Transfusion ... The Blood Services Group is the national blood service of Singapore and is responsible for the adequacy and safety of the ... The framework covers the recruitment of voluntary non-remunerated blood donors, stringent blood donation screening criteria, a ... and Singapore Blood Transfusion Service. Today, the agency's professional knowledge, skills and competencies are housed in ...

*Patrick Mollison

He was Director of the Medical Research Council's Blood Transfusion Research Unit (later the Experimental Haematology Unit), ... Blood transfusion in clinical medicine. Blackwell Scientific Publications. "Munks Roll Details for Patrick Loudon Mollison". ... Mollison, P; Loutit, J (1943). "Disodium-citrate-glucose mixture as a blood preservative". British Medical Journal (2): 744-745 ... the father of transfusion medicine'. Mollison was born on 17 March 1914, to Beatrice Marjorie, née Walker, and William Mayhew ...

*West Nile fever

... or conjunctive exposure to infected blood. The US outbreak identified additional transmission methods through blood transfusion ... Scottish National Blood Transfusion Service. "West Nile virus". Mayo Clinic. Archived from the original on 26 October 2017. ... Rarely the virus is spread through blood transfusions, organ transplants, or from mother to baby during pregnancy, delivery, or ... Centers for Disease Control and Prevention (CDC) (2002). "Investigation of blood transfusion recipients with West Nile virus ...

*Riboflavin

"Improving the safety of whole blood-derived transfusion products with a riboflavin-based pathogen reduction technology". Blood ... As of 2017 a system is marketed by Terumo in Europe that is used to remove pathogens from blood; donated blood is treated with ... Lane M, Alfrey CP (Apr 1965). "THE ANEMIA OF HUMAN RIBOFLAVIN DEFICIENCY". Blood. 25: 432-442. PMID 14284333. Smedts HP, ... which causes anemia with large blood cells (megaloblastic anemia). Deficiency of riboflavin during pregnancy can result in ...

*MNS antigen system

"Table of blood group antigens within systems". International Society for Blood Transfusion. Archived from the original on 2011- ... Blood Group Antibodies and Their Significance in Transfusion Medicine. Transfus Med Rev 2007; 21: 58-71. Daniels G. Human Blood ... International Society of Blood Transfusion Committee on Terminology for Red Cell Surface Antigens: Cape Town Report. Vox Sang ... Anti-S, anti-s and anti-U antibodies are acquired following exposure (via pregnancy or past transfusion with blood products) ...

*Royal Infirmary of Edinburgh

Scottish National Blood Transfusion Service. Retrieved 28 November 2014. Henley W E (1875): Hospital Outlines: Sketches and ... "Transplant Units". NHS Blood and Transplant. Retrieved 24 February 2014. "TAVI Accredited Centres" (PDF). Edwards Lifesciences ...

*Childbirth

Blood transfusion may be life saving. Rare sequelae include Hypopituitarism Sheehan's syndrome. The maternal mortality rate ( ... blood pressure(rarely taken on newborns in the pre-hospital setting) oxygen saturation, blood sugar, and EKG monitoring. They ... Hemorrhage, or heavy blood loss, is still the leading cause of death of birthing mothers in the world today, especially in the ... Heavy blood loss leads to hypovolemic shock, insufficient perfusion of vital organs and death if not rapidly treated. ...
TY - JOUR. T1 - Early autologous fresh whole blood transfusion leads to less allogeneic transfusions and is safe. AU - Rhee, Peter. AU - Inaba, Kenji. AU - Pandit, Viraj. AU - Khalil, Mazhar. AU - Siboni, Stefano. AU - Vercruysse, Gary. AU - Kulvatunyou, Narong. AU - Tang, Andrew. AU - Asif, Anum. AU - OKeeffe, Terence. AU - Joseph, Bellal. PY - 2015/4/4. Y1 - 2015/4/4. N2 - BACKGROUND: The practice of transfusing ones own shed whole blood has obvious benefits such as reducing the need for allogeneic transfusions and decreasing the need for other fluids that are typically used for resuscitation in trauma. It is not widely adopted in the trauma setting because of the concern of worsening coagulopathy and the inflammatory process. The aim of this study was to assess outcomes in trauma patients receiving whole blood autotransfusion (AT) from hemothorax. METHODS: This is a multi-institutional retrospective study of all trauma patients who received autologous whole blood transfusion from hemothorax ...
TY - JOUR. T1 - Cancer incidence in blood transfusion recipients.. AU - Hjalgrim, Henrik. AU - Edgren, Gustaf. AU - Rostgaard, Klaus. AU - Reilly, Marie. AU - Tran, Trung Nam. AU - Titlestad, Kjell. AU - Shanwell, Agneta. AU - Jersild, Casper. AU - Adami, Johanna. AU - Wikman, Agneta. AU - Gridley, Gloria. AU - Wideroff, Louise. AU - Nyrén, Olof. AU - Melbye, Mads. PY - 2007/12/19. Y1 - 2007/12/19. N2 - BACKGROUND: Blood transfusions may influence the recipients cancer risks both through transmission of biologic agents and by modulation of the immune system. However, cancer occurrence in transfusion recipients remains poorly characterized. METHODS: We used computerized files from Scandinavian blood banks to identify a cohort of 888,843 cancer-free recipients transfused after 1968. The recipients were followed from first registered transfusion until the date of death, emigration, cancer diagnosis, or December 31, 2002, whichever came first. Relative risks were expressed as ratios of the ...
HIV THROUGH BLOOD TRANSFUSION. In the event that the insured contracted HIV as a result of blood transfusion, 10% on the Principal Sum Insured is payable. If you wish to apply for The Personal Sentinel coverage, just instruct us by e-mail providing the following details and we will be sending you the appropriate Application Form:-. ...
Blood transfusion is administered during many types of surgery, but its efficacy and safety are increasingly questioned. Evaluation of the efficacy of agents, such as desmopressin (DDAVP; 1-deamino-8-D-arginine-vasopressin), that may reduce perioperative blood loss is needed.To examine the evidence for the efficacy of DDAVP in reducing perioperative blood loss and the need for red cell transfusion in people who do not have inherited bleeding disorders.We searched for randomised controlled trials (RCTs) in the Cochrane Central Register of Controlled Trials (2017, issue 3) in the Cochrane Library, MEDLINE (from 1946), Embase (from 1974), the Cumulative Index to Nursing and Allied Health Literature (CINAHL) (from 1937), the Transfusion Evidence Library (from 1980), and ongoing trial databases (all searches to 3 April 2017).We included randomised controlled trials comparing DDAVP to placebo or an active comparator (e.g. tranexamic acid, aprotinin) before, during, or immediately after surgery or after
Transfusion of washed intra-operative cell salvage post-operatively in the PCICU can be performed safely without increased risk of bleeding or release of inflammatory mediators. This will reduce the need for allogeneic blood products as well as crystalloid and colloid infusions and thus decrease the length of ventilation and intensive care duration for these infants ...
by Vetscite. Blood transfusions are one of the most common procedures patients receive in the hospital but the more red blood cells they receive, the greater their risk of infection, says a new study led by the University of Michigan Heath System and VA Ann Arbor Healthcare System. Researchers analyzed 21 randomized controlled trials for the study that appears in Journal of the American Medical Association (JAMA). Elderly patients undergoing hip or knee surgeries were most susceptible, with a 30 percent lower risk of infection when fewer transfusions were used. Overall, for every 38 hospitalized patients considered for a red blood cell transfusion (RBC), one patient would be spared a serious infection if fewer transfusions were used. Transfusions are often used for anemia or during surgery to make up for blood loss. The authors evaluated all health care-associated infections that were reported after receiving donor blood in the randomized trials. These included serious infections such as ...
As French physicians frequently and currently deployed in Theater of Operations in Africa, we read with interest the article by Ariyo et al.1 reviewing the anesthesia care provided at Médecins Sans Frontières facilities between 2008 and 2014. Spinal anesthesia was the most common type of anesthetic technique (34,413 [45.56%]), with cesarean section being the most common type of procedure performed (26,091 [34.54%]). Wound surgeries represented another common procedure type included in this retrospective study (18,547 [24.55%]). In this context, perioperative deaths occurred in 72 (0.21%) cases of obstetrics/gynecology and urology surgery and in only seven (0.06%) cases of wound surgeries. Nevertheless, the authors did not provide any details regarding the causes of death or any details about the incidence of perioperative bleeding and perioperative blood management. Perioperative blood management refers to perioperative blood transfusion and adjuvant therapies.2 Perioperative blood transfusion ...
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Background: Despite the minimally invasive nature of trans-catheter aortic valve implantation (TAVI), the procedure is associated with several complications. We analyzed the individual impact of bleeding events, hemoglobin (Hb) drop, and Red Blood Cells (RBC) transfusions on prognosis.. Methods and results: Consecutive patients (n=597) undergoing trans-femoral TAVI were prospectively enrolled. Peri-procedural Hb levels, RBC transfusions and major/life threatening bleeding events were documented and analyzed. To study the relationship between Hb drop, RBC transfusions and long-term mortality, the entire cohort was divided into 4 groups according to Hb drop (less or ≥ than 3 g/dl), and receiving RBC transfusion (yes /no). In the entire cohort mean Hb level decreased following TAVI (11.8±1.4 to 9.5 ±1.3 g/dl; p,0.001). Major/ life threatening bleedings occurred in 66 (10.1%) patients, and 179 (30%) patients received RBC transfusions. Major/life threatening bleedings were not independently ...
Conclusions There is a lack of current guidelines outlining when to give terminally ill cancer patients a blood transfusion, due to the fact that every patient needs to be individually assessed. Generally, attitudes towards blood transfusions were positive; most thought that suffering was an appropriate reason for a blood transfusion. The large majority did not think that blood transfusions should be withheld. Attitudes towards blood transfusions with palliative intent were slightly more positive in oncology compared to palliative care healthcare professionals.. ...
BACKGROUND: Open simple prostatectomy has long been associated with large blood losses; hence allogeneic blood transfusion in this procedure is a standard practice world over. A review of literature suggests significant association between perioperative blood loss accompanying open simple prostatectomy and certain patient factors. The shortage of blood and blood products in our blood transfusion centres as well as the alarming risks of transfusion reactions and disease dissemination demanded a review of these factors with the aim of reducing morbidity associated with peri-operative blood loss and blood transfusion. OBJECTIVES: To assess blood loss, determine blood transfusion rate, and define some of the factors associated with peri-operative blood loss and blood transfusion in open simple prostatectomy. DESIGN : A prospective cohort study. SETTINGS: The urology units of Kenyatta National Hospital, Kenya. RESULTS: Ninety five patients who underwent open simple prostatectomy for benign prostatic ...
Some time ago my delightful 80+ year-old grandmother was diagnosed with a GI bleed that led to hospitalization and multiple transfusions. As I am the only nurse in the family, she made a point to tell me that she needed blood because her "hemoglobins were low.". I quickly determined that she had no idea what hemoglobin was but she was confident her transfusion therapy was necessary because her trusted family physician had told her that her "hemoglobins were low." During her admission, she signed without reading a general treatment consent that included a paragraph about blood transfusion. My grandmother was not told that there are risks associated with allogeneic transfusion nor was any alternative therapy offered. However, she believed that she was receiving appropriate medical care and she had no apparent adverse events with her hospitalization. Was my grandmother given adequate information to make an informed choice about her medical care? Did her physician and hospital meet minimum legal and ...
Most physicians typically clamp and cut the umbilical cord immediately following delivery. Some physicians advocate for delaying the clamping of the babys umbilical cord, thereby increasing the flow of blood from the placenta to the child. The practice of delayed umbilical cord clamping has been shown to improve hematocrit levels, leading to an increased number of oxygen-carrying red blood cells throughout the body.. Hematocrit levels are an important factor during surgery and blood transfusions are often required to replace blood lost during complicated procedures. This is especially true in children with critical congenital heart disease.. "Babies born with critical congenital heart disease often require multiple blood transfusions during corrective heart surgery due to the complexity of the surgery and the babies small size," said Carl Backes, Jr., MD, Neonatology fellow at Nationwide Childrens Hospital. "However, data suggests that surgical outcomes are improved when fewer blood ...
Published: 18 Jan 2017 , Last Updated: 18 Jan 2017 08:49:11 Karen Humm (Lecturer in Emergency and Critical Care) has been awarded a grant by Pet Plan for the following project: "Is Cross Matching Beneficial Prior to the First Blood Transfusion in Cats?" As veterinary practice has advanced, there has been a steady increase in the need for blood transfusions to help cats with a variety of diseases. However, identifying suitable blood donors and obtaining blood from healthy cats in a timely manner is extremely challenging. In situations when a cat has had a previous blood transfusion, it is recommended that prior to any subsequent transfusion a crossmatch screening test is performed. This is how we check that donor blood and patient blood are compatible. If no reaction is seen in this test, the donor is considered suitable and this should decrease the risk of the recipient having a reaction to the blood. A recent study of cats reported that administration of crossmatch compatible blood transfusions ...
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BACKGROUND: In sub-Saharan Africa, the prevalence of malaria parasitemia in blood donors varies from 0.6% to 50%. Although the burden of TTM in malaria-endemic countries is unknown, it is recommended that all donated blood is screened for malaria parasites. This study aimed to establish the incidence of TTM and identify a suitable screening test. METHODS: Pregnant women, children, and immunocompromised malaria-negative transfusion recipients in a teaching hospital in Ghana were recruited over the course of 1 year. Parasites detected in recipients within 14 days of the transfusion were genotyped and compared to parasites in the transfused blood. The presence of genotypically identical parasites in the recipient and the transfused blood confirmed transfusion-transmitted malaria. Four malaria screening tests were compared to assess their usefulness in the context of African blood banks. RESULTS: Of the 50 patients who received transfusions that were positive for Plasmodium falciparum by polymerase ...
Objective: To evaluate semen parameters and measure serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (T) concentrations before and 7 days after packed red cell transfusion (PCTx) in adults with sickle cell disease (SCD). Methods: This prospective study investigated 18 young adults with transfusion-dependent SCD, aged 20.7 +/- 2.88 years, with full pubertal development (Tanner's stage 5) (euogonadal), and capacity to ejaculate. Their serum ferritin levels were 1488 +/- 557ng/ml. Basal serum concentrations of FSH, LH, T and IGF-I were evaluated before and 7 days after packed red cell transfusion (PCTx). We studied the effect of PCTx on semen parameters and the endocrine functions in these 18 patients with SCD. Results: Following PCTx, a significant increase of Hb from 8.5 +/- 1.17 g/dl to 10.5 +/- 0.4 g/dl was associated with increased testosterone (12.3 +/- 1.24 nmol/L to 14.23 +/- 1.22nmol/L and gonadotropin concentrations. Total sperm count increased
Abstract:. BACKGROUND AND OBJECTIVE: This audit was conducted as a part of a quality assurance activity to assess the frequency of receiving completely filled out blood transfusion reaction forms which were accompanied by the required samples. Once this information is known, we will elevate the bar each year to achieve 100% compliance. The sub-aim was to evaluate the frequency of the reported transfusion reactions.. MATERIALS AND METHODS: The study was conducted from 1st April 2010 to 30th April 2011. The information was evaluated and the frequency of receiving completely filled blood transfusion reaction forms was assessed. The variables identified were the type of transfusion reaction, the blood component transfused, the health care personnel filling the form, and whether there was legible handwriting and a completely filled form. Transfusion reactions were reported as a percentage of the total number of units transfused.. RESULTS: During the study period, 17,880 packed red cells, 13,200 ...
This program will review the creation and benefits of Blood School, an eight-hour introductory course on transfusion safety for nurses. Recognizing that primary blood transfusion education was too procedure-centric, this course was developed as a supplement to provide education on the core foundations of transfusion medicine. Blood School uses a combination of didactic and active learning approaches, in order for the participants to feel more knowledgeable, comfortable, and safer with all transfusion-related processes. In doing so, it empowers them to be better advocates for patients, take action whenever they recognize negative situations related to blood transfusions, and help ensure that the right patient gets the right blood component for the right reason in the safest way. ...
Often transfusions are prescribed when simple and safe alternative treatments might be equally effective. As a result such a transfusion may not be necessary. An unnecessary transfusion exposes patients to the risk of infections such as HIV and hepatitis and adverse transfusion reactions.. ...
There have been previous studies with similar hypotheses and methodology. Engoren et al. 12 studied 1,915 subjects undergoing first-time isolated coronary artery bypass at St. Vincent Mercy Medical Center, Toledo, Ohio. In a Cox regression model, they demonstrated that age, New York Heart Association functional class IV, chronic obstructive pulmonary disease, peripheral vascular disease, and perioperative blood transfusion were predictors of mortality occurring between 1 and 5 yr after surgery. Detailed information about the number of units transfused was not available; therefore, quantification of transfusion was done in a limited manner, subjects were grouped according to transfusions given during the intraoperative period, postoperative period, or both. Koch et al. 13 studied 10,289 subjects undergoing isolated coronary artery surgery at the Cleveland Clinic, follow-up was 10 yr, and transfusion was quantified by the number of units of red cells transfused to subjects in the perioperative ...
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When we proceeded to go for transfusion on August 9, the doctors asked us to obtain the HIV test done. The result was positive, Sheikh told the paper. The doctors, blood bank staff and medical center superintendent said, It provides happened, what you can do? Sheikh sold his motorbike and television to pay for his daughters monthly blood transfusions and medicines.. 23 Indian kids get HIV from blood vessels transfusions AHMADABAD, India - At least 23 children suffering from a rare genetic disorder that will require regular blood transfusions possess tested positive for HIV after receiving tainted blood, officials said Monday. The children, who have problems with thalassemia and so are from poor households, all received free bloodstream transfusions at a government-run medical center in the Junagadh district of Gujarat state in western India between January and August, hospital mind G.T.. One in four people in Asia will be 60 or older by the year 2050, rising from one in 10 this year 2013, ...
I have anemia and needed a blood transfusion and attempted my first transfusion last week. After about a tablespoon of blood went into my IV, my vision grayed out and I dont remember what happened next. I was told I had chills, diaphoresis, decreased level of consciousness, eyes rolling back in head and woke up so to speak, vomiting. What happened to me? They said I had no fever but had a severe transfusion reaction. I received Benadryl and Solu-Medrol and a bag of fluid after that. They had stopped the blood when I came to and said my blood pressure had dropped to 70/40 and my pulse had dropped. My family doctor was called and diagnosed it as a vasovagal reaction. Can a severe blood transfusion reaction be called a vasovagal reaction? They said there was no hemolyzation of the blood. What exactly happened? How often does this happen? They gave me another unit with the premedication and filter, and it seemed to work okay that time. What do I need to understand about what happened ...
In one of the largest randomized controlled trials (RCTs) on GDT, the incidence of blood transfusions was double (22 vs 11%) in the GDT group patients, who received nearly twice the amount of colloids compared to the control group, even though the same transfusion threshold (Hb , 8 g/dl) was used for both groups [11]. The most feasible explanation for this clinically relevant and statistically significant difference (p = 0.04 based on a chi square test), which was not calculated nor discussed in the article [11], is that more patients in the GDT group reached Hb levels below the transfusion threshold due to hemodilution, prompting physicians to order blood transfusions. Other RCTs have also reported that patients in the GDT group, who received significantly more colloid boluses, received significantly more blood transfusions [12, 13] and had significantly higher blood loss [13] compared to the standard therapy group. In another study, the administration of more colloids led to lower Hb and DO2 ...
In our perpetually evolving pursuit to optimize the risk-benefit profile of perioperative interventions, the decision to administer allogeneic blood products is fraught with extraordinarily conflicting goals. This infographic summarizes the results of a retrospective analysis that examines the relationship between perioperative blood transfusion and infectious complications. Superficial and deep incisional infections appear not to be influenced whereas organ space infections and septic shock are associated with the administration of blood products.. CI indicates confidence interval; NSQIP, National Surgical Quality Improvement Program; OR, odds ratio; RBC, red blood cell. ...
About 100 patients aged several months to 50 years are treated in the Pediatric Hematology Unit, most of those patients receive blood transfusions monthly. The adverse reactions were routinely recorded during each transfusion. All the patients were also screened annually for the incidence of blood transmitted infections principally HIV and Hepatitis C. All those records will be systematically screened and all the immediate or late adverse reactions and complications related to blood transfusions will be summarized.. A second goal of this study will be to control the staff strictness related to the ministry of health protocol dealing to blood transfusions. ...
Question - Leukemia, on blood transfusions, swelling in the legs, myelodysplasia . Ask a Doctor about diagnosis, treatment and medication for Arthritis, Ask an Oncologist
i admit to not being very well informed about the watchtowers view on blood transfusions. i have a couple of questions that i hope someone here is able to answer.. i understand that the watchtower now considers it to be okay to receive blood fractions.. my first question is: are all fractions considered to be permissible? and if not, specifically which fractions are not permissible?.
INTRODUCTION This study evaluated the cardiovascular responses to blood transfusion in children with anemic heart failure using mostly clinical parameters. MATERIALS AND METHODS Consecutive patients with anemic heart failure presenting to a childrens emergency room and requiring blood transfusion were assessed for heart rate (HR), respiratory rate (RR), systolic blood pressure (SBP), liver size, and oxygen saturation (O 2 sat) pre-transfusion, 1-2 h into transfusion (intra-transfusion), immediate post-transfusion, and at late post-transfusion (24 h later). RESULTS A total of 75 patients were recruited of which 46 (61.3%) were males. Their mean age was 43.8 ± 40.3 months while their mean PCV at presentation was 15.0 ± 4.5%. There was a significant mean net reduction of 10 beat per minute (bpm) between the pre (139.7 ± 25.2 bpm) and intra-transfusion (129.6 ± 22.0 bpm) HR, P = 0.0004. The mean net reduction of 4 cycles/ min between the pre and intra-transfusion RR was also significant, P = 0.0033
DI-fusion, le Dépôt institutionnel numérique de lULB, est loutil de référencementde la production scientifique de lULB.Linterface de recherche DI-fusion permet de consulter les publications des chercheurs de lULB et les thèses qui y ont été défendues.
This clinic offers Pre-operative Blood Conservation Strategies for Adults.. The Blood Conservation Coordinator is located on the 3rd Floor in the Ambulatory Care area of the Carlo Fidani Building. Adults requiring surgery who are interested in avoiding blood transfusion may make an appointment directly by calling (905) 813-1100 ext. 5540. You must be having surgery at Credit Valley, or have a family doctor affiliated with Credit Valley Hospital. Alternatively, your doctor can also make the referral for you.. Many blood transfusions associated with elective surgery can be avoided through advanced planning and preparation, if there is sufficient time before surgery. Once you know that you are having surgery in the future, it may be important to ask your doctor for a blood test to determine your hemoglobin level. Generally, the higher your iron or hemoglobin level the less chance of requiring a blood transfusion during your surgical hospital stay. Not all surgeries result in a transfusion risk, so ...
A five-year-old girl in China contracted HIV through a blood transfusion, state media reported, the latest case to shine a light on an issue that has long bedevilled the country.
To study the effect of transfusion on recurrence of squamous cell carcinoma of the head and neck, we analyzed the records of 143 patients with stage 11 through N squamous cell carcinoma of the supraglottic larynx or hypopharynx for whom follow-up to recurrence or 5 years after surgical therapy was available. Variables studied were age, gender,...
VISSER, Adele et al. Blood product utilisation during massive transfusions: audit and review of the literature. SA orthop. j. [online]. 2011, vol.10, n.4, pp.25-29. ISSN 2309-8309.. Acute exsanguination is the leading cause of mortality in trauma patients.1-3 Massive blood loss potentially results in the development of the lethal triad, comprising hypothermia, acidosis and coagulopathy.4 Without prompt intervention, including the appropriate administration of blood and blood products, the majority of these patients will demise within 6 hours.2,4,5 Utilisation of blood and blood products in this setting is considered a lifesaving intervention. A massive transfusion can be defined as the 1) the infusion of five units or more of packed red cell concentrate (RCC) within 4 hours;6 2) infusion of more than ten units RCC within the first 24 hours;7-15 or 3) infusion of six or more units RCC within 12 hours.16-18 Irrespective of the formal definition, it has become evident that patients requiring six ...
... of blood components are often necessary for the patient to complete the planned cancer treatment.. Blood transfusions are appropriate for low hemoglobin (Hb) and thrombocyte transfusions for low thrombocytes (trc) which also poses a risk for serious bleeding.. ...
The practice of transfusing blood started at the bedside but over the last few decades blood transfusion has become more and more a laboratory directed…
Learn about alternatives to blood transfusion on June 24 and June 26. A new nonprofit is bringing seminars on alternatives to blood transfusions to the Peninsula. The group, Hampton Roads Health
Inspectors of National Health Service (NHS) Quality Improvement Scotland, which monitors Scottish health services, found that many health boards are not meeting the standards set in place for blood transfusions, reports The Herald. Although many NHS boards had adequate amounts of staff members specifically trained on performing blood transfusions, many hospitals did not have a system in place to ensure that only trained individuals were participating in the transfusion process, according to the Herald. Inspectors advised that hospitals ensure only trained individuals perform transfusions, as well as implementing tighter measures to identify the patient and blood correctly before the transfusion. Twelve UK patients received the wrong type of blood last year, according to the Herald. For more information, click here.
Definition of Blood transfusion reaction with photos and pictures, translations, sample usage, and additional links for more information.
HealthDay News) -- Red blood cell transfusions from young or female donors may lead to lower survival rates for recipients, according to a new Canadian study.. These results are intriguing and suggest that if you require a transfusion, your clinical outcome may be affected by the blood donors age and sex, said the studys senior author, Dr. Dean Fergusson. Hes director of the clinical epidemiology program at the Ottawa Hospital in Canada.. However, it is important to remember that our study was observational in nature, which means it cannot be considered definitive evidence, Fergusson said.. The researchers looked at blood transfusions at Ottawa Hospital between 2006 and 2013. The researchers linked more than 30,000 blood recipients with almost 81,000 donors.. The recipients health was followed for an average of just over two years.. Getting red blood cells from a woman instead of a man was linked with an 8 percent greater risk of death from any cause per unit of blood transfused, the ...
Patients undergoing general surgery operations from 2014 to 2016 were less likely to receive a blood transfusion compared with patients undergoing operations from 2011 to 2013. This reduction was demonstrated in two of the three hospitals that were included in the study, and both institutions have had specific efforts designed to reduce the need for blood transfusion in the medical and surgical populations. One of the hospitals implemented a program within the last 10 years designed to reduce the transfusion threshold throughout the medical system.10 The program involved the establishment of a 70 g/L hemoglobin transfusion threshold, education of providers and hospital staff and review and feedback of transfusion orders outside the accepted threshold. Over the four study years 2009-2012, RBC transfusions trended down despite discharges and case-mix index trending up, suggesting that the intervention may have been instrumental in reducing the transfusions within the institutions. The time periods ...
by Richard A. Nimer. Although there are references in scripture to the sacredness of blood, the Church does not hold that any scripture or revelation prohibits giving or receiving blood or blood products, such as gamma globulin, the antihemophilic factor, and antibodies through transfusion or injection, and it is therefore not opposed to its members engaging in such practices. In fact, individual wards sometimes have blood drives to increase a supply on hand when a ward member might need a transfusion. The Church, however, leaves the decision of whether to be a donor or a recipient of a blood transfusion or blood products to the individual member or family concerned.. The Church recognizes that the use of blood transfusions and blood products often saves lives by replacing blood serum volume, red and white cells, platelets, and other substances that may have been lost or damaged by disease, accident, or surgical operation. It is also aware that many operative procedures, such as open-heart ...
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Montreal, October 27, 2009 - In response to the current A(H1N1) flu pandemic, Héma-Québec has reactivated its contingency plan with the goal of continuing to efficiently provide blood components and substitutes to Québec hospitals.. Accordingly, it is important to emphasize that people who receive the A(H1N1) flu vaccine do not have to wait two days before giving blood, as is the case with other vaccines.. Moreover, individuals who have had the flu and have fully recovered may give blood.. Flu viruses-including the influenza A(H1N1) virus-cannot be spread through blood transfusions. To date, there have been no reported cases of flu infection through blood transfusion.. There is no danger of contracting a disease from donating blood, because all of the materials used for collecting blood are new, sterile, sealed and used only once. Moreover, each donated unit of blood is systematically analyzed and screened for blood-borne diseases before it is delivered to hospitals.. About Héma-Québec ...
ANN ARBOR, Mich. -- Researchers have linked womens increased likelihood of complications or death after cardiac surgery to an increased likelihood of receiving red blood cells or platelets during the
1&2 Associate Professor of Physiology, Malla Reddy Medical College for Women, Hyderabad. 3, 4 & 5MBBS Scholars. Abstract:. Background: Blood donation is a humanitarian act to save the lives of sick and needy patients. Repeated blood donation can have some adverse effects on overall health of repeated blood donors.. Objective: To evaluate cardiovascular, respiratory and lipid profiles and study the effects of repeated blood donation among repeated blood donors. To compare these parameters with persons who never donated blood.. Method: A Hospital based, comparative, cross sectional study was conducted. Twenty males, who donated blood every three months in a year were compared against 20 age matched males who never donated blood in last one year as well as they were never been the repeated blood donors before that.. Results: The weight (Wt), heart rate (HR), systolic blood pressure (SBP), respiratory rate (RR), peak expiratory flow rate (PEFR), chest expansion (CE), hemoglobin (Hb), packed cell ...
... is a medical treatment to replace blood or portions of the blood lost through injury, surgery, or disease.. During a transfusion, people normally receive only the parts of blood needed to treat their conditions. Whole blood is now rarely given as a transfusion.. Blood for transfusions may come from anonymous donors, or a person can bank his or her own blood in preparation for surgery.. ...
Feature Story Anne Paxton. Faced with unrelenting pressure to stamp out threats to the safety of the blood supply, the nations blood centers cant afford to coast on their record or let down their guard. Nevertheless, they might just be breathing a tiny sigh of relief at their recent progress in reducing cases of TRALI (transfusion-related acute lung injury), the leading cause of death from transfusion. In 2006, the AABB recommended that its members-which include most blood centers in the U.S.-adopt measures to address TRALI through plasma transfusion by November 2007, and TRALI by apheresis platelets by November 2008. The specific steps to take were left up to individual blood centers. But large numbers of them opted to move to predominantly male plasma. "In essence, using predominantly male plasma for transfusion is now the industry practice; it-or its equivalent-has become the standard of care," says James AuBuchon, MD, president and CEO of Puget Sound Blood Center, Seattle. The results have ...
Safety measures to ensure the safety of the blood supply and the selection criteria for blood donors remain unchanged. Anyone with questions about giving blood may call Donor Services at 1-800-847-2525.. Flu viruses-including the influenza A (H1N1) virus-cannot be spread through blood transfusions. To date, there have been no reported cases of flu infection through blood transfusion.. Héma-Québec would like to remind the public that blood is still needed every day and that there is no risk of contracting a disease by donating blood. All of the materials used for collecting blood are new, sterile, sealed, and used once. Furthermore, each donated unit of blood is systematically analyzed and screened for blood-borne diseases before it is delivered to hospitals.. About Héma-Québec ...
CHAGAS disease comes from a parasitic transmitted through the feces of a blood sucking insect commonly called the kissing bug. The disease is endemic in rural areas from Mexico to Argentina. An estimated one and a half two million Mexicans are affected with parasite. However, Chagas disease is spreading to other part of the world. One way is through blood transfusions. Mexicans biologist Bert Kohlmann explains: we have already got reports from Australia, Europe, the United States of America and Canada of infections through blood transfusions. Migrants from the Americas who are usually healthy give blood and nobody in those other places even thinks about screening for chagas. The world health organization estimates that in the western hemisphere, 16 to 18 million people are infected with the disease and 100 million more are at risk. At present, there is no cure for the disease [chagas], which is often fatal ...
The blood group typing market is projected to reach USD 3.12 billion by 2021 from USD 1.95 billion in 2016, at a CAGR of 9.8%.. Growth in the blood group typing market is primarily attributed to the increasing demand for blood and blood products, growing number of road accidents and trauma cases that necessitate blood transfusion, need for blood grouping during prenatal testing, and increasing usage of blood group typing in forensic sciences. Stringent regulatory standards for blood transfusion are also expected to fuel the growth of the blood group typing market during the forecast period.. The blood group typing market is segmented based on product & service, technique, test type, end user, and region. On the basis of product & service, the market is segmented into consumables, instruments, and services. The consumables segment is further categorized into antisera reagents, anti-human globulin reagents, red blood cells reagents, and blood bank saline. The consumables segment is expected to ...
Several transfusion-related complications have particular relevance to the transplant setting. Transfusions reportedly improve solid organ graft survival, especially when the donor and recipient share at least one HLA-DR antigen. Whereas the mechanism for this effect is unclear, less favorable immunomodulating effects of transfusion may increase postoperative infections and shorten survival time and disease-free intervals in patients with a variety of malignancies who are undergoing surgery. The contribution of the different components of the blood transfusion to these outcomes remains speculative. Directed donations, especially from relatives and in the setting of a recipient who is immunosuppressed, may give rise to a severe but under-appreciated immunologic consequence of transfusion: graft-versus-host disease. Although still rarely reported, transfusional graft-versus-host disease is almost invariably fatal. This complication is entirely avoidable if the transfused blood product is appropriately
A blood transfusion is when blood or parts of the blood are given to a person through an IV line placed in a vein. The blood and blood parts used for transfusion are called blood products. The blood usually comes from another person (donor). This sheet tells you more about how blood and blood products may be used to help treat cancer.
Blood transfusions are a daily routine procedure in hospitals. In a day, 16k liters of blood are transfused daily in the United States. Human being has four types of blood group- A, B, AB, O. Blood type A, B, and AB have their own antigens on their surface. Blood Antigens are basically a polysaccharide on the surface of red blood cells. Type O does not have any antigens on their surface. The demand for blood all over the world is very high, especially during emergency surgeries and operations. Blood transfusion is only possible when the blood group of donor and recipient are matched. If they are not matched, the immune cells of the recipient will attack and destroy the RBCs of the donor. Blood group O does not have an antigen on their surface, thus making them transfusable to any recipient irrespective of the blood group of the recipient. Hence, Blood group 0 are called a universal donor. However, there is a shortage of ...
... have many uses and can be critical, lifesaving procedures. Blood loss that occurs suddenly due to trauma may require an emergency transfusion to save a patients life. However, not all blood transfusion situations are related to injury. Cancer patients undergoing chemotherapy, surgical patients, pets with advanced kidney or liver disease, cats with feline
#IVTEAM #Intravenous literature: Repa, A., Mayerhofer, M., Cardona, F., Worel, N., Deindl, P., Pollak, A., Berger, A. and Haiden, N. (2013) Safety of Blood Transfusions Using 27 Gauge Neonatal PICC Lines: An in vitro Study on Hemolysis. Klinische Pädiatrie. October 24th. [epub ahead of print]. Abstract: Blood transfusions are required by the majority of extremely…
PURPOSE: A case report describing use of idarucizumab for dabigatran reversal without the use of hemostatic agents in a patient who developed acute upper gastrointestinal (GI) bleeding while receiving triple antithrombotic therapy is presented. SUMMARY: A 77-year-old man with a complex cardiac history presented to the emergency room with chief complaints of black tarry stools and low blood pressures for 4 days. His past medical history included recent percutaneous coronary intervention (PCI) and drug-eluting stent (DES) placement, atrial fibrillation, hypertension, hyperlipidemia, coronary artery disease, coronary artery bypass graft surgery, stage 3 chronic kidney disease, and cholecystectomy ...
The pre-transplantation transfusion practice over the last 20 years has been to minimize transfusions because of risks outweighing benefits. Practice may change following the recent changes in payments for the management of end-stage renal disease for Medicare patients [4, 5] and data from an AHRQ review [7, 8] suggesting that pre-transplant transfusion resulted in a neutral to beneficial effect on graft rejection, graft survival, and patient survival compared with no transfusion. Although the authors of the review acknowledged that the strength of the evidence was low. While literature on pre-transplant transfusions is abundant, the variety of patient characteristics, questions addressed, methods used, data details presented, and general study quality presents a challenge for the assessment of the effects of pre-transplant transfusions on patient outcomes. Our review aimed to address this issue through the systematic identification of high-quality studies (defined by peer review) that assessed ...
Carter spent the day yesterday in the hospital again. Not exactly how we envisioned our Saturday going, but it couldve been A LOT worse. I mentioned in the last post that Carter was close to needing a blood transfusion at our last appointment. The nurse sent his blood to get typed and stuff (I dont know what else they do...) in case we needed to come in for a transfusion later in the week. The typing etc only lasts for 3 days, so until Fri. The nurse reminded me that Friday morning was the latest I could call in order to have the transfusion in the clinic and not have to wait that extra hour for the blood tests. The doctor made it sound like he would be fine until our next appointment. So all week Carter was totally fine, running around like crazy, not needing naps.... until Friday afternoon. Of course. It just hit him so fast. He got so tired and grumpy and looked extra pale and was very sensitive, didnt want us to touch him. He asked me to carry him to bed at 5:00. He woke up at 6:30 and ...
The clinical utility of blood transfusion in anemic cardiovascular disease populations is controversial. According to the guidelines from the American College of Physicians and the American Society of Anesthesiology, the "transfusion threshold" for patients without known risk factors for cardiac disease is a hemoglobin level in the range of 6 to 8 g/dL.55 In 78 974 elderly patients hospitalized with acute myocardial infarction, blood transfusion was associated with a significantly lower 30-day mortality rate among patients with a hematocrit ≤30% on admission.56 In 838 critically ill patients (26% with cardiovascular disease), maintaining hemoglobin at 10 to 12 g/dL did not provide additional benefits on 30-day mortality compared with maintaining hemoglobin at 7 to 9 g/dL.57 Blood transfusion may be associated with other adverse effects including immunosuppression with increased risk of infection, sensitization to HLA antigens, and iron overload.58,59 Given this profile of risks and benefits, ...
Based on the study of the UK HTA Unit found no controlled trial to evaluate the importance of hemoglobin or blood counts. All the available scientific evidence in the form of case-series. Preoperative routine examination showed Hb levels ,10 to 10.5 g / dl at 5% patients, rarely with Hb ,9 g / dl, and the only change management in the 0.1 to 2.7% of patients. Assessment of scientific evidence does not support the policy of Hb examination or routine blood counts at all patients and vice versa there is no scientific evidence that states that examination of the harm. Conventional limit of anemia is Hb ,10 g / dl, when less than the value of the operation can be postponed. But there is some scientific evidence that the risk of not operating increased significantly up to a Hb 8 g / dl. In healthy individuals, Blood transfusions are usually required if Hb ,7 g / dl. But not so clear whether the transfusion of red blood effect when Hb between 7 and 10 g / dl. A multi-center study recently showed no ...
The US Department of Defense recently made the decision to open direct ground combat roles to women. Blood product transfusion is an essential component of the US Military guidelines for tactical combat casualty care and damage control resuscitation, but blood transfusion carries with it the specific side effect of alloimmunization-a uniquely significant side effect for young women who may desire subsequent pregnancies. Presently to be considered are the changes that may need to be made to blood transfusion in the setting of battlefield medicine to optimally care for combat-injured women, as a majority of the existing data regarding the risks of transfusion in the trauma setting involve predominantly men ...
BALTIMORE, Md., USA: Blood transfusion has wide variation in frequency by surgical procedure and physician, as well as wide variation in the hemoglobin trigger used to help decide whether to transfuse, researchers have found. Their study also found that a significant number of transfusion decisions are made without laboratory hemoglobin measurements.
Chronic post-hemorrhagic anemia. The best method of treatment is to remove the source of blood loss (excision of hemorrhoidal where to buy modafinil reddit nodes, resection of the stomach for bleeding ulcers, etc.). However, a radical cure of the underlying disease is not always possible (for example, in inoperable gastric cancer). As a buy modafinil reddit where to buy modafinil reddit replacement therapy and stimulation of erythropoiesis, it is necessary to produce repeated blood transfusions in the form of red blood cell transfusions. Transfusion of what is modafinil prescribed for medium doses (200-250 ml of whole blood or 125 modafinil prescription - 150 ml of red blood cells with an interval of 5-6 days) is recommended.. The appointment of iron supplements is very important. Iron preparations are administered orally and parenterally. During the period of treatment it is necessary to limit the intake of fats, milk, flour products, as they are where to buy modafinil reduce the absorption of ...
BLOOD & BLOOD TRANSFUSIONS DR.SHALINI SINGH (PG) BLOOD blood and blood transfusions 2 OBJECTIVES Properties and functions of blood Plasma proteins Bone marrow
Wondering if a blood transfusion during pregnancy is right for you? This article covers the side effects of blood transfusions during pregnancy.
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867623/. "There is a much higher suicide rate among mixed race children - they are five times more likely to commit suicide than someone of a singular race.. Hybridization shatters the form entirely into separate units of characteristics, and these units get jumbled up again each time they get passed on. People see attractive half-castes and think that the children will inherit the same characteristics, but it is impossible for them to be passed on like that, as they separate out again into the individual races features ensuring there is no unity of form to be passed on. Since Black genes are dominant and White genes are recessive, Mulattoes will always look more Black than White.. Blood transfusions are not possible between the races (yet they are possible between cats and dogs) and neither are bone marrow transplants. A mixed race person stands little chance of finding a donated organ that will not reject their mismatched body, since the organs ...
Annual Sympoisum Transfusion Medicine of the Dutch Blood Transfusion Society (NVB) and TRIP (Transfusion and Transplantation Reactions in Patients) will take place on 25-26 May 2016.
Blood transfusions are inherently dangerous (Table 3.10). In addition to the frequent non-hemolytic reactions, ABO incompatibility threatens the poten
en] BACKGROUND: Numerous articles describe the reduction of perioperative bleeding by the therapeutic or prophylactic administration of drugs such as prostacyclin, desmopressin, and natural or synthetic antifibrinolytics. METHODS: A review of the literature was carried out to help the reader define the indications of these drugs during cardiopulmonary bypass operations, highlight the questions that remain concerning their indications and modes of action, and suggest future studies to answer these remaining questions. RESULTS: Prostacyclin reduces platelet trauma induced by extracorporeal circulation but does not effectively reduce postoperative bleeding and transfusion requirements. Desmopressin acts as a glue, improving platelet adhesion, and may be effective when postoperative bleeding is excessive, but its routine use in cardiac operations cannot be recommended. Natural and synthetic antifibrinolytics inhibit plasmin and plasmin-induced platelet dysfunction. These agents have been shown to ...
One of the first clues to the cause of the AIDS epidemic was the mode of transmission. People who acquired AIDS were exposed to blood and body fluids of others with the disease. Hemophiliacs received multiple blood transfusions. Though the blood they received was filtered, they became ill. Viruses (and only viruses) were able to pass through these filters. Also, hemophiliacs were a more diverse group of people, without the other putative exposures of male homosexuals and IV drug users. This led epidemiologists and researchers to consider a virus as being the ultimate cause of AIDS, and not some combination of drugs, sexual practices, and co-infections. Another clue came from cell biology. The primary cell-type destroyed in AIDS is the CD4+ lymphocyte. There had been recent discoveries that retroviruses could infect CD4+ lymphocytes.[19] In fact a model existed in HTLV-1, a virus that is blood borne and infects CD4+ cells. HTLV was one of the first viruses thought to cause AIDS. Once HIV was ...
One of the first clues to the cause of the AIDS epidemic was the mode of transmission. People who acquired AIDS were exposed to blood and body fluids of others with the disease. Hemophiliacs received multiple blood transfusions. Though the blood they received was filtered, they became ill. Viruses (and only viruses) were able to pass through these filters. Also, hemophiliacs were a more diverse group of people, without the other putative exposures of male homosexuals and IV drug users. This led epidemiologists and researchers to consider a virus as being the ultimate cause of AIDS, and not some combination of drugs, sexual practices, and co-infections. Another clue came from cell biology. The primary cell-type destroyed in AIDS is the CD4+ lymphocyte. There had been recent discoveries that retroviruses could infect CD4+ lymphocytes.[19] In fact a model existed in HTLV-1, a virus that is blood borne and infects CD4+ cells. HTLV was one of the first viruses thought to cause AIDS. Once HIV was ...
Iron overload (IO) because of multiple blood transfusion as a definite therapy for hematological disease with chronic and severe anemia has become a major concern. Deleterious complication contributed by chemically reactive deregulated iron may affect cellular homeostasis systemically lead to tissue and organ damage. When this toxicity occurred in blood cells, alteration of peripheral hematological profile concerning erythrocyte, leucocyte, and platelet most likely to be modified and imperatively need to be evidenced. Theexperimental IO mice model was established by injecting a low and high dose of iron dextran intraperitoneally. Peripheral erythrocyte, leucocyte and platelet indices measured by hematology analyzer were analyzed. A dynamic tendency of leucocyte absolute cell number and differential cell count of low and high dose iron treatment and a significant decrease of differential monocyte count were found. In addition, high dose iron treatment showed a significantly lower mean platelet ...
Iron overload (IO) because of multiple blood transfusion as a definite therapy for hematological disease with chronic and severe anemia has become a major concern. Deleterious complication contributed by chemically reactive deregulated iron may affect cellular homeostasis systemically lead to tissue and organ damage. When this toxicity occurred in blood cells, alteration of peripheral hematological profile concerning erythrocyte, leucocyte, and platelet most likely to be modified and imperatively need to be evidenced. Theexperimental IO mice model was established by injecting a low and high dose of iron dextran intraperitoneally. Peripheral erythrocyte, leucocyte and platelet indices measured by hematology analyzer were analyzed. A dynamic tendency of leucocyte absolute cell number and differential cell count of low and high dose iron treatment and a significant decrease of differential monocyte count were found. In addition, high dose iron treatment showed a significantly lower mean platelet ...
Mediwares Bloodsafe Tx mobile device integrates with e-medical record systems and ensures that patients receive correct blood transfusions.
IMHA is an autommune disease wherein the body attacks its own red blood cells. The dog very quickly develops a low red blood cell count (anemia) that often requires multiple blood transfusions to correct, if at all. This condition may also predispose dogs to forming blood clots, predominantly in the lungs or brain. Treatment requires hospitalization, drugs that suppress the immune system, and often blood thinners. There have been cases where a dog does well with minimal treatment, however for the overwhelming majority the disease is unfortunately fatal. ...
Over the last several decades, the University of Rochester has led the way in research about the risks and benefits of blood transfusions. A blood transfusion should be thought of as a liquid organ transplant, and the decision to transfuse should include careful assessment of the potential risks versus the expected benefits. There is strong scientific evidence that overall, patients who avoid transfusions have fewer complications, faster recoveries, and shorter hospital stays.. ...
M1.MC.79) A 55-year-old male presents to his primary care doctor with several weeks of headaches and low-grade fevers. His medical history is notable for a motor vehicle accident when he was in his 20s that required multiple blood transfusions, and three separate courses of antibiotics for pneumonia in the past 2 years. Review of systems reveals 10-pound weight loss in last 3 months. He has notable left-sided weakness while walking into the clinic, and, on further exam, he has markedly slurred speech and cervical, axial, and inguinal lymphadenopathy is present. A head CT is ordered, which is shown in Figure A. What is the most likely diagnosis? ...
Blood transfusion is a common intervention in the hospital setting, and its benefits may not be clear but it has associated risks. Despite this, transfusion consent may not be obtained satisfactorily. We assessed transfusion consent effectiveness by
Care guide for Blood Transfusion Reactions. Includes: possible causes, signs and symptoms, standard treatment options and means of care and support.
To support our Vision of a Total Healing Environment, Yavapai Regional Medical Center (YRMC) wants you to be informed about your healthcare. We also want to partner with you to help you make decisions about the care you receive. This includes presenting you with treatment options and helping you understand the availability of alternatives to blood transfusions.. Blood transfusions have been an important life-saving therapy for many years. What is frequently overlooked, however, is the fact that a therapy deemed suitable yesterday may no longer be the first choice today. While blood transfusions continue to be important to healthcare delivery, growing evidence shows that patients who do not receive a transfusion have lower infection rates as well as fewer kidney, lung and heart complications. This is the science behind Patient Blood Management (PBM) and the reason why YRMC has made the commitment to adopt comprehensive PBM protocols for patients who prefer to not receive a transfusion. ...
To the editor: We are concerned that recommendations in the Brief Report "Anti-A Hemolytic Transfusion with Packed O Cells" (1) in the October 1978 issue do not represent a practical approach to the clinical problem that is described. Having observed the "very rare event" of a nonanaphylactic hemolytic episode in a type A1 recipient of a unit of type O Red Blood Cells ("packed" cells), Dr. Inwood and Mr. Zuliani recommend that clinicians "rigidly accept the principle that only ABO homologous blood should be transfused to patients." Alternatively, the authors recommend that if circumstances demand, "either the group O cells ...
9781444319583 Our cheapest price for Alternatives to Blood Transfusion in Transfusion Medicine is $172.80. Free shipping on all orders over $35.00.
Safe Blood Sampling for Transfusion is an adjunct to the Sampling Unit in the Safe Transfusion Practice course and offers an alternative method of engaging users through video based learning. It highlights the high risk or error hotspots when taking a blood sample for transfusion (identifying the patient, labelling the sample tube, matching the blood sample with the request form) and explains the procedure which must be followed correctly or the consequences for the patient could be fatal. This course is aimed at doctors, nurses, midwives, phlebotomists and other clinical staff who take blood samples for pre-transfusion testing.. Sessions:. ...
Substantial variability in practice exists in clinical transfusion, patient blood management and blood conservation in paediatrics. Neonates and children are frequently transfused patient populations, yet they are relatively under-represented in clinical trials and the evidence-base to guide practice is limited. A number of clinical practices are extrapolated from the results of adult studies. Yet neonates and children have unique pathophysiology, specific vulnerabilities and different risk profiles compared to adult transfusion recipients. Transfusion decision making in paediatrics needs do consider the potential risks and benefits of a transfusion and any alternatives to transfusion. ...
If you have repeated blood transfusions, its possible for your body to get too much iron. This can damage your heart and other organs. Make sure to avoid vitamins that contain iron, and dont take extra vitamin C, which can increase how much iron you absorb from food. If you have too much iron, your doctor may give you chelation therapy. This is a medicine that helps remove iron from your body.. Less common treatments for severe thalassemia include:. ...
Learn more about Blood Transfusion at Memorial Hospital DefinitionReasons for ProcedurePossible ComplicationsWhat to ExpectCall Your Doctorrevision ...
Learn more about Blood Transfusion at Parkland Medical Center DefinitionReasons for ProcedurePossible ComplicationsWhat to ExpectCall Your Doctorrevision ...
LOBO, Suzana Margareth et al. Transfusion practices in brazilian Intensive Care Units (pelo FUNDO-AMIB). Rev. bras. ter. intensiva [online]. 2006, vol.18, n.3, pp.234-241. ISSN 0103-507X. http://dx.doi.org/10.1590/S0103-507X2006000300004.. BACKGROUND AND OBJECTIVES: Anemia of critical illness is a multifactorial condition caused by blood loss, frequent phlebotomies and inadequate production of red blood cells (RBC). Controversy surrounds the most appropriate hemoglobin concentration "trigger" for transfusion of RBC. We aimed to evaluate transfusion practices in Brazilian ICUs. METHODS: A prospective study throughout a 2-week period in 19 Brazilian ICUs. Hemoglobin (Hb) level, transfusion rate, organ dysfunction assessment and 28-day mortality were evaluated. Primary indication for transfusion and pretransfusion hemoglobin level were collected for each transfusion. RESULTS: Two hundred thirty-one patients with an ICU length of stay longer than 48h were included. An Hb level lower than 10 g/dL was ...
Management of the critically bleeding patient can be encountered in many medical and surgical settings. Common for these patients is a high risk of dying from exsanguination secondary to developing co
Cell Therapy or Cytotherapy in which administration of living cell in individual for the treatment of a disease. Cell therapy is a technology that relies on replacing diseased cells with healthy ones. The cells can be taken from same individual or another individual, stem cells such as bone marrow or induced pluripotent stem cells, skin fibroblasts or adipocytes. Some form of Cell Therapy are Whole blood transfusions, packed red cell transfusions, platelet transfusions, bone marrow transplants, and organ transplants.. Gene therapy is the Therapeutic delivery of nucleic acid into a patients cells as a drug to modify the expression of an individual genes or repair abnormal genes. Gene therapy uses DNA that encodes a therapeutic, functional gene to replace a mutated gene. The polymer molecule is packaged within a vector and it act as a special carrier.. ...
The UNM cause of death also does not account for the multiple transfusions of blood products she was given at the UNM hospital.. These symptoms do not make sense in light of a random blood clot in the lungs. However, they do make sense in light of the clotting and hemorrhaging that exemplifies DIC. It more likely that during Atkins four-day abortion process - during which she retained the body of her dead baby - a bacterial infection turned septic and initiated a fatal cascade of symptoms associated with Disseminated Intravascular Coagulation.. It is Operation Rescues opinion, based the facts found in the autopsy report, that the UNM cause of death determination is simply not the truth.. The abortion facilities involved in patient deaths first try to conceal the fact that a patient died. If that doesnt work, the abortion businesses immediately attempt to deny any culpability for their patients death. What is the easiest way to do that? Whitewash the truth by blaming the woman and/or her ...
Buy and download royalty-free image ID 4571769: Blood transfusion abstract allegory concept. Transfusion juice from orange to mandarin. Isolated on white. ..
Iron concentration in serum increases in cases of pernicious, aplastic or hemolytic anemia, hemocromatosis, acute leukemia, molybdosis, acute hepatitis, lack of vitamin B6, thalassemia, high Fe intake during treatment, repeated blood transfusions, acute Fe poisoning, nephritis ...
Blessings to all of you and your search for healing. Please suspect immune dys regulation and inflammation as a root cause of so many symptoms when the doctors say there is nothing wrong we can find and its all in your head. Take that as a good sign that you can recover before the disease state as a result of immune hormonal imbalances. Even after a disease state, once the imbalance is corrected the disease can go away. Again my "condition" was life threatening and was prepared to die in the hospital every time due to platelets below 5000. That is how severe immune hormonal imbalances can get. I recommend the book: The Balance Within. Google it on amazon. It is a life saver.. ...
Transfusion-Related Acute Lung Injury (TRALI) is an important life-threatening complication that is related with blood transfusion. The frequency is reported as 1/5.000. It is generally characterized with hypoxia that appears at the 2-6th hours after the blood transfusion, bilateral infiltration in the chest radiography, and non-cardiogenic pulmonary edema. Acute respiratory distress, hypotension, tachycardia and fever accompany the clinical picture. Past surgery, blood transfusion, and sepsis are among the factors that trigger the disease. In this study, the efficiency of the hemodialysis applied in the right time in the treatment of a heavy TRALI case developed after a blood transfusion has been presented.. Keywords: Acute lung injury, efficiency, hemodialysis, ...
OHerlihy Access Consultancy (OHAC) was engaged by the Irish Blood Transfusion Service to carry out an access audit of the National Blood Centre at St Jamess Hospital and the Irish Blood Transfusion Service Blood Donor Clinic on DOlier Street, Dublin 2.. As part of the service OHAC liaised with the organisations Access Officer, carried out an access audit of the buildings, prepared a report of the findings and presented the findings to the Irish Blood Transfusion Service.. Work on this project ran from October 2008 to August 2009.. ...
Abstract Bilateral total knee arthroplasty (BTKA) patients may require blood transfusion which has its risks. Anti-fibrinolytic drugs such as aprotinin, aminocaproic acid and tranexamic acid (TXA) have reduced transfusion requirements in major surgery. This retrospective audit was performed to assess effectiveness of TXA in reducing blood transfusion rate in single-stage sequential BTKA cases operated by a single surgeon. Records of 91 patients given TXA and 80 controls who were operated before 2012 and not given TXA were reviewed. TXA was given 15mg/kg intravenously (IV) before tourniquet deflation and 3 hours postoperatively.Blood transfusion was done in 9(10%) patients in the TXA group compared to 20(25%)in the control group (p|0.01). One (1.25%) patient in the control group had non-fatal pulmonary embolism.TXA appeared to be effective in decreasing post-operative blood loss and requirement for blood transfusion after single-stage BTKA.
The NIBTS exists to fully supply the needs of all hospitals and clinical units in the province with safe and effective blood and blood products and other related services. The discharge of this function includes a commitment to the care and welfare of our voluntary donors.. The Northern Ireland Blood Transfusion Service, established in 1946, is an independent, Special Agency of the DHSSPS. It is responsible for the collection, testing and distribution of over 64,000 blood donations each year. The Service operates three mobile units at around 250 locations throughout the province. Including headquarters, located on the site of the Belfast City Hospital, a total of almost 1,000 donation sessions are held each year.. ...
A Quebec coroner has found the refusal to accept blood transfusions played a key role in the deaths of two Jehovahs Witnesses who died of childbirth complications last year.
Background Platelet transfusions are used in modern clinical practice to prevent and treat bleeding in people who are thrombocytopenic due to bone marrow failure. Although considerable advances have been made in platelet transfusion therapy in the last 40 years, some areas continue to provoke debate, especially concerning the use of prophylactic platelet transfusions for the prevention of thrombocytopenic bleeding. This is an update of a Cochrane review first published in 2004, and previously updated in 2012 that addressed four separate questions: prophylactic versus therapeutic-only platelet transfusion policy; prophylactic platelet transfusion threshold; prophylactic platelet transfusion dose; and platelet transfusions compared to alternative treatments. This review has now been split into four smaller reviews looking at these questions individually; this review compares prophylactic platelet transfusion thresholds. Objectives To determine whether different platelet transfusion thresholds for
The article by Sniecinski et al. (1) on the treatment of two Jehovahs Witnesses with coagulopathy presents a laudable approach toward improved communication with patients who may offer a rather unique medical challenge. Three aspects of this paper merit comment.. First, the paper highlights how far we have come in the past few decades in the treatment of Jehovahs Witnesses. Notice, for example, that the postoperative hematocrit in these two patients were 23% and 20% respectively, and that both patients had "good outcomes." Actually, this is not unusual in the reports on patients who are Jehovahs Witnesses. Yet, it was not that long ago that some physicians generally applied the "10/30" rule as a transfusion trigger. We have learned much about alternatives for treating anemia and now coagulopathy, as this paper shows.. Second, the authors commendably capture the issue here that the decision on whether to receive these processed blood fractions was up to the two patients. This is not, though, ...
A 10-year-old male child came to our out-patient department (OPD) for evaluation of refractory anemia. He had received adequate dietary and oral iron supplementation but still required multiple blood transfusions. He had no anorexia, nausea, vomiting, diarrhea, abdominal cramps or bleeding from any site. There was no family history of blood transfusions. Laboratory investigations showed hemoglobin of 6.4 gm/dl, total leucocyte count 7600 cells/cumm, erythrocyte sedimentation rate (ESR) 18 mm/hr at end of 1 hour, packed cell volume 22%, mean corpuscular volume 54.1fL, mean corpuscular hemoglobin concentration (MCHC) 25.4gm/dL, Red blood cell distribution width (RDW) 17.2%, reticulocyte count 1.13%, serum ferritin 2.6ng/dL, serum iron 15ug/dL and Total Iron Binding Capacity (TIBC) 570 mcg/dL suggestive of iron deficiency anemia (IDA). Peripheral film showed microcytic hypochromic anemia. Hemoglobin electrophoresis and thyroid function tests were normal. Routine stool examination was normal and ...
Today, more than 100 Jehovahs Witnesses in wool coats and soggy boots gathered silently outside the courtroom doors. Many said they were prepared to wait as long as it takes for the judge to reach a resolution, even weeks.. We cherish our truth, said Lena Sijanova, 27, who joined the Jehovahs Witnesses with her mother, and they are trying to take it away. But you cannot forbid peoples right to their faith because that right comes only from God.. According to the complaint filed by a Moscow district prosecutor, the Jehovahs Witnesses have violated the 1997 law by preaching religious discrimination, breaking up families, withholding medical treatment -- all in the name of their one true religion. After an exhaustive textual analysis of literature disseminated by the Witnesses door-to-door proselytizers, the prosecutors concluded that overseers in Russia and abroad not only control the spiritual environment of the congregation, but also subject the manner of life, thinking, ...

Refusal of blood transfusions by Jehovahs Witnesses not always detrimental, research finds - National Secular SocietyRefusal of blood transfusions by Jehovah's Witnesses not always detrimental, research finds - National Secular Society

While many patients do not have blood transfusions during and after heart surgery, they also do not undergo the same blood ... All Jehovahs Witness patients refused blood transfusions. In the other group, 38,467 did not receive transfusions while 48,986 ... Refusal of blood transfusions by Jehovahs Witnesses not always detrimental, research finds. Posted: Fri, 06 Jul 2012 15:44 ... Home » News » Refusal of blood transfusions by Jehovahs Witnesses not always detrimental, research finds ...
more infohttp://www.secularism.org.uk/news/2012/07/refusal-of-blood-transfusions-by-jehovahs-witnesses-not-always-detrimental-research-finds

Jehovahs Witnesses - Blood Transfusions - Warfield Boulevard church of ChristJehovah's Witnesses - Blood Transfusions - Warfield Boulevard church of Christ

A transfusion of blood is not eating or drinking blood. Blood transfusions and intravenous feeding are not even the same. A ... Intravenous feeding is supplying food, not blood, to one who cannot eat normally. A transfusion of blood from one person to ... from blood equals taking blood into the body by transfusion. The argument is based on a bad analogy. They equate "abstaining ... "I have had no blood transfusions." That passage has absolutely nothing to do with transfusions. ...
more infohttp://wbcoc.org/index.php/2010/04/11/blood-transfusions/

How to Become one of Jehovahs Witnesses: 9 Steps (with Pictures)How to Become one of Jehovah's Witnesses: 9 Steps (with Pictures)

As one of Jehovahs Witnesses you will be expected to refuse medical treatment involving blood transfusions of whole blood, red ... Blood fractions and several procedures involving blood such as hemodilution, plasmapheresis, blood salvage, heart-lung machine ... die each year as a result of refusing blood transfusions. Jehovahs Witnesses have said such statements are a "myth" and are " ... "keep abstaining from things sacrificed to idols and from blood." Some have claimed many Witnesses, including children, ...
more infohttps://www.wikihow.com/Become-one-of-Jehovah%27s-Witnesses

The Effects of Hemoglobin-Based Oxygen Carriers On Mean Arterial Press by Veronique C. Hionis"The Effects of Hemoglobin-Based Oxygen Carriers On Mean Arterial Press" by Veronique C. Hionis

Nevertheless, the century-old quest for a suitable blood substitute persists. The elimination of unwanted side effects, ... especially transfusion-transmitted diseases, the problems and high cost factor involved in collecting and storing human blood, ... and the need for compatibility testing are the driving forces contributing towards the development of blood substitutes. The ... In the US today, blood transfusion is safer than ever. Nevertheless, the century-old quest for a suitable blood substitute ...
more infohttps://scholarscompass.vcu.edu/etd/1467/

UI Team Receives Funding For Neonatal Anemia ResearchUI Team Receives Funding For Neonatal Anemia Research

... aim to refine traditional red blood cell transfusion treatment and assess the efficacy of transfusion and non-transfusion ... The goal is to reduce the number of transfusions given to premature infants and to determine the best transfusion product to ... the problem is severe enough to require a blood transfusion.. In addition to investigating the underlying mechanisms of ... use when transfusions are necessary.. Widness and Mock will study red blood cell survival in the circulation. Veng-Pedersen ...
more infohttp://news-releases.uiowa.edu/2006/september/092106anemia.html

ABO blood group systemABO blood group system

What is ABO blood group system? ABO blood group system meaning. ABO blood group system sense. ABO blood group system FAQ. ABO ... ABO blood group system definition. Explain ABO blood group system. ... ABO blood group system Definition. *(n) a classification system for the antigens of human blood; used in blood transfusion ... ABO blood group system. English Dictionary -> Letter A -> ABO blood group system. Search Dictionary: ...
more infohttp://www.wordthrill.com/define/ABO+blood+group+system/

American Red Cross | International DoveAmerican Red Cross | International Dove

I am a Red Cross blood donor and I wont be tired to donate blood. I started donating blood when I was nineteen years old while ... HIV and HCV test detects the generic material of transfusion-transmitted virus e.g. HIV without waiting for the body to form ... Because of my blood type, I usually do a double donation. I feel good when donating blood since I am able to save peoples ... Blood donation. A large percentage of donated blood is supplied by the American Red Cross in United States which is then sold ...
more infohttp://internationaldove.com/american-red-cross/

Blood Transfusion | Blood Donation | MedlinePlusBlood Transfusion | Blood Donation | MedlinePlus

Get information on blood donation, the blood donation process, and blood transfusion. ... To keep blood safe, blood banks carefully screen donated blood. The risk of catching a virus from a blood transfusion is low. ... Sometimes it is possible to have a transfusion of your own blood. During surgery, you may need a blood transfusion because of ... Blood donation before surgery (Medical Encyclopedia) Also in Spanish * Blood transfusions (Medical Encyclopedia) Also in ...
more infohttps://medlineplus.gov/bloodtransfusionanddonation.html

Zika and Blood Transfusion | Zika virus | CDCZika and Blood Transfusion | Zika virus | CDC

... territories screen donated whole blood and blood components with a blood screening nucleic acid test licensed for use by FDA. ... Zika Virus Blood Screening. *Blood donor screening on the basis of a questionnaire, without a laboratory test, is insufficient ... For Blood Collection Centers and Health Departments. One of the most important aspects of blood safety is making sure donated ... Blood donations that test positive for Zika virus are removed from the blood supply. ...
more infohttps://www.cdc.gov/zika/transmission/blood-transfusion.html

What Is a Blood Transfusion? Risks, Procedure, Side EffectsWhat Is a Blood Transfusion? Risks, Procedure, Side Effects

Blood transfusion reactions, side effects, risks, and complications include allergic reactions, infections, and lung injuries. ... The type of blood transfusion depends on the situation. ... routine procedure used for blood loss from severe injuries or ... To keep blood safe, blood banks carefully screen donated blood.. The risk of catching a virus from a blood transfusion is very ... The type of blood transfusion you need depends on your situation.. Red Blood Cell Transfusions. Red blood cells are the most ...
more infohttps://www.medicinenet.com/blood_transfusion/article.htm

WHO with support from Government of Japan strengthens blood transfusion services for safe, sustainable and quality blood in...WHO with support from Government of Japan strengthens blood transfusion services for safe, sustainable and quality blood in...

Blood transfusion is one of the therapeutic procedures performed during hospitalizations and undoubtedly helps patients who are ... injured, having surgery, receiving treatments or are being treated for diseases that affect the blood. ... Technical Officer for Blood Transfusion Safety.. "Blood transfusion safety is a critical intervention in the national health ... Juba, 1 December 2017: Every second, someone in the world needs blood. Blood transfusion is one of the therapeutic procedures ...
more infohttp://www.afro.who.int/news/who-support-government-japan-strengthens-blood-transfusion-services-safe-sustainable-and

Blood transfusion - WikipediaBlood transfusion - Wikipedia

Blood donation[edit]. Main article: Blood donation. Blood transfusions use as sources of blood either ones own (autologous ... Blood transfusion is the process of transferring blood or blood products into ones circulation intravenously.[1] Transfusions ... Red cell transfusion[edit]. Main article: Packed red blood cells. Historically, red blood cell transfusion was considered when ... Transfusion Evidence Library searchable source of evidence for transfusion medicine.. Blood Transfusion Societies[edit]. * ...
more infohttps://en.wikipedia.org/wiki/Blood_transfusion

Blood transfusion - NHSBlood transfusion - NHS

A blood transfusion is when youre given blood from someone else (a donor). Its a very safe procedure that can be life-saving. ... Blood transfusion A blood transfusion is when youre given blood from someone else (a donor). Its a very safe procedure that ... A blood transfusion can replace blood youve lost, or just replace the liquid or cells found in blood (such as red blood cells ... These can reduce your chances of needing a blood transfusion.. Giving blood afterwards. Currently, you cant give blood if ...
more infohttps://www.nhs.uk/conditions/blood-transfusion/

Blood TransfusionsBlood Transfusions

A blood transfusion is a safe and relatively simple medical procedure that replaces blood lost during surgery or because of an ... Why Blood Transfusions Are Performed. The three main reasons why a child may need a blood transfusion are:. *Loss of blood ... A blood transfusion can make up for a loss of blood or any part of the blood. Although whole blood can be transfused, it is ... These markers determine if someone has type A blood, type B blood, type O blood, or type AB blood. Each blood type also can be ...
more infohttp://kidshealth.org/en/parents/blood-transfusion.html?WT.ac=ctg

Blood TransfusionsBlood Transfusions

A blood transfusion is a safe and relatively simple medical procedure that replaces blood lost during surgery or because of an ... Why Blood Transfusions Are Performed. The three main reasons why a child may need a blood transfusion are:. *Loss of blood ... A blood transfusion can make up for a loss of blood or any part of the blood. Although whole blood can be transfused, it is ... These markers determine if someone has type A blood, type B blood, type O blood, or type AB blood. Each blood type also can be ...
more infohttp://kidshealth.org/ChildrensHealthNetwork/en/parents/blood-transfusion.html

Re: blood transfusionRe: blood transfusion

... Caroline Kaufmann. * *RE: blood transfusion Heikkinen, Megan B. * *RE: blood transfusion Caroline ... RE: blood transfusion Caroline Kaufmann. * *Re: blood transfusion Belinda. * * ... Re: blood transfusion Lance Mon, 15 Oct 2007 09:40:35 -0700 ... blood transfusion Angela B.. * *Re: blood transfusion Lance. * ...
more infohttps://www.mail-archive.com/[email protected]/msg33263.html

Blood transfusion coverageBlood transfusion coverage

... blood pint cost coverage differences between Part A & Part B. Learn more. ... Is blood transfusion coverage part of Medicare policy? Hematology & ... Have the blood donated. Part B:. Your provider may get blood from a blood bank at no charge. In that case, for every unit of ... covers blood you get as a hospital inpatient. Medicare Part B (Medical Insurance) covers blood you get as a hospital outpatient ...
more infohttps://www.medicare.gov/coverage/blood

Blood transfusion | NICEBlood transfusion | NICE

Blood transfusion. Number. NG24. Date issued. November 2015. Other details. Is this a recommendation for the use of a ... Red blood cell transfusion thresholds for patients with chronic cardiovascular disease:- What is the clinical and cost ... Why this is important:- The literature suggests that there may be some evidence of harm with the use of restrictive red blood ... but further studies are needed to determine the optimal transfusion threshold for patients with chronic cardiovascular disease. ...
more infohttps://www.nice.org.uk/about/what-we-do/research-and-development/research-recommendations/ng24/1

Blood transfusion | NICEBlood transfusion | NICE

Blood transfusion. Number. NG24. Date issued. November 2015. Other details. Is this a recommendation for the use of a ... Fresh frozen plasma transfusions may cause adverse outcomes in people who are critically ill, including transfusion-related ... This study showed that a high proportion of fresh frozen plasma transfusions had unproven clinical benefit.. Better evidence ... acute lung injury, transfusion-related circulatory overload, multi-organ failure and an increased risk of infections.. A ...
more infohttps://www.nice.org.uk/about/what-we-do/research-and-development/research-recommendations/ng24/4

WHO | 10 facts on blood transfusionWHO | 10 facts on blood transfusion

An unnecessary transfusion exposes patients to the risk of infections such as HIV and hepatitis and adverse transfusion ... Unnecessary transfusions expose patients to needless risk. Often transfusions are prescribed when simple and safe alternative ... As a result such a transfusion may not be necessary. ...
more infohttp://who.int/features/factfiles/blood_transfusion/blood_transfusion/en/index9.html

Blood transfusion - Drugs.comBlood transfusion - Drugs.com

It also can help if an illness prevents your body from making blood correctly. ... A blood transfusion can help replace blood lost due to surgery or injury. ... Your blood will be tested before a transfusion to determine whether your blood type is A, B, AB or O and whether your blood is ... A blood transfusion also can help if an illness prevents your body from making blood or some of your bloods components ...
more infohttps://www.drugs.com/mcp/blood-transfusion

Blood transfusion medicine | The BMJBlood transfusion medicine | The BMJ

In the past few years there has been increasing concern about blood transfusion safety. Avoidable transfusion errors, mostly in ... Risks of red blood cell transfusion (adapted from British Committee for Standards in Haematology (2001)1) ... Finally it emphasises the need for careful education and training of all those involved in blood prescribing and blood ... Concerted efforts must now be made to reduce inappropriate blood use and to use alternatives and blood sparing agents ...
more infohttps://www.bmj.com/content/325/7356/143

Autologous blood transfusion | The BMJAutologous blood transfusion | The BMJ

Autologous blood transfusion Br Med J (Clin Res Ed) 1987; 294 :442 ... Autologous blood transfusion. Br Med J (Clin Res Ed) 1987; 294 doi: https://doi.org/10.1136/bmj.294.6569.442 (Published 14 ...
more infohttp://www.bmj.com/content/294/6569/442.1

Blood TransfusionBlood Transfusion

... is a medical treatment to replace blood or portions of the blood lost through injury, ... Whole blood is now rarely given as a transfusion.. Blood for transfusions may come from anonymous donors, or a person can bank ... During a transfusion, people normally receive only the parts of blood needed to treat their conditions. ...
more infohttps://www.rexhealth.com/rh/health-library/document-viewer/?id=aa35720

Coagulation and Blood Transfusion | SpringerLinkCoagulation and Blood Transfusion | SpringerLink

Today marks the third lustrum of the annual international sympo- sium on blood transfus ... Coagulation and Blood Transfusion. Proceedings of the Fifteenth Annual Symposium on Blood Transfusion, Groningen 1990, ... Today marks the third lustrum of the annual international sympo- sium on blood transfusion, organized by the Rode Kruis ... The Use of Aprotinin in Cardiopulmonary Bypass and the Impact on Hemostasis and Blood Transfusion ...
more infohttps://link.springer.com/book/10.1007%2F978-1-4615-3900-1
  • You are encouraged to discuss your particular need for transfusion as well as the risks of transfusion with your doctor. (medicinenet.com)
  • To promote the safety and accessibility of blood and reduce the risks associated with transfusion WHO collaborated with the Ministry of Health (MoH) to review National Blood Policy and Strategic Plan, adapt normative guidelines and standards and forms for the National Blood Transfusion Services from 27 November to 1 December 2017. (who.int)
  • Because each unit of blood given carries risks, a trigger level lower than that, at 70 to 80 g/L, is now usually used, as it has been shown to have better patient outcomes. (wikipedia.org)
  • The risks will be explained before having a transfusion, unless this isn't possible - for example, if you need an emergency transfusion. (www.nhs.uk)
  • This review puts these risks in perspective (table) and describes the new measures that have been introduced to improve blood safety. (bmj.com)
  • Getting a blood transfusion is safe, but there are a few possible risks involved. (webmd.com)
  • There are theoretical risks of getting an infection from a transfusion, but these are very uncommon. (rainbowkids.com)
  • FDA has licensed two blood donor screening tests to detect Zika virus RNA in human plasma: the cobas Zika Test performed on the cobas 6800/8800 (Roche Molecular Systems, Inc) on October 5, 2017 and the Procleix Zika Virus Assay (Grifols Diagnostic Solutions, Inc.) on July 5, 2018. (cdc.gov)
  • as a resource to facilitate investigating and tracking potential transfusion-associated cases of infection (e.g., by public health departments). (cdc.gov)
  • White blood cells are part of the immune system, and its main defense against infection. (rchsd.org)
  • Some infectious agents, such as HIV, can survive in blood and infect the person receiving the blood transfusion. (medlineplus.gov)
  • One way CDC plays an important role in keeping the blood supply safe is by assisting state and local health departments and hospitals in investigating reports of potential infectious disease transmission. (cdc.gov)
  • This blood is then tested for infectious diseases before it is allowed to be used. (medlineplus.gov)
  • Volunteer donor blood usually is readily available, and when properly tested has a low incidence of adverse events. (medicinenet.com)
  • Your immune system attacks the transfused red blood cells because the donor blood type is not a good match. (drugs.com)
  • You might need further blood testing to see how your body is responding to the donor blood and to check your blood counts. (drugs.com)
  • Most of the time, you need to arrange with your hospital or local blood bank before your surgery to have directed donor blood. (medlineplus.gov)
  • Red blood cells, the most commonly transfused part, are used to increase the blood's ability to carry oxygen and prevent tiredness and other complications. (kidshealth.org)
  • To prevent complications from an existing blood or bleeding disorder , such as sickle cell disease , thalassemia, or anemia caused by kidney disease , hemophilia , or von Willebrand disease . (kidshealth.org)
  • Blood transfusions are generally considered safe, but there is some risk of complications. (drugs.com)
  • People who have hemophilia , a disease that affects the blood's ability to clot, need plasma or the clotting factors contained in plasma to help their blood clot and prevent internal bleeding. (rchsd.org)
  • It has the advantage of eliminating or minimizing the need for someone else's blood during and after surgery. (medicinenet.com)
  • If during the transfusion you have symptoms of shortness of breath , itching , fever or chills or just not feeling well, alert the person transfusing the blood immediately. (medicinenet.com)
  • The administration of a single unit of blood is the standard for hospitalized people who are not bleeding, with this treatment followed with re-assessment and consideration of symptoms and hemoglobin concentration. (wikipedia.org)
  • One may consider transfusion for people with symptoms of cardiovascular disease such as chest pain or shortness of breath. (wikipedia.org)
  • Your doctor will decide whether to start you or your child on blood transfusions based on your symptoms and hemoglobin level. (webmd.com)
  • This hormone helps stimulate bone marrow production of red blood cells, thus increasing hemoglobin levels and alleviating symptoms, such as fatigue, that are associated with anemia. (thebody.com)
  • Although in most situations the likelihood of a blood transfusion associated with surgery is uncommon, at times patients may require blood products. (medicinenet.com)
  • With funding from the Government of Japan, WHO supports the Ministry of Health to strengthen the National Blood Transfusion Services in South Sudan in the areas of voluntary unpaid blood donor recruitment and retention as well as capacity building to increase blood donations and improve availability to more hospitals in the country. (who.int)
  • WHO is committed to support the Ministry of Health to develop a conducive policy framework, standards and guidelines to direct the implementation and roll out of the National Blood Transfusion Services to other regional, state and county hospitals as well as utilizing the mobile/virtual blood banks in situations where there is no electrical power and blood cold chain facilities. (who.int)
  • The device is fully integrated with Mediware's HCLL Transfusion blood bank software that enables hospitals to share patients' transfusion and blood use data with core hospital systems, including electronic medical records. (informationweek.com)
  • Intraoperative blood salvage (autologous) or cell-saver scavenging , a method of picking up blood that has spilled from the circulatory system into an open wound, cleaning and re-infusing it. (wikipedia.org)
  • However, these hazards may be completely eliminated in nonemergency operations by the process of autotransfusion, whereby a patient's own blood is donated, stored, and given back when needed. (lightplanet.com)
  • Sometimes, when people know in advance that they are going to need a transfusion (for a planned surgery, for example), they may donate their own blood beforehand. (kidshealth.org)
  • Some people worry about getting diseases from infected blood, but the United States has one of the safest blood supplies in the world. (kidshealth.org)
  • In fact, about 5 million people each year in the United States get blood transfusions. (rchsd.org)
  • In the United States, the blood supply for transfusions comes from people who volunteer to donate their blood . (rchsd.org)
  • The efficacy of the blood transfusion treatment is still really based on the animal studies, and the small study size is problematic "because we know people sometimes react really well just to being in a trial, because of all the monitoring and all that," James Hendrix, PhD, director of global science initiatives at the Alzheimer's Association, told Healthline. (healthline.com)
  • This is when a family member or friend with a compatible blood type donates blood specifically for use by a designated patient. (kidshealth.org)
  • This is when a family member or friend donates blood specifically to be used by a designated patient. (rchsd.org)
  • If you get the wrong type of blood, your immune system -- your body's defense against germs -- could see it as dangerous and attack it. (webmd.com)
  • Another test checks your blood for other antibodies that could make your immune system react to the donated blood. (webmd.com)
  • Sometimes the immune system reacts to the transfusion. (webmd.com)
  • Patients with poor oxygen saturation may need more blood. (wikipedia.org)
  • As blood circulates, it delivers oxygen and nutrients throughout the body. (kidshealth.org)
  • As blood moves throughout the body, it carries oxygen and nutrients to all the places they're needed. (rchsd.org)
  • The Premature Infants in Need of Transfusion (PINT) study: a randomized, controlled trial of a restrictive (low) versus liberal (high) transfusion threshold for extremely low birth weight infants. (rainbowkids.com)
  • Your medical team will carefully match you to your donor's blood based on these antibodies. (webmd.com)
  • In emergencies, there are exceptions to the rule that the donor's blood type must match the recipient's exactly. (rchsd.org)
  • To date, there have been no confirmed transfusion-transmission cases of Zika virus in the United States. (cdc.gov)
  • 1. Busch M. Closing the windows on viral transmission by blood transfusion. (rainbowkids.com)
  • During surgery, you may need a blood transfusion because of blood loss. (medlineplus.gov)
  • If you are having a surgery that you're able to schedule months in advance, your doctor may ask whether you would like to use your own blood, instead of donated blood. (medlineplus.gov)
  • If so, you will need to have blood drawn one or more times before the surgery. (medlineplus.gov)
  • donating your own blood before surgery. (medicinenet.com)
  • The blood bank draws your blood and stores it until you need it during or after surgery. (medicinenet.com)
  • Blood transfusion is one of the therapeutic procedures performed during hospitalizations and undoubtedly helps patients who are injured, having surgery, receiving treatments or are being treated for diseases that affect the blood. (who.int)
  • Loss of blood during surgery or from an injury or an illness. (kidshealth.org)
  • Blood transfusion is a medical treatment to replace blood or portions of the blood lost through injury, surgery, or disease. (rexhealth.com)
  • This method involves a family member or friend donating blood before a planned surgery. (medlineplus.gov)
  • This blood is then set aside and held only for you, if you need a blood transfusion after surgery. (medlineplus.gov)
  • You can have blood taken from 6 weeks to 5 days before your surgery. (medlineplus.gov)
  • If your blood is not used during or after surgery, it will be thrown away. (medlineplus.gov)
  • For a type called beta thalassemia intermedia, you may need transfusions at certain times, like when you're sick or before you have surgery. (webmd.com)
  • Transfusions are used for various medical conditions to replace lost components of the blood. (wikipedia.org)
  • Our review is based on information from the annual reports of Serious Hazards of Transfusion (www.shot.demon.co.uk/), the guidelines of the British Committee for Standards in Haematology (www.bcshguidelines.com/), and the chief medical officer's second "Better Blood Transfusion" meeting (www.doh.gov.uk/bbt2). (bmj.com)
  • Blood must not be eaten or transfused, even in the case of a medical emergency. (wikipedia.org)
  • Certain medical procedures involving blood are specifically prohibited by Jehovah's Witnesses' blood doctrine. (wikipedia.org)
  • That's why before your transfusion, your medical team will match you with the right blood type. (webmd.com)
  • Medical teams use it in situations when patients need a transfusion but their blood type is unknown. (rchsd.org)